TY 2011 Form 990

Do not include amounts reported on lines 6b, 7b, 8b, 9b, and 10b of Part VIII.	(A) Total expenses	(B) Program service expenses	(C) Management and general expenses	(D) Fundraising expenses
1	Grants and other assistance to governments and organizations in the United States. See Part IV, line 21	0
2	Grants and other assistance to individuals in the United States. See Part IV, line 22	1,151,122	1,151,122
3	Grants and other assistance to governments, organizations, and individuals outside the United States. See Part IV, lines 15 and 16	0
4	Benefits paid to or for members	0
5	Compensation of current officers, directors, trustees, and key employees ....	2,178,666	1,960,799	217,867
6	Compensation not included above, to disqualified persons (as defined under section 4958(f)(1)) and persons described in section 4958(c)(3)(B) ....	0
7	Other salaries and wages	19,138,217	17,224,395	1,913,822
8	Pension plan accruals and contributions (include section 401(k) and 403(b) employer contributions) ....	2,829,722	2,546,750	282,972
9	Other employee benefits .......	3,166,612	2,849,951	316,661
10	Payroll taxes ...........	1,306,897	1,176,207	130,690
11	Fees for services (non-employees):
a	Management ......	0
b	Legal .........	54,294		54,294
c	Accounting ...........	10,200		10,200
d	Lobbying ...........	0
e	Professional fundraising. See Part IV, line 17..	0
f	Investment management fees ......	0
g	Other ..........	1,383,476	1,245,128	138,348
12	Advertising and promotion ....	0
13	Office expenses .......	340,382	306,344	34,038
14	Information technology ......	399,471	359,524	39,947
15	Royalties ..	173,624	156,262	17,362
16	Occupancy ...........	2,323,812	2,091,431	232,381
17	Travel ............	656,413	590,772	65,641
18	Payments of travel or entertainment expenses for any federal, state, or local public officials ......	0
19	Conferences, conventions, and meetings ....	703,752	633,377	70,375
20	Interest ...........	0
21	Payments to affiliates .......	0
22	Depreciation, depletion, and amortization .....	11,724,175	10,551,758	1,172,417
23	Insurance ..............	0
24	Other expenses. Itemize expenses not covered above (List miscellaneous expenses in line 24f. If line 24f amount exceeds 10% of line 25, column (A) amount, list line 24f expenses on Schedule O.)
a	COST-SHARING W/RELATED ORG	16,675,992	15,008,393	1,667,599
b	LAB SUPPLIES	6,401,614	5,761,453	640,161
c	NON-CAPITAL EQUIPMENT	678,952	611,057	67,895
d	SCIENTIFIC CONSULTING	383,842	345,458	38,384
e
f	All other expenses	379,040	341,134	37,906
25	Total functional expenses. Add lines 1 through 24f	72,060,275	64,911,315	7,148,960	0
26	Joint costs. Complete this line only if the organization reported in column (B) joint costs from a combined educational campaign and fundraising solicitation. Check here if following SOP 98-2 (ASC 958-720).

Part X Balance Sheet
	1	Cashnon-interest-bearing ..........	2,178,335	1	1,943,474
2	Savings and temporary cash investments .......	0	2	0
3	Pledges and grants receivable, net .........	804,237	3	697,175
4	Accounts receivable, net .........	0	4	0
5	Receivables from current and former officers, directors, trustees, key employees, and highest compensated employees. Complete Part II of
	Schedule L ..........	0	5	0
6	Receivables from other disqualified persons (as defined under section 4958(f)(1)) and persons described in section 4958(c)(3)(B). Complete Part II of
	Schedule L ..........	0	6	0
7	Notes and loans receivable, net .............	0	7	0
8	Inventories for sale or use ..............	349,600	8	349,600
9	Prepaid expenses and deferred charges ............	631,357	9	714,385
10a	Land, buildings, and equipment: cost or other basis. Complete Part VI of Schedule D	10a	313,812,169
b	Less: accumulated depreciation. .....	10b	131,463,800	189,268,370	10c	182,348,369
11	Investments—publicly traded securities ..........	91,159,672	11	86,566,796
12	Investments—other securities. See Part IV, line 11 ......	15,662	12	354,224
13	Investments—program-related. See Part IV, line 11 ..	0	13	0
14	Intangible assets .........	0	14	0
15	Other assets. See Part IV, line 11 ...........	212,236,512	15	202,922,595
16	Total assets. Add lines 1 through 15 (must equal line 34)...	496,643,745	16	475,896,618
	17	Accounts payable and accrued expenses .	5,780,182	17	7,365,107
18	Grants payable ..........	0	18	0
19	Deferred revenue ..........	536,488	19	617,194
20	Tax-exempt bond liabilities ..........	0	20	0
21	Escrow or custodial account liability. Complete Part IV of Schedule D..	0	21	0
22	Payables to current and former officers, directors, trustees, key employees, highest compensated employees, and disqualified
	persons. Complete Part II of Schedule L..........	0	22	0
23	Secured mortgages and notes payable to unrelated third parties ..	0	23	0
24	Unsecured notes and loans payable to unrelated third parties ....	0	24	0
25	Other liabilities (including federal income tax, payables to related third parties, and other liabilities not included on lines 17-24). Complete Part X of Schedule D.....	211,148,145	25	201,700,407
26	Total liabilities. Add lines 17 through 25.....	217,464,815	26	209,682,708
		Organizations that follow SFAS 117, check here and complete lines 27 through 29, and lines 33 and 34.
27	Unrestricted net assets .....	279,178,930	27	266,213,910
28	Temporarily restricted net assets .....	0	28	0
29	Permanently restricted net assets .....	0	29	0
	Organizations that do not follow SFAS 117, check here and complete lines 30 through 34.
30	Capital stock or trust principal, or current funds .....		30
31	Paid-in or capital surplus, or land, building or equipment fund .....		31
32	Retained earnings, endowment, accumulated income, or other funds		32
33	Total net assets or fund balances .....	279,178,930	33	266,213,910
34	Total liabilities and net assets/fund balances .....	496,643,745	34	475,896,618

- TIN:

SCHEDULE A
(Form 990 or 990EZ)

Department of the Treasury
Internal Revenue Service

Public Charity Status and Public Support

Complete if the organization is a section 501(c)(3) organization or a section
4947(a)(1) nonexempt charitable trust.

Attach to Form 990 or Form 990-EZ. right arrow

See separate instructions.

OMB No. 1545-0047

2011

Open to Public
Inspection

Name of the organization

STOWERS INSTITUTE FOR MEDICAL RESEARCH

Employer identification number

20-2993509

Part I

Reason for Public Charity Status (All organizations must complete this part.) See instructions

The organization is not a private foundation because it is: (For lines 1 through 11, check only one box.)

A church, convention of churches, or association of churches. section 170(b)(1)(A)(i).

A school described in section 170(b)(1)(A)(ii). (Attach Schedule E.)

A hospital or a cooperative hospital service organization described in section 170(b)(1)(A)(iii).

A medical research organization operated in conjunction with a hospital described in section 170(b)(1)(A)(iii). Enter the hospital's name, city, and state:

CHILDREN'S MERCY HOSPITAL,

KANSAS CITY, MO

MASSACHUSETTS GENERAL HOSPITAL,

BOSTON, MA

An organization operated for the benefit of a college or university owned or operated by a governmental unit described in

section 170(b)(1)(A)(iv). (Complete Part II.)

A federal, state, or local government or governmental unit described in section 170(b)(1)(A)(v).

An organization that normally receives a substantial part of its support from a governmental unit or from the general public described in

section 170(b)(1)(A)(vi). (Complete Part II.)

A community trust described in section 170(b)(1)(A)(vi). (Complete Part II.)

An organization that normally receives: (1) more than 331/3% of its support from contributions, membership fees, and gross

receipts from activities related to its exempt functions—subject to certain exceptions, and (2) no more than 331/3% of

its support from gross investment income and unrelated business taxable income (less section 511 tax) from businesses

acquired by the organization after June 30, 1975. See section 509(a)(2). (Complete Part III.)

An organization organized and operated exclusively to test for public safety. Seesection 509(a)(4).

An organization organized and operated exclusively for the benefit of, to perform the functions of, or to carry out the purposes of one or more publicly supported organizations described in section 509(a)(1) or section 509(a)(2). See section 509(a)(3). Check the box that describes the type of supporting organization and complete lines 11e through 11h.

Type I

Type II

Type III - Functionally integrated

Type III - Other

By checking this box, I certify that the organization is not controlled directly or indirectly by one or more disqualified persons other than foundation managers and other than one or more publicly supported organizations described in section 509(a)(1) or section 509(a)(2).

If the organization received a written determination from the IRS that it is a Type I, Type II or Type III supporting organization, check this box ..................................................

Since August 17, 2006, has the organization accepted any gift or contribution from any of the
following persons?

(i) a person who directly or indirectly controls, either alone or together with persons described in (ii)

Yes

and (iii) below, the governing body of the the supported organization? ................

11g(i)

(ii) a family member of a person described in (i) above? ......................

11g(ii)

(iii) a 35% controlled entity of a person described in (i) or (ii) above? ................

11g(iii)

Provide the following information about the supported organization(s).

(i) Name of supported organization	(ii) EIN	(iv) Is the organization in col. (i) listed in your governing document?		(v) Did you notify the organization in col. (i) of your support?		(vi) Is the organization in col. (i) organized in the U.S.?		(vii) Amount of support?
(i) Name of supported organization	(ii) EIN	Yes	No	Yes	No	Yes	No	(vii) Amount of support?


Total

For Paperwork Reduction Act Notice, see the Instructions for Form 990.

Cat. No. 11285F

Schedule A (Form 990 or 990-EZ) 2011

Page 2

Part II

Support Schedule for Organizations Described in IRC 170(b)(1)(A)(iv) and 170(b)(1)(A)(vi)
(Complete only if you checked the box on line 5, 7, or 8 of Part I or if the organization failed to qualify under Part III. If the organization fails to qualify under the tests listed below, please complete Part III.)

Section A. Public Support

Calendar year(or fiscal year beginning in)		(a) 2007	(b) 2008	(c) 2009	(d) 2010	(e) 2011	(f) Total
1	Gifts, grants, contributions, and membership fees received. (Do not include any "unusual grants.") ....
2	Tax revenues levied for the organization's benefit and either paid to or expended on its behalf.......
3	The value of services or facilities furnished by a governmental unit to the organization without charge..
4	Total. Add lines 1 through 3..
5	The portion of total contributions by each person (other than a governmental unit or publicly supported organization) included on line 1 that exceeds 2% of the amount shown on line 11, column (f)..
6	Public Support. Subtract line 5 from line 4.

Section B. Total Support

Calendar year(or fiscal year beginning in)		(a) 2007	(b) 2008	(c) 2009	(d) 2010	(e) 2011	(f) Total
7	Amounts from line 4..
8	Gross income from interest, dividends, payments received on securities loans, rents, royalties and income from similar sources..
9	Net income from unrelated business activities, whether or not the business is regularly carried on..
10	Other income. (Explain in Part IV.) Do not include gain or loss from the sale of capital assets..
11	Total support (Add lines 7 through 10).

Gross receipts from related activities, etc. (See instructions.) ..................

First Five Years If the Form 990 is for the organization's first, second, third, fourth, or fifth tax year as a 501(c)(3) organization,
check this box and stop here.......................................... right arrow

Section C. Computation of Public Support Percentage

Public Support Percentage for 2010 (line 6 column (f) divided by line 11 column (f)) .........

Public Support Percentage for 2009 Schedule A, Part II, line 14 ...............

16a

33 1/3% support test—2011. If the organization did not check the box on line 13, and line 14 is 33 1/3% or more, check this box
and stop here. The organization qualifies as a publicly supported organization ...................... right arrow

33 1/3% support test—2010. If the organization did not check the box on line 13 or 16a, and line 15 is 33 1/3% or more, check this
box and stop here. The organization qualifies as a publicly supported organization ..................... right arrow

17a

10%-facts-and-circumstances test—2011. If the organization did not check a box on line 13, 16a, or 16b and line 14
is 10% or more, and if the organization meets the "facts and circumstances" test, check this box and stop here. Explain
in Part IV how the organization meets the "facts and circumstances" test. The organization qualifies as a publicly supported
organization .................................................. right arrow

10%-facts-and-circumstances test—2010. If the organization did not check a box on line 13, 16a, 16b, or 17a and line
15 is 10% or more, and if the organization meets the "facts and circumstances" test, check this box and stop here.
Explain in Part IV how the organization meets the "facts and circumstances" test. The organization qualifies as a publicly
supported organization .............................................. right arrow

Private Foundation If the organization did not check a box on line 13, 16a, 16b, 17a or 17b, check this box and see
instructions ................................................... right arrow

Schedule A (Form 990 or 990-EZ) 2011

Page 3

Part III

Support Schedule for Organizations Described in IRC 509(a)(2)
(Complete only if you checked the box on line 9 of Part I or if the organization failed to qualify under Part II. If the organization fails to qualify under the tests listed below, please complete Part II.)

Section A. Public Support

Calendar year(or fiscal year beginning in)		(a) 2007	(b) 2008	(c) 2009	(d) 2010	(e) 2011	(f) Total
1	Gifts, grants, contributions, and membership fees received. (Do not include any "unusual grants.") .
2	Gross receipts from admissions, merchandise sold or services performed, or facilities furnished in any activity that is related to the organization's tax-exempt purpose......
3	Gross receipts from activities that are not an unrelated trade or business under section 513..
4	Tax revenues levied for the organization's benefit and either paid to or expended on its behalf...
5	The value of services or facilities furnished by a governmental unit to the organization without charge..
6	Total. Add lines 1 through 5.
7a	Amounts included on lines 1, 2, and 3 received from disqualified persons...
b	Amounts included on lines 2 and 3 received from other than disqualified persons that exceed the greater of $5,000 or 1% of the amount on line 13 for the year.
c	Add lines 7a and 7b..
8	Public Support (Subtract line 7c from line 6.)

Section B. Total Support

Calendar year (or fiscal year beginning in)		(a) 2007	(b) 2008	(c) 2009	(d) 2010	(e) 2011	(f) Total
9	Amounts from line 6...
10a	Gross income from interest, dividends, payments received on securities loans, rents, royalties and income from similar sources..
b	Unrelated business taxable income (less section 511 taxes) from businesses acquired after June 30, 1975.
c	Add lines 10a and 10b.
11	Net income from unrelated business activities not included in line 10b, whether or not the business is regularly carried on.
12	Other income. Do not include gain or loss from the sale of capital assets (Explain in Part IV.)
13	Total support (Add lines 9, 10c, 11 and 12.).

Section C. Computation of Public Support Percentage

Public Support Percentage for 2011 (line 8 column (f) divided by line 13 column (f)) .........

Public support percentage from 2010 Schedule A, Part III, line 15 ...............

Section D. Computation of Investment Income Percentage

Investment income percentage for 2011 (line 10c column (f) divided by line 13 column (f)) ......

Investment income percentage from 2010 Schedule A, Part III, line 17 .............

19a

33 1/3% support tests—2011. If the organization did not check the box on line 14, and line 15 is more than 33 1/3% and line 17 is not more than 33 1/3%, check this box and stop here. The organization qualifies as a publicly supported organization .......... right arrow

33 1/3% support tests—2010. If the organization did not check a box on line 14 or line 19a, and line 16 is more than 33 1/3% and line 18 is not more than 33 1/3%, check this box and stop here. The organization qualifies as a publicly supported organization .... right arrow

Private Foundation If the organization did not check a box on line 14, 19a or 19b, check this box and see instructions ..... right arrow

Schedule A (Form 990 or 990-EZ) 2011

Page 4

Part IV

Supplemental Information. Supplemental Information. Complete this part to provide the explanation required by Part II, line 10; Part II, line 17a or 17b; or Part III, line 12. Also complete this part for any additional information. (See instructions).

Facts And Circumstances Test

Explanation

Schedule A (Form 990 or 990-EZ) 2011

Additional Data

Software ID:
Software Version:

- TIN:

Schedule B
(Form 990, 990-EZ,
or 990-PF)

Department of the Treasury
Internal Revenue Service

Schedule of Contributors

Attach to Form 990, 990-EZ, or 990-PF.

OMB No. 1545-0047

2011

Name of organization

STOWERS INSTITUTE FOR MEDICAL RESEARCH

Employer identification number

20-2993509

Organization type (check one):

Filers of:

Section:

Form 990 or 990-EZ

501(c)( ) (enter number) organization

4947(a)(1) nonexempt charitable trust not treated as a private foundation

527 political organization

Form 990-PF

501(c)(3) exempt private foundation

4947(a)(1) nonexempt charitable trust treated as a private foundation

501(c)(3) taxable private foundation

Check if your organization is covered by the General Rule or a Special Rule.
Note. Only a section 501(c)(7), (8), or (10) organization can check boxes for both the General Rule and a Special Rule. See instructions.

General Rule

For an organization filing Form 990, 990-EZ, or 990-PF that received, during the year, $5,000 or more (in money or
property) from any one contributor. Complete Parts I and II.

Special Rules

For a section 501(c)(3) organization filing Form 990 or 990-EZ that met the 33¹/3% support test of the regulations
under sections 509(a)(1) and 170(b)(1)(A)(vi), and received from any one contributor, during the year, a contribution of the
greater of (1) $5,000 or (2) 2% of the amount on (i) Form 990, Part VIII, line 1h, or (ii) Form 990-EZ, line 1. Complete Parts I and II.

For a section 501(c)(7), (8), or (10) organization filing Form 990, or 990-EZ that received from any one contributor,
during the year, total contributions of more than $1,000 for use exclusively for religious, charitable,
scientific, literary, or educational purposes, or the prevention of cruelty to children or animals. Complete Parts I, II, and
III.

For a section 501(c)(7), (8), or (10) organization filing Form 990, or 990-EZ that received from any one contributor,
during the year, contributions for use exclusively for religious, charitable, etc., purposes, but these contributions did
not total to more than $1,000. If this box is checked, enter here the total contributions that were received during
the year for an exclusively religious, charitable, etc., purpose. Do not complete any of the parts unless the General Rule
applies to this organization because it received nonexclusively religious, charitable, etc., contributions of $5,000 or more
during the year. ......................... Arrow Bullet

Caution. An Organization that is not covered by the General Rule and/or the Special Rules does not file Schedule B (Form 990,
990-EZ, or 990-PF), but it must answer “No” on Part IV, line 2, of its Form 990; or check the box on line H of its
Form 990-EZ or on Part I, line 2, of its Form 990-PF, to certify that it does not meet the filing requirements of Schedule B (Form 990,
990-EZ, or 990-PF).

For Paperwork Reduction Act Notice, see the Instructions
for Form 990, 990-EZ, or 990-PF.

Cat. No. 30613XSchedule B (Form 990, 990-EZ, or 990-PF) (2011)

Page 2

Name of organization STOWERS INSTITUTE FOR MEDICAL RESEARCH
Schedule B (Form 990, 990-EZ, or 990-PF) (2011)
Part I	Contributors (see Instructions). Use duplicate copies of Part I if additional space is needed.
(a) No.	(b) Name, address, and ZIP + 4	(c) Total contributions	(d) Type of contribution
RESTRICTED	RESTRICTED RESTRICTED RESTRICTED RESTRICTED, RESTRICTED RESTRICTED	$RESTRICTED	Person Payroll Noncash (Complete Part II if there is a noncash contribution.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Total contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II if there is a noncash contribution.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Total contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II if there is a noncash contribution.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Total contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II if there is a noncash contribution.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Total contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II if there is a noncash contribution.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Total contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II if there is a noncash contribution.)
Schedule B (Form 990, 990-EZ, or 990-PF) (2011)

Page 3

Name of organization STOWERS INSTITUTE FOR MEDICAL RESEARCH
Schedule B (Form 990, 990-EZ, or 990-PF) (2011)
Part II	Noncash Property (see Instructions). Use duplicate copies of Part II if additional space is needed.
(a) No. from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (see instructions).	(d) Date received
		$
(a) No. from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (see instructions).	(d) Date received
		$
(a) No. from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (see instructions).	(d) Date received
		$
(a) No. from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (see instructions).	(d) Date received
		$
(a) No. from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (see instructions).	(d) Date received
		$
(a) No. from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (see instructions).	(d) Date received
		$
Schedule B (Form 990, 990-EZ, or 990-PF) (2011)

Page 4

Schedule B (Form 990, 990-EZ, or 990-PF) (2011)

Name of organization
STOWERS INSTITUTE FOR MEDICAL RESEARCH

Employer identification number

20-2993509

Part III

Exclusively religious, charitable, etc., individual contributions to section 501(c)(7), (8), or (10) organizations
that total more than $1,000 for the year. Complete columns (a) through (e) and the following line entry.
For organizations completing Part III, enter the total of exclusively religious, charitable, etc.,
contributions of $1,000 or less for the year. (Enter this information once. See instructions.) Arrow Bullet

$
Use duplicate copies of Part III if additional space is needed

(a) No.
from
Part I

(b)
Purpose of gift

(d)
Description of how gift is held

(e) Transfer of gift
Transferee's name, address, and ZIP 4	Relationship of transferor to transferee

(a) No.
from
Part I

(b)
Purpose of gift

(d)
Description of how gift is held

(e) Transfer of gift
Transferee's name, address, and ZIP 4	Relationship of transferor to transferee

(a) No.
from
Part I

(b)
Purpose of gift

(d)
Description of how gift is held

(e) Transfer of gift
Transferee's name, address, and ZIP 4	Relationship of transferor to transferee

(a) No.
from
Part I

(b)
Purpose of gift

(d)
Description of how gift is held

(e) Transfer of gift
Transferee's name, address, and ZIP 4	Relationship of transferor to transferee

Schedule B (Form 990, 990-EZ, or 990-PF) (2011)

Additional Data

Software ID:
Software Version:

- TIN:

SCHEDULE D
(Form 990)

Department of the Treasury
Internal Revenue Service

Supplemental Financial Statements

Complete if the organization answered "Yes," to Form 990,
Part IV, line 6, 7, 8, 9, 10, 11a, 11b, 11c, 11d, 11e, 11f, 12a, or 12b
SchDMd Bullet

Attach to Form 990. SchDMd Bullet

See separate instructions.

