TY 2015 Form 990

(A) Name and Title	(B) Average hours per week (list any hours for related organizations below dotted line)	(C) Position (do not check more than one box, unless person is both an officer and a director/trustee)	(E) Reportable compensation from related organizations (W- 2/1099-MISC)
(1) Michael Bassoff...................................................................... President, TGen Foundation	24.0 ................. 16.0	X	X	484,032	21,077
(2) BENNETT DORRANCE...................................................................... Board Member/Chairman	1.0 ................. 1.0	X	X	0	0
(3) RICHARD J LEHMANN...................................................................... Board Member/Treasurer	1.0 ................. 0.0	X	X	0	0
(4) KEN KENDRICK...................................................................... BOARD MEMBER/SECRETARY	1.0 ................. 0.0	X	X	0	0
(5) Teresa Burleson...................................................................... BOARD MBR/ASST SEC/ASST treaS	1.0 ................. 39.0	X	X	547,980	55,384
(6) Karl Eller...................................................................... Board Member	1.0 ................. 0.0	X		0	0
(7) Phil Francis...................................................................... Board Member	1.0 ................. 0.0	X		0	0
(8) Diane Halle...................................................................... Board Member	1.0 ................. 0.0	X		0	0
(9) Carrie Hulburd...................................................................... Board Member	1.0 ................. 0.0	X		0	0
(10) MIKE INGRAM...................................................................... BOARD MEMBER	1.0 ................. 0.0	X		0	0
(11) Catherine Ivy...................................................................... Board Member	1.0 ................. 0.0	X		0	0
(12) F FRANCIS NAJAFI...................................................................... BOARD MEMBER	1.0 ................. 0.0	X		0	0
(13) WILLIAM J POST...................................................................... BOARD MEMBER	1.0 ................. 1.0	X		0	0
(14) J Danforth Quayle...................................................................... Board Member	1.0 ................. 0.0	X		0	0
(15) Troy Richards...................................................................... Board Member	1.0 ................. 0.0	X		0	0
(16) Ray Thurston...................................................................... Board Member	1.0 ................. 0.0	X		0	0
(17) Jeffrey M Trent PhD...................................................................... Board Member	1.0 ................. 39.0	X		999,967	220,796

- TIN:

SCHEDULE A
(Form 990 or 990EZ)

Department of the Treasury
Internal Revenue Service

Public Charity Status and Public Support

Complete if the organization is a section 501(c)(3) organization or a section 4947(a)(1) nonexempt charitable trust.
right arrow

Attach to Form 990 or Form 990-EZ.
right arrow

Information about Schedule A (Form 990 or 990-EZ) and its instructions is at www.irs.gov/form990.

OMB No. 1545-0047

2015

Open to Public
Inspection

Name of the organization

THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE
FOUNDATION

Employer identification number

33-1092191

Part I

Reason for Public Charity Status (All organizations must complete this part.) See instructions.

The organization is not a private foundation because it is: (For lines 1 through 11, check only one box.)

A church, convention of churches, or association of churches described in section 170(b)(1)(A)(i).

A school described in section 170(b)(1)(A)(ii). (Attach Schedule E (Form 990 or 990-EZ))

A hospital or a cooperative hospital service organization described in section 170(b)(1)(A)(iii).

A medical research organization operated in conjunction with a hospital described in section 170(b)(1)(A)(iii). Enter the hospital's name, city, and state:

An organization operated for the benefit of a college or university owned or operated by a governmental unit described in section 170(b)(1)(A)(iv). (Complete Part II.)

A federal, state, or local government or governmental unit described in section 170(b)(1)(A)(v).

An organization that normally receives a substantial part of its support from a governmental unit or from the general public described in section 170(b)(1)(A)(vi). (Complete Part II.)

A community trust described in section 170(b)(1)(A)(vi). (Complete Part II.)

An organization that normally receives: (1) more than 331/3% of its support from contributions, membership fees, and gross receipts from activities related to its exempt functions—subject to certain exceptions, and (2) no more than 331/3% of its support from gross investment income and unrelated business taxable income (less section 511 tax) from businesses acquired by the organization after June 30, 1975. See section 509(a)(2). (Complete Part III.)

An organization organized and operated exclusively to test for public safety. See section 509(a)(4).

An organization organized and operated exclusively for the benefit of, to perform the functions of, or to carry out the purposes of one or more publicly supported organizations described in section 509(a)(1) or section 509(a)(2). See section 509(a)(3). Check the box in lines 11a through 11d that describes the type of supporting organization and complete lines 11e, 11f, and 11g.

Type I. A supporting organization operated, supervised, or controlled by its supported organization(s), typically by giving the supported organization(s) the power to regularly appoint or elect a majority of the directors or trustees of the supporting organization. You must complete Part IV, Sections A and B.

Type II. A supporting organization supervised or controlled in connection with its supported organization(s), by having control or management of the supporting organization vested in the same persons that control or manage the supported organization(s). You must complete Part IV, Sections A and C.

Type III functionally integrated. A supporting organization operated in connection with, and functionally integrated with, its supported organization(s) (see instructions). You must complete Part IV, Sections A, D, and E.

Type III non-functionally integrated. A supporting organization operated in connection with its supported organization(s) that is not functionally integrated. The organization generally must satisfy a distribution requirement and an attentiveness requirement (see instructions). You must complete Part IV, Sections A and D, and Part V.

Check this box if the organization received a written determination from the IRS that it is a Type I, Type II, Type III functionally integrated, or Type III non-functionally integrated supporting organization.

Enter the number of supported organizations ..............

Provide the following information about the supported organization(s).

(i)Name of supported organization	(ii) EIN	(iv) Is the organization listed in your governing document?		(v) Amount of monetary support (see instructions)	(vi) Amount of other support (see instructions)
(i)Name of supported organization	(ii) EIN	Yes	No	(v) Amount of monetary support (see instructions)	(vi) Amount of other support (see instructions)


Total

For Paperwork Reduction Act Notice, see the Instructions for
Form 990 or 990-EZ.

Cat. No. 11285F

Schedule A (Form 990 or 990-EZ) 2015

Page 2

Part II

Support Schedule for Organizations Described in Sections 170(b)(1)(A)(iv) and 170(b)(1)(A)(vi)
(Complete only if you checked the box on line 5, 7, or 8 of Part I or if the organization failed to qualify under Part III. If the organization fails to qualify under the tests listed below, please complete Part III.)

Section A. Public Support

Calendar year (or fiscal year beginning in)		(a) 2011	(b) 2012	(c) 2013	(d) 2014	(e) 2015	(f) Total
1	Gifts, grants, contributions, and membership fees received. (Do not include any unusual grants.) ....	5,860,920	488,410	12,174,321	13,561,515	9,117,401	41,202,567
2	Tax revenues levied for the organization's benefit and either paid to or expended on its behalf.......						0
3	The value of services or facilities furnished by a governmental unit to the organization without charge..						0
4	Total. Add lines 1 through 3	5,860,920	488,410	12,174,321	13,561,515	9,117,401	41,202,567
5	The portion of total contributions by each person (other than a governmental unit or publicly supported organization) included on line 1 that exceeds 2% of the amount shown on line 11, column (f)..						8,404,446
6	Public support. Subtract line 5 from line 4.						32,798,121

Section B. Total Support

Calendar year (or fiscal year beginning in)		(a) 2011	(b) 2012	(c) 2013	(d) 2014	(e) 2015	(f) Total
7	Amounts from line 4..	5,860,920	488,410	12,174,321	13,561,515	9,117,401	41,202,567
8	Gross income from interest, dividends, payments received on securities loans, rents, royalties and income from similar sources...	20,879	1,740	947	1,004	1,005	25,575
9	Net income from unrelated business activities, whether or not the business is regularly carried on..						0
10	Other income. Do not include gain or loss from the sale of capital assets (Explain in Part VI.)..						0
11	Total support. Add lines 7 through 10.						41,228,142

Gross receipts from related activities, etc. (see instructions) ..................

469

First five years. If the Form 990 is for the organization's first, second, third, fourth, or fifth tax year as a section 501(c)(3) organization, check this box and stop here........................................ right arrow

Section C. Computation of Public Support Percentage

Public support percentage for 2015 (line 6, column (f) divided by line 11, column (f)) .........

79.553 %

Public support percentage for 2014 Schedule A, Part II, line 14 ...............

79.857 %

16a

33 1/3% support test—2015. If the organization did not check the box on line 13, and line 14 is 33 1/3% or more, check this box
and stop here. The organization qualifies as a publicly supported organization ....................... right arrow

33 1/3% support test—2014. If the organization did not check a box on line 13 or 16a, and line 15 is 33 1/3% or more, check this
box and stop here. The organization qualifies as a publicly supported organization ..................... right arrow

17a

10%-facts-and-circumstances test—2015. If the organization did not check a box on line 13, 16a, or 16b, and line 14
is 10% or more, and if the organization meets the facts-and-circumstances test, check this box and stop here. Explain
in Part VI how the organization meets the "facts-and-circumstances" test. The organization qualifies as a publicly supported
organization ..................................................... right arrow

10%-facts-and-circumstances test—2014. If the organization did not check a box on line 13, 16a, 16b, or 17a, and line
15 is 10% or more, and if the organization meets the "facts-and-circumstances" test, check this box and stop here.
Explain in Part VI how the organization meets the "facts-and-circumstances" test. The organization qualifies as a publicly
supported organization ................................................ right arrow

Private foundation. If the organization did not check a box on line 13, 16a, 16b, 17a, or 17b, check this box and see
instructions ..................................................... right arrow

Schedule A (Form 990 or 990-EZ) 2015

Page 3

Part III

Support Schedule for Organizations Described in Section 509(a)(2)
(Complete only if you checked the box on line 9 of Part I or if the organization failed to qualify under Part II. If the organization fails to qualify under the tests listed below, please complete Part II.)

Section A. Public Support

Calendar year (or fiscal year beginning in)		(a) 2011	(b) 2012	(c) 2013	(d) 2014	(e) 2015	(f) Total
1	Gifts, grants, contributions, and membership fees received. (Do not include any "unusual grants.") .
2	Gross receipts from admissions, merchandise sold or services performed, or facilities furnished in any activity that is related to the organization's tax-exempt purpose......
3	Gross receipts from activities that are not an unrelated trade or business under section 513...
4	Tax revenues levied for the organization's benefit and either paid to or expended on its behalf...
5	The value of services or facilities furnished by a governmental unit to the organization without charge..
6	Total. Add lines 1 through 5.
7a	Amounts included on lines 1, 2, and 3 received from disqualified persons...
b	Amounts included on lines 2 and 3 received from other than disqualified persons that exceed the greater of $5,000 or 1% of the amount on line 13 for the year.
c	Add lines 7a and 7b..
8	Public support. (Subtract line 7c from line 6.)

Section B. Total Support

Calendar year (or fiscal year beginning in)		(a) 2011	(b) 2012	(c) 2013	(d) 2014	(e) 2015	(f) Total
9	Amounts from line 6...
10a	Gross income from interest, dividends, payments received on securities loans, rents, royalties and income from similar sources..
b	Unrelated business taxable income (less section 511 taxes) from businesses acquired after June 30, 1975.
c	Add lines 10a and 10b.
11	Net income from unrelated business activities not included in line 10b, whether or not the business is regularly carried on.
12	Other income. Do not include gain or loss from the sale of capital assets (Explain in Part VI.) ..
13	Total support. (Add lines 9, 10c, 11, and 12.)..

First five years. If the Form 990 is for the organization's first, second, third, fourth, or fifth tax year as a section 501(c)(3) organization,
check this box and stop here............................................. right arrow

Section C. Computation of Public Support Percentage

Public support percentage for 2015 (line 8, column (f) divided by line 13, column (f)) .........

Public support percentage from 2014 Schedule A, Part III, line 15 ...............

Section D. Computation of Investment Income Percentage

Investment income percentage for 2015 (line 10c, column (f) divided by line 13, column (f)) ......

