Form990
Click to see attachment
Department of the Treasury
Internal Revenue Service
Return of Organization Exempt From Income Tax
Under section 501(c), 527, or 4947(a)(1) of the Internal Revenue Code (except black lung benefit trust or private foundation)

MediumBullet The organization may have to use a copy of this return to satisfy state reporting requirements.
OMB No. 1545-0047
2010
Open to Public Inspection
A For the calendar year, or tax year beginning 12-01-2010 and ending 11-30-2011
BCheck if applicable:
CName of organization
VAN ANDEL RESEARCH INSTITUTE
 
Doing Business As
 
 
Number and street (or P.O. box if mail is not delivered to street address)
333 BOSTWICK AVENUE NE
 
Room/suite
City or town, state or country, and ZIP + 4
GRAND RAPIDS, MI49503
D Employer identification number

52-2000823
E Telephone number

G Gross receipts $ 64,949,975
F Name and address of principal officer:
TIMOTHY J MYERS
333 BOSTWICK AVENUE NE
GRAND RAPIDS,MI49503
I
Tax-exempt status: (   ) LeftBullet (insert no.) or
J
Website:MediumBullet
WWW.VAI.ORG
H(a)
Is this a group return for
affiliates?
H(b)
Are all affiliates included?
If "No," attach a list. (see instructions)
H(c)
Group exemption number MediumBullet  
K Form of organization:
 
L Year of formation: 1996
M State of legal domicile: MI
Part I
Summary
Activities & Governance 1 Briefly describe the organization’s mission or most significant activities: MEDICAL RESEARCH ORGANIZATION
2 Check this box MediumBullet
3 Number of voting members of the governing body (Part VI, line 1a) .... 3 7
4 Number of independent voting members of the governing body (Part VI, line 1b) .... 4 4
5 Total number of individuals employed in calendar year 2010 (Part V, line 2a) ... 5 345
6 Total number of volunteers (estimate if necessary) .... 6 0
7a Total unrelated business revenue from Part VIII, column (C), line 12 .. 7a 1,293,324
b Net unrelated business taxable income from Form 990-T, line 34 .. 7b 319,272
Revenues; Prior Year Current Year
8 Contributions and grants (Part VIII, line 1h) ......... 69,868,505 57,012,820
9 Program service revenue (Part VIII, line 2g) ......... 1,332,729 1,522,584
10 Investment income (Part VIII, column (A), lines 3, 4, and 7d ) .... -272,304 819,423
11 Other revenue (Part VIII, column (A), lines 5, 6d, 8c, 9c, 10c, and 11e) 5,766,282 4,334,013
12 Total revenue—add lines 8 through 11 (must equal Part VIII, column (A), line 12)................... 76,695,212 63,688,840
Expenses; 13 Grants and similar amounts paid (Part IX, column (A), lines 1–3 )... 221,029 340,825
14 Benefits paid to or for members (Part IX, column (A), line 4) .... 0 0
15 Salaries, other compensation, employee benefits (Part IX, column (A), lines 5–10) 22,508,665 26,065,382
16a Professional fundraising fees (Part IX, column (A), line 11e).... 0 0
b Total fundraising expenses (Part IX, column (D), line 25) MediumBullet465,513    
17 Other expenses (Part IX, column (A), lines 11a–11d, 11f–24f).... 69,776,826 39,147,197
18 Total expenses. Add lines 13–17 (must equal Part IX, column (A), line 25) 92,506,520 65,553,404
19 Revenue less expenses. Subtract line 18 from line 12...... -15,811,308 -1,864,564
Net Assets or Fund Balances; Beginning of Current Year End of Year
20 Total assets (Part X, line 16)............ 253,776,425 270,167,888
21 Total liabilities (Part X, line 26)............ 312,690,617 358,085,475
22 Net assets or fund balances. Subtract line 21 from line 20 ..... -58,914,192 -87,917,587
Part II
Signature Block
Under penalties of perjury, I declare that I have examined this return, including accompanying schedules and statements, and to the best of my knowledge and belief, it is true, correct, and complete. Declaration of preparer (other than officer) is based on all information of which preparer has any knowledge.
Sign Here
JumboBullet
Signature of officer Date
JumboBullet
Type or print name and title.
Paid Preparer's Use Only Preparer's
signatureBig Right Arrow 		Date
right pointing bullet image Preparer’s taxpayer identification number
(see instructions)
Firm’s name (or yours
if self-employed),
address, and ZIP + 4Big Right Arrow




 		EIN right pointing bullet image
Phone no. right pointing bullet image
May the IRS discuss this return with the preparer shown above? (see instructions) .........
For Privacy Act and Paperwork Reduction Act Notice, see the separate instructions.
Cat. No. 11282Y
Form 990 (2010)
Form 990 (2010)
Page 2
Part III
Statement of Program Service Accomplishments
Check if Schedule O contains a response to any question in this Part III . . . . . . . . . .
1
Briefly describe the organization’s mission: MEDICAL RESEARCH ORGANIZATION
2
Did the organization undertake any significant program services during the year which were not listed on
the prior Form 990 or 990-EZ? ....................
If “Yes,” describe these new services on Schedule O.
3
Did the organization cease conducting, or make significant changes in how it conducts, any program services? ..........................
If “Yes,” describe these changes on Schedule O.
4
Describe the exempt purpose achievements for each of the organization’s three largest program services by expenses.
Section 501(c)(3) and 501(c)(4) organizations and section 4947(a)(1) trusts are required to report the amount of grants and allocations to others, the total expenses, and revenue, if any, for each program service reported.
4a (Code:   ) (Expenses $ 2,294,558 including grants of $   ) (Revenue $   )
THE LABORATORY OF STRUCTURAL SCIENCES IS FOCUSED ON STUDYING THE STRUCTURES AND FUNCTIONS OF PROTEIN/ LIGAND COMPLEXES THAT PLAY KEY ROLES IN MAJOR HORMONE SIGNALING PATHWAYS. SEE SCHEDULE O FOR FURTHER INFORMATION ABOUT THIS PROGRAM.
4b (Code:   ) (Expenses $ 1,913,728 including grants of $   ) (Revenue $   )
THE LABORATORY OF MOLECULAR ONCOLOGY HAS FOCUSED ON UNDERSTANDING THE NUMEROUS AND DIVERSE ROLES THAT MET PLAYS IN MALIGNANT PROGRESSION AND METASTASIS. SCHEDULE O PROVIDES FURTHER INFORMATION REGARDING THIS PROGRAM'S ACCOMPLISHMENTS.
4c (Code:   ) (Expenses $ 1,374,533 including grants of $   ) (Revenue $ 1,137,649 )
THE LABORATORY FOR TRANSLATIONAL MEDICINE IS FOCUSED ON THE DEVELOPMENT AND UTILIZATION OF MOLECULAR AND COMPUTATIONAL TECHNOLOGIES TO STUDY HOW A TUMOR SPREADS TO DISTANT PARTS OF THE BODY FROM ITS ORIGINAL LOCATION (METASTASIS), AND IDENTIFYING APPROACHES TO TREAT SUCH AGGRESSIVE CANCERS USING A "PERSONALIZED MEDICINE" APPROACH. SEE SCHEDULE O FOR FURTHER INFORMATION ABOUT THIS PROGRAM.
(Code:   ) (Expenses $ 38,027,999 including grants of $ 490,825 ) (Revenue $ 2,080,528 )
4d Other program services. (Describe in Schedule O.)
(Expenses $ 38,027,999 including grants of $ 490,825 ) (Revenue $ 2,080,528 )
4e Total program service expensesMediumBullet$ 43,610,818
Form 990 (2010)
Form 990 (2010)
Page 3
Part IV
Checklist of Required Schedules
Yes
No
1
Is the organization described in section 501(c)(3) or 4947(a)(1) (other than a private foundation)? If “Yes,” complete Schedule AClick to see attachment.....................
1
Yes
 
2
Is the organization required to complete Schedule B, Schedule of Contributors? Click to see attachment........
2
Yes
 
3
Did the organization engage in direct or indirect political campaign activities on behalf of or in opposition to candidates for public office? If “Yes,” complete Schedule C, Part IClick to see attachment..........
3
 
No
4
Section 501(c)(3) organizations. Did the organization engage in lobbying activities? If “Yes,” complete Schedule C,
Part IIClick to see attachment.........................
4
Yes
 
5
Is the organization a section 501(c)(4), 501(c)(5), or 501(c)(6) organization that receives membership dues, assessments, or similar amounts as defined in Revenue Procedure 98-19? If “Yes,” complete Schedule C, Part III........................
5
 
 
6
Did the organization maintain any donor advised funds or any similar funds or accounts where donors have the right to provide advice on the distribution or investment of amounts in such funds or accounts? If “Yes,” complete
Schedule D, Part IClick to see attachment.......................
6
 
No
7
Did the organization receive or hold a conservation easement, including easements to preserve open space,
the environment, historic land areas or historic structures? If “Yes,” complete Schedule D, Part IIClick to see attachment...
7
 
No
8
Did the organization maintain collections of works of art, historical treasures, or other similar assets? If “Yes,” complete Schedule D, Part III Click to see attachment....................
8
Yes
 
9
Did the organization report an amount in Part X, line 21; serve as a custodian for amounts not listed in Part X; or provide credit counseling, debt management, credit repair, or debt negotiation services? If “Yes,”
complete Schedule D, Part IVClick to see attachment...................
9
 
No
10
Did the organization, directly or through a related organization, hold assets in term, permanent,or quasi-endowments? If “Yes,” complete Schedule D, Part VClick to see attachment
10
 
No
11
If the organization’s answer to any of the following questions is ‘Yes,’ then complete Schedule D, Parts VI, VII, VIII, IX, or X as applicable:
a
Did the organization report an amount for land, buildings, and equipment in Part X, line10? If “Yes,” complete Schedule D, Part VI.Click to see attachment
11a
Yes
 
b
Did the organization report an amount for investments—other securities in Part X, line 12 that is 5% or more of its total assets reported in Part X, line 16? If “Yes,” complete Schedule D, Part VII.Click to see attachment
11b
 
No
c
Did the organization report an amount for investments—program related in Part X, line 13 that is 5% or more of its total assets reported in Part X, line 16? If “Yes,” complete Schedule D, Part VIII.Click to see attachment
11c
 
No
d
Did the organization report an amount for other assets in Part X, line 15 that is 5% or more of its total assets reported in Part X, line 16? If “Yes,” complete Schedule D, Part IX.Click to see attachment
11d
Yes
 
e
Did the organization report an amount for other liabilities in Part X, line 25? If “Yes,” complete Schedule D, Part X.Click to see attachment
11e
Yes
 
f
Did the organization’s separate or consolidated financial statements for the tax year include a footnote that addresses the organization’s liability for uncertain tax positions under FIN 48 (ASC 740)? If “Yes,” complete Schedule D, Part X.Click to see attachment
11f
 
No
12a
Did the organization obtain separate, independent audited financial statements for the tax year? If “Yes,” complete Schedule D, Parts XI, XII, and XIII Click to see attachment
12a
 
No
b
Was the organization included in consolidated, independent audited financial statements for the tax year? If “Yes,” and if the organization answered ‘No’ to line 12a, then completing Schedule D, Parts XI, XII, and XIII is optional Click to see attachment
12b
Yes
 
13
Is the organization a school described in section 170(b)(1)(A)(ii)? If “Yes,” complete Schedule E
13
 
No
14a
Did the organization maintain an office, employees, or agents outside of the United States?....
14a
Yes
 
b
Did the organization have aggregate revenues or expenses of more than $10,000 from grantmaking, fundraising, business, and program service activities outside the United States? If “Yes,” complete Schedule F, Part I......... Click to see attachment
14b
Yes
 
15
Did the organization report on Part IX, column (A), line 3, more than $5,000 of grants or assistance to any organization or entity located outside the U.S.? If “Yes,” complete Schedule F, Part II.. Click to see attachment
15
 
No
16
Did the organization report on Part IX, column (A), line 3, more than $5,000 of aggregate grants or assistance to individuals located outside the U.S.? If “Yes,” complete Schedule F, Part III.. Click to see attachment
16
 
No
17
Did the organization report a total of more than $15,000, of expenses for professional fundraising services on Part IX, column (A), lines 6 and 11e? If “Yes,” complete Schedule G, Part I
17
 
No
18
Did the organization report more than $15,000 total of fundraising event gross income and contributions on Part VIII, lines 1c and 8a? If “Yes,” complete Schedule G, Part II..........
18
 
No
19
Did the organization report more than $15,000 of gross income from gaming activities on Part VIII, line 9a? If “Yes,” complete Schedule G, Part III...................
19
 
No
Form 990 (2010)
Form 990 (2010)
Page 4
Part IV
Checklist of Required Schedules (continued)
20a
Did the organization operate one or more hospitals? If “Yes,” complete Schedule H.....
20a
 
No
b
Did the organization attach its audited financial statement to this return? Note: All Form 990 filers that operate one or more hospitals must attach audited financial statements. .....
20b
 
 
21
Did the organization report more than $5,000 of grants and other assistance to governments and organizations in the United States on Part IX, column (A), line 1? If “Yes,” complete Schedule I, Parts I and II.. Click to see attachment
21
 
No
22
Did the organization report more than $5,000 of grants and other assistance to individuals in the United States on Part IX, column (A), line 2? If “Yes,” complete Schedule I, Parts I and III..... Click to see attachment
22
Yes
 
23
Did the organization answer “Yes” to Part VII, Section A, questions 3, 4, or 5, about compensation of the organization’s current and former officers, directors, trustees, key employees, and highest compensated employees? If “Yes,” complete Schedule J................ Click to see attachment
23
Yes
 
24a
Did the organization have a tax-exempt bond issue with an outstanding principal amount of more than $100,000 as of the last day of the year, that was issued after December 31, 2002? If “Yes,” answer questions 24b–24d and complete Schedule K. If “No,” go to line 25................ Click to see attachment
24a
Yes
 
b
Did the organization invest any proceeds of tax-exempt bonds beyond a temporary period exception?...
24b
 
No
c
Did the organization maintain an escrow account other than a refunding escrow at any time during the year
to defease any tax-exempt bonds?......................
24c
 
No
d
Did the organization act as an “on behalf of” issuer for bonds outstanding at any time during the year?...
24d
 
No
25a
Section 501(c)(3) and 501(c)(4) organizations. Did the organization engage in an excess benefit transaction with a disqualified person during the year? If “Yes,” complete Schedule L, Part I......
25a
 
No
b
Is the organization aware that it engaged in an excess benefit transaction with a disqualified person in a prior year, and that the transaction has not been reported on any of the organization’s prior Forms 990 or 990-EZ? If “Yes,” complete Schedule L, Part I................
25b
 
No
26
Was a loan to or by a current or former officer, director, trustee, key employee, highly compensated employee, or disqualified person outstanding as of the end of the organization’s tax year? If “Yes,” complete Schedule L,
Part II...........................
26
 
No
27
Did the organization provide a grant or other assistance to an officer, director, trustee, key employee, substantial contributor, or a grant selection committee member, or to a person related to such an individual? If “Yes,” complete Schedule L, Part III...............
27
 
No
28
Was the organization a party to a business transaction with one of the following parties? (see Schedule L, Part IV instructions for applicable filing thresholds, conditions, and exceptions):
a
A current or former officer, director, trustee, or key employee? If “Yes,” complete Schedule L, Part IV .........................
28a
 
No
b
A family member of a current or former officer, director, trustee, or key employee? If “Yes,”
complete Schedule L, Part IV...................
28b
 
No
c
An entity of which a current or former officer, director, trustee, or key employee (or a family member thereof) was an officer, director, trustee, or owner? If “Yes,” complete Schedule L, Part IV..
28c
 
No
29
Did the organization receive more than $25,000 in non-cash contributions? If “Yes,” complete Schedule M
29
 
No
30
Did the organization receive contributions of art, historical treasures, or other similar assets, or qualified conservation contributions? If “Yes,” complete Schedule M............
30
 
No
31
Did the organization liquidate, terminate, or dissolve and cease operations? If “Yes,” complete Schedule N,
Part I...........................
31
 
No
32
Did the organization sell, exchange, dispose of, or transfer more than 25% of its net assets? If “Yes,” complete Schedule N, Part II.......................
32
 
No
33
Did the organization own 100% of an entity disregarded as separate from the organization under Regulations sections 301.7701-2 and 301.7701-3? If “Yes,” complete Schedule R, Part I........ Click to see attachment
33
Yes
 
34
Was the organization related to any tax-exempt or taxable entity? If “Yes,” complete Schedule R, Parts II, III, IV, and V, line 1..................... Click to see attachment
34
Yes
 
35
Is any related organization a controlled entity within the meaning of section 512(b)(13)? .....
35
Yes
 
a
Did the organization receive any payment from or engage in any transaction with a controlled entity within the meaning of section 512(b)(13)? If “Yes,” complete Schedule R, Part V, line 2... Click to see attachment
36
Section 501(c)(3) organizations. Did the organization make any transfers to an exempt non-charitable related organization? If “Yes,” complete Schedule R, Part V, line 2........... Click to see attachment
36
 
No
37
Did the organization conduct more than 5% of its activities through an entity that is not a related organization and that is treated as a partnership for federal income tax purposes? If “Yes,” complete Schedule R, Part VIClick to see attachment
37
 
No
38
Did the organization complete Schedule O and provide explanations in Schedule O for Part VI, lines 11 and 19? Note. All Form 990 filers are required to complete Schedule O. ............
38
Yes
 
Form 990 (2010)
Form 990 (2010)
Page 5
Part V
Statements Regarding Other IRS Filings and Tax Compliance
Check if Schedule O contains a response to any question in this Part V . . . . . . . . . .
Yes
No
1a
Enter the number reported in Box 3 of Form 1096. Enter -0- if not applicable. .......
1a
91
b
Enter the number of Forms W-2G included in line 1a. Enter -0- if not applicable.
1b
0
c
Did the organization comply with backup withholding rules for reportable payments to vendors and reportable gaming (gambling) winnings to prize winners? ..................
1c
 
 
2a
Enter the number of employees reported on Form W-3, Transmittal of Wage and Tax Statements filed for the calendar year ending with or within the year covered by this return .....................
2a
345
b
If at least one is reported on line 2a, did the organization file all required federal employment tax returns?