OMB No. 1545-0047

2011

Open to Public Inspection

Name of the organization

STOWERS INSTITUTE FOR MEDICAL RESEARCH

Employer identification number

20-2993509

Part I

Organizations Maintaining Donor Advised Funds or Other Similar Funds or Accounts. Complete if the organization answered "Yes" to Form 990, Part IV, line 6.

		(a) Donor advised funds	(b) Funds and other accounts
1	Total number at end of year .......
2	Aggregate contributions to (during year) ...
3	Aggregate grants from (during year) ...
4	Aggregate value at end of year .......

Did the organization inform all donors and donor advisors in writing that the assets held in donor advised
funds are the organization's property, subject to the organization's exclusive legal control? ............

Yes No

Did the organization inform all grantees, donors, and donor advisors in writing that grant funds can be
used only for charitable purposes and not for the benefit of the donor or donor advisor, or for any other purpose conferring impermissible private benefit? ...................................

Yes No

Part II

Conservation Easements. Complete if the organization answered "Yes" to Form 990, Part IV, line 7.

Purpose(s) of conservation easements held by the organization (check all that apply).

Preservation of land for public use (e.g., recreation or education) Preservation of an historically important land area

Protection of natural habitat Preservation of a certified historic structure

Preservation of open space

Complete lines 2a through 2d if the organization held a qualified conservation contribution in the form of a conservation easement on the last day of the tax year.


a	Total number of conservation easements .......................	2a
b	Total acreage restricted by conservation easements ..................	2b
c	Number of conservation easements on a certified historic structure included in (a) .....	2c
d	Number of conservation easements included in (c) acquired after 8/17/06, and not on a historic structure listed in the National Register ....................	2d

Number of conservation easements modified, transferred, released, extinguished, or terminated by the organization during
the tax year SchDMd Bullet

Number of states where property subject to conservation easement is located SchDMd Bullet

Does the organization have a written policy regarding the periodic monitoring, inspection, handling of violations, and
enforcement of the conservation easements it holds? .............................

Yes No

Staff and volunteer hours devoted to monitoring, inspecting and enforcing conservation easements during the year SchDMd Bullet

Amount of expenses incurred in monitoring, inspecting, and enforcing conservation easements during the year
SchDMd Bullet

Does each conservation easement reported on line 2(d) above satisfy the requirements of section
170(h)(4)(B)(i) and 170(h)(4)(B)(ii)? ....................................

Yes No

In Part XIV, describe how the organization reports conservation easements in its revenue and expense statement, and
balance sheet, and include, if applicable, the text of the footnote to the organization’s financial statements that describes
the organization’s accounting for conservation easements.

Part III

Organizations Maintaining Collections of Art, Historical Treasures, or Other Similar Assets.
Complete if the organization answered "Yes" to Form 990, Part IV, line 8.

If the organization elected, as permitted under SFAS 116 (ASC 958), not to report in its revenue statement and balance sheet works of
art, historical treasures, or other similar assets held for public exhibition, education or research in furtherance of public service,
provide, in Part XIV, the text of the footnote to its financial statements that describes these items.

If the organization elected, as permitted under SFAS 116 (ASC 958), to report in its revenue statement and balance sheet works of art,
historical treasures, or other similar assets held for public exhibition, education, or research in furtherance of public service,
provide the following amounts relating to these items:

(i)

Revenues included in Form 990, Part VIII, line 1 ........................ SchDMd Bullet

(ii)

Assets included in Form 990, Part X .............................. SchDMd Bullet

If the organization received or held works of art, historical treasures, or other similar assets for financial gain, provide the
following amounts required to be reported under SFAS 116 (ASC 958), relating to these items:

Revenues included in Form 990, Part VIII, line 1 .......................... SchDMd Bullet

Assets included in Form 990, Part X ............................... SchDMd Bullet

For Privacy Act and Paperwork Reduction Act Notice, see the Intructions for Form 990

Cat. No. 52283D

Schedule D (Form 990) 2011

Page 2

Part III

Organizations Maintaining Collections of Art, Historical Treasures, or Other Similar Assets (continued)

Using the organization’s accession and other records, check any of the following that are a significant use of its collection
items (check all that apply):

Public exhibition

Loan or exchange programs

Scholarly research

Other

Preservation for future generations

Provide a description of the organization’s collections and explain how they further the organization’s exempt purpose in
Part XIV.

During the year, did the organization solicit or receive donations of art, historical treasures or other similar
assets to be sold to raise funds rather than to be maintained as part of the organization’s collection?........

Yes No

Part IV

Escrow and Custodial Arrangements. Complete if the organization answered "Yes" to Form 990,
Part IV, line 9, or reported an amount on Form 990, Part X, line 21.

Is the organization an agent, trustee, custodian or other intermediary for contributions or other assets not
included on Form 990, Part X? ....................................

Yes No

If "Yes," explain the arrangement in Part XIV and complete the following table:


c	Beginning balance .................................	1c
d	Additions during the year ..............................	1d
e	Distributions during the year .............................	1e
f	Ending balance ...................................	1f

Did the organization include an amount on Form 990, Part X, line 21? .....................

Yes No

If “Yes,” explain the arrangement in Part XIV.

Part V

Endowment Funds. Complete if the organization answered "Yes" to Form 990, Part IV, line 10.

		(a)Current Year	(b)Prior Year	(c)Two Years Back	(d)Three Years Back	(e)Four Years Back
1a	Beginning of year balance ....
b	Contributions ........
c	Net investment earnings, gains, and losses ...
d	Grants or scholarships .....
e	Other expenditures for facilities and programs ........
f	Administrative expenses ....
g	End of year balance ......

Provide the estimated percentage of the year end balance (line 1g) held as:

Board designated or quasi-endowment SchDMd Bullet

Permanent endowment SchDMd Bullet

Temporarily restricted endowment SchDMd Bullet

The percentages in lines 2a, 2b, and 2c should equal 100%.

Are there endowment funds not in the possession of the organization that are held and administered for the
organization by:

Yes

(i) unrelated organizations ........................

3a(i)

(ii) related organizations ........................

3a(ii)

If "Yes" to 3a(ii), are the related organizations listed as required on Schedule R? .........

Describe in Part XIV the intended uses of the organization's endowment funds.

Part VI

Land, Buildings, and Equipment. See Form 990, Part X, line 10.

Description of property		(b)Cost or other basis (other)	(c) Accumulated depreciation	(d) Book value
1a	Land .................	3,400,000		3,400,000
b	Buildings ................	224,028,188	65,254,547	158,773,641
c	Leasehold improvements ............
d	Equipment ................	86,377,682	66,209,254	20,168,428
e	Other .................	6,300		6,300
Total. Add lines 1a through 1e. (Column (d) must equal Form 990, Part X, column (B), line 10(c).).......				182,348,369

Schedule D (Form 990) 2011

Page 3

Part VII

InvestmentsOther Securities. See Form 990, Part X, line 12.

(a) Description of security or category (including name of security)		(b)Book value	(c) Method of valuation: Cost or end-of-year market value
(1)Financial derivatives
(2)Closely-held equity interests
Other








Total. (Column (b) must equal Form 990, Part X, col. (B) line 12.)

Part VIII

InvestmentsProgram Related. See Form 990, Part X, line 13.

(a) Description of investment type		(b) Book value	(c) Method of valuation: Cost or end-of-year market value









Total. (Column (b) must equal Form 990, Part X, col.(B) line 13.)

Part IX

Other Assets. See Form 990, Part X, line 15.

(a) Description				(b) Book value
(1) ANNUITY RECEIVABLE				202,347,168
(2) OTHER RECEIVABLES				575,427







Total. (Column (b) must equal Form 990, Part X, col.(B) line 15.)...........				202,922,595

Part X

Other Liabilities. See Form 990, Part X, line 25.

1.(a) Description of Liability		(b) Book value
Federal Income Taxes		0
ADVANCES FROM AFFILIATES		4,394,500
ANNUITY PAYABLE		197,132,283
ROYALTIES PAYABLE		173,624






Total. (Column (b) must equal Form 990, Part X, col.(B) line 25.)		201,700,407
2. Fin 48 (ASC 740) Footnote. In Part XIV, provide the text of the footnote to the organization's financial statements that reports the organization's liability for uncertain tax positions under FIN 48 (ASC740).

Schedule D (Form 990) 2011

Page 4

Part XI Reconciliation of Change in Net Assets from Form 990 to Financial Statements
1	Total revenue (Form 990, Part VIII, column (A), line 12) ....................	1
2	Total expenses (Form 990, Part IX, column (A), line 25) .....................	2
3	Excess or (deficit) for the year. Subtract line 2 from line 1 .............	3
4	Net unrealized gains (losses) on investments ..........................	4
5	Donated services and use of facilities .............................	5
6	Investment expenses ...................................	6
7	Prior period adjustments ..................................	7
8	Other (Describe in Part XIV.) .................................	8
9	Total adjustments (net). Add lines 4 through 8 .........................	9
10	Excess or (deficit) for the year per financial statements. Combine lines 3 and 9 .........	10

Part XII Reconciliation of Revenue per Audited Financial Statements With Revenue per Return
1	Total revenue, gains, and other support per audited financial statements .......		1
2	Amounts included on line 1 but not on Form 990, Part VIII, line 12:
a	Net unrealized gains on investments ..........	2a
b	Donated services and use of facilities .........	2b
c	Recoveries of prior year grants ...........	2c
d	Other (Describe in Part XIV.) ............	2d
e	Add lines 2a through 2d .....................		2e
3	Subtract line 2e from line 1.....................		3
4	Amounts included on Form 990, Part VIII, line 12, but not on line 1:
a	Investment expenses not included on Form 990, Part VIII, line 7b .	4a
b	Other (Describe in Part XIV.) ...........	4b
c	Add lines 4a and 4b.......................		4c
5	Total Revenue. Add lines 3 and 4c. (This must equal Form 990, Part I, line 12.) ......		5

Part XIII Reconciliation of Expenses per Audited Financial Statements With Expenses per Return
1	Total expenses and losses per audited financial statements .............		1
2	Amounts included on line 1 but not on Form 990, Part IX, line 25:
a	Donated services and use of facilities ..........	2a
b	Prior year adjustments ..............	2b
c	Other losses ................	2c
d	Other (Describe in Part XIV.) ............	2d
e	Add lines 2a through 2d......................		2e
3	Subtract line 2e from line 1.....................		3
4	Amounts included on Form 990, Part IX, line 25, but not on line 1:
a	Investment expenses not included on Form 990, Part VIII, line 7b ..	4a
b	Other (Describe in Part XIV.) ............	4b
c	Add lines 4a and 4b.......................		4c
5	Total expenses. Add lines 3 and 4c. (This must equal Form 990, Part I, line 18.) ......		5

Part XIV

Supplemental Information

Complete this part to provide the descriptions required for Part II, lines 3, 5, and 9; Part III, lines 1a and 4; Part lV, lines 1b and 2b;
Part V, line 4; Part X; Part XI, line 8; Part XII, lines 2d and 4b; and Part XIII, lines 2d and 4b. Also complete this part to provide any additional information.

Identifier	Return Reference	Explanation
SCHEDULE D	PART X, LINE 2	FIN 48 FINANCIAL STATEMENT FOOTNOTE FROM THE CONSOLIDATED STATEMENTS OF STOWERS INSTITUTE FOR MEDICAL RESEARCH (THE INSTITUTE) IS AS FOLLOWS: THE INSTITUTE RECOGNIZES THE EFFECT OF INCOME TAX POSITIONS ONLY IF THOSE POSITIONS ARE MORE LIKELY THAN NOT OF BEING SUSTAINED. RECOGNIZED INCOME TAX POSITIONS ARE MEASURED AT THE LARGEST AMOUNT THAT IS GREATER THAN 50% LIKELY OF BEING REALIZED. AS DESCRIBED ABOVE IN NOTE 1, THE INSTITUTE CONSISTS OF FIVE TAX-EXEMPT ENTITIES AS DESCRIBED IN SECTION 501(C)(3) OF THE CODE. THEREORE, IT IS THE INSITUTE'S TAX POSITION THAT THESE FIVE ENTITIES ARE EXEMPT FROM FEDERAL INCOME TAXES.

Schedule D (Form 990) 2011

Additional Data

Software ID:
Software Version:

- TIN:

Schedule I
(Form 990)

Department of the Treasury
Internal Revenue Service

Grants and Other Assistance to Organizations,
Governments and Individuals in the United States

Complete if the organization answered "Yes," to Form 990, Part IV, line 21 or 22.
lBullet

Attach to Form 990

OMB No. 1545-0047

2011

Open to Public
Inspection

Name of the organization
STOWERS INSTITUTE FOR MEDICAL RESEARCH

Employer identification number
20-2993509

Part I

General Information on Grants and Assistance

Does the organization maintain records to substantiate the amount of the grants or assistance, the grantees' eligibility for the grants or assistance, and
the selection criteria used to award the grants or assistance? ....................................

Yes No

Describe in Part IV the organization's procedures for monitoring the use of grant funds in the United States.

Part II

Grants and Other Assistance to Governments and Organizations in the United States. Complete if the organization answered "Yes" to
Form 990, Part IV, line 21 for any recipient that received more than $5,000. Check this box if no one recipient received more than $5,000. Use
Part IV and Schedule I-1 (Form 990) if additional space is needed ......................... lBullet

(a) Name and address of organization or government	(b) EIN	(c) IRC Code section if applicable	(d) Amount of cash grant	(e) Amount of non-cash assistance	(f) Method of valuation (book, FMV, appraisal, other)	(g) Description of non-cash assistance	(h) Purpose of grant or assistance

Enter total number of section 501(c)(3) and government organizations listed in the line 1 table ................. Bullet Image

Enter total number of other organizations listed in the line 1 table ......................... . Bullet Image

For Privacy Act and Paperwork Reduction Act Notice, see the Instructions for Form 990.

Cat. No. 50055P

Schedule I (Form 990) 2011

Page 2

Part III

Grants and Other Assistance to Individuals in the United States. Complete if the organization answered "Yes" to Form 990, Part IV, line 22.
Use Schedule I-1 (Form 990) if additional space is needed.

(a)Type of grant or assistance	(b)Number of recipients	(c)Amount of cash grant	(e)Method of valuation (book, FMV, appraisal, other)	(f)Description of non-cash assistance
(1) STIPENDS/FELLOWSHIPS	64	1,151,122	N/A	N/A

Part IV

Supplemental Information. Complete this part to provide the information required in Part I, line 2, and any other additional information.

Identifier	Return Reference	Explanation
SCHEDULE I	PART I, LINE 2	SIMR PROVIDES TRAINING STIPEND/FELLOWSHIPS TO UNDERGRADUATES, GRADUATES, AND POST-DOCTORAL CANDIDATES. THESE STIPENDS/FELLOWSHIPS ARE PROVIDED FOR THE INDIVIDUAL'S TRAINING AND NOT AS COMPENSATION FOR ANY SERVICES PROVIDED BY THEM TO SIMR. STIPENDS/FELLOWSHIPS ARE OFFERED ON A NON-DISCRIMINATORY BASIS TO INDIVIDUALS STUDYING A BASIC BIOMEDICAL FIELD WITH THE OBJECTIVE OF CONTINUING IN THIS FIELD UPON THE COMPLETION OF THEIR EDUCATION AND TRAINING.

Schedule I (Form 990) 2011

Additional Data

Software ID:
Software Version:

- TIN:

Schedule J
(Form 990)

Department of the Treasury
Internal Revenue Service

Compensation Information

For certain Officers, Directors, Trustees, Key Employees, and Highest
Compensated Employees
SchJMediumBullet

Complete if the organization answered "Yes" to Form 990,
Part IV, question 23.
SchJMediumBullet

Attach to Form 990. SchJMediumBullet

See separate instructions.

OMB No. 1545-0047

2011

Open to Public Inspection

Name of the organization

STOWERS INSTITUTE FOR MEDICAL RESEARCH

Employer identification number

20-2993509

Part I

Questions Regarding Compensation

Yes

Check the appropiate box(es) if the organization provided any of the following to or for a person listed in Form
990, Part VII, Section A, line 1a. Complete Part III to provide any relevant information regarding these items.

First-class or charter travel Housing allowance or residence for personal use

Travel for companions Payments for business use of personal residence

Tax idemnification and gross-up payments Health or social club dues or initiation fees

Discretionary spending account Personal services (e.g., maid, chauffeur, chef)

If any of the boxes in line 1a are checked, did the organization follow a written policy regarding payment or reimbursement or provision of all the expenses described above? If "No," complete Part III to explain....

Yes

Did the organization require substantiation prior to reimbursing or allowing expenses incurred by all
officers, directors, trustees, and the CEO/Executive Director, regarding the items checked in line 1a? ....

Yes

Indicate which, if any, of the following the organization uses to establish the compensation of the
organization's CEO/Executive Director. Check all that apply. Do not check any boxes for methods
used by a related organization to establish compensation of the CEO/Executive Director, but explain in Part III.

Compensation committee Written employment contract

Independent compensation consultant Compensation survey or study

Form 990 of other organizations Approval by the board or compensation committee

During the year, did any person listed in Form 990, Part VII, Section A, line 1a with respect to the filing organization or a related organization:

Receive a severance payment or change-of-control payment? ...............

Participate in, or receive payment from, a supplemental nonqualified retirement plan? ........

Participate in, or receive payment from, an equity-based compensation arrangement? ........

If "Yes" to any of lines 4a-c, list the persons and provide the applicable amounts for each item in Part III.

Only 501(c)(3) and 501(c)(4) organizations only must complete lines 5-9.

For persons listed in form 990, Part VII, Section A, line 1a, did the organization pay or accrue any
compensation contingent on the revenues of:

The organization? ...........................

Yes

Any related organization? .........................

If "Yes," to line 5a or 5b, describe in Part III.

For persons listed in form 990, Part VII, Section A, line 1a, did the organization pay or accrue any
compensation contingent on the net earnings of:

The organization? ...........................

Any related organization? .........................

If "Yes," to line 6a or 6b, describe in Part III.

For persons listed in Form 990, Part VII, Section A, line 1a, did the organization provide any non-fixed
payments not described in lines 5 and 6? If "Yes," describe in Part III ............

Were any amounts reported in Form 990, Part VII, paid or accured pursuant to a contract that was
subject to the initial contract exception described in Regulations section 53.4958-4(a)(3)? If "Yes," describe
in Part III .............................

If "Yes" to line 8, did the organization also follow the rebuttable presumption procedure described in Regulations section 53.4958-6(c)? .........................

For Privacy Act and Paperwork Reduction Act Notice, see the Intructions for Form 990

Cat. No. 50053T

Schedule J (Form 990) 2011

Page 2

Part II

Officers, Directors, Trustees, Key Employees, and Highest Compensated Employees. Use duplicate copies if additional space is needed.

For each individual whose compensation must be reported in Schedule J, report compensation from the organization on row (i) and from related organizations, described in the
instructions on row (ii). Do not list any individuals that are not listed on Form 990, Part VII.

Note. The sum of columns (B)(i)-(iii) for each listed individual must equal the total amount of Form 990, Part VII, Section A, line 1a, applicable column (D) and column (E) for that individual.

(A) Name		(B) Breakdown of W-2 and/or 1099-MISC compensation			(C) Retirement and other deferred compensation	(D) Nontaxable benefits	(E) Total of columns (B)(i)-(D)	(F) Compensation reported as deferred in prior Form 990
(A) Name		(i) Base compensation	(ii) Bonus & incentive compensation	(iii) Other reportable compensation	(C) Retirement and other deferred compensation	(D) Nontaxable benefits	(E) Total of columns (B)(i)-(D)	(F) Compensation reported as deferred in prior Form 990
(1) DAVID A WELTE	(i) (ii)	0 947,816	0 0	0 29,301	0 36,750	0 18,547	0 1,032,414	0 0
(2) RODERICK L STURGEON	(i) (ii)	0 1,114,083	0 0	0 43,776	0 36,750	0 15,212	0 1,209,821	0 0
(3) WILLIAM B NEAVES	(i) (ii)	440,014 0	0 0	7,747 0	36,750 0	12,352 0	496,863 0	0 0
(4) DAVID M CHAO	(i) (ii)	1,140,406 0	0 0	2,340 0	36,750 0	1,420 0	1,180,916 0	0 0
(5) ROBERT E KRUMLAUF	(i) (ii)	445,902 0	0 0	3,437 0	36,750 0	14,799 0	500,888 0	0 0
(6) RONALD C CONAWAY	(i) (ii)	249,609 0	0 0	2,196 0	36,750 0	1,419 0	289,974 0	0 0
(7) JOAN W CONAWAY	(i) (ii)	247,456 0	0 0	2,196 0	36,750 0	12,802 0	299,204 0	0 0
(8) JERRY L WORKMAN	(i) (ii)	248,936 0	0 0	1,195 0	36,750 0	7,160 0	294,041 0	0 0
(9) R SCOTT HAWLEY	(i) (ii)	268,174 0	0 0	2,233 0	36,750 0	20,140 0	327,297 0	0 0
(10) ALI SHILATIFARD	(i) (ii)	225,029 0	0 0	16,738 0	34,388 0	18,082 0	294,237 0	0 0
(11) RICHARD W BROWN	(i) (ii)	0 1,702,671	0 0	0 29,969	0 36,750	0 11,512	0 1,780,902	0 0

Schedule J (Form 990) 2011

Page 3

Part III

Supplemental Information

Complete this part to provide the information, explanation, or descriptions required for Part I, lines 1a, 1b, 3, 4c, 5a, 5b, 6a, 6b, 7, and 8. Also complete this part for any additional information.

Identifier	Return Reference	Explanation
PART I, LINE 1A:		SIMR HAS WRITTEN EMPLOYMENT CONTRACTS WITH WILLIAM B. NEAVES, PRESIDENT EMERITUS, AND DAVID M. CHAO, PRESIDENT, WHICH PROVIDES FOR TAXABLE TERM LIFE BENEFITS AND FOR THE EXECUTIVES TO RECEIVE TAX GROSS-UP PAYMENTS SUFFICIENT TO COVER THE TAXES ON THE BENEFITS.
PART I, LINE 1B:		SIMR PROVIDED THE BENEFITS DESCRIBED IN RESPONSE TO LINE 1A PURSUANT TO WRITTEN EMPLOYMENT CONTRACTS THAT WERE APPROVED BY SIMR'S GOVERNING BOARD. SEE RESPONSE TO FORM 990, PART VI, SECTION B, LINE 15, FOR ADDITIONAL PROCESSES RELATED TO DETERMINING EXECUTIVE COMPENSATION.
PART I, LINE 5A:		SIMR ACCRUED A PAYMENT OF $86,812 DUE TO ROBERT E. KRUMLAUF, SCIENTIFIC DIRECTOR. THIS PAYMENT REPRESENTS THE PORTION OF THE NET ROYALTIES RECEIVED BY SIMR FOR LICENSED SCIENTIFIC DISCOVERY TECHNOLOGY THAT IS PAYABLE TO ROBERT E. KRUMLAUF, PH.D., FOR HIS PARTICIPATION IN THE DISCOVERY.

Schedule J (Form 990) 2011

Additional Data

Software ID:
Software Version:

- TIN:

Schedule L
(Form 990 or 990-EZ)

Department of the Treasury
Internal Revenue Service

Transactions with Interested Persons

Complete if the organization answered
"Yes" on Form 990, Part IV, lines 25a, 25b, 26, 27, 28a, 28b, or 28c,
or Form 990-EZ, Part V lines 38a or 40b.
MediumBullet

Attach to Form 990 or Form 990-EZ. MediumBullet

See separate instructions.

OMB No. 1545-0047

2011

Open to Public Inspection

Name of the organization

STOWERS INSTITUTE FOR MEDICAL RESEARCH

Employer identification number

20-2993509

Part I

Excess Benefit Transactions (section 501(c)(3) and section 501 (c)(4) organizations only).
Complete if the organization answered "Yes" on Form 990, Part IV, line 25a or 25b, or Form 990-EZ, Part V, line 40b.

1(a) Name of disqualified person	(b) Description of transaction	(c) Corrected?
1(a) Name of disqualified person	(b) Description of transaction	Yes	No

Enter the amount of tax imposed on the organization managers or disqualified persons during the year under section 4958. ......................... Bullet Image

Enter the amount of tax, if any, on line 2, above, reimbursed by the organization ....... Bullet Image

Part II

Loans to and/or From Interested Persons.
Complete if the organization answered "Yes" on Form 990, Part IV, line 26, or Form 990-EZ, Part V, line 38a.

(a) Name of interested person and purpose	(b) Loan to or from the organization?		(c)Original principal amount	(d)Balance due	(e) In default?		(f) Approved by board or committee?		(g)Written agreement?
(a) Name of interested person and purpose	To	From	(c)Original principal amount	(d)Balance due	Yes	No	Yes	No	Yes	No






Total ............... $

Part III

Grants or Assistance Benefitting Interested Persons.
Complete if the organization answered "Yes" on Form 990, Part IV, line 27.

(a) Name of interested person	(b)Relationship between interested person and the organization	(c)Amount of grant or type of assistance

For Privacy Act and Paperwork Reduction Act Notice, see the
Instructions for Form 990 or 990-EZ.

Cat. No. 50056A

Schedule L (Form 990 or 990-EZ) 2011

Page 2

Part IV

Business Transactions Involving Interested Persons.
Complete if the organization answered "Yes" on Form 990, Part IV, line 28a, 28b, or 28c.

(a) Name of interested person	(b) Relationship between interested person and the organization	(c) Amount of transaction	(d) Description of transaction	(e) Sharing of organization's revenues?
(a) Name of interested person		(c) Amount of transaction	(d) Description of transaction	Yes	No
(1) AMERICAN CENTURY COMPANIES INC	SEE PART V	500,000	SEE PART V		No
(2) JULIA ZEITLINGER PhD	SEE PART V	109,137	EMPLOYEE OF SIMR		No
(3) LEANNE WIEDEMANN PhD	SEE PART V	182,777	EMPLOYEE OF SIMR		No

Part V

Supplemental Information

Complete this part to provide additional information for responses to questions on Schedule L (see instructions).

Identifier	Return Reference	Explanation
PART IV, LINE (1):		RICHARD W. BROWN, DAVID A. WELTE, AND RODERICK L. STURGEON ARE CURRENT DIRECTORS OF SIMR AND ALSO DIRECTORS OF AMERICAN CENTURY COMPANIES, INC. ("ACCI"). JAMES E. STOWERS JR., A DIRECTOR OF SIMR, IS ALSO THE FOUNDER OF ACCI. SIMR, ALONG WITH MR. STOWERS, OTHER STOWERS FAMILY MEMBERS, AND OTHER RELATED PARTIES DISCLOSED IN SCHEDULE R RETAIN A CONTROLLING VOTING INTEREST IN ACCI. SIMR RECEIVES INVESTMENT MANAGEMENT SERVICES FROM AMERICAN CENTURY INVESTMENTS ("ACI"). SIMR PAYS THE SAME ADMINISTRATIVE FEES FOR THESE SERVICES AS ANY ARMS-LENGTH MUTUAL FUND INVESTOR. THE VALUE OF THESE SERVICES, ESTIMATED BY MULTIPLYING SIMR'S AVERAGE AMOUNT OF MUTUAL FUND HOLDINGS THROUGHOUT THE YEAR BY THE PUBLISHED ADMINISTRATIVE FEE PERCENTAGE FOR THE APPLICABLE FUNDS, WAS APPROXIMATELY $500,000. IN SELECTING ACI TO MANAGE ITS LIQUID INVESTMENTS, SIMR SELECTED A HIGH QUALITY MUTUAL FUND COMPANY WITH AN OUTSTANDING TRACK RECORD.
PART IV, LINE (2) & (3):		JULIA ZEITLINGER, PH.D, IS THE SPOUSE OF DAVID M. CHAO, PRESIDENT OF SIMR. MS. ZEITLINGER IS AN ASSISTANT INVESTIGATOR AT SIMR. MS. ZEITLINGER'S PREVIOUS EMPLOYMENT BEFORE SIMR WAS WITH THE WHITEHEAD INSTITUTE FOR MEDICAL RESEARCH WHERE SHE WAS THE RECIPIENT OF A POSTDOCTORAL FELLOWSHIP FROM THE HUMAN FRONTIER SCIENCE PROGRAM. LEANNE WIEDMANN, PH.D, IS THE SPOUSE OF ROBERT KRUMLAUGF, SCIENTIFIC DIRECTOR OF SIMR. MS. WIEDEMANN PERFORMS INDEPENDENT SCIENCE RESEARCH AT SIMR AND IS CONCURRENTLY A PROFESSOR AT THE UNIVERSITY OF KANSAS MEDICAL CENTER IN THE DEPARTMENT OF PATHOLOGY AND LABORATORY MEDICINE.

Schedule L (Form 990 or 990-EZ) 2011

Additional Data

Software ID:
Software Version:

- TIN:

SCHEDULE M
(Form 990)

Department of the Treasury

Internal Revenue Service

NonCash Contributions

Complete if the organization answered "Yes" on Form 990, Part IV, lines 29 or 30.
Right pointing arrow large image

Attach to Form 990.

OMB No. 1545-0047

2011

Open to Public Inspection

Name of the organization

STOWERS INSTITUTE FOR MEDICAL RESEARCH

Employer identification number

20-2993509

Part I

Types of Property

	(a) Check if applicable	(b) Number of Contributions or items contributed	(c) Noncash contribution amounts reported on Form 990, Part VIII, line 1g	(d) Method of determining noncash contribution amounts
1 Art—Works of art ....
2 Art—Historical treasures .
3 Art—Fractional interests ..
4 Books and publications ..
5 Clothing and household goods .......
6 Cars and other vehicles ..
7 Boats and planes ....
8 Intellectual property ...
9 Securities—Publicly traded .	X	2	49,563,919	FAIR MARKET VALUE
10 Securities—Closely held stock .	X	1	337,691	FAIR MARKET VALUE
11 Securities—Partnership, LLC, or trust interests ....
12 Securities—Miscellaneous ..
13 Qualified conservation contribution—Historic structures .....
14 Qualified conservation contribution—Other ...
15 Real estate—Residential .
16 Real estate—Commercial ..
17 Real estate—Other ...
18 Collectibles .....
19 Food inventory ...
20 Drugs and medical supplies .
21 Taxidermy ......
22 Historical artifacts ....
23 Scientific specimens ..
24 Archeological artifacts ...
25 Other ( SUPPLIES )	X	1	5,018	FAIR MARKET VALUE
26 Other ( )
27 Other ( )
28 Other ( )

Number of Forms 8283 received by the organization during the tax year for contributions
for which the organization completed Form 8283, Part IV, Donee Acknowledgement ...

Yes

30a

During the year, did the organization receive by contribution any property reported in Part I, lines 1-28 that it

must hold for at least three years from the date of the initial contribution, and which is not required to be used

for exempt purposes for the entire holding period? ..................

30a

If "Yes," describe the arrangement in Part II.

Does the organization have a gift acceptance policy that requires the review of any non-standard contributions?

Yes

32a

Does the organization hire or use third parties or related organizations to solicit, process, or sell noncash

contributions? ............................

32a

If "Yes," describe in Part II.

If the organization did not report revenues in column (c) for a type of property for which column (a) is checked,

describe in Part II.

For Privacy Act and Paperwork Reduction Act Notice, see the Instructions for Form 990.

Cat. No. 51227J

Schedule M (Form 990) 2011

Page 2

Part II

Supplemental Information. Complete this part to provide the information required by Part I, lines 30b,
32b, and 33 and whether the organization is reporting in Part I, column (b) the number of contributions, the number of items received, or a combination of both. Also complete this part for any additional information.

Identifier	Return Reference	Explanation
PART I, COLUMN B:		THE AMOUNTS SHOWN IN PART I, COLUMN (B) FOR "NUMBER OF CONTRIBUTIONS" REPRESENTS THE TOTAL NUMBER OF CONTRIBUTORS AND NOT NECESSARILY THE TOTAL NUMBER OF ITEMS CONTRIBUTED.

Schedule M (Form 990) 2011

Additional Data

Software ID:
Software Version:

- TIN:

SCHEDULE O
(Form 990 or 990-EZ)

Department of the Treasury
Internal Revenue Service

Supplemental Information to Form 990 or 990-EZ

Complete to provide information for responses to specific questions on
Form 990 or to provide any additional information.
MediumBullet

Attach to Form 990 or 990-EZ.