Investment income percentage from 2014 Schedule A, Part III, line 17 .............

19a

331/3% support tests—2015. If the organization did not check the box on line 14, and line 15 is more than 33 1/3%, and line 17 is not more than 33 1/3%, check this box and stop here. The organization qualifies as a publicly supported organization ....... right arrow

33 1/3% support tests—2014. If the organization did not check a box on line 14 or line 19a, and line 16 is more than 33 1/3% and line 18 is not more than 33 1/3%, check this box and stop here. The organization qualifies as a publicly supported organization .... right arrow

Private foundation. If the organization did not check a box on line 14, 19a, or 19b, check this box and see instructions .... right arrow

Schedule A (Form 990 or 990-EZ) 2015

Page 4

Part IV

Supporting Organizations

(Complete only if you checked a box on line 11 of Part I. If you checked 11a of Part I, complete Sections A and B. If you checked 11b of Part I, complete Sections A and C. If you checked 11c of Part I, complete Sections A, D, and E. If you checked 11d of Part I, complete Sections A and D, and complete Part V.)

Section A. All Supporting Organizations

Yes

Are all of the organization’s supported organizations listed by name in the organization’s governing documents?
If "No," describe in Part VI how the supported organizations are designated. If designated by class or purpose,
describe the designation. If historic and continuing relationship, explain.

Did the organization have any supported organization that does not have an IRS determination of status under section 509(a)(1) or (2)? If "Yes," explain in Part VI how the organization determined that the supported organization was described in section 509(a)(1) or (2).

Did the organization have a supported organization described in section 501(c)(4), (5), or (6)? If "Yes," answer (b) and (c) below.

Did the organization confirm that each supported organization qualified under section 501(c)(4), (5), or (6) and satisfied the public support tests under section 509(a)(2)? If "Yes," describe in Part VI when and how the organization made the determination.

Did the organization ensure that all support to such organizations was used exclusively for section 170(c)(2)(B) purposes? If "Yes," explain in Part VI what controls the organization put in place to ensure such use.

Was any supported organization not organized in the United States ("foreign supported organization")? If “Yes” and if you checked 11a or 11b in Part I, answer (b) and (c) below.

Did the organization have ultimate control and discretion in deciding whether to make grants to the foreign supported organization? If “Yes,” describe in Part VI how the organization had such control and discretion despite being controlled or supervised by or in connection with its supported organizations.

Did the organization support any foreign supported organization that does not have an IRS determination under sections 501(c)(3) and 509(a)(1) or (2)? If “Yes,” explain in Part VI what controls the organization used to ensure that all support to the foreign supported organization was used exclusively for section 170(c)(2)(B) purposes.

Did the organization add, substitute, or remove any supported organizations during the tax year? If “Yes,” answer (b) and (c) below (if applicable). Also, provide detail in Part VI, including (i) the names and EIN numbers of the supported organizations added, substituted, or removed; (ii) the reasons for each such action; (iii) the authority under the organization's organizing document authorizing such action; and (iv) how the action was accomplished (such as by amendment to the organizing document).

Type I or Type II only. Was any added or substituted supported organization part of a class already designated in the organization's organizing document?

Substitutions only. Was the substitution the result of an event beyond the organization's control?

Did the organization provide support (whether in the form of grants or the provision of services or facilities) to anyone other than (i) its supported organizations, (ii) individuals that are part of the charitable class benefited by one or more of its supported organizations, or (iii) other supporting organizations that also support or benefit one or more of the filing organization’s supported organizations? If “Yes,” provide detail in Part VI.

Did the organization provide a grant, loan, compensation, or other similar payment to a substantial contributor (defined in section 4958(c)(3)(C)), a family member of a substantial contributor, or a 35% controlled entity with regard to a substantial contributor? If “Yes,” complete Part I of Schedule L (Form 990 or 990-EZ) .

Did the organization make a loan to a disqualified person (as defined in section 4958) not described in line 7? If “Yes,” complete Part I of Schedule L (Form 990 or 990-EZ).

Was the organization controlled directly or indirectly at any time during the tax year by one or more disqualified persons as defined in section 4946 (other than foundation managers and organizations described in section 509(a)(1) or (2))? If “Yes,” provide detail in Part VI.

Did one or more disqualified persons (as defined in line 9a) hold a controlling interest in any entity in which the supporting organization had an interest? If “Yes,” provide detail in Part VI.

Did a disqualified person (as defined in line 9a) have an ownership interest in, or derive any personal benefit from, assets in which the supporting organization also had an interest? If “Yes,” provide detail in Part VI.

10a

Was the organization subject to the excess business holdings rules of section 4943 because of section 4943(f) (regarding certain Type II supporting organizations, and all Type III non-functionally integrated supporting organizations)? If “Yes,” answer line 10b below.

10a

Did the organization have any excess business holdings in the tax year? (Use Schedule C, Form 4720, to determine whether the organization had excess business holdings).

10b

Schedule A (Form 990 or 990-EZ) 2015

Page 5

Part IV

Supporting Organizations (continued)

Yes

Has the organization accepted a gift or contribution from any of the following persons?

A person who directly or indirectly controls, either alone or together with persons described in (b) and (c) below, the governing body of a supported organization?

11a

A family member of a person described in (a) above?

11b

A 35% controlled entity of a person described in (a) or (b) above? If “Yes” to a, b, or c, provide detail in Part VI.

11c

Section B. Type I Supporting Organizations

Yes

Did the directors, trustees, or membership of one or more supported organizations have the power to regularly appoint or elect at least a majority of the organization’s directors or trustees at all times during the tax year? If “No,” describe in Part VI how the supported organization(s) effectively operated, supervised, or controlled the organization’s activities. If the organization had more than one supported organization, describe how the powers to appoint and/or remove directors or trustees were allocated among the supported organizations and what conditions or restrictions, if any, applied to such powers during the tax year.

Did the organization operate for the benefit of any supported organization other than the supported organization(s) that operated, supervised, or controlled the supporting organization? If “Yes,” explain in Part VI how providing such benefit carried out the purposes of the supported organization(s) that operated, supervised or controlled the supporting organization.

Section C. Type II Supporting Organizations

Yes

Were a majority of the organization’s directors or trustees during the tax year also a majority of the directors or trustees of each of the organization’s supported organization(s)? If “No,” describe in Part VI how control or management of the supporting organization was vested in the same persons that controlled or managed the supported organization(s).

Section D. All Type III Supporting Organizations

Yes

Did the organization provide to each of its supported organizations, by the last day of the fifth month of the organization’s tax year, (i) a written notice describing the type and amount of support provided during the prior tax year, (ii) a copy of the Form 990 that was most recently filed as of the date of notification, and (iii) copies of the organization’s governing documents in effect on the date of notification, to the extent not previously provided?

Were any of the organization’s officers, directors, or trustees either (i) appointed or elected by the supported organization(s) or (ii) serving on the governing body of a supported organization? If "No," explain in Part VI how the organization maintained a close and continuous working relationship with the supported organization(s).

By reason of the relationship described in (2), did the organization’s supported organizations have a significant voice in the organization’s investment policies and in directing the use of the organization’s income or assets at all times during the tax year? If "Yes," describe in Part VI the role the organization’s supported organizations played in this regard.

Section E. Type III Functionally-Integrated Supporting Organizations

Check the box next to the method that the organization used to satisfy the Integral Part Test during the year (see instructions):

The organization satisfied the Activities Test. Complete line 2 below.

The organization is the parent of each of its supported organizations. Complete line 3 below.

The organization supported a governmental entity. Describe in Part VI how you supported a government entity (see instructions)

Activities Test. Answer (a) and (b) below.

Yes

Did substantially all of the organization’s activities during the tax year directly further the exempt purposes of the supported organization(s) to which the organization was responsive? If "Yes," then in Part VI identify those supported organizations and explain how these activities directly furthered their exempt purposes, how the organization was responsive to those supported organizations, and how the organization determined that these activities constituted substantially all of its activities.

Did the activities described in (a) constitute activities that, but for the organization’s involvement, one or more of the organization’s supported organization(s) would have been engaged in? If "Yes," explain in Part VI the reasons for the organization’s position that its supported organization(s) would have engaged in these activities but for the organization’s involvement.

Parent of Supported Organizations. Answer (a) and (b) below.

Did the organization have the power to regularly appoint or elect a majority of the officers, directors, or trustees of each of the supported organizations? Provide details in Part VI.

Did the organization exercise a substantial degree of direction over the policies, programs and activities of each of its supported organizations? If "Yes," describe in Part VI. the role played by the organization in this regard.

Schedule A (Form 990 or 990-EZ) 2015

Page 6

Part V

Type III Non-Functionally Integrated 509(a)(3) Supporting Organizations

Check here if the organization satisfied the Integral Part Test as a qualifying trust on Nov. 20, 1970. See instructions. All other Type III non-functionally integrated supporting organizations must complete Sections A through E.

	Section A - Adjusted Net Income		(A) Prior Year	(B) Current Year (optional)
1	Net short-term capital gain	1
2	Recoveries of prior-year distributions	2
3	Other gross income (see instructions)	3
4	Add lines 1 through 3	4
5	Depreciation and depletion	5
6	Portion of operating expenses paid or incurred for production or collection of gross income or for management, conservation, or maintenance of property held for production of income (see instructions)	6
7	Other expenses (see instructions)	7
8	Adjusted Net Income (subtract lines 5, 6 and 7 from line 4)	8

	Section B - Minimum Asset Amount		(A) Prior Year	(B) Current Year (optional)
1	Aggregate fair market value of all non-exempt-use assets (see instructions for short tax year or assets held for part of year):	1
a	Average monthly value of securities	1a
b	Average monthly cash balances	1b
c	Fair market value of other non-exempt-use assets	1c
d	Total (add lines 1a, 1b, and 1c)	1d
e	Discount claimed for blockage or other factors (explain in detail in Part VI):
2	Acquisition indebtedness applicable to non-exempt use assets	2
3	Subtract line 2 from line 1d	3
4	Cash deemed held for exempt use. Enter 1-1/2% of line 3 (for greater amount, see instructions).	4
5	Net value of non-exempt-use assets (subtract line 4 from line 3)	5
6	Multiply line 5 by .035	6
7	Recoveries of prior-year distributions	7
8	Minimum Asset Amount (add line 7 to line 6)	8

	Section C - Distributable Amount		Current Year
1	Adjusted net income for prior year (from Section A, line 8, Column A)	1
2	Enter 85% of line 1	2
3	Minimum asset amount for prior year (from Section B, line 8, Column A)	3
4	Enter greater of line 2 or line 3	4
5	Income tax imposed in prior year	5
6	Distributable Amount. Subtract line 5 from line 4, unless subject to emergency temporary reduction (see instructions)	6

Check here if the current year is the organization's first as a non-functionally-integrated Type III supporting organization (see instructions)

Schedule A (Form 990 or 990-EZ) 2015

Page 7

Part V

Type III Non-Functionally Integrated 509(a)(3) Supporting Organizations (continued)

Section D - Distributions		Current Year
1 Amounts paid to supported organizations to accomplish exempt purposes
2 Amounts paid to perform activity that directly furthers exempt purposes of supported organizations, in excess of income from activity
3 Administrative expenses paid to accomplish exempt purposes of supported organizations
4 Amounts paid to acquire exempt-use assets
5 Qualified set-aside amounts (prior IRS approval required)
6 Other distributions (describe in Part VI). See instructions
7Total annual distributions. Add lines 1 through 6.
8 Distributions to attentive supported organizations to which the organization is responsive (provide details in Part VI). See instructions
9 Distributable amount for 2015 from Section C, line 6
10 Line 8 amount divided by Line 9 amount

Section E - Distribution Allocations (see instructions)		(i) Excess Distributions	(ii) Underdistributions Pre-2015	(iii) Distributable Amount for 2015
1 Distributable amount for 2015 from Section C, line 6
2 Underdistributions, if any, for years prior to 2015 (reasonable cause required--see instructions)
3 Excess distributions carryover, if any, to 2015:
a
b
c
d From 2013.......
e From 2014.......
fTotal of lines 3a through e
g Applied to underdistributions of prior years
h Applied to 2015 distributable amount
i Carryover from 2010 not applied (see instructions)
j Remainder. Subtract lines 3g, 3h, and 3i from 3f.
4Distributions for 2015 from Section D, line 7:
$
a Applied to underdistributions of prior years
b Applied to 2015 distributable amount
c Remainder. Subtract lines 4a and 4b from 4.
5 Remaining underdistributions for years prior to 2015, if any. Subtract lines 3g and 4a from line 2 (if amount greater than zero, see instructions)
6 Remaining underdistributions for 2015. Subtract lines 3h and 4b from line 1 (if amount greater than zero, see instructions)
7 Excess distributions carryover to 2016. Add lines 3j and 4c.
8 Breakdown of line 7:
a
b
c Excess from 2013.......
d From 2014.......
e From 2015.......