Note. If the sum of lines 1a and 2a is greater than 250, you may be required to e-file. (see instructions)
2b
Yes
 
3a
Did the organization have unrelated business gross income of $1,000 or more during the year?.............................
3a
Yes
 
b
If “Yes,” has it filed a Form 990-T for this year? If “No,” provide an explanation in Schedule O.....
3b
Yes
 
4a
At any time during the calendar year, did the organization have an interest in, or a signature or other authority over, a financial account in a foreign country (such as a bank account or securities account)?.......................
4a
 
No
b
If "Yes," enter the name of the foreign country: MediumBullet
See instructions for filing requirements for Form TD F 90-22.1, Report of Foreign Bank and Financial Accounts.
5a
Was the organization a party to a prohibited tax shelter transaction at any time during the tax year?..
5a
 
No
b
Did any taxable party notify the organization that it was or is a party to a prohibited tax shelter transaction?
5b
 
No
c
If “Yes” to line 5a or 5b, did the organization file Form 8886-T? ........
5c
 
 
6a
Does the organization have annual gross receipts that are normally greater than $100,000, and did the organization solicit any contributions that were not tax deductible?..........
6a
 
No
b
If “Yes,” did the organization include with every solicitation an express statement that such contributions or gifts were not tax deductible?........................
6b
 
 
7
Organizations that may receive deductible contributions under section 170(c).
a
Did the organization receive a payment in excess of $75 made partly as a contribution and partly for goods and services provided to the payor?....................
7a
 
No
b
If “Yes,” did the organization notify the donor of the value of the goods or services provided?.....
7b
 
 
c
Did the organization sell, exchange, or otherwise dispose of tangible personal property for which it was required to file Form 8282?...........................
7c
 
No
d
If “Yes,” indicate the number of Forms 8282 filed during the year ....
7d
 
e
Did the organization receive any funds, directly or indirectly, to pay premiums on a personal benefit contract?..........................
7e
 
No
f
Did the organization, during the year, pay premiums, directly or indirectly, on a personal benefit contract?..
7f
 
No
g
If the organization received a contribution of qualified intellectual property, did the organization file Form 8899 as required?...................
7g
 
 
h
If the organization received a contribution of cars, boats, airplanes, or other vehicles, did the organization file a Form 1098-C?...............
7h
 
 
8
Sponsoring organizations maintaining donor advised funds and section 509(a)(3) supporting organizations. Did the supporting organization, or a donor advised fund maintained by a sponsoring organization, have excess business holdings at any time during the year?................
8
 
 
9
Sponsoring organizations maintaining donor advised funds.
a
Did the organization make any taxable distributions under section 4966?.........
9a
 
 
b
Did the organization make a distribution to a donor, donor advisor, or related person?......
9b
 
 
10
Section 501(c)(7) organizations. Enter:
a
Initiation fees and capital contributions included on Part VIII, line 12 ...
10a
 
b
Gross receipts, included on Form 990, Part VIII, line 12, for public use of club facilities
10b
 
11
Section 501(c)(12) organizations. Enter:
a
Gross income from members or shareholders .........
11a
 
b
Gross income from other sources (Do not net amounts due or paid to other sources against amounts due or received from them.) ........
11b
 
12a
Section 4947(a)(1) non-exempt charitable trusts. Is the organization filing Form 990 in lieu of Form 1041?
12a
 
 
b
If “Yes,” enter the amount of tax-exempt interest received or accrued during the year.
12b
 
13
Section 501(c)(29) qualified nonprofit health insurance issuers.
a
Is the organization licensed to issue qualified health plans in more than one state?
Note. All 501(c)(29) organizations must list in Schedule O each state in which they are licensed to issue qualified health plans, the amount of reserves required by each state, and the amount of reserves the organization allocated to each state.
13a
 
 
b
Enter the aggregate amount of reserves the organization is required to maintain by the states in which the organization is licensed to issue qualified health plans.
13b
 
c
Enter the aggregate amount of reserves on hand.
13c
 
14a
Did the organization receive any payments for indoor tanning services during the tax year?.....
14a
 
 
b
If "Yes," has it filed a Form 720 to report these payments? If “No,” provide an explanation in Schedule O..
14b
 
 
Form 990 (2010)
Form 990 (2010)
Page 6
Part VI
Governance, Management, and Disclosure For each “Yes” response to lines 2 through 7b below, and for a “No” response to lines 8a, 8b, or 10b below, describe the circumstances, processes, or changes in Schedule O. See instructions.
Check if Schedule O contains a response to any question in this Part VI . . . . . . . . . .
Section A. Governing Body and Management
Yes
No
1a
Enter the number of voting members of the governing body at the end of the tax year ..............
1a
7
b
Enter the number of voting members included in line 1a, above, who are independent .................
1b
4
2
Did any officer, director, trustee, or key employee have a family relationship or a business relationship with any other officer, director, trustee, or key employee? .................
2
Yes
 
3
Did the organization delegate control over management duties customarily performed by or under the direct supervision of officers, directors or trustees, or key employees to a management company or other person? ..
3
Yes
 
4
Did the organization make any significant changes to its governing documents since the prior Form 990 was filed?
4
 
No
5
Did the organization become aware during the year of a significant diversion of the organization’s assets? .
5
 
No
6
Does the organization have members or stockholders? ................
6
 
No
7a
Does the organization have members, stockholders, or other persons who may elect one or more members of the governing body? .........................
7a
Yes
 
b
Are any decisions of the governing body subject to approval by members, stockholders, or other persons? ..
7b
 
No
8
Did the organization contemporaneously document the meetings held or written actions undertaken during the year by the following:
a
The governing body? .........................
8a
Yes
 
b
Each committee with authority to act on behalf of the governing body? ............
8b
Yes
 
9
Is there any officer, director, trustee, or key employee listed in Part VII, Section A, who cannot be reached at the organization’s mailing address? If “Yes,” provide the names and addresses in Schedule O .....
9
 
No
Section B. Policies (This Section B requests information about policies not required by the Internal
Revenue Code.)
Yes
No
10a
Does the organization have local chapters, branches, or affiliates? ............
10a
 
No
b
If “Yes,” does the organization have written policies and procedures governing the activities of such chapters, affiliates, and branches to ensure their operations are consistent with those of the organization? ....
10b
 
 
11a
Has the organization provided a copy of this Form 990 to all members of its governing body before filing the form?
11a
Yes
 
b
Describe in Schedule O the process, if any, used by the organization to review the Form 990. .....
12a
Does the organization have a written conflict of interest policy? If “No,” go to line 13.......
12a
 
No
b
Are officers, directors or trustees, and key employees required to disclose annually interests that could give rise to conflicts? ...........................
12b
 
 
c
Does the organization regularly and consistently monitor and enforce compliance with the policy? If “Yes,” describe in Schedule O how this is done ....................
12c
 
 
13
Does the organization have a written whistleblower policy? ...............
13
 
No
14
Does the organization have a written document retention and destruction policy? .........
14
 
No
15
Did the process for determining compensation of the following persons include a review and approval by independent persons, comparability data, and contemporaneous substantiation of the deliberation and decision?
a
The organization’s CEO, Executive Director, or top management official ...........
15a
Yes
 
b
Other officers or key employees of the organization ................
15b
Yes
 
If "Yes" to line a or b, describe the process in Schedule O. (See instructions.)
16a
Did the organization invest in, contribute assets to, or participate in a joint venture or similar arrangement with a taxable entity during the year? ......................
16a
Yes
 
b
If “Yes,” has the organization adopted a written policy or procedure requiring the organization to evaluate its participation in joint venture arrangements under applicable federal tax law, and taken steps to safeguard the organization’s exempt status with respect to such arrangements? ............
16b
 
No
Section C. Disclosure
17
List the States with which a copy of this Form 990 is required to be filedMediumBullet
MI
18
Section 6104 requires an organization to make its Form 1023 (or 1024 if applicable), 990, and 990-T (501(c)(3)s only) available for public inspection. Indicate how you make these available. Check all that apply.
19
Describe in Schedule O whether (and if so, how), the organization makes its governing documents, conflict of interest policy, and financial statements available to the public.
20
State the name, physical address, and telephone number of the person who possesses the books and records of the organization: MediumBullet
TIMOTHY J MYERS CFO
333 BOSTWICK AVENUE NE
GRAND RAPIDS,MI495032518
(616) 234-5368
Form 990 (2010)
Form 990 (2010)
Page 7
Part VII
Compensation of Officers, Directors,Trustees, Key Employees, Highest Compensated Employees, and Independent Contractors
Check if Schedule O contains a response to any question in this Part VII . . . . . . . . . .
Section A. Officers, Directors, Trustees, Key Employees, and Highest Compensated Employees
1a Complete this table for all persons required to be listed. Report compensation for the calendar year ending with or within the organization’s tax year.
RoundBullet List all of the organization’s current officers, directors, trustees (whether individuals or organizations), regardless of amount
of compensation, and current key employees. Enter -0- in columns (D), (E), and (F) if no compensation was paid.

RoundBullet List all of the organization’s current key employees, if any. See instructions for definition of "key employee."
RoundBullet List the organization’s five current highest compensated employees (other than an officer, director, trustee or key employee)
who received reportable compensation (Box 5 of Form W-2 and/or Box 7 of Form 1099-MISC) of more than $100,000 from the
organization and any related organizations.

RoundBullet List all of the organization’s former officers, key employees, or highest compensated employees who received more than $100,000
of reportable compensation from the organization and any related organizations.

RoundBullet List all of the organization’s former directors or trustees that received, in the capacity as a former director or trustee of the
organization, more than $10,000 of reportable compensation from the organization and any related organizations.

List persons in the following order: individual trustees or directors; institutional trustees; officers; key employees; highest
compensated employees; and former such persons.
Check this box if neither the organization nor any related organizations compensated any current or former officer, director, or trustee.
(A)
Name and Title 		(B)
Average hours per week (describe hours for related organizations in Schedule O) 		(C)
Position (check all that apply) 		(D)
Reportable compensation from the organization (W- 2/1099-MISC) 		(E)
Reportable compensation from related organizations (W- 2/1099-MISC) 		(F)
Estimated amount of other compensation from the organization and related organizations
Individual Trustee or Director; Institutional Trustee; Officer; Key Employee; Highest compensated employee; Former;
(1) DAVID VAN ANDEL
CHAIRMAN / CEO
 28.00 X   X       412,250 0 129,965
(2) GEORGE VANDE WOUDE
TRUSTEE/ DIST INVESTIGATOR
 50.00 X           325,763 0 44,345
(3) DR JAMES FAHNER
TRUSTEE
 1.00 X           10,000 0 0
(4) DR FRITZ ROTTMAN PHD
TRUSTEE
 1.00 X           10,000 2,000 0
(5) DR JEFFREY TRENT
PRESIDENT & RESEARCH DIREC
 50.00 X   X       1,043,405 0 303,030
(6) JOSE CARDENAS
TRUSTEE
 1.00 X           10,000 0 0
(7) WILLIAM POST
TRUSTEE
 1.00 X           0 0 0
(8) R JACK FRICK
CHIEF ADMINISTRATIVE OFFICER
 50.00     X       265,597 0 101,087
(9) TIMOTHY MYERS
CHIEF FINANCIAL OFFICER
 50.00     X       156,599 0 90,958
(10) JEFFREY BATTERSHALL
SECRETARY/ INTERIM CHIEF LEGAL
 1.00     X       0 0 0
(11) DAVID WHITESCARVER
SECRETARY/ CHIEF LEGAL OFFICER
 50.00     X       0 0 0
(12) KATHLEEN VOGELSANG
DIR OF INVESTMENTS
 45.00         X   180,737 0 35,576
(13) DR H ERIC XU
DIST INVESTIGATOR
 45.00         X   267,231 0 48,773
(14) DR JAMES RESAU
DIST INVESTIGATOR
 45.00         X   192,433 0 39,977
(15) JOHN BENDER
CLINICAL OPERATIONS DIRECT
 45.00         X   233,240 0 31,603
(16) BRYON CAMPBELL
CHIEF INFORMATION OFFICER
 45.00         X   179,498 0 35,557
(17) STEVE HEACOCK FORMER
CAO / GENERAL COUNSEL
 8.00           X 615,119 0 23,095
Form 990 (2010)
Form 990 (2010)
Page 8
Part VII
Section A. Officers, Directors, Trustees, Key Employees, and Highest Compensated Employees (continued)
(A)
Name and Title 		(B)
Average hours per week (describe hours for related organizations in Schedule O) 		(C)
Position (check all that apply) 		(D)
Reportable compensation from the organization (W- 2/1099-MISC) 		(E)
Reportable compensation from related organizations (W- 2/1099-MISC) 		(F)
Estimated amount of other compensation from the organization and related organizations
Individual Trustee or Director; Institutional Trustee; Officer; Key Employee; Highest compensated employee; Former;


























1b Sub-Total................MediumBullet
c Total from continuation sheets to Part VII, Section A....MediumBullet
d Total (add lines 1b and 1c)............MediumBullet 3,901,872 2,000 883,966
2
Total number of individuals (including but not limited to those listed above) who received more than $100,000 in reportable compensation from the organizationMediumBullet36
Yes
No
3
Did the organization list any former officer, director or trustee, key employee, or highest compensated employee on line 1a? If “Yes,” complete Schedule J for such individual .............
3
Yes
 
4
For any individual listed on line 1a, is the sum of reportable compensation and other compensation from the organization and related organizations greater than $150,000? If “Yes,” complete Schedule J for such individual...........................
4
Yes
 
5
Did any person listed on line 1a receive or accrue compensation from any unrelated organization or individual for services rendered to the organization? If “Yes,” complete Schedule J for such person .....
5
 
No
Section B. Independent Contractors
1
Complete this table for your five highest compensated independent contractors that received more than $100,000 of compensation from the organization.
(A)
Name and business address 		(B)
Description of services 		(C)
Compensation
HUNT - OWEN AMES & KIMBALL (SEE SCHEDULE
6720 SCOTTSDALE DR STE 300
SCOTTSDALE,AZ85253 		CONSTRUCTION SERVICES 12,393,896
BANK OF AMERICAMERRILL LYNCH
100 N TRYON ST
CHARLOTTE,NC28202 		CREDIT ENHANCEMENT FEES 3,600,486
AON RISK SERVICES CENTER INC
75 REMITTANCE DR STE 1943
CHICAGO,IL606751943 		INSURANCE 543,679
WARNER NORCROSS & JUDD
111 LYON ST 900 OLD KENT
GRAND RAPIDS,MI495032487 		LEGAL/ CONSULTING 444,669
DK SECURITY INC
5160 FALCONVIEW AVE SE
KENTWOOD,MI49512 		SECURITY SERVICES 420,458
2
Total number of independent contractors (including but not limited to those listed above) who received more than $100,000 in compensation from the organization MediumBullet24
Form 990 (2010)
Form 990 (2010)
Page 9
Part VIII
Statement of Revenue
(A)
Total revenue 		(B)
Related or
exempt
function
revenue 		(C)
Unrelated
business
revenue 		(D)
Revenue
excluded from
tax under sections
512, 513, or 514
Contributions, gifts, grants and other similar amounts 1a Federated campaigns..1a  
b Membership dues....1b  
c Fundraising events....1c  
d Related organizations...1d 47,313,999
e Government grants (contributions)1e 6,982,060
f All other contributions, gifts, grants, and
similar amounts not included above1f 		2,716,761
g Noncash contributions included in lines 1a-1f:$  
h Total. Add lines 1a-1f.......MediumBullet 57,012,820
Program Service Revenue Business Code
2a RESEARCH BILLED REV 541,700 1,522,584 235,284 1,287,300  
b
c
d
e
f All other program service revenue .        
g Total. Add lines 2a–2f........MediumBullet 1,522,584
Other Revenue 3 Investment income (including dividends, interest
and other similar amounts).....MediumBullet 159,959     159,959
4 Income from investment of tax-exempt bond proceeds..MediumBullet        
5 Royalties............MediumBullet 242,481     242,481
(i) Real (ii) Personal
6a Gross Rents 2,183,955 11,679
b Less: rental expenses 1,147,826 5,655
c Rental income or (loss) 1,036,129 6,024
d Net rental income or (loss).......MediumBullet 1,042,153 1,036,129 6,024  
(i) Securities (ii) Other
7a Gross amount from sales of assets other than inventory   767,118
b Less: cost or other basis and sales expenses   107,654
c Gain or (loss)   659,464
d Net gain or (loss)..........MediumBullet 659,464 659,464    
8a Gross income from fundraising events (not including
$  
of contributions reported on line 1c). See Part IV, line 18 ...
a  
b Less: direct expenses ...b  
c Net income or (loss) from fundraising events..MediumBullet      
9a Gross income from gaming activities.
See Part IV, line 19 ...
a  
b Less: direct expenses ...b  
c Net income or (loss) from gaming activities...MediumBullet        
10a Gross sales of inventory, less
returns and allowances .
a  
b Less: cost of goods sold ..b  
c Net income or (loss) from sales of inventory..MediumBullet        
Miscellaneous Revenue Business Code
11a REL. PARTY ADMIN SUPPO 561,000 4,274,282     4,274,282
b REIMBURSED EXPENSES 900,099 263,846     263,846
c LOSS ON INVESTMENTS 523,000 -1,491,927     -1,491,927
d All other revenue .... 3,178     3,178
e Total. Add lines 11a–11d ......MediumBullet 3,049,379
12 Total revenue. See Instructions....MediumBullet 63,688,840 1,930,877 1,293,324 3,451,819
Form 990 (2010)
Form 990 (2010)
Page 10
Part IX
Statement of Functional Expenses
Section 501(c)(3) and 501(c)(4) organizations must complete all columns. All other organizations must complete column (A) but are not required to complete columns (B), (C), and (D).
Do not include amounts reported on lines 6b,
7b, 8b, 9b, and 10b of Part VIII. 		(A)
Total expenses 		(B)
Program service expenses 		(C)
Management and general expenses 		(D)
Fundraising expenses
1 Grants and other assistance to governments and organizations in the U.S. See Part IV, line 21    
2 Grants and other assistance to individuals in the U.S. See Part IV, line 22 340,825 340,825
3 Grants and other assistance to governments, organizations, and individuals outside the U.S. See Part IV, lines 15 and 16    
4 Benefits paid to or for members    
5 Compensation of current officers, directors, trustees, and key employees .... 2,799,911 1,527,558 1,272,353  
6 Compensation not included above, to disqualified persons (as defined under section 4958(f)(1)) and persons described in section 4958(c)(3)(B) ....        
7 Other salaries and wages 18,030,691 9,952,428 7,662,767 415,496
8 Pension plan contributions (include section 401(k) and section 403(b) employer contributions) .... 1,517,854 904,745 587,999 25,110
9 Other employee benefits ....... 2,388,416 1,423,583 925,003 39,830
10 Payroll taxes ........... 1,328,510 791,961 514,902 21,647
11 Fees for services (non-employees):        
a Management ......        
b Legal ......... 1,133,197 69,871 1,063,326  
c Accounting ........... 176,968   176,968  
d Lobbying ........... 50,000   50,000  
e Professional fundraising. See Part IV, line 17..    
f Investment management fees ......        
g Other .......... 2,384,795 1,805,653 579,142  
12 Advertising and promotion .... 452,400 36,261 416,139  
13 Office expenses ....... 141,280 82,483 58,797  
14 Information technology ...... 317,986 134,979 183,007  
15 Royalties ..        
16 Occupancy ........... 2,570,936 1,985,561 585,375  
17 Travel ............ 768,754 551,253 217,501  
18 Payments of travel or entertainment expenses for any federal, state, or local public officials ......        
19 Conferences, conventions, and meetings .... 126,927 94,418 32,509  
20 Interest ........... 11,205,203 8,647,481 2,557,722  
21 Payments to affiliates .......        
22 Depreciation, depletion, and amortization ..... 10,123,630 8,209,616 1,914,014  
23 Insurance .............. 370,573 239,644 130,929  
24 Other expenses. Itemize expenses not covered above. (Expenses grouped together and labeled miscellaneous may not exceed 5% of total expenses shown on line 25 below.)
a LAB SUPPLIES & SERVICES 3,464,855 3,464,855    
b EQUIPMENT & SOFTWARE 1,944,232 1,106,860 837,372  
c OTHER SCIENTIFIC 764,424 764,424    
d SCIENTIFIC PURCHASED SE 705,358 705,358    
e RECRUITING AND RELOCATI 586,227 227,871 358,356  
f All other expenses 1,859,452 543,130 1,352,892 -36,570
25 Total functional expenses. Add lines 1 through 24f 65,553,404 43,610,818 21,477,073 465,513
26 Joint costs. Check here MediumBullet if following
SOP 98-2 (ASC 958-720). Complete this line only if the organization reported in column (B) joint costs from a combined educational campaign and fundraising solicitation 		       
Form 990 (2010)
Form 990 (2010)
Page 11
Part X Balance Sheet
(A)
Beginning of year 		(B)
End of year
Assets 1 Cash—non-interest-bearing ..........   1  
2 Savings and temporary cash investments ....... 6,671,503 2 954,773
3 Pledges and grants receivable, net ......... 2,623,400 3 1,194,099
4 Accounts receivable, net ......... 1,236,706 4 2,551,038
5 Receivables from current and former officers, directors, trustees, key employees, and highest compensated employees. Complete Part II of
Schedule L ..........   5  
6 Receivables from other disqualified persons (as defined under section 4958(f)(1)) and persons described in section 4958(c)(3)(B). Complete Part II of
Schedule L ..........   6  
7 Notes and loans receivable, net ............. 2,351,000 7 1,664,455
8 Inventories for sale or use ..............   8  
9 Prepaid expenses and deferred charges ............ 823,236 9 1,271,897
10a Land, buildings, and equipment: cost or other basis. Complete Part VI of Schedule D 10a 263,656,878
b Less: accumulated depreciation. ..... 10b 52,776,208 219,778,822 10c 210,880,670
11 Investments—publicly traded securities ..........   11  
12 Investments—other securities. See Part IV, line 11 ...... 1,887,951 12 1,367,061
13 Investments—program-related. See Part IV, line 11 .. 97,917 13 97,917
14 Intangible assets .........   14  
15 Other assets. See Part IV, line 11 ........... 18,305,890 15 50,185,978
16 Total assets. Add lines 1 through 15 (must equal line 34)... 253,776,425 16 270,167,888
Liabilities 17 Accounts payable and accrued expenses . 25,465,798 17 55,926,177
18 Grants payable ..........   18  
19 Deferred revenue .......... 1,453,448 19 1,756,331
20 Tax-exempt bond liabilities .......... 220,000,000 20 220,385,000
21 Escrow or custodial account liability. Complete Part IV of Schedule D..   21  
22 Payables to current and former officers, directors, trustees, key
employees, highest compensated employees, and disqualified
persons. Complete Part II of Schedule L..........   22  
23 Secured mortgages and notes payable to unrelated third parties ..   23  
24 Unsecured notes and loans payable to unrelated third parties ....   24  
25 Other liabilities. Complete Part X of Schedule D..... 65,771,371 25 80,017,967
26 Total liabilities. Add lines 17 through 25..... 312,690,617 26 358,085,475
Net Assets or Fund Balance Organizations that follow SFAS 117, check here MediumBullet and complete lines 27 through 29, and lines 33 and 34.
27 Unrestricted net assets ..... -39,862,048 27 -80,494,164
28 Temporarily restricted net assets ..... -19,053,644 28 -7,425,523
29 Permanently restricted net assets ..... 1,500 29 2,100
Organizations that do not follow SFAS 117, check here MediumBullet and complete lines 30 through 34.
30 Capital stock or trust principal, or current funds .....   30  
31 Paid-in or capital surplus, or land, building or equipment fund .....   31  
32 Retained earnings, endowment, accumulated income, or other funds   32  
33 Total net assets or fund balances ..... -58,914,192 33 -87,917,587
34 Total liabilities and net assets/fund balances ..... 253,776,425 34 270,167,888
Form 990 (2010)
Form 990 (2010)
Page 12
Part XI
Reconcilliation of Net Assets
Check if Schedule O contains a response to any question in this Part XI . . . . . . . . . .
1
Total revenue (must equal Part VIII, column (A), line 12) . . .
1
63,688,840
2
Total expenses (must equal Part IX, column (A), line 25) . . . . .
2
65,553,404
3
Revenue less expenses. Subtract line 2 from line 1 . . . .
3
-1,864,564
4
Net assets or fund balances at beginning of year (must equal Part X, line 33, column (A)) . .
4
-58,914,192
5
Other changes in net assets or fund balances (explain in Schedule O) . . . .
5
-27,138,831
6
Net assets or fund balances at end of year. Combine lines 3, 4, and 5 (must equal Part X, line 33, column (B)) . . . . . .
6
-87,917,587
Part XII
Financial Statements and Reporting
Check if Schedule O contains a response to any question in this Part XII . . . . . . . . . .
Yes
No
1
Accounting method used to prepare the Form 990:  
If the organization changed its method of accounting from a prior year or checked "Other," explain in
Schedule O.
2a
Were the organization’s financial statements compiled or reviewed by an independent accountant?..
2a
 
No
b
Were the organization’s financial statements audited by an independent accountant?........
2b
Yes
 
c
If “Yes,” to 2a or 2b, does the organization have a committee that assumes responsibility for oversight of the audit, review, or compilation of its financial statements and selection of an independent accountant?
If the organization changed either its oversight process or selection process during the tax year, explain in Schedule O............................
2c
Yes
 
d
If “Yes” to line 2a or 2b, check a box below to indicate whether the financial statements for the year were issued on a separate basis, consolidated basis, or both:
3a
As a result of a federal award, was the organization required to undergo an audit or audits as set forth in the Single Audit Act and OMB Circular A-133? ................
3a
Yes
 
b
If “Yes,” did the organization undergo the required audit or audits? If the organization did not undergo the required audit or audits, explain why in Schedule O and describe any steps taken to undergo such audits. ..
3b
Yes
 
Form 990 (2010)
Additional Data


Software ID:  
Software Version:  
Form 990, Special Condition Description:
Special Condition Description
SCHEDULE A
(Form 990 or 990EZ)

Department of the Treasury
Internal Revenue Service
Public Charity Status and Public Support

Complete if the organization is a section 501(c)(3) organization or a section
4947(a)(1) nonexempt charitable trust.
right arrow Attach to Form 990 or Form 990-EZ. right arrow See separate instructions.
OMB No. 1545-0047
2010
Open to Public
Inspection
Name of the organization
VAN ANDEL RESEARCH INSTITUTE
 
Employer identification number

52-2000823
Part I
Reason for Public Charity Status (All organizations must complete this part.) See instructions
The organization is not a private foundation because it is: (For lines 1 through 11, check only one box.)
1
2
3
4
SPECTRUM HEALTH,
  ,
GRAND RAPIDS, MI  
5
section 170(b)(1)(A)(iv). (Complete Part II.)
6
7
8
9
receipts from activities related to its exempt functions—subject to certain exceptions, and (2) no more than 331/3% of
its support from gross investment income and unrelated business taxable income (less section 511 tax) from businesses
acquired by the organization after June 30, 1975. See section 509(a)(2). (Complete Part III.)
10
11
e
f
g
(i) a person who directly or indirectly controls, either alone or together with persons described in (ii)
Yes
No
and (iii) below, the governing body of the the supported organization? ................
11g(i)
 
 
(ii) a family member of a person described in (i) above? ......................
11g(ii)
 
 
(iii) a 35% controlled entity of a person described in (i) or (ii) above? ................
11g(iii)
 
 
h
(i)
Name of supported organization 		(ii)
EIN 		(iii)
Type of organization (described on lines 1- 9 above or IRC section (see instructions)) 		(iv)
Is the organization in col. (i) listed in your governing document? 		(v)
Did you notify the organization in col. (i) of your support? 		(vi)
Is the organization in col. (i) organized in the U.S.? 		(vii)
Amount of support?
Yes No Yes No Yes No
Total                  

For Paperwork Reduction Act Notice, see the Instructions for Form 990.
Cat. No. 11285F
Schedule A (Form 990 or 990-EZ) 2010
Schedule A (Form 990 or 990-EZ) 2010
Page 2
Part II
Support Schedule for Organizations Described in IRC 170(b)(1)(A)(iv) and 170(b)(1)(A)(vi)
(Complete only if you checked the box on line 5, 7, or 8 of Part I or if the organization failed to qualify under Part III. If the organization fails to qualify under the tests listed below, please complete Part III.)
Section A. Public Support
Calendar year(or fiscal year beginning in) (a) 2006 (b) 2007 (c) 2008 (d) 2009 (e) 2010 (f) Total
1 Gifts, grants, contributions, and membership fees received. (Do not include any "unusual grants.") ....            
2 Tax revenues levied for the organization's benefit and either paid to or expended on its behalf.......            
3 The value of services or facilities furnished by a governmental unit to the organization without charge..            
4 Total. Add lines 1 through 3..            
5 The portion of total contributions by each person (other than a governmental unit or publicly supported organization) included on line 1 that exceeds 2% of the amount shown on line 11, column (f)..            
6 Public Support. Subtract line 5 from line 4.            
Section B. Total Support
Calendar year(or fiscal year beginning in) (a) 2006 (b) 2007 (c) 2008 (d) 2009 (e) 2010 (f) Total
7 Amounts from line 4..            
8 Gross income from interest, dividends, payments received on securities loans, rents, royalties and income from similar sources..            
9 Net income from unrelated business activities, whether or not the business is regularly carried on..            
10 Other income. (Explain in Part IV.) Do not include gain or loss from the sale of capital assets..            
11 Total support (Add lines 7 through 10).            
12
12
 
13
Section C. Computation of Public Support Percentage
14
14
 
15
15
 
16a
b
17a
b
18
Schedule A (Form 990 or 990-EZ) 2010
Schedule A (Form 990 or 990-EZ) 2010
Page 3
Part III
Support Schedule for Organizations Described in IRC 509(a)(2)
(Complete only if you checked the box on line 9 of Part I or if the organization failed to qualify under Part II. If the organization fails to qualify under the tests listed below, please complete Part II.)
Section A. Public Support
Calendar year(or fiscal year beginning in) (a) 2006 (b) 2007 (c) 2008 (d) 2009 (e) 2010 (f) Total
1 Gifts, grants, contributions, and membership fees received. (Do not include any "unusual grants.") .            
2 Gross receipts from admissions, merchandise sold or services performed, or facilities furnished in any activity that is related to the organization's tax-exempt purpose......            
3 Gross receipts from activities that are not an unrelated trade or business under section 513..            
4 Tax revenues levied for the organization's benefit and either paid to or expended on its behalf...            
5 The value of services or facilities furnished by a governmental unit to the organization without charge..            
6 Total. Add lines 1 through 5.            
7a Amounts included on lines 1, 2, and 3 received from disqualified persons...            
b Amounts included on lines 2 and 3 received from other than disqualified persons that exceed the greater of $5,000 or 1% of the amount on line 13 for the year.            
c Add lines 7a and 7b..            
8 Public Support (Subtract line 7c from line 6.)            
Section B. Total Support
Calendar year (or fiscal year beginning in) (a) 2006 (b) 2007 (c) 2008 (d) 2009 (e) 2010 (f) Total
9 Amounts from line 6...            
10a Gross income from interest, dividends, payments received on securities loans, rents, royalties and income from similar sources..            
b Unrelated business taxable income (less section 511 taxes) from businesses acquired after June 30, 1975.            
c Add lines 10a and 10b.            
11 Net income from unrelated business activities not included in line 10b, whether or not the business is regularly carried on.            
12 Other income. Do not include gain or loss from the sale of capital assets (Explain in Part IV.)            
13 Total support (Add lines 9, 10c, 11 and 12.).            
14
Section C. Computation of Public Support Percentage
15
15
 
16
16
 
Section D. Computation of Investment Income Percentage
17
17
 
18
18
 
19a
b
20
Schedule A (Form 990 or 990-EZ) 2010
Schedule A (Form 990 or 990-EZ) 2010
Page 4
Part IV
Supplemental Information. Supplemental Information. Complete this part to provide the explanation required by Part II, line 10; Part II, line 17a or 17b; or Part III, line 12. Also complete this part for any additional information. (See instructions).
Facts And Circumstances Test
 
Explanation
 
 
 
 
Schedule A (Form 990 or 990-EZ) 2010

Additional Data


Software ID:  
Software Version:  
Schedule B
(Form 990, 990-EZ,
or 990-PF)
Department of the Treasury
Internal Revenue Service
Schedule of Contributors
Arrow Bullet Attach to Form 990, 990-EZ, or 990-PF.
OMB No. 1545-0047
2010
Name of organization
VAN ANDEL RESEARCH INSTITUTE
 
Employer identification number

52-2000823
Organization type (check one):
Filers of:
Section:
Form 990 or 990-EZ





Form 990-PF




Check if your organization is covered by the General Rule or a Special Rule.  
Note. Only a section 501(c)(7), (8), or (10) organization can check boxes for both the General Rule and a Special Rule. See instructions.
General Rule—
Special Rules
......................... Arrow Bullet   $    
Caution. An Organization that is not covered by the General Rule and/or the Special Rules does not file Schedule B (Form 990,
990-EZ, or 990-PF), but it must answer “No” on Part IV, line 2 of its Form 990, or check the box in the heading of its
Form 990-EZ, or on line 2 of its Form 990-PF, to certify that it does not meet the filing requirements of Schedule B (Form 990,
990-EZ, or 990-PF).
For Paperwork Reduction Act Notice, see the Instructions
for Form 990, 990-EZ, or 990-PF.
Cat. No. 30613XSchedule B (Form 990, 990-EZ, or 990-PF) (2010)

Schedule B (Form 990, 990-EZ, or 990-PF) (2010)
Page 1 of 1 of Part I
Name of organization
VAN ANDEL RESEARCH INSTITUTE
  		Employer identification number

52-2000823
Part I
Contributors (see Instructions)
     
(a)
No.		 (b)
Name, address, and ZIP + 4		 (c)
Aggregate contributions		 (d)
Type of contribution
RESTRICTED
RESTRICTED
 

     
RESTRICTED
RESTRICTED  
RESTRICTED, RESTRICTED   RESTRICTED

$RESTRICTED




(Complete Part II if there is
a noncash contribution.)
(a)
No.		 (b)
Name, address, and ZIP + 4		 (c)
Aggregate contributions		 (d)
Type of contribution
 
 
 

     
 
   

$  




(Complete Part II if there is
a noncash contribution.)
(a)
No.		 (b)
Name, address, and ZIP + 4		 (c)
Aggregate contributions		 (d)
Type of contribution
 
 
 

     
 
   

$  




(Complete Part II if there is
a noncash contribution.)
(a)
No.		 (b)
Name, address, and ZIP + 4		 (c)
Aggregate contributions		 (d)
Type of contribution
 
 
 

     
 
   

$  




(Complete Part II if there is
a noncash contribution.)
(a)
No.		 (b)
Name, address, and ZIP + 4		 (c)
Aggregate contributions		 (d)
Type of contribution
 
 
 

     
 
   

$  




(Complete Part II if there is
a noncash contribution.)
(a)
No.		 (b)
Name, address, and ZIP + 4		 (c)
Aggregate contributions		 (d)
Type of contribution
 
 
 

     
 
   

$  




(Complete Part II if there is
a noncash contribution.)
Schedule B (Form 990, 990-EZ, or 990-PF) (2010)

Schedule B (Form 990, 990-EZ, or 990-PF) (2010)
Page 1 of 1 of Part II
Name of organization
VAN ANDEL RESEARCH INSTITUTE
  		Employer identification number

52-2000823
Part II
Noncash Property (see Instructions)
     
(a) No.
from
Part I		 (b)
Description of noncash property given		 (c)
FMV (or estimate)
(see instructions) 		(d)
Date received
 
$    
(a) No.
from
Part I		 (b)
Description of noncash property given		 (c)
FMV (or estimate)
(see instructions) 		(d)
Date received
 
$    
(a) No.
from
Part I		 (b)
Description of noncash property given		 (c)
FMV (or estimate)
(see instructions) 		(d)
Date received
 
$    
(a) No.
from
Part I		 (b)
Description of noncash property given		 (c)
FMV (or estimate)
(see instructions) 		(d)
Date received
 
$    
(a) No.
from
Part I		 (b)
Description of noncash property given		 (c)
FMV (or estimate)
(see instructions) 		(d)
Date received
 
$    
(a) No.
from
Part I		 (b)
Description of noncash property given		 (c)
FMV (or estimate)
(see instructions) 		(d)
Date received
 
$    
Schedule B (Form 990, 990-EZ, or 990-PF) (2010)

Schedule B (Form 990, 990-EZ, or 990-PF) (2010)
Page 1 of 1 of Part III
Name of organization
VAN ANDEL RESEARCH INSTITUTE
  		Employer identification number

52-2000823
Part III
Exclusively religious, charitable, etc., individual contributions to section 501(c)(7), (8), or (10) organizations
aggregating more than $1,000 for the year. (Complete columns (a) through (e) and the following line entry.)
For organizations completing Part III, enter the total of exclusively religious, charitable, etc.,
contributions of $1,000 or less for the year. (Enter this information once. See instructions.) Arrow Bullet $  
(a) No.
from
Part I		 (b)
Purpose of gift		 (c)
Use of gift		 (d)
Description of how gift is held
 
(e)
Transfer of gift
Transferee's name, address, and ZIP 4 Relationship of transferor to transferee
 
 
       
 
(a) No.
from
Part I		 (b)
Purpose of gift		 (c)
Use of gift		 (d)
Description of how gift is held
 
(e)
Transfer of gift
Transferee's name, address, and ZIP 4 Relationship of transferor to transferee
 
 
       
 
(a) No.
from
Part I		 (b)
Purpose of gift		 (c)
Use of gift		 (d)
Description of how gift is held
 
(e)
Transfer of gift
Transferee's name, address, and ZIP 4 Relationship of transferor to transferee
 
 
       
 
(a) No.
from
Part I		 (b)
Purpose of gift		 (c)
Use of gift		 (d)
Description of how gift is held
 
(e)
Transfer of gift
Transferee's name, address, and ZIP 4 Relationship of transferor to transferee
 
 
       
 
Schedule B (Form 990, 990-EZ, or 990-PF) (2010)

Additional Data


Software ID:  
Software Version:  
SCHEDULE C
(Form 990 or 990-EZ)

Department of the Treasury
Internal Revenue Service
Political Campaign and Lobbying Activities

For Organizations Exempt From Income Tax Under section 501(c) and section 527
SchCMd Bullet Complete if the organization is described below.
SchCMd Bullet Attach to Form 990 or Form 990-EZ. SchCMd Bullet See separate instructions.
OMB No. 1545-0047
2010
Open to Public
Inspection
If the organization answered “Yes,” to Form 990, Part IV, Line 3, or Form 990-EZ, Part V, line 46 (Political Campaign Activities), then
Round Bullet Section 501(c)(3) organizations: Complete Parts I-A and B. Do not complete Part I-C.
Round Bullet Section 501(c) (other than section 501(c)(3)) organizations: Complete Parts I-A and C below. Do not complete Part I-B.
Round Bullet Section 527 organizations: Complete Part I-A only.
If the organization answered “Yes,” to Form 990, Part IV, Line 4, or Form 990-EZ, Part VI, line 47 (Lobbying Activities), then
Round Bullet Section 501(c)(3) organizations that have filed Form 5768 (election under section 501(h)) Complete Part II-A. Do not complete Part II-B.
Round Bullet Section 501(c)(3) organizations that have NOT filed Form 5768 (election under section 501(h)): Complete Part II-B. Do not complete Part II-A.
If the organization answered “Yes,” to Form 990, Part IV, Line 5 (Proxy Tax) or Form 990-EZ, Part V, line 35a (Proxy Tax), then
Round Bullet Section 501(c)(4), (5), or (6) organizations: Complete Part III.
Name of the organization
VAN ANDEL RESEARCH INSTITUTE
 
Employer identification number

52-2000823
Part I-A
Complete if the organization is exempt under section 501(c) or is a section 527 organization.

1
Provide a description of the organization's direct and indirect political campaign activities on behalf of or in opposition to candidates for public office in Part IV.
2
Political expenditures ....................................SchCMd Bullet
$  
3
Volunteer hours ........................................
 

Part I-B
Complete if the organization is exempt under section 501(c)(3).
1
Enter the amount of any excise tax incurred by the organization under section 4955 .........SchCMd Bullet
$  
2
Enter the amount of any excise tax incurred by organization managers under section 4955 ......SchCMd Bullet
$  
3
If the organization incurred a section 4955 tax, did it file Form 4720 for this year? ..............
4a
Was a correction made? .........................................
b
If "Yes," describe in Part IV.
Part I-C
Complete if the organization is exempt under section 501(c) except section 501(c)(3).
1
Enter the amount directly expended by the filing organization for section 527 exempt function activities SchCMd Bullet
$  
2
Enter the amount of the filing organization's funds contributed to other organizations for section 527 exempt funtion activities ....................................SchCMd Bullet

$  
3
Total exempt function expenditures. Add lines 1 and 2. Enter here and on Form 1120-POL, line 17b..SchCMd Bullet

$  
4
Did the filing organization file Form 1120-POL for this year? ..........................
5
Enter the names, addresses and employer identification number (EIN) of all section 527 political organizations to which the filing
organization made payments. For each organization listed, enter the amount paid from the filing organization’s funds. Also enter the amount of political contributions received that were promptly and directly delivered to a separate political organization, such as a separate segregated fund or a political action committee (PAC). If additional space is needed, provide information in Part IV.
(a) Name (b) Address (c) EIN (d) Amount paid from filing organization's funds. If none, enter -0-. (e) Amount of political contributions received and promptly and directly delivered to a separate political organization. If none, enter -0-.










For Privacy Act and Paperwork Reduction Act Notice, see the instructions for Form 990.
Cat. No. 50084S
Schedule C (Form 990 or 990-EZ) 2010

Schedule C (Form 990 or 990-EZ) 2010
Page 2
Part II-A
Complete if the organization is exempt under section 501(c)(3) and filed Form 5768 (election under section 501(h)).
A Check
B Check
Limits on Lobbying Expenditures
(The term "expenditures" means amounts paid or incurred.) 		(a) Filing
Organization's
Totals 		(b) Affiliated Group
Totals
1a Total lobbying expenditures to influence public opinion (grass roots lobbying) ......    
b Total lobbying expenditures to influence a legislative body (direct lobbying) .......    
c Total lobbying expenditures (add lines 1a and 1b) ...................    
d Other exempt purpose expenditures ........................    
e Total exempt purpose expenditures (add lines 1c and 1d) ...............    
f Lobbying nontaxable amount. Enter the amount from the following table in both
columns.		    
  If the amount on line 1e, column (a) or (b) is:The lobbying nontaxable amount is:    
  Not over $500,00020% of the amount on line 1e.    
  Over $500,000 but not over $1,000,000$100,000 plus 15% of the excess over $500,000.    
  Over $1,000,000 but not over $1,500,000$175,000 plus 10% of the excess over $1,000,000.    
  Over $1,500,000 but not over $17,000,000$225,000 plus 5% of the excess over $1,500,000.    
  Over $17,000,000$1,000,000.    
       
g Grassroots nontaxable amount (enter 25% of line 1f) .................    
h Subtract line 1g from line 1a. If zero or less, enter -0-. ................    
i Subtract line 1f from line 1c. If zero or less, enter -0-. ................    
j If there is an amount other than zero on either line 1h or line 1i, did the organization file Form 4720 reporting
section 4911 tax for this year? ......................................

4-Year Averaging Period Under Section 501(h)
(Some organizations that made a section 501(h) election do not have to complete all of the five
columns below. See the instructions for lines 2a through 2f on page 4.)
Lobbying Expenditures During 4-Year Averaging Period
  Calendar year (or fiscal year
beginning in) 		(a) 2007 (b) 2008 (c) 2009 (d) 2010 (e) Total
             
2a Lobbying non-taxable amount          
             
b Lobbying ceiling amount
(150% of line 2a, column(e)) 		         
             
c Total lobbying expenditures          
             
d Grassroots non-taxable amount          
             
e Grassroots ceiling amount
(150% of line 2d, column (e))		          
             
f Grassroots lobbying expenditures          
Schedule C (Form 990 or 990-EZ) 2010


Schedule C (Form 990 or 990-EZ) 2010
Page 3
Part II-B
Complete if the organization is exempt under section 501(c)(3) and has NOT filed Form 5768 (election under section 501(h)).
(a)
Yes
No
(b)
Amount
1
During the year, did the filing organization attempt to influence foreign, national, state or local legislation, including any attempt to influence public opinion on a legislative matter or referendum, through the use of:
a
Volunteers? .........................................
 
No
b
Paid staff or management (include compensation in expenses reported on lines 1c through 1i)? ....
Yes
 
c
Media advertisements? ....................................
 
No
 
d
Mailings to members, legislators, or the public? .........................
 
No
 
e
Publications, or published or broadcast statements? .......................
 
No
 
f
Grants to other organizations for lobbying purposes? .......................
 
No
 
g
Direct contact with legislators, their staffs, government officials, or a legislative body? ........
Yes
 
50,000
h
Rallies, demonstrations, seminars, conventions, speeches, lectures, or any similar means? ......
 
No
 
i
Other activities? If "Yes," describe in Part IV ..........................
 
No
 
j
Total. lines 1c through 1i ...................................
50,000
2a
Did the activities in line 1 cause the organization to be not described in section 501(c)(3)? .....
 
No
b
If "Yes," enter the amount of any tax incurred under section 4912 .................
 
c
If "Yes," enter the amount of any tax incurred by organization managers under section 4912 .....
 
d
If the filing organization incurred a section 4912 tax, did it file Form 4720 for this year? .......
 
 
Part III-A
Complete if the organization is exempt under section 501(c)(4), section 501(c)(5), or section 501(c)(6).
Yes
No
1
Were substantially all (90% or more) dues received nondeductible by members? ................
1
 
 
2
Did the organization make only in-house lobbying expenditures of $2,000 or less? ................
2
 
 
3
Did the organization agree to carryover lobbying and political expenditures from the prior year? ..........
3
 
 
Part III-B
Complete if the organization is exempt under section 501(c)(4), section 501(c)(5), or section 501(c)(6) if BOTH Part III-A, lines 1 and 2 are answered “No” OR if Part III-A, line 3 is answered “Yes”.
1
Dues, assessments and similar amounts from members .....................
1
 
2
Section 162(e) non-deductible lobbying and political expenditures (do not include amounts of political
expenses for which the section 527(f) tax was paid).
a
Current year .........................................
2a
 
b
Carryover from last year ....................................
2b
 
c
Total ...........................................
2c
 
3
Aggregate amount reported in section 6033(e)(1)(A) notices of nondeductible section 162(e) dues .
3
 
4
If notices were sent and the amount on line 2c exceeds the amount on line 3, what portion of the excess does the organization agree to carryover to the reasonable estimate of nondeductible lobbying and political expenditure next year? ................................
4
 
5
Taxable amount of lobbying and political expenditures (see instructions) ..............
5
 
Part IV
Supplemental Information
Complete this part to provide the descriptions required for Part l-A, line 1; Part l-B, line 4; Part l-C, line 5; and Part ll-B, line 1i.
Also, complete this part for any additional information.
Identifier Return Reference Explanation
PART IV, SUPPLEMENTAL INFORMATION:   PAID MANAGEMENT WAS ONLY UTILIZED TO MANAGE RELATIONSHIPS WITH OUTSIDE CONSULTANTS AND DID NOT PARTICIPATE IN DIRECT LOBBYING. THEREFORE, NO COMPENSATION EXPENSE HAS BEEN ALLOCATED TO LOBBYING EXPENSE.
Schedule C (Form 990 or 990EZ) 2010

Additional Data


Software ID:  
Software Version:  

SCHEDULE D
(Form 990)
Department of the Treasury
Internal Revenue Service
Supplemental Financial Statements
SchDMd Bullet Complete if the organization answered "Yes," to Form 990,
Part IV, line 6, 7, 8, 9, 10, 11, or 12.
SchDMd Bullet Attach to Form 990. SchDMd Bullet See separate instructions.
OMB No. 1545-0047
2010
Open to Public Inspection
Name of the organization
VAN ANDEL RESEARCH INSTITUTE
 
Employer identification number

52-2000823
Part I
Organizations Maintaining Donor Advised Funds or Other Similar Funds or Accounts. Complete if the organization answered "Yes" to Form 990, Part IV, line 6.
(a) Donor advised funds (b) Funds and other accounts
1 Total number at end of year .......    
2 Aggregate contributions to (during year) ...    
3 Aggregate grants from (during year) ...    
4 Aggregate value at end of year .......    
5
Did the organization inform all donors and donor advisors in writing that the assets held in donor advised
funds are the organization's property, subject to the organization's exclusive legal control? ............
6
Did the organization inform all grantees, donors, and donor advisors in writing that grant funds may be
used only for charitable purposes and not for the benefit of the donor or donor advisor, or for any other purpose conferring impermissible private benefit. ...................................
Part II
Conservation Easements. Complete if the organization answered "Yes" to Form 990, Part IV, line 7.
1
Purpose(s) of conservation easements held by the organization (check all that apply).
2
Complete lines 2a–2d if the organization held a qualified conservation contribution in the form of a conservation easement on the last day of the tax year.
Held at the End of the Year
a Total number of conservation easements ....................... 2a  
b Total acreage restricted by conservation easements .................. 2b  
c Number of conservation easements on a certified historic structure included in (a) ..... 2c  
d Number of conservation easements included in (c) acquired after 8/17/06 ........ 2d  
3
Number of conservation easements modified, transferred, released, extinguished, or terminated by the organization during
the taxable year SchDMd Bullet  
4
Number of states where property subject to conservation easement is located SchDMd Bullet  
5
Does the organization have a written policy regarding the periodic monitoring, inspection, handling of violations, and
enforcement of the conservation easements it holds? .............................
6
Staff and volunteer hours devoted to monitoring, inspecting and enforcing conservation easements during the year SchDMd Bullet  
7
Amount of expenses incurred in monitoring, inspecting, and enforcing conservation easements during the year SchDMd Bullet $  
8
Does each conservation easement reported on line 2(d) above satisfy the requirements of section
170(h)(4)(B)(i) and 170(h)(4)(B)(ii)? ....................................
9
In Part XIV, describe how the organization reports conservation easements in its revenue and expense statement, and
balance sheet, and include, if applicable, the text of the footnote to the organization’s financial statements that describes
the organization’s accounting for conservation easements.
Part III
Organizations Maintaining Collections of Art, Historical Treasures, or Other Similar Assets.
Complete if the organization answered "Yes" to Form 990, Part IV, line 8.
1a
If the organization elected, as permitted under SFAS 116, not to report in its revenue statement and balance sheet works of
art, historical treasures, or other similar assets held for public exhibition, education or research in furtherance of public service,
provide, in Part XIV, the text of the footnote to its financial statements that describes these items.
b
If the organization elected, as permitted under SFAS 116, to report in its revenue statement and balance sheet works of art,
historical treasures, or other similar assets held for public exhibition, education, or research in furtherance of public service,
provide the following amounts relating to these items:
(i)
Revenues included in Form 990, Part VIII, line 1 ........................SchDMd Bullet $  
(ii)
Assets included in Form 990, Part X ..............................SchDMd Bullet $ 435,037
2
If the organization received or held works of art, historical treasures, or other similar assets for financial gain, provide the
following amounts required to be reported under SFAS 116 relating to these items:
a
Revenues included in Form 990, Part VIII, line 1 ..........................SchDMd Bullet $  
b
Assets included in Form 990, Part X ...............................SchDMd Bullet $  
For Privacy Act and Paperwork Reduction Act Notice, see the Intructions for Form 990
Cat. No. 52283D
Schedule D (Form 990) 2010

Schedule D (Form 990) 2010
Page 2
Part III
Organizations Maintaining Collections of Art, Historical Treasures, or Other Similar Assets (continued)
3
Using the organization’s accession and other records, check any of the following that are a significant use of its collection
items (check all that apply):
a
d
b
e
 
c
4
Provide a description of the organization’s collections and explain how they further the organization’s exempt purpose in
Part XIV.
5
During the year, did the organization solicit or receive donations of art, historical treasures or other similar
assets to be sold to raise funds rather than to be maintained as part of the organization’s collection?........
Part IV
Escrow and Custodial Arrangements. Complete if the organization answered "Yes" to Form 990,
Part IV, line 9, or reported an amount on Form 990, Part X, line 21.
1a
Is the organization an agent, trustee, custodian or other intermediary for contributions or other assets not
included on Form 990, Part X? ....................................
b
If "Yes," explain the arrangement in Part XIV and complete the following table:
Amount
c Beginning balance ................................. 1c  
d Additions during the year .............................. 1d  
e Distributions during the year ............................. 1e  
f Ending balance ................................... 1f  
2a
Did the organization include an amount on Form 990, Part X, line 21? .....................
b
If “Yes,” explain the arrangement in Part XIV.
Part V
Endowment Funds. Complete if the organization answered "Yes" to Form 990, Part IV, line 10.
(a)Current Year (b)Prior Year (c)Two Years Back (d)Three Years Back (e)Four Years Back
1a Beginning of year balance ....      
b Contributions ........      
c Investment earnings or losses ...      
d Grants or scholarships .....      
e Other expenditures for facilities
and programs ........ 		     
f Administrative expenses ....      
g End of year balance ......      
2
Provide the estimated percentage of the year end balance held as:
a
Board designated or quasi-endowment: SchDMd Bullet  
b
Permanent endowment: SchDMd Bullet  
c
Term endowment: SchDMd Bullet  
3a
Are there endowment funds not in the possession of the organization that are held and administered for the
organization by:

Yes
No
(i) unrelated organizations ........................
3a(i)
 
 
(ii) related organizations ........................
3a(ii)
Yes
 
b
If "Yes" to 3a(ii), are the related organizations listed as required on Schedule R? .........
3b
Yes
 
4
Describe in Part XIV the intended uses of the organization's endowment funds.
Part VI
Investments—Land, Buildings, and Equipment. See Form 990, Part X, line 10.
Description of investment (a) Cost or other basis (investment) (b)Cost or other basis (other) (c) Accumulated depreciation (d) Book value
1a Land .................   5,288,315 5,288,315
b Buildings ................   218,665,823 26,474,773 192,191,050
c Leasehold improvements ............        
d Equipment ................   38,310,415 26,272,369 12,038,046
e Other .................   1,392,325 29,066 1,363,259
Total. Add lines 1a-1e. (Column (d) should equal Form 990, Part X, column (B), line 10(c).)........SchDMdBullet 210,880,670
Schedule D (Form 990) 2010

Schedule D (Form 990) 2010
Page 3
Part VII
Investments—Other Securities. See Form 990, Part X, line 12.
(a) Description of security or category
(including name of security)		 (b)Book value (c) Method of valuation:
Cost or end-of-year market value
(1)Financial derivatives    
(2)Closely-held equity interests    
Other








Total. (Column (b) should equal Form 990, Part X, col.(B) line 12.)Small Bullet  
Part VIII
Investments—Program Related. See Form 990, Part X, line 13.
(a) Description of investment type (b) Book value (c) Method of valuation:
Cost or end-of-year market value








Total. (Column (b) should equal Form 990, Part X, col.(B) line 13.)Small Bullet  
Part IX
Other Assets. See Form 990, Part X, line 15.
(a) Description (b) Book value
(1) BOND ISSUANCE COSTS NET OF ACCUMULATED AMORTIZATION 1,565,978
(2) PLEDGED SECURITIES 48,620,000







Total. (Column (b) should equal Form 990, Part X, col.(B) line 15.)...........Small Bullet 50,185,978
Part X
Other Liabilities. See Form 990, Part X, line 25.
1.(a) Description of Liability (b) Amount
Federal Income Taxes  
ACCRUED POSTRETIREMENT BENEFIT OBLIGATION 1,364,665
UNREALIZED LOSS ON BOND SWAP 62,909,361
MSU MED SCHOOL - CONTRIBUTION PAYABLE 7,696,315
CAPITAL LEASE 47,626
TGEN - CONTRIBUTION PAYABLE 8,000,000




Total. (Column (b) should equal Form 990, Part X, col.(B) line 25.)Small Bullet 80,017,967
2. Fin 48 (ASC 740) Footnote. In Part XIV, provide the text of the footnote to the organization's financial statements that reports the organization's liability for uncertain tax positions under FIN 48 (ASC740).
Schedule D (Form 990) 2010

Schedule D (Form 990) 2010
Page 4
Part XI Reconciliation of Change in Net Assets from Form 990 to Financial Statements
1 Total revenue (Form 990, Part VIII, column (A), line 12) .................... 1 63,688,840
2 Total expenses (Form 990, Part IX, column (A), line 25) ..................... 2 65,553,404
3 Excess or (deficit) for the year. Subtract line 2 from line 1 ............. 3 -1,864,564
4 Net unrealized gains (losses) on investments .......................... 4 -251,644
5 Donated services and use of facilities ............................. 5  
6 Investment expenses ................................... 6  
7 Prior period adjustments .................................. 7  
8 Other (Describe in Part XIV) ................................. 8 -26,887,187
9 Total adjustments (net). Add lines 4 - 8 ............................. 9 -27,138,831
10 Excess or (deficit) for the year per financial statements. Combine lines 3 and 9 ......... 10 -29,003,395
Part XII Reconciliation of Revenue per Audited Financial Statements With Revenue per Return
1 Total revenue, gains, and other support per audited financial statements ....... 1 59,181,889
2 Amounts included on line 1 but not on Form 990, Part VIII, line 12:
a Net unrealized gains on investments .......... 2a -251,644
b Donated services and use of facilities ......... 2b  
c Recoveries of prior year grants ........... 2c  
d Other (Describe in Part XIV): ............ 2d 18,975
e Add lines 2a through 2d ..................... 2e -232,669
3 Subtract line 2e from line 1..................... 3 59,414,558
4 Amounts included on Form 990, Part VIII, line 12, but not on line 1:
a Investment expenses not included on Form 990, Part VIII, line 7b . 4a  
b Other (Describe in Part XIV): ........... 4b 4,274,282
c Add lines 4a and 4b....................... 4c 4,274,282
5 Total Revenue. Add lines 3 and 4c. (This should equal Form 990, Part I, line 12.) ...... 5 63,688,840
Part XIII Reconciliation of Expenses per Audited Financial Statements With Expenses per Return
1 Total expenses and losses per audited financial statements ............. 1 88,185,284
2 Amounts included on line 1 but not on Form 990, Part IX, line 25:
a Donated services and use of facilities .......... 2a  
b Prior year adjustments .............. 2b  
c Other losses ................ 2c  
d Other (Describe in Part XIV): ............ 2d 26,906,162
e Add lines 2a through 2d...................... 2e 26,906,162
3 Subtract line 2e from line 1..................... 3 61,279,122
4 Amounts included on Form 990, Part IX, line 25, but not on line 1:
a Investment expenses not included on Form 990, Part VIII, line 7b .. 4a  
b Other (Describe in Part XIV): ............ 4b 4,274,282
c Add lines 4a and 4b....................... 4c 4,274,282
5 Total expenses. Add lines 3 and 4c. (This should equal Form 990, Part I, line 18.) ...... 5 65,553,404
Part XIV
Supplemental Information
Complete this part to provide the descriptions required for Part II, lines 3, 5, and 9; Part III, lines 1a and 4; Part lV, lines 1b and 2b;
Part V, line 4; Part X; Part XI, line 8; Part XII, lines 2d and 4b; and Part XIII, lines 2d and 4b. Also complete this part to provide any additional information.
Identifier Return Reference Explanation
  PART III, LINE 4: THE GLASS CHIHULY SCULPTURE IS A UNIQUE, ONE-OF-A-KIND CHANDELIER REMINISCENT OF THE DNA DOUBLE HELIX. THE CHANDELIER, WHICH IS PLACED IN THE RECEPTION AREA, PROVIDES MOTIVATION AND INSPIRATION AS SCIENTISTS ARE DRIVEN TO UNDERSTAND THE GENETIC BASIS OF DISEASES IN THEIR PURSUIT OF CURES AND OTHER THERAPIES.
DESCRIPTION OF INTENDED USE OF ENDOWMENT FUNDS: PART V, LINE 4: TO SUPPORT THE CORE RESEARCH OF VARI BY SUPPLYING A STEADY SOURCE OF INCOME FOR ITS OPERATING BUDGETS.
    PART X: IN JUNE 2006, FASB ISSUED ASC 740, INCOME TAXES (FORMERLY FASB INTERPRETATION (FIN) NO. 48, ACCOUNTING FOR UNCERTAINTY IN INCOME TAXES - AN INTERPRETATION OF FASB STATEMENT NO. 109). ASC 740 PRESCRIBES A RECOGNITION THRESHOLD AND MEASUREMENT ATTRIBUTE FOR THE FINANCIAL STATEMENT RECOGNITION AND MEASUREMENT OF A TAX POSITION TAKEN OR EXPECTED TO BE TAKEN IN A TAX RETURN. ASC 740 ALSO PROVIDES GUIDANCE ON DERECOGNITION, CLASSIFICATION, INTEREST AND PENALTIES, ACCOUNTING FOR INTERIM PERIODS, DISCLOSURE, AND TRANSITION. ASC 740 IS EFFECTIVE FOR FISCAL YEARS BEGINNING AFTER DECEMBER 15, 2008. THIS STANDARD WAS ADOPTED FOR FISCAL YEAR ENDED NOVEMBER 30, 2010. THERE WAS NO MATERIAL IMPACT ON THE CONSOLIDATED FINANCIAL STATEMENTS FOR THE YEAR ENDED NOVEMBER 30, 2011.
    PART XI, LINE 8: NET LOSS RELATED TO THE INTEREST RATE SWAP. PART XII, LINE 2D: RECLASS OF TMS COST OF GOODS SOLD TO PRESENT ON STATEMENT OF REVENUE RATHER THAN STATEMENT OF FUNCTIONAL EXPENSES. PART XIII, LINE 2D: INCLUDES BOTH THE NET LOSS RELATED TO THE INTEREST RATE SWAP AND RECLASS OF TMS COST OF GOODS SOLD TO PRESENT ON STATEMENT OF REVENUE RATHER THAN STATEMENT OF FUNCTIONAL EXPENSES.
    PART XII AND XIII, LINE 4B: EXPENSE ALLOCATIONS
    PART V - ALL ENDOWMENT FUNDS ARE HELD AT THE VAN ANDEL INSTITUTE (A RELATED ORGANIZATION).
Schedule D (Form 990) 2010

Additional Data


Software ID:  
Software Version:  




SCHEDULE F
(Form 990)

Department of the Treasury
Internal Revenue Service
Statement of Activities Outside the United States
Right pointing arrow large image Complete if the organization answered "Yes" to Form 990,
Part IV, line 14b, 15, or 16.
Right pointing arrow large image Attach to Form 990. Right pointing arrow large image See separate instructions.
OMB No. 1545-0047
2010
Open to Public Inspection
Name of the organization
VAN ANDEL RESEARCH INSTITUTE
 
Employer identification number

52-2000823
Part I
General Information on Activities Outside the United States. Complete if the organization answered
“Yes” to Form 990, Part IV, line 14b.
1
For grantmakers. Does the organization maintain records to substantiate the amount of the grants or
assistance, the grantees' eligibility for the grants or assistance, and the selection criteria used to award
the grants or assistance? ...................................
2
For grantmakers. Describe in Part V the organization’s procedures for monitoring the use of grant funds outside the
United States.
3
Activites per Region. (Use Part V if additional space is needed.)
(a) Region (b) Number of offices in the region (c) Number of employees or agents in region or independent contractors (d) Activities conducted in region (by type) (e.g., fundraising, program services, investments, grants to recipients located in the region) (e) If activity listed in (d) is a program service, describe specific type of
service(s) in region		 (f) Total
expenditures for region/investments
in region
EAST ASIA & THE PACIFIC 0 2 PROGRAM SERVICES RESEARCH COLLABORATION - RESEARCH SERVICES 429,197
           
           
           
           
           
           
           
           
           
           
           
           
           
           
           
           
3a Sub-total .....   2 429,197
b Total from continuation sheets to Part I ...   0 0
c Totals (add lines 3a and 3b)   2 429,197
For Privacy Act and Paperwork Reduction Act Notice, see the Instructions for Form 990.Cat. No. 50082W Schedule F (Form 990) 2010
Schedule F (Form 990) 2010
Page 2
Part II
Grants and Other Assistance to Organizations or Entities Outside the United States. Complete if the organization answered "Yes" to Form 990,
Part IV, line 15, for any recipient who received more than $5,000. Check this box if no one recipient received more than $5,000 ........ MediumBullet
Use Part V if additional space is needed.
1 (a) Name of organization (b) IRS code section
and EIN (if applicable)		 (c) Region (d) Purpose of
grant 		(e) Amount of
cash grant 		(f) Manner of
cash
disbursement 		(g) Amount of
of non-cash
assistance 		(h) Description
of non-cash
assistance 		(i) Method of
valuation
(book, FMV,
appraisal, other)
             
             
             
             
             
             
             
             
             
             
             
             
             
             
             
             
2
Enter total number of recipient organizations listed above that are recognized as charities by the foreign country, recognized as tax-exempt by the IRS, or for which the grantee or counsel has provided a section 501(c)(3) equivalency letter .....MediumBullet
 
3
Enter total number of other organizations or entities ........................MediumBullet
 
Schedule F (Form 990) 2010
Schedule F (Form 990) 2010Page 3
Part III
Grants and Other Assistance to Individuals Outside the United States. Complete if the organization answered "Yes" to Form 990, Part IV, line 16.
Use Part V if additional space is needed.
(a) Type of grant or assistance (b) Region (c) Number of recipients (d) Amount of
cash grant 		(e) Manner of cash
disbursement 		(f) Amount of
non-cash
assistance 		(g) Description
of non-cash
assistance 		(h) Method of
valuation
(book, FMV,
appraisal, other)
               
               
               
               
               
               
               
               
               
               
               
               
               
               
               
               
               
               
Schedule F (Form 990) 2010
Schedule F (Form 990) 2010
Page 4
Part IV
Foreign Forms
1 Was the organization a U.S. transferor of property to a foreign corporation during the tax year? If "Yes," the organization may be required to file Form 926 (see instructions for Form 926).................
2 Did the organization have an interest in a foreign trust during the tax year? If " Yes," the organization may be required to file Form 3520 and/or Form 3520-A. (see instructions for Forms 3520 and 3520-A)..........
3 Did the organization have an ownership interest in a foreign corporation during the tax year? If "Yes," the organization may be required to file Form 5471, Information Return of U.S. Persons with respect to Certain Foreign Corporations. (see instructions for Form 5471)..............................
4 Was the organization a direct or indirect shareholder of a passive foreign investment company or a qualified electing fund during the tax year? If "Yes," the organization may be required to file Form 8621, Return by a Shareholder of a Passive Foreign Investment Company or Qualified Electing Fund. (see instructions for Form 8621)
5 Did the organization have an ownership interest in a foreign partnership during the tax year? If "Yes," the organization may be required to file Form 8865, Return of U.S. Persons with respect to Certain Foreign Partnerships. (see instructions for Form 8865)....................................
6 Did the organization have any operations in or related to any boycotting countries during the tax year? If "Yes," the organization may be required to file Form 5713, International Boycott Report (see instructions for Form 5713)................................................
Schedule F (Form 990) 2010
Schedule F (Form 990) 2010
Page 5
Part V
Supplemental Information
Complete this part to provide the information (see instructions) required in Part I, line 2, and any additional information.
Identifier ReturnReference Explanation
     
