Department of the Treasury Internal Revenue Service
Public Charity Status and Public Support
Complete if the organization is a section 501(c)(3) organization or a section
4947(a)(1) nonexempt charitable trust.
Attach to Form 990 or Form 990-EZ. See separate instructions.
OMB No. 1545-0047
2010
Open to Public Inspection
Name of the organization
CHILDREN'S RESEARCH INSTITUTE
Employer identification number
52-1654453
Part I
Reason for Public Charity Status
(All organizations must complete this part.) See instructions
The organization is not a private foundation because it is: (For lines 1 through 11, check only one box.)
1
2
3
4
5
section 170(b)(1)(A)(iv). (Complete Part II.)
6
7
8
9
receipts from activities related to its exempt functions—subject to certain exceptions, and (2) no more than 331/3% of
its support from gross investment income and unrelated business taxable income (less section 511 tax) from businesses
acquired by the organization after June 30, 1975. See section 509(a)(2). (Complete Part III.)
10
11
e
By checking this box, I certify that the organization is not controlled directly or indirectly by one or more disqualified persons other than foundation managers and other than one or more publicly supported organizations described in section 509(a)(1) or section 509(a)(2).
f
If the organization received a written determination from the IRS that it is a Type I, Type II or Type III supporting organization, check this box
..................................................
g
Since August 17, 2006, has the organization accepted any gift or contribution from any of the following persons?
(i) a person who directly or indirectly controls, either alone or together with persons described in (ii)
Yes
No
and (iii) below, the governing body of the the supported organization?
................
11g(i)
(ii)
a family member of a person described in (i) above?
......................
11g(ii)
(iii)
a 35% controlled entity of a person described in (i) or (ii) above?
................
11g(iii)
h
Provide the following information about the supported organization(s).
(i) Name of supported organization
(ii) EIN
(iii) Type of organization (described on lines 1- 9 above or IRC section (see instructions))
(iv) Is the organization in col. (i) listed in your governing document?
(v) Did you notify the organization in col. (i) of your support?
(vi) Is the organization in col. (i) organized in the U.S.?
(vii) Amount of support?
Yes
No
Yes
No
Yes
No
Total
For Paperwork Reduction Act Notice, see the Instructions for Form 990.
Cat. No. 11285F
Schedule A (Form 990 or 990-EZ) 2010
Schedule A (Form 990 or 990-EZ) 2010
Page 2
Part II
Support Schedule for Organizations Described in IRC 170(b)(1)(A)(iv) and 170(b)(1)(A)(vi) (Complete only if you checked the box on line 5, 7, or 8 of Part I or if the
organization failed to qualify under Part III. If the organization fails to
qualify under the tests listed below, please complete Part III.)
Section A. Public Support
Calendar year(or fiscal year beginning in)
(a) 2006
(b) 2007
(c) 2008
(d) 2009
(e) 2010
(f) Total
1
Gifts, grants, contributions, and membership fees received. (Do not include any "unusual grants.") ....
2
Tax revenues levied for the organization's benefit and either paid to or expended on its behalf.......
3
The value of services or facilities furnished by a governmental unit to the organization without charge..
4
Total. Add lines 1 through 3..
5
The portion of total contributions by each person (other than a governmental unit or publicly supported organization) included
on line 1 that exceeds 2% of the amount shown on line 11, column (f)..
6
Public Support. Subtract line 5 from line 4.
Section B. Total Support
Calendar year(or fiscal year beginning in)
(a) 2006
(b) 2007
(c) 2008
(d) 2009
(e) 2010
(f) Total
7
Amounts from line 4..
8
Gross income from interest, dividends, payments received on securities loans, rents, royalties and income from similar sources..
9
Net income from unrelated business activities, whether or not the business is regularly carried on..
10
Other income. (Explain in Part IV.) Do not include gain or loss from the sale of capital assets..
11
Total support (Add lines 7 through 10).
12
Gross receipts from related activities, etc. (See instructions.)
..................
12
13
First Five Years
If the Form 990 is for the organization's first, second, third, fourth, or fifth tax year as a 501(c)(3) organization,
check this box and stop here..........................................
Section C. Computation of Public Support Percentage
14
Public Support Percentage for 2010 (line 6 column (f) divided by line 11 column (f))
.........
14
15
Public Support Percentage for 2009 Schedule A, Part II, line 14
...............
15
16a
33 1/3% support test—2010.
If the organization did not check the box on line 13, and line 14 is 33 1/3% or more, check this box
and stop here. The organization qualifies as a publicly supported organization
......................
b
33 1/3% support test—2009.
If the organization did not check the box on line 13 or 16a, and line 15 is 33 1/3% or more, check this
box and stop here. The organization qualifies as a publicly supported organization
.....................
17a
10%-facts-and-circumstances test—2010.
If the organization did not check a box on line 13, 16a, or 16b and line 14
is 10% or more, and if the organization meets the "facts and circumstances" test, check this box and stop here. Explain
in Part IV how the organization meets the "facts and circumstances" test. The organization qualifies as a publicly supported
organization
..................................................
b
10%-facts-and-circumstances test—2009.
If the organization did not check a box on line 13, 16a, 16b, or 17a and line
15 is 10% or more, and if the organization meets the "facts and circumstances" test, check this box and stop here.
Explain in Part IV how the organization meets the "facts and circumstances" test. The organization qualifies as a publicly supported organization
..............................................
18
Private Foundation
If the organization did not check a box on line 13, 16a, 16b, 17a or 17b, check this box and see
instructions
...................................................
Schedule A (Form 990 or 990-EZ) 2010
Schedule A (Form 990 or 990-EZ) 2010
Page 3
Part III
Support Schedule for Organizations Described in IRC 509(a)(2) (Complete only if you checked the box on line 9 of Part I or if the organization
failed to qualify under Part II. If the organization fails to qualify under
the tests listed below, please complete Part II.)
Section A. Public Support
Calendar year(or fiscal year beginning in)
(a) 2006
(b) 2007
(c) 2008
(d) 2009
(e) 2010
(f) Total
1
Gifts, grants, contributions, and membership fees received. (Do not include any "unusual grants.") .
44,070,029
45,238,170
42,866,571
45,771,511
48,636,497
226,582,778
2
Gross receipts from admissions, merchandise sold or services performed, or facilities furnished in any activity that is related to the organization's tax-exempt purpose......
0
0
0
0
0
0
3
Gross receipts from activities that are not an unrelated trade or business under section 513..
4
Tax revenues levied for the organization's benefit and either paid to or expended on its behalf...
5
The value of services or facilities furnished by a governmental unit to the organization without charge..
6
Total. Add lines 1 through 5.
44,070,029
45,238,170
42,866,571
45,771,511
48,636,497
226,582,778
7a
Amounts included on lines 1, 2, and 3 received from disqualified persons...
b
Amounts included on lines 2 and 3 received from other than disqualified persons that exceed the greater of $5,000 or 1% of the amount on line 13 for the year.
c
Add lines 7a and 7b..
8
Public Support (Subtract line 7c from line 6.)
226,582,778
Section B. Total Support
Calendar year (or fiscal year beginning in)
(a) 2006
(b) 2007
(c) 2008
(d) 2009
(e) 2010
(f) Total
9
Amounts from line 6...
44,070,029
45,238,170
42,866,571
45,771,511
48,636,497
226,582,778
10a
Gross income from interest, dividends, payments received on securities loans, rents, royalties and income from similar sources..
8,877
55,116
53,880
0
0
117,873
b
Unrelated business taxable income (less section 511 taxes) from businesses acquired after June 30, 1975.
c
Add lines 10a and 10b.
8,877
55,116
53,880
0
0
117,873
11
Net income from unrelated business activities not included in line 10b, whether or not the business is regularly carried on.
12
Other income. Do not include gain or loss from the sale of capital assets (Explain in Part IV.)
0
0
0
40,180
0
40,180
13
Total support (Add lines 9, 10c, 11 and 12.).
44,078,906
45,293,286
42,920,451
45,811,691
48,636,497
226,740,831
14
First Five Years
If the Form 990 is for the organization's first, second, third, fourth, or fifth tax year as a 501(c)(3) organization,
check this box and stop here.............................................
Section C. Computation of Public Support Percentage
15
Public Support Percentage for 2010 (line 8 column (f) divided by line 13 column (f))
.........
15
99.930 %
16
Public support percentage from 2009 Schedule A, Part III, line 15
...............
16
99.852 %
Section D. Computation of Investment Income Percentage
17
Investment income percentage for 2010 (line 10c column (f) divided by line 13 column (f))
......
17
0.052 %
18
Investment income percentage from 2009 Schedule A, Part III, line 17
.............
18
0.130 %
19a
33 1/3% support tests—2010.
If the organization did not check the box on line 14, and line 15 is more than 33 1/3% and line 17 is not more than 33 1/3%, check this box and stop here. The organization qualifies as a publicly supported organization
..........
b
33 1/3% support tests—2009.
If the organization did not check a box on line 14 or line 19a, and line 16 is more than 33 1/3% and line 18 is not more than 33 1/3%, check this box and stop here. The organization qualifies as a publicly supported organization
....
20
Private Foundation
If the organization did not check a box on line 14, 19a or 19b, check this box and see instructions
.....
Schedule A (Form 990 or 990-EZ) 2010
Schedule A (Form 990 or 990-EZ) 2010
Page 4
Part IV
Supplemental Information.
Supplemental Information. Complete this part to provide the explanation required by Part II, line 10; Part II, line 17a or 17b; or Part III, line 12. Also complete this part for any additional information. (See instructions).
Facts And Circumstances Test
Explanation
Schedule A (Form 990 or 990-EZ) 2010
Additional Data
Software ID:
Software Version:
-
TIN:
SCHEDULE O (Form 990 or 990-EZ)
Department of the Treasury Internal Revenue Service
Supplemental Information to Form 990 or 990-EZ
Complete to provide information for responses to specific questions on
Form 990 or to provide any additional information.
Attach to Form 990 or 990-EZ.
OMB No. 1545-0047
2010
Open to Public Inspection
Name of the organization
CHILDREN'S RESEARCH INSTITUTE
Employer identification number
52-1654453
Identifier
Return Reference
Explanation
PART III, LINE 4D, OTHER CENTERS:
THE CENTER FOR CANCER & IMMUNOLOGY RESEARCH WAS REORGANIZED TO INTEGRATE THE CLINICAL AND RESEARCH ENTERPRISES IN ONCOLOGY, INFECTIOUS DISEASES, AND HEMATOLOGY, IN ORDER TO PROMOTE AND FACILITATE THE CONDUCT OF TRANSLATIONAL RESEARCH. THIS REORGANIZATION RESULTED IN THE ESTABLISHMENT OF 4 SECTIONS: 1. CHILDHOOD CANCER 2. INFECTIOUS DISEASES 3. CANCER IMMUNOLOGY 4. HEMATOLOGY & TRANSFUSION MEDICINE IN THE FUTURE SECTIONS MAY BE ADDED (RHEUMATOLOGY, ALLERGY) OR COMBINED (CHILDHOOD CANCER AND CANCER IMMUNOLOGY), BUT AT THIS POINT IN TIME, THE CREATION OF THESE SECTIONS PROVIDES INDIVIDUAL INVESTIGATORS TO SEEK FOR COMMON RESEARCH THEMES AS WELL AS BETTER IDENTIFY THEIR CLINICAL COUNTERPARTS. ALSO, THE NEW STRUCTURE HAS ALLOWED THE CCRI LEADERSHIP TO BETTER DEVELOP A STRATEGIC GOAL FOR THE FUTURE, INCLUDING STRATEGIC EXPANSION OF RESEARCH PROGRAMS RATHER THAN OPPORTUNISTIC RECRUITMENTS. WHILE THE BREADTH AND DEPTH OF THE CCRI AND CENTER FOR CANCER AND BLOOD DISORDERS ALLOW FOR THE ESTABLISHMENT OF MULTIPLE INSTITUTES (SICKLE CELL DISEASE, TRANSFUSION MEDICINE, HIV, CANCER), THE FOCUS FOR THE NEXT 5 YEARS WILL BE THE ESTABLISHMENT OF A COMPREHENSIVE CANCER CENTER THAT IS POSITIONED TO APPLY FOR NCI DESIGNATION IN 2016-2020, AND THE ESTABLISHMENT OF AN INSTITUTE OF TRANSFUSION MEDICINE (DETAILS STILL BEING WORKED ON). THE CENTER FOR CANCER AND IMMUNOLOGY RESEARCH HAD $6,200,117 IN EXPENSES FY 2011. MOLECULAR PHYSIOLOGY: THE CMPR WAS ESTABLISHED IN FEBRUARY 2009 TO FURTHER THE UNDERSTANDING OF THE MOLECULAR/PHYSIOLOGICAL PATHWAYS INVOLVED IN THE PATHOGENESIS, TREATMENT AND PREVENTION OF CARDIOVASCULAR AND RENAL DISEASES IN CHILDREN AND YOUNG ADULTS. THE CMPR IS COMPOSED OF TWO DIVISIONS, ONE HEADED BY DR. PATRICIO RAY AND THE OTHER BY DR. PEDRO A. JOSE. DR. RAY'S GROUP STUDIES HIV-NEPHROPATHY AND OTHER RENAL DISEASES, SUCH AS THOSE CAUSED BY FLUID AND ELECTROLYTE DISORDERS, ESPECIALLY THE HYPERTENSION INDUCED BY CHRONIC POTASSIUM DEPRIVATION IN YOUNG ANIMAL MODELS. DR. JOSE'S GROUP IS DIVIDED INTO THEMATIC GROUPS, I.E., 1) OXIDATIVE STRESS AND HYPERTENSION, 2) INFLAMMATION IN HYPERTENSION, OBESITY, AND METABOLIC SYNDROME, 3) SODIUM TRANSPORTERS AND HYPERTENSION, 4) G PROTEIN-COUPLED RECEPTOR KINASES AND HYPERTENSION, 5) SALT SENSITIVITY, 6) VASCULAR REACTIVITY AND HYPERTENSION, 7) EPITHELIAL MESENCHYMAL TRANSITION, 8) BIOMARKERS OF RENAL DISEASE, AND 9) GASTRO-INTESTINAL RENAL AXIS. A CENTRAL FOCUS OF CMPR IS DETERMINING THE GENETIC CAUSES OF RENAL DISEASES AND ESSENTIAL HYPERTENSION AND SALT-SENSITIVITY WITH THE AIM OF PROMOTING THE DEVELOPMENT OF DIAGNOSTIC AND THERAPEUTIC STRATEGIES THAT ARE TAILOR-MADE FOR THE INDIVIDUAL. THE APPROACH OF USING MOLECULAR DIAGNOSTICS AND ACCOMPANYING THERAPEUTIC STRATEGIES FITS WITH TODAY'S PHARMACEUTICAL FOCUS ON PHARMACOGENOMICS OR THERAPEUTICS ON PERSONALIZED MEDICINE. THIS WILL BE ACHIEVED BY THE USE OF PROTEIN AND RENAL TUBULE CELL BIOMARKERS THAT PREDICT WHOLE BODY PHENOTYPE REGARDING HYPERTENSION AND SALT SENSITIVITY. THE CMPR FOCUSES ITS EFFORTS ON THE GROUPS THAT SUFFER THE MOST FROM RENAL DISEASE AND HYPERTENSION BECAUSE OF ACQUIRED DISEASES IN CHILDHOOD (FLUID AND ELECTROLYTE DISORDERS) AND GENETIC PREDISPOSITION, EXACERBATED BY EXCESSIVE SODIUM AND CALORIE CONSUMPTION AND STRESS. THE CENTER FOR MOLECULAR PHYSIOLOGY RESEARCH HAD $4,796,989 IN EXPENSES FY 2011. SHEIKH ZAYED INSTITUTE FOR PEDIATRIC SURGICAL INNOVATION: LAUNCHED IN SEPTEMBER 2009, THE SHEIKH ZAYED INSTITUTE FOR PEDIATRIC SURGICAL INNOVATION AT CHILDREN'S NATIONAL REDEFINES WHAT IS POSSIBLE IN SURGERY FOR CHILDREN BY COMBINING RESEARCH AND CLINICAL EXPERTISE INTO ONE COLLABORATIVE TEAM. THE INSTITUTE DEVELOPS KNOWLEDGE, TOOLS, AND PROCEDURES THAT BENEFIT CHILDREN IN THE WASHINGTON DC REGION, ACROSS THE COUNTRY, AND AROUND THE WORLD. THE PRIMARY FOCUS IS TO LEARN FROM TODAY'S SURGERIES, AND CONDUCT INNOVATIVE RESEARCH BASED ON THAT KNOWLEDGE TO IMPROVE PEDIATRIC SURGERY FOR CHILDREN. THOUGH THE RESEARCH SPACE OFFICIALLY OPENED IN APRIL 2011, ALL FOUR INITIATIVES (PAIN MEDICINE; SYSTEMS BIOLOGY AND PERSONAL MEDICINE; BIOENGINEERING; AND IMMUNOLOGY) HAD SIGNIFICANT RESEARCH PROJECTS UNDERWAY PRIOR TO MOVING INTO THE INSTITUTE'S OFFICIAL HOME. BY THE END OF FY 11, THE INSTITUTE HAD COLLECTIVELY PUBLISHED MORE THAN 25 STUDIES IN PEER REVIEWED JOURNALS ACROSS A VARIETY OF SCIENTIFIC AREAS. THE SHEIKH ZAYED INSTITUTE FOR PEDIATRIC SURGICAL INNOVATION HAD $2,536,522 IN EXPENSES FY 2011.
PART VI, LINE 6, 7A, AND 7B:
CHILDREN'S NATIONAL MEDICAL CENTER IS THE SOLE MEMBER OF CHILDREN'S RESEARCH INSTITUTE AND HAS THE RIGHT TO ELECT DIRECTORS OF CHILDREN'S RESEARCH INSTITUTE. THE ARTICLES AND BY-LAWS OF CHILDREN'S RESEARCH INSTITUTE DESCRIBE CERTAIN RIGHTS RESERVED TO THE SOLE MEMBER.
PART VI, LINE 11B:
THE RELEVANT COMMITTEES OF THE ORGANIZATION AND ITS PARENT ORGANIZATION, CHILDREN'S NATIONAL MEDICAL CENTER, REVIEW APPLICABLE PORTIONS OF THE 990. THE LEGAL AFFAIRS AND AUDIT COMMITTEE REVIEW THE FINANCIAL DISCLOSURES, THE NOMINATING AND GOVERNANCE COMMITTEE REVIEW THE GOVERNANCE SECTIONS AND THE PUBLIC BENEFIT SECTIONS, AND THE EXECUTIVE COMPENSATION COMMITTEE REVIEW THE COMPENSATION DISCLOSURES. THE COMPLETED FORM 990 IS THEN MADE AVAILABLE TO THE ENTIRE GOVERNING BOARD OF THE CHILDREN'S RESEARCH INSTITUTE BEFORE FILING.
PART VI, LINE 12C:
CHILDREN'S RESEARCH INSTITUTE ("CRI") REQUIRES THAT EACH OFFICER, DIRECTOR, AND KEY EMPLOYEE COMPLETE A CONFLICT OF INTEREST FORM AT LEAST EVERY YEAR. IN ADDITION EACH OFFICER, DIRECTOR, AND KEY EMPLOYEE IS INSTRUCTED AND REQUIRED TO AMEND THE CONFLICT OF INTEREST FORM IMMEDIATELY UPON A CHANGE IN STATUS OF ANY OF THE QUESTIONS ON THE FORM. THESE FORMS ARE REVIEWED ANNUALLY BY THE CHIEF LEGAL OFFICER AND CONFLICTS AND INTERESTS ARE NOTED. THE CHILDREN'S RESEARCH INSTITUTE BOARD MAKES A DETERMINATION, BASED ON THE RECOMMENDATION OF THE CHIEF LEGAL OFFICER AS TO WHICH PERSONS SHOULD BE CONSIDERED "INTERESTED PARTIES" BASED ON THE CRITERIA SET FORTH IN THE BOARD'S GOVERNANCE POLICY. CRI FORMALLY ADOPTED THE CONFLICT OF INTEREST POLICY OF ITS PARENT, CHILDREN'S NATIONAL MEDICAL CENTER, DURING ITS MAY-JUNE 2011 BOARD MEETINGS.
PART VI, LINES 13 & 14:
CHILDREN'S RESEARCH INSTITUTE ("CRI") IS GOVERNED BY THE POLICIES OF ITS PARENT, CHILDREN'S NATIONAL MEDICAL CENTER ("CNMC"). THESE POLICIES INCLUDE A WRITTEN WHISTLEBLOWER POLICY AND A WRITTEN DOCUMENT RETENTION AND DESTRUCTION POLICY. CRI'S BOARD FORMALLY ADOPTED CNMC'S WHISTELBLOWER AND DOCUMENT RETENTION AND DESTRUCTION POLICIES DURING ITS MAY-JUNE 2011 MEETINGS.
PART VI, LINES 15A AND 15B:
CHILDREN'S RESEARCH INSTITUTE ("CRI") RELIES ON ITS PARENT, CHILDREN'S NATIONAL MEDICAL CENTER, TO DETERMINE COMPENSATION FOR CRI'S PRESIDENT. CHILDREN'S NATIONAL MEDICAL CENTER USED A COMPENSATION COMMITTEE, WRITTEN EMPLOYMENT CONTRACT, INDEPENDENT COMPENSATION CONSULTANT, COMPENSATION SURVEY OR STUDY, AND APPROVAL BY THE BOARD OR COMPENSATION COMMITTEE.
PART VI, LINE 19:
CHILDREN'S RESEARCH INSTITUTE MAKES ITS GOVERNING DOCUMENTS, CONFLICT OF INTEREST POLICY, AND FINANCIAL STATEMENTS AVAILABLE UPON REQUEST.
HOURS DEVOTED FOR RELATED ORGANIZATION
FORM 990 PART VII
NAME:MARK L BATSHAW MD TITLE:BD MEM/EVP/CHIEF ACADEMIC OFF HOURS:11