Schedule A (Form 990 or 990-EZ) (2015)

Schedule A (Form 990 or 990-EZ) 2015

Page 8

Part VI

Supplemental Information. Provide the explanations required by Part II, line 10; Part II, line 17a or 17b; Part III, line 12; Part IV, Section A, lines 1, 2, 3b, 3c, 4b, 4c, 5a, 6, 9a, 9b, 9c, 11a, 11b, and 11c; Part IV, Section B, lines 1 and 2; Part IV, Section C, line 1; Part IV, Section D, lines 2 and 3; Part IV, Section E, lines 1c, 2a, 2b, 3a and 3b; Part V, line 1; Part V, Section B, line 1e; Part V Section D, lines 5, 6, and 8; and Part V, Section E, lines 2, 5, and 6. Also complete this part for any additional information. (See instructions).

Facts And Circumstances Test

Return Reference	Explanation
SCHEDULE A, PART II, COLUMN (B)	THE AMOUNTS INCLUDED IN PART II, COLUMN(B) ARE FOR A SHORT PERIOD, 12/01/2012 - 12/31/2012.

Schedule A (Form 990 or 990-EZ) 2015

Additional Data

Software ID:
Software Version:

- TIN:

Schedule B
(Form 990, 990-EZ,
or 990-PF)

Department of the Treasury
Internal Revenue Service

Schedule of Contributors

Attach to Form 990, 990-EZ, or 990-PF.

Information about Schedule B (Form 990, 990-EZ, or 990-PF) and its instructions is at www.irs.gov/form990.

OMB No. 1545-0047

2015

Name of the organization

THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE
FOUNDATION

Employer identification number

33-1092191

Organization type (check one):

Filers of:

Section:

Form 990 or 990-EZ

501(c)( ) (enter number) organization

4947(a)(1) nonexempt charitable trust not treated as a private foundation

527 political organization

Form 990-PF

501(c)(3) exempt private foundation

4947(a)(1) nonexempt charitable trust treated as a private foundation

501(c)(3) taxable private foundation

Check if your organization is covered by the General Rule or a Special Rule.
Note. Only a section 501(c)(7), (8), or (10) organization can check boxes for both the General Rule and a Special Rule. See instructions.

General Rule

For an organization filing Form 990, 990-EZ, or 990-PF that received, during the year, contributions totaling $5,000 or more (in money or other property) from any one contributor. Complete Parts I and II. See instructions for determining a contributor's total contributions.

Special Rules

For an organization described in section 501(c)(3) filing Form 990 or 990-EZ that met the 33¹/3% support test of the regulations
under sections 509(a)(1) and 170(b)(1)(A)(vi), that checked Schedule A (Form 990 or 990-EZ), Part II, line 13, 16a, or 16b, and that received from any one contributor, during the year, total contributions of the greater of (1) $5,000 or (2) 2% of the amount on (i) Form 990, Part VIII, line 1h, or (ii) Form 990-EZ, line 1. Complete Parts I and II.

For an organization described in section 501(c)(7), (8), or (10) filing Form 990 or 990-EZ that received from any one contributor,
during the year, total contributions of more than $1,000 exclusively for religious, charitable, scientific, literary, or educational purposes, or for the prevention of cruelty to children or animals. Complete Parts I, II, and III.

For an organization described in section 501(c)(7), (8), or (10) filing Form 990 or 990-EZ that received from any one contributor,
during the year, contributions exclusively for religious, charitable, etc., purposes, but no such contributions totaled more than $1,000. If this box is checked, enter here the total contributions that were received during the year for an exclusively religious, charitable, etc., purpose. Do not complete any of the parts unless the General Rule applies to this organization because it received nonexclusively religious, charitable, etc., contributions totaling $5,000 or more during the year ......... Arrow Bullet

Caution. An organization that is not covered by the General Rule and/or the Special Rules does not file Schedule B (Form 990,
990-EZ, or 990-PF), but it must answer “No” on Part IV, line 2, of its Form 990; or check the box on line H of its
Form 990-EZ or on its Form 990PF, Part I, line 2, to certify that it does not meet the filing requirements of Schedule B (Form 990,
990-EZ, or 990-PF).

For Paperwork Reduction Act Notice, see the Instructions
for Form 990, 990-EZ, or 990-PF.

Cat. No. 30613XSchedule B (Form 990, 990-EZ, or 990-PF) (2015)

Schedule B (Form 990, 990-EZ, or 990-PF) (2015) Page 2

Name of organization THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE FOUNDATION

Part I	Contributors (see instructions). Use duplicate copies of Part I if additional space is needed.
(a) No.	(b) Name, address, and ZIP + 4	(c) Total contributions	(d) Type of contribution
RESTRICTED	,	$ RESTRICTED	Person Payroll Noncash (Complete Part II for noncash contributions.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Total contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II for noncash contributions.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Total contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II for noncash contributions.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Total contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II for noncash contributions.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Total contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II for noncash contributions.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Total contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II for noncash contributions.)
Schedule B (Form 990, 990-EZ, or 990-PF) (2015)

Schedule B (Form 990, 990-EZ, or 990-PF) (2015)

Page 3

Name of organization THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE FOUNDATION		Employer identification number 33-1092191

Part II	Noncash Property (see instructions). Use duplicate copies of Part II if additional space is needed.
(a) No.from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (see instructions)	(d) Date received
		$
(a) No.from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (see instructions)	(d) Date received
		$
(a) No.from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (see instructions)	(d) Date received
		$
(a) No.from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (see instructions)	(d) Date received
		$
(a) No.from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (see instructions)	(d) Date received
		$
(a) No.from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (see instructions)	(d) Date received
		$
Schedule B (Form 990, 990-EZ, or 990-PF) (2015)

Schedule B (Form 990, 990-EZ, or 990-PF) (2015)

Page 4


Name of organization THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE FOUNDATION			Employer identification number 33-1092191
Part III Exclusively religious, charitable, etc., contributions to organizations described in section 501(c)(7), (8), or (10) that total more than $1,000 for the year from any one contributor. Complete columns (a) through (e) and the following line entry. For organizations completing Part III, enter the total of exclusively religious, charitable, etc., contributions of $1,000 or less for the year. (Enter this information once. See instructions.) $ Use duplicate copies of Part III if additional space is needed.

(a)
No.from Part I

(b) Purpose of gift

(d) Description of how gift is held

(e) Transfer of gift
Transferee's name, address, and ZIP 4	Relationship of transferor to transferee

(a)
No.from Part I

(b) Purpose of gift

(d) Description of how gift is held

(e) Transfer of gift
Transferee's name, address, and ZIP 4	Relationship of transferor to transferee

(a)
No.from Part I

(b) Purpose of gift

(d) Description of how gift is held

(e) Transfer of gift
Transferee's name, address, and ZIP 4	Relationship of transferor to transferee

(a)
No.from Part I

(b) Purpose of gift

(d) Description of how gift is held

(e) Transfer of gift
Transferee's name, address, and ZIP 4	Relationship of transferor to transferee

Schedule B (Form 990, 990-EZ, or 990-PF) (2015)

Additional Data

Software ID:
Software Version:

- TIN:

SCHEDULE D
(Form 990)

Department of the Treasury
Internal Revenue Service

Supplemental Financial Statements

Complete if the organization answered "Yes," on Form 990,
Part IV, line 6, 7, 8, 9, 10, 11a, 11b, 11c, 11d, 11e, 11f, 12a, or 12b.
SchDMd Bullet

Attach to Form 990.
Information about Schedule D (Form 990) and its instructions is at www.irs.gov/form990.

OMB No. 1545-0047

2015

Open to Public Inspection

Name of the organization

THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE
FOUNDATION

Employer identification number

33-1092191

Part I

Organizations Maintaining Donor Advised Funds or Other Similar Funds or Accounts. Complete if the organization answered "Yes" on Form 990, Part IV, line 6.

			(a) Donor advised funds	(b) Funds and other accounts

1	Total number at end of year ....
2	Aggregate value of contributions to (during year)
3	Aggregate value of grants from (during year)
4	Aggregate value at end of year ....

Did the organization inform all donors and donor advisors in writing that the assets held in donor advised
funds are the organization's property, subject to the organization's exclusive legal control? ...........

Yes No

Did the organization inform all grantees, donors, and donor advisors in writing that grant funds can be
used only for charitable purposes and not for the benefit of the donor or donor advisor, or for any other purpose conferring impermissible private benefit? ............................

Yes No

Part II

Conservation Easements. Complete if the organization answered "Yes" on Form 990, Part IV, line 7.

Purpose(s) of conservation easements held by the organization (check all that apply).

Preservation of land for public use (e.g., recreation or education) Preservation of an historically important land area

Protection of natural habitat Preservation of a certified historic structure

Preservation of open space

Complete lines 2a through 2d if the organization held a qualified conservation contribution in the form of a conservation easement on the last day of the tax year.


a	Total number of conservation easements ......................	2a
b	Total acreage restricted by conservation easements ....................	2b
c	Number of conservation easements on a certified historic structure included in (a) .....	2c
d	Number of conservation easements included in (c) acquired after 8/17/06, and not on a historic structure listed in the National Register ...	2d

Number of conservation easements modified, transferred, released, extinguished, or terminated by the organization during the
tax year SchDMd Bullet

Number of states where property subject to conservation easement is located SchDMd Bullet

Does the organization have a written policy regarding the periodic monitoring, inspection, handling of violations, and enforcement of the conservation easements it holds? ............

Yes No

Staff and volunteer hours devoted to monitoring, inspecting, handling of violations, and enforcing conservation easements during the year
SchDMd Bullet

Amount of expenses incurred in monitoring, inspecting, handling of violations, and enforcing conservation easements during the year
SchDMd Bullet

Does each conservation easement reported on line 2(d) above satisfy the requirements of section 170(h)(4)(B)(i) and section 170(h)(4)(B)(ii)? .............................

Yes No

In Part XIII, describe how the organization reports conservation easements in its revenue and expense statement, and
balance sheet, and include, if applicable, the text of the footnote to the organization’s financial statements that describes
the organization’s accounting for conservation easements.

Part III

Organizations Maintaining Collections of Art, Historical Treasures, or Other Similar Assets.
Complete if the organization answered "Yes" on Form 990, Part IV, line 8.

If the organization elected, as permitted under SFAS 116 (ASC 958), not to report in its revenue statement and balance sheet works of art, historical treasures, or other similar assets held for public exhibition, education, or research in furtherance of public service, provide, in Part XIII, the text of the footnote to its financial statements that describes these items.