     
     
     
     
     
     
     
     
     
     
     
     
     
     
     
     
     
     
     
     
     
Schedule F (Form 990) 2010
Additional Data


Software ID:  
Software Version:  



Schedule I
(Form 990)
Department of the Treasury
Internal Revenue Service
Grants and Other Assistance to Organizations,
Governments and Individuals in the United States
Complete if the organization answered "Yes," to Form 990, Part IV, line 21 or 22.
lBullet Attach to Form 990
OMB No. 1545-0047
2010
Open to Public
Inspection
Name of the organization
VAN ANDEL RESEARCH INSTITUTE
 
Employer identification number
52-2000823
Part I
General Information on Grants and Assistance
1
Does the organization maintain records to substantiate the amount of the grants or assistance, the grantees' eligibility for the grants or assistance, and
the selection criteria used to award the grants or assistance? ....................................
2
Describe in Part IV the organization's procedures for monitoring the use of grant funds in the United States.
Part II
Grants and Other Assistance to Governments and Organizations in the United States. Complete if the organization answered "Yes" to
Form 990, Part IV, line 21 for any recipient that received more than $5,000. Check this box if no one recipient received more than $5,000. Use
Part IV and Schedule I-1 (Form 990) if additional space is needed ......................... lBullet
(a) Name and address of organization
or government		 (b) EIN (c) IRC Code section
if applicable		 (d) Amount of cash grant (e) Amount of non-cash
assistance		 (f) Method of valuation
(book, FMV, appraisal,
other)		 (g) Description of
non-cash assistance		 (h) Purpose of grant
or assistance






















2
Enter total number of section 501(c)(3) and government organizations ......................... Bullet Image
 
3
Enter total number of other organizations ................................ . Bullet Image
 
For Privacy Act and Paperwork Reduction Act Notice, see the Instructions for Form 990.
Cat. No. 50055P
Schedule I (Form 990) 2010

Schedule I (Form 990) 2010
Page 2
Part III
Grants and Other Assistance to Individuals in the United States. Complete if the organization answered "Yes" to Form 990, Part IV, line 22.
Use Schedule I-1 (Form 990) if additional space is needed.
(a)Type of grant or assistance (b)Number of
recipients		 (c)Amount of
cash grant		 (d)Amount of
non-cash assistance		 (e)Method of valuation (book,
FMV, appraisal, other)		 (f)Description of non-cash assistance
(1) GRADUATE STUDENT STIPENDS FOR VAN ANDEL GRADUATE SCHOOL AND MICHIGAN STATE UNIVERSITY STUDENTS 8 235,354 10,500 TUITION PAID  
(2) FOREIGN NATIONAL STUDENT STIPENDS 14 94,971      











Part IV
Supplemental Information. Complete this part to provide the information required in Part I, line 2, and any other additional information.
Identifier Return Reference Explanation
OTHER INFORMATION: PART IV: SCHEDULE I, PART I, LINE 2: FUNDS PROVIDED TO THE RESEARCH STUDENTS ARE CONTINUALLY MONITORED TO ENSURE THAT ALL FUNDS ARE USED FOR MISSION-DRIVEN PURPOSES. STIPENDS ARE PROVIDED DIRECTLY TO THE STUDENTS FOR LIVING ASSISTANCE.
Schedule I (Form 990) 2010


Additional Data


Software ID:  
Software Version:  


Schedule J
(Form 990)
Department of the Treasury
Internal Revenue Service
Compensation Information
For certain Officers, Directors, Trustees, Key Employees, and Highest
Compensated Employees
SchJMediumBullet Complete if the organization answered "Yes" to Form 990,
Part IV, question 23.
SchJMediumBullet Attach to Form 990. SchJMediumBullet See separate instructions.
OMB No. 1545-0047
2010
Open to Public Inspection
Name of the organization
VAN ANDEL RESEARCH INSTITUTE
 
Employer identification number

52-2000823
Part I
Questions Regarding Compensation
Yes
No
1a
Check the appropiate box(es) if the organization provided any of the following to or for a person listed in Form
990, Part VII, Section A, line 1a. Complete Part III to provide any relevant information regarding these items.
b
If any of the boxes in line 1a are checked, did the organization follow a written policy regarding payment or reimbursement orprovision of all the expenses described above? If "No," complete Part III to explain....
1b
 
No
2
Did the organization require substantiation prior to reimbursing or allowing expenses incurred by all
officers, directors, trustees, and the CEO/Executive Director, regarding the items checked in line 1a? ....
2
Yes
 
3
Indicate which, if any, of the following the organization uses to establish the compensation of the
organization's CEO/Executive Director. Check all that apply.
4
During the year, did any person listed in Form 990, Part VII, Section A, line 1a with respect to the filing organization or a related organization:
a
Receive a severance payment or change-of-control payment? ...............
4a
Yes
 
b
Participate in, or receive payment from, a supplemental nonqualified retirement plan? ........
4b
Yes
 
c
Participate in, or receive payment from, an equity-based compensation arrangement? ........
4c
 
No
If "Yes" to any of lines 4a-c, list the persons and provide the applicable amounts for each item in Part III.
Only 501(c)(3) and 501(c)(4) organizations only must complete lines 5-9.
5
For persons listed in form 990, Part VII, Section A, line 1a, did the organization pay or accrue any
compensation contingent on the revenues of:
a
The organization? ...........................
5a
 
No
b
Any related organization? .........................
5b
 
No
If "Yes," to line 5a or 5b, describe in Part III.
6
For persons listed in form 990, Part VII, Section A, line 1a, did the organization pay or accrue any
compensation contingent on the net earnings of:
a
The organization? ...........................
6a
 
No
b
Any related organization? .........................
6b
 
No
If "Yes," to line 6a or 6b, describe in Part III.
7
For persons listed in Form 990, Part VII, Section A, line 1a, did the organization provide any non-fixed
payments not described in lines 5 and 6? If "Yes," describe in Part III ............
7
 
No
8
Were any amounts reported in Form 990, Part VII, paid or accured pursuant to a contract that was
subject to the initial contract exception described in Regs. section 53.4958-4(a)(3)? If "Yes," describe
in Part III .............................
8
 
No
9
If "Yes" to line 8, did the organization also follow the rebuttable presumption procedure described in Regulations section 53.4958-6(c)? .........................
9
 
 
For Privacy Act and Paperwork Reduction Act Notice, see the Intructions for Form 990
Cat. No. 50053T
Schedule J (Form 990) 2010

Schedule J (Form 990) 2010
Page 2
Part II
Officers, Directors, Trustees, Key Employees, and Highest Compensated Employees. Use Schedule J-1 if additional space needed.
For each individual whose compensation must be reported in Schedule J, report compensation from the organization on row (i) and from related organizations, described in the
instructions on row (ii). Do not list any individuals that are not listed on Form 990, Part VII.

Note. The sum of columns (B)(i)-(iii) must equal the applicable column (D) or column (E) amounts on Form 990, Part VII, line 1a.
(A) Name (B) Breakdown of W-2 and/or 1099-MISC compensation (C) Retirement and other deferred compensation (D) Nontaxable
benefits		 (E) Total of columns
(B)(i)-(D) 		(F) Compensation
reported in prior
Form 990 or
Form 990-EZ
(i) Base compensation (ii) Bonus & incentive compensation (iii) Other reportable compensation
(1) DAVID VAN ANDEL (i)
(ii)		 300,014
0 		89,284
0 		22,952
0 		129,426
0 		539
0 		542,215
0 		0
0
(2) GEORGE VANDE WOUDE (i)
(ii)		 281,791
0 		15,000
0 		28,972
0 		43,022
0 		1,323
0 		370,108
0 		0
0
(3) DR JEFFREY TRENT (i)
(ii)		 853,335
0 		130,000
0 		60,070
0 		291,278
0 		11,752
0 		1,346,435
0 		0
0
(4) R JACK FRICK (i)
(ii)		 217,709
0 		45,908
0 		1,980
0 		92,939
0 		8,148
0 		366,684
0 		0
0
(5) TIMOTHY MYERS (i)
(ii)		 146,863
0 		9,449
0 		287
0 		82,810
0 		8,148
0 		247,557
0 		0
0
(6) KATHLEEN VOGELSANG (i)
(ii)		 164,031
0 		16,016
0 		690
0 		27,429
0 		8,147
0 		216,313
0 		0
0
(7) DR H ERIC XU (i)
(ii)		 245,796
0 		20,985
0 		450
0 		40,626
0 		8,147
0 		316,004
0 		0
0
(8) DR JAMES RESAU (i)
(ii)		 186,741
0 		3,712
0 		1,980
0 		31,830
0 		8,147
0 		232,410
0 		0
0
(9) JOHN BENDER (i)
(ii)		 209,861
0 		10,000
0 		13,379
0 		23,455
0 		8,148
0 		264,843
0 		0
0
(10) BRYON CAMPBELL (i)
(ii)		 172,363
0 		6,445
0 		690
0 		27,410
0 		8,147
0 		215,055
0 		0
0
(11) STEVE HEACOCK FORMER (i)
(ii)		 90,579
0 		60,371
0 		464,169
0 		18,751
0 		4,344
0 		638,214
0 		0
0





Schedule J (Form 990) 2010

Schedule J (Form 990) 2010
Page 3
Part III
Supplemental Information
Complete this part to provide the information, explanation, or descriptions required for Part I, lines 1a, 1b, 4c, 5a, 5b, 6a, 6b, 7, and 8. Also complete this part for any additional information.
Identifier Return Reference Explanation
  PART I, LINE 1A VARI ALLOWS FOR FIRST-CLASS OR CHARTER TRAVEL TO OFFICERS AND TRUSTEES. FITNESS CENTER MEMBERSHIP DUES WERE PAID BY VARI FOR STEVE HEACOCK TOTALING $500 FOR CALENDAR YEAR 2010. PART I, LINE 1B: THERE IS NOT A POLICY FOR HOUSING ALLOWANCE OR RESIDENCE FOR PERSONAL USE. THIS IS OFFERED ONLY ON RARE OCCASIONS AND FOR SPECIAL CIRCUMSTANCES. HUMAN RESOURCES MANAGES THIS ON A CASE BY CASE BASIS.
  PART I, LINE 1B A WRITTEN POLICY IS IN PLACE FOR FIRST CLASS/ CHARTER TRAVEL AND HEALTH/ SOCIAL CLUB DUES/ FEES.
SUPPLEMENTAL INFORMATION PART III PART I, LINE 4A: SEVERANCE PAID TO STEVE HEACOCK TOTALED $0 IN FISCAL YEAR 2011, $448,871 IN CALENDAR YEAR 2010 PART I, LINE 4B: STEVE HEACOCK $0 FOR FISCAL YEAR 2011 AND $3,808 CALENDAR YEAR 2010 GEORGE VANDE WOUDE $16,500 FISCAL YEAR 2011 AND CALENDAR YEAR 2010
Schedule J (Form 990) 2010

Additional Data


Software ID:  
Software Version:  
Schedule K
(Form 990)
Department of the Treasury
Internal Revenue Service
Supplemental Information on Tax Exempt Bonds
SchKMediumBullet Complete if the organization answered "Yes" to Form 990, Part IV, line 24a. Provide descriptions,
explanations, and any additional information in Schedule O (Form 990).
SchKMediumBullet Attach to Form 990. SchKMediumBullet See separate instructions.
OMB No. 1545-0047
2010
Open to Public
Inspection
Name of the organization
VAN ANDEL RESEARCH INSTITUTE
 
Employer identification number
52-2000823
Part I
Bond Issues
(a) Issuer Name (b) Issuer EIN (c) CUSIP # (d) Date Issued (e) Issue Price (f) Description of Purpose (g) Defeased (h) On
Behalf of
Issuer 		(i) Pool
financing
Yes No Yes No Yes No
A MICHIGAN STRATEGIC FUND LIMITED OBLIGATION REVENUE
  		52-1417332 594698EG3 04-10-2008 220,000,000 BUILD, EQUIP & FURNISH PHASE II RESEARCH FACILITY, & REFUND $50M PRIOR LTD   X   X   X
Part II
Proceeds
A B C D
1 Amount of bonds retired. . . . .        
2 Amount of bonds defeased . . . .        
3 Total proceeds of issue . . . . 223,154,512      
4 Gross proceeds in reserve funds . .        
5 Capitalized interest from proceeds.        
6 Proceeds in refunding escrow. . . . .        
7 Issuance costs from proceeds . . .        
8 Credit enhancement from proceeds.        
9 Working capital expenditures from proceeds . .        
10 Capital expenditures from proceeds . . 113,036,720      
11 Other spent proceeds . . 110,117,792      
12 Other unspent proceeds. . .        
13 Year of substantial completion . . . 2009
Yes No Yes No Yes No Yes No
14 Were the bonds issued as part of a current refunding issue? X              
15 Were the bonds issued as part of an advance refunding issue?   X            
16 Has the final allocation of proceeds been made? . . X              
17 Does the organization maintain adequate books and records to support the final allocation of proceeds? . X              
Part III
Private Business Use
A B C D
Yes No Yes No Yes No Yes No
1 Was the organization a partner in a partnership, or a member of an LLC, which owned property financed by tax-exempt bonds? . . .   X            
2 Are there any lease arrangements that may result in private business use of bond-financed property? . . . . . X              
For Privacy Act and Paperwork Reduction Act Notice, see the Instructions for Form 990.
Cat. No. 50193E
Schedule K (Form 990) 2010
Schedule K (Form 990) 2010
Page 2
Part III
Private Business Use (Continued)
A B C D
Yes No Yes No Yes No Yes No
3a Are there any management or service contracts that may result in private business use? X              
b Are there any research agreements that may result in private business use of bond-financed property? . . X              
c Does the organization routinely engage bond counsel or other outside counsel to review any management or service contracts or research agreements relating to the financed property? . X              
4 Enter the percentage of financed property used in a private business use by entities other than a section 501(c)(3) organization or a state or local government . . . . . . . . . . . . . SchKMediumBullet        
5 Enter the percentage of financed property used in a private business use as a result of unrelated trade or business activity carried on by your organization, another section 501(c)(3) organization, or a state or local government . SchKMediumBullet 0.860 %      
6 Total of lines 4 and 5 . . .. . . . . . 0.860 %      
7 Has the organization adopted management practices and procedures to ensure the post-issuance compliance of its tax-exempt bond liabilities? X              
Part IV
Arbitrage
A B C D
Yes No Yes No Yes No Yes No
1 Has a Form 8038-T, Arbitrage Rebate, Yield Reduction and Penalty in Lieu of Arbitrage Rebate, been filed with respect to the bond issue? . . . X              
2 Is the bond issue a variable rate issue? X              
3a Has the organization or the governmental issuer entered into a hedge with respect to the bond issue?   X            
b Name of provider .  
  		 
  		 
  		 
 
c Term of hedge . .        
d Was the hedge superintegrated? .                
e Was a hedge terminated? .                
4a Were gross proceeds invested in a GIC? .   X            
b Name of provider .  
  		 
  		 
  		 
 
c Term of GIC . .        
d Was the regulatory safe harbor for establishing the fair market value of the GIC satisfied? .                
5 Were any gross proceeds invested beyond an available temporary period? .   X            
6 Did the bond issue qualify for an exception to rebate? . . .   X            
Schedule K (Form 990) 2010

Schedule K (Form 990) 2010
Page 3
Part V
Supplemental Information
Complete this part to provide additional information for responses to questions on Schedule K (see instructions).
Identifier Return Reference Explanation
Schedule K (Form 990) 2010

Additional Data


Software ID:  
Software Version:  

SCHEDULE O
(Form 990 or 990-EZ)

Department of the Treasury
Internal Revenue Service
Supplemental Information to Form 990 or 990-EZ

Complete to provide information for responses to specific questions on
Form 990 or to provide any additional information.
MediumBullet Attach to Form 990 or 990-EZ.
OMB No. 1545-0047
2010
Open to Public
Inspection
Name of the organization
VAN ANDEL RESEARCH INSTITUTE
 
Employer identification number

52-2000823
Identifier Return Reference Explanation
FORM 990, PART VI, SECTION A, LINE 2   VARI AND VAEI SHARE COMMON MANAGEMENT. AS OFFICERS OF VARI, DAVID VAN ANDEL, R. JACK FRICK, TIMOTHY MYERS AND DAVID WHITESCARVER INTERACT AND WORK TOGETHER WITH STEVE TRIEZENBERG, A KEY EMPLOYEE OF VAEI.
FORM 990, PART VI, SECTION A, LINE 3   JERRY CALLAHAN, AN INDEPENDENT CONTRACTOR, SERVES AS THE VICE PRESIDENT OF BUSINESS DEVELOPMENT, TECHNOLOGY TRANSFER, AND OFFICE OF GRANTS AND CONTRACTS.
FORM 990, PART VI, SECTION A, LINE 7A   THE TRUSTEES OF VAN ANDEL INSTITUTE HAVE THE AUTHORITY TO ELECT ONE OR MORE MEMBERS OF VARI'S GOVERNING BODY.
FORM 990, PART VI, SECTION B, LINE 11   FOLLOWING COMPLETION OF THE FINANCIAL AUDIT, THE FORM 990 IS PREPARED AND REVIEWED BY MANAGEMENT. IT IS THEN CIRCULATED TO THE FULL BOARD FOR REVIEW AND FINAL APPROVAL PRIOR TO FILING WITH THE IRS.
  FORM 990, PART VI, SECTION B, LINE 12 VARI HAS A WRITTEN CONFLICT OF INTEREST POLICY FOR WHICH THE ORGANIZATION ENFORCES A PROCESS TO IDENTIFY, EVALUATE, AND CORRECT OR REMOVE POTENTIAL CONFLICTS OF INTEREST. THE VAN ANDEL INSTITUTE ADMINISTERS THE CONFLICT OF INTEREST (COI) POLICY THROUGH TWO COMMITTEES: THE INDIVIDUAL COI COMMITTEE AND THE INSTITUTIONAL COI COMMITTEE. THE COI POLICY SERVES AS GUIDE FOR ALL STAFF MEMBERS OF THE ORGANIZATION. THE POLICY IS INTENDED TO 1) PROVIDE STAFF WITH A USEFUL RESOURCE WHEN DEVELOPING ACTIVITIES WITH OUTSIDE INDUSTRY AND 2) PROVIDE ASSURANCE TO STAFF THAT THERE IS A COMMITTEE TO REVIEW AND RESOLVE POTENTIAL CONFLICTS OF INTEREST IF / WHEN THEY ARISE. THE INDIVIDUAL COI COMMITTEE, CHAIRED BY THE DIRECTOR OF COMPLIANCE, GENERATES AN ANNUAL DISCLOSURE QUESTIONNAIRE DISTRIBUTED TO ALL STAFF TO ENFORCE THE POLICY. THE CONFLICTS COMMITTEE IS RESPONSIBLE FOR MAKING RECOMMENDATIONS TO THE DIRECTOR. RESOLUTIONS ARE IMPLEMENTED WITH APPROVAL OF THE COMMITTEE AND IN DISCUSSION WITH THE VAI CHAIRMAN. THE COI POLICY ALSO SERVES AS A GUIDE FOR ALL MEMBERS OF THE BOARD OF TRUSTEES AND SENIOR EXECUTIVES. THE INSTITUTIONAL COI COMMITTEE REQUIRES TRUSTEES TO COMPLETE AN ANNUAL DISCLOSURE STATEMENT. THIS STATEMENT AFFIRMS THEIR UNDERSTANDING OF THE POLICY, REQUIRES THEIR ACKNOWLEDGEMENT OF THE ORGANIZATION'S NONPROFIT STATUS, AND REQUESTS DISCLOSURE IF / WHEN POTENTIAL CONFLICTS ARISE. IN THE EVENT A POTENTIAL CONFLICT ARISES AT THE BOARD OR SENIOR OFFICER LEVEL, THE OFFICE OF THE GENERAL COUNSEL REVIEWS AND MEETS WITH THE BOARD OF TRUSTEES TO RESOLVE POTENTIAL CONFLICTS.
  FORM 990, PART VI, SECTION B, LINE 15 COMPENSATION FOR THE CEO, EXECUTIVE MANAGEMENT OFFICIALS, EXECUTIVE DIRECTOR, OFFICERS, AND KEY EMPLOYEES IS REVIEWED AND APPROVED ANNUALLY BY THE VAN ANDEL INSTITUTE'S INDEPENDENT COMPENSATION COMMITTEE. RECORDS AND DOCUMENTATION, INCLUDING COMPARABILITY DATA, ARE KEPT AND SUPPORT DECISIONS MADE ON BEHALF OF THESE ARRANGEMENTS AND ARE CONTEMPORANEOUSLY DOCUMENTED.
  FORM 990, PART VI, SECTION C, LINE 19 THESE DOCUMENTS ARE AVAILABLE TO THE PUBLIC UPON REQUEST.
  FORM 990, PART VII, SECTION B COMPENSATION FOR HUNT - OWEN AMES & KIMBALL EXCLUDES ESTIMATED MATERIALS AND INCLUDES ESTIMATED LABOR ON HUNT MANAGED SUB-CONTRACTORS.
  FORM 990, PART VII, SECTION B JEFFREY BATTERSHALL IS LISTED AS SECRETARY ON PAGE 7. HE SERVED ON AN INTERIM BASIS AND WAS CONTRACTED FOR THIS PURPOSE THROUGH THE LAW FIRM WARNER, NORCROSS, & JUDD THROUGH OCTOBER 2011. ALL PAYMENTS FOR HIS SERVICES WERE PAID DIRECTLY TO WARNER, NORCROSS, & JUDD.
  FORM 990, PART VII, PAGE 7 DAVID VAN ANDEL, R. JACK FRICK, TIMOTHY MYERS, JEFFREY BATTERSHALL, AND DAVID WHITESCARVER ALSO PERFORMED WORK FOR VAN ANDEL INSTITUTE, VAN ANDEL EDUCATION INSTITUTE, AND VAN ANDEL INSTITUTE GRADUATE SCHOOL (RELATED ENTITIES).
CHANGES IN NET ASSETS OR FUND BALANCES: FORM 990, PART XI, LINE 5: NET UNREALIZED LOSSES ON INVESTMENTS: -251,644. LOSS ON BOND INTEREST SWAP -26,887,187. TOTAL TO FORM 990, PART XI, LINE 5: -27,138,831.
  FORM 990, PART XII, LINE 2C THE PROCESS FOR SELECTING THE AUDITOR FOR VAN ANDEL RESEARCH INSTITUTE'S FINANCIAL STATEMENTS DID NOT CHANGE DURING 2011.
VARI'S THREE LARGEST PROGRAM SERVICES BY EXPENSES FORM 990, PART III, LINES 4A-4C LINE 4A - PROGRAM SERVICE ACTIVITY #1 THE LABORATORY OF STRUCTURAL SCIENCES IS FOCUSED ON STUDYING THE STRUCTURES AND FUNCTIONS OF PROTEIN/ LIGAND COMPLEXES THAT PLAY KEY ROLES IN MAJOR HORMONE SIGNALING PATHWAYS. THE LABORATORY ALSO WORKS ON EXPLORING THE STRUCTURAL INFORMATION TO DEVELOP THERAPEUTIC AGENTS FOR TREATING HUMAN DISEASE, INCLUDING CANCER AND DIABETES. LAB STUDIES USE MULTIDISCIPLINARY APPROACHES, INCLUDING MOLECULAR AND CELLULAR BIOLOGY, BIOCHEMISTRY, ANIMAL PHYSIOLOGY, X-RAY CRYSTALLOGRAPHY, AND PLANT HORMONE ABSCISIC ACID (ABA) RECEPTORS. RESEARCH IN THIS GROUP CURRENTLY FOCUSES ON THREE AREAS: NUCLEAR HORMONE RECEPTORS, THE MET TYROSINE KINASE RECEPTOR, AND G PROTEIN-COUPLED RECEPTORS. THESE PROTEINS, BEYOND THEIR FUNDAMENTAL ROLES IN BIOLOGY, ARE IMPORTANT DRUG TARGETS. RECENT DISCOVERIES INCLUDE: THE CRYSTAL STRUCTURES OF EACH PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) LIGAND-BINDING DOMAIN (LBD) BOUND TO MANY DIVERSE LIGANDS IN ORDER TO UNDERSTAND THE MOLECULAR BASIS OF LIGAND-MEDIATED SIGNALING BY PPAR'S; THE CRYSTAL STRUCTURES OF THE RECEPTORS BOUND TO COACTIVATORS OR CO-REPRESSORS, WHICH PROVIDES A FRAMEWORK FOR UNDERSTANDING THE MECHANISMS OF PPAR AGONISTS AND ANTAGONIST AND THE RECRUITMENT OF COACTIVATORS AND CO-REPRESSORS; ANDROGEN RECEPTOR (AR) MUTATION IN PROSTATE CANCERS OFTEN RESULTS IN ENHANCED BINDING TO A PARTICULAR COACTIVATOR, SRC-3 (WHICH IS ALSO CALLED "AMPLIFIED IN BREAST CANCER1", OR AIB1); AND RETINOIC ACID IS A LOW-AFFINITY LIGAND FOR COUP-TF, WHICH IS ONE OF THE MOST CONSERVED NUCLEAR RECEPTORS AND HAS ESSENTIAL ROLES IN ANGIOGENESIS, HEART DEVELOPMENT, CNS ACTIVITY, AND METABOLIC HOMEOSTASIS. LINE 4B - PROGRAM SERVICE ACTIVITY #2 SINCE DISCOVERING THE C-MET RECEPTOR AND ITS LIGAND HEPATOCYTE GROWTH FACTOR (HGF/SF) IN THE MID-1980S, THE LABORATORY OF MOLECULAR ONCOLOGY HAS FOCUSED ON INVESTIGATING THE PARAMOUNT ROLE THESE PROTEINS PLAY IN MALIGNANT PROGRESSION AND METASTASIS. MET IS OVEREXPRESSED IN MANY TYPES OF HUMAN CANCER, AND ITS EXPRESSION CORRELATES WITH AN AGGRESSIVE DISEASE AND POOR PROGNOSIS (HTTP://WWW.VAI.ORG/MET/). THE MAJOR ADVANCES MADE IN THE PAST DECADE IN UNDERSTANDING HGF/SF-MET CELLULAR SIGNALING HAVE PROVIDED POWERFUL RATIONALE FOR THE DEVELOPMENT OF INHIBITORS TARGETING IT. SEVERAL OF THESE INNOVATIVE INHIBITORS ARE CURRENTLY BEING EVALUATED IN CLINICAL TRIALS (HTTP://WWW.VAI.ORG/METCLINICALTRIALS/). THE ABERRANT EXPRESSION OF MET IN MANY HUMAN TUMORS ALSO NECESSITATED THE DEVELOPMENT OF COMPANION DIAGNOSTICS TO IDENTIFY THOSE PATIENTS WHO COULD BENEFIT FROM MET TARGETED THERAPIES. IN COLLABORATION WITH DR. BRIAN CAO, WE HAVE DEVELOPED A MONOCLONAL ANTIBODY (DESIGNATED MET4), WHICH WE BELIEVE WILL PROVE VALUABLE AS A DIAGNOSTIC REAGENT AS WELL AS AN ESSENTIAL RESEARCH TOOL. AS PART OF THE ONGOING EFFORT TO FURTHER ENHANCE OUR UNDERSTATING OF THE HGF/SF-MET SIGNALING SYSTEM, OUR LAB CURRENTLY FOCUSES ON THE PROJECTS DESCRIBED BELOW: -CONTINUING TO DEVELOP AND CHARACTERIZE NOVEL RESEARCH MODELS FOR A VARIETY OF HUMAN CANCERS (LIVER, BRAIN, BREAST, LUNG AND OTHERS) AND USING THEM IN PRE-CLINICAL EVALUATION OF NEW C-MET INHIBITORS AS WELL AS OTHER THERAPEUTIC STRATEGIES -EVALUATING HGF AUTOCRINE AS A THERAPEUTIC MARKER PREDICTING SENSITIVITY TO C-MET INHIBITION USING VARIOUS GLIOBLASTOMA AND HEPATOCELLULAR CARCINOMA MODELS -INVESTIGATING THE UNIQUE ROLES THAT C-MET AND ERBB2 PLAY IN THE PROGRESSION AND METASTASIS OF AGGRESSIVE BREAST CANCERS -STUDYING THE MECHANISMS RESPONSIBLE FOR PHENOTYPIC SWITCHING (E-MT/M-ET) AND EVALUATING THE ROLE OF CHROMOSOME INSTABILITY IN TUMOR PROGRESSION -DETERMINING THE TUMOR SUPPRESSOR ROLE OF MIG-6 AS WELL AS INVESTIGATING THE MOLECULAR MECHANISM UNDERLYING ITS FUNCTION IN BOTH CANCER AND OSTEOARTHRITIS LINE 4C - PROGRAM SERVICE ACTIVITY #3 THE LABORATORY OF TRANSLATIONAL MEDICINE (LTM) IS FOCUSED ON TWO CRITICAL AREAS OF CANCER RESEARCH. AT THE BASIC SCIENCE LEVEL, THE LAB IS UTILIZING A RANGE OF MOLECULAR AND COMPUTATIONAL TECHNOLOGIES TO STUDY HOW TUMORS SPREAD TO DISTANT PARTS OF THE BODY FROM ITS ORIGINAL LOCATION - THIS PROCESS, KNOWN AS METASTASIS, IS ACCOUNTABLE FOR >90% OF CANCER RELATED DEATHS, AND THE IDENTIFICATION OF NEW DIAGNOSTIC AND TREATMENT STRATEGIES TARGETING THIS LETHAL PHENOTYPE OF CANCER ARE OF UTTERMOST IMPORTANCE. IN THE AREA OF APPLIED RESEARCH, THE LTM IS FOCUSED ON DEVELOPING AND IMPLEMENTING STRATEGIES TO "PERSONALIZE" THE TREATMENT OF A RANGE OF AGGRESSIVE CANCERS WITH MOLECULARLY-GUIDED THERAPIES. THE LTM CONTINUES TO BE AT THE FOREFRONT OF DESIGNING AND IMPLEMENTING APPROACHES IN WHICH THE TREATMENT OF AN INDIVIDUAL PATIENT'S CANCER IS BASED UPON THE MOLECULAR ANALYSIS OF THAT PATIENT AND THEIR SPECIFIC DISEASE. TO FACILITATE THIS, THE LAB DESIGNED AND DEVELOPED AN INTEGRATED, BIOMEDICAL INFORMATICS SYSTEM FOR DATA MANAGEMENT, ANALYSIS, AND REPORTING (KNOWN AS XENOBASE BIOINTEGRATION SUITE (XB-BIS)). IN ADDITION, THE LAB HAS BEEN HEAVILY INVOLVED IN COMMUNITY FOUNDING PARTNERSHIPS THAT HAVE INCLUDED THE FORMATION OF A BIOMARKER-DRIVEN CLINICAL TRIALS CONSORTIUM (CLINXUS), A HIGH COMPLEXITY CLIA CERTIFIED LABORATORY (THE CENTER FOR MOLECULAR MEDICINE), AND A PERSONALIZED MEDICINE INFORMATION SERVICE COMPANY (INTERVENTION INSIGHTS) WHICH COLLECTIVELY, PERMIT THE APPLICATION OF PERSONALIZED THERAPY FOR LATE STAGE CANCER PATIENTS. RECENT ACCOMPLISHMENTS INCLUDE THE DEVELOPMENT AND COMMERCIALIZATION OF AN INTEGRATED INFORMATICS SOLUTION (XB-BIS), WHICH ENABLES EFFICIENT EXCHANGE OF INFORMATION BETWEEN THE BASIC RESEARCH LABORATORY AND THE CLINIC FOR EFFECTIVE TRANSLATIONAL RESEARCH. XB-BIS HAS BEEN LICENSED TO TRANSMED SYSTEMS WHICH IS NOW SUPPORTING ITS ADOPTION ACROSS MULTIPLE GROUPS ENGAGED IN TRANSLATIONAL RESEARCH BOTH WITHIN THE UNITED STATES AND BEYOND. IN PART THROUGH THE USE OF XB-BIS, THE LAB RECENTLY COMPLETED A FEASIBILITY STUDY OF 50 LATE-STAGE PEDIATRIC AND ADULT CANCER PATIENTS IN WHICH TUMOR-DERIVED GENE EXPRESSION PROFILES WERE ANALYZED TO IDENTIFY POTENTIAL DRUGS TO TARGET PERTURBED MOLECULAR COMPONENTS OF EACH PATIENT'S SPECIFIC TUMOR. ANECDOTAL SIGNS OF SUCCESS IN A HANDFUL OF PATIENTS PROVIDED THE IMPETUS TO LAUNCH A SERIES OF FOLLOW-UP STUDIES WITHIN FOCUSED PATIENT POPULATIONS, AND ALSO LED TO THE FORMATION OF INTERVENTION INSIGHTS, A PERSONALIZED MEDICINE INFORMATION SERVICE THAT SUPPORTS COMMUNITY AND ACADEMIC ONCOLOGISTS ACROSS THE UNITED STATES. AT VARI, THE LTM CONTINUES TO ADVANCE THE MOLECULAR AND COMPUTATIONAL TECHNOLOGIES AND IS CURRENTLY INVESTIGATING THE POTENTIAL USE OF NEXT GENERATION SEQUENCING TECHNOLOGIES IN TARGETED TRIALS OF NEUROBLASTOMA (SPONSORED BY THE NEUROBLASTOMA AND MEDULLOBLASTOMA TRANSLATIONAL RESEARCH CONSORTIUM (NMTRC) AND IN PARTNERSHIP WITH DELL AND INTERVENTION INSIGHTS), METASTATIC MELANOMA (SPONSORED BY A RECENT STAND UP 2 CANCER GRANT), TRIPLE NEGATIVE BREAST CANCER (SPONSORED BY A KOMEN PROMISE GRANT), AND GLIOBLASTOMA (SPONSORED BY HENRY FORD HOSPITAL AND A RECENT NIH GRANT).
  FORM 990, PART III, LINE 4D ALL OTHER PROGRAM SERVICE ACTIVITIES IN 2011, VARI RESEARCHERS FOUND WAYS TO POTENTIALLY DIAGNOSE AND FIGHT SEVERAL DIFFERENT TYPES OF CANCER. IN 2011, VARI ALSO ANNOUNCED A PATENT WITH GENTEL BIOSCIENCES, A LEADER IN PROTEOMICS TOOLS, FOR A NEW APPROACH TO IDENTIFY BIOLOGICAL MARKERS TO HELP DIAGNOSE DISEASES SUCH AS CANCER. BELOW ARE OTHER EXAMPLES OF SIGNIFICANT RESEARCH FINDINGS: -VARI ANNOUNCED THE CREATION OF THE VARI PEDIATRIC CANCER TRANSLATIONAL RESEARCH PROGRAM, A PROJECT THAT UNITES BASIC RESEARCH AND CLINICAL CARE THROUGH A NATIONWIDE CONSORTIUM OF PARTNERS. -RESEARCHERS DETERMINED HOW THE ANTI-CANCER ANTIBIOTIC GELDANAMYCIN AND ITS DERIVATIVE 17AAG WORK IN MORE DETAIL AND HAVE UNCOVERED A POSSIBLE EXPLANATION FOR SIDE EFFECTS, WHICH COULD INFORM FUTURE DRUG DESIGN. -RESEARCHERS IDENTIFIED MK-STYX AS AN ENZYME THAT HELPS TO REGULATE CELL DEATH, AND FOUND OUT MORE ABOUT SPECIFICALLY HOW MK-STYX WORKS. -RESEARCHERS IDENTIFIED THE GENE POLO-LIKE KINASE 1 (PLK1) AS A NEW POTENTIAL DRUG TARGET TO TREAT CLEAR CELL RENAL CELL CARCINOMA (CCRCC), THE MOST COMMON FORM OF KIDNEY CANCER. THEY ALSO FOUND THAT THE PLK1 INHIBITOR BI 2536, CURRENTLY IN CLINICAL TRIALS FOR THE TREATMENT OF SEVERAL CANCERS, LED TO DRAMATIC REGRESSION OF CCRCC TUMORS. -RESEARCHERS IDENTIFIED AN ENZYME, LRRK2, THAT SEEMS TO COOPERATE WITH MET, AN IMPORTANT GENE IN SEVERAL CANCERS, TO PROMOTE TUMOR CELL GROWTH AND SURVIVAL, SPECIFICALLY IN PAPILLARY RENAL AND THYROID CARCINOMAS. -RESEARCHERS IDENTIFIED SPECIFIC PROTEINS THAT CARRY THE CA 19-9, THE BEST INDICATOR OF PANCREATIC CANCER, ANTIGEN AND MEASURED CA 19-9 LEVELS ON EACH PROTEIN IN AN EFFORT TO ENHANCE BLOOD TESTING. BETTER KNOWLEDGE OF THESE CARRIERS IN VARIOUS DISEASE STATES COULD LEAD TO IMPROVED DIAGNOSTIC TESTS. -RESEARCHERS INVESTIGATED THE ROLE OF THE PROTEIN HEPATOMA-DERIVED GROWTH FACTOR (HDGF) IN BREAST AND PROSTATE CANCERS AND FOUND THAT IT MAY PROMOTE CELL GROWTH IN THESE CANCERS AND COULD BE A THERAPEUTIC TARGET. -RESEARCHERS FOUND THAT IN SK-MEL-28 MELANOMA CELLS, MEK2, AND NOT MEK1, IS SUFFICIENT FOR CELL PROLIFERATION, BUT THAT MEK1 CAN COMPENSATE FOR THE LOSS OF MEK2 ACTIVITY. THESE INSIGHTS MAY AID IN THE DESIGN OF MORE EFFECTIVE THERAPIES FOR TREATING MELANOMA AND OTHER MEK-DEPENDENT CANCERS. -IN COLLABORATION WITH RESEARCHERS FROM ANOTHER ORGANIZATION, RESEARCHERS IDENTIFIED A NOVEL MARKER THAT COULD HELP DIAGNOSE TYPE II EATL, WHICH IS THE TYPE MORE COMMON IN ASIA AND NOT ASSOCIATED WITH COELIAC DISEASE. -IN ADDITION TO THOSE LISTED ABOVE, THERE WERE ALSO FINDINGS WITHIN MELANOMA, BRAIN CANCER, HEAD AND NECK CANCER, ALZHEIMER'S DIABETES, AUTOIMMUNE DISEASE, RETINOPATHY, AND HOOKWORM.
  FORM 990, PART X, LINE 33 VARI NET ASSETS SHOULD BE CONSIDERED ON A CONSOLIDATED BASIS WITH VAN ANDEL INSTITUTE (VAI), VAN ANDEL EDUCATION INSTITUTE (VAEI), AND THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (TGEN), RELATED PARTIES. ON A CONSOLIDATED BASIS, NET ASSETS ARE $896,445,000 PER AUDITED FINANCIAL STATEMENTS. THE NEGATIVE NET ASSETS AT VARI ARE DUE TO VAI FUNDING EXPENSES ON A CASH BASIS AND GUARANTEEING VARI'S LONG-TERM DEBT AND UNREALIZED BOND SWAP LOSS.
  FORM 990, PART IX, COLUMN D FUNDRAISING EXPENSES AT VARI WERE INCURRED TO SUPPORT THE MISSION OF THE RESEARCH INSTITUTE THROUGH GRANT SOLICITATION AND EXTRAMURAL PROPOSAL PREPARATION.
  FORM 990, PART VI, LINES 12-14 THE INSTITUTE DOES HAVE A WRITTEN CONFLICT OF INTEREST POLICY, A WRITTEN WHISTLEBLOWER POLICY, AND A WRITTEN DOCUMENT RETENTION POLICY; HOWEVER, IS REQUIRED TO CHECK NO BASED ON THE IRS INSTRUCTIONS AS THESE POLICIES HAVE NOT BEEN OFFICIALLY APPROVED BY OUR BOARD.
For Paperwork Reduction Act Notice, see the Instructions for Form 990 or 990-EZ.
Cat. No. 51056K
Schedule O (Form 990 or 990-EZ) 2010

Additional Data


Software ID:  
Software Version:  
SCHEDULE R
(Form 990)
Department of the Treasury
Internal Revenue Service
Related Organizations and Unrelated Partnerships
MediumBulletComplete if the organization answered "Yes" to Form 990, Part IV, line 33, 34, 35, 36, or 37.
MediumBulletAttach to Form 990. MediumBullet See separate instructions.

OMB No. 1545-0047
2010
Open to Public Inspection
Name of the organization
VAN ANDEL RESEARCH INSTITUTE
 
Employer identification number

52-2000823
Part I
Identification of Disregarded Entities (Complete if the organization answered "Yes" on Form 990, Part IV, line 33.)
(a)
Name, address, and EIN of disregarded entity


(b)
Primary activity


 		(c)
Legal domicile (state
or foreign country)

 		(d)
Total income
(e)
End-of-year assets


 		(f)
Direct controlling
entity







(1) VAI INNOVATIONS LLC
333 BOSTWICK AVENUE NE
GRAND RAPIDS,MI495032518
52-2000823 		LICENSING INTELLECTUAL PROPERTY OF VARI MI -677,549 10,457 VAN ANDEL RESEARCH INSTITUTE
 
(2) VARI INTERNATIONAL
333 BOSTWICK AVENUE NE
GRAND RAPIDS,MI495032518
26-2615936 		BIOMEDICAL RESEARCH MI -27,104 172,207 VAN ANDEL RESEARCH INSTITUTE
 
(3) BOSTWICK EVENT MANAGEMENT
333 BOSTWICK AVENUE NE
GRAND RAPIDS,MI495032518
52-2000823 		EVENT MANAGEMENT MI -74,494 561 VAN ANDEL RESEARCH INSTITUTE
 
(4) VARI-CLINXUS LLC
333 BOSTWICK AVENUE NE
GRAND RAPIDS,MI495032518
27-4015168 		CLINICAL TRIALS MI -47,858 80,282 VAN ANDEL RESEARCH INSTITUTE
 




Part II
Identification of Related Tax-Exempt Organizations (Complete if the organization answered "Yes" on Form 990, Part IV, line 34 because it had one or more related tax-exempt organizations during the tax year.)
(a)
Name, address, and EIN of related organization


(b)
Primary activity


 		(c)
Legal domicile (state
or foreign country)

 		(d)
Exempt Code section
(e)
Public charity status
(if section 501(c)(3))

 		(f)
Direct controlling
entity

 		(g)
Section 512(b)(13) controlled organization
Yes No
(1) VAN ANDEL INSTITUTE

333 BOSTWICK AVENUE NE

GRAND RAPIDS,MI495032518
52-2000820 		SUPPORTING ORGANIZATION FOR VARI AND VAEI MI 501(C)(3) 11C N/A
 
No
(2) VAN ANDEL EDUCATION INSTITUTE

333 BOSTWICK AVENUE NE

GRAND RAPIDS,MI495032518
52-2000824 		OPERATING A SCHOOL MI 501(C)(3) 2 VAN ANDEL INSTITUTE
 
Yes
 
(3) VAN ANDEL INSTITUTE GRADUATE SCHOOL

333 BOSTWICK AVENUE NE

GRAND RAPIDS,ME495032518
20-3340886 		OPERATING A SCHOOL MI 501(C)(3) 2 VAN ANDEL EDUCATION INSTITUTE
 
Yes
 
(4) THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE

445 N 5TH STREET SUITE 600

PHOENIX,AZ85004
75-3065445 		MEDICAL RESEARCH AZ 501(C)(3) 7 VAN ANDEL RESEARCH INSTITUTE
 
Yes
 
(5) TGEN RESEARCH INSTITUTE FOUNDATION

400 E VAN BUREN SUITE 850

PHOENIX,AZ85004
33-1092191 		FUNDRAISING AZ 501(C)(3) 7 THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE
 
Yes
 




For Privacy Act and Paperwork Reduction Act Notice, see the Instructions for Form 990.
Cat. No. 50135Y
Schedule R (Form 990) 2010
Schedule R (Form 990) 2010
Page 2
Part III
Identification of Related Organizations Taxable as a Partnership (Complete if the organization answered "Yes" on Form 990, Part IV, line 34 because it had one or more related organizations treated as a partnership during the tax year.)
(a)
Name, address, and EIN of
related organization



 		(b)
Primary activity




 		(c)
Legal
domicile
(state or foreign
country)


 		(d)
Direct controlling
entity



 		(e)
Predominant income(related, unrelated, excluded from tax under sections 512-514)

(f)
Share of total income




 		(g)
Share of end-of-year
assets



 		(h)
Disproprtionate allocations?




 		(i)
Code V—UBI
amount in box 20 of
Schedule K-1
(Form 1065)
 		(j)
General or
managing
partner?



 		(k)
Percentage
ownership
Yes No Yes No












Part IV
Identification of Related Organizations Taxable as a Corporation or Trust (Complete if the organization answered "Yes" on Form 990, Part IV, line 34 because it had one or more related organizations treated as a corporation or trust during the tax year.)
(a)
Name, address, and EIN of related organization



 		(b)
Primary activity



 		(c)
Legal domicile
(state or
foreign
country)
 		(d)
Direct controlling
entity


 		(e)
Type of entity
(C corp, S corp,
or trust)

 		(f)
Share of total income



 		(g)
Share of
end-of-year
assets

 		(h)
Percentage
ownership
(1) TRANSMED SYSTEMS INC
21170 CANYON OAK WAY
CUPERTINO,CA95014
27-2358859 		TRANSLATIONAL MEDICAL SOFTWARE AND SERVICES CA VAI INNOVATIONS LLC
  		C -697,483 478,524 55.900 %












Schedule R (Form 990) 2010
Schedule R (Form 990) 2010
Page 3
Part V
Transactions With Related Organizations (Complete if the organization answered "Yes" on Form 990, Part IV, line 34, 35, 35A, or 36.)
Note. Complete line 1 if any entity is listed in Parts II, III or IV.
Yes
No
1 During the tax year, did the orgranization engage in any of the following transactions with one or more related organizations listed in Parts II-IV?
a Receipt of (i) interest (ii) annuities (iii) royalties (iv) rent from a controlled entity . . . . . . . . . . . . . . . . . . . . . . .
1a
Yes
 
b Gift, grant, or capital contribution to other organization(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1b
Yes
 
c Gift, grant, or capital contribution from other organization(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1c
Yes
 
d Loans or loan guarantees to or for other organization(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1d
 
No
e Loans or loan guarantees by other organization(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1e
Yes
 
f Sale of assets to other organization(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1f
Yes
 
g Purchase of assets from other organization(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1g
 
No
h Exchange of assets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1h
 
No
i Lease of facilities, equipment, or other assets to other organization(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1i
 
No
j Lease of facilities, equipment, or other assets from other organization(s) . . . . . . . . . . . . . . . . . . . . . . . . . . .
1j
 
No
k Performance of services or membership or fundraising solicitations for other organization(s) . . . . . . . . . . . . . . . . . . . . . .
1k
Yes
 
l Performance of services or membership or fundraising solicitations by other organization(s) . . . . . . . . . . . . . . . . . . . . . .
1l
 
No
m Sharing of facilities, equipment, mailing lists, or other assets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1m
Yes
 
n Sharing of paid employees . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1n
Yes
 
o Reimbursement paid to other organization for expenses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1o
Yes
 
p Reimbursement paid by other organization for expenses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1p
Yes
 
q Other transfer of cash or property to other organization(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1q
Yes
 
r Other transfer of cash or property from other organization(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1r
 
No
2
If the answer to any of the above is "Yes," see the instructions for information on who must complete this line, including covered relationships and transaction thresholds.
(a)
Name of other organization 		(b)
Transaction
type(a-r) 		(c)
Amount involved 		(d)
Method of determining amount involved
(1) VAN ANDEL INSTITUTE

 C 47,313,999 ACTUAL AMOUNT PAID
(2) VAN ANDEL INSTITUTE

 E 48,620,000 TOTAL RECORDED
(3) VAN ANDEL INSTITUTE

 M 297,622 ALLOCATION BASED ON SQ. FOOTAGE
(4) VAN ANDEL INSTITUTE

 O 189,048 ACTUAL AMOUNT PAID
(5) VAN ANDEL EDUCATION INSTITUTE

 O 61,273 ACTUAL AMOUNT PAID
(6) VAN ANDEL EDUCATION INSTITUTE

 P 296,896 ACTUAL AMOUNT RECEIVED
(7) VAN ANDEL EDUCATION INSTITUTE

 N 63,099 APPORTIONED SALARY AND BENEFITS
(8) VAN ANDEL INSTITUTE GRADUATE SCHOOL

 M 178,573 ALLOCATION BASED ON SQ. FOOTAGE
(9) VAN ANDEL INSTITUTE GRADUATE SCHOOL

 P 139,244 ACTUAL AMOUNT RECEIVED
(10) THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE

 Q 10,928,790 ACTUAL AMOUNT PAID
(11) THE TRANSLATIONAL GENOMIC RESEARCH INSTITUTE

 N 465,845 NET AMOUNT INVOICED
(12) THE TRANSLATIONAL GENOMIC RESEARCH INSTITUTE

 C 1,578,641 ACTUAL GRANT TOTAL
(13) THE TRANSLATIONAL GENOMIC RESEARCH INSTITUTE

 K 452,155 ACTUAL AMOUNT PAID
(14) THE TRANSLATIONAL GENOMIC RESEARCH INSTITUTE

 B 36,865 ACCRUED PER CONTRACT
(15) THE TRANSLATIONAL GENOMIC RESEARCH INSTITUTE

 O 17,472 ACTUAL AMOUNT PAID
(16) THE TRANSLATIONAL GENOMIC RESEARCH INSTITUTE

 F 9,000 ACTUAL AMOUNT RECEIVED
(17) TRANSMED SYSTEMS INC

 A 374,185 ACCRUED PER CONTRACT
(18) TRANSMED SYSTEMS INC

 B 500,000 ACTUAL AMOUNT PAID
Schedule R (Form 990) 2010
Schedule R (Form 990) 2010
Page 4
Part VI
Unrelated Organizations Taxable as a Partnership (Complete if the organization answered "Yes" on Form 990, Part IV, line 37.)
Provide the following information for each entity taxed as a partnership through which the organization conducted more than five percent of its activities (measured by total assets or gross revenue) that was not a related organization. See instructions regarding exclusion for certain investment partnerships.
(a)
Name, address, and EIN of entity 		(b)
Primary activity 		(c)
Legal domicile
(state or foreign
country) 		(d)
Are all
partners
section
501(c)(3)
organizations? 		(e)
Share of
end-of-year
assets 		(f)
Disproprtionate allocations? 		(g)
Code V—UBI
amount in box
20 of Schedule K-1
(Form 1065) 		(h)
General or
managing
partner?
Yes No Yes No Yes No






























Schedule R (Form 990) 2010
Schedule R (Form 990) 2010
Page 5
Part VII
Supplemental Information
Complete this part to provide additional information for responses to questions on Schedule R (see instructions).
Identifier Return Reference Explanation
Additional Data


Software ID:  
Software Version: