Department of the Treasury Internal Revenue Service
Public Charity Status and Public Support
Complete if the organization is a section 501(c)(3) organization or a section
4947(a)(1) nonexempt charitable trust.
Attach to Form 990 or Form 990-EZ. See separate instructions.
OMB No. 1545-0047
2010
Open to Public Inspection
Name of the organization
THE JACKSON LABORATORY
Employer identification number
01-0211513
Part I
Reason for Public Charity Status
(All organizations must complete this part.) See instructions
The organization is not a private foundation because it is: (For lines 1 through 11, check only one box.)
1
2
3
4
5
section 170(b)(1)(A)(iv). (Complete Part II.)
6
7
8
9
receipts from activities related to its exempt functions—subject to certain exceptions, and (2) no more than 331/3% of
its support from gross investment income and unrelated business taxable income (less section 511 tax) from businesses
acquired by the organization after June 30, 1975. See section 509(a)(2). (Complete Part III.)
10
11
e
By checking this box, I certify that the organization is not controlled directly or indirectly by one or more disqualified persons other than foundation managers and other than one or more publicly supported organizations described in section 509(a)(1) or section 509(a)(2).
f
If the organization received a written determination from the IRS that it is a Type I, Type II or Type III supporting organization, check this box
..................................................
g
Since August 17, 2006, has the organization accepted any gift or contribution from any of the following persons?
(i) a person who directly or indirectly controls, either alone or together with persons described in (ii)
Yes
No
and (iii) below, the governing body of the the supported organization?
................
11g(i)
No
(ii)
a family member of a person described in (i) above?
......................
11g(ii)
No
(iii)
a 35% controlled entity of a person described in (i) or (ii) above?
................
11g(iii)
No
h
Provide the following information about the supported organization(s).
(i) Name of supported organization
(ii) EIN
(iii) Type of organization (described on lines 1- 9 above or IRC section (see instructions))
(iv) Is the organization in col. (i) listed in your governing document?
(v) Did you notify the organization in col. (i) of your support?
(vi) Is the organization in col. (i) organized in the U.S.?
(vii) Amount of support?
Yes
No
Yes
No
Yes
No
Total
For Paperwork Reduction Act Notice, see the Instructions for Form 990.
Cat. No. 11285F
Schedule A (Form 990 or 990-EZ) 2010
Schedule A (Form 990 or 990-EZ) 2010
Page 2
Part II
Support Schedule for Organizations Described in IRC 170(b)(1)(A)(iv) and 170(b)(1)(A)(vi) (Complete only if you checked the box on line 5, 7, or 8 of Part I or if the
organization failed to qualify under Part III. If the organization fails to
qualify under the tests listed below, please complete Part III.)
Section A. Public Support
Calendar year(or fiscal year beginning in)
(a) 2006
(b) 2007
(c) 2008
(d) 2009
(e) 2010
(f) Total
1
Gifts, grants, contributions, and membership fees received. (Do not include any "unusual grants.") ....
69,277,727
66,103,830
66,396,577
69,040,663
73,823,292
344,642,089
2
Tax revenues levied for the organization's benefit and either paid to or expended on its behalf.......
3
The value of services or facilities furnished by a governmental unit to the organization without charge..
4
Total. Add lines 1 through 3..
69,277,727
66,103,830
66,396,577
69,040,663
73,823,292
344,642,089
5
The portion of total contributions by each person (other than a governmental unit or publicly supported organization) included
on line 1 that exceeds 2% of the amount shown on line 11, column (f)..
6
Public Support. Subtract line 5 from line 4.
344,642,089
Section B. Total Support
Calendar year(or fiscal year beginning in)
(a) 2006
(b) 2007
(c) 2008
(d) 2009
(e) 2010
(f) Total
7
Amounts from line 4..
69,277,727
66,103,830
66,396,577
69,040,663
73,823,292
344,642,089
8
Gross income from interest, dividends, payments received on securities loans, rents, royalties and income from similar sources..
3,880,882
4,569,075
4,253,688
3,370,975
2,954,194
19,028,814
9
Net income from unrelated business activities, whether or not the business is regularly carried on..
97,530
19,815
0
21,308
48,973
187,626
10
Other income. (Explain in Part IV.) Do not include gain or loss from the sale of capital assets..
11
Total support (Add lines 7 through 10).
363,858,529
12
Gross receipts from related activities, etc. (See instructions.)
..................
12
454,422,499
13
First Five Years
If the Form 990 is for the organization's first, second, third, fourth, or fifth tax year as a 501(c)(3) organization,
check this box and stop here..........................................
Section C. Computation of Public Support Percentage
14
Public Support Percentage for 2010 (line 6 column (f) divided by line 11 column (f))
.........
14
94.719 %
15
Public Support Percentage for 2009 Schedule A, Part II, line 14
...............
15
94.651 %
16a
33 1/3% support test—2010.
If the organization did not check the box on line 13, and line 14 is 33 1/3% or more, check this box
and stop here. The organization qualifies as a publicly supported organization
......................
b
33 1/3% support test—2009.
If the organization did not check the box on line 13 or 16a, and line 15 is 33 1/3% or more, check this
box and stop here. The organization qualifies as a publicly supported organization
.....................
17a
10%-facts-and-circumstances test—2010.
If the organization did not check a box on line 13, 16a, or 16b and line 14
is 10% or more, and if the organization meets the "facts and circumstances" test, check this box and stop here. Explain
in Part IV how the organization meets the "facts and circumstances" test. The organization qualifies as a publicly supported
organization
..................................................
b
10%-facts-and-circumstances test—2009.
If the organization did not check a box on line 13, 16a, 16b, or 17a and line
15 is 10% or more, and if the organization meets the "facts and circumstances" test, check this box and stop here.
Explain in Part IV how the organization meets the "facts and circumstances" test. The organization qualifies as a publicly supported organization
..............................................
18
Private Foundation
If the organization did not check a box on line 13, 16a, 16b, 17a or 17b, check this box and see
instructions
...................................................
Schedule A (Form 990 or 990-EZ) 2010
Schedule A (Form 990 or 990-EZ) 2010
Page 3
Part III
Support Schedule for Organizations Described in IRC 509(a)(2) (Complete only if you checked the box on line 9 of Part I or if the organization
failed to qualify under Part II. If the organization fails to qualify under
the tests listed below, please complete Part II.)
Section A. Public Support
Calendar year(or fiscal year beginning in)
(a) 2006
(b) 2007
(c) 2008
(d) 2009
(e) 2010
(f) Total
1
Gifts, grants, contributions, and membership fees received. (Do not include any "unusual grants.") .
2
Gross receipts from admissions, merchandise sold or services performed, or facilities furnished in any activity that is related to the organization's tax-exempt purpose......
3
Gross receipts from activities that are not an unrelated trade or business under section 513..
4
Tax revenues levied for the organization's benefit and either paid to or expended on its behalf...
5
The value of services or facilities furnished by a governmental unit to the organization without charge..
6
Total. Add lines 1 through 5.
7a
Amounts included on lines 1, 2, and 3 received from disqualified persons...
b
Amounts included on lines 2 and 3 received from other than disqualified persons that exceed the greater of $5,000 or 1% of the amount on line 13 for the year.
c
Add lines 7a and 7b..
8
Public Support (Subtract line 7c from line 6.)
Section B. Total Support
Calendar year (or fiscal year beginning in)
(a) 2006
(b) 2007
(c) 2008
(d) 2009
(e) 2010
(f) Total
9
Amounts from line 6...
10a
Gross income from interest, dividends, payments received on securities loans, rents, royalties and income from similar sources..
b
Unrelated business taxable income (less section 511 taxes) from businesses acquired after June 30, 1975.
c
Add lines 10a and 10b.
11
Net income from unrelated business activities not included in line 10b, whether or not the business is regularly carried on.
12
Other income. Do not include gain or loss from the sale of capital assets (Explain in Part IV.)
13
Total support (Add lines 9, 10c, 11 and 12.).
14
First Five Years
If the Form 990 is for the organization's first, second, third, fourth, or fifth tax year as a 501(c)(3) organization,
check this box and stop here.............................................
Section C. Computation of Public Support Percentage
15
Public Support Percentage for 2010 (line 8 column (f) divided by line 13 column (f))
.........
15
16
Public support percentage from 2009 Schedule A, Part III, line 15
...............
16
Section D. Computation of Investment Income Percentage
17
Investment income percentage for 2010 (line 10c column (f) divided by line 13 column (f))
......
17
18
Investment income percentage from 2009 Schedule A, Part III, line 17
.............
18
19a
33 1/3% support tests—2010.
If the organization did not check the box on line 14, and line 15 is more than 33 1/3% and line 17 is not more than 33 1/3%, check this box and stop here. The organization qualifies as a publicly supported organization
..........
b
33 1/3% support tests—2009.
If the organization did not check a box on line 14 or line 19a, and line 16 is more than 33 1/3% and line 18 is not more than 33 1/3%, check this box and stop here. The organization qualifies as a publicly supported organization
....
20
Private Foundation
If the organization did not check a box on line 14, 19a or 19b, check this box and see instructions
.....
Schedule A (Form 990 or 990-EZ) 2010
Schedule A (Form 990 or 990-EZ) 2010
Page 4
Part IV
Supplemental Information.
Supplemental Information. Complete this part to provide the explanation required by Part II, line 10; Part II, line 17a or 17b; or Part III, line 12. Also complete this part for any additional information. (See instructions).
Facts And Circumstances Test
Explanation
Schedule A (Form 990 or 990-EZ) 2010
Additional Data
Software ID:
Software Version:
-
TIN:
SCHEDULE O (Form 990 or 990-EZ)
Department of the Treasury Internal Revenue Service
Supplemental Information to Form 990 or 990-EZ
Complete to provide information for responses to specific questions on
Form 990 or to provide any additional information.
Attach to Form 990 or 990-EZ.
OMB No. 1545-0047
2010
Open to Public Inspection
Name of the organization
THE JACKSON LABORATORY
Employer identification number
01-0211513
Identifier
Return Reference
Explanation
ORGANIZATION'S MISSION
FORM 990, PART III, LINE 1
THE MISSION OF THE LABORATORY IS THREEFOLD: 1.) CONDUCTING BASIC BIOMEDICAL RESEARCH; 2.) TRAINING AND EDUCATING SCIENTISTS WORLDWIDE; 3.) PROVIDING GENETIC RESOURCES TO THE GLOBAL SCIENTIFIC COMMUNITY. THE PURPOSE OF THE LABORATORY IS TO INCREASE THE KNOWLEDGE OF DEVELOPMENT, GROWTH, REPRODUCTION, PHYSIOLOGICAL, AND INBORN ALIMENTS THROUGH RESEARCH WITH GENETICALLY DEFINED EXPERIMENTAL ANIMALS.
PROGRAM SERVICES
FORM 990, PART III, LINE 4A-4C
4A. GENETIC RESOURCES THE JACKSON LABORATORY GENERATES AND MAINTAINS OPEN-SOURCE DATABASES THAT ARE AVAILABLE TO THE WORLDWIDE RESEARCH COMMUNITY, DRIVING DISCOVERY IN CANCER, DIABETES, OSTEOPOROSIS, ALZHEIMER'S DISEASE AND MANY OTHER AREAS CRITICAL TO HUMAN HEALTH. THROUGHOUT FISCAL YEAR 2011, THESE DATABASES EXPERIENCED CLOSE TO 9 MILLION "HITS" PER WEEK. THE LABORATORY'S MOUSE REPOSITORY OFFERED A PORTFOLIO OF OVER 2,500 TARGETED AND 1,200 TRANSGENIC MUTANT MOUSE LINES. THESE INCLUDED A WIDE SELECTION OF STRAINS GENETICALLY ENGINEERED AS MOUSE MODELS OF HUMAN DISEASES, AMONG THEM CANCER, HEART DISEASE, ALZHEIMER'S DISEASE, ALS, DIABETES, PARKINSON'S DISEASE, SPINAL MUSCULAR ATROPHY, HUNTINGTON'S DISEASE AND VARIOUS AUTOIMMUNE DISEASES. TO INCREASE THE NUMBER OF NEW CANCER DRUGS THAT ARE BOTH SAFE AND EFFECTIVE IN PATIENTS, THE JACKSON LABORATORY IS PARTNERING WITH THE UC DAVIS CANCER CENTER AND THE NATIONAL CANCER INSTITUTE'S (NCI) CENTER FOR ADVANCED PRECLINICAL RESEARCH (CAPR), ALL UNDER THE UMBRELLA OF NCI'S ADVANCED TECHNOLOGY PARTNERSHIPS INITIATIVE (ATPI). UNDER THE PARTNERSHIP, THE JACKSON LABORATORY SUCCESSFULLY DEVELOPED A GENETICALLY ENGINEERED MOUSE MODEL CAPABLE OF ACCEPTING THE ENGRAFTMENT OF HUMAN TISSUE. 4B. RESEARCH PROFESSOR JOHN EPPIG, A PIONEER IN DEVELOPMENTAL AND REPRODUCTIVE BIOLOGY, WAS ELECTED TO THE NATIONAL ACADEMY OF SCIENCES, ONE OF THE TOP HONORS IN AMERICAN SCIENCE. A JACKSON LABORATORY RESEARCH TEAM LED BY PROFESSOR SIMON JOHN AND COLLABORATORS REPORTED THEY HAVE DESIGNED AN ANALYSIS TECHNIQUE THAT DETECTS EARLY STAGES OF GLAUCOMA IN MICE, AND HAVE SUCCESSFULLY BLOCKED THE DISEASE BY TARGETING SOME OF THE MOLECULAR EVENTS IN THOSE EARLY STAGES. DR. JOHN'S LABORATORY ALSO REPORTED THEIR FINDING THAT RNA GRANULES-KEY PLAYERS IN MESSENGER RNA (MRNA) PROCESSING-CAN AFFECT EYE DEVELOPMENT, LEADING TO JUVENILE CATARACTS AND GLAUCOMA IN HUMANS AND MICE, AND THEIR DISCOVERY OF A GENE IMPLICATED IN AN ACUTE AND SEVERE FORM OF GLAUCOMA KNOWN AS ANGLE-CLOSURE GLAUCOMA. JACKSON LABORATORY PROFESSOR GARY CHURCHILL AND COLLABORATORS AT THE UNIVERSITY OF NORTH CAROLINA, CHAPEL HILL, CREATED A GENOME-WIDE, HIGH-RESOLUTION MAP OF MOST OF THE INBRED MOUSE STRAINS USED TODAY. THEIR CONCLUSION, PUBLISHED IN NATURE GENETICS: MOST OF THE MICE IN USE TODAY REPRESENT ONLY LIMITED GENETIC DIVERSITY, WHICH COULD BE SIGNIFICANTLY EXPANDED WITH THE ADDITION OF MORE WILD MOUSE POPULATIONS. RESEARCHERS AT THE JACKSON LABORATORY LED BY ASSISTANT PROFESSOR ZHONG-WEI ZHANG HAVE DISCOVERED A FACTOR IN SYNAPSE BUILDING, ALSO SHOWING THAT THE INTRICATE PROCESSES OF SYNAPSE BUILDING AND PRUNING OCCUR INDEPENDENT OF EACH OTHER. A RESEARCH TEAM INCLUDING JACKSON LABORATORY PROFESSOR DERRY ROOPENIAN SHOWED THAT BY PAIRING WITH A SPECIAL RECEPTOR, KNOWN AS FCRN, ANTIBODIES CAN ENTER CELLS THAT HAVE BEEN INVADED BY INFLUENZA VIRUS AND SHUT DOWN THEIR REPLICATION MACHINERY. A BETTER UNDERSTANDING OF HOW-AND WHERE-THE ANTIBODIES FIGHT VIRUSES IS IMPORTANT FOR DESIGNING NEW AND MORE EFFECTIVE VACCINES AND ANTIBODY-BASED THERAPIES. JACKSON LABORATORY RESEARCH SCIENTIST CAT LUTZ, PH.D., AND COLLABORATORS AT COLUMBIA UNIVERSITY AND OTHER LABORATORIES, DEMONSTRATED A NEW APPROACH TO TREATING THE DEVASTATING NEUROMUSCULAR DISEASE KNOWN AS SPINAL MUSCULAR ATROPHY (SMA). WORKING WITH A NEW MOUSE MODEL OF SMA, THE RESEARCHERS REDUCED THE SYMPTOMS OF THE DISEASE BY RESTORING LEVELS OF A PROTEIN CALLED SMN. 4C. TRAINING THE JACKSON LABORATORY PROVIDED 29 COURSES, CONFERENCES, SEMINARS AND WORKSHOP EVENTS. THESE UNIQUE EDUCATIONAL OPPORTUNITIES ATTRACTED 691 PARTICIPANTS FROM THROUGHOUT THE NATIONAL AND INTERNATIONAL RESEARCH COMMUNITY, AFFORDING THEM WITH OPPORTUNITIES TO TRADE INSIGHTS WITH 404 FACULTY MEMBERS. THE JACKSON LABORATORY HAS OFFERED SCHOOL-YEAR INTERNSHIPS TO HIGH SCHOOL STUDENTS FROM REGIONAL HIGH SCHOOLS SINCE 1993. THIS PROGRAM IN FISCAL YEAR 2011 ATTRACTED EIGHT STUDENTS. THE LABORATORY'S COLLEGE INTERNSHIP PROGRAM ALSO PROVIDED ON-CAMPUS, SEMESTER-LONG INDEPENDENT RESEARCH PROJECTS TO FOUR STUDENTS. YET ANOTHER HAND-ON PROGRAM FOR SCIENCE TEACHERS ATTRACTED THREE PARTICIPANTS. THE JACKSON LABORATORY'S HISTORIC SUMMER STUDENT PROGRAM HAD 38 TALENTED PARTICIPANTS. THE NATIONALLY RENOWNED PROGRAM PROVIDES HIGH SCHOOL AND COLLEGE STUDENTS WITH AN OPPORTUNITY TO CONDUCT INDEPENDENT RESEARCH UNDER THE GUIDANCE OF STAFF SCIENTISTS. MORE THAN 2,200 STUDENTS, INCLUDING THREE NOBEL LAUREATES, HAVE PARTICIPATED IN THE PROGRAM. MOST ALUMNI GO ON TO CAREERS IN MEDICINE OR RESEARCH. COMMITMENT TO EDUCATIONAL OUTREACH EXTENDS INTO REGIONAL ELEMENTARY SCHOOLS. FISCAL YEAR 2011 SAW THE CONTINUATION OF THE POPULAR, LITERALLY HANDS-ON -BACTERIOLOGY COURSE IN WHICH SECOND-GRADERS LEARN ABOUT THE COMMON GERMS THAT LIVE ON THE PALMS OF THEIR HANDS. THESE COURSES ARE CONDUCTED PRIMARILY WITH THE USE OF RESEARCH STAFF VOLUNTEERS, INCLUDING FACULTY MEMBERS, POSTDOCTORAL STUDENTS AND RESEARCH ASSISTANTS.
FORM 990 REVIEW PROCESS
PART VI, SECTION B, QUESTION 11A
THE AUDIT COMMITTEE OF THE JACKSON LABORATORY'S BOARD OF TRUSTEES REVIEWS A DRAFT COPY OF THE IRS FORM 990 BEFORE IT IS PROVIDED TO THE BOARD OF TRUSTEES. AFTER REVIEW, THE IRS FORM 990 IS FINALIZED AND FILED.
CONFLICT OF INTEREST POLICY
PART VI, SECTION B, QUESTION 12C
THE JACKSON LABORATORY ANNUALLY PROVIDES ALL OFFICERS, BOARD MEMBERS AND KEY EMPLOYEES WITH A CONFLICT OF INTEREST, CODE OF ETHICS AND DISCLOSURE QUESTIONNAIRE ACCOMPANIED WITH COPIES OF ALL RELATED POLICIES. THE DISCLOSURE AND COMPLIANCE ATTESTATIONS ARE RETURNED TO TRUSTEE RELATIONS, WHERE THEY ARE RECORDED AND TALLIED FOR COMPLETENESS. ANY ISSUES NOTED ARE REFERRED TO THE AUDIT COMMITTEE. THE CHIEF FINANCIAL OFFICER ALSO REVIEWS THE RESPONSES TO IDENTIFY ANY ITEMS THAT REQUIRE DISCLOSURE.
COMPENSATION POLICY
PART VI, SECTION B, QUESTION 15B
THE COMPENSATION AND HUMAN RESOUCES COMMMITTEE OF THE BOARD OF TRUSTEES SETS COMPENSATION AND BENEFITS FOR THE CHIEF EXECUTIVE OFFICER, EXECUTIVE VICE PRESIDENT AND CHIEF OPERATING OFFICER, THE ASSOCIATE DIRECTOR AND CHAIR OF RESEARCH, THE VICE PRESIDENT FOR ADVANCEMENT AND EXTERNAL RELATIONS, THE CHIEF FINANCIAL OFFICER AND EQUIVALENT POSITIONS AS WELL AS ANY OTHER EMPLOYEES OF THE LABORATORY WHO WOULD BE CONSIDERED 'INSIDERS' OR 'DISQUALIFIED PERSONS' WITHIN THE MEANING OF THE INTERMEDIATE SANCTIONS RULES UNDER THE INTERNAL REVENUE CODE. MEMBERS OF THE COMMITTEEE ARE INDEPENDENT TRUSTEES SELECTED BY THE CHAIR OF THE BOARD OF TRUSTEES. THE COMMITTEE IS GUIDED BY MARKET DATA OF COMPENSATION PACKAGES FOR SIMILAR POSITIONS IN COMPARABLE ORGANIZATIONS. MARKET DATA IS PREPARED FOR THE COMMITTEE BY AN EXTERNAL EXECUTIVE COMPENSATION FIRM WHICH CONSIDERS COMPENSATION INFORMATION REPORTED IN FORM 990'S OF COMPARABLE ORGANIZATIONS AND THE RESULTS OF RECOGNIZED COMPENSATION SURVEYS. THE SENIOR DIRECTOR OF HUMAN RESOURCES IS AVAILABLE TO THE COMMITTEE TO PROVIDE ANY OTHER DATA NEEDED. THE CEO MEETS WITH THE COMMITTEE AT LEAST ANNUALLY TO PROVIDE THE COMMITTEE MEMBERS WITH ANNUAL PERFORMANCE REVIEWS OF HIS REPORTS. THE COMMITTEE'S REVIEW PROCESS AND RESULTS ARE DOCUMENTED IN MINUTES OF THE MEETINGS.
PUBLIC DISCLOSURE
PART VI, SECTION C, QUESTION 19
THE ORGANIZATION'S FORM 990 IS AVAILABLE ON WWW.GUIDESTAR.ORG AND ON THE ORGANIZATION'S PUBLIC WEBSITE JAX.ORG.
OTHER CHANGES IN NET ASSETS
PART XI, LINE 5
UNREALIZED GAIN 321,353 UNREALIZED LOSS ON INTEREST RATE SWAPS (335,174) CHANGES IN ACTUARIAL ASSUMPTIONS 282,948 ROUNDING 293 TOTAL 269,420
For Paperwork Reduction Act Notice, see the Instructions for Form 990 or 990-EZ.