If the organization elected, as permitted under SFAS 116 (ASC 958), to report in its revenue statement and balance sheet works of art, historical treasures, or other similar assets held for public exhibition, education, or research in furtherance of public service, provide the following amounts relating to these items:

(i)

Revenue included on Form 990, Part VIII, line 1 ......................... SchDMd Bullet

(ii)

Assets included in Form 990, Part X ............................... SchDMd Bullet

If the organization received or held works of art, historical treasures, or other similar assets for financial gain, provide the
following amounts required to be reported under SFAS 116 (ASC 958) relating to these items:

Revenue included on Form 990, Part VIII, line 1 .......................... SchDMd Bullet

Assets included in Form 990, Part X ............................... SchDMd Bullet

For Paperwork Reduction Act Notice, see the Instructions for Form 990.

Cat. No. 52283D

Schedule D (Form 990) 2015

Page 2

Part III

Organizations Maintaining Collections of Art, Historical Treasures, or Other Similar Assets (continued)

Using the organization’s acquisition, accession, and other records, check any of the following that are a significant use of its collection items (check all that apply):

Public exhibition

Loan or exchange programs

Scholarly research

Other

Preservation for future generations

Provide a description of the organization’s collections and explain how they further the organization’s exempt purpose in
Part XIII.

During the year, did the organization solicit or receive donations of art, historical treasures or other similar
assets to be sold to raise funds rather than to be maintained as part of the organization’s collection?...

Yes No

Part IV

Escrow and Custodial Arrangements. Complete if the organization answered "Yes" on Form 990, Part IV, line 9, or reported an amount on Form 990, Part X, line 21.

Is the organization an agent, trustee, custodian or other intermediary for contributions or other assets not
included on Form 990, Part X? ....................................

Yes No


b	If "Yes," explain the arrangement in Part XIII and complete the following table:		Amount
c	Beginning balance .............................	1c
d	Additions during the year ............................	1d
e	Distributions during the year ..........................	1e
f	Ending balance ................................	1f

Did the organization include an amount on Form 990, Part X, line 21, for escrow or custodial account liability?

Yes No

If "Yes," explain the arrangement in Part XIII. Check here if the explanation has been provided in Part XIII ........

Part V

Endowment Funds. Complete if the organization answered "Yes" on Form 990, Part IV, line 10.

		(a)Current year	(b)Prior year	(c)Two years back	(d)Three years back	(e)Four years back

1a	Beginning of year balance ....	62,093	62,093	62,093	62,093	62,093
b	Contributions ...
c	Net investment earnings, gains, and losses	7,353	6,500	7,353	566	6,787
d	Grants or scholarships ...
e	Other expenditures for facilities and programs ...	7,353	6,500	7,353	566	6,787
f	Administrative expenses ....
g	End of year balance ......	62,093	62,093	62,093	62,093	62,093

Provide the estimated percentage of the current year end balance (line 1g, column (a)) held as:

Board designated or quasi-endowment SchDMd Bullet

Permanent endowment SchDMd Bullet

100.000 %

Temporarily restricted endowment SchDMd Bullet

The percentages on lines 2a, 2b, and 2c should equal 100%.

Are there endowment funds not in the possession of the organization that are held and administered for the
organization by:

Yes

(i) unrelated organizations .................

3a(i)

(ii) related organizations .................

3a(ii)

Yes

If "Yes" on 3a(ii), are the related organizations listed as required on Schedule R? .........

Yes

Describe in Part XIII the intended uses of the organization's endowment funds.

Part VI

Land, Buildings, and Equipment.
Complete if the organization answered 'Yes' on Form 990, Part IV, line 11a. See Form 990, Part X, line 10.

Description of property		(a) Cost or other basis (investment)	(b)Cost or other basis (other)	(c) Accumulated depreciation	(d) Book value

1a	Land ...
b	Buildings
c	Leasehold improvements
d	Equipment ...
e	Other ...
Total. Add lines 1a through 1e. (Column (d) must equal Form 990, Part X, column (B), line 10(c).)..

Schedule D (Form 990) 2015

Page 3

Part VII

InvestmentsOther Securities. Complete if the organization answered 'Yes' on Form 990, Part IV, line 11b. See Form 990, Part X, line 12.

(a) Description of security or category (including name of security)	(b)Book value	(c)Method of valuation: Cost or end-of-year market value
(1)Financial derivatives
(2)Closely-held equity interests
(3)Other
(A)
(B)
(C)
(D)
(E)
(F)
(G)
(H)
Total. (Column (b) must equal Form 990, Part X, col. (B) line 12.)

Part VIII

InvestmentsProgram Related. Complete if the organization answered 'Yes' on Form 990, Part IV, line 11c. See Form 990, Part X, line 13.

(a) Description of investment	(b) Book value	(c) Method of valuation: Cost or end-of-year market value

(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
Total. (Column (b) must equal Form 990, Part X, col.(B) line 13.)

Part IX

Other Assets. Complete if the organization answered 'Yes' on Form 990, Part IV, line 11d. See Form 990, Part X, line 15.

(a) Description				(b) Book value

(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
Total. (Column (b) must equal Form 990, Part X, col.(B) line 15.)...........

Part X

Other Liabilities. Complete if the organization answered 'Yes' on Form 990, Part IV, line 11e or 11f. See Form 990, Part X, line 25.

1.(a) Description of liability	(b) Book value
(1) Federal income taxes	0

(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
Total. (Column (b) must equal Form 990, Part X, col.(B) line 25.)	0
2. Liability for uncertain tax positions. In Part XIII, provide the text of the footnote to the organization's financial statements that reports the organization's liability for uncertain tax positions under FIN 48 (ASC 740). Check here if the text of the footnote has been provided in Part XIII

Schedule D (Form 990) 2015

Page 4

Part XI Reconciliation of Revenue per Audited Financial Statements With Revenue per Return Complete if the organization answered 'Yes' on Form 990, Part IV, line 12a.
1	Total revenue, gains, and other support per audited financial statements .......		1
2	Amounts included on line 1 but not on Form 990, Part VIII, line 12:
a	Net unrealized gains (losses) on investments ....	2a
b	Donated services and use of facilities .........	2b
c	Recoveries of prior year grants ...........	2c
d	Other (Describe in Part XIII.) ............	2d
e	Add lines 2a through 2d .....................		2e
3	Subtract line 2e from line 1..................		3
4	Amounts included on Form 990, Part VIII, line 12, but not on line 1:
a	Investment expenses not included on Form 990, Part VIII, line 7b .	4a
b	Other (Describe in Part XIII.) ...........	4b
c	Add lines 4a and 4b....................		4c
5	Total revenue. Add lines 3 and 4c. (This must equal Form 990, Part I, line 12.) ......		5

Part XII Reconciliation of Expenses per Audited Financial Statements With Expenses per Return. Complete if the organization answered 'Yes' on Form 990, Part IV, line 12a.
1	Total expenses and losses per audited financial statements ...........		1
2	Amounts included on line 1 but not on Form 990, Part IX, line 25:
a	Donated services and use of facilities .........	2a
b	Prior year adjustments ............	2b
c	Other losses ................	2c
d	Other (Describe in Part XIII.) ............	2d
e	Add lines 2a through 2d....................		2e
3	Subtract line 2e from line 1...................		3
4	Amounts included on Form 990, Part IX, line 25, but not on line 1:
a	Investment expenses not included on Form 990, Part VIII, line 7b ..	4a
b	Other (Describe in Part XIII.) ............	4b
c	Add lines 4a and 4b.....................		4c
5	Total expenses. Add lines 3 and 4c. (This must equal Form 990, Part I, line 18.) ......		5

Part XIII

Supplemental Information

Provide the descriptions required for Part II, lines 3, 5, and 9; Part III, lines 1a and 4; Part lV, lines 1b and 2b;
Part V, line 4; Part X, line 2; Part XI, lines 2d and 4b; and Part XII, lines 2d and 4b. Also complete this part to provide any additional information.

Return Reference

Explanation

SCHEDULE D, PART V, LINE 4

TGEN FOUNDATION CLASSIFIES AS PERMANENTLY RESTRICTED NET ASSETS (1) THE ORIGINAL VALUE OF THE GIFT DONATED TO THE PERMANENT ENDOWMENT, (2) THE ORIGINAL VALUE OF SUBSEQUENT GIFTS DONATED TO THE PERMANENT ENDOWMENT, AND (3) ACCUMULATIONS TO THE PERMANENT ENDOWMENT MADE IN ACCORDANCE WITH THE DIRECTION OF THE APPLICABLE DONOR GIFT INSTRUMENT. TGEN FOUNDATION HAS A RESTRICTED ASSET WHICH ALLOWS THEM TO USE ANY INVESTMENT INCOME FOR OPERATING EXPENSES.

SCHEDULE D, PART X, LINE 2

MANAGEMENT IS OF THE OPINION THAT SUBSTANTIALLY ALL OF TGEN'S AND THE FOUNDATION'S ACTIVITIES ARE RELATED TO THEIR EXEMPT PURPOSES, AND NO MATERIAL UNCERTAIN TAX POSITIONS HAVE BEEN IDENTIFIED OR RECORDED IN THE ACCOMPANYING CONSOLIDATED FINANCIAL STATEMENTS AT DECEMBER 31, 2015 OR 2014. TGEN AND THE FOUNDATION FILE FORMS 990 IN THE U.S. FEDERAL JURISDICTION AND COMPARABLE FORMS IN THE STATE OF ARIZONA. TAX FILINGS FOR 2012 THROUGH 2015 ARE SUBJECT TO EXAMINATION; HOWEVER, THE INSTITUTE HAS NOT BEEN NOTIFIED OF ANY SUCH EXAMINATIONS.

Schedule D (Form 990) 2015

Additional Data

Software ID:
Software Version:

- TIN:

Schedule I
(Form 990)

Department of the Treasury
Internal Revenue Service

Grants and Other Assistance to Organizations,
Governments and Individuals in the United States

Complete if the organization answered "Yes," on Form 990, Part IV, line 21 or 22.
lBullet

Attach to Form 990.
lBullet

Information about Schedule I (Form 990) and its instructions is at www.irs.gov/form990.

OMB No. 1545-0047

2015

Open to Public
Inspection

Name of the organization
THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE
FOUNDATION

Employer identification number
33-1092191

Part I

General Information on Grants and Assistance

Does the organization maintain records to substantiate the amount of the grants or assistance, the grantees' eligibility for the grants or assistance, and
the selection criteria used to award the grants or assistance? ........................

Yes No

Describe in Part IV the organization's procedures for monitoring the use of grant funds in the United States.

Part II

Grants and Other Assistance to Domestic Organizations and Domestic Governments. Complete if the organization answered "Yes" on Form 990, Part IV, line 21, for any recipient

that received more than $5,000. Part II can be duplicated if additional space is needed.

(a) Name and address of organization or government	(b) EIN	(c) IRC section if applicable	(d) Amount of cash grant	(e) Amount of non-cash assistance	(f) Method of valuation (book, FMV, appraisal, other)	(g) Description of non-cash assistance	(h) Purpose of grant or assistance

(1) TRANSLATIONAL GENOMICS RESEARCH INSTITUTE
445 N 5TH ST SUITE 600
PHOENIX,AZ85004

75-3065445

501(c)(3)

6,881,065

FUNDRAISING FOR TGEN

Enter total number of section 501(c)(3) and government organizations listed in the line 1 table ................. Bullet Image

Enter total number of other organizations listed in the line 1 table ........................ . Bullet Image

For Paperwork Reduction Act Notice, see the Instructions for Form 990.

Cat. No. 50055P

Schedule I (Form 990) 2015

Page 2

Part III

Grants and Other Assistance to Domestic Individuals. Complete if the organization answered "Yes" on Form 990, Part IV, line 22.
Part III can be duplicated if additional space is needed.

(a) Type of grant or assistance	(b) Number of recipients	(c) Amount of cash grant	(d) Amount of non-cash assistance	(e) Method of valuation (book, FMV, appraisal, other)	(f) Description of non-cash assistance

(1)
(2)
(3)
(4)
(5)
(6)
(7)

Part IV

Supplemental Information. Provide the information required in Part I, line 2, Part III, column (b), and any other additional information.

Return Reference	Explanation
SCHEDULE I, PART I, LINE 2	THE FOUNDATION IS ORGANIZED EXCLUSIVELY TO BENEFIT TGEN, A RELATED 501(C)(3) TAX-EXEMPT ORGANIZATION, BY SUPPORTING TGEN'S FUNDRAISING AND DEVELOPMENT FUNCTIONS. THE FOUNDATION RELIES UPON THE GOVERNANCE PRACTICES OF TGEN TO MONITOR USE OF GRANT FUNDS.

Schedule I (Form 990) 2015

Additional Data

Software ID:
Software Version:

- TIN:

Schedule J
(Form 990)

Department of the Treasury
Internal Revenue Service

Compensation Information

For certain Officers, Directors, Trustees, Key Employees, and Highest
Compensated Employees
SchJMediumBullet

Complete if the organization answered "Yes" on Form 990, Part IV, line 23.
SchJMediumBullet

Attach to Form 990.
SchJMediumBullet

Information about Schedule J (Form 990) and its instructions is at www.irs.gov/form990.

OMB No. 1545-0047

2015

Open to Public Inspection

Name of the organization

THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE
FOUNDATION

Employer identification number

33-1092191

Part I

Questions Regarding Compensation

Yes

Check the appropiate box(es) if the organization provided any of the following to or for a person listed on Form
990, Part VII, Section A, line 1a. Complete Part III to provide any relevant information regarding these items.

First-class or charter travel Housing allowance or residence for personal use

Travel for companions Payments for business use of personal residence

Tax idemnification and gross-up payments Health or social club dues or initiation fees

Discretionary spending account Personal services (e.g., maid, chauffeur, chef)

If any of the boxes in line 1a are checked, did the organization follow a written policy regarding payment or reimbursement or provision of all of the expenses described above? If "No," complete Part III to explain .........

Did the organization require substantiation prior to reimbursing or allowing expenses incurred by all
directors, trustees, officers, including the CEO/Executive Director, regarding the items checked in line 1a? ..

Indicate which, if any, of the following the filing organization used to establish the compensation of the
organization's CEO/Executive Director. Check all that apply. Do not check any boxes for methods
used by a related organization to establish compensation of the CEO/Executive Director, but explain in Part III.

Compensation committee Written employment contract

Independent compensation consultant Compensation survey or study

Form 990 of other organizations Approval by the board or compensation committee

During the year, did any person listed on Form 990, Part VII, Section A, line 1a with respect to the filing organization or a related organization:

Receive a severance payment or change-of-control payment? ................

Participate in, or receive payment from, a supplemental nonqualified retirement plan? .........

Participate in, or receive payment from, an equity-based compensation arrangement? .........

If "Yes" to any of lines 4a-c, list the persons and provide the applicable amounts for each item in Part III.

Only 501(c)(3), 501(c)(4), and 501(c)(29) organizations must complete lines 5-9.

For persons listed on Form 990, Part VII, Section A, line 1a, did the organization pay or accrue any
compensation contingent on the revenues of:

The organization? ...........................

Any related organization?

If "Yes," on line 5a or 5b, describe in Part III.

For persons listed on Form 990, Part VII, Section A, line 1a, did the organization pay or accrue any
compensation contingent on the net earnings of:

The organization?

Any related organization? .........................

If "Yes," on line 6a or 6b, describe in Part III.

For persons listed on Form 990, Part VII, Section A, line 1a, did the organization provide any non-fixed
payments not described in lines 5 and 6? If "Yes," describe in Part III ............

Yes

Were any amounts reported on Form 990, Part VII, paid or accured pursuant to a contract that was
subject to the initial contract exception described in Regulations section 53.4958-4(a)(3)? If "Yes," describe
in Part III .............................

If "Yes" on line 8, did the organization also follow the rebuttable presumption procedure described in Regulations section 53.4958-6(c)? .........................

For Paperwork Reduction Act Notice, see the Instructions for Form 990.

Cat. No. 50053T

Schedule J (Form 990) 2015

Page 2

Part II

Officers, Directors, Trustees, Key Employees, and Highest Compensated Employees. Use duplicate copies if additional space is needed.

For each individual whose compensation must be reported on Schedule J, report compensation from the organization on row (i) and from related organizations, described in the
instructions, on row (ii). Do not list any individuals that are not listed on Form 990, Part VII.
Note. The sum of columns (B)(i)-(iii) for each listed individual must equal the total amount of Form 990, Part VII, Section A, line 1a, applicable column (D) and (E) amounts for that individual.

(A) Name and Title		(B) Breakdown of W-2 and/or 1099-MISC compensation			(C) Retirement and other deferred compensation	(D) Nontaxable benefits	(E) Total of columns (B)(i)-(D)	(F) Compensation in column(B) reported as deferred on prior Form 990
(A) Name and Title		(i) Base compensation	(ii) Bonus & incentive compensation	(iii) Other reportable compensation	(C) Retirement and other deferred compensation	(D) Nontaxable benefits	(E) Total of columns (B)(i)-(D)
1Michael BassoffPresident, TGen Foundation	(i) (ii)	0 ------------- 465,336	0 ------------- 0	0 ------------- 18,696	0 ------------- 10,600	0 ------------- 10,477	0 ------------- 505,109	0 ------------- 0
2Teresa BurlesonBOARD MBR/ASST SEC/ASST treaS	(i) (ii)	0 ------------- 430,331	0 ------------- 116,667	0 ------------- 982	0 ------------- 48,100	0 ------------- 7,284	0 ------------- 603,364	0 ------------- 100,000
3Jeffrey M Trent PhDBoard Member	(i) (ii)	0 ------------- 965,834	0 ------------- 0	0 ------------- 34,133	0 ------------- 210,600	0 ------------- 10,196	0 ------------- 1,220,763	0 ------------- 0
4CHARLES K COLESONCHIEF FINANCIAL OFFICER	(i) (ii)	0 ------------- 141,107	0 ------------- 15,000	0 ------------- 1,715	0 ------------- 1,924	0 ------------- 50	0 ------------- 159,796	0 ------------- 0

Schedule J (Form 990) 2015

Page 3

Part III

Supplemental Information

Provide the information, explanation, or descriptions required for Part I, lines 1a, 1b, 3, 4a, 4b, 4c, 5a, 5b, 6a, 6b, 7, and 8, and for Part II. Also complete this part for any additional information.

Return Reference	Explanation
SCHEDULE J, PART I, LINE 1A	FIRST CLASS TRAVEL IS PERMITTED BY EXECUTIVE STAFF ONLY AND MUST, PER TGEN POLICY, BE PRE-APPROVED BY THE CHIEF OPERATING OFFICER. THESE EXPENSES WERE NOT CONSIDERED AS TAXABLE COMPENSATION TO THE RECIPIENT SINCE THEY WERE REIMBURSEMENTS FOR BUSINESS USE UNDER AN ACCOUNTABLE PLAN. TGEN, A RELATED TAX-EXEMPT ORGANIZATION, PROVIDES THIS BENEFIT.
SCHEDULE J, PART I, LINE 3	TGEN FOUNDATION DOES NOT DETERMINE OR PAY ANY COMPENSATION OR BENEFITS. ALL COMPENSATION AND BENEFITS ARE DETERMINED AND PAID BY TGEN, A RELATED TAX-EXEMPT ORGANIZATION.
SCHEDULE J, PART I, LINE 7	SOME OF THE PERSONS LISTED IN FORM 990, PART VII, WERE PAID BONUSES WHICH WERE BASED ON ACCOMPLISHMENTS OF SPECIFIC MILESTONES AND/OR PERFORMANCE BASES, AS APPROVED BY THE TGEN BOARD OF DIRECTORS.
SCHEDULE J, PART II	DEFERRED COMPENSATION INCLUDES RETENTION AGREEMENTS FOR DR. JEFFREY TRENT AND TERESA BURLESON. DR. TRENT IS ELIGIBLE TO RECEIVE $400,000 ON 03/12/2017 AND TERESA BURLESON IS ELIGIBLE TO RECEIVE $250,000 ON 03/31/2020 PAYABLE BY TGEN. AMOUNTS ACCRUED BY TGEN DURING CALENDAR YEAR 2015 UNDER THESE AGREEMENTS HAVE BEEN REPORTED IN SCHEDULE J, PART II, COLUMN (C) AS DEFERRED COMPENSATION AS FOLLOWS: JEFFERY M. TRENT, PH.D. $200,000 TERESA BURLESON $37,500 TERESA BURLESON RECEIVED $116,667 FROM A RETENTION AGREEMENT IN WHICH SHE VESTED 3/31/2015.

Schedule J (Form 990) 2015

Additional Data

Software ID:
Software Version:

- TIN:

SCHEDULE O
(Form 990 or 990-EZ)

Department of the Treasury
Internal Revenue Service

Supplemental Information to Form 990 or 990-EZ

Complete to provide information for responses to specific questions on
Form 990 or 990-EZ or to provide any additional information.
MediumBullet

Attach to Form 990 or 990-EZ.
MediumBullet

Information about Schedule O (Form 990 or 990-EZ) and its instructions is at
www.irs.gov/form990.

OMB No. 1545-0047

2015

Open to Public
Inspection

Name of the organization

THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE
FOUNDATION

Employer identification number

33-1092191

Return Reference	Explanation
FORM 990, PART III, LINE 4A	THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE FOUNDATION RAISES FUNDS FOR THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE ("TGEN"). THE PROGRAM SERVICE ACCOMPLISHMENTS OF TGEN ARE LISTED BELOW:
INTRODUCTION	TGEN CONTINUES TO BE AT THE FOREFRONT OF SCIENTIFIC INNOVATION AND DISCOVERY, USING OUR TECHNOLOGICAL EXPERTISE TO PROVIDE PATIENTS AND THEIR PHYSICIANS WITH THE BEST POSSIBLE INFORMATION TO HELP DIAGNOSE AND TREAT DISEASE. IN 2015, EARLY DETECTION OF DISEASE WAS A MAIN FOCUS OF TGEN INITIATIVES. WE MADE SIGNIFICANT PROGRESS IN THIS AREA OF RESEARCH BY NEARLY ALL MEASURES. ESPECIALLY NOTABLE IS A STUDY THAT ALIGNS OUR MASTERY OF GENE SEQUENCING WITH EFFORTS TO CREATE METHODS OF EARLY DETECTION OF CANCER, AND IN THIS CASE POTENTIALLY THROUGH THE USE OF A SIMPLE BLOOD TEST, OR LIQUID BIOPSY. THE RESULTS OF THIS STUDY, PUBLISHED IN CLINICAL EPIGENETICS, DETAILED THE IDENTIFICATION OF 21 DNA HYPER METHYLATION HOTSPOTS - GENE LOCATIONS ALONG THE 3 BILLION CHEMICAL BASES OF DNA - WITH INCREASED LEVELS OF METHYLATION THAT COULD INDICATE THE EXISTENCE OF METASTATIC BREAST CANCER. THESE FINDINGS COULD LEAD TO A HIGHLY SENSITIVE BLOOD-BASED TEST PANEL (A TYPE OF LIQUID BIOPSY), WHICH COULD HELP IMPROVE THE CARE OF WOMEN WITH BREAST CANCER. THE TEST WOULD LOOK FOR BIOMARKERS DERIVED FROM CELL-FREE STRANDS OF DNA (CFDNA) CIRCULATING IN THE BLOOD. THIS BREAKTHROUGH HAS SIGNIFICANT IMPLICATIONS FOR ALL BREAST CANCER PATIENTS IN THE FUTURE, SINCE ALL SUBTYPES OF BREAST CANCER IN VARYING DEGREES CAN REOCCUR AND METASTASIZE. THIS TEST COULD PROVIDE PHYSICIANS WITH CRITICAL INFORMATION ABOUT THERAPIES, ESPECIALLY FOLLOWING SURGERY OR SESSIONS OF CHEMOTHERAPY. ANOTHER TGEN-LED PROJECT, FUNDED BY THE SEENA MAGOWITZ FOUNDATION AND STAND UP TO CANCER (SU2C), IS ADVANCING TREATMENT OF LATE-STAGE PANCREATIC CANCER PATIENTS THROUGH OUR CLINICAL PARTNERSHIP AT HONORHEALTH (FORMERLY SCOTTSDALE HEALTHCARE). ONE PATIENT WHO ARRIVED AT THE CLINIC LAST APRIL WITH STAGE 4 PANCREATIC CANCER NOW HAS NO DETECTABLE TUMORS, THANKS TO A CLINICAL TRIAL THAT BUILT ON OUR SUCCESS IN TESTING - AND GAINING FDA APPROVAL - OF THE GEMCITABINE/ABRAXANE COMBINATION AS THE NEW STANDARD OF CARE FOR THESE PATIENTS. THE AMERICAN SOCIETY OF CLINICAL ONCOLOGY (ASC0) RECOGNIZED THE GROUNDBREAKING WORK AT TGEN BY INCLUDING AN OVARIAN CANCER STUDY LED BY TGEN PRESIDENT DR. JEFFREY TRENT IN ITS ANNUAL CLINICAL CANCER ADVANCES REPORT, PUBLISHED JAN. 20, IDENTIFYING THE STUDY AS ONE OF THE YEARS TOP RESEARCH PAPERS, WHICH WAS PUBLISHED IN NATURE GENETICS. TGEN WAS ABLE TO IDENTIFY THE LIVELY GENETIC DRIVER OF THIS PARTICULARLY AGGRESSIVE TYPE OF OVARIAN CANCER THAT MOSTLY STRIKES YOUNG WOMEN AND GIRLS. FACULTY WITHIN OUR PATHOGEN GENOMICS DIVISION, TGEN NORTH, PARTICIPATED IN THE DESIGN OF NEW GENOMICS-BASED METHODS FOR ACCURATELY DIAGNOSING VALLEY FEVER AND LYME DISEASE. CREATING A DEFINITIVE, LOW-COST AND ACCURATE DIAGNOSTIC TOOL FOR BOTH DISEASES GREATLY BENEFITS PATIENT HEALTH SINCE SYMPTOMS IN BOTH DISEASES ARE SIMILAR TO OTHER AILMENTS, AND THE CURRENT TESTS ARE SO UNRELIABLE THEY HAVE BEEN COMPARED TO COIN FLIPS. AS A RESULT, BOTH VALLEY FEVER AND LYME DISEASE ARE OFTEN MISDIAGNOSED AND MISTREATED. TGEN NORTHS NEW TESTS WILL CHANGE THAT. A COLLABORATION WITH BAYLOR RESEARCH INSTITUTE (BRI), DALLAS, FOCUSES ON ACCELERATING EARLY DETECTION AND TREATMENTS FOR PATIENTS WITH A BROAD RANGE OF CANCERS. THIS AGREEMENT ALIGNS THE BEST SCIENCE FROM BOTH INSTITUTIONS, LEADING TO NEW CLINICAL TRIALS AND ACCESS TO TECHNOLOGY TO DRIVE THE DEVELOPMENT OF NEW THERAPIES, STARTING AT BAYLOR SCOTT & WHITE HEALTH'S 49 HOSPITALS THROUGHOUT TEXAS. AS A MEASURE OF OUR IMPACT IN THE COMMUNITY, TGEN DISTINGUISHED PROFESSOR AND PHYSICIAN-IN-CHIEF, DR. DANIEL VON HOFF, RECEIVED THE 2015 WALLACE A. REED M.D. AWARD BY THE ARIZONA MEDICAL ASSOCIATION, RECOGNIZING HIS MANY INNOVATIVE CONTRIBUTIONS TO THE ADVANCEMENT OF CANCER CARE, ESPECIALLY IN THE REALM OF PANCREATIC CANCER, ONE OF THE MOST DIFFICULT TO TREAT OF ALL CANCER TYPES. BUILDING ON OUR EXPERTISE WITH HELIOS EDUCATION FOUNDATION IN TRAINING THE NEXT GENERATION OF PHYSICIANS AND RESEARCH SCIENTISTS, WE CONDUCTED A PILOT PROGRAM WITH THE SCOTTSDALE UNIFIED SCHOOL DISTRICT THAT PROVIDES TEACHERS WITH STRONG FLUENCY IN BIOMEDICAL RESEARCH. THE EXCELLENCE IN BIOSCIENCE TEACHER INITIATIVE CONSISTED OF AN INTENSIVE, THREE-DAY SERIES OF PRESENTATIONS, INTERACTIVE DISCUSSIONS AND PRACTICAL EXPERIENCES LED BY TGEN BIO-MEDICAL EXPERTS. IN OCTOBER, THE FOOD AND DRUG ADMINISTRATION (FDA) APPROVED A DRUG, ONIVYDE, FOR ADVANCED PANCREATIC CANCER, BASED ON TGEN-LED RESEARCH AND CLINICAL TRIALS, PROVIDING PATIENTS NEW TREATMENT OPTIONS. BRAIN CANCER RESEARCH, FUNDED BY THE BEN & CATHERINE IVY FOUNDATION, PRODUCED SEVERAL NOTABLE ADVANCEMENTS. ONE TGEN STUDY SHOWED THAT A DRUG, PROPENTOFYLLINE, PREVIOUSLY DEVELOPED FOR DEMENTIA, KNOCKS DOWN A PROTEIN THAT PROMOTES THE SPREAD OF THE BRAIN CANCER GLIOBLASTOMA, INCREASES SENSITIVITY TO A STANDARD CHEMOTHERAPY DRUG, AND INHIBITS GLIOBLASTOMA CELL INVASION. THIS NOW BECOMES A TARGET OF TREATMENT-FOCUSED RESEARCH. NEUROGENOMICS FACULTY ALSO COMPLETED A THIRD SEASON OF A CONCUSSION/BRAIN INJURY STUDY WITH RIDDELL, THE ARIZONA STATE UNIVERSITYS FOOTBALL TEAM - ALONG WITH BARROW NEUROLOGICAL INSTITUTE, AND A.T. STILL UNIVERSITY - TO DISCOVER BIOMARKERS THAT MIGHT INDICATE WHEN AN ATHLETE IS TOO HURT TO PLAY. ADDITIONALLY, THE FOLLOWING SUMMARY PROVIDES A SNAPSHOT OF PROGRESS IN CLINICAL RESEARCH AND CLINICAL TRIALS, SCIENTIFIC PUBLICATIONS, GRANTS, CONTRACTS, PHILANTHROPY, EDUCATION AND OUTREACH, MEDIA AND COMMUNITY RECOGNITION.
CLINICAL RESEARCH AND CLINICAL TRIALS	IN 2015, TGEN ADVANCED A SERIES OF INNOVATIVE RESEARCH INITIATIVES THAT YIELDED NUMEROUS SCIENTIFIC DISCOVERIES (ALL WITH THE POTENTIAL FOR CLINICAL APPLICATION), ESTABLISHED NATIONAL AND INTERNATIONAL COLLABORATIONS, AND LED NEW AND EXCITING CLINICAL TRIALS WITH PROMISING RESULTS. NOTABLE ARE: - IN EARLY MAY, WE ANNOUNCED A COLLABORATION WITH DALLAS, TEXAS-BASED BAYLOR HEALTHCARE AND RESEARCH INSTITUTE FOCUSED ON ACCELERATING EARLY DETECTION AND TREATMENTS FOR PATIENTS WITH A BROAD RANGE OF CANCERS. THIS AGREEMENT FORGES THE BEST SCIENCE OF BOTH INSTITUTIONS, LEADING TO NEW CLINICAL TRIALS AND ACCESS TO TECHNOLOGY TO DRIVE THE DEVELOPMENT OF NEW THERAPIES, STARTING AT BAYLOR SCOTT & WHITE HEALTH'S 49 HOSPITALS THROUGHOUT TEXAS. - THE WEEK PRIOR TO THE TGEN-BAYLOR ANNOUNCEMENT, PREVIOUS COLLABORATIVE WORK BETWEEN OUR INSTITUTIONS LED THE AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR) TO ANNOUNCE THAT A SCIENTIFIC PAPER DESCRIBING POTENTIAL DRUG TARGETS FOLLOWING THE UNPRECEDENTED GENOMIC SEQUENCING OF 14 METASTATIC TRIPLE-NEGATIVE BREAST CANCER PATIENTS WAS THE MOST CITED STUDY IN 2013 OF ANY PUBLISHED THAT YEAR BY AACR'S JOURNAL MOLECULAR CANCER THERAPEUTICS. - IN EARLY NOVEMBER, STAND UP TO CANCER (SU2C) SELECTED DR. VON HOFF AND HIS TEAM TO LEAD ANOTHER PANCREATIC CANCER DREAM TEAM; DR. VON HOFFS SECOND SUCH TEAM (HIS FIRST ACCRUED MORE CANCER PATIENTS ONTO CLINICAL TRIALS THAN ANY DREAM TEAM TO DATE). THIS SELECTION VALIDATES THE SUCCESS THAT DR. VON HOFF AND HIS COLLEAGUES HAVE MADE, AND SIGNIFIES SU2CS BELIEF THAT HIS TEAM OFFERS THE MOST PROMISING NEW APPROACHES TO TREAT PANCREATIC CANCER. THE OVERARCHING AIM FOR THE RESEARCH GRANT IS TO DEVELOP THERAPIES THAT GREATLY IMPROVE A PERSONS SURVIVAL OVER AND ABOVE WHAT DR. VON HOFF AND HIS TEAM HAVE ALREADY ACHIEVED. STAND UP TO CANCER TEAM SCIENCE AWARDS (ALL EXCEEDING 6 MILLION DOLLARS) ARE THE MOST DIFFICULT PEER-REVIEWED SUPPORT TO SECURE IN MEDICAL RESEARCH. DR. JEFFREY TRENT SERVES AS CO-LEADER OF THE MELANOMA DREAM TEAM (JOINTLY SPONSORED BY STAND UP TO CANCER AND THE MELANOMA RESEARCH ALLIANCE). FOR A RESEARCH INSTITUTION TO HAVE TWO OF THE 11 TEAM SCIENCE AWARDS IS A GREAT COMPLIMENT TO THE EXCELLENCE OF TGEN SCIENCE. - THE AVERAGE AGE OF DIAGNOSIS OF OVARIAN CANCER (THE MOST DEADLY FORM OF CANCER IN WOMAN) IS 64 YEARS. BUILDING CLINICALLY ON RESEARCH LED BY TGEN FACULTY, TGEN DEVELOPED A CLINICAL TRIAL FOR PATIENTS FROM AROUND THE WORLD WHO SUFFER FROM THE MOST DEADLY SUB-TYPE OF OVARIAN CANCER, CALLED SMALL CELL CARCINOMA OF THE OVARY (SCCOHT). THIS PARTICULARLY AGGRESSIVE TYPE OF CANCER IS DIAGNOSED AT AN AVERAGE AGE OF 24 YEARS, WITH GIRLS AS YOUNG AS 14 MONTHS DIAGNOSED WITH THIS DISEASE. - ALSO IN A LANDMARK TRIAL, THE SU2C MELANOMA DREAM TEAM DISCUSSED ABOVE (CO-LED BY YALES UNIVERSITIES DR. PAT LORUSSO) ENROLLED ITS FIRST PATIENTS, WITH UP TO ONE HUNDRED MORE PATIENTS WITH THE MOST DEADLY SUB-TYPE OF THIS MELANOMA EXPECTED TO ENROLL OVER THE 18 MONTHS. - WORK SUPPORTED BY THE BEN & CATHERINE IVY FOUNDATION LED TO THREE PROJECTS FOCUSED ON GLIOBLASTOMA. THE FIRST, A SIGNIFICANT AND INNOVATIVE TRIAL WITH COLLEAGUES AT BARROW NEUROLOGICAL INSTITUTE WILL TEST NEW DRUGS IN A PHASE ZERO CLINICAL TRIAL TO DETERMINE IF THEY CAN PENETRATE THE BLOOD-BRAIN BARRIER AND BE EFFECTIVE AGAINST THE TUMOR. ANOTHER DESCRIBED OUR STUDY PUBLISHED IN THE OXFORD UNIVERSITY PRESS JOURNAL NEURO-ONCOLOGY, REVIEWING THE STATE-OF-THE-ART TREATMENTS FOR GLIOBLASTOMA, AND A RELATED CLINICAL TRIAL AT UC SAN FRANCISCO. AND THE THIRD, WORK WITH THE ALLEN BRAIN INSTITUTE IN SEATTLE, WASHINGTON, TO UPDATE THE IVY GLIOBLASTOMA ATLAS PROJECT. - TECHNOLOGY ADVANCEMENTS IN RECENT YEARS NOW ALLOW TGEN AND OTHER SCIENTISTS TO LOOK DEEPER INTO THE HUMAN GENOME THAN EVER BEFORE, WHICH HAS FURTHERED THE RESEARCH OF SEVERAL FACULTY MEMBERS INTO SO-CALLED LIQUID BIOPSIES - MORE OR LESS AN ADVANCED BLOOD TEST - FOR DETECTING THE SMALLEST OF CANCER CELLS (OR THE CONTENT OF THOSE CANCER CELLS) SWIMMING IN A PERSONS BLOOD, LOOKING FOR A SPOT TO TAKE ROOT AND BECOME A FULL-BLOWN TUMOR. - FINALLY, A HOST OF OUR SCIENTISTS INCLUDING DRS. CRAIG AND HUENTLEMAN, JOIN OUR CLINIC LEADER (DR. NARAYANAN) IN THEIR FOCUS ON CHILDREN WITH RARE OR UNDIAGNOSED DISORDERS TO PROVIDE HOPE AND ANSWERS TO PARENTS WHO ENDURE DIAGNOSTIC ODYSSEYS THAT AT TIMES SPANS MULTIPLE YEARS.
PEER-REVIEWED LABORATORY RESEARCH PUBLICATIONS AND PRESENTATIONS	SINCE DAY ONE, THE FOCUS OF OUR TRANSLATIONAL RESEARCH HAS CONSTANTLY REMAINED THE PATIENT; THOSE INDIVIDUALS WITH CANCER, ALZHEIMERS AND OTHER NEUROLOGICAL DISORDERS, AND A HOST OF RARE DISEASES THAT ALL TOO OFTEN GO MIS- OR UNDIAGNOSED. IN JANUARY, DURING HIS STATE-OF-THE-UNION ADDRESS, PRESIDENT OBAMA SAID THAT PERSONALIZED MEDICINE "GIVES US ONE OF THE GREATEST OPPORTUNITIES FOR NEW MEDICAL BREAKTHROUGHS THAT WE HAVE EVER SEEN." WHILE MANY INSTITUTES AND HEALTHCARE NETWORKS HAVE TAKEN UP THE CHARGE OF LATE, TGEN HAS PUSHED THE BOUNDARIES OF THIS SPACE FOR THE PAST DECADE. MUCH OF WHAT WE LEARN IS PUBLISHED IN LEADING SCIENTIFIC AND MEDICAL JOURNALS, WHICH INCREASES THE KNOWLEDGE BASE OF ALL THOSE IN THE BIOMEDICAL RESEARCH AND MEDICAL SPACE. OUR ANNUAL SCIENTIFIC RETREAT IN OCTOBER BROUGHT TOGETHER NEARLY 240 REGISTRANTS INCLUDING TGEN FACULTY, STAFF, STUDENTS AND 45 COLLABORATORS. TGEN SCIENTISTS PRESENTED OVER 60 SCIENTIFIC POSTERS, EIGHT UNIQUE BREAKOUT PANELS AND FOUR COMPETITIVELY SELECTED "HOT TOPICS" PRESENTATIONS. THE PURPOSE OF THE EVENT WAS TO SUMMARIZE THE INSTITUTES SCIENTIFIC YEAR AND CREATE AN ENVIRONMENT IN WHICH NEW PROFESSIONAL RELATIONSHIPS AND COLLABORATIONS, BOTH INTERNAL AND EXTERNAL, COULD DEVELOP. IN 2015, TGEN RESEARCHERS PUBLISHED THEIR RESEARCH RESULTS EXTENSIVELY IN NUMEROUS SCHOLARLY PEER-REVIEWED ACADEMIC JOURNALS AND THROUGH PRESENTATIONS AT LEADING NATIONAL AND INTERNATIONAL CONFERENCES. THESE INCLUDE PUBLICATION IN LEADING SCIENTIFIC JOURNALS SUCH AS SCIENCE ADVANCES, PROCEEDING OF THE NATIONAL ACADEMY OF SCIENCES, USA, CELL, NATURE COMMUNICATIONS, MOLECULAR CANCER THERAPEUTICS, NERO ONCOLOGY, PLOS ONE, GENOME RESEARCH, JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, NEUROLOGY, AND A HOST OF OTHER DISEASE-ASSOCIATED PUBLICATIONS.
2015 SELECT HIGHLIGHTS	A) DESMOPLASIA IN PRIMARY TUMORS AND METASTATIC LESIONS OF PANCREATIC CANCER. CLIFFORD J WHATCOTT, CAROLINE H DIEP, PING JIANG, APRILL WATANABE, JANINE LOBELLO, CHAO SIMA, GALEN HOSTETTER, H. MICHAEL SHEPARD, DANIEL D. VON HOFF, AND HAIYONG HAN. FEBRUARY 18, 2015. B) REVIEW OF X-LINKED SYNDROMES WITH ARTHROGRYPOSIS OR EARLY CONTRACTURES-AID TO DIAGNOSIS AND PATHWAY IDENTIFICATION. HUNTER JM1, KIEFER J, BALAK CD, JOOMA S, AHEARN ME, HALL JG, BAUMBACH-REARDON L. AM J MED GENET A. 2015 MAY; 167(5):931-73. EPUB 2015 MAR 19. C) NOVEL PATHOGENIC VARIANTS AND GENES FOR MYOPATHIES IDENTIFIED BY WHOLE EXOME SEQUENCING. HUNTER JM, AHEARN ME, BALAK CD, LIANG WS, KURDOGLU A, CORNEVEAUX JJ, RUSSELL M, HUENTELMAN MJ, CRAIG DW, CARPTEN JD, COONS SW, DEMELLO DE, HALL JG, BERNES SN AND BAUMBACH-REARDON L. MOLECULAR GENETICS & GENOMIC MEDICINE. VOLUME 3, ISSUE 4, PAGES 283301. ARTICLE FIRST PUBLISHED ONLINE APRIL 8, 2015. D) TOWARDS PRECISION MEDICINE IN GLIOBLASTOMA: THE PROMISE AND THE CHALLENGES. MICHAEL D. PRADOS, SARA A. BYRON, NHAN L. TRAN, JOANNA J. PHILLIPS, ANNETTE M. MOLINARO, KEITH L. LIGON, PATRICK Y. WEN, JOHN G. KUHN, INGO K. MELLINGHOFF, JOHN F. DE GROOT, HOWARD COLMAN, TIMOTHY F. CLOUGHESY, SUSAN M. CHANG, TIMOTHY C. RYKEN, WAIBHAV D. TEMBE, JEFFREY A. KIEFER, MICHAEL E. BERENS, DAVID W. CRAIG, JOHN D. CARPTEN AND JEFFREY M. TRENT. NEURO ONCOL (2015) DOI: 10.1093/NEUONC/NOV031 FIRST PUBLISHED ONLINE: MAY 1, 2015. E) STAPHYLOCOCCUS AUREUS AND THE ECOLOGY OF THE NASAL MICROBIOME. CINDY M. LIU, LANCE B. PRICE, BRUCE A. HUNGATE, ALISON G. ABRAHAM, LISBETH A. LARSEN, KAARE CHRISTENSEN, MARC STEGGER, ROBERT SKOV, PAAL SKYTT ANDERSEN. SCIENCE ADVANCES. 05 JUN 2015, VOL. 1, NO. 5. F) PHYLOGENETICALLY TYPING BACTERIAL STRAINS FROM PARTIAL SNP GENOTYPES OBSERVED FROM DIRECT SEQUENCING OF CLINICAL SPECIMEN METAGENOMIC DATA. SAHL JW, SCHUPP JM, RASKO DA, COLMAN RE, FOSTER JT, KEIM P. GENOME MED. 2015 JUN 9;7(1):52. G) ORCHESTRATING THE TUMOR MICROENVIRONMENT TO IMPROVE SURVIVAL FOR PATIENTS WITH PANCREATIC CANCER: NORMALIZATION, NOT DESTRUCTION. WHATCOTT CJ, HAN H, VON HOFF DD. CANCER J. 2015 JUL-AUG; 21(4): 299-306. H) PILOT TRIAL OF SELECTING MOLECULARLY GUIDED THERAPY FOR PATIENTS WITH NON-V600 BRAF-MUTANT METASTATIC MELANOMA: EXPERIENCE OF THE SU2C/MRA MELANOMA DREAM TEAM. LORUSSO PM, BOERNER SA, PILAT MJ, FORMAN KM, ZUCCARO CY, KIEFER JA, LIANG WS, HUNSBERGER S, REDMAN BG, MARKOVIC SN, SEKULIC A, BRYCE AH, JOSEPH RW, COWEY CL, FECHER LA, SOSMAN JA, CHAPMAN PB, SCHWARTZ GK, CRAIG DW, CARPTEN JD, TRENT JM. MOL CANCER THER. 2015 AUG; 14(8): 1962-71. EPUB 2015 JUN 10. I) WHOLE-GENOME BISULFITE SEQUENCING OF CELL-FREE DNA IDENTIFIES SIGNATURE ASSOCIATED WITH METASTATIC BREAST CANCER. LEGENDRE C, GOODEN GC, JOHNSON, MARTINEZ RA, LIANG WS AND SALHIA B. CLINICAL EPIGENETICS 2015, 7:100. SEPTEMBER 16, 2015. J) BRINGING RNA-SEQ CLOSER TO THE CLINIC. VAN KEUREN-JENSEN K, KEATS JJ, CRAIG DW. NAT BIOTECHNOL. 2014 SEP; 32(9):884-5. K) MULTIFOCAL CLONAL EVOLUTION CHARACTERIZED USING CIRCULATING TUMOR DNA IN A CASE OF METASTATIC BREAST CANCER. MUHAMMED MURTAZA, SARAH-JANE DAWSON, KATHERINE POGREBNIAK, OSCAR M. RUEDA, ELENA PROVENZANO, JOHN GRANT, SUET-FEUNG CHIN, DANA W. Y. TSUI, FRANCESCO MARASS, DAVINA GALE, H. RAZA ALI, PANKTI SHAH, TANIA CONTENTE-CUOMO, HOSSEIN FARAHANI, KAREY SHUMANSKY, ZOYA KINGSBURY, SEAN HUMPHRAY, DAVID BENTLEY, SOHRAB P. SHAH, MATTHEW WALLIS, NITZAN ROSENFELD & CARLOS CALDAS. NATURE COMMUNICATIONS 6, ARTICLE NUMBER: 8760. L) RARE VARIANTS IN CARDIOMYOPATHY GENES ASSOCIATED WITH STRESS-INDUCED CARDIOMYOPATHY. KALANI MY, SINIARD AL, CORNEVEAUX JJ, BRUHNS R, RICHHOLT R, FORSETH J, ZABRAMSKI JM, NAKAJI P, SPETZLER RF, HUENTELMAN MJ. NEUROSURGERY. 2015 NOV 24.
GRANT SUPPORT	IN ADDITION TO PHILANTHROPIC DONATIONS AND RESEARCH CONTRACTS, GRANT FUNDING IS AN IMPORTANT FUNDING SOURCE FOR RESEARCH. TO DATE IN 2015, TGEN INVESTIGATORS SUBMITTED 97 GRANTS TOTALING $84M. TO DATE IN 2015, TGEN WAS AWARDED 20 GRANTS, TOTALING $5.7M, WITH AN ADDITIONAL 12 GRANTS PENDING AWARD TOTALING $3.6M AND 54 GRANTS UNDER REVIEW TOTALING $35M. TGENS SUCCESS RATE HAS CONSISTENTLY MET OR EXCEEDED THE NATIONAL AVERAGE AS CALCULATED BY THE NIH. IN 2015, TGENS CUMULATIVE SUCCESS RATE OF 22%, WAS SLIGHTLY HIGHER THAN THE NATIONAL AVERAGE. 2015 highlights A SELECTION OF AWARDS INCLUDE: A) THREE-YEAR STAND UP TO CANCER GRANT TOTALING $12M TO DR. VON HOFF TO DEVELOP THERAPIES THAT IMPROVE SURVIVAL OF PATIENTS WITH PANCREATIC CANCER. B) FIVE-YEAR GRANT FROM THE NATIONAL INSTITUTES OF HEALTH TOTALING $1,665,818 TO DR. MATT HUENTELMAN TO STUDY NEURAL SYSTEM DYNAMICS AND GENE EXPRESSION SUPPORTING SUCCESSFUL COGNITIVE AGING. C) FIVE-YEAR GRANT FROM NIH TOTALING $778,502 TO DR. MATT HUENTELMAN TO STUDY EPIGENETIC, NEUROIMAGING AND BEHAVIORAL EFFECTS OF HYPERTENSION IN THE AGING BRAIN. D) TWO-YEAR GRANT FROM THE NATIONAL INSTITUTES OF HEALTH TOTALING $735,851 TO DR. PATRICK PIRROTTE TO STUDY PRESERVATION OF DRIED PLASMA SPOTS FOR DOWNSTREAM PROTEOMIC APPLICATIONS. E) FOUR-YEAR GRANT FROM NIH TOTALING $471,542 TO DR. MATT HUENTELMAN TO STUDY A CELL ACTIVITY TAGGING TOOLBOX, ALSO KNOW AS CATT, TO BETTER UNDERSTAND DEVELOPMENT AND APPLICATION OF NEURONAL CELL ACTIVITY. F) ONE-YEAR GRANT FROM THE CENTERS FOR DISEASE CONTROL AND PREVENTION TOTALING $339,997 TO DR. PAUL KEIM TO STUDY DNA SEQUENCING AND BIOINFORMATICS ANALYSIS OF PATHOGENS WITH IMP. G) ONE-YEAR GRANT FROM THE ARIZONA BIOMEDICAL RESEARCH COMMISSION TOTALING $225,000 TO DR. JESSE HUNTER TO STUDY IDENTIFICATION AND FUNCTIONAL CHARACTERIZATION OF NOVEL NEUROMUSCULAR DISEASE CAUSING VARIANTS IN ARIZONA INFANTS AND CHILDREN. H) TWO-YEAR GRANT FROM THE AVON FOUNDATION TOTALING $200,006 TO DR. BODOUR SALHIA TO STUDY THE DEVELOPMENT OF NOVEL TARGETED THERAPEUTIC APPROACHES FOR BREAST CANCER METASTASIS TO THE BRAIN. I) TWO-YEAR GRANT FROM SCIENCE FOUNDATION ARIZONA TOTALING $200,000 TO DR. JEFFREY TRENT ON BEHALF OF DR. MUHAMMAD MURTAZA TO STUDY THE FUTURE OF TRANSLATIONAL RESEARCH. J) TWO-YEAR GRANT FROM THE NATIONAL INSTITUTES OF HEALTH TOTALING $176,403 TO DR. DAVID CRAIG TO STUDY SOMATIC MUTATIONS IN THE BRAIN DURING ALZHEIMERS DISEASE. K) TWO-YEAR GRANT FROM THE DEPARTMENT OF DEFENSE TOTALING $73,654 TO DR. KENDALL VAN-KEUREN JENSEN TO STUDY EXOSOME-MEDIATED TRANSMISSION OF NEURODEGENERATION IN AMYOTROPHIC LATERAL SCLEROSIS (ALS). L) TWO-YEAR GRANT FROM THE NATIONAL FOUNDATION FOR CANCER RESEARCH TOTALING $300,002 TO DRS. DANIEL VON HOFF AND HAIYONG HAN TO STUDY A NOVEL APPROACH TO TARGETING CANCER CELLS THROUGH MODULATING GLOBAL GENE TRANSCRIPTION USING SUPER-ENHANCER (SE) INHIBITORS. M) ONE-YEAR GRANT FROM THE ARIZONA ALZHEIMERS RESEARCH CONSORTIUM TOTALING $205,000 TO DR. MATT HUENTELMAN FOR FOUR PROJECTS INVOLVING "EXCEPTIONAL" PHENOTYPES, THE DYRK1A GENE, VALIDATION OF RNA TARGETS IN SERUM AND CSF AND CHARACTERIZATION OF MITOCHONDRIAL PSEUDOGENES IN ALZHEIMERS DISEASE. N) THREE-YEAR GRANT FROM THE NATIONAL INSTITUTES OF HEALTH (NIH) TOTALING $2,062,360 TO DR. KENDALL VAN KEUREN-JENSEN AND DR. MATT HUENTELMAN FOR A STUDY OF BIOMARKERS THAT COULD PREDICT PATIENT OUTCOMES, FOLLOWING INJURIES THAT RESULT IN BLEEDING IN THE BRAIN. O) FIVE-YEAR GRANT FROM NIH TOTALING $1,033,331 TO DR. NHAN TRAN TO STUDY THE NOVEL ROLE OF TROY-EGFR GENE COMPLEX IN GLIOBLASTOMA BRAIN TUMOR INVASION AND RESISTANCE. P) TWO-YEAR GRANT FROM THE NIH TOTALING $487,540 TO DR. MATT HUENTELMAN FOR A STUDY IDENTIFYING PATHOGENIC MECHANISMS IMPORTANT IN MULTIPLE SYSTEM ATROPHY (MSA), FOR WHICH THERE CURRENTLY ARE NO DISEASE PREVENTING OR MODIFYING TREATMENTS. Q) TWO-YEAR GRANT FROM NIH/NATIONAL CANCER INSTITUTE TOTALING $445,005 TO DR. HAIYONG HAN FOR A STUDY TARGETING THE PHD2 GENE IN PANCREATIC CANCER. R) ONE-YEAR GRANT FROM THE CENTERS FOR DISEASE CONTROL TOTALING $347,043 TO DR. PAUL KEIM FOR DNA SEQUENCING AND BIOINFORMATICS ANALYSIS OF PATHOGENS, INCLUDING EMERGENCY RESPONSE AS NEEDED FOR DISEASE OUTBREAK.
ENTERPRISE EFFORTS, COLLABORATION, SPIN-OFFS AND JOB CREATION	THE TECHNOLOGY TRANSFER OFFICE (TTO) FACILITATES AND ACCELERATES THE COMMERCIALIZATION OF TGEN'S SCIENTIFIC DISCOVERIES FOR THE BENEFIT OF HUMAN HEALTH BY, - IDENTIFYING, PATENTING AND LICENSING NEW TECHNOLOGY; - FACILITATING ACCESS AND EXCHANGE OF RESEARCH MATERIALS, TECHNOLOGIES, AND DATA VIA MATERIAL TRANSFER AGREEMENTS (MTAS) OR CONFIDENTIAL DISCLOSURE AGREEMENTS (CDAS); - NEGOTIATING COLLABORATIVE RESEARCH AGREEMENTS; AND - ASSISTING IN THE FORMATION OF START-UP COMPANIES WHEN APPROPRIATE. DURING 2015, TGEN CONTINUED COLLABORATIONS WITHIN THE STATE OF ARIZONA, INCLUDING NEW JOINT FACULTY WITH MAYO CLINIC. Invention disclosures TGEN RECEIVED 18 INVENTION DISCLOSURES BASED ON DISCOVERIES STEMMING FROM TGEN-LED RESEARCH, AND FILED 19 PROVISIONAL PATENT APPLICATIONS. Contracts and collaborations TGEN SIGNED A TOTAL OF 358 CONTRACTS/AMENDMENTS IN 2015, BROKEN DOWN AS FOLLOWS: A) 65 CDAS B) 66 MTAS C) 18 RESEARCH COLLABORATIONS D) 15 MASTER RESEARCH/SERVICES AGREEMENTS E) 44 RESEARCH PLANS AND SOWS F) 23 CONSULTING AGREEMENTS G) 62 PROFESSIONAL SERVICE AGREEMENTS H) 02 COMMERCIALIZATION LICENSES I) 63 AGREEMENTS COVERING MISCELLANEOUS ACTIVITIES A LISTING OF A NUMBER OF THE MAJOR RESEARCH COLLABORATORS INCLUDE: ALLINA HEALTH/JNNI; BAYLOR RESEARCH INSTITUTE; BROAD INSTITUTE; COLORADO STATE UNIVERSITY; DIGNITY; FLORIDA INSTITUTE FOR HUMANE & MACHINE COGNITION; GEORGE MASON UNIVERSITY; HONORHEALTH; MAYO CLINIC; MIDWESTERN UNIVERSITY; NATIONAL CENTER FOR ADVANCING TRANSLATION SCIENCES; OHIO STATE UNIVERSITY; ST. ANNES UNIVERSITY HOSPITAL. Job creation IN 2015, 21 NEW FULL-TIME EQUIVALENT POSITIONS WERE CREATED WITH SALARIES AND BENEFITS TOTALING $1,205,184. SALARIES FOR TEMPORARY POSITIONS (THOSE POSITIONS CREATED FOR A FINITE PERIOD OF TIME) TOTALED $99,120, WHICH INCLUDES TEMPORARY TGEN STAFF AND TEMPORARY SERVICE FEES. STUDENT SALARIES WERE JUST OVER $460,000, BRINGING THE OVERALL 2015 TOTAL TO $1,665,184. IN TERMS OF EDUCATION LEVEL, EIGHTY-SIX PERCENT OF FULL-TIME TGEN STAFF HOLDS A COLLEGE DEGREE AND FIFTY PERCENT HOLDS AN ADVANCED DEGREE. 2015 FULL-TIME POSITIONS FILLED (NEW AND REPLACEMENTS) INCLUDED: - ASSOCIATE BIOINFORMATICIAN - ASSISTANT PROFESSOR - BIOINFORMATICIAN - CLINICAL RESEARCH COORDINATOR - FINANCIAL ANALYST II - CONTRACTS MANAGER - FACILITIES TECHNICIAN - POST-DOC FELLOW - RESEARCH ASSISTANT PROFESSOR - RESEARCH ASSOCIATE - RESEARCH ASSOCIATE II - RESEARCH TECHNICIAN - SR. GRANTS ADMINISTRATOR - SR. STAFF SCIENTIST - SR. VICE PRESIDENT, EMERGING OPPORTUNITIES
EDUCATION	TGEN DESIGNED ITS SCIENCE EDUCATION AND COMMUNITY OUTREACH INITIATIVES TO ASSIST IN THE GROWTH OF THE BIOSCIENCE WORKFORCE IN ARIZONA, INCREASE PUBLIC FLUENCY IN TRANSLATIONAL MEDICINE, AND BUILD AN ACCESSIBLE COMMUNITY PRESENCE. 2015 HIGHLIGHTS INCLUDE: NEARLY 600 ARIZONA STUDENTS APPLIED TO THE 2015 HELIOS SCHOLARS AT TGEN PROGRAM, WITH 45 SELECTED TO WORK FULL-TIME ALONGSIDE A TGEN MENTOR TO DEVELOP AND ENHANCE THEIR SKILLS BY CONