TY 2010 Form 990

- TIN:

Form990

Department of the Treasury
Internal Revenue Service

Return of Organization Exempt From Income Tax

Under section 501(c), 527, or 4947(a)(1) of the Internal Revenue Code (except black lung benefit trust or private foundation)

The organization may have to use a copy of this return to satisfy state reporting requirements.

OMB No. 1545-0047

2010

Open to Public Inspection

A For the calendar year, or tax year beginning 07-01-2010 and ending 06-30-2011

BCheck if applicable: Address change Name change Initial return Terminated Amended return Application pending

CName of organization
CANCER RESEARCH INSTITUTE

Doing Business As

Number and street (or P.O. box if mail is not delivered to street address)
55 BROADWAY SUITE 1802

Room/suite

City or town, state or country, and ZIP + 4
NEW YORK, NY10006

D Employer identification number

13-1837442

E Telephone number

G Gross receipts $ 28,007,949

F Name and address of principal officer:
JILL O'DONNELL-TORMEY CEO
55 BROADWAY SUITE 1802
NEW YORK,NY10006

Tax-exempt status: 501(c)(3) 501(c) ( ) LeftBullet

(insert no.) 4947(a)(1) or 527

Website:

www.cancerresearch.org

H(a)

Is this a group return for
affiliates? Yes No

H(b)

Are all affiliates included?

Yes No

If "No," attach a list. (see instructions)

H(c)

Group exemption number MediumBullet

K Form of organization: Corporation Trust Association Other MediumBullet

L Year of formation: 1953

M State of legal domicile: NY

Part I

Summary

1	Briefly describe the organization’s mission or most significant activities: THE CANCER RESEARCH INSTITUTE IS DEDICATED EXCLUSIVELY TO SUPPORTING RESEARCH AND DEVELOPMENT EFFORTS THAT WILL HELP TO HARNESS THE POWER OF THE IMMUNE SYSTEM TO DIAGNOSE, TREAT, AND CURE CANCER.
2	Check this box
3	Number of voting members of the governing body (Part VI, line 1a) ....	3	32
4	Number of independent voting members of the governing body (Part VI, line 1b) ....	4	32
5	Total number of individuals employed in calendar year 2010 (Part V, line 2a) ...	5	20
6	Total number of volunteers (estimate if necessary) ....	6	125
7a	Total unrelated business revenue from Part VIII, column (C), line 12 ..	7a	0
b	Net unrelated business taxable income from Form 990-T, line 34 ..	7b	0

		Prior Year	Current Year
8	Contributions and grants (Part VIII, line 1h) .........	13,374,848	14,808,431
9	Program service revenue (Part VIII, line 2g) .........	0	0
10	Investment income (Part VIII, column (A), lines 3, 4, and 7d ) ....	261,904	666,302
11	Other revenue (Part VIII, column (A), lines 5, 6d, 8c, 9c, 10c, and 11e)	48,736	87,415
12	Total revenue—add lines 8 through 11 (must equal Part VIII, column (A), line 12)...................	13,685,488	15,562,148
13	Grants and similar amounts paid (Part IX, column (A), lines 1–3 )...	9,528,298	11,000,359
14	Benefits paid to or for members (Part IX, column (A), line 4) ....	0	0
15	Salaries, other compensation, employee benefits (Part IX, column (A), lines 5–10)	2,311,692	2,321,319
16a	Professional fundraising fees (Part IX, column (A), line 11e)....	106,027	85,915
b	Total fundraising expenses (Part IX, column (D), line 25) 1,370,868
17	Other expenses (Part IX, column (A), lines 11a–11d, 11f–24f)....	1,994,057	2,180,206
18	Total expenses. Add lines 13–17 (must equal Part IX, column (A), line 25)	13,940,074	15,587,799
19	Revenue less expenses. Subtract line 18 from line 12......	-254,586	-25,651
		Beginning of Current Year	End of Year
20	Total assets (Part X, line 16)............	45,520,143	48,860,406
21	Total liabilities (Part X, line 26)............	23,673,087	23,003,882
22	Net assets or fund balances. Subtract line 21 from line 20 .....	21,847,056	25,856,524

Part II

Signature Block

Under penalties of perjury, I declare that I have examined this return, including accompanying schedules and statements, and to the best of my knowledge and belief, it is true, correct, and complete. Declaration of preparer (other than officer) is based on all information of which preparer has any knowledge.

Sign Here

	Signature of officer	Date

	Type or print name and title.

Paid Preparer's Use Only	Preparer's signature	Date	Check if self- employed	Preparer’s taxpayer identification number (see instructions)
	Firm’s name (or yours if self-employed), address, and ZIP + 4			EIN
				Phone no.

May the IRS discuss this return with the preparer shown above? (see instructions) ......... Yes No

For Privacy Act and Paperwork Reduction Act Notice, see the separate instructions.

Cat. No. 11282Y

Form 990 (2010)

Page 2

Part III

Statement of Program Service Accomplishments

Check if Schedule O contains a response to any question in this Part III . . . . . . . . . .

Briefly describe the organization’s mission: THE CANCER RESEARCH INSTITUTE IS THE WORLD'S ONLY NON-PROFIT ORGANIZATION DEDICATED EXCLUSIVELY TO TRANSFORMING CANCER PATIENT CARE BY ADVANCING LABORATORY, TRANSLATIONAL, AND CLINICAL RESEARCH EFFORTS AIMED AT LEARNING HOW TO HARNESS THE POWER OF THE IMMUNE SYSTEM TO DIAGNOSE, TREAT, AND CURE CANCER. THE INSTITUTE ALSO COORDINATES SCIENTIFIC AND MEDICAL CONFERENCES ON THE SUBJECTS OF IMMUNOLOGY, TUMOR IMMUNOLOGY, AND IMMUNOTHERAPY, AND DISSEMINATES INFORMATION ABOUT ADVANCES IN TUMOR IMMUNOLOGY TO THE MEDIA, PUBLIC, AND MEDICAL AND SCIENTIFIC COMMUNITIES.

Did the organization undertake any significant program services during the year which were not listed on
the prior Form 990 or 990-EZ? .................... Yes No

If “Yes,” describe these new services on Schedule O.

Did the organization cease conducting, or make significant changes in how it conducts, any program services? .......................... Yes No

If “Yes,” describe these changes on Schedule O.

Describe the exempt purpose achievements for each of the organization’s three largest program services by expenses.
Section 501(c)(3) and 501(c)(4) organizations and section 4947(a)(1) trusts are required to report the amount of grants and allocations to others, the total expenses, and revenue, if any, for each program service reported.


4a	(Code: ) (Expenses $ 5,900,000 including grants of $ 5,900,000 ) (Revenue $ )
	RESEARCH IN BASIC IMMUNOLOGY AND EXPERIMENTAL TUMOR IMMUNOLOGY HAS PROGRESSED OVER THE PAST 50 YEARS TO A POINT WHERE DISCOVERIES MADE IN THE LABORATORY NOW PROVIDE THE RATIONALE FOR THE CLINICAL TESTING OF IMMUNE-BASED THERAPIES IN CANCER PATIENTS. THIS EVOLUTIONARY TRANSITION FROM THE LABORATORY TO THE CLINIC SIGNALS THE EMERGENCE OF A NEW ERA IN CANCER THERAPY. TO SPEED CLINICAL DISCOVERY, THE CANCER RESEARCH INSTITUTE CONCEIVED A NOVEL PROGRAM FOR CLINICALLY RELATED RESEARCH WITH "COLLABORATION" AND "INNOVATION" AS ITS CORNERSTONE. THREE PROGRAMS COMPRISE THIS CLINICAL INVESTIGATION PROGRAM: COORDINATED CANCER INITIATIVES (CCI), CANCER VACCINE COLLABORATIVE (CVC), AND THE CANCER IMMUNOTHERAPY CONSORTIUM (CIC). TOGETHER THIS PROGRAM HAS AT ITS ULTIMATE GOAL THE DEVELOPMENT OF SAFE AND EFFECTIVE IMMUNOTHERAPIES FOR CANCER. THROUGH THE CCI, CRI IDENTIFIES SCIENTIFIC EXPERTS FROM VARIOUS DISCIPLINES AND MOBILIZES THEM TO WORK COOPERATIVELY ON DEFINED TASKS TOWARD COMMON GOALS. THIS STRATEGIC FUNDING PROGRAM PROVIDES A PROACTIVE AND FLEXIBLE WAY FOR CRI TO FOCUS ON AREAS OF GREATEST NEED THAT ALSO ARE DEEMED ABLE TO PROVIDE CLINICALLY RELEVANT INSIGHTS AND DISCOVERIES THAT COULD POTENTIALLY ACCELERATE THE DEVELOPMENT OF SAFE AND EFFECTIVE CANCER IMMUNOTHERAPIES. THE CVC IS A COORDINATED GLOBAL NETWORK OF ACADEMIC CLINICAL TRIAL SITES WITH SPECIAL EXPERTISE IN IMMUNOLOGY CONDUCTING PARALLEL, EARLY-STAGE CLINICAL TRIALS TO IDENTIFY THE OPTIMAL COMPOSITION AND DELIVERY METHOD OF SUCCESSFUL THERAPEUTIC CANCER VACCINES AND OTHER IMMUNOTHERAPIES. THIS PROGRAM IS SUPPORTED IN PART THROUGH A NEW CRI INITIATIVE CALLED THE CANCER VACCINE ACCELERATION FUND (CVAF), A VENTURE PHILANTHROPY PROGRAM THAT SPEEDS DISCOVERY AND DEVELOPMENT OF OPTIMAL CANCER IMMUNOTHERAPIES BY PROVIDING NEW OPPORTUNITIES FOR COLLABORATION BETWEEN ACADEMIC RESEARCHERS AND COMPANIES THAT CONTROL HIGHLY PROMISING THERAPEUTIC AGENTS, AND SUBSIDIZING PRODUCTION AND/OR PURCHASE OF THESE AGENTS FOR USE IN ACADEMIC CLINICAL TRIALS. CIC IS THE LEADING INITIATIVE ON CANCER VACCINE AND IMMUNOTHERAPY DISCOVERY AND DEVELOPMENT. ITS MISSION IS TO IMPROVE PATIENT CARE BY MAKING CANCER IMMUNOTHERAPY PART OF THE STANDARD-OF-CARE IN ONCOLOGY. CIC MEMBERS INCLUDE MANY OF THE WORLD'S MOST INNOVATIVE PHARMACEUTICAL, BIOTECHNOLOGY, AND ACADEMIC INSTITUTIONS. THROUGH COLLABORATION, INTERACTION, AND COMMUNITY CONSENSUS BUILDING, THESE EFFORTS ESTABLISH A UNIFIED VOICE IN THE CANCER IMMUNOTHERAPY FIELD AND PROVIDE A MAJOR NEW RESOURCE TO ACADEMIA, INDUSTRY, AND GOVERNMENTAL AGENCIES INVOLVED IN CANCER IMMUNOTHERAPY DEVELOPMENT.

4b	(Code: ) (Expenses $ 2,860,359 including grants of $ 2,860,359 ) (Revenue $ )
	CRI'S IRVINGTON INSTITUTE POSTDOCTORAL FELLOWSHIP PROGRAM PROVIDES SUPPORT TO BRIGHT YOUNG SCIENTISTS ENABLING THEM TO EMBARK ON A CAREER IN IMMUNOLOGY RESEARCH. CRI FELLOWS HAVE DIFFERENT RESEARCH INTERESTS AND CONDUCT THEIR WORK IN LABORATORIES AROUND THE WORLD, UNDER THE GUIDANCE OF FIELD-LEADING MENTORS WHO COMPLETE THE FELLOW'S LABORATORY TRAINING. THEIR RESEARCH SUPPORTS CRI'S DRIVING MISSION TO CONQUER CANCER THROUGH IMMUNOLOGY BY INCREASING OUR UNDERSTANDING OF THE IMMUNE SYSTEM AND ITS POTENTIAL TO CONTROL CANCER. THESE YOUNG RESEARCHERS BRING FRESH INSIGHT AND ENTHUSIASM TO THEIR WORK, CARRYING OUT IMPORTANT SEMINAL STUDIES THAT PROVIDE THE SCIENTIFIC FOUNDATION FOR THE NEXT WAVE OF MAJOR DISCOVERIES IN THE FIELD.

4c	(Code: ) (Expenses $ 800,000 including grants of $ 800,000 ) (Revenue $ )
	THE INVESTIGATOR AWARD PROGRAM COMPLEMENTS OUR FELLOWSHIP PROGRAM BY PROVIDING MULTI-YEAR SUPPORT TO ACCOMPLISHED ASSISTANT PROFESSORS WHO ARE UNDERTAKING THEIR FIRST INDEPENDENT STUDIES IN BASIC AND TUMOR IMMUNOLOGY. FUNDING FROM THIS PROGRAM OFFERS FLEXIBILITY AND A DEGREE OF STABILITY DURING THIS VERY CHALLENGING PERIOD IN AN ACADEMIC SCIENTIST'S CAREER.

4d	Other program services. (Describe in Schedule O.)
	(Expenses $ 3,631,783 including grants of $ 1,390,000 ) (Revenue $ )
4e	Total program service expenses$ 13,192,142

Form 990 (2010)

Page 3

Part IV

Checklist of Required Schedules

Yes

Is the organization described in section 501(c)(3) or 4947(a)(1) (other than a private foundation)? If “Yes,” complete Schedule A Click to see attachment

.....................

Yes

Is the organization required to complete Schedule B, Schedule of Contributors? Click to see attachment

........

Yes

Did the organization engage in direct or indirect political campaign activities on behalf of or in opposition to candidates for public office? If “Yes,” complete Schedule C, Part I..........

Section 501(c)(3) organizations. Did the organization engage in lobbying activities? If “Yes,” complete Schedule C,
Part II.........................

Is the organization a section 501(c)(4), 501(c)(5), or 501(c)(6) organization that receives membership dues, assessments, or similar amounts as defined in Revenue Procedure 98-19? If “Yes,” complete Schedule C, Part III........................

Did the organization maintain any donor advised funds or any similar funds or accounts where donors have the right to provide advice on the distribution or investment of amounts in such funds or accounts? If “Yes,” complete
Schedule D, Part I Click to see attachment

.......................

Did the organization receive or hold a conservation easement, including easements to preserve open space,
the environment, historic land areas or historic structures? If “Yes,” complete Schedule D, Part II Click to see attachment

...

Did the organization maintain collections of works of art, historical treasures, or other similar assets? If “Yes,” complete Schedule D, Part III Click to see attachment

....................

Did the organization report an amount in Part X, line 21; serve as a custodian for amounts not listed in Part X; or provide credit counseling, debt management, credit repair, or debt negotiation services? If “Yes,”
complete Schedule D, Part IV Click to see attachment

...................

Did the organization, directly or through a related organization, hold assets in term, permanent,or quasi-endowments? If “Yes,” complete Schedule D, Part V Click to see attachment

Yes

If the organization’s answer to any of the following questions is ‘Yes,’ then complete Schedule D, Parts VI, VII, VIII, IX, or X as applicable:

Did the organization report an amount for land, buildings, and equipment in Part X, line10? If “Yes,” complete Schedule D, Part VI. Click to see attachment

11a

Yes

Did the organization report an amount for investments—other securities in Part X, line 12 that is 5% or more of its total assets reported in Part X, line 16? If “Yes,” complete Schedule D, Part VII. Click to see attachment

11b

Yes

Did the organization report an amount for investments—program related in Part X, line 13 that is 5% or more of its total assets reported in Part X, line 16? If “Yes,” complete Schedule D, Part VIII. Click to see attachment

11c

Did the organization report an amount for other assets in Part X, line 15 that is 5% or more of its total assets reported in Part X, line 16? If “Yes,” complete Schedule D, Part IX. Click to see attachment

11d

Did the organization report an amount for other liabilities in Part X, line 25? If “Yes,” complete Schedule D, Part X. Click to see attachment

11e

Yes

Did the organization’s separate or consolidated financial statements for the tax year include a footnote that addresses the organization’s liability for uncertain tax positions under FIN 48 (ASC 740)? If “Yes,” complete Schedule D, Part X. Click to see attachment

11f

Yes

12a

Did the organization obtain separate, independent audited financial statements for the tax year? If “Yes,” complete Schedule D, Parts XI, XII, and XIII Click to see attachment

12a

Yes

Was the organization included in consolidated, independent audited financial statements for the tax year? If “Yes,” and if the organization answered ‘No’ to line 12a, then completing Schedule D, Parts XI, XII, and XIII is optional Click to see attachment

12b

Is the organization a school described in section 170(b)(1)(A)(ii)? If “Yes,” complete Schedule E

14a

Did the organization maintain an office, employees, or agents outside of the United States?....

14a

Did the organization have aggregate revenues or expenses of more than $10,000 from grantmaking, fundraising, business, and program service activities outside the United States? If “Yes,” complete Schedule F, Part I......... Click to see attachment

14b

Did the organization report on Part IX, column (A), line 3, more than $5,000 of grants or assistance to any organization or entity located outside the U.S.? If “Yes,” complete Schedule F, Part II.. Click to see attachment

Yes

Did the organization report on Part IX, column (A), line 3, more than $5,000 of aggregate grants or assistance to individuals located outside the U.S.? If “Yes,” complete Schedule F, Part III.. Click to see attachment

Did the organization report a total of more than $15,000, of expenses for professional fundraising services on Part IX, column (A), lines 6 and 11e? If “Yes,” complete Schedule G, Part I Click to see attachment

Yes

Did the organization report more than $15,000 total of fundraising event gross income and contributions on Part VIII, lines 1c and 8a? If “Yes,” complete Schedule G, Part II.......... Click to see attachment

Yes

Did the organization report more than $15,000 of gross income from gaming activities on Part VIII, line 9a? If “Yes,” complete Schedule G, Part III................... Click to see attachment

Form 990 (2010)

Page 4

Part IV

Checklist of Required Schedules (continued)

20a

Did the organization operate one or more hospitals? If “Yes,” complete Schedule H.....

20a

Did the organization attach its audited financial statement to this return? Note: All Form 990 filers that operate one or more hospitals must attach audited financial statements. .....

20b

Did the organization report more than $5,000 of grants and other assistance to governments and organizations in the United States on Part IX, column (A), line 1? If “Yes,” complete Schedule I, Parts I and II.. Click to see attachment

Yes

Did the organization report more than $5,000 of grants and other assistance to individuals in the United States on Part IX, column (A), line 2? If “Yes,” complete Schedule I, Parts I and III..... Click to see attachment

Did the organization answer “Yes” to Part VII, Section A, questions 3, 4, or 5, about compensation of the organization’s current and former officers, directors, trustees, key employees, and highest compensated employees? If “Yes,” complete Schedule J................ Click to see attachment

Yes

24a

Did the organization have a tax-exempt bond issue with an outstanding principal amount of more than $100,000 as of the last day of the year, that was issued after December 31, 2002? If “Yes,” answer questions 24b–24d and complete Schedule K. If “No,” go to line 25................

24a

Did the organization invest any proceeds of tax-exempt bonds beyond a temporary period exception?...

24b

Did the organization maintain an escrow account other than a refunding escrow at any time during the year
to defease any tax-exempt bonds?......................

24c

Did the organization act as an “on behalf of” issuer for bonds outstanding at any time during the year?...

24d

25a

Section 501(c)(3) and 501(c)(4) organizations. Did the organization engage in an excess benefit transaction with a disqualified person during the year? If “Yes,” complete Schedule L, Part I......

25a

Is the organization aware that it engaged in an excess benefit transaction with a disqualified person in a prior year, and that the transaction has not been reported on any of the organization’s prior Forms 990 or 990-EZ? If “Yes,” complete Schedule L, Part I................

25b

Was a loan to or by a current or former officer, director, trustee, key employee, highly compensated employee, or disqualified person outstanding as of the end of the organization’s tax year? If “Yes,” complete Schedule L,
Part II...........................

Did the organization provide a grant or other assistance to an officer, director, trustee, key employee, substantial contributor, or a grant selection committee member, or to a person related to such an individual? If “Yes,” complete Schedule L, Part III...............

Was the organization a party to a business transaction with one of the following parties? (see Schedule L, Part IV instructions for applicable filing thresholds, conditions, and exceptions):

A current or former officer, director, trustee, or key employee? If “Yes,” complete Schedule L, Part IV .........................

28a

A family member of a current or former officer, director, trustee, or key employee? If “Yes,”
complete Schedule L, Part IV...................

28b

An entity of which a current or former officer, director, trustee, or key employee (or a family member thereof) was an officer, director, trustee, or owner? If “Yes,” complete Schedule L, Part IV..

28c

Did the organization receive more than $25,000 in non-cash contributions? If “Yes,” complete Schedule M Click to see attachment

Yes

Did the organization receive contributions of art, historical treasures, or other similar assets, or qualified conservation contributions? If “Yes,” complete Schedule M............ Click to see attachment

Did the organization liquidate, terminate, or dissolve and cease operations? If “Yes,” complete Schedule N,
Part I........................... Click to see attachment

Did the organization sell, exchange, dispose of, or transfer more than 25% of its net assets? If “Yes,” complete Schedule N, Part II.......................

Did the organization own 100% of an entity disregarded as separate from the organization under Regulations sections 301.7701-2 and 301.7701-3? If “Yes,” complete Schedule R, Part I........

Was the organization related to any tax-exempt or taxable entity? If “Yes,” complete Schedule R, Parts II, III, IV, and V, line 1.....................

Is any related organization a controlled entity within the meaning of section 512(b)(13)? .....

Did the organization receive any payment from or engage in any transaction with a controlled entity within the meaning of section 512(b)(13)? If “Yes,” complete Schedule R, Part V, line 2... YesNo

Section 501(c)(3) organizations. Did the organization make any transfers to an exempt non-charitable related organization? If “Yes,” complete Schedule R, Part V, line 2...........

Did the organization conduct more than 5% of its activities through an entity that is not a related organization and that is treated as a partnership for federal income tax purposes? If “Yes,” complete Schedule R, Part VI

Did the organization complete Schedule O and provide explanations in Schedule O for Part VI, lines 11 and 19? Note. All Form 990 filers are required to complete Schedule O. ............

Yes

Form 990 (2010)

Page 5

Part V

Statements Regarding Other IRS Filings and Tax Compliance

Check if Schedule O contains a response to any question in this Part V . . . . . . . . . .

Yes

Enter the number reported in Box 3 of Form 1096. Enter -0- if not applicable. .......

Enter the number of Forms W-2G included in line 1a. Enter -0- if not applicable.

Did the organization comply with backup withholding rules for reportable payments to vendors and reportable gaming (gambling) winnings to prize winners? ..................

Yes

Enter the number of employees reported on Form W-3, Transmittal of Wage and Tax Statements filed for the calendar year ending with or within the year covered by this return .....................

If at least one is reported on line 2a, did the organization file all required federal employment tax returns?

Note. If the sum of lines 1a and 2a is greater than 250, you may be required to e-file. (see instructions)

Yes

Did the organization have unrelated business gross income of $1,000 or more during the year?.............................

If “Yes,” has it filed a Form 990-T for this year? If “No,” provide an explanation in Schedule O.....

At any time during the calendar year, did the organization have an interest in, or a signature or other authority over, a financial account in a foreign country (such as a bank account or securities account)?.......................

Yes

If "Yes," enter the name of the foreign country: MediumBullet

CJ , EI , MP
See instructions for filing requirements for Form TD F 90-22.1, Report of Foreign Bank and Financial Accounts.

Was the organization a party to a prohibited tax shelter transaction at any time during the tax year?..

Did any taxable party notify the organization that it was or is a party to a prohibited tax shelter transaction?

If “Yes” to line 5a or 5b, did the organization file Form 8886-T? ........

Does the organization have annual gross receipts that are normally greater than $100,000, and did the organization solicit any contributions that were not tax deductible?..........

If “Yes,” did the organization include with every solicitation an express statement that such contributions or gifts were not tax deductible?........................

Organizations that may receive deductible contributions under section 170(c).

Did the organization receive a payment in excess of $75 made partly as a contribution and partly for goods and services provided to the payor?....................

Yes

If “Yes,” did the organization notify the donor of the value of the goods or services provided?.....

Yes

Did the organization sell, exchange, or otherwise dispose of tangible personal property for which it was required to file Form 8282?...........................

If “Yes,” indicate the number of Forms 8282 filed during the year ....

Did the organization receive any funds, directly or indirectly, to pay premiums on a personal benefit contract?..........................

Did the organization, during the year, pay premiums, directly or indirectly, on a personal benefit contract?..

If the organization received a contribution of qualified intellectual property, did the organization file Form 8899 as required?...................

If the organization received a contribution of cars, boats, airplanes, or other vehicles, did the organization file a Form 1098-C?...............

Sponsoring organizations maintaining donor advised funds and section 509(a)(3) supporting organizations. Did the supporting organization, or a donor advised fund maintained by a sponsoring organization, have excess business holdings at any time during the year?................

Sponsoring organizations maintaining donor advised funds.

Did the organization make any taxable distributions under section 4966?.........

Did the organization make a distribution to a donor, donor advisor, or related person?......

Section 501(c)(7) organizations. Enter:

Initiation fees and capital contributions included on Part VIII, line 12 ...

10a

Gross receipts, included on Form 990, Part VIII, line 12, for public use of club facilities

10b

Section 501(c)(12) organizations. Enter:

Gross income from members or shareholders .........

11a

Gross income from other sources (Do not net amounts due or paid to other sources against amounts due or received from them.) ........

11b

12a

Section 4947(a)(1) non-exempt charitable trusts. Is the organization filing Form 990 in lieu of Form 1041?

12a

If “Yes,” enter the amount of tax-exempt interest received or accrued during the year.

12b

Section 501(c)(29) qualified nonprofit health insurance issuers.

Is the organization licensed to issue qualified health plans in more than one state?
Note. All 501(c)(29) organizations must list in Schedule O each state in which they are licensed to issue qualified health plans, the amount of reserves required by each state, and the amount of reserves the organization allocated to each state.

13a

Enter the aggregate amount of reserves the organization is required to maintain by the states in which the organization is licensed to issue qualified health plans.

13b

Enter the aggregate amount of reserves on hand.

13c

14a

Did the organization receive any payments for indoor tanning services during the tax year?.....

14a

If "Yes," has it filed a Form 720 to report these payments? If “No,” provide an explanation in Schedule O..

14b

Form 990 (2010)

Page 6

Part VI

Governance, Management, and Disclosure For each “Yes” response to lines 2 through 7b below, and for a “No” response to lines 8a, 8b, or 10b below, describe the circumstances, processes, or changes in Schedule O. See instructions.

Check if Schedule O contains a response to any question in this Part VI . . . . . . . . . .

Section A. Governing Body and Management

Yes

Enter the number of voting members of the governing body at the end of the tax year ..............

Enter the number of voting members included in line 1a, above, who are independent .................

Did any officer, director, trustee, or key employee have a family relationship or a business relationship with any other officer, director, trustee, or key employee? .................

Did the organization delegate control over management duties customarily performed by or under the direct supervision of officers, directors or trustees, or key employees to a management company or other person? ..

Did the organization make any significant changes to its governing documents since the prior Form 990 was filed?

Did the organization become aware during the year of a significant diversion of the organization’s assets? .

Does the organization have members or stockholders? ................

Does the organization have members, stockholders, or other persons who may elect one or more members of the governing body? .........................

Are any decisions of the governing body subject to approval by members, stockholders, or other persons? ..

Did the organization contemporaneously document the meetings held or written actions undertaken during the year by the following:

The governing body? .........................

Yes

Each committee with authority to act on behalf of the governing body? ............

Yes

Is there any officer, director, trustee, or key employee listed in Part VII, Section A, who cannot be reached at the organization’s mailing address? If “Yes,” provide the names and addresses in Schedule O .....

Section B. Policies (This Section B requests information about policies not required by the Internal
Revenue Code.)

Yes

10a

Does the organization have local chapters, branches, or affiliates? ............

10a

If “Yes,” does the organization have written policies and procedures governing the activities of such chapters, affiliates, and branches to ensure their operations are consistent with those of the organization? ....

10b

11a

Has the organization provided a copy of this Form 990 to all members of its governing body before filing the form?

11a

Describe in Schedule O the process, if any, used by the organization to review the Form 990. .....

12a

Does the organization have a written conflict of interest policy? If “No,” go to line 13.......

12a

Yes

Are officers, directors or trustees, and key employees required to disclose annually interests that could give rise to conflicts? ...........................

12b

Yes

Does the organization regularly and consistently monitor and enforce compliance with the policy? If “Yes,” describe in Schedule O how this is done ....................

12c

Yes

Does the organization have a written whistleblower policy? ...............

Yes

Does the organization have a written document retention and destruction policy? .........

Yes

Did the process for determining compensation of the following persons include a review and approval by independent persons, comparability data, and contemporaneous substantiation of the deliberation and decision?

The organization’s CEO, Executive Director, or top management official ...........

15a

Yes

Other officers or key employees of the organization ................

15b

Yes

If "Yes" to line a or b, describe the process in Schedule O. (See instructions.)

16a

Did the organization invest in, contribute assets to, or participate in a joint venture or similar arrangement with a taxable entity during the year? ......................

16a

If “Yes,” has the organization adopted a written policy or procedure requiring the organization to evaluate its participation in joint venture arrangements under applicable federal tax law, and taken steps to safeguard the organization’s exempt status with respect to such arrangements? ............

16b

Section C. Disclosure

List the States with which a copy of this Form 990 is required to be filed MediumBullet

AZ , CA , CO , CT , DC , FL , GA , HI , IL , IA , MD , MI , MN , MS , MO , MT , NE , NH , NJ , NM , NY , NC , ND , OH , OR , PA , RI , SC , TN , UT , VA , WA , WV

Section 6104 requires an organization to make its Form 1023 (or 1024 if applicable), 990, and 990-T (501(c)(3)s only) available for public inspection. Indicate how you make these available. Check all that apply.

Own website Another's website Upon request

Describe in Schedule O whether (and if so, how), the organization makes its governing documents, conflict of interest policy, and financial statements available to the public.

State the name, physical address, and telephone number of the person who possesses the books and records of the organization: MediumBullet

ALFRED MASSIDAS
55 BROADWAY 18TH FL
NEW YORK,NY10006
(212) 688-7515

Form 990 (2010)

Page 7

Part VII

Compensation of Officers, Directors,Trustees, Key Employees, Highest Compensated Employees, and Independent Contractors

Check if Schedule O contains a response to any question in this Part VII . . . . . . . . . .

Section A. Officers, Directors, Trustees, Key Employees, and Highest Compensated Employees

1a Complete this table for all persons required to be listed. Report compensation for the calendar year ending with or within the organization’s tax year.
RoundBullet

List all of the organization’s current officers, directors, trustees (whether individuals or organizations), regardless of amount
of compensation, and current key employees. Enter -0- in columns (D), (E), and (F) if no compensation was paid.

List all of the organization’s current key employees, if any. See instructions for definition of "key employee."

List the organization’s five current highest compensated employees (other than an officer, director, trustee or key employee)
who received reportable compensation (Box 5 of Form W-2 and/or Box 7 of Form 1099-MISC) of more than $100,000 from the
organization and any related organizations.

List all of the organization’s former officers, key employees, or highest compensated employees who received more than $100,000
of reportable compensation from the organization and any related organizations.

List all of the organization’s former directors or trustees that received, in the capacity as a former director or trustee of the
organization, more than $10,000 of reportable compensation from the organization and any related organizations.

List persons in the following order: individual trustees or directors; institutional trustees; officers; key employees; highest
compensated employees; and former such persons.

Check this box if neither the organization nor any related organizations compensated any current or former officer, director, or trustee.

(A) Name and Title	(B) Average hours per week (describe hours for related organizations in Schedule O)	(C) Position (check all that apply)		(D) Reportable compensation from the organization (W- 2/1099-MISC)	(E) Reportable compensation from related organizations (W- 2/1099-MISC)	(F) Estimated amount of other compensation from the organization and related organizations
(A) Name and Title
(1) ANDREW M PAUL Trustee	1.0	X		0	0	0
(2) Donald J Gogel CHAIRMAN	2.0	X	X	0	0	0
(3) Patrick J McGrath Trustee	1.0	X		0	0	0
(4) Edgar R Berner Vice Chairman	2.0	X	X	0	0	0
(5) Julian H Robertson Vice Chairman	2.0	X	X	0	0	0
(6) Jacques C Nordeman Vice Chairman	1.0	X	X	0	0	0
(7) Richard M DeMartini Trustee	1.0	X		0	0	0
(8) Thomas G Mendell Secretary	1.0	X		0	0	0
(9) Peter L Bloom Trustee	1.0	X		0	0	0
(10) Brian J Brille Trustee	1.0	X		0	0	0
(11) Geoffrey O Coley Trustee	1.0	X		0	0	0
(12) Sandra Coudert Trustee	1.0	X		0	0	0
(13) Maurice J Cunniffe Trustee	1.0	X		0	0	0
(14) Glenn J DeSimone Trustee	1.0	X		0	0	0
(15) Carlos A Ferrer Trustee	1.0	X		0	0	0
(16) John B Fitzgibbons TREASURER	2.0	X	X	0	0	0
(17) Margot E Freedman Trustee	1.0	X		0	0	0

Form 990 (2010)

Page 8

Part VII

Section A. Officers, Directors, Trustees, Key Employees, and Highest Compensated Employees (continued)

(A) Name and Title	(B) Average hours per week (describe hours for related organizations in Schedule O)	(C) Position (check all that apply)			(D) Reportable compensation from the organization (W- 2/1099-MISC)	(E) Reportable compensation from related organizations (W- 2/1099-MISC)	(F) Estimated amount of other compensation from the organization and related organizations
(A) Name and Title
(18) Oliver R Grace Jr Trustee	1.0	X			0	0	0
(19) Michael M Kellen Trustee	1.0	X			0	0	0
(20) Alexander P Lynch Trustee	1.0	X			0	0	0
(21) Lief D Rosenblatt Trustee	1.0	X			0	0	0
(22) Paul J Sekhri Trustee	1.0	X			0	0	0
(23) Paul C Shiverick Trustee	1.0	X			0	0	0
(24) Frank V Sica Trustee	1.0	X			0	0	0
(25) Heidi J Ueberroth Trustee	1.0	X			0	0	0
(26) Lauren Veronis Trustee	2.0	X			0	0	0
(27) JAMES M CITRIN Trustee	1.0	X			0	0	0
(28) GS BECKWITH GILBERT Trustee	1.0	X	X		0	0	0
(29) HOWARD SCHILLER Trustee	1.0	X			0	0	0
(30) MICHAEL B TARGOFF Trustee	1.0	X			0	0	0
(31) DIANE TUFT Trustee	1.0	X			0	0	0
(32) JAMES A WIATT Trustee	1.0	X			0	0	0
(33) Jill O'Donnell Tormey CEO	40.0		X		351,074	0	57,789
(34) Alfred R Massidas Controller & General Manager	40.0		X		238,276	0	47,089
(35) LYNNE A RAPINO DIR OF GRANTS ADMINISTRATION	40.0			X	189,120	0	42,189
(36) BRIAN M BREWER DIRECTOR OF COMMUNICATIONS	40.0			X	116,358	0	29,751
(37) ADAM M KOLOM DIRECTOR, CVAF	40.0			X	300,000	0	36,666

1b	Sub-Total................
c	Total from continuation sheets to Part VII, Section A....
d	Total (add lines 1b and 1c)............	1,194,828	0	213,484

Total number of individuals (including but not limited to those listed above) who received more than $100,000 in reportable compensation from the organization MediumBullet

Yes

Did the organization list any former officer, director or trustee, key employee, or highest compensated employee on line 1a? If “Yes,” complete Schedule J for such individual .............

For any individual listed on line 1a, is the sum of reportable compensation and other compensation from the organization and related organizations greater than $150,000? If “Yes,” complete Schedule J for such individual...........................

Yes

Did any person listed on line 1a receive or accrue compensation from any unrelated organization or individual for services rendered to the organization? If “Yes,” complete Schedule J for such person .....

Section B. Independent Contractors

Complete this table for your five highest compensated independent contractors that received more than $100,000 of compensation from the organization.

(A) Name and business address	(B) Description of services	(C) Compensation





2 Total number of independent contractors (including but not limited to those listed above) who received more than $100,000 in compensation from the organization 0

Form 990 (2010)

Page 9

Part VIII

Statement of Revenue

				(A) Total revenue	(B) Related or exempt function revenue	(C) Unrelated business revenue	(D) Revenue excluded from tax under sections 512, 513, or 514
1a	Federated campaigns..1a		769,588
b	Membership dues....1b
c	Fundraising events....1c		753,139
d	Related organizations...1d
e	Government grants (contributions)1e

f	All other contributions, gifts, grants, and similar amounts not included above1f		13,285,704
g	Noncash contributions included in lines 1a-1f:$ 482,894
h	Total. Add lines 1a-1f.......			14,808,431
			Business Code
2a
b
c
d
e
f	All other program service revenue .
g	Total. Add lines 2a–2f........			0
3	Investment income (including dividends, interest
	and other similar amounts).....			516,557			516,557
4	Income from investment of tax-exempt bond proceeds..			0
5	Royalties............			0
		(i) Real	(ii) Personal
6a	Gross Rents	164,267
b	Less: rental expenses	179,415
c	Rental income or (loss)	-15,148
d	Net rental income or (loss).......			-15,148			-15,148
		(i) Securities	(ii) Other
7a	Gross amount from sales of assets other than inventory	12,236,716
b	Less: cost or other basis and sales expenses	12,086,971
c	Gain or (loss)	149,745
d	Net gain or (loss)..........			149,745			149,745
8a	Gross income from fundraising events (not including $ 753,139 of contributions reported on line 1c). See Part IV, line 18 ...
	a		179,415
b	Less: direct expenses ...b		179,415
c	Net income or (loss) from fundraising events..			0
9a	Gross income from gaming activities. See Part IV, line 19 ...
	a
b	Less: direct expenses ...b
c	Net income or (loss) from gaming activities...			0
10a	Gross sales of inventory, less returns and allowances .
	a
b	Less: cost of goods sold ..b
c	Net income or (loss) from sales of inventory..			0
Miscellaneous Revenue			Business Code
11a	MISCELLANEOUS INCOME			17,425			17,425
b	CHANGE IN VALUE OF PERPETUAL TRUST			85,138			85,138
c
d	All other revenue ....
e	Total. Add lines 11a–11d ......			102,563
12	Total revenue. See Instructions....			15,562,148			753,717

Form 990 (2010)

Page 10

Part IX

Statement of Functional Expenses

Section 501(c)(3) and 501(c)(4) organizations must complete all columns. All other organizations must complete column (A) but are not required to complete columns (B), (C), and (D).

Do not include amounts reported on lines 6b, 7b, 8b, 9b, and 10b of Part VIII.		(A) Total expenses	(B) Program service expenses	(C) Management and general expenses	(D) Fundraising expenses
1	Grants and other assistance to governments and organizations in the U.S. See Part IV, line 21	9,464,859	9,464,859
2	Grants and other assistance to individuals in the U.S. See Part IV, line 22	0
3	Grants and other assistance to governments, organizations, and individuals outside the U.S. See Part IV, lines 15 and 16	1,535,500	1,535,500
4	Benefits paid to or for members	0
5	Compensation of current officers, directors, trustees, and key employees ....	603,300	240,480	217,860	144,960
6	Compensation not included above, to disqualified persons (as defined under section 4958(f)(1)) and persons described in section 4958(c)(3)(B) ....	0
7	Other salaries and wages	1,198,211	562,273	223,130	412,808
8	Pension plan contributions (include section 401(k) and section 403(b) employer contributions) ....	153,190	64,912	41,271	47,007
9	Other employee benefits .......	269,604	105,968	73,480	90,156
10	Payroll taxes ...........	97,014	43,132	23,645	30,237
11	Fees for services (non-employees):
a	Management ......	0
b	Legal .........	77,875	74,300	3,575
c	Accounting ...........	75,000		75,000
d	Lobbying ...........	0
e	Professional fundraising. See Part IV, line 17..	85,915			85,915
f	Investment management fees ......	116,333		116,333
g	Other ..........	272,271	100,595	38,415	133,261
12	Advertising and promotion ....	306,396	179,333		127,063
13	Office expenses .......	274,058	95,158	57,934	120,966
14	Information technology ......	0
15	Royalties ..	0
16	Occupancy ...........	298,335	143,877	66,064	88,394
17	Travel ............	201,378	151,781	5,847	43,750
18	Payments of travel or entertainment expenses for any federal, state, or local public officials ......	0
19	Conferences, conventions, and meetings ....	368,268	368,268
20	Interest ...........	0
21	Payments to affiliates .......	0
22	Depreciation, depletion, and amortization .....	71,176	27,481	19,054	24,641
23	Insurance ..............	22,841		22,841
24	Other expenses. Itemize expenses not covered above. (Expenses grouped together and labeled miscellaneous may not exceed 5% of total expenses shown on line 25 below.)
a	RESEARCH PROGRAM SUPPORT EXP	12,774	12,774
b	MISCELLANEOUS	83,501	21,451	40,340	21,710
c
d
e
f	All other expenses
25	Total functional expenses. Add lines 1 through 24f	15,587,799	13,192,142	1,024,789	1,370,868
26	Joint costs. Check here if following SOP 98-2 (ASC 958-720). Complete this line only if the organization reported in column (B) joint costs from a combined educational campaign and fundraising solicitation	285,349	171,209		114,140

Form 990 (2010)

Page 11


				(A) Beginning of year		(B) End of year
1	Cashnon-interest-bearing ..........			1,828,133	1	3,463,396
2	Savings and temporary cash investments .......				2	249,872
3	Pledges and grants receivable, net .........			9,287,596	3	9,722,982
4	Accounts receivable, net .........				4
5	Receivables from current and former officers, directors, trustees, key employees, and highest compensated employees. Complete Part II of
	Schedule L ..........				5
6	Receivables from other disqualified persons (as defined under section 4958(f)(1)) and persons described in section 4958(c)(3)(B). Complete Part II of
	Schedule L ..........				6
7	Notes and loans receivable, net .............				7
8	Inventories for sale or use ..............				8
9	Prepaid expenses and deferred charges ............			148,497	9	259,281
10a	Land, buildings, and equipment: cost or other basis. Complete Part VI of Schedule D	10a	679,597
b	Less: accumulated depreciation. .....	10b	299,723	438,985	10c	379,874
11	Investments—publicly traded securities ..........			13,226,976	11	12,612,133
12	Investments—other securities. See Part IV, line 11 ......			20,444,755	12	22,125,431
13	Investments—program-related. See Part IV, line 11 ..				13
14	Intangible assets .........				14
15	Other assets. See Part IV, line 11 ...........			145,201	15	47,437
16	Total assets. Add lines 1 through 15 (must equal line 34)...			45,520,143	16	48,860,406
17	Accounts payable and accrued expenses .			358,280	17	324,146
18	Grants payable ..........			22,924,244	18	22,261,113
19	Deferred revenue ..........				19
20	Tax-exempt bond liabilities ..........				20
21	Escrow or custodial account liability. Complete Part IV of Schedule D..				21
22	Payables to current and former officers, directors, trustees, key employees, highest compensated employees, and disqualified
	persons. Complete Part II of Schedule L..........				22
23	Secured mortgages and notes payable to unrelated third parties ..				23
24	Unsecured notes and loans payable to unrelated third parties ....				24
25	Other liabilities. Complete Part X of Schedule D.....			390,563	25	418,623
26	Total liabilities. Add lines 17 through 25.....			23,673,087	26	23,003,882
	Organizations that follow SFAS 117, check here and complete lines 27 through 29, and lines 33 and 34.
27	Unrestricted net assets .....			13,996,529	27	18,490,451
28	Temporarily restricted net assets .....			6,069,989	28	5,500,397
29	Permanently restricted net assets .....			1,780,538	29	1,865,676
	Organizations that do not follow SFAS 117, check here and complete lines 30 through 34.
30	Capital stock or trust principal, or current funds .....				30
31	Paid-in or capital surplus, or land, building or equipment fund .....				31
32	Retained earnings, endowment, accumulated income, or other funds				32
33	Total net assets or fund balances .....			21,847,056	33	25,856,524
34	Total liabilities and net assets/fund balances .....			45,520,143	34	48,860,406

Form 990 (2010)

Page 12

Part XI

Reconcilliation of Net Assets

Check if Schedule O contains a response to any question in this Part XI . . . . . . . . . .

Total revenue (must equal Part VIII, column (A), line 12) . . .

15,562,148

Total expenses (must equal Part IX, column (A), line 25) . . . . .

15,587,799

Revenue less expenses. Subtract line 2 from line 1 . . . .

-25,651

Net assets or fund balances at beginning of year (must equal Part X, line 33, column (A)) . .

21,847,056

Other changes in net assets or fund balances (explain in Schedule O) . . . .

4,035,119

Net assets or fund balances at end of year. Combine lines 3, 4, and 5 (must equal Part X, line 33, column (B)) . . . . . .

25,856,524

Part XII

Financial Statements and Reporting

Check if Schedule O contains a response to any question in this Part XII . . . . . . . . . .

Yes

Accounting method used to prepare the Form 990: Cash Accrual Other
If the organization changed its method of accounting from a prior year or checked "Other," explain in
Schedule O.

Were the organization’s financial statements compiled or reviewed by an independent accountant?..

Were the organization’s financial statements audited by an independent accountant?........

Yes

If “Yes,” to 2a or 2b, does the organization have a committee that assumes responsibility for oversight of the audit, review, or compilation of its financial statements and selection of an independent accountant?
If the organization changed either its oversight process or selection process during the tax year, explain in Schedule O............................

Yes

If “Yes” to line 2a or 2b, check a box below to indicate whether the financial statements for the year were issued on a separate basis, consolidated basis, or both:

Separate basis Consolidated basis Both consolidated and separated basis

As a result of a federal award, was the organization required to undergo an audit or audits as set forth in the Single Audit Act and OMB Circular A-133? ................

If “Yes,” did the organization undergo the required audit or audits? If the organization did not undergo the required audit or audits, explain why in Schedule O and describe any steps taken to undergo such audits. ..

Form 990 (2010)

Additional Data

Software ID:
Software Version:

Form 990, Special Condition Description:

Special Condition Description

- TIN:

SCHEDULE A
(Form 990 or 990EZ)

Department of the Treasury
Internal Revenue Service

Public Charity Status and Public Support

Complete if the organization is a section 501(c)(3) organization or a section
4947(a)(1) nonexempt charitable trust.

Attach to Form 990 or Form 990-EZ. right arrow

See separate instructions.

OMB No. 1545-0047

2010

Open to Public
Inspection

Name of the organization

CANCER RESEARCH INSTITUTE

Employer identification number

13-1837442

Part I

Reason for Public Charity Status (All organizations must complete this part.) See instructions

The organization is not a private foundation because it is: (For lines 1 through 11, check only one box.)

A church, convention of churches, or association of churches. section 170(b)(1)(A)(i).

A school described in section 170(b)(1)(A)(ii). (Attach Schedule E.)

A hospital or a cooperative hospital service organization described in section 170(b)(1)(A)(iii).

A medical research organization operated in conjunction with a hospital described in section 170(b)(1)(A)(iii). Enter the hospital's name, city, and state:

An organization operated for the benefit of a college or university owned or operated by a governmental unit described in

section 170(b)(1)(A)(iv). (Complete Part II.)

A federal, state, or local government or governmental unit described in section 170(b)(1)(A)(v).

An organization that normally receives a substantial part of its support from a governmental unit or from the general public described in

section 170(b)(1)(A)(vi). (Complete Part II.)

A community trust described in section 170(b)(1)(A)(vi). (Complete Part II.)

An organization that normally receives: (1) more than 331/3% of its support from contributions, membership fees, and gross

receipts from activities related to its exempt functions—subject to certain exceptions, and (2) no more than 331/3% of

its support from gross investment income and unrelated business taxable income (less section 511 tax) from businesses

acquired by the organization after June 30, 1975. See section 509(a)(2). (Complete Part III.)

An organization organized and operated exclusively to test for public safety. Seesection 509(a)(4).

An organization organized and operated exclusively for the benefit of, to perform the functions of, or to carry out the purposes of one or more publicly supported organizations described in section 509(a)(1) or section 509(a)(2). See section 509(a)(3). Check the box that describes the type of supporting organization and complete lines 11e through 11h.

Type I

Type II

Type III - Functionally integrated

Type III - Other

By checking this box, I certify that the organization is not controlled directly or indirectly by one or more disqualified persons other than foundation managers and other than one or more publicly supported organizations described in section 509(a)(1) or section 509(a)(2).

If the organization received a written determination from the IRS that it is a Type I, Type II or Type III supporting organization, check this box ..................................................

Since August 17, 2006, has the organization accepted any gift or contribution from any of the
following persons?

(i) a person who directly or indirectly controls, either alone or together with persons described in (ii)

Yes

and (iii) below, the governing body of the the supported organization? ................

11g(i)

(ii) a family member of a person described in (i) above? ......................

11g(ii)

(iii) a 35% controlled entity of a person described in (i) or (ii) above? ................

11g(iii)

Provide the following information about the supported organization(s).

(i) Name of supported organization	(ii) EIN	(iv) Is the organization in col. (i) listed in your governing document?		(v) Did you notify the organization in col. (i) of your support?		(vi) Is the organization in col. (i) organized in the U.S.?		(vii) Amount of support?
(i) Name of supported organization	(ii) EIN	Yes	No	Yes	No	Yes	No	(vii) Amount of support?


Total

For Paperwork Reduction Act Notice, see the Instructions for Form 990.

Cat. No. 11285F

Schedule A (Form 990 or 990-EZ) 2010

Page 2

Part II

Support Schedule for Organizations Described in IRC 170(b)(1)(A)(iv) and 170(b)(1)(A)(vi)
(Complete only if you checked the box on line 5, 7, or 8 of Part I or if the organization failed to qualify under Part III. If the organization fails to qualify under the tests listed below, please complete Part III.)

Section A. Public Support

Calendar year(or fiscal year beginning in)		(a) 2006	(b) 2007	(c) 2008	(d) 2009	(e) 2010	(f) Total
1	Gifts, grants, contributions, and membership fees received. (Do not include any "unusual grants.") ....	12,559,539	11,022,177	11,769,264	13,374,848	14,808,431	63,534,259
2	Tax revenues levied for the organization's benefit and either paid to or expended on its behalf.......
3	The value of services or facilities furnished by a governmental unit to the organization without charge..
4	Total. Add lines 1 through 3..	12,559,539	11,022,177	11,769,264	13,374,848	14,808,431	63,534,259
5	The portion of total contributions by each person (other than a governmental unit or publicly supported organization) included on line 1 that exceeds 2% of the amount shown on line 11, column (f)..						6,032,152
6	Public Support. Subtract line 5 from line 4.						57,502,107

Section B. Total Support

Calendar year(or fiscal year beginning in)		(a) 2006	(b) 2007	(c) 2008	(d) 2009	(e) 2010	(f) Total
7	Amounts from line 4..	12,559,539	11,022,177	11,769,264	13,374,848	14,808,431	63,534,259
8	Gross income from interest, dividends, payments received on securities loans, rents, royalties and income from similar sources..	1,673,771	6,425,586	-604,133	306,591	751,440	8,553,255
9	Net income from unrelated business activities, whether or not the business is regularly carried on..
10	Other income. (Explain in Part IV.) Do not include gain or loss from the sale of capital assets..	1,000,000	8,387	-130,154	26,785	17,425	922,443
11	Total support (Add lines 7 through 10).						73,009,957

Gross receipts from related activities, etc. (See instructions.) ..................

First Five Years If the Form 990 is for the organization's first, second, third, fourth, or fifth tax year as a 501(c)(3) organization,
check this box and stop here.......................................... right arrow

Section C. Computation of Public Support Percentage

Public Support Percentage for 2010 (line 6 column (f) divided by line 11 column (f)) .........

78.759 %

Public Support Percentage for 2009 Schedule A, Part II, line 14 ...............

75.273 %

16a

33 1/3% support test—2010. If the organization did not check the box on line 13, and line 14 is 33 1/3% or more, check this box
and stop here. The organization qualifies as a publicly supported organization ...................... right arrow

33 1/3% support test—2009. If the organization did not check the box on line 13 or 16a, and line 15 is 33 1/3% or more, check this
box and stop here. The organization qualifies as a publicly supported organization ..................... right arrow

17a

10%-facts-and-circumstances test—2010. If the organization did not check a box on line 13, 16a, or 16b and line 14
is 10% or more, and if the organization meets the "facts and circumstances" test, check this box and stop here. Explain
in Part IV how the organization meets the "facts and circumstances" test. The organization qualifies as a publicly supported
organization .................................................. right arrow

10%-facts-and-circumstances test—2009. If the organization did not check a box on line 13, 16a, 16b, or 17a and line
15 is 10% or more, and if the organization meets the "facts and circumstances" test, check this box and stop here.
Explain in Part IV how the organization meets the "facts and circumstances" test. The organization qualifies as a publicly
supported organization .............................................. right arrow

Private Foundation If the organization did not check a box on line 13, 16a, 16b, 17a or 17b, check this box and see
instructions ................................................... right arrow

Schedule A (Form 990 or 990-EZ) 2010

Page 3

Part III

Support Schedule for Organizations Described in IRC 509(a)(2)
(Complete only if you checked the box on line 9 of Part I or if the organization failed to qualify under Part II. If the organization fails to qualify under the tests listed below, please complete Part II.)

Section A. Public Support

Calendar year(or fiscal year beginning in)		(a) 2006	(b) 2007	(c) 2008	(d) 2009	(e) 2010	(f) Total
1	Gifts, grants, contributions, and membership fees received. (Do not include any "unusual grants.") .
2	Gross receipts from admissions, merchandise sold or services performed, or facilities furnished in any activity that is related to the organization's tax-exempt purpose......
3	Gross receipts from activities that are not an unrelated trade or business under section 513..
4	Tax revenues levied for the organization's benefit and either paid to or expended on its behalf...
5	The value of services or facilities furnished by a governmental unit to the organization without charge..
6	Total. Add lines 1 through 5.
7a	Amounts included on lines 1, 2, and 3 received from disqualified persons...
b	Amounts included on lines 2 and 3 received from other than disqualified persons that exceed the greater of $5,000 or 1% of the amount on line 13 for the year.
c	Add lines 7a and 7b..
8	Public Support (Subtract line 7c from line 6.)

Section B. Total Support

Calendar year (or fiscal year beginning in)		(a) 2006	(b) 2007	(c) 2008	(d) 2009	(e) 2010	(f) Total
9	Amounts from line 6...
10a	Gross income from interest, dividends, payments received on securities loans, rents, royalties and income from similar sources..
b	Unrelated business taxable income (less section 511 taxes) from businesses acquired after June 30, 1975.
c	Add lines 10a and 10b.
11	Net income from unrelated business activities not included in line 10b, whether or not the business is regularly carried on.
12	Other income. Do not include gain or loss from the sale of capital assets (Explain in Part IV.)
13	Total support (Add lines 9, 10c, 11 and 12.).

Section C. Computation of Public Support Percentage

Public Support Percentage for 2010 (line 8 column (f) divided by line 13 column (f)) .........

Public support percentage from 2009 Schedule A, Part III, line 15 ...............

Section D. Computation of Investment Income Percentage

Investment income percentage for 2010 (line 10c column (f) divided by line 13 column (f)) ......

Investment income percentage from 2009 Schedule A, Part III, line 17 .............

19a

33 1/3% support tests—2010. If the organization did not check the box on line 14, and line 15 is more than 33 1/3% and line 17 is not more than 33 1/3%, check this box and stop here. The organization qualifies as a publicly supported organization .......... right arrow

33 1/3% support tests—2009. If the organization did not check a box on line 14 or line 19a, and line 16 is more than 33 1/3% and line 18 is not more than 33 1/3%, check this box and stop here. The organization qualifies as a publicly supported organization .... right arrow

Private Foundation If the organization did not check a box on line 14, 19a or 19b, check this box and see instructions ..... right arrow

Schedule A (Form 990 or 990-EZ) 2010

Page 4

Part IV

Supplemental Information. Supplemental Information. Complete this part to provide the explanation required by Part II, line 10; Part II, line 17a or 17b; or Part III, line 12. Also complete this part for any additional information. (See instructions).

Facts And Circumstances Test

Explanation

Schedule A (Form 990 or 990-EZ) 2010

Additional Data

Software ID:
Software Version:

- TIN:

Schedule B
(Form 990, 990-EZ,
or 990-PF)

Department of the Treasury
Internal Revenue Service

Schedule of Contributors

Attach to Form 990, 990-EZ, or 990-PF.

OMB No. 1545-0047

2010

Name of organization

CANCER RESEARCH INSTITUTE

Employer identification number

13-1837442

Organization type (check one):

Filers of:

Section:

Form 990 or 990-EZ

501(c)( ) (enter number) organization

4947(a)(1) nonexempt charitable trust not treated as a private foundation

527 political organization

Form 990-PF

501(c)(3) exempt private foundation

4947(a)(1) nonexempt charitable trust treated as a private foundation

501(c)(3) taxable private foundation

Check if your organization is covered by the General Rule or a Special Rule.
Note. Only a section 501(c)(7), (8), or (10) organization can check boxes for both the General Rule and a Special Rule. See instructions.

General Rule

For an organization filing Form 990, 990-EZ, or 990-PF that received, during the year, $5,000 or more (in money or
property) from any one contributor. Complete Parts I and II.

Special Rules

For a section 501(c)(3) organization filing Form 990 or 990-EZ, that met the 33¹/3% support test of the regulations
under sections 509(a)(1) and 170(b)(1)(A)(vi), and received from any one contributor, during the year, a contribution of the
greater of (1) $5,000 or (2) 2% of the amount on (i) Form 990, Part VIII, line 1h, or (ii) Form 990-EZ, line 1. Complete Parts I and II.

For a section 501(c)(7), (8), or (10) organization filing Form 990, or 990-EZ, that received from any one contributor,
during the year, aggregate contributions of more than $1,000 for use exclusively for religious, charitable,
scientific, literary, or educational purposes, or the prevention of cruelty to children or animals. Complete Parts I, II, and
III.

For a section 501(c)(7), (8), or (10) organization filing Form 990, or 990-EZ, that received from any one contributor,
during the year, contributions for use exclusively for religious, charitable, etc., purposes, but these contributions did
not aggregate to more than $1,000. If this box is checked, enter here the total contributions that were received during
the year for an exclusively religious, charitable, etc., purpose. Do not complete any of the parts unless the General Rule
applies to this organization because it received nonexclusively religious, charitable, etc., contributions of $5,000 or more
during the year. ......................... Arrow Bullet

Caution. An Organization that is not covered by the General Rule and/or the Special Rules does not file Schedule B (Form 990,
990-EZ, or 990-PF), but it must answer “No” on Part IV, line 2 of its Form 990, or check the box in the heading of its
Form 990-EZ, or on line 2 of its Form 990-PF, to certify that it does not meet the filing requirements of Schedule B (Form 990,
990-EZ, or 990-PF).

For Paperwork Reduction Act Notice, see the Instructions
for Form 990, 990-EZ, or 990-PF.

Cat. No. 30613XSchedule B (Form 990, 990-EZ, or 990-PF) (2010)

Name of organization CANCER RESEARCH INSTITUTE
Schedule B (Form 990, 990-EZ, or 990-PF) (2010) Page 1 of 1 of Part I
Part I	Contributors (see Instructions)
(a) No.	(b) Name, address, and ZIP + 4	(c) Aggregate contributions	(d) Type of contribution
RESTRICTED	RESTRICTED RESTRICTED RESTRICTED RESTRICTED, RESTRICTED RESTRICTED	$RESTRICTED	Person Payroll Noncash (Complete Part II if there is a noncash contribution.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Aggregate contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II if there is a noncash contribution.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Aggregate contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II if there is a noncash contribution.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Aggregate contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II if there is a noncash contribution.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Aggregate contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II if there is a noncash contribution.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Aggregate contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II if there is a noncash contribution.)
Schedule B (Form 990, 990-EZ, or 990-PF) (2010)

Name of organization CANCER RESEARCH INSTITUTE
Schedule B (Form 990, 990-EZ, or 990-PF) (2010) Page 1 of 1 of Part II
Part II	Noncash Property (see Instructions)
(a) No. from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (see instructions)	(d) Date received
		$
(a) No. from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (see instructions)	(d) Date received
		$
(a) No. from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (see instructions)	(d) Date received
		$
(a) No. from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (see instructions)	(d) Date received
		$
(a) No. from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (see instructions)	(d) Date received
		$
(a) No. from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (see instructions)	(d) Date received
		$
Schedule B (Form 990, 990-EZ, or 990-PF) (2010)

Schedule B (Form 990, 990-EZ, or 990-PF) (2010)

Page 1 of 1 of Part III

Name of organization
CANCER RESEARCH INSTITUTE

Employer identification number

13-1837442

Part III

Exclusively religious, charitable, etc., individual contributions to section 501(c)(7), (8), or (10) organizations
aggregating more than $1,000 for the year. (Complete columns (a) through (e) and the following line entry.)
For organizations completing Part III, enter the total of exclusively religious, charitable, etc.,
contributions of $1,000 or less for the year. (Enter this information once. See instructions.) Arrow Bullet

(a) No.
from
Part I

(b)
Purpose of gift

(d)
Description of how gift is held

(e) Transfer of gift
Transferee's name, address, and ZIP 4	Relationship of transferor to transferee

(a) No.
from
Part I

(b)
Purpose of gift

(d)
Description of how gift is held

(e) Transfer of gift
Transferee's name, address, and ZIP 4	Relationship of transferor to transferee

(a) No.
from
Part I

(b)
Purpose of gift

(d)
Description of how gift is held

(e) Transfer of gift
Transferee's name, address, and ZIP 4	Relationship of transferor to transferee

(a) No.
from
Part I

(b)
Purpose of gift

(d)
Description of how gift is held

(e) Transfer of gift
Transferee's name, address, and ZIP 4	Relationship of transferor to transferee

Schedule B (Form 990, 990-EZ, or 990-PF) (2010)

Additional Data

Software ID:
Software Version:

- TIN:

SCHEDULE D
(Form 990)

Department of the Treasury
Internal Revenue Service

Supplemental Financial Statements

Complete if the organization answered "Yes," to Form 990,
Part IV, line 6, 7, 8, 9, 10, 11, or 12.
SchDMd Bullet

Attach to Form 990. SchDMd Bullet

See separate instructions.

OMB No. 1545-0047

2010

Open to Public Inspection

Name of the organization

CANCER RESEARCH INSTITUTE

Employer identification number

13-1837442

Part I

Organizations Maintaining Donor Advised Funds or Other Similar Funds or Accounts. Complete if the organization answered "Yes" to Form 990, Part IV, line 6.

		(a) Donor advised funds	(b) Funds and other accounts
1	Total number at end of year .......
2	Aggregate contributions to (during year) ...
3	Aggregate grants from (during year) ...
4	Aggregate value at end of year .......

Did the organization inform all donors and donor advisors in writing that the assets held in donor advised
funds are the organization's property, subject to the organization's exclusive legal control? ............

Yes No

Did the organization inform all grantees, donors, and donor advisors in writing that grant funds may be
used only for charitable purposes and not for the benefit of the donor or donor advisor, or for any other purpose conferring impermissible private benefit. ...................................

Yes No

Part II

Conservation Easements. Complete if the organization answered "Yes" to Form 990, Part IV, line 7.

Purpose(s) of conservation easements held by the organization (check all that apply).

Preservation of land for public use (e.g., recreation or pleasure) Preservation of an historically importantly land area

Protection of natural habitat Preservation of a certified historic structure

Preservation of open space

Complete lines 2a–2d if the organization held a qualified conservation contribution in the form of a conservation easement on the last day of the tax year.


a	Total number of conservation easements .......................	2a
b	Total acreage restricted by conservation easements ..................	2b
c	Number of conservation easements on a certified historic structure included in (a) .....	2c
d	Number of conservation easements included in (c) acquired after 8/17/06 ........	2d

Number of conservation easements modified, transferred, released, extinguished, or terminated by the organization during
the taxable year SchDMd Bullet

Number of states where property subject to conservation easement is located SchDMd Bullet

Does the organization have a written policy regarding the periodic monitoring, inspection, handling of violations, and
enforcement of the conservation easements it holds? .............................

Yes No

Staff and volunteer hours devoted to monitoring, inspecting and enforcing conservation easements during the year SchDMd Bullet

Amount of expenses incurred in monitoring, inspecting, and enforcing conservation easements during the year SchDMd Bullet

Does each conservation easement reported on line 2(d) above satisfy the requirements of section
170(h)(4)(B)(i) and 170(h)(4)(B)(ii)? ....................................

Yes No

In Part XIV, describe how the organization reports conservation easements in its revenue and expense statement, and
balance sheet, and include, if applicable, the text of the footnote to the organization’s financial statements that describes
the organization’s accounting for conservation easements.

Part III

Organizations Maintaining Collections of Art, Historical Treasures, or Other Similar Assets.
Complete if the organization answered "Yes" to Form 990, Part IV, line 8.

If the organization elected, as permitted under SFAS 116, not to report in its revenue statement and balance sheet works of
art, historical treasures, or other similar assets held for public exhibition, education or research in furtherance of public service,
provide, in Part XIV, the text of the footnote to its financial statements that describes these items.

If the organization elected, as permitted under SFAS 116, to report in its revenue statement and balance sheet works of art,
historical treasures, or other similar assets held for public exhibition, education, or research in furtherance of public service,
provide the following amounts relating to these items:

(i)

Revenues included in Form 990, Part VIII, line 1 ........................ SchDMd Bullet

(ii)

Assets included in Form 990, Part X .............................. SchDMd Bullet

If the organization received or held works of art, historical treasures, or other similar assets for financial gain, provide the
following amounts required to be reported under SFAS 116 relating to these items:

Revenues included in Form 990, Part VIII, line 1 .......................... SchDMd Bullet

Assets included in Form 990, Part X ............................... SchDMd Bullet

For Privacy Act and Paperwork Reduction Act Notice, see the Intructions for Form 990

Cat. No. 52283D

Schedule D (Form 990) 2010

Page 2

Part III

Organizations Maintaining Collections of Art, Historical Treasures, or Other Similar Assets (continued)

Using the organization’s accession and other records, check any of the following that are a significant use of its collection
items (check all that apply):

Public exhibition

Loan or exchange programs

Scholarly research

Other

Preservation for future generations

Provide a description of the organization’s collections and explain how they further the organization’s exempt purpose in
Part XIV.

During the year, did the organization solicit or receive donations of art, historical treasures or other similar
assets to be sold to raise funds rather than to be maintained as part of the organization’s collection?........

Yes No

Part IV

Escrow and Custodial Arrangements. Complete if the organization answered "Yes" to Form 990,
Part IV, line 9, or reported an amount on Form 990, Part X, line 21.

Is the organization an agent, trustee, custodian or other intermediary for contributions or other assets not
included on Form 990, Part X? ....................................

Yes No

If "Yes," explain the arrangement in Part XIV and complete the following table:


c	Beginning balance .................................	1c
d	Additions during the year ..............................	1d
e	Distributions during the year .............................	1e
f	Ending balance ...................................	1f

Did the organization include an amount on Form 990, Part X, line 21? .....................

Yes No

If “Yes,” explain the arrangement in Part XIV.

Part V

Endowment Funds. Complete if the organization answered "Yes" to Form 990, Part IV, line 10.

		(a)Current Year	(b)Prior Year	(c)Two Years Back
1a	Beginning of year balance ....	3,863,839	3,639,179	3,825,382
b	Contributions ........	65,275	119,112	76,000
c	Investment earnings or losses ...		205,548	-162,203
d	Grants or scholarships .....
e	Other expenditures for facilities and programs ........	50,000	100,000	100,000
f	Administrative expenses ....
g	End of year balance ......	3,879,114	3,863,839	3,639,179

Provide the estimated percentage of the year end balance held as:

Board designated or quasi-endowment: SchDMd Bullet

56.000 %

Permanent endowment: SchDMd Bullet

44.000 %

Term endowment: SchDMd Bullet

Are there endowment funds not in the possession of the organization that are held and administered for the
organization by:

Yes

(i) unrelated organizations ........................

3a(i)

(ii) related organizations ........................

3a(ii)

If "Yes" to 3a(ii), are the related organizations listed as required on Schedule R? .........

Describe in Part XIV the intended uses of the organization's endowment funds.

Part VI

InvestmentsLand, Buildings, and Equipment. See Form 990, Part X, line 10.

Description of investment		(b)Cost or other basis (other)	(c) Accumulated depreciation	(d) Book value
1a	Land .................
b	Buildings ................
c	Leasehold improvements ............	159,795	56,417	103,378
d	Equipment ................	507,737	243,306	264,431
e	Other .................
Total. Add lines 1a-1e. (Column (d) should equal Form 990, Part X, column (B), line 10(c).)........				367,809

Schedule D (Form 990) 2010

Page 3

Part VII

InvestmentsOther Securities. See Form 990, Part X, line 12.

(a) Description of security or category (including name of security)	(b)Book value	(c) Method of valuation: Cost or end-of-year market value
(1)Financial derivatives
(2)Closely-held equity interests
(3)Other (A) LIMITED PARTNERSHIPS AND OTHER	22,125,431	F








Total. (Column (b) should equal Form 990, Part X, col.(B) line 12.)	22,125,431

Part VIII

InvestmentsProgram Related. See Form 990, Part X, line 13.

(a) Description of investment type		(b) Book value	(c) Method of valuation: Cost or end-of-year market value









Total. (Column (b) should equal Form 990, Part X, col.(B) line 13.)

Part IX

Other Assets. See Form 990, Part X, line 15.

(a) Description				(b) Book value









Total. (Column (b) should equal Form 990, Part X, col.(B) line 15.)...........

Part X

Other Liabilities. See Form 990, Part X, line 25.

1.(a) Description of Liability		(b) Amount
Federal Income Taxes		0
REFUNDABLE DEPOSIT		146,250
DEFERRED RENT		272,373







Total. (Column (b) should equal Form 990, Part X, col.(B) line 25.)		418,623
2. Fin 48 (ASC 740) Footnote. In Part XIV, provide the text of the footnote to the organization's financial statements that reports the organization's liability for uncertain tax positions under FIN 48 (ASC740).

Schedule D (Form 990) 2010

Page 4

Part XI Reconciliation of Change in Net Assets from Form 990 to Financial Statements
1	Total revenue (Form 990, Part VIII, column (A), line 12) ....................	1	15,562,148
2	Total expenses (Form 990, Part IX, column (A), line 25) .....................	2	15,587,799
3	Excess or (deficit) for the year. Subtract line 2 from line 1 .............	3	-25,651
4	Net unrealized gains (losses) on investments ..........................	4	4,035,119
5	Donated services and use of facilities .............................	5
6	Investment expenses ...................................	6
7	Prior period adjustments ..................................	7
8	Other (Describe in Part XIV) .................................	8
9	Total adjustments (net). Add lines 4 - 8 .............................	9	4,035,119
10	Excess or (deficit) for the year per financial statements. Combine lines 3 and 9 .........	10	4,009,468

Part XII Reconciliation of Revenue per Audited Financial Statements With Revenue per Return
1	Total revenue, gains, and other support per audited financial statements .......			1	20,198,161
2	Amounts included on line 1 but not on Form 990, Part VIII, line 12:
a	Net unrealized gains on investments ..........	2a	4,035,119
b	Donated services and use of facilities .........	2b	717,227
c	Recoveries of prior year grants ...........	2c
d	Other (Describe in Part XIV): ............	2d
e	Add lines 2a through 2d .....................			2e	4,752,346
3	Subtract line 2e from line 1.....................			3	15,445,815
4	Amounts included on Form 990, Part VIII, line 12, but not on line 1:
a	Investment expenses not included on Form 990, Part VIII, line 7b .	4a	116,333
b	Other (Describe in Part XIV): ...........	4b
c	Add lines 4a and 4b.......................			4c	116,333
5	Total Revenue. Add lines 3 and 4c. (This should equal Form 990, Part I, line 12.) ......			5	15,562,148

Part XIII Reconciliation of Expenses per Audited Financial Statements With Expenses per Return
1	Total expenses and losses per audited financial statements .............			1	16,188,693
2	Amounts included on line 1 but not on Form 990, Part IX, line 25:
a	Donated services and use of facilities ..........	2a	717,227
b	Prior year adjustments ..............	2b
c	Other losses ................	2c
d	Other (Describe in Part XIV): ............	2d
e	Add lines 2a through 2d......................			2e	717,227
3	Subtract line 2e from line 1.....................			3	15,471,466
4	Amounts included on Form 990, Part IX, line 25, but not on line 1:
a	Investment expenses not included on Form 990, Part VIII, line 7b ..	4a	116,333
b	Other (Describe in Part XIV): ............	4b
c	Add lines 4a and 4b.......................			4c	116,333
5	Total expenses. Add lines 3 and 4c. (This should equal Form 990, Part I, line 18.) ......			5	15,587,799

Part XIV

Supplemental Information

Complete this part to provide the descriptions required for Part II, lines 3, 5, and 9; Part III, lines 1a and 4; Part lV, lines 1b and 2b;
Part V, line 4; Part X; Part XI, line 8; Part XII, lines 2d and 4b; and Part XIII, lines 2d and 4b. Also complete this part to provide any additional information.

Identifier	Return Reference	Explanation
SCHEDULE D PART X LINE 2	INCOME TAX UNCERTAINTIES	THE INSTITUTE IS SUBJECT TO THE PROVISIONS OF ASC 740-10-05 RELATING TO ACCOUNTING AND REPORTING FOR UNCERTAINTY IN INCOME TAXES. BECAUSE OF THE INSTITUTE'S GENERAL TAX-EXEMPT STATUS, ASC 740-10-05 HAS NOT HAD, AND IS NOT ANTICIPATED TO HAVE, A MATERIAL IMPACT ON THE INSTITUTE'S FINANCIAL STATEMENTS.
SCHEDULE D PART V LINE 4	USE OF ENODWMENT FUNDS	THE INSTITUTE'S ENDOWMENT CONSIST OF THREE DONOR RESTRICTED FUNDS ESTABLISHED TO SUPPORT FELLOWSHIP PROGRAMS.

Schedule D (Form 990) 2010

Additional Data

Software ID:
Software Version:

- TIN:

SCHEDULE F
(Form 990)

Department of the Treasury
Internal Revenue Service

Statement of Activities Outside the United States

Complete if the organization answered "Yes" to Form 990,
Part IV, line 14b, 15, or 16.
Right pointing arrow large image

Attach to Form 990. Right pointing arrow large image

See separate instructions.

OMB No. 1545-0047

2010

Open to Public Inspection

Name of the organization
CANCER RESEARCH INSTITUTE

Employer identification number

13-1837442

Part I

General Information on Activities Outside the United States. Complete if the organization answered
“Yes” to Form 990, Part IV, line 14b.

For grantmakers. Does the organization maintain records to substantiate the amount of the grants or

assistance, the grantees' eligibility for the grants or assistance, and the selection criteria used to award

the grants or assistance? ...................................

Yes

For grantmakers. Describe in Part V the organization’s procedures for monitoring the use of grant funds outside the
United States.

Activites per Region. (Use Part V if additional space is needed.)

(a) Region		(b) Number of offices in the region	(c) Number of employees or agents in region or independent contractors	(d) Activities conducted in region (by type) (e.g., fundraising, program services, investments, grants to recipients located in the region)	(e) If activity listed in (d) is a program service, describe specific type of service(s) in region	(f) Total expenditures for region/investments in region
	Central America and the Caribbean	0	0	Investments
	Sub-Saharan Africa	0	0	Investments
	Europe (Including Iceland and Greenland)	0	0	Investments
	Europe (Including Iceland and Greenland)	0	0	Program Services	GRANT MAKING	1,190,000
	East Asia and the Pacific	0	0	Program Services	GRANT MAKING	250,000












3a	Sub-total .....	0	0			1,440,000
b	Total from continuation sheets to Part I ...
c	Totals (add lines 3a and 3b)	0	0			1,440,000

For Privacy Act and Paperwork Reduction Act Notice, see the Instructions for Form 990.Cat. No. 50082W Schedule F (Form 990) 2010

Schedule F (Form 990) 2010

Page 2

Part II

Grants and Other Assistance to Organizations or Entities Outside the United States. Complete if the organization answered "Yes" to Form 990,

Part IV, line 15, for any recipient who received more than $5,000. Check this box if no one recipient received more than $5,000 ........ MediumBullet

Use Part V if additional space is needed.

(c) Region	(d) Purpose of grant	(e) Amount of cash grant	(f) Manner of cash disbursement
Europe/Iceland/Greenland	STUDIES ON EBV AND HHV-8, ONCOGENES AND TUMOR SUPP THE ROLE OF AIRE IN THEIR FUNCTION.	40,000	CHECK
East Asia/Pacific	XAGE: A VACCINE TARGET FOR LUNG CANCER TYROSINE KINASE FAMILY	50,000	CHECK
Europe/Iceland/Greenland	ACADEMY OF CANCER IMMUNOLOGY'S ONLINE JOURNAL, CAN THE NEMATODE C ELEGANS.	50,000	CHECK
East Asia/Pacific	CVC JAPAN IN PEYER'S PATCHES	800,000	CHECK
Europe/Iceland/Greenland	MECHANISMS UNDERPINNING THE FUNCTION OF REGULARY A APPROACHES TO INTERROGATE DYNAMICS AND FEEDBACK IN T CELL SIGNALLING.	200,000	CHECK
Europe/Iceland/Greenland	STUDIES ON EPSTEIN-BARR VIRUS AND KAPOSI SARCOMA HERPES VIRUS, ONCOGENES AND TUMOR SUPPRESSOR GENES, TUMOR IMMUNOLOGY, AND INHIBITION OF TUMOR CELL GROWTH BY STROMA	300,000	CHECK

Enter total number of recipient organizations listed above that are recognized as charities by the foreign country, recognized as tax-exempt by the IRS, or for which the grantee or counsel has provided a section 501(c)(3) equivalency letter ..... MediumBullet

Enter total number of other organizations or entities ........................ MediumBullet

Schedule F (Form 990) 2010

Schedule F (Form 990) 2010Page 3

Part III

Grants and Other Assistance to Individuals Outside the United States. Complete if the organization answered "Yes" to Form 990, Part IV, line 16.

Use Part V if additional space is needed.

(a) Type of grant or assistance		(b) Region	(c) Number of recipients	(d) Amount of cash grant	(e) Manner of cash disbursement	(f) Amount of non-cash assistance	(g) Description of non-cash assistance	(h) Method of valuation (book, FMV, appraisal, other)

Schedule F (Form 990) 2010

Page 4

Part IV

Foreign Forms

Schedule F (Form 990) 2010

Page 5

Part V

Supplemental Information
Complete this part to provide the information (see instructions) required in Part I, line 2, and any additional information.

Identifier	ReturnReference	Explanation
Monitoring Grants	Schedule F Part I	Cancer Research Institute Inc requires grant recipients to complete a periodic status report prior to grant disbursement.

Schedule F (Form 990) 2010

Additional Data

Software ID:
Software Version:

- TIN:

SCHEDULE G
(Form 990 or 990-EZ)

Department of the Treasury
Internal Revenue Service

Supplemental Information Regarding
Fundraising or Gaming Activities

Complete if the organization answered "Yes" to Form 990, Part IV, lines 17, 18, or 19,
or if the organization entered more than $15,000 on Form 990-EZ, line 6a.
right arrow

Attach to Form 990 or Form 990-EZ. right arrow

See separate instructions.

OMB No. 1545-0047

2010

Open to Public Inspection

Name of the organization
CANCER RESEARCH INSTITUTE

Employer identification number

13-1837442

Part I

Fundraising Activities. Complete if the organization answered "Yes" to Form 990, Part IV, line 17.

Indicate whether the organization raised funds through any of the following activities. Check all that apply.

a	Mail solicitations	e	Solicitation of non-government grants
b	Internet and e-mail solicitations	f	Solicitation of government grants
c	Phone solicitations	g	Special fundraising events
d	In-person solicitations

Did the organization have a written or oral agreement with any individual (including officers, directors, trustees

or key employees listed in Form 990, Part VII) or entity in connection with professional fundraising services?

Yes

If “Yes,” list the ten highest paid individuals or entities (fundraisers) pursuant to agreements under which the fundraiser is
to be compensated at least $5,000 by the organization. Form 990-EZ filers are not required to complete this table.

(i) Name and address of individual or entity (fundraiser)	(ii) Activity	(iii) Did fundraiser have custody or control of contributions?		(iv) Gross receipts from activity	(v) Amount paid to (or retained by) fundraiser listed in col. (i)	(vi) Amount paid to (or retained by) organization
	(ii) Activity	Yes	No	(iv) Gross receipts from activity		(vi) Amount paid to (or retained by) organization
LW Robbins Associates 201 Summer Street PO Box 5838 Holliston, MA017465838	FR Counsel		No	114,214	85,915	28,299
Total .................				114,214	85,915	28,299

List all states in which the organization is registered or licensed to solicit funds or has been notified it is exempt from registration or licensing.

AZ, CA, CO, CT, DC, FL, GA, HI, IL, IA, MD, MI, MN, MS, MO, MT, NE, NH, NJ, NM, NY, NC, ND, OH, OR, PA, RI, SC, TN, UT, VA, WA, WV

For Privacy Act and Paperwork Reduction Act Notice, see the Instructions for Form 990.

Cat. No. 50083H

Schedule G (Form 990 or 990-EZ) 2010

Page 2

Part II

Fundraising Events. Complete if the organization answered "Yes" to Form 990, Part IV, line 18, or reported more than $15,000 on Form 990-EZ, line 6a. List events with gross receipts greater than $5,000.

		(a) Event #1 THROUGH THE KIT (event type)	(b) Event #2 GOLF OUTING (event type)	(c) Other Events 6 (total number)	(d) Total Events (Add col. (a) through col. (c))
1	Gross receipts . . .	669,306	119,185	144,063	932,554
2	Less: Charitable contributions . . .	574,649	65,340	113,150	753,139
3	Gross income (line 1 minus line 2) . . .	94,657	53,845	30,913	179,415
4	Cash prizes . . .
5	Non-cash prizes . .
6	Rent/facility costs . .
7	Food and beverages . .
8	Entertainment . . .
9	Other direct expenses .	94,657	53,845	30,913	179,415
10	Direct expense summary. Add lines 4 through 9 in column (d) ...........				179,415
11	Net income summary. Combine lines 3 and 10 in column (d)............

Part III

Gaming. Complete if the organization answered "Yes" to Form 990, Part IV, line 19, or reported more than $15,000 on Form 990-EZ, line 6a.

(a) Bingo

(b) Pull tabs/Instant
bingo/progressive bingo

(c) Other gaming

(d) Total gaming (Add col. (a) through col. (c))

Gross revenue . . . .

Cash prizes . . . .

Non-cash prizes . . .

Rent/facility costs . . .

Other direct expenses . .

Volunteer labor . . .

	Yes
	No

	Yes
	No

	Yes
	No

Direct expense summary. Add lines 2 through 5 in column (d) ........... right arrow

Net gaming income summary. Combine lines 1 and 7 in column (d) .......... right arrow

Enter the state(s) in which the organization operates gaming activities:

Is the organization licensed to operate gaming activities in each of these states? ............

YesNo

If "No," Explain:

10a

Were any of the organization's gaming licenses revoked, suspended or terminated during the tax year? .....

YesNo

If "Yes," Explain:

Does the organization operate gaming activities with nonmembers? .................

YesNo

Is the organization a grantor, beneficiary or trustee of a trust or a member of a partnership or other entity

formed to administer charitable gaming? ...........................

YesNo

Schedule G (Form 990 or 990-EZ) 2010

Page 3

Indicate the percentage of gaming activity operated in:

The organization's facility ......................

13a

An outside facility ........................

13b

Provide the name and address of the person who prepares the organization's gaming/special events books and records:

Name

Address

15a

Does the organization have a contract with a third party from whom the organization receives gaming

revenue? ......................................

YesNo

If "Yes," enter the amount of gaming revenue received by the organization right arrow

$ and the

amount of gaming revenue retained by the third party right arrow

$ .

If "Yes," enter name and address:

Name

Address

Gaming manager information:

Name

Gaming manager compensation right arrow

Description of services provided right arrow

Director/officer Employee Independent contractor

Mandatory distributions:

Is the organization required under state law to make charitable distributions from the gaming proceeds to

retain the state gaming license? ............................

YesNo

Enter the amount of distributions required under state law distributed to other exempt organizations or spent

in the organization's own exempt activities during the tax year right arrow

Part IV

Complete this part to provide additional information for responses to quuestion on Schedule G (see instructions.)

Identifier	ReturnReference	Explanation

Schedule G (Form 990 or 990-EZ) 2010

Additional Data

Software ID:
Software Version:

- TIN:

Schedule I
(Form 990)

Department of the Treasury
Internal Revenue Service

Grants and Other Assistance to Organizations,
Governments and Individuals in the United States

Complete if the organization answered "Yes," to Form 990, Part IV, line 21 or 22.
lBullet

Attach to Form 990

OMB No. 1545-0047

2010

Open to Public
Inspection

Name of the organization
CANCER RESEARCH INSTITUTE

Employer identification number
13-1837442

Part I

General Information on Grants and Assistance

Does the organization maintain records to substantiate the amount of the grants or assistance, the grantees' eligibility for the grants or assistance, and
the selection criteria used to award the grants or assistance? ....................................

Yes No

Describe in Part IV the organization's procedures for monitoring the use of grant funds in the United States.

Part II

Grants and Other Assistance to Governments and Organizations in the United States. Complete if the organization answered "Yes" to
Form 990, Part IV, line 21 for any recipient that received more than $5,000. Check this box if no one recipient received more than $5,000. Use
Part IV and Schedule I-1 (Form 990) if additional space is needed ......................... lBullet

(a) Name and address of organization or government	(b) EIN	(c) IRC Code section if applicable	(d) Amount of cash grant	(h) Purpose of grant or assistance
(1) CALIFORNIA INSTITUTE OF TECHNOLOGY1200 E CALIFORNIA BLVD PASADENA,CA91125	95-1643307	501(C)(3)	145,500	A MODEL SYSTEM TO INVESTIGATE ANTIBODY BIPOLAR BRIDGING MEDIATED BY gE-gI, A HERPES VIRUS Fc RECEPTOR
(2) CHILDREN'S HOSPITAL BOSTON300 LONGWOOD AVENUE BOSTON,MA02115	10-4277444	501(C)(3)	145,500	ROLE OF COFACTORS IN TARGETING ACTIVATION-INDUCED IMMUNOTHERAPY OF EOC GENES, TUMOR IMMUNOLOGY, AND INHIBITION OF TUMOR CELL GROWTH BY STROMA
(3) DANA-FARBER CANCER INSTITUTE44 BINNEY STREET BOSTON,MA02115	10-4277444	501(C)(3)	200,000	IDENTIFICATION OF NOVEL MOLECULAR CIRCUITS THAT LI IMMUNOTHERAPY OF EOC
(4) EMORY UNIVERSITY1510 CLIFTON ROAD ATLANTA,GA30322	04-2263040	501(C)(3)	145,500	ROLE OF DENDRITIC CELLS IN T CELL DYSFUNCTION DURI IMMUNOTHERAPY OF EOC
(5) HARVARD MEDICAL SCHOOL25 SHATTUCK STREET BOSTON,MA02115	58-0566256	501(C)(3)	225,000	PREDOC PROGRAM
(6) JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE733 NORTH BROADWAY BALTIMORE,MD21205	04-2103580	501(C)(3)	225,000	PREDOC PROGRAM CD3 AND CD28 CYTOPLASMIC TAIL FROM THE PLASMA MEMBRANE
(7) JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE733 NORTH BROADWAY BALTIMORE,MD21205	52-0595110	501(C)(3)	145,500	THE ROLE OF HIF-1 ADAPTIVE T CELL RESPONSES TO CAN COLORECTAL CANCER. MEMBRANE
(8) LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY9420 ATHENA CIRCLE LA JOLLA,CA92037	52-0595110	501(C)(3)	145,500	DISSECTING THE ROLE OF 5 HYDROXYMETHYLCYTOSINE IN RECOGNITION AND INHIBITION OF HUMAN PAILLOMAVIRUS.
(9) MEMORIAL SLOAN KETTERING CANCER CENTER1275 YORK AVENUE NEW YORK,NY10065	33-0328688	501(C)(3)	145,500	ROLE OF CONSERVED NON-CODING ELEMENTS OF FOXP3 IN MICROBIOTA IN COLORECTAL CANCER. PAILLOMAVIRUS.
(10) MEMORIAL SLOAN KETTERING CANCER CENTER1275 YORK AVENUE NEW YORK,NY10065	13-1624182	501(C)(3)	145,500	FUNCTIONAL CHARACTERIZATION OF THE NEW B7 FAMILY M STRAND BREAK REPAIR AND LYMPHOCYTE DEVELOPMENT.
(11) MEMORIAL SLOAN KETTERING CANCER CENTER1275 YORK AVENUE NEW YORK,NY10065	13-1624182	501(C)(3)	50,000	THE STUDY OF HEMATOPOIETIC STEM CELLS AND PREGENIT SUPPRESSOR GENES, TUMOR IMMUNOLOGY CYTOTOXIC DRUG SENSITIVITY AND INHIBITION OF TUMOR CELL GROWTH BY STROMA CELLS
(12) MEMORIAL SLOAN KETTERING CANCER CENTER1275 YORK AVENUE NEW YORK,NY10065	13-1624182	501(C)(3)	20,000	NATURAL KILLER CELL RESPONSES AGAINST CANCER AND I SUPPRESSOR GENES TUMOR IMMUNOLOGY CYTOTOXIC DRUG SENSITIVITY AND INHIBITION OF TUMOR CELL GROWTH BY STROMA CELLS.
(13) MEMORIAL SLOAN KETTERING CANCER CENTER1275 YORK AVENUE NEW YORK,NY10065	13-1624182	501(C)(3)	300,000	CVC CORE LABORATORY FUNDING SUPPRESSOR GENES TUMOR IMMUNOLOGY CYTOTOXIC DRUG SENSITIVITY AND INHIBITION OF TUMOR CELL GROWTH BY STROMA CELLS.
(14) MEMORIAL SLOAN KETTERING CANCER CENTER1275 YORK AVENUE NEW YORK,NY10065	13-1624182	501(C)(3)	2,000,000	CVAF OX40 MELANOMA TRIAL PORE FORMING PROTEIN ORAI1
(15) NEW YORK UNIVERSITY MEDICAL CENTER550 FIRST AVENUE NEW YORK,NY10016	13-1624182	501(C)(3)	95,000	THE ROLE OF ATM AND RAG IN MAINTAINING GENOME STAB NOVEL EPIGENETIC AND TRANSCRIPTIONAL REGULATORS OF CD8+T CELL DIFFERENTIATION.
(16) NEW YORK UNIVERSITY MEDICAL CENTER550 FIRST AVENUE NEW YORK,NY10016	11-3556230	501(C)(3)	145,500	CHARACTERIZATION OF A NOVEL MOLECULAR COMPARTMENT NOVEL EPIGENETIC AND TRANSCRIPTIONAL REGULATORS OF CD8+T CELL DIFFERENTIATION.
(17) NEW YORK UNIVERSITY MEDICAL CENTER550 FIRST AVENUE NEW YORK,NY10016	11-3556230	501(C)(3)	145,500	MOLECULAR MECHANISMS OF DENDRITIC CELL MEDIATED TR IMMUNOLOGY ONLINE JOURNAL CANCER IMMUNITY
(18) NORTHWESTERN UNIVERSITY633 CLARK STREET EVANSTON,IL60208	11-3556230	501(C)(3)	200,000	MOLECULAR MECHANISMS OF ACTION OF AHR IN T CELL DI REMODELING AND LYTIC GRANULE RECYCLING IN HUMAN NATURAL KILLER CELLS.
(19) ROSWELL PARK CANCER INSTITUTEELM CARLTON STREETS BUFFALO,NY14203	36-2167817	501(C)(3)	225,000	CANCER RESEARCH INSTITUTE ANNA-MARIA KELLEN CLINIC MELANOMA NATURAL KILLER CELLS.
(20) ROSWELL PARK CANCER INSTITUTEELM CARLTON STREETS BUFFALO,NY14203	14-1402155	501(C)(3)	300,000	CORE CVC FUNDING PROGENITOR POPULATIONS IN NORMAL AND CANCER CELLS.
(21) ROSWELL PARK CANCER INSTITUTEELM CARLTON STREETS BUFFALO,NY14203	14-1402155	501(C)(3)	2,500,000	CVAF: TREMI ESO VACCINE IN OVARIAN CANCER TRIAL TO ASSESS THE FEASIBILITY AND SAFETY OF ADOPTIVELY TRANSFERRING AUTOLOGOUS CD4 AND CD8 NY-ESO-1 SPECIFIC T CELLS IN PATIENTS WITH UNRESECTABLE MELANOMA.
(22) THE ROCKEFELLER UNIVERSITY1230 YORK AVENUE NEW YORK,NY10065	14-1402155	501(C)(3)	145,500	ENHANCED ANTI-TUMOR IMMUNITY BY REGULATION OF IGG EFFORTS AND SEROMICS ON BEHALF OF THE OCWG ADOPTIVELY TRANSFERRING AUTOLOGOUS CD4 AND CD8 NY-ESO-1 SPECIFIC T CELLS IN PATIENTS WITH UNRESECTABLE MELANOMA.
(23) UNIVERSITY OF CALIFORNIA BERKELEY200 CALIFORNIA HALL BERKELEY,CA94720	13-1624158	501(C)(3)	145,500	MOLECULAR MECHANISMS OF T CELL ACTIVATION BY THE T EFFORTS AND SEROMICS ON BEHALF OF THE OCWG
(24) UNIVERSITY OF CALIFORNIA SAN FRANCISCO513 PARNASSUS AVENUE SAN FRANCISCO,CA941430410	94-6002123	501(C)(3)	145,500	ROLE OF EBI2 AND ITS OXYSTEROL LIGANDS IN ADAPTIVE DIFFERENTATION BY NONCODING RNA
(25) UNIVERSITY OF COLORADO4200 EAST 9TH AVENUE DENVER,CO80262	94-6036493	501(C)(3)	225,000	PREDOC PROGRAM AGONIST POLY-ICLC AS AN ADJUVANT FOR NY-ESO-1 PROTEIN VACCINATION WITH OR WITHOUT MONTANIDE R ISA-51 VG IN PATIENTS WITH HIGH RISK MELANOMA IN COMPLETE CLINICAL REMISSION.
(26) UNIVERSITY OF MARYLAND4101 CHESAPEAKE BUILDING COLLEGE PARK,MD20742	84-6000555	501(C)(3)	145,500	USE OF DIRECTED EVOLUTION OT ASSEMBLE TCR-MHC-CD4 IMMUNOLOGICAL SYNAPSE-KINAPSE BALANCE. PROTEIN VACCINATION WITH OR WITHOUT MONTANIDE R ISA-51 VG IN PATIENTS WITH HIGH RISK MELANOMA IN COMPLETE CLINICAL REMISSION.
(27) UNIVERSITY OF MICHIGAN MEDICAL SCHOOL1301 CATHERINE ROAD ANN ARBOR,MI48109	52-2197313	501(C)(3)	95,000	INTEGRATION OF THE TRANSCRIPTIONAL NETWORK THAT RE IMMUNOLOGICAL SYNAPSE-KINAPSE BALANCE.
(28) UNIVERSITY OF MINNESOTA MINNEAPOLIS100 CHURCH STREE SE MINNEAPOLIS,MN55455	38-6006309	501(C)(3)	145,500	IL-4 PRODUCED BY INKT CELLS DIRECTS THE DEVELOPMEN SPHEROID OVARIAN CANCER CELL AND NONSPHEROID CANCER CELL BY SEREX
(29) UNIVERSITY OF MINNESOTA MINNEAPOLIS100 CHURCH STREE SE MINNEAPOLIS,MN55455	41-6007513	501(C)(3)	145,500	DIRECT TRACKING OF VACCINE SPECIFIC B CELLS FROM N OCWG MEMBERS TESTING FOR CT ANTIGENS GENERAITON OF TUMOR LINES AND AUTOLOGOUS PBMCS. TESTING AND CHARACTERIZATION OF NOVEL TARGETS IDENTIFIED BY SEREX AND TCELL CLONING
(30) UNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE3600 MARKET STREET PHILADELPHIA,PA191042646	41-6007513	501(C)(3)	145,500	REGULATION OF PROTECTIVE IMMUNITY FOLLOWING ENTERI IMMUNOTHERAPY OF TUMOR LINES AND AUTOLOGOUS PBMCS. TESTING AND CHARACTERIZATION OF NOVEL TARGETS IDENTIFIED BY SEREX AND TCELL CLONING
(31) UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE1959 NE PACIFIC STREET SEATTLE,WA98195	23-1352685	501(C)(3)	145,500	A TCELL INTRINSIC ROLE FOR CASPASE-1 IN THE IMMUNE DISEASE IN CHILDHOOD.
(32) UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE1959 NE PACIFIC STREET SEATTLE,WA98195	94-3079432	501(C)(3)	145,500	REPROGRAMMING TOLERANT CD8 T CELLS SPECIFIC FOR SE REGULATING B CELL IMMUNE TOLERANCE.
(33) UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE1959 NE PACIFIC STREET SEATTLE,WA98195	94-3079432	501(C)(3)	95,000	T CELL THERAPY OF PANCREATIC CANCER TARGETING NORM REGULATES PHAGOCYTOSIS OF APOPTOTIC CELLS IN DROSOPHILA
(34) UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE1959 NE PACIFIC STREET SEATTLE,WA98195	94-3079432	501(C)(3)	145,500	A NEW CLASS OF MULTIFUNCTIONAL SMART POLYMERS FOR II EXPRESSION IN INFILTRATING MACROPHAGES AND DENDRITIC CELLS IN OVARIAN CANCER.
(35) WASHINGTON UNIVERSITY SCHOOL OF MEDICINE660 S EUCLID AVENUE ST LOUIS,MO63110	94-3079432	501(C)(3)	145,500	ROLE OF TYPE I INTERFERONS IN ANTI-TUMOR IMMUNITY STUDY. DENDRITIC CELLS IN OVARIAN CANCER.
(36) WASHINGTON UNIVERSITY SCHOOL OF MEDICINE660 S EUCLID AVENUE ST LOUIS,MO63110	43-0653611	501(C)(3)	145,500	NOROVIRUS PERSISTENCE AND ITS CONTRIBUTION TO TUMO STUDY.
(37) WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY1300 YORK AVENUE NEW YORK,NY10065	43-0653611	501(C)(3)	145,500	STRUCTUAL AND BIOCHEMICAL ELUCIDATION OF THE MEMBR SPONTANEIOUS IMMUNE RESPONSES AGAINS MAGE-C2/CT 10 IN PROSTATE CANCER PATIENTS.
(38) YALE UNIVERSITY SCHOOL OF MEDICINE333 Cedar Street New Haven,CT06520	11-3162397	501(C)(3)	145,500	SENSING GUT MICROBIOTA THROUGH G PROTEIN COUPLED R 157-165 HLA-A2 SPECIFIC REDIRECTED T CELLS. 10 IN PROSTATE CANCER PATIENTS.
(39) ZERO The Project to End Prostate Cancer515 King Street Suite 420 Alexandria,VA22314	59-3400922	501(c)(3)	50,000	Prostate Screening 157-165 HLA-A2 SPECIFIC REDIRECTED T CELLS.

Enter total number of section 501(c)(3) and government organizations ......................... Bullet Image

Enter total number of other organizations ................................ . Bullet Image

For Privacy Act and Paperwork Reduction Act Notice, see the Instructions for Form 990.

Cat. No. 50055P

Schedule I (Form 990) 2010

Page 2

Part III

Grants and Other Assistance to Individuals in the United States. Complete if the organization answered "Yes" to Form 990, Part IV, line 22.
Use Schedule I-1 (Form 990) if additional space is needed.

(a)Type of grant or assistance	(b)Number of recipients	(c)Amount of cash grant	(d)Amount of non-cash assistance	(e)Method of valuation (book, FMV, appraisal, other)	(f)Description of non-cash assistance

Part IV

Supplemental Information. Complete this part to provide the information required in Part I, line 2, and any other additional information.

Identifier	Return Reference	Explanation
GRANT MONITORING	SCHEDULE I PART I	CANCER RESEARCH INSTITUTE INC REQUIRES EACH GRANT RECIPIENT TO FILE A PERIODIC STATUS REPORT PRIOR TO GRANT DISBURSEMENT.

Schedule I (Form 990) 2010

Additional Data

Software ID:
Software Version:

- TIN:

Schedule J
(Form 990)

Department of the Treasury
Internal Revenue Service

Compensation Information

For certain Officers, Directors, Trustees, Key Employees, and Highest
Compensated Employees
SchJMediumBullet

Complete if the organization answered "Yes" to Form 990,
Part IV, question 23.
SchJMediumBullet

Attach to Form 990. SchJMediumBullet

See separate instructions.

OMB No. 1545-0047

2010

Open to Public Inspection

Name of the organization

CANCER RESEARCH INSTITUTE

Employer identification number

13-1837442

Part I

Questions Regarding Compensation

Yes

Check the appropiate box(es) if the organization provided any of the following to or for a person listed in Form
990, Part VII, Section A, line 1a. Complete Part III to provide any relevant information regarding these items.

First-class or charter travel Housing allowance or residence for personal use

Travel for companions Payments for business use of personal residence

Tax idemnification and gross-up payments Health or social club dues or initiation fees

Discretionary spending account Personal services (e.g., maid, chauffeur, chef)

If any of the boxes in line 1a are checked, did the organization follow a written policy regarding payment or reimbursement orprovision of all the expenses described above? If "No," complete Part III to explain....

Did the organization require substantiation prior to reimbursing or allowing expenses incurred by all
officers, directors, trustees, and the CEO/Executive Director, regarding the items checked in line 1a? ....

Indicate which, if any, of the following the organization uses to establish the compensation of the
organization's CEO/Executive Director. Check all that apply.

Compensation committee Written employment contract

Independent compensation consultant Compensation survey or study

Form 990 of other organizations Approval by the board or compensation committee

During the year, did any person listed in Form 990, Part VII, Section A, line 1a with respect to the filing organization or a related organization:

Receive a severance payment or change-of-control payment? ...............

Participate in, or receive payment from, a supplemental nonqualified retirement plan? ........

Participate in, or receive payment from, an equity-based compensation arrangement? ........

If "Yes" to any of lines 4a-c, list the persons and provide the applicable amounts for each item in Part III.

Only 501(c)(3) and 501(c)(4) organizations only must complete lines 5-9.

For persons listed in form 990, Part VII, Section A, line 1a, did the organization pay or accrue any
compensation contingent on the revenues of:

The organization? ...........................

Any related organization? .........................

If "Yes," to line 5a or 5b, describe in Part III.

For persons listed in form 990, Part VII, Section A, line 1a, did the organization pay or accrue any
compensation contingent on the net earnings of:

The organization? ...........................

Any related organization? .........................

If "Yes," to line 6a or 6b, describe in Part III.

For persons listed in Form 990, Part VII, Section A, line 1a, did the organization provide any non-fixed
payments not described in lines 5 and 6? If "Yes," describe in Part III ............

Were any amounts reported in Form 990, Part VII, paid or accured pursuant to a contract that was
subject to the initial contract exception described in Regs. section 53.4958-4(a)(3)? If "Yes," describe
in Part III .............................

If "Yes" to line 8, did the organization also follow the rebuttable presumption procedure described in Regulations section 53.4958-6(c)? .........................

For Privacy Act and Paperwork Reduction Act Notice, see the Intructions for Form 990

Cat. No. 50053T

Schedule J (Form 990) 2010

Page 2

Part II

Officers, Directors, Trustees, Key Employees, and Highest Compensated Employees. Use Schedule J-1 if additional space needed.

For each individual whose compensation must be reported in Schedule J, report compensation from the organization on row (i) and from related organizations, described in the
instructions on row (ii). Do not list any individuals that are not listed on Form 990, Part VII.

Note. The sum of columns (B)(i)-(iii) must equal the applicable column (D) or column (E) amounts on Form 990, Part VII, line 1a.

(A) Name		(B) Breakdown of W-2 and/or 1099-MISC compensation			(C) Retirement and other deferred compensation	(D) Nontaxable benefits	(E) Total of columns (B)(i)-(D)	(F) Compensation reported in prior Form 990 or Form 990-EZ
(A) Name		(i) Base compensation	(ii) Bonus & incentive compensation	(iii) Other reportable compensation	(C) Retirement and other deferred compensation	(D) Nontaxable benefits	(E) Total of columns (B)(i)-(D)
(1) Jill O'Donnell Tormey	(i) (ii)	351,074 0	0 0	0 0	34,500 0	23,289 0	408,863 0	0 0
(2) Alfred R Massidas	(i) (ii)	238,276 0	0 0	0 0	23,800 0	23,289 0	285,365 0	0 0
(3) LYNNE A RAPINO	(i) (ii)	189,120 0	0 0	0 0	18,900 0	23,290 0	231,310 0	0 0
(4) ADAM M KOLOM	(i) (ii)	300,000 0	0 0	0 0	27,500 0	9,166 0	336,666 0	0 0

Schedule J (Form 990) 2010

Page 3

Part III

Supplemental Information

Complete this part to provide the information, explanation, or descriptions required for Part I, lines 1a, 1b, 4c, 5a, 5b, 6a, 6b, 7, and 8. Also complete this part for any additional information.

Identifier	Return Reference	Explanation

Schedule J (Form 990) 2010

Additional Data

Software ID:
Software Version:

- TIN:

SCHEDULE M
(Form 990)

Department of the Treasury

Internal Revenue Service

NonCash Contributions

Complete if the organization answered "Yes" on Form 990, Part IV, lines 29 or 30.
Right pointing arrow large image

Attach to Form 990.

OMB No. 1545-0047

2010

Open to Public Inspection

Name of the organization

CANCER RESEARCH INSTITUTE

Employer identification number

13-1837442

Part I

Types of Property

	(a) Check if applicable	(b) Number of Contributions or items contributed	(c) Contribution amounts reported on Form 990, Part VIII, line 1g	(d) Method of determining contribution amounts
1 Art—Works of art ....
2 Art—Historical treasures .
3 Art—Fractional interests ..
4 Books and publications ..
5 Clothing and household goods .......
6 Cars and other vehicles ..	X	12	213,096	APPRAISAL
7 Boats and planes ....
8 Intellectual property ...
9 Securities—Publicly traded .	X	16	266,742	FMV
10 Securities—Closely held stock .
11 Securities—Partnership, LLC, or trust interests ....
12 Securities—Miscellaneous ..
13 Qualified conservation contribution—Historic structures .....
14 Qualified conservation contribution—Other ...
15 Real estate—Residential .
16 Real estate—Commercial ..
17 Real estate—Other ...
18 Collectibles .....
19 Food inventory ...
20 Drugs and medical supplies .
21 Taxidermy ......
22 Historical artifacts ....
23 Scientific specimens ..
24 Archeological artifacts ...
25 Other ( )
26 Other ( )
27 Other ( )
28 Other ( )

Number of Forms 8283 received by the organization during the tax year for contributions
for which the organization completed Form 8283, Part IV, Donee Acknowledgement ...

Yes

30a

During the year, did the organization receive by contribution any property reported in Part I, lines 1-28 that it

must hold for at least three years from the date of the initial contribution, and which is not required to be used

for exempt purposes for the entire holding period? ..................

30a

If "Yes," describe the arrangement in Part II.

Does the organization have a gift acceptance policy that requires the review of any non-standard contributions?

Yes

32a

Does the organization hire or use third parties or related organizations to solicit, process, or sell non-cash

contributions? ............................

32a

Yes

If "Yes," describe in Part II.

If the organization did not report revenues in column (c) for a type of property for which column (a) is checked,

describe in Part II.

For Privacy Act and Paperwork Reduction Act Notice, see the Instructions for Form 990.

Cat. No. 51227J

Schedule M (Form 990) 2010

Page 2

Part II

Supplemental Information. Complete this part to provide the information required by Part I, lines 30b,
32b, and 33. Also complete this part for any additional information.

Identifier	Return Reference	Explanation
SCHEDULE M - NON-CASH CONTRIBUTIONS	THIRD PARTY ADMINISTRATOR	CRI USES A THIRD PARTY SERVICE ORGANIZATION TO RECEIVE THE DONATED VEHICLES, APPRAISE THE ITEMS AND PROMPTLY SELL THEM. FOR SERVICES RENDERED THE SERVICE ORGANIZATION RETAINS 30% OF THE GROSS PROCEEDS.

Schedule M (Form 990) 2010

Additional Data

Software ID:
Software Version:

- TIN:

SCHEDULE O
(Form 990 or 990-EZ)

Department of the Treasury
Internal Revenue Service

Supplemental Information to Form 990 or 990-EZ

Complete to provide information for responses to specific questions on
Form 990 or to provide any additional information.
MediumBullet

Attach to Form 990 or 990-EZ.

OMB No. 1545-0047

2010

Open to Public
Inspection

Name of the organization

CANCER RESEARCH INSTITUTE

Employer identification number

13-1837442

Identifier	Return Reference	Explanation
PART VI - GOVERNANCE, MANAGEMENT AND DISCLOSURE, LINE 10	PROCESS FOR REVIEW OF FORM 990	The controller works with the Auditing Firm to complete the Form 990. Draft copy is shared with the CEO for review and edits. Final draft is sent to the Budget and Finance Committee for their review and comment. Final copy is then filed electronically and a copy is posted on CRI"s website.
PART VI - GOVERNANCE, MANAGEMENT AND DISCLOSURE, LINE 12C	CONFLICT OF INTEREST POLICY	CRI REGULARLY AND CONSISTENTLY MONITORS AND ENFORCES COMPLIANCE WITH THE CONFLICT OF INTEREST POLICY BY REQUIRING ALL OFFICERS, TRUSTEES AND KEY EMPLOYEES TO RE-AFFIRM THE POLICY ANNUALLY.
PART VI - GOVERNANCE, MANAGEMENT AND DISCLOSURE, LINE 15	EXECUTIVE COMPENSATION POLICY	THE PROCESS FOR DETERMINING COMPENSATION OF THE CEO IS DETERMINED BY USING COMPARABLE DATE AND IS REVIEWED BY THE BOARD OF TRUSTEES' CO-CHAIRMEN.
PART VI - GOVERNANCE, MANAGEMENT AND DISCLOSURE, LINE 19	PUBLIC INSPECTION	1. GOVERNING DOCUMENTS ARE NOT MADE AVAILABLE TO THE PUBLIC; 2. CONFLICT OF INTEREST POLICY IS AVAILABLE UPON REQUEST; AND 3. FINANCIAL STATEMENTS ARE AVAILABLE ON CRI'S WEBSITE AND UPON REQUEST

For Paperwork Reduction Act Notice, see the Instructions for Form 990 or 990-EZ.

Cat. No. 51056K

Schedule O (Form 990 or 990-EZ) 2010

Additional Data

Software ID:
Software Version:

1	Was the organization a U.S. transferor of property to a foreign corporation during the tax year? If "Yes," the organization may be required to file Form 926 (see instructions for Form 926).................	Yes	No
2	Did the organization have an interest in a foreign trust during the tax year? If " Yes," the organization may be required to file Form 3520 and/or Form 3520-A. (see instructions for Forms 3520 and 3520-A)..........	Yes	No
3	Did the organization have an ownership interest in a foreign corporation during the tax year? If "Yes," the organization may be required to file Form 5471, Information Return of U.S. Persons with respect to Certain Foreign Corporations. (see instructions for Form 5471)..............................	Yes	No
4	Was the organization a direct or indirect shareholder of a passive foreign investment company or a qualified electing fund during the tax year? If "Yes," the organization may be required to file Form 8621, Return by a Shareholder of a Passive Foreign Investment Company or Qualified Electing Fund. (see instructions for Form 8621)	Yes	No
5	Did the organization have an ownership interest in a foreign partnership during the tax year? If "Yes," the organization may be required to file Form 8865, Return of U.S. Persons with respect to Certain Foreign Partnerships. (see instructions for Form 8865)....................................	Yes	No
6	Did the organization have any operations in or related to any boycotting countries during the tax year? If "Yes," the organization may be required to file Form 5713, International Boycott Report (see instructions for Form 5713)................................................	Yes	No