OMB No. 1545-0047

2011

Open to Public
Inspection

Name of the organization

STOWERS INSTITUTE FOR MEDICAL RESEARCH

Employer identification number

20-2993509

Identifier	Return Reference	Explanation
FORM 990, PART III, LINE 1:		THE STOWERS INSTITUTE FOR MEDICAL RESEARCH PERFORMS MEDICAL RESEARCH IN THE PUBLIC INTEREST WITH THE GOAL OF EXPANDING OUR UNDERSTANDING OF FUNDAMENTAL PROCESSES IN LIVING CELLS AND IMPROVING LIFE'S QUALITY THROUGH INNOVATIVE APPROACHES TO THE CAUSES, TREATMENT, AND PREVENTION OF DISEASE. FORM 990, PART III, LINE 4: SIMR'S ACCOMPLISHMENTS ARE DESCRIBED AT END OF SCHEDULE O. FORM 990, PART VI, LINE 2: JAMES E. STOWERS JR. AND VIRGINIA G. STOWERS, DIRECTORS OF SIMR, HAVE A FAMILY RELATIONSHIP. RICHARD W. BROWN, DAVID A. WELTE, AND RODERICK L. STURGEON, ALL DIRECTORS OF SIMR, HAVE A BUSINESS RELATIONSHIP; THEY SERVE ON THE BOARD OF AMERICAN CENTURY COMPANIES, INC. ("ACCI") AS DESCRIBED IN RESPONSE TO SCHEDULE L, PART IV. RICHARD W. BROWN, WILLIAM B. NEAVES, DAVID M. CHAO, AND RODERICK L. STURGEON, DIRECTORS OF SIMR, HAVE A BUSINESS RELATIONSHIP; THEY ALL SERVE ON THE BOARD OF BIOMED VALLEY DISCOVERIES, INC., A RELATED PARTY AS DISCUSSED ON SCHEDULE R. FORM 990, PART VI, LINE 11B: THE DATA AND INFORMATION NECESSARY TO PREPARE SIMR'S FORM 990 WAS COMPILED BY SIMR'S ACCOUNTING DEPARTMENT AND THEN REVIEWED BY OUR TAX ATTORNEY AT BRYAN CAVE, LLC. PRICEWATERHOUSECOOPERS ("PWC"), OUR EXTERNAL TAX PREPARERS, USE THIS INFORMATION TO PREPARE THE FORM 990. THE COMPLETED FORM 990, INCLUDING REQUIRED SCHEDULES, IS DISTRIBUTED IN ADVANCE TO ALL OFFICERS OF SIMR FOR THEIR REVIEW AND COMMENTS BEFORE THE FORM 990 IS FILED WITH THE IRS. AFTER THE PREPARATION AND REVIEW PROCESS DESCRIBED ABOVE, THE FORM 990, INCLUDING REQUIRED SCHEDULES, IS PROVIDED TO EACH VOTING MEMBER OF THE ORGANIZATION'S BOARD BEFORE IT IS FILED WITH THE IRS. FORM 990, PART VI, LINE 12C: SIMR HAS ADOPTED A "CONFLICTS OF INTEREST AND DIRECTOR INDEPENDENCE POLICY". EACH DIRECTOR, OFFICER, AND OTHER PERSON WHO IS IN A POSITION TO EXERCISE SUBSTANTIAL INFLUENCE OVER DECISIONS OF SIMR ARE REQUIRED TO ANNUALLY COMPLETE AND SIGN A DISCLOSURE STATEMENT THAT IS PART OF THE POLICY. A COVERED PERSON MUST ALSO DISCLOSE THE EXISTENCE OF A POTENTIAL CONFLICT AND ALL MATERIAL FACTS TO THE GOVERNING BOARD AS SOON AS THE PERSON HAS KNOWLEDGE THAT A POTENTIAL CONFLICT MIGHT EXIST. SIMR CONDUCTS PERIODIC AND ADHOC REVIEWS OF TRANSACTIONS AND AGREEMENTS TO INSURE THAT IT ENGAGES ONLY IN ACTIVITIES THAT ARE CONSISTENT WITH ITS TAX-EXEMPT PURPOSE. FORM 990, PART VI, LINES 15A & 15B: THE PROCESS FOR DETERMINING THE REASONABLENESS OF THE COMPENSATION FOR SIMR'S PRESIDENT AND CEO INCLUDED RETAINING THE SERVICES OF A NATIONALLY KNOWN COMPENSATION CONSULTANT TO PROVIDE DATA AND ANALYSIS TO DETERMINE COMPARABLE SALARY AND BENEFITS FOR SIMILARLY QUALIFIED PERSONS IN COMPARABLE POSTIONS AT SIMILARLY SITUATED ORGANIZATIONS. COMPENSATION WAS DOCUMENTED IN EMPLOYMENT CONTRACTS WHICH WERE APPROVED BY THE GOVERNING BODY AS DOCUMENTED IN THE OFFICIAL MINUTES. THE PROCESS WAS LAST UNDERTAKEN FOR THE PRESIDENT AND CEO POSITIONS IN 2009 AT THE TIME THE CURRENT CONTRACTS IN EFFECT WERE EXECUTED. ALSO, A REVIEW PROCESS FOR ALL SIMR EXECUTIVES WAS COMMENCED IN SPRING 2012. FORM 990, PART VI, LINE 19: SIMR'S GOVERNING DOCUMENTS, CONFLICT OF INTEREST POLICY, AND FINANCIAL STATEMENTS ARE AVAILABLE ON REQUEST.
FORM 990, PART XI, LINE 5:	OTHER CHANGES IN NET ASSETS INCLUDE THE FOLLOWING:	ACTUARIAL LOSS ON ANNUITY (587,951); UNREALIZED LOSSES ON INVESTMENTS (878,152); TOTAL OTHER CHANGES IN NET ASSETS $(1,466,103)
FORM 990, PART III, LINE 4:	2011 PROGRAM SERVICE ACCOMPLISHMENTS	THE STOWERS INSTITUTE FOR MEDICAL RESEARCH ("SIMR") IS A PRIVATE, NONPROFIT MEDICAL RESEARCH ORGANIZATION. SIMR WAS FOUNDED IN 1994 BY JIM AND VIRGINIA STOWERS, TWO CANCER SURVIVORS WHO HAVE DEDICATED THEIR FORTUNE TO SUPPORTING BASIC RESEARCH IN CELL AND MOLECULAR BIOLOGY THAT WILL PROVIDE LONG-TERM SOLUTIONS TO GENE-BASED DISEASES. SIMR CONDUCTS BASIC BIOMEDICAL RESEARCH IN THE PUBLIC INTEREST THAT WILL ULTIMATELY PROVIDE A GREATER UNDERSTANDING OF THE GENES AND PROTEINS THAT CONTROL HOW CELLS IN OUR BODIES MULTIPLY, FORM TISSUES, AND DIE. LIKE A GROWING NUMBER OF SCIENTISTS TODAY, INSTITUTE SCIENTISTS ARE CONVINCED THAT BY STUDYING THE BASIC BIOLOGY OF CELLS THEY WILL DISCOVER HOW GENES CAUSE MANY DISEASES, INCLUDING CANCER, DIABETES, AND DEMENTIA. BASIC RESEARCH CONDUCTED AT SIMR SHOULD POINT THE WAY TO THE DEVELOPMENT OF NEW PREVENTIONS, TREATMENTS, AND CURES FOR GENETIC DISEASES.
FORM 990, PART III, LINE 4 CONT.	2011 NOTABLE RESEARCH RESULTS	IN 2011, SIMR RESEARCH TEAMS MADE DISCOVERIES MERITING PUBLICATION IN LEADING PEER-REVIEWED SCIENTIFIC JOURNALS - 66 ORIGINAL RESEARCH PAPERS IN ALL. SIMR RESEARCH TEAMS ALSO PUBLISHED 44 REVIEWS, COMMENTARIES, CHAPTERS, AND ONE BOOK. SOME OF THE HIGHLIGHTS AMONG PAPERS PUBLISHED IN 2011 INCLUDE: THE ZEITLINGER LAB DISCOVERED THAT THE BINDING OF THE TRANSCRIPTION FACTOR TWIST IS HIGHLY CONSERVED ACROSS SIX DROSOPHILA SPECIES, REVEALING STRONG FUNCTIONAL CONSTRAINTS AT ITS ENHANCERS (PUBLISHED IN THE APRIL 10 ADVANCE ONLINE EDITION OF NATURE GENETICS). THE CONAWAY LAB, IN COLLABORATION WITH THE PROTEOMICS CENTER, THE SHILATIFARD LAB AND THE KRUMLAUF LAB, IDENTIFIED THE MOLECULAR LINCH PIN THAT ALLOWS RNA POLYMERASE II TO SHIFT FROM A STATIC STATE TO AN ACTIVE, GENE-EXPRESSION MODE (PUBLISHED IN THE JULY 8 ISSUE OF CELL) THE SHILATIFARD LAB PINPOINTED THE SUPER ELONGATION COMPLEX AS A MAJOR REGULATOR IN THE COORDINATED EXPRESSION OF EARLY DEVELOPMENTAL GENES. (PUBLISHED IN THE JULY 15 ISSUE OF GENES & DEVELOPMENT). THE WORKMAN LAB, IN COLLABORATION WITH THE PROTEOMICS CENTER, THE SHILATIFARD AND THE CONAWAY LAB, REPORTED THAT THE HIGHLY CONSERVED COACTIVATOR SAGA, BEST CHARACTERIZED FOR LENDING A HELPING HAND DURING THE EARLY STEPS OF TRANSCRIPTIONAL INITIATION IN YEAST, PLAYS AN IMPORTANT ROLE IN TISSUE-SPECIFIC GENE EXPRESSION IN FRUIT FLIES (PUBLISHED IN THE JULY 15 ISSUE OF GENES & DEVELOPMENT). THE SANCHZ ALVARADO LAB DEMONSTRATED HOW THE FLATWORM SCHMIDTEA MEDITERRANEA REGENERATES ITS EXCRETORY SYSTEM FROM SCRATCH PROVIDING NEW CLUES ABOUT THE EVOLUTIONARY ORIGIN OF MAMMALIAN KIDNEYS (PUBLISHED IN THE AUGUST 9 ISSUE OF THE JOURNAL DEVELOPMENT). THE RONG LI LAB DISCOVERED THAT A POWERFUL INTRACELLULAR STREAM PUSHES CHROMOSOMES FAR-OFF THE CENTER IN PREPARATION FOR THE HIGHLY ASYMMETRIC CELL DIVISION THAT COMPLETES OOCYTE MATURATION UPON FERTILIZATION OF THE EGG (PUBLISHED IN THE AUGUST 28 ADVANCE ONLINE EDITION OF NATURE CELL BIOLOGY). THE LINHENG LI LAB TEASED APART THE MOLECULAR MECHANISMS ENABLING STEM CELL RENEWAL IN HEMATOPOIETIC STEM CELLS ISOLATED FROM MICE AND SUCCESSFULLY APPLIED THE INSIGHT TO EXPAND CULTURED HEMATOPOIETIC STEM CELLS A HUNDREDFOLD (PUBLISHED IN THE SEPTEMBER 15 ISSUE OF GENES & DEVELOPMENT). THE HAWLEY LAB CLARIFIED THE ROLE OF KEY CHROMOSOMAL REGIONS CALLED CENTROMERES IN THE FORMATION OF THE STRUCTURE THAT ALLOWS CHROMOSOMES TO PAIR UP DURING AN EARLY AND CRITICAL STEP OF MEIOSIS (PUBLISHED IN THE NOVEMBER 8 ISSUE OF CURRENT BIOLOGY). THE JASPERSEN LAB DEMONSTRATED THAT A PROTEIN KNOWN AS MPS3 NOT ONLY ENSURES THAT CELLS HAVE TWO FUNCTIONAL SPINDLE POLE BODIES, WHICH GENERATE THE MITOTIC SPINDLE APPARATUS THAT HELPS PULL THE CHROMOSOMES APART, BUT ALSO THAT BOTH SPINDLE POLE BODIES ARE PROPERLY ANCHORED IN THE NUCLEAR MEMBRANE (PUBLISHED IN THE NOV. 17 ISSUE OF PLOS GENETICS). THE RONG LI LAB REPORTED THAT THE LIMITED MOBILITY OF CLUMPS OF DAMAGED PROTEINS AND YEAST CELLS' GEOMETRY-THE NARROWNESS OF THE CONNECTION (BUD NECK) BETWEEN THE MOTHER AND THE DAUGHTER BEFORE THEIR SEPARATION, IN PARTICULAR-ARE SUFFICIENT TO ENSURE THAT PROTEIN AGGREGATES ACCUMULATED DURING THE NORMAL AGING PROCESS ARE RETAINED IN THE MOTHER CELL DURING CELL DIVISION (NOVEMBER 23, 2011, ISSUE OF CELL). THE SHILATIFARD LAB FOUND EVIDENCE THAT FOR EACH CLASS OF GENES TRANSCRIBED BY RNA POLYMERASE II THERE EXISTS A SPECIFIC CLASS OF ELONGATION FACTORS (PUBLISHED IN THE DECEMBER 23 ISSUE OF MOLECULAR CELL).
FORM 990, PART III, LINE 4 CONT.		COMPREHENSIVE LIST OF 2011 ORIGINAL RESEARCH PAPERS; REVIEWS, COMMENTARIES OR CHAPTERS; AND BOOKS ORIGINAL RESEARCH PAPERS: BEAR J, RUBINSTEIN B, FEL L. CAPILLARY PRESSURE CURVE FOR LIQUID MENISCI IN A CUBIC ASSEMBLY OF SPHERICAL PARTICLES BELOW IRREDUCIBLE SATURATION. TRANSPORT IN POROUS MEDIA. 2011;89:63-73. BENAZERAF B, FRANCOIS P, DENANS N, LITTLE CD, POURQUIE O. [A NON DIRECTIONAL CELL MIGRATION GRADIENT IN THE PRESOMITIC MESODERM CONTRIBUTES TO AXIS ELONGATION IN CHICKEN EMBRYOS]. BIOL AUJOURDHUI. 2011;205:95-103. BERDYGULOVA Z, WESTBLADE LF, FLORENS L, KOONIN EV, CHAIT BT, RAMANCULOV E, WASHBURN MP, DARST SA, SEVERINOV K, MINAKHIN L. TEMPORAL REGULATION OF GENE EXPRESSION OF THE THERMUS THERMOPHILUS BACTERIOPHAGE P23-45. J MOL BIOL. 2011;405:125-142. BROWN WRA, LITI G, ROSA C, JAMES S, ROBERTS I, ROBERT V, JOLLY N, TANG W, BAUMANN P, GREEN C, SCHLEGEL K, YOUNG J, HIRCHAUD F, LEEK S, THOMAS G, BLOMBERG A, WARRINGER J. A GEOGRAPHICALLY DIVERSE COLLECTION OF SCHIZOSACCHAROMYCES POMBE ISOLATES SHOWS LIMITED PHENOTYPIC VARIATION BUT EXTENSIVE KARYOTYPIC DIVERSITY. G3 GENES, GENOMES, GENETICS. 2011;1:615-626. CAPOTOSTI F, GUERNIER S, LAMMERS F, WARIDEL P, CAI Y, JIN J, CONAWAY JW, CONAWAY RC, HERR W. O-GLCNAC TRANSFERASE CATALYZES SITE-SPECIFIC PROTEOLYSIS OF HCF-1. CELL. 2011;144:376-388. CASTRANOVA D, LAWTON A, LAWRENCE C, BAUMANN DP, BEST J, COSCOLLA J, DOHERTY A, RAMOS J, HAKKESTEEG J, WANG C, WILSON C, MALLEY J, WEINSTEIN BM. THE EFFECT OF STOCKING DENSITIES ON REPRODUCTIVE PERFORMANCE IN LABORATORY ZEBRAFISH (DANIO RERIO). ZEBRAFISH. 2011;8:141-146. CHARLES C, HOVORAKOVA M, AHN Y, LYONS DB, MARANGONI P, CHURAVA S, BIEHS B, JHEON A, LESOT H, BALOOCH G, KRUMLAUF R, VIRIOT L, PETERKOVA R, KLEIN OD. REGULATION OF TOOTH NUMBER BY FINE-TUNING LEVELS OF RECEPTOR-TYROSINE KINASE SIGNALING. DEVELOPMENT. 2011;138:4063-4073. CHEN L, CAI Y, JIN J, FLORENS L, SWANSON SK, WASHBURN MP, CONAWAY JW, CONAWAY RC. SUBUNIT ORGANIZATION OF THE HUMAN INO80 CHROMATIN REMODELING COMPLEX: AN EVOLUTIONARY CONSERVED CORE COMPLEX CATALYZES ATP-DEPENDENT NUCLEOSOME REMODELING.. J BIOL CHEM. 2011;286:11283-11289. CHITTULURU JR, CHABAN Y, MONNET-SAKSOUK J, CARROZZA MJ, SAPOUNTZI V, SELLECK W, HUANG J, UTLEY RT, CRAMET M, ALLARD S, CAI G, WORKMAN JL, FRIED MG, TAN S, COTE J, ASTURIAS FJ. STRUCTURE AND NUCLEOSOME INTERACTION OF THE YEAST NUA4 AND PICCOLO-NUA4 HISTONE ACETYLTRANSFERASE COMPLEXES. NAT STRUCT MOL BIOL. 2011;18:1196-1203. COSTESSI A, MAHROUR N, TIJCHON E, STUNNENBERG R, STOEL MA, JANSEN PW, SELA D, MARTIN-BROWN S, WASHBURN MP, FLORENS L, CONAWAY JW, CONAWAY RC, STUNNENBERG HG. THE TUMOUR ANTIGEN PRAME IS A SUBUNIT OF A CUL2 UBIQUITIN LIGASE AND ASSOCIATES WITH ACTIVE NFY PROMOTERS. EMBO J. 2011;30:3786-3798. CUNNINGHAM TJ, CHATZI C, SANDELL LL, TRAINOR PA, DUESTER G. RDH10 MUTANTS DEFICIENT IN LIMB FIELD RETINOIC ACID SIGNALING EXHIBIT NORMAL LIMB PATTERNING BUT DISPLAY INTERDIGITAL WEBBING. DEV DYN.2011;240:1142-1150. FARJO KM, MOISEYEV G, NIKOLAEVA O, SANDELL LL, TRAINOR PA, MA JX. RDH10 IS THE PRIMARY ENZYME RESPONSIBLE FOR THE FIRST STEP OF EMBRYONIC VITAMIN A METABOLISM AND RETINOIC ACID SYNTHESIS. DEV BIOL. 2011;357:347-355. FRIEDERICHS JM, GHOSH S, SMOYER CJ, MCCROSKEY S, MILLER BD, WEAVER KJ, DELVENTHAL KM, UNRUH J, SLAUGHTER BD, JASPERSEN SL. THE SUN PROTEIN MPS3 IS REQUIRED FOR SPINDLE POLE BODY INSERTION INTO THE NUCLEAR MEMBRANE AND NUCLEAR ENVELOPE HOMEOSTASIS. PLOS GENET. 2011;7:E1002365. GAO JT, GUIMERA R, LI H, PINTO IM, SALES-PARDO M, WAI SC, RUBINSTEIN B, LI R. MODULAR COHERENCE OF PROTEIN DYNAMICS IN YEAST CELL POLARITY SYSTEM. PROC NATL ACAD SCI U S A. 2011;108:7647-7652. GARDNER JM, SMOYER CJ, STENSRUD ES, ALEXANDER R, GOGOL M, WIEGRAEBE W, JASPERSEN SL. TARGETING OF THE SUN PROTEIN MPS3 TO THE INNER NUCLEAR MEMBRANE BY THE HISTONE VARIANT H2A.Z. J CELL BIOL. 2011;193:489-507. GIBSON WT, VELDHUIS JH, RUBINSTEIN B, CARTWRIGHT HN, PERRIMON N, BRODLAND GW, NAGPAL R, GIBSON MC. CONTROL OF MITOTIC CLEAVAGE PLANE BY LOCAL EPITHELIAL TOPOLOGY. CELL. 2011;144:427-438. GILMORE JM, SARDIU ME, VENKATESH S, STUTZMAN B, PEAK A, SEIDEL CW, WORKMAN JL, FLORENS L, WASHBURN MP. CHARACTERIZATION OF A HIGHLY CONSERVED HISTONE RELATED PROTEIN, YDL156W, AND ITS FUNCTIONAL ASSOCIATIONS USING QUANTITATIVE PROTEOMIC ANALYSES [PUBLISHED AHEAD OF PRINT DECEMBER 22 2011]. MOL CELL PROTEOMICS. 2011. GRAVELEY BR, BROOKS AN, CARLSON JW, DUFF MO, LANDOLIN JM, YANG L, ARTIERI CG, VAN BAREN MJ, BOLEY N, BOOTH BW, BROWN JB, CHERBAS L, DAVIS CA, DOBIN A, LI R, LIN W, MALONE JH, MATTIUZZO NR, MILLER D, STURGILL D, TUCH BB, ZALESKI C, ZHANG D, BLANCHETTE M, DUDOIT S, EADS B, GREEN RE, HAMMONDS A, JIANG L, KAPRANOV P, LANGTON L, PERRIMON N, SANDLER JE, WAN KH, WILLINGHAM A, ZHANG Y, ZOU Y, ANDREWS J, BICKEL PJ, BRENNER SE, BRENT MR, CHERBAS P, GINGERAS TR, HOSKINS RA, KAUFMAN TC, OLIVER B, CELNIKER SE. THE DEVELOPMENTAL TRANSCRIPTOME OF DROSOPHILA MELANOGASTER. NATURE. 2011;471:473-479.
FORM 990, PART III, LINE 4 CONT.		HAO Y, XU N, BOX A, SCHAEFER L, KANNAN K, ZHANG Y, FLORENS L, SEIDEL C, WASHBURN M, WIEGRAEBE W, MAK HY. NUCLEAR CGMP-DEPENDENT KINASE REGULATES GENE EXPRESSION VIA ACTIVITY-DEPENDENT RECRUITMENT OF A CONSERVED HISTONE DEACETYLASE COMPLEX. PLOS GENET. 2011;7:E1002065. HARALALKA S, SHELTON C, CARTWRIGHT HN, KATZFEY E, JANZEN E, ABMAYR SM. ASYMMETRIC MBC, ACTIVE RAC1 AND F-ACTIN FOCI IN THE FUSION-COMPETENT MYOBLASTS DURING MYOBLAST FUSION IN DROSOPHILA. DEVELOPMENT. 2011;138:1551 - 1562. HE Q, BARDET AF, PATTON B, PURVIS J, JOHNSTON J, PAULSON A, GOGOL M, STARK A, ZEITLINGER J. HIGH CONSERVATION OF TRANSCRIPTION FACTOR BINDING AND EVIDENCE FOR COMBINATORIAL REGULATION ACROSS SIX DROSOPHILA SPECIES. NAT GENET. 2011;43:414-420. HOCHHEISER H, ARONOW BJ, ARTINGER K, BEATY TH, BRINKLEY JF, CHAI Y, CLOUTHIER D, CUNNINGHAM ML, DIXON M, DONAHUE LR, FRASER SE, HALLGRIMSSON B, IWATA J, KLEIN O, MARAZITA ML, MURRAY JC, MURRAY S, DE VILLENA FP, POSTLETHWAIT J, POTTER S, SHAPIRO L, SPRITZ R, VISEL A, WEINBERG SM, TRAINOR PA. THE FACEBASE CONSORTIUM: A COMPREHENSIVE PROGRAM TO FACILITATE CRANIOFACIAL RESEARCH. DEV BIOL. 2011;355:175-182. HRECKA K, HAO C, GIERSZEWSKA M, SWANSON SK, KESIK-BRODACKA M, SRIVASTAVA S, FLORENS L, WASHBURN MP, SKOWRONSKI J. VPX RELIEVES INHIBITION OF HIV-1 INFECTION OF MACROPHAGES MEDIATED BY THE SAMHD1 PROTEIN. NATURE. 2011;474:658-661. HUGHES SE, BEELER JS, SEAT A, SLAUGHTER BD, UNRUH JR, BAUERLY E, MATTHIES HJ, HAWLEY RS. GAMMA-TUBULIN IS REQUIRED FOR BIPOLAR SPINDLE ASSEMBLY AND FOR PROPER KINETOCHORE MICROTUBULE ATTACHMENTS DURING PROMETAPHASE I IN DROSOPHILA OOCYTES. PLOS GENET. 2011;7:E1002209. KANNAN L, LI H, MUSHEGIAN A. A POLYNOMIAL-TIME ALGORITHM COMPUTING LOWER AND UPPER BOUNDS OF THE ROOTED SUBTREE PRUNE AND REGRAFT DISTANCE. J COMPUT BIOL. 2011;18:743-757. KECK JM, JONES MH, WONG CC, BINKLEY J, CHEN D, JASPERSEN SL, HOLINGER EP, XU T, NIEPEL M, ROUT MP, VOGEL J, SIDOW A, YATES JR, 3RD, WINEY M. A CELL CYCLE PHOSPHOPROTEOME OF THE YEAST CENTROSOME. SCIENCE. 2011;332:1557-1561. KIRILLY D, WANG S, XIE T. SELF-MAINTAINED ESCORT CELLS FORM A GERMLINE STEM CELL DIFFERENTIATION NICHE. DEVELOPMENT. 2011;138:5087-5097. KIM S, MA L, YU CR. REQUIREMENT OF CALCIUM-ACTIVATED CHLORIDE CHANNELS IN THE ACTIVATION OF THE MOUSE VOMERONASAL NEURON. NAT COMMUN [SERIAL ONLINE]. 2011;2:365. DOI:10.1038/NCOMMS1368. KRISTENSEN DM, CAI X, MUSHEGIAN A. EVOLUTIONARILY CONSERVED ORTHOLOGOUS FAMILIES IN PHAGES ARE RELATIVELY RARE IN THEIR PROKARYOTIC HOSTS. J BACTERIOL. 2011;193:1806-1814. KROL AJ, ROELLIG D, DEQUEANT ML, TASSY O, GLYNN E, HATTEM G, MUSHEGIAN A, OATES AC, POURQUIE O. EVOLUTIONARY PLASTICITY OF SEGMENTATION CLOCK NETWORKS. DEVELOPMENT. 2011;138:2783-2792. LAKE CM, NIELSEN RJ, HAWLEY RS. THE DROSOPHILA ZINC FINGER PROTEIN TRADE EMBARGO IS REQUIRED FOR DOUBLE STRAND BREAK FORMATION IN MEIOSIS. PLOS GENET. 2011;7:E1002005. LEE KK, SARDIU ME, SWANSON SK, GILMORE JM, TOROK M, GRANT PA, FLORENS L, WORKMAN JL, WASHBURN MP. COMBINATORIAL DEPLETION ANALYSIS TO ASSEMBLE THE NETWORK ARCHITECTURE OF THE SAGA AND ADA CHROMATIN REMODELING COMPLEXES. MOL SYST BIOL. 2011;7:503. LIN C, GARRETT AS, DE KUMAR B, SMITH ER, GOGOL M, SEIDEL C, KRUMLAUF R, SHILATIFARD A. DYNAMIC TRANSCRIPTIONAL EVENTS IN EMBRYONIC STEM CELLS MEDIATED BY THE SUPER ELONGATION COMPLEX (SEC). GENES DEV. 2011;25:1486-1498. LITOVCHICK L, FLORENS LA, SWANSON SK, WASHBURN MP, DECAPRIO JA. DYRK1A PROTEIN KINASE PROMOTES QUIESCENCE AND SENESCENCE THROUGH DREAM COMPLEX ASSEMBLY. GENES DEV. 2011;25:801-813. LUTES AA, BAUMANN DP, NEAVES WB, BAUMANN P. FROM THE COVER: LABORATORY SYNTHESIS OF AN INDEPENDENTLY REPRODUCING VERTEBRATE SPECIES. PROC NATL ACAD SCI U S A. 2011;108:9910-9915. MCKINNEY MC, STARK DA, TEDDY J, KULESA PM. NEURAL CREST CELL COMMUNICATION INVOLVES AN EXCHANGE OF CYTOPLASMIC MATERIAL THROUGH CELLULAR BRIDGES REVEALED BY PHOTOCONVERSION OF KIKGR. DEV DYN. 2011;240:1391-1401. MCKINNEY MC, KULESA PM. IN VIVO CALCIUM DYNAMICS DURING NEURAL CREST CELL MIGRATION AND PATTERNING USING GCAMP3. DEV BIOL. 2011;358:309-317. MEYER EJ, IKMI A, GIBSON MC. INTERKINETIC NUCLEAR MIGRATION IS A BROADLY CONSERVED FEATURE OF CELL DIVISION IN PSEUDOSTRATIFIED EPITHELIA. CURR BIOL. 2011;21:485-491.
FORM 990, PART III, LINE 4 CONT.		MOHAN M, HERZ HM, SMITH ER, ZHANG Y, JACKSON J, WASHBURN MP, FLORENS L, EISSENBERG JC, SHILATIFARD A. THE COMPASS FAMILY OF H3K4 METHYLASES IN DROSOPHILA. MOL CELL BIOL. 2011;31:4310-4318. MOSLEY AL, SARDIU ME, PATTENDEN SG, WORKMAN JL, FLORENS L, WASHBURN MP. HIGHLY REPRODUCIBLE LABEL FREE QUANTITATIVE PROTEOMIC ANALYSIS OF RNA POLYMERASE COMPLEXES. MOL CELL PROTEOMICS. 2011;10:M110 000687. PARRISH M, UNRUH J, KRUMLAUF R. BAC MODIFICATION THROUGH SERIAL OR SIMULTANEOUS USE OF CRE/LOX TECHNOLOGY. J BIOMED BIOTECHNOL. 2011;2011:924068. PERRY JM, HE XC, SUGIMURA R, GRINDLEY JC, HAUG JS, DING S, LI L. COOPERATION BETWEEN BOTH WNT/{BETA}-CATENIN AND PTEN/PI3K/AKT SIGNALING PROMOTES PRIMITIVE HEMATOPOIETIC STEM CELL SELF-RENEWAL AND EXPANSION. GENES DEV. 2011;25:1928-1942. PONTS N, SARAF A, CHUNG DW, HARRIS A, PRUDHOMME J, WASHBURN MP, FLORENS L, LE ROCH KG. UNRAVELING THE UBIQUITOME OF THE HUMAN MALARIA PARASITE. J BIOL CHEM. 2011;286:40320-40330. POTAPOVA TA, SIVAKUMAR S, FLYNN JN, LI R, GORBSKY GJ. MITOTIC PROGRESSION BECOMES IRREVERSIBLE IN PROMETAPHASE AND COLLAPSES WHEN WEE1 AND CDC25 ARE INHIBITED. MOL BIOL CELL. 2011;22:1191-1206. REMBOUTSIKA E, ELKOURIS M, IULIANELLA A, ANDONIADOU CL, POULOU M, MITSIADIS TA, TRAINOR PA, LOVELL-BADGE R. FLEXIBILITY OF NEURAL STEM CELLS. FRONT PHYSIOL. 2011;2:16. RHIND N, CHEN Z, YASSOUR M, THOMPSON DA, HAAS BJ, HABIB N, WAPINSKI I, ROY S, LIN MF, HEIMAN DI, YOUNG SK, FURUYA K, GUO Y, PIDOUX A, CHEN HM, ROBBERTSE B, GOLDBERG JM, AOKI K, BAYNE EH, BERLIN AM, DESJARDINS CA, DOBBS E, DUKAJ L, FAN L, FITZGERALD MG, FRENCH C, GUJJA S, HANSEN K, KEIFENHEIM D, LEVIN JZ, MOSHER RA, MULLER CA, PFIFFNER J, PRIEST M, RUSS C, SMIALOWSKA A, SWOBODA P, SYKES SM, VAUGHN M, VENGROVA S, YODER R, ZENG Q, ALLSHIRE R, BAULCOMBE D, BIRREN BW, BROWN W, EKWALL K, KELLIS M, LEATHERWOOD J, LEVIN H, MARGALIT H, MARTIENSSEN R, NIEDUSZYNSKI CA, SPATAFORA JW, FRIEDMAN N, DALGAARD JZ, BAUMANN P, NIKI H, REGEV A, NUSBAUM C. COMPARATIVE FUNCTIONAL GENOMICS OF THE FISSION YEASTS. SCIENCE. 2011;332:930-936. RUBINSTEIN BY, LESHANSKY AM. RUPTURE OF THIN LIQUID FILMS: GENERALIZATION OF WEAKLY NONLINEAR THEORY. PHYS REV E STAT NONLIN SOFT MATTER PHYS. 2011;83:031603. SANDELL LL, IULIANELLA A, MELTON KR, LYNN M, WALKER M, INMAN KE, BHATT S, LEROUX-BERGER M, CRAWFORD M, JONES NC, DENNIS JF, TRAINOR PA. A PHENOTYPE-DRIVEN ENU MUTAGENESIS SCREEN IDENTIFIES NOVEL ALLELES WITH FUNCTIONAL ROLES IN EARLY MOUSE CRANIOFACIAL DEVELOPMENT. GENESIS. 2011;49:342-359. SHIVARAJU M, CAMAHORT R, MATTINGLY M, GERTON JL. SCM3 IS A CENTROMERIC NUCLEOSOME ASSEMBLY FACTOR. J BIOL CHEM. 2011;286:12016-12023. SMITH ER, LIN C, GARRETT AS, THORNTON J, MOHAGHEGH N, HU D, JACKSON J, SARAF A, SWANSON SK, SEIDEL C, FLORENS L, WASHBURN MP, EISSENBERG JC, SHILATIFARD A. THE LITTLE ELONGATION COMPLEX REGULATES SMALL NUCLEAR RNA TRANSCRIPTION. MOL CELL. 2011;44:954-965. SZUPERAK M, SALAH S, MEYER EJ, NAGARAJAN U, IKMI A, GIBSON MC. FEEDBACK REGULATION OF DROSOPHILA BMP SIGNALING BY THE NOVEL EXTRACELLULAR PROTEIN LARVAL TRANSLUCIDA. DEVELOPMENT. 2011;138:715-724. TAKAHASHI YH, WESTFIELD GH, OLESKIE AN, TRIEVEL RC, SHILATIFARD A, SKINIOTIS G. STRUCTURAL ANALYSIS OF THE CORE COMPASS FAMILY OF HISTONE H3K4 METHYLASES FROM YEAST TO HUMAN. PROC NATL ACAD SCI U S A. 2011;108:20526-20531. TAKAHASHI H, PARMELY TJ, SATO S, TOMOMORI-SATO C, BANKS CA, KONG SE, SZUTORISZ H, SWANSON SK, MARTIN-BROWN S, WASHBURN MP, FLORENS L, SEIDEL CW, LIN C, SMITH ER, SHILATIFARD A, CONAWAY RC, CONAWAY JW. HUMAN MEDIATOR SUBUNIT MED26 FUNCTIONS AS A DOCKING SITE FOR TRANSCRIPTION ELONGATION FACTORS. CELL. 2011;146:92-104. TAKAHASHI YH, SCHULZE JM, JACKSON J, HENTRICH T, SEIDEL C, JASPERSEN SL, KOBOR MS, SHILATIFARD A. DOT1 AND HISTONE H3K79 METHYLATION IN NATURAL TELOMERIC AND HM SILENCING. MOL CELL. 2011;42:118-126. TAKEO S, LAKE CM, MORAIS-DE-SA E, SUNKEL CE, HAWLEY RS. SYNAPTONEMAL COMPLEX-DEPENDENT CENTROMERIC CLUSTERING AND THE INITIATION OF SYNAPSIS IN DROSOPHILA OOCYTES. CURR BIOL. 2011. TALIAFERRO JM, ALVAREZ N, GREEN RE, BLANCHETTE M, RIO DC. EVOLUTION OF A TISSUE-SPECIFIC SPLICING NETWORK. GENES DEV. 2011;25:608-620. VOGELWEID CM, ZAPIEN KA, HONIGFORD MJ, LI L, LI H, MARSHALL H. EFFECTS OF A 28-DAY CAGE-CHANGE INTERVAL ON INTRACAGE AMMONIA LEVELS, NASAL HISTOLOGY, AND PERCEIVED WELFARE OF CD1 MICE. J AM ASSOC LAB ANIM SCI. 2011;50:868-878. WANG X, PAN L, WANG S, ZHOU J, MCDOWELL W, PARK J, HAUG J, STAEHLING K, TANG H, XIE T. HISTONE H3K9 TRIMETHYLASE EGGLESS CONTROLS GERMLINE STEM CELL MAINTENANCE AND DIFFERENTIATION. PLOS GENET. 2011;7:E1002426.
FORM 990, PART III, LINE 4 CONT.		WEAKE VM, DYER JO, SEIDEL C, BOX A, SWANSON SK, PEAK A, FLORENS L, WASHBURN MP, ABMAYR SM, WORKMAN JL. POST-TRANSCRIPTION INITIATION FUNCTION OF THE UBIQUITOUS SAGA COMPLEX IN TISSUE-SPECIFIC GENE ACTIVATION. GENES DEV. 2011;25:1499-1509. WILKIE GS, KORFALI N, SWANSON SK, MALIK P, SRSEN V, BATRAKOU DG, DE LAS HERAS J, ZULEGER N, KERR AR, FLORENS L, SCHIRMER EC. SEVERAL NOVEL NUCLEAR ENVELOPE TRANSMEMBRANE PROTEINS IDENTIFIED IN SKELETAL MUSCLE HAVE CYTOSKELETAL ASSOCIATIONS. MOL CELL PROTEOMICS. 2011;10:M110 003129. WOOD C, HUFF J, MARSHALL W, YU EQ, UNRUH J, SLAUGHTER B, WIEGRAEBE W. FLUORESCENCE CORRELATION SPECTROSCOPY AS TOOL FOR HIGH-CONTENT-SCREENING IN YEAST (HCS-FCS). PROC SPIE; 2011;7905, 79050H. XU XP, ROUILLER I, SLAUGHTER BD, EGILE C, KIM E, UNRUH JR, FAN X, POLLARD TD, LI R, HANEIN D, VOLKMANN N. THREE-DIMENSIONAL RECONSTRUCTIONS OF ARP2/3 COMPLEX WITH BOUND NUCLEATION PROMOTING FACTORS. EMBO J. 2012;31:236-247. YI K, UNRUH JR, DENG M, SLAUGHTER BD, RUBINSTEIN B, LI R. DYNAMIC MAINTENANCE OF ASYMMETRIC MEIOTIC SPINDLE POSITION THROUGH ARP2/3-COMPLEX-DRIVEN CYTOPLASMIC STREAMING IN MOUSE OOCYTES. NAT CELL BIOL. 2011;13:1252-1258. YU Y, SRINIVASAN M, NAKANISHI S, LEATHERWOOD J, SHILATIFARD A, STERNGLANZ R. A CONSERVED PATCH NEAR THE C TERMINUS OF HISTONE H4 IS REQUIRED FOR GENOME STABILITY IN BUDDING YEAST. MOL CELL BIOL. 2011;31:2311-2325. ZHOU C, SLAUGHTER BD, UNRUH JR, ELDAKAK A, RUBINSTEIN B, LI R. MOTILITY AND SEGREGATION OF HSP104-ASSOCIATED PROTEIN AGGREGATES IN BUDDING YEAST. CELL. 2011;147:1186-1196. ZHU HH, JI K, ALDERSON N, HE Z, LI S, LIU W, ZHANG DE, LI L, FENG GS. KIT-SHP2-KIT SIGNALING ACTS TO MAINTAIN A FUNCTIONAL HEMATOPOIETIC STEM AND PROGENITOR CELL POOL. BLOOD. 2011;117:5350-5361. REVIEWS, COMMENTARIES OR CHAPTERS: BRYAN TM, BAUMANN P. G-QUADRUPLEXES: FROM GUANINE GELS TO CHEMOTHERAPEUTICS. MOL BIOTECHNOL. 2011;49:198-208. CHEN S, WANG S, XIE T. RESTRICTING SELF-RENEWAL SIGNALS WITHIN THE STEM CELL NICHE: MULTIPLE LEVELS OF CONTROL. CURR OPIN GENET DEV. 2011;21:684-689. CONAWAY RC, CONAWAY JW. ORIGINS AND ACTIVITY OF THE MEDIATOR COMPLEX. SEMIN CELL DEV BIOL. 2011;22:729-734. CONAWAY RC, CONAWAY JW. FUNCTION AND REGULATION OF THE MEDIATOR COMPLEX. CURR OPIN GENET DEV. 2011;21:225-230. GKIKOPOULOS T, SCHOFIELD P, SINGH V, PINSKAYA M, MELLOR J, SMOLLE M, WORKMAN JL, BARTON GJ, OWEN-HUGHES T. A ROLE FOR SNF2-RELATED NUCLEOSOME-SPACING ENZYMES IN GENOME-WIDE NUCLEOSOME ORGANIZATION. SCIENCE. 2011;333:1758-1760. HARALALKA S, CARTWRIGHT HN, ABMAYR SM. RECENT ADVANCES IN IMAGING EMBRYONIC MYOBLAST FUSION IN DROSOPHILA [PUBLISHED AHEAD OF PRINT AUGUST 30 2011]. METHODS. 2011. HAWLEY RS. MOLECULAR BIOLOGY. HITTING A TINY TARGET IN THE DARK. SCIENCE 2011;331:870-871. HAWLEY RS. OOGENESIS: WHEN MOST IS GOOD ENOUGH. CURR BIOL. 2011;21:R288-290. HAWLEY RS. SOLVING A MEIOTIC LEGO(R) PUZZLE: TRANSVERSE FILAMENTS AND THE ASSEMBLY OF THE SYNAPTONEMAL COMPLEX IN CAENORHABDITIS ELEGANS. GENETICS. 2011;189:405-409. HEWAWASAM GS, GERTON JL. CSE4 GETS A KISS-OF-DEATH FROM PSH1. CELL CYCLE. 2011;10:566-567. HENIKOFF S, SHILATIFARD A. HISTONE MODIFICATION: CAUSE OR COG? TRENDS GENET. 2011;27:389-396. JASPERSEN SL, HAWLEY RS. MEIOTIC PAIRING AS A POLO MATCH. DEV CELL. 2011;21:805-806. KRULL CE, SU F, SWARTZ M, EBERHART J, MCLENNAN R, CHEN Y, TRAINOR PA. ELECTROPORATION OF CHICK AND MOUSE EMBRYOS. IN: J SHARPE, AND RO WONG, EDS. IMAGING IN DEVELOPMENTAL BIOLOGY: A LABORATORY MANUAL. COLD SPRING HARBOR, N.Y.: COLD SPRING HARBOR LABORATORY PRESS; 2011. KULESA PM, DICKINSON ME, HADJANTONAKIS AK. HIGHLIGHTS OF THE SPECIAL IMAGING ISSUE. GENESIS. 2011;49:479-483. KWAK J, WORKMAN JL, LEE D. THE PROTEASOME AND ITS REGULATORY ROLES IN GENE EXPRESSION. BIOCHIM BIOPHYS ACTA. 2011;1809:88-96. KWON SH, WORKMAN JL. HP1C CASTS LIGHT ON DARK MATTER. CELL CYCLE. 2011;10:625-630. KWON SH, WORKMAN JL. THE CHANGING FACES OF HP1: FROM HETEROCHROMATIN FORMATION AND GENE SILENCING TO EUCHROMATIC GENE EXPRESSION: HP1 ACTS AS A POSITIVE REGULATOR OF TRANSCRIPTION. BIOESSAYS. 2011;33:280-289.
FORM 990, PART III, LINE 4 CONT.		LIN CH, WORKMAN JL. SUPPRESSION OF CRYPTIC INTRAGENIC TRANSCRIPTS IS REQUIRED FOR EMBRYONIC STEM CELL SELF-RENEWAL. EMBO J. 2011;30:1420-1421. MA L, HAGA-YAMANAKA S, YU Q-E, QIU Q, KIM S, YU CR. IMAGING NEURONAL RESPONSES IN SLICE PREPARATIONS OF VOMERONASAL ORGAN EXPRESSING A GENETICALLY ENCODED CALCIUM SENSOR. J VIS EXP. 2011;58. MUSHEGIAN A, CONAWAY JW. THEMATIC MINIREVIEW SERIES ON COMPUTATIONAL SYSTEMS BIOLOGY. J BIOL CHEM. 2011;286:23621-23622. NEAVES WB, BAUMANN P. UNISEXUAL REPRODUCTION AMONG VERTEBRATES. TRENDS GENET. 2011;27:81-88. RAMISETTY SR, WASHBURN MP. UNRAVELING THE DYNAMICS OF PROTEIN INTERACTIONS WITH QUANTITATIVE MASS SPECTROMETRY. CRIT REV BIOCHEM MOL BIOL. 2011;46:216-228. SARDIU ME, WASHBURN MP. BUILDING PROTEIN-PROTEIN INTERACTION NETWORKS WITH PROTEOMICS AND INFORMATICS TOOLS. J BIOL CHEM. 2011;286:23645-23651. SARDIU ME, WASHBURN MP. CONSTRUCTION OF PROTEIN INTERACTION NETWORKS BASED ON THE LABEL-FREE QUANTITATIVE PROTEOMICS. METHODS MOL BIOL. 2011;781:71-85. SHIVARAJU M, GERTON GL. THE DYNAMICS OF THE CSE4 CHAPERONE SCM3. CELL CYCLE. 2011;10:3369-3378. SUGIMURA R, LI L. BONE METASTASIS TARGETS THE ENDOSTEAL HEMATOPOIETIC STEM CELL NICHE. IBMS BONEKEY. 2011;8:381-384. STRIZZI L, HARDY KM, SEFTOR EA, MARGARYAN NV, KIRSCHMANN DA, KIRSAMMER GT, BAILEY CM, KASEMEIER-KULESA JC, KULESA PM, SEFTOR REB, HENDRIX MJC. LESSONS FROM EMBYOGENESIS. IN: A BOSSERHOFF, ED. MELANOMA DEVELOPMENT - MOLECULAR BIOLOGY, GENETICS AND CLINICAL APPLICATIONS: SPRINGER-VERLAG/WIEN; 2011:281-296. SLAUGHTER BD, UNRUH JR, LI R. FLUORESCENCE FLUCTUATION SPECTROSCOPY AND IMAGING METHODS FOR EXAMINATION OF DYNAMIC PROTEIN INTERACTIONS IN YEAST. METHODS MOL BIOL. 2011;759:283-306. SMITH E, LIN C, SHILATIFARD A. THE SUPER ELONGATION COMPLEX (SEC) AND MLL IN DEVELOPMENT AND DISEASE. GENES DEV. 2011;25:661-672. SMOLLE M, WORKMAN JL. SIGNALING THROUGH CHROMATIN: SETTING THE SCENE AT KINETOCHORES. CELL. 2011;146:671-672. SUGANUMA T, WORKMAN JL. SIGNALS AND COMBINATORIAL FUNCTIONS OF HISTONE MODIFICATIONS. ANNU REV BIOCHEM. 2011;80:473-499. WASHBURN MP. DRIVING BIOCHEMICAL DISCOVERY WITH QUANTITATIVE PROTEOMICS. TRENDS BIOCHEM SCI. 2010;36:170-177. WEAKE VM, WORKMAN JL. SAGA FUNCTION IN TISSUE-SPECIFIC GENE EXPRESSION [PUBLISHED AHEAD OF PRINT DECEMBER 27 2011]. TRENDS CELL BIOL. 2011. XIONG B. SPC25: HOW THE KINETOCHORE PROTEIN PLAYS DURING OOCYTE MEIOSIS. CELL CYCLE. 2011;10:1031-1030. YUN M, WU J, WORKMAN JL, LI B. READERS OF HISTONE MODIFICATIONS. CELL RES. 2011;21:564-578. ZHOU Y, LU T, XIE T. A PGC-1 TALE: HEALTHIER INTESTINAL STEM CELLS, LONGER LIFE. CELL METAB. 2011;14:571-572. BOOK: RICHARDS JE, HAWLEY RS. THE HUMAN GENOME, A USER'S GUIDE. THIRD ED: ACADEMIC PRESS; 2011.
FORM 990, PART III, LINE 4 CONT.	COMPETITIVE RESEARCH GRANT FUNDING & RESEARCH AWARDS & DISTINCTIONS	THE ABILITY OF STOWERS INSTITUTE SCIENTISTS TO RECEIVE INCREASING NUMBERS OF COMPETITIVELY AWARDED RESEARCH GRANTS ATTESTS TO THE HIGH LEVEL OF RESEARCH PRODUCTIVITY PRESENT AT THE INSTITUTE. DURING 2011, STOWERS SCIENTISTS WORKED WITH THE SUPPORT OF 24 GRANTS AND FELLOWSHIPS FROM THE NATIONAL INSTITUTES OF HEALTH, FOUR GRANTS AND FELLOWSHIPS FROM THE AMERICAN CANCER SOCIETY, ONE AWARD FROM ALEX'S LEMONADE STAND FOUNDATION, ONE FELLOWSHIP FROM THE LEUKEMIA AND LYMPHOMA SOCIETY, ONE FELLOWSHIP FROM THE AMERICAN HEART ASSOCIATION, ONE FELLOWSHIP FROM THE AMERICAN ASSOCIATION OF ANATOMISTS, ONE FELLOWSHIP FROM THE LIFE SCIENCES RESEARCH FOUNDATION, ONE FELLOWSHIP FROM THE DAMON RUNYON CANCER RESEARCH FOUNDATION, ONE AWARD FROM THE MCKNIGHT FOUNDATION, ONE AWARD FROM THE ELLISON MEDICAL FOUNDATION, ONE GRANT FROM THE GREATER KANSAS CITY COMMUNITY FOUNDATION, ONE HUDSON PRIZE FROM THE M.R. AND EVELYN HUDSON FOUNDATION, ONE AWARD FROM THE KANSAS CITY AREA LIFE SCIENCES INSTITUTE, ONE MARCH OF DIMES AWARD, ONE AWARD FROM THE MIDWEST CANCER ALLIANCE, ONE PEW SCHOLAR AWARD, ONE AWARD FROM THE BURROUGHS WELLCOME FUND, TWO INVESTIGATOR AWARDS FROM THE HOWARD HUGHES MEDICAL INSTITUTE, AND ONE FELLOWSHIP FROM THE JANE COFFIN CHILDS MEMORIAL FUND. WITH NEW AND RECURRING GRANT SUPPORT, THE INSTITUTE IS RECEIVING MORE THAN $7 MILLION A YEAR IN RESEARCH FUNDING TO SUPPLEMENT THE INCOME FROM ITS ENDOWMENTS. TESTIFYING TO THE HIGH LEVEL OF ACHIEVEMENT TAKING PLACE AT THE INSTITUTE ARE THE AWARDS AND HONORS INSTITUTE SCIENTISTS RECEIVED IN 2011: - ELIZABETH DUNCAN, PH.D., POSTDOCTORAL RESEARCH ASSOCIATE IN THE SNCHEZ ALVARADO LAB, TRANSFERRED A DAMON RUNYON CANCER RESEARCH FOUNDATION FELLOWSHIP TO THE INSTITUTE, EFFECTIVE IN JUNE. - JAMIE DYER, PH.D., POSTDOCTORAL RESEARCH ASSOCIATE IN THE WORKMAN LAB, RECEIVED A RUTH L. KIRSCHSTEIN NATIONAL RESEARCH SERVICE AWARD FROM THE NATIONAL INSTITUTES OF HEALTH, EFFECTIVE IN JULY. - MATT GIBSON, PH.D., ASSOCIATE INVESTIGATOR, RECEIVED THE 2011 HUDSON PRIZE FROM THE M.R. AND EVELYN HUDSON FOUNDATION, EFFECTIVE IN JULY. - SUE JASPERSEN, PH.D., ASSISTANT INVESTIGATOR, RECEIVED AN AMERICAN CANCER SOCIETY RESEARCH SCHOLAR GRANT, EFFECTIVE IN JANUARY. - RAM KANNAN, PREDOCTORAL RESEARCHER IN THE BAUMAN LAB, RECEIVED AN AMERICAN HEART ASSOCIATION MIDWEST AFFILIATE PREDOCTORAL FELLOWSHIP, EFFECTIVE IN JULY. - LINHENG LI, PH.D., INVESTIGATOR, RECEIVED A NATIONAL INSTITUTES OF HEALTH GRANT, EFFECTIVE IN SEPTEMBER. - TATJANA PIOTROWSKI, PH.D., ASSOCIATE INVESTIGATOR, JOINED THE INSTITUTE AND TRANSFERRED A NATIONAL INSTITUTES OF HEALTH GRANT AND AMERICAN CANCER SOCIETY SCHOLAR RESEARCH AWARD TO THE INSTITUTE, EFFECTIVE IN JUNE. - ALEJANDRO SNCHEZ, PH.D., INVESTIGATOR, JOINED THE STOWERS INSTITUTE AND TRANSFERRED A NATIONAL INSTITUTES OF HEALTH GRANT, EFFECTIVE IN JUNE AND A SENIOR SCHOLAR AWARD IN AGING FROM THE ELLISON MEDICAL FOUNDATION, EFFECTIVE IN SEPTEMBER. - KIMBERLY TU, PH.D. POSTDOCTORAL RESEARCH ASSOCIATE IN THE SNCHEZ ALVARADO LAB, TRANSFERRED TO THE INSTITUTE A FELLOWSHIP FROM THE LIFE SCIENCES RESEARCH FOUNDATION, EFFECTIVE IN JUNE. - JERRY WORKMAN, PH.D., INVESTIGATOR, RECEIVED A NATIONAL INSTITUTES OF HEALTH GRANT, EFFECTIVE IN SEPTEMBER. - SACHIKO YAMANAKA, PH.D., POSTDOCTORAL RESEARCH ASSOCIATE IN THE YU LAB, WAS AWARDED A FELLOWSHIP FROM THE JAPAN SOCIETY FOR THE PROMOTION OF SCIENCE, EFFECTIVE IN JUNE. - RON YU, PH.D., ASSOCIATE INVESTIGATOR, RECEIVED A NATIONAL INSTITUTES OF HEALTH GRANT, EFFECTIVE IN JUNE. - R. SCOTT HAWLEY, PH.D., INVESTIGATOR, WAS ELECTED TO THE NATIONAL ACADEMY OF SCIENCES IN JUNE. - WILLIAM B. NEAVES, PH.D., PRESIDENT EMERITUS, WAS ELECTED TO THE AMERICAN ACADEMY OF ARTS AND SCIENCES.
FORM 990, PART III, LINE 4 CONT.	COOPERATION AGREEMENTS AND COLLABORATIONS	THE STOWERS INSTITUTE CONTINUED COLLABORATIONS IN 2011 WITH HOSPITALS IN KANSAS CITY (CHILDREN'S MERCY, AND ST. LUKE'S) AND BOSTON (MASSACHUSETTS GENERAL HOSPITAL, BRIGHAM AND WOMEN'S HOSPITAL) AND ADDED NEW COLLABORATIONS IN NEW YORK CITY (MEMORIAL SLOAN KETTERING CANCER CENTER), CINCINNATI (CHILDREN'S HOSPITAL MEDICAL CENTER), SEATTLE (CHILDREN'S HOSPITAL AND REGIONAL MEDICAL CENTER) AND STOCKHOLM, SWEDEN (KAROLINSKA UNIVERSITY HOSPITAL). THE INSTITUTE ALSO COLLABORATES WITH THE UNIVERSITY OF MISSOURI AT KANSAS CITY AND COLUMBIA; THE UNIVERSITY OF KANSAS MEDICAL CENTER; THE HOWARD HUGHES MEDICAL INSTITUTE; HARVARD UNIVERSITY; HARVARD MEDICAL SCHOOL; THE CASE SCHOOL OF MEDICINE; DUKE UNIVERSITY SCHOOL OF MEDICINE; JOHN HOPKINS UNIVERSITY; MAYO MEDICAL SCHOOL; THE NEW YORK SCHOOL OF MEDICINE; PENINSULA MEDICAL SCHOOL UNIVERSITIES OF EXETER AND PLYMOUTH; ST. LOUIS UNIVERSITY SCHOOL OF MEDICINE; STANFORD UNIVERSITY; THE UNIVERSITY OF CALIFORNIA, LOS ANGELES AND SAN FRANCISCO; THE UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE; THE UNIVERSITY OF COLORADO AT BOULDER; THE UNIVERSITY OF COLORADO SCHOOL OF MEDICINE; THE UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL; THE UNIVERSITY OF NEBRASKA MEDICAL CENTER; THE UNIVERSITY OF PENNSYLVANIA; THE UNIVERSITY OF VIRGINIA MEDICAL SCHOOL; UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER; VANDERBILT UNIVERSITY SCHOOL OF MEDICINE AND WARWICK MEDICAL SCHOOL, MOST OF WHICH ARE ASSOCIATED WITH TEACHING AND RESEARCH HOSPITALS. IN TOTAL, STOWERS RESEARCHERS SUCCESSFULLY COLLABORATED WITH COLLEAGUES AT 78 NATIONAL AND 63 INTERNATIONAL UNIVERSITIES AND RESEARCH INSTITUTES. IN ADDITION TO THE INSTITUTIONS LISTED ABOVE, COLLABORATORS INCLUDE: AFFYMETRIX; AGILENT TECHNOLOGIES, AMERICAN MUSEUM OF NATURAL HISTORY; ARIZONA STATE UNIVERSITY; BIOLOGICAL RESEARCH CENTER AT HUNGARIAN ACADEMY OF SCIENCES; BRIGHAM AND WOMEN'S HOSPITAL, BOSTON; CALIFORNIA ACADEMY OF SCIENCES; CAPITAL MEDICAL UNIVERSITY CHINA; CENTRO DE REGULACION GENOMICA; CHILD AND FAMILY RESEARCH INSTITUTE, CANADA; CHINESE ACADEMY OF SCIENCES; CNRS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; COLD SPRING HARBOR LABORATORY; DALHOUSIE UNIVERSITY, NOVA SCOTIA; DANA-FARBER CANCER INSTITUTE; DOE JOINT GENOME INSTITUTE; EMORY UNIVERSITY; EUROPEAN BIOINFORMATICS INSTITUTE; EVOLVA BIOTECH A/S; FLANDERS INTERUNIVERSITY INSTITUTE FOR BIOTECHNOLOGY; HEBREW UNIVERSITY OF JERUSALEM; INDIANA UNIVERSITY; INDIANA UNIVERSITY SCHOOL OF MEDICINE INDIANAPOLIS; INSTITUCIO CATALANA DE RECERCA I ESTUDIS AVANCATS; INSTITUT MUNICIPAL D'INVESTIGACIO MEDICA; INSTITUTE OF SYSTEM BIOLOGY; JACKSON LABORATORY; JILIN UNIVERSITY; JUSTUS LIEBIG UNIVERSITY, GIESSEN; KAROLINSKA INSTITUTET; KAROLINSKA UNIVERSITY HOSPITAL; KUMAMOTO UNIVERSITY; LAWRENCE BERKELEY NATIONAL LABORATORY; LEIBNIZ INSTITUT FUR PFLANZENBIOCHEMIE; LIFE TECHNOLOGIES; LINKPINGS UNIVERSITT; LUNDS UNIVERSITET; MASSACHUSETTS INSTITUTE OF TECHNOLOGY; MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS; MCGILL UNIVERSITY; MONTANA STATE UNIVERSITY - BOZEMAN; NARA INSTITUTE OF SCIENCE AND TECHNOLOGY; NATIONAL CENTER FOR BIOTECHNOLOGY INFORMATION; NATIONAL INSTITUTES OF HEALTH, BETHESDA; NATIONAL UNIVERSITY OF SINGAPORE; NIJMEGEN CENTRE FOR MOLECULAR LIFE SCIENCES; NORTHWESTERN UNIVERSITY; OKLAHOMA MEDICAL RESEARCH FOUNDATION; OPEN UNIVERSITY; OREGON STATE UNIVERSITY; PEKING UNIVERSITY; PENNSYLVANIA STATE UNIVERSITY; PFIZER; ROCKEFELLER UNIVERSITY; SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE; SCRIPPS RESEARCH INSTITUTE; SEATTLE BIOMEDICAL RESEARCH INSTITUTE; SIMON FRASER UNIVERSITY; ST. LOUIS UNIVERSITY; STONY BROOK UNIVERSITY STATE UNIVERSITY OF NEW YORK; SWISS INSTITUTE OF BIOINFORMATICS; TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY; THE UNIVERSITY OF BRITISH COLUMBIA; THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL; TOHOKU UNIVERSITY; TOKYO METROPOLITAN UNIVERSITY; TSINGHUA UNIVERSITY; UNIVERSITY OF CALIFORNIA, BERKELEY, DAVIS, RIVERSIDE, SAN DIEGO AND SANTA CRUZ; UCL; UNIVERSIDADE DO PORTO; UNIVERSIT DEGLI STUDI DI NAPOLI FEDERICO II; UNIVERSITAT D'ALICANTE; UNIVERSITT FREIBURG IM BREISGAU; UNIVERSITT LAUSANNE SCHWEIZ; UNIVERSITAT ROVIRA I VIRGIL; UNIVERSITT TBINGEN; UNIVERSITT WIEN; UNIVERSITE CLAUDE BERNARD LYON; UNIVERSIT DE STRASBOURG; UNIVERSIT PARIS 7; UNIVERSIT PIERRE ET MARIE CURIE; UNIVERSITY MICHIGAN ANN ARBOR; UNIVERSITY OF ALABAMA AT BIRMINGHAM; UNIVERSITY OF ARIZONA; UNIVERSITY OF CALGARY; UNIVERSITY OF CHICAGO; UNIVERSITY OF CONNECTICUT HEALTH CENTER; UNIVERSITY OF DUNDEE; UNIVERSITY OF EDINBURGH; UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN; UNIVERSITY OF KENTUCKY; UNIVERSITY OF MANCHESTER; UNIVERSITY OF MISSOURI; UNIVERSITY OF NOTTINGHAM; UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER; UNIVERSITY OF OREGON; UNIVERSITY OF OXFORD; UNIVERSITY OF PENNSYLVANIA; UNIVERSITY OF PITTSBURGH; UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH; UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA; UNIVERSITY OF SOUTHERN CALIFORNIA; UNIVERSITY OF TORONTO; UNIVERSITY OF UTAH; UNIVERSITY OF WASHINGTON; UNIVERSITY OF WASHINGTON SEATTLE; UNIVERSITY OF WATERLOO; UNIVERZITA KARLOVA V PRAZE; WASHINGTON UNIVERSITY; YONSEI UNIVERSITY; ZHEJIANG UNIVERSITY.
FORM 990, PART III, LINE 4 CONT.	INDEPENDENT RESEARCH PROGRAM LEADERS	LABORATORIES INDIVIDUAL SCIENTISTS AT THE STOWERS INSTITUTE SPECIALIZE IN THE STUDY OF ONE OR MORE PARTICULAR GENES, EACH OF WHICH MAY CAUSE OR HAVE INFLUENCE IN VARIOUS KINDS OF DISEASE. IN 2011, RENOWNED DEVELOPMENTAL BIOLOGIST TATJANA PIOTROWSKI, PH.D., AND TRAILBLAZING REGENERATION EXPERT ALEJANDRO SNCHEZ ALVARADO, PH.D. JOINED THE FACULTY OF STOWERS INSTITUTE FOR MEDICAL RESEARCH. A COMPREHENSIVE LIST OF RESEARCH LEADERS FOLLOWS: - ROBERT KRUMLAUF, PH.D., SCIENTIFIC DIRECTOR AND INVESTIGATOR, JOINED THE STOWERS INSTITUTE IN 2000 FROM ENGLAND'S NATIONAL INSTITUTE FOR MEDICAL RESEARCH, THE RIDGEWAY, MILL HILL, LONDON, WHERE HE WAS HEAD OF THE DIVISION OF DEVELOPMENTAL NEUROBIOLOGY. DR. KRUMLAUF RECEIVED A PH.D. IN DEVELOPMENTAL BIOLOGY FROM OHIO STATE UNIVERSITY. RESEARCH FOCUS: ANALYSIS OF MOLECULAR PATHWAYS THAT REGULATE HOW THE MAMMALIAN HEAD, BRAIN AND NERVOUS SYSTEM ARE BUILT, USING A VARIETY OF VERTEBRATE MODEL SYSTEMS - SUSAN ABMAYR, PH.D., ASSOCIATE INVESTIGATOR, JOINED THE STOWERS INSTITUTE IN 2003 FROM THE PENNSYLVANIA STATE UNIVERSITY WHERE SHE SERVED AS ASSOCIATE PROFESSOR OF MOLECULAR GENETICS. SHE EARNED A PH.D. IN BIOCHEMISTRY AND MOLECULAR BIOLOGY FROM THE ROCKEFELLER UNIVERSITY AND COMPLETED POSTDOCTORAL TRAINING IN THE DEPARTMENT OF BIOCHEMISTRY AND MOLECULAR BIOLOGY AT HARVARD UNIVERSITY UNDER THE DIRECTION OF PROFESSOR TOM MANIATIS. RESEARCH FOCUS: MOLECULAR GENETICS OF CELL FATE SPECIFICATION AND DIFFERENTIATION IN DROSOPHILA, USING THE EMBRYONIC DEVELOPMENT OF THE MUSCULATURE AS A MODEL SYSTEM - PETER BAUMANN, PH.D., ASSOCIATE INVESTIGATOR AND HOWARD HUGHES MEDICAL INSTITUTE EARLY CAREER SCIENTIST, JOINED THE STOWERS INSTITUTE IN 2002 AFTER COMPLETING A HOWARD HUGHES MEDICAL INSTITUTE POSTDOCTORAL FELLOWSHIP IN THE LABORATORY OF DR. THOMAS R. CECH AT THE UNIVERSITY OF COLORADO-BOULDER. DR. BAUMANN RECEIVED A PH.D. IN BIOCHEMISTRY FROM THE IMPERIAL CANCER RESEARCH FUND AND UNIVERSITY COLLEGE, LONDON. RESEARCH FOCUS: FUNCTIONAL ANALYSIS OF TELOMERES AND THEIR ROLES IN CELLULAR IMMORTALITY AND CANCER - MARCO BLANCHETTE, PH.D., ASSISTANT INVESTIGATOR, JOINED THE STOWERS INSTITUTE IN 2006 FROM A POSTDOCTORAL POSITION WITH DR. DONALD C. RIO AT THE UNIVERSITY OF CALIFORNIA-BERKELEY WHERE HE WAS RECIPIENT OF A HUMAN FRONTIER LONG-TERM FELLOWSHIP. DR. BLANCHETTE RECEIVED A PH.D. DEGREE IN MICROBIOLOGY FROM THE UNIVERSIT DE SHERBROOKE, CANADA. RESEARCH FOCUS: FUNCTIONAL GENOMIC ANALYSIS OF THE MECHANISMS CONTROLLING ALTERNATIVE PRE-MRNA SPLICING - JOAN CONAWAY, PH.D., INVESTIGATOR, JOINED THE STOWERS INSTITUTE IN 2001 FROM THE OKLAHOMA MEDICAL RESEARCH FOUNDATION WHERE SHE WAS AN ASSOCIATE INVESTIGATOR OF THE HOWARD HUGHES MEDICAL INSTITUTE AND INTERIM HEAD OF THE PROGRAM IN MOLECULAR AND CELL BIOLOGY. DR. CONAWAY RECEIVED HER DOCTORATE IN CELL BIOLOGY FROM STANFORD UNIVERSITY SCHOOL OF MEDICINE. RESEARCH FOCUS: ANALYSIS OF THE MOLECULAR MECHANISM AND REGULATION OF GENE TRANSCRIPTION - RONALD CONAWAY, PH.D., INVESTIGATOR, JOINED THE STOWERS INSTITUTE IN 2001 FROM THE OKLAHOMA MEDICAL RESEARCH FOUNDATION WHERE HE WAS HOLDER OF THE CHAPMAN CHAIR IN MEDICAL RESEARCH. DR. CONAWAY RECEIVED HIS PH.D. IN BIOCHEMISTRY FROM STANFORD UNIVERSITY SCHOOL OF MEDICINE. RESEARCH FOCUS: ANALYSIS OF THE MOLECULAR MECHANISM AND REGULATION OF GENE TRANSCRIPTION - JENNIFER GERTON, PH.D., ASSOCIATE INVESTIGATOR, JOINED THE STOWERS INSTITUTE IN 2002 FROM A POSTDOCTORAL FELLOWSHIP IN THE LABORATORY OF DR. JOSEPH DERISI IN THE DEPARTMENT OF BIOCHEMISTRY AND BIOPHYSICS AT THE UNIVERSITY OF CALIFORNIA-SAN FRANCISCO. DR. GERTON RECEIVED A PH.D. IN MICROBIOLOGY AND IMMUNOLOGY FROM STANFORD UNIVERSITY. RESEARCH FOCUS: GENOMIC AND GENETIC ANALYSIS OF CHROMOSOME SEGREGATION AND CHROMOSOME DYNAMICS - MATTHEW GIBSON, PH.D., ASSOCIATE INVESTIGATOR, JOINED THE STOWERS INSTITUTE IN 2006 FROM A JANE COFFIN CHILDS MEMORIAL FUND POSTDOCTORAL FELLOWSHIP WITH DR. NORBERT PERRIMON AT HARVARD MEDICAL SCHOOL. DR. GIBSON RECEIVED A PH.D. IN ZOOLOGY FROM THE UNIVERSITY OF WASHINGTON. RESEARCH FOCUS: GENETIC ANALYSIS OF MECHANISMS CONTROLLING SIGNAL TRANSDUCTION, CELL PROLIFERATION, AND EPITHELIAL MORPHOGENESIS DURING DROSOPHILA DEVELOPMENT - R. SCOTT HAWLEY, PH.D., INVESTIGATOR, JOINED THE STOWERS INSTITUTE IN 2001 FROM THE UNIVERSITY OF CALIFORNIA-DAVIS WHERE HE WAS A PROFESSOR OF GENETICS IN THE MOLECULAR AND CELLULAR BIOLOGY SECTION. DR. HAWLEY EARNED A PH.D. IN GENETICS FROM THE UNIVERSITY OF WASHINGTON AND COMPLETED POSTDOCTORAL TRAINING AS A HELEN HAY WHITNEY FELLOW AT THE INSTITUTE FOR CANCER RESEARCH IN PHILADELPHIA. RESEARCH FOCUS: INVESTIGATION OF MECHANISMS THAT INFLUENCE HOW CHROMOSOMES PAIR AND SEGREGATE DURING MEIOSIS USING DROSOPHILA AS AN EXPERIMENTAL SYSTEM - SUE JASPERSEN, PH.D., ASSISTANT INVESTIGATOR, JOINED THE STOWERS INSTITUTE IN 2005 FROM THE LABORATORY OF DR. MARK WINEY AT THE UNIVERSITY OF COLORADO-BOULDER WHERE SHE WAS A KECK FOUNDATION FELLOW, A HELEN HAY WHITNEY FELLOW, AND THE RECIPIENT OF A LEUKEMIA & LYMPHOMA SOCIETY CAREER DEVELOPMENT AWARD. DR. JASPERSEN HOLDS A PH.D. IN BIOCHEMISTRY FROM THE UNIVERSITY OF CALIFORNIA-SAN FRANCISCO. RESEARCH FOCUS: INNER NUCLEAR MEMBRANE PROTEIN LOCALIZATION AND ROLE IN CHROMOSOME POSITIONING AND SEGREGATION - LINHENG LI, PH.D., INVESTIGATOR, JOINED THE STOWERS INSTITUTE IN 2000 FROM THE UNIVERSITY OF WASHINGTON MEDICAL CENTER WHERE HE HELD A FACULTY APPOINTMENT AFTER COMPLETING POSTDOCTORAL TRAINING IN THE LABORATORY DIRECTED BY DR. LEROY HOOD. DR. LI EARNED HIS PH.D. IN MOLECULAR AND CELLULAR BIOLOGY FROM NEW YORK UNIVERSITY MEDICAL SCHOOL UNDER THE MENTORING OF DR. EDWARD ZIFF. RESEARCH FOCUS: INVESTIGATION OF MOLECULAR AND GENETIC PATHWAYS CONTROLLING ADULT STEM CELL DEVELOPMENT IN THE HEMATOPOIETIC AND INTESTINAL SYSTEMS USING TRANSGENIC AND GENE TARGETING ANIMAL MODEL APPROACHES
FORM 990, PART III, LINE 4 CONT.		- RONG LI, PH.D., INVESTIGATOR, JOINED THE STOWERS INSTITUTE IN 2005 FROM THE DEPARTMENT OF CELL BIOLOGY AT HARVARD MEDICAL SCHOOL WHERE SHE SERVED AS AN ASSOCIATE PROFESSOR. SHE EARNED A PH.D. IN CELL BIOLOGY AT THE UNIVERSITY OF CALIFORNIA-SAN FRANCISCO WITH DR. ANDREW MURRAY AND HELD A DAMON RUNYON-WALTER WINCHELL CANCER RESEARCH FELLOWSHIP AS A POSTDOCTORAL ASSOCIATE WITH DR. DAVID DRUBIN AT THE UNIVERSITY OF CALIFORNIA-BERKELEY. RESEARCH FOCUS: MECHANISM OF CELL POLARIZATION AND CELL MOTILITY, GENOME DYNAMICS AND CELLULAR EVOLVABILITY, AND EPITHELIAL TISSUE MORPHOGENESIS - HO YI MAK, PH.D., ASSISTANT INVESTIGATOR, JOINED THE STOWERS INSTITUTE IN 2006 FROM A HUMAN FRONTIER SCIENCE PROGRAM POSTDOCTORAL FELLOWSHIP IN THE LABORATORY OF DR. GARY RUVKUN AT HARVARD MEDICAL SCHOOL. DR. MAK RECEIVED A PH.D. IN MOLECULAR PATHOLOGY FROM THE IMPERIAL CANCER RESEARCH FUND AND UNIVERSITY COLLEGE, LONDON. RESEARCH FOCUS: ANALYSIS OF MOLECULAR PATHWAYS THAT REGULATE CELLULAR FAT STORAGE IN RESPONSE TO NUTRIENT AVAILABILITY AND LIPID METABOLISM - TATJANA PIOTROWSKI, PH.D. ASSOCIATE INVESTIGATOR, JOINED THE STOWERS INSTITUTE IN 2011 FROM THE UNIVERSITY OF UTAH'S SCHOOL OF MEDICINE, WHERE SHE WAS AN ASSOCIATE PROFESSOR IN THE DEPARTMENT OF NEUROBIOLOGY AND ANATOMY. SHE RECEIVED HER MASTER'S DEGREE FROM THE UNIVERSITY OF TBINGEN, GERMANY, AND HER DOCTORATE DEGREE FROM THE MAX PLANCK INSTITUTE FOR DEVELOPMENTAL BIOLOGY IN TBINGEN. RESEARCH FOCUS: COLLECTIVE CELL MIGRATION, CELL TYPE SPECIFICATION AND STEM CELL BIOLOGY IN ZEBRAFISH AS A MODEL SYSTEM. - ALEJANDRO SNCHEZ ALVARADO, PH.D., INVESTIGATOR, JOINED THE STOWERS INSTITUTE IN 2011 FROM THE UNIVERSITY OF UTAH'S SCHOOL OF MEDICINE, WHERE HE HELD THE H.A & EDNA BENNING PROFESSORSHIP OF NEUROBIOLOGY AND ANATOMY. HE RECEIVED A B.S. IN MOLECULAR BIOLOGY AND CHEMISTRY FROM VANDERBILT UNIVERSITY IN NASHVILLE, TENN., AND A PH.D. IN PHARMACOLOGY AND CELL BIOPHYSICS FROM THE UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE IN CINCINNATI, OHIO. RESEARCH FOCUS: THE MOLECULAR AND CELLULAR MECHANISMS UNDERPINNING ANIMAL REGENERATION USING THE PLANARIAN SCHMIDTEA MEDITERRANEA AS A MODEL SYSTEM - ALI SHILATIFARD, PH.D., INVESTIGATOR, JOINED THE STOWERS INSTITUTE IN 2007 FROM THE SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE WHERE HE WAS A PROFESSOR OF BIOCHEMISTRY AND ASSOCIATE DIRECTOR FOR BASIC SCIENCES AT THE SAINT LOUIS UNIVERSITY CANCER CENTER. DR. SHILATIFARD EARNED A PH.D. IN BIOCHEMISTRY FROM THE UNIVERSITY OF GEORGIA AND THE UNIVERSITY OF OKLAHOMA SCHOOL OF MEDICINE AND COMPLETED POSTDOCTORAL TRAINING AS A JANE COFFIN CHILDS FELLOW AT THE OKLAHOMA MEDICAL RESEARCH FOUNDATION. RESEARCH FOCUS: MOLECULAR PATHWAY OF LEUKEMOGENESIS - KAUSIK SI, PH.D., ASSOCIATE INVESTIGATOR, JOINED THE STOWERS INSTITUTE IN 2005 FROM THE LABORATORY OF DR. ERIC KANDEL AT COLUMBIA UNIVERSITY CENTER FOR NEUROBIOLOGY AND BEHAVIOR WHERE HE WAS A JANE COFFIN CHILDS FELLOW AND A FRANCIS GOELET FELLOW IN NEUROSCIENCE. DR. SI EARNED A PH.D. IN MOLECULAR BIOLOGY FROM THE ALBERT EINSTEIN COLLEGE OF MEDICINE. RESEARCH FOCUS: ROLE OF SYNAPTIC PROTEIN SYNTHESIS IN INFORMATION ACQUISITION AND MEMORY STORAGE - PAUL TRAINOR, PH.D., ASSOCIATE INVESTIGATOR, JOINED THE STOWERS INSTITUTE IN 2001 FROM A RESEARCH POSITION AT THE NATIONAL INSTITUTE FOR MEDICAL RESEARCH AT MILL HILL, LONDON, WHERE HE COMPLETED POSTDOCTORAL TRAINING. DR. TRAINOR HAS A PH.D. IN DEVELOPMENTAL BIOLOGY FROM CHILDREN'S MEDICAL RESEARCH INSTITUTE AT THE UNIVERSITY OF SYDNEY, AUSTRALIA. RESEARCH FOCUS: INVESTIGATION OF THE INTERACTIONS BETWEEN DISTINCT TISSUES IN THE BODY AND THEIR REGULATION DURING NORMAL DEVELOPMENT TO REVEAL PATHWAYS THAT REGULATE NORMAL CRANIAL AND FACIAL DEVELOPMENT - JERRY WORKMAN, PH.D., INVESTIGATOR, JOINED THE STOWERS INSTITUTE IN 2003 FROM THE PENNSYLVANIA STATE UNIVERSITY WHERE HE HELD THE PAUL BERG PROFESSORSHIP OF BIOCHEMISTRY AND WAS AN ASSOCIATE INVESTIGATOR OF THE HOWARD HUGHES MEDICAL INSTITUTE. DR. WORKMAN EARNED A PH.D. IN CELL AND MOLECULAR BIOLOGY FROM THE UNIVERSITY OF MICHIGAN AND COMPLETED POSTDOCTORAL TRAINING AT THE ROCKEFELLER UNIVERSITY WITH DR. BOB ROEDER. RESEARCH FOCUS: STUDY OF THE PROTEIN COMPLEXES THAT MODIFY CHROMATIN - TING XIE, PH.D., INVESTIGATOR, JOINED THE STOWERS INSTITUTE IN 2000 AFTER COMPLETING A HOWARD HUGHES MEDICAL INSTITUTE POSTDOCTORAL FELLOWSHIP IN THE LABORATORY OF DR. ALLAN C. SPRADLING AT THE CARNEGIE INSTITUTION OF WASHINGTON. DR. XIE RECEIVED HIS PH.D. FROM THE JOINT GRADUATE PROGRAM IN MOLECULAR BIOLOGY AND BIOCHEMISTRY OF RUTGERS UNIVERSITY AND THE UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY. RESEARCH FOCUS: GENETIC AND MOLECULAR ANALYSIS OF STEM CELLS AND GERM CELL DEVELOPMENT IN DROSOPHILA AND MOUSE - C. RON YU, PH.D., ASSOCIATE INVESTIGATOR, JOINED THE STOWERS INSTITUTE IN 2005 FROM THE LABORATORY OF DR. RICHARD AXEL AT COLUMBIA UNIVERSITY CENTER FOR NEUROBIOLOGY AND BEHAVIOR WHERE HE HELD A NATIONAL INSTITUTES OF HEALTH MENTORED RESEARCH SCIENTIST AWARD FROM THE NATIONAL INSTITUTE OF MENTAL HEALTH. DR. YU EARNED HIS PH.D. IN MOLECULAR, CELLULAR, AND BIOPHYSICAL STUDIES AT COLUMBIA UNIVERSITY. RESEARCH FOCUS: HOW OLFACTORY SENSORY INFORMATION IS DETECTED, INTEGRATED, AND PROCESSED IN THE BRAIN TO INFLUENCE SPECIFIC INNATE BEHAVIORS - JULIA ZEITLINGER, PH.D., ASSISTANT INVESTIGATOR, JOINED THE STOWERS INSTITUTE IN 2007 FROM THE LAB OF DR. RICHARD YOUNG AT THE WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH AT MASSACHUSETTS INSTITUTE OF TECHNOLOGY WHERE SHE WAS THE RECIPIENT OF A LONG-TERM POSTDOCTORAL FELLOWSHIP FROM THE HUMAN FRONTIER SCIENCE PROGRAM. DR. ZEITLINGER EARNED A PH.D. IN MOLECULAR BIOLOGY FROM THE EUROPEAN MOLECULAR BIOLOGY LABORATORY IN HEIDELBERG, GERMANY. RESEARCH FOCUS: ANALYSIS OF THE GENE REGULATORY NETWORKS UNDERLYING CELLULAR DIFFERENTIATION
FORM 990, PART III, LINE 4 CONT.		TECHNOLOGY CENTERS - PAUL KULESA, PH.D., DIRECTOR OF IMAGING, JOINED THE STOWERS INSTITUTE IN 2002 AFTER COMPLETING A BURROUGHS WELLCOME FUND POSTDOCTORAL FELLOWSHIP IN THE LABORATORY OF DR. SCOTT E. FRASER AT THE CALIFORNIA INSTITUTE OF TECHNOLOGY. DR. KULESA RECEIVED A PH.D. IN APPLIED MATHEMATICS UNDER DR. J.D. MURRAY AT THE UNIVERSITY OF WASHINGTON. RESEARCH FOCUS: CELL MIGRATION IN DEVELOPMENT AND CANCER - ARCADY MUSHEGIAN, PH.D., DIRECTOR OF BIOINFORMATICS RESEARCH, JOINED THE STOWERS INSTITUTE IN 2001 FROM AKKADIX CORPORATION IN SAN DIEGO WHERE HE LED THE BIOINFORMATICS PROGRAM. DR. MUSHEGIAN EARNED A DOCTORATE IN MOLECULAR BIOLOGY AT MOSCOW STATE UNIVERSITY AND RECEIVED TRAINING AT THE UNIVERSITY OF KENTUCKY, UNIVERSITY OF WASHINGTON, AND WITH DR. EUGENE KOONIN AT THE NATIONAL CENTER FOR BIOTECHNOLOGY INFORMATION AT THE U.S. NATIONAL INSTITUTES OF HEALTH. RESEARCH FOCUS: COMPUTATIONAL ANALYSIS OF GENES AND PROTEINS - MICHAEL WASHBURN, PH.D., DIRECTOR OF PROTEOMICS, JOINED THE STOWERS INSTITUTE IN 2003 FROM THE TORREY MESA RESEARCH INSTITUTE IN SAN DIEGO WHERE HE WAS A SENIOR STAFF SCIENTIST IN PROTEOMICS. HE EARNED A PH.D. IN BIOCHEMISTRY AND ENVIRONMENTAL TOXICOLOGY FROM MICHIGAN STATE UNIVERSITY BEFORE COMPLETING A POSTDOCTORAL FELLOWSHIP WITH PROFESSOR JOHN YATES, III IN THE DEPARTMENT OF MOLECULAR BIOTECHNOLOGY AT THE UNIVERSITY OF WASHINGTON. RESEARCH FOCUS: QUANTITATIVE PROTEOMICS AND PROTEIN COMPLEX DYNAMICS
HOURS DEVOTED FOR RELATED ORGANIZATION	FORM 990 PART VII	NAME:JAMES E. STOWERS JR. TITLE:DIRECTOR HOURS:4
HOURS DEVOTED FOR RELATED ORGANIZATION	FORM 990 PART VII	NAME:DAVID A. WELTE TITLE:DIRECTOR/SECRETARY HOURS:46
HOURS DEVOTED FOR RELATED ORGANIZATION	FORM 990 PART VII	NAME:RODERICK L. STURGEON TITLE:DIRECTOR HOURS:48
HOURS DEVOTED FOR RELATED ORGANIZATION	FORM 990 PART VII	NAME:WILLIAM B. NEAVES TITLE:DIRECTOR/PRESIDENT EMERITUS HOURS:6
HOURS DEVOTED FOR RELATED ORGANIZATION	FORM 990 PART VII	NAME:DAVID M. CHAO TITLE:DIRECTOR/PRESIDENT/CEO HOURS:4
HOURS DEVOTED FOR RELATED ORGANIZATION	FORM 990 PART VII	NAME:RICHARD W. BROWN TITLE:DIRECTOR/CHAIR HOURS:48
HOURS DEVOTED FOR RELATED ORGANIZATION	FORM 990 PART VII	NAME:ROBERT E. KRUMLAUF TITLE:SCIENTIFIC DIRECTOR HOURS:2

For Paperwork Reduction Act Notice, see the Instructions for Form 990 or 990-EZ.

Cat. No. 51056K

Schedule O (Form 990 or 990-EZ) 2011

Additional Data

Software ID:
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- TIN:

SCHEDULE R
(Form 990)

Department of the Treasury
Internal Revenue Service

Related Organizations and Unrelated Partnerships

Complete if the organization answered "Yes" to Form 990, Part IV, line 33, 34, 35, 36, or 37.
MediumBullet

Attach to Form 990. MediumBullet

See separate instructions.

OMB No. 1545-0047

2011

Open to Public Inspection

Name of the organization

STOWERS INSTITUTE FOR MEDICAL RESEARCH

Employer identification number

20-2993509

Part I

Identification of Disregarded Entities (Complete if the organization answered "Yes" on Form 990, Part IV, line 33.)

(a) Name, address, and EIN of disregarded entity	(b) Primary activity	(c) Legal domicile (state or foreign country)	(d) Total income	(e) End-of-year assets	(f) Direct controlling entity

Part II

Identification of Related Tax-Exempt Organizations (Complete if the organization answered "Yes" on Form 990, Part IV, line 34 because it had one or more related tax-exempt organizations during the tax year.)

(a) Name, address, and EIN of related organization	(b) Primary activity	(c) Legal domicile (state or foreign country)	(d) Exempt Code section	(e) Public charity status (if section 501(c)(3))	(f) Direct controlling entity	(g) Section 512(b)(13) controlled organization
(a) Name, address, and EIN of related organization	(b) Primary activity	(c) Legal domicile (state or foreign country)	(d) Exempt Code section	(e) Public charity status (if section 501(c)(3))	(f) Direct controlling entity	Yes	No
(1) STOWERS SCIENTIFIC EDUCATION INSTITUTE 1000 EAST 50TH STREET KANSAS CITY,MO64110 20-5916445	SUPPORT ORG	DE	501(C)(3)	11A-TYPE I	SIMR	Yes
(2) STOWERS RESOURCE MANAGEMENTINC 1000 EAST 50TH STREET KANSAS CITY,MO64110 41-2186719	SUPPORT ORG	DE	501(C)(3)	11A-TYPE I	SIMR	Yes
(3) BIOMED VALLEY CORPORATION 1000 EAST 50TH STREET KANSAS CITY,MO64110 74-3238244	SUPPORT ORG	DE	501(C)(3)	11A-TYPE I	SIMR	Yes
(4) STOWERS REAL ESTATE HOLDING CORPORATION 1000 EAST 50TH STREET KANSAS CITY,MO64110 26-1472230	TITLE HOLDING	DE	501(C)(2)	N/A	SRM		No
(5) THE GRADUATE SCHOOL OF SIMR 1000 EAST 50TH STREET KANSAS CITY,MO64110 27-4482762	EDUCATION	DE	501(C)(3)	2	SIMR	Yes
(6) STOWERS POLICY INSTITUTE INC 100O EAST 50TH STREET KANSAS CITY,MO64110 20-3270502	SEE PART VII	DE	501(C)(4)	N/A	SIMR	Yes

For Privacy Act and Paperwork Reduction Act Notice, see the Instructions for Form 990.

Cat. No. 50135Y

Schedule R (Form 990) 2011

Page 2

Part III

Identification of Related Organizations Taxable as a Partnership (Complete if the organization answered "Yes" on Form 990, Part IV, line 34 because it had one or more related organizations treated as a partnership during the tax year.)

(a) Name, address, and EIN of related organization	(b) Primary activity	(c) Legal domicile (state or foreign country)	(d) Direct controlling entity	(f) Share of total income	(g) Share of end-of-year assets	(h) Disproprtionate allocations?		(i) Code VUBI amount in box 20 of Schedule K-1 (Form 1065)	(j) General or managing partner?
(a) Name, address, and EIN of related organization	(b) Primary activity	(c) Legal domicile (state or foreign country)	(d) Direct controlling entity	(f) Share of total income	(g) Share of end-of-year assets	Yes	No	(i) Code VUBI amount in box 20 of Schedule K-1 (Form 1065)	Yes	No

Part IV

Identification of Related Organizations Taxable as a Corporation or Trust (Complete if the organization answered "Yes" on Form 990, Part IV, line 34 because it had one or more related organizations treated as a corporation or trust during the tax year.)

(a) Name, address, and EIN of related organization	(b) Primary activity	(c) Legal domicile (state or foreign country)	(d) Direct controlling entity	(e) Type of entity (C corp, S corp, or trust)	(f) Share of total income	(g) Share of end-of-year assets	(h) Percentage ownership
(1) BIOMED VALLEY DISCOVERIESINC 4520 MAIN ST SUITE 1650 KANSAS CITY,MO64111 06-1646533	SEE PART VII	DE	BVC	C CORP	0	0	0 %

Schedule R (Form 990) 2011

Page 3

Part V

Transactions With Related Organizations (Complete if the organization answered "Yes" on Form 990, Part IV, line 34, 35, 35A, or 36.)

Note. Complete line 1 if any entity is listed in Parts II, III or IV.

Yes

1 During the tax year, did the orgranization engage in any of the following transactions with one or more related organizations listed in Parts II-IV?

a Receipt of (i) interest (ii) annuities (iii) royalties (iv) rent from a controlled entity . . . . . . . . . . . . . . . . . . . . . . .

Yes

b Gift, grant, or capital contribution to related organization(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

c Gift, grant, or capital contribution from related organization(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Yes

d Loans or loan guarantees to or for related organization(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

e Loans or loan guarantees by related organization(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

f Sale of assets to related organization(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

g Purchase of assets from related organization(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

h Exchange of assets with related organization(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

i Lease of facilities, equipment, or other assets to related organization(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . .

j Lease of facilities, equipment, or other assets from related organization(s) . . . . . . . . . . . . . . . . . . . . . . . . . . .

Yes

k Performance of services or membership or fundraising solicitations for related organization(s) . . . . . . . . . . . . . . . . . . . .

l Performance of services or membership or fundraising solicitations by related organization(s) . . . . . . . . . . . . . . . . . . . .

m Sharing of facilities, equipment, mailing lists, or other assets with related organization(s) . . . . . . . . . . . . . . . . . . . . .

Yes

n Sharing of paid employees with related organization(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Yes

o Reimbursement paid to related organization(s) for expenses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Yes

p Reimbursement paid by related organization(s) for expenses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Yes

q Other transfer of cash or property to related organization(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

r Other transfer of cash or property from related organization(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

If the answer to any of the above is "Yes," see the instructions for information on who must complete this line, including covered relationships and transaction thresholds.

(a) Name of other organization	(b) Transaction type(a-r)	(c) Amount involved	(d) Method of determining amount involved
(1) BIOMED VALLEY DISCOVERIES INC	A	347,249	MARKET VALUE
(2) BIOMED VALLEY DISCOVERIES INC	A	10,014	MARKET VALUE
(3) STOWERS SCIENTIFIC EDUCATION INSTITUTE	C	164,411	COST REIMB.
(4) BIOMED VALLEY CORPORATION	C	56,319	MARKET VALUE
(5) STOWERS RESOURCE MANAGEMENT INC	C	49,507,601	MARKET VALUE
(6) STOWERS REAL ESTATE HOLDING CORP	J	2,230,551	MARKET VALUE
(7) STOWERS RESOURCE MANAGEMENT INC	O	16,876,712	COST REIMB.
(8) BIOMED VALLEY DISCOVERIES INC	P	194,616	COST REIMB.
(9) SEE PART VII FOR ADDITIONAL INFORMATION

Schedule R (Form 990) 2011

Page 4

Part VI

Unrelated Organizations Taxable as a Partnership (Complete if the organization answered "Yes" on Form 990, Part IV, line 37.)

Provide the following information for each entity taxed as a partnership through which the organization conducted more than five percent of its activities (measured by total assets or gross revenue) that was not a related organization. See instructions regarding exclusion for certain investment partnerships.

(a) Name, address, and EIN of entity	(b) Primary activity	(c) Legal domicile (state or foreign country)	(e) Are all partners section 501(c)(3) organizations?		(f) Share of total income	(g) Share of end-of-year assets	(h) Disproprtionate allocations?		(i) Code VUBI amount in box 20 of Schedule K-1 (Form 1065)	(j) General or managing partner?
(a) Name, address, and EIN of entity	(b) Primary activity	(c) Legal domicile (state or foreign country)	Yes	No	(f) Share of total income	(g) Share of end-of-year assets	Yes	No	(i) Code VUBI amount in box 20 of Schedule K-1 (Form 1065)	Yes	No

Schedule R (Form 990) 2011

Page 5

Part VII

Supplemental Information

Complete this part to provide additional information for responses to questions on Schedule R (see instructions).

Identifier	Return Reference	Explanation
PART II, LINE 5, COLUMN B:		STOWERS POLICY INSTITUTE INC. ("SPI") IS AN ADVOCATE FOR A POLITICAL, ECONOMIC, AND SOCIAL ENVIRONMENT THAT ADVANCES AND PROTECTS BIOMEDICAL RESEARCH AND CURES. PART IV, COLUMN B: BIOMED VALLEY DISCOVERIES, INC.'S ("BVD") PRIMARY ACTIVITY IS DEVELOPMENT AND MARKETING OF SCIENTIFIC DISCOVERIES. BIOMED VALLEY CORPORATION IS THE 100% SHAREHOLDER OF BVD.
PART V, LINE 2 (1):		SIMR RECEIVES ROYALTY PAYMENTS FROM BVD PURSUANT TO A LICENSED TECHONOLOGY AGREEMENT DATED JANUARY 29, 2006. THESE ROYALTY PAYMENTS DO NOT CONSTITUTE GROSS INCOME DERIVED FROM AN UNRELATED TRADE OR BUSINESS UNDER SECTION 512(B)(13). THE ROYALTY PAYMENTS FROM BVD TO SIMR DO NOT REDUCE BVD'S TAXABLE INCOME, WHICH WOULD HAVE BEEN UNRELATED BUSINESS TAXABLE INCOME IF BVD WERE EXEMPT UNDER SECTION 501(C)(3) AND HAD THE SAME EXEMPT PURPOSES AS SIMR. IN ADDITION, THE SPECIAL RULE UNDER 512(B)(13)(E) APPLIES.
PART V, LINE 2 (2):		SIMR RECEIVED PAYMENTS FROM BVD IN RETURN FOR A TEMPORARY USE OF SPACE.
PART V, LINE 2 (3):		SSEI PROVIDED FINANCIAL SUPPORT TO SIMR TO BE USED BY SIMR IN FURTHERANCE OF SIMR'S EXEMPT PURPOSE OF CONDUCTING MEDICAL RESEARCH AND SCIENCE EDUCATION ACTIVITIES.
PART V, LINE 2 (4):		BVC PROVIDED FINANCIAL SUPPORT TO SIMR TO BE USED BY SIMR IN FURTHERANCE OF SIMR'S EXEMPT PURPOSE OF CONDUCTING MEDICAL RESEARCH.
PART V, LINE 2 (5):		SRM PROVIDED FINANCIAL SUPPORT TO SIMR TO BE USED BY SIMR IN FURTHERANCE OF SIMR'S EXEMPT PURPOSE OF CONDUCTING MEDICAL RESEARCH.
PART V, LINE 2 (6):		IN MARCH 2009, SIMR ENTERED INTO A LEASE FOR A 280,000 SQUARE FEET BUILDING WITH STOWERS REAL ESTATE HOLDING CORPORATION ("SREHC"), A 501(C)(2) TAX EXEMPT ORGANIZATION THAT IS A RELATED PARTY OF SIMR. SIMR'S LEASE PAYMENTS TO SREHC IN 2011 TOTALED $2,230,551.
PART V, LINE 2 (7):		SIMR REIMBURSED SRM FOR COSTS ASSOCIATED WITH SRM'S ADMINISTRATIVE AND SUPPORT SERVICES PROVIDED TO SIMR. SRM IS A SUPPORTING ORGANIZATION TO SIMR.
PART V, LINE 2 (8):		SIMR WAS REIMBURSED BY BVD FOR ADMINISTRATIVE AND LOW MARGIN COVERED SERVICES USING THE SERVICE COST METHOD.
PART V, LINE 2 (9):		ALL OTHER TRANSACTIONS FOR LINE 1 WERE BETWEEN RELATED 501(C)(3) PUBLIC CHARITIES AND BELOW REPORTING THRESHOLDS.

Additional Data

Software ID:
Software Version:

1	Briefly describe the organization’s mission or most significant activities: STOWERS INSTITUTE FOR MEDICAL RESEARCH ("SIMR")EXEMPT PURPOSE IS TO PERFORM MEDICAL RESEARCH IN THE PUBLIC INTEREST WITH THE GOAL OF EXPANDING OUR UNDERSTANDING OF FUNDAMENTAL PROCESSES OF LIVING CELLS.
2	Check this box
3	Number of voting members of the governing body (Part VI, line 1a).....	3	7
4	Number of independent voting members of the governing body (Part VI, line 1b) ....	4	0
5	Total number of individuals employed in calendar year 2011 (Part V, line 2a) ...	5	401
6	Total number of volunteers (estimate if necessary) ....	6	2
7a	Total unrelated business revenue from Part VIII, column (C), line 12 ..	7a	0
b	Net unrelated business taxable income from Form 990-T, line 34 ..	7b	0

		Prior Year	Current Year
8	Contributions and grants (Part VIII, line 1h) .........	8,065,484	57,865,166
9	Program service revenue (Part VIII, line 2g) .........	73,404	182,210
10	Investment income (Part VIII, column (A), lines 3, 4, and 7d ) ....	2,874,441	1,897,001
11	Other revenue (Part VIII, column (A), lines 5, 6d, 8c, 9c, 10c, and 11e)	3,391,202	616,981
12	Total revenue—add lines 8 through 11 (must equal Part VIII, column (A), line 12)...................	14,404,531	60,561,358
13	Grants and similar amounts paid (Part IX, column (A), lines 1–3 )...	1,372,750	1,151,122
14	Benefits paid to or for members (Part IX, column (A), line 4).....	0	0
15	Salaries, other compensation, employee benefits (Part IX, column (A), lines 5–10)	26,301,376	28,620,114
16a	Professional fundraising fees (Part IX, column (A), line 11e).....	0	0
b	Total fundraising expenses (Part IX, column (D), line 25) 0
17	Other expenses (Part IX, column (A), lines 11a–11d, 11f–24f)....	45,019,071	42,289,039
18	Total expenses. Add lines 13–17 (must equal Part IX, column (A), line 25)	72,693,197	72,060,275
19	Revenue less expenses. Subtract line 18 from line 12.......	-58,288,666	-11,498,917
		Beginning of Current Year	End of Year
20	Total assets (Part X, line 16).............	496,643,745	475,896,618
21	Total liabilities (Part X, line 26).............	217,464,815	209,682,708
22	Net assets or fund balances. Subtract line 21 from line 20.....	279,178,930	266,213,910

Sign Here

	Signature of officer	Date

	Type or print name and title.


4a	(Code: ) (Expenses $ 64,911,315 including grants of $ 1,151,122 ) (Revenue $ 182,210 )
	SIMR'S ACCOMPLISHMENTS ARE DESCRIBED IN SCHEDULE O.

4b	(Code: ) (Expenses $ including grants of $ ) (Revenue $ )












4c	(Code: ) (Expenses $ including grants of $ ) (Revenue $ )












4d	Other program services (Describe in Schedule O.)
	(Expenses $ including grants of $ ) (Revenue $ )
4e	Total program service expenses$ 64,911,315

(A) Name and Title	(B) Average hours per week (describe hours for related organizations in Schedule O)	(C) Position (do not check more than one box, unless person is both an officer and a director/trustee)				(D) Reportable compensation from the organization (W- 2/1099-MISC)	(E) Reportable compensation from related organizations (W- 2/1099-MISC)	(F) Estimated amount of other compensation from the organization and related organizations
(A) Name and Title
(1) JAMES E STOWERS JR DIRECTOR	2.0	X				0	0	0
(2) VIRGINIA G STOWERS DIRECTOR	2.0	X				0	0	0
(3) DAVID A WELTE DIRECTOR/SECRETARY	2.0	X	X			0	977,117	55,297
(4) RODERICK L STURGEON DIRECTOR	2.0	X				0	1,157,859	51,962
(5) WILLIAM B NEAVES DIRECTOR/PRESIDENT EMERITUS	40.0	X	X			447,761	0	49,102
(6) DAVID M CHAO DIRECTOR/PRESIDENT/CEO	40.0	X	X			1,142,746	0	38,170
(7) RICHARD W BROWN DIRECTOR/CHAIR	2.0	X	X			0	1,732,640	48,262
(8) ROBERT E KRUMLAUF SCIENTIFIC DIRECTOR	40.0			X		449,339	0	51,549
(9) RONALD C CONAWAY INVESTIGATOR	40.0				X	251,805	0	38,169
(10) JOAN W CONAWAY INVESTIGATOR	40.0				X	249,652	0	49,552
(11) JERRY L WORKMAN INVESTIGATOR	40.0				X	250,131	0	43,910
(12) R SCOTT HAWLEY INVESTIGATOR	40.0				X	270,407	0	56,890
(13) ALI SHILATIFARD INVESTIGATOR	40.0				X	241,767	0	52,470

1b	Sub-Total................
c	Total from continuation sheets to Part VII, Section A....
d	Total (add lines 1b and 1c)............	3,303,608	3,867,616	535,333

(A) Name and business address	(B) Description of services	(C) Compensation
AMERICAN CENTURY INVESTMENTS 4500 MAIN STREET KANSAS CITY,MO64111	SEE SCH L, PART V	500,000




2 Total number of independent contractors (including but not limited to those listed above) who received more than $100,000 of compensation from the organization 1

				(A) Total revenue	(B) Related or exempt function revenue	(C) Unrelated business revenue	(D) Revenue excluded from tax under sections 512, 513, or 514
1a	Federated campaigns..1a
b	Membership dues....1b
c	Fundraising events....1c
d	Related organizations...1d		49,733,348
e	Government grants (contributions)1e		6,267,013

f	All other contributions, gifts, grants, and similar amounts not included above1f		1,864,805
g	Noncash contributions included in lines 1a-1f:$ 49,906,628
h	Total. Add lines 1a-1f.......			57,865,166
			Business Code
2a	COLLABORATION FEE FROM HHMI 501(C)(3)		900,099	182,210	182,210
b
c
d
e
f	All other program service revenue .
g	Total. Add lines 2a–2f........			182,210
3	Investment income (including dividends, interest
	and other similar amounts).....			584,440			584,440
4	Income from investment of tax-exempt bond proceeds..			0
5	Royalties............			366,619			366,619
		(i) Real	(ii) Personal
6a	Gross rents	10,014
b	Less: rental expenses	10,014
c	Rental income or (loss)
d	Net rental income or (loss).......
		(i) Securities	(ii) Other
7a	Gross amount from sales of assets other than inventory	85,180,210	15,290
b	Less: cost or other basis and sales expenses	83,858,641	24,298
c	Gain or (loss)	1,321,569	-9,008
d	Net gain or (loss)..........			1,312,561			1,312,561
8a	Gross income from fundraising events (not including $ of contributions reported on line 1c). See Part IV, line 18 ...
	a
b	Less: direct expenses ...b
c	Net income or (loss) from fundraising events..			0
9a	Gross income from gaming activities. See Part IV, line 19 ...
	a
b	Less: direct expenses ...b
c	Net income or (loss) from gaming activities...			0
10a	Gross sales of inventory, less returns and allowances .
	a
b	Less: cost of goods sold ..b
c	Net income or (loss) from sales of inventory..			0
Miscellaneous Revenue			Business Code
11a	MO QUALITY JOBS REBATE		900,099	203,964			203,964
b	OTHER REBATES & REVENUE		900,099	46,398			46,398
c
d	All other revenue ....
e	Total. Add lines 11a–11d ......			250,362
12	Total revenue. See Instructions....			60,561,358	182,210		2,513,982


				(A) Beginning of year		(B) End of year
1	Cashnon-interest-bearing ..........			2,178,335	1	1,943,474
2	Savings and temporary cash investments .......			0	2	0
3	Pledges and grants receivable, net .........			804,237	3	697,175
4	Accounts receivable, net .........			0	4	0
5	Receivables from current and former officers, directors, trustees, key employees, and highest compensated employees. Complete Part II of
	Schedule L ..........			0	5	0
6	Receivables from other disqualified persons (as defined under section 4958(f)(1)) and persons described in section 4958(c)(3)(B). Complete Part II of
	Schedule L ..........			0	6	0
7	Notes and loans receivable, net .............			0	7	0
8	Inventories for sale or use ..............			349,600	8	349,600
9	Prepaid expenses and deferred charges ............			631,357	9	714,385
10a	Land, buildings, and equipment: cost or other basis. Complete Part VI of Schedule D	10a	313,812,169
b	Less: accumulated depreciation. .....	10b	131,463,800	189,268,370	10c	182,348,369
11	Investments—publicly traded securities ..........			91,159,672	11	86,566,796
12	Investments—other securities. See Part IV, line 11 ......			15,662	12	354,224
13	Investments—program-related. See Part IV, line 11 ..			0	13	0
14	Intangible assets .........			0	14	0
15	Other assets. See Part IV, line 11 ...........			212,236,512	15	202,922,595
16	Total assets. Add lines 1 through 15 (must equal line 34)...			496,643,745	16	475,896,618
17	Accounts payable and accrued expenses .			5,780,182	17	7,365,107
18	Grants payable ..........			0	18	0
19	Deferred revenue ..........			536,488	19	617,194
20	Tax-exempt bond liabilities ..........			0	20	0
21	Escrow or custodial account liability. Complete Part IV of Schedule D..			0	21	0
22	Payables to current and former officers, directors, trustees, key employees, highest compensated employees, and disqualified
	persons. Complete Part II of Schedule L..........			0	22	0
23	Secured mortgages and notes payable to unrelated third parties ..			0	23	0
24	Unsecured notes and loans payable to unrelated third parties ....			0	24	0
25	Other liabilities (including federal income tax, payables to related third parties, and other liabilities not included on lines 17-24). Complete Part X of Schedule D.....			211,148,145	25	201,700,407
26	Total liabilities. Add lines 17 through 25.....			217,464,815	26	209,682,708
	Organizations that follow SFAS 117, check here and complete lines 27 through 29, and lines 33 and 34.
27	Unrestricted net assets .....			279,178,930	27	266,213,910
28	Temporarily restricted net assets .....			0	28	0
29	Permanently restricted net assets .....			0	29	0
	Organizations that do not follow SFAS 117, check here and complete lines 30 through 34.
30	Capital stock or trust principal, or current funds .....				30
31	Paid-in or capital surplus, or land, building or equipment fund .....				31
32	Retained earnings, endowment, accumulated income, or other funds				32
33	Total net assets or fund balances .....			279,178,930	33	266,213,910
34	Total liabilities and net assets/fund balances .....			496,643,745	34	475,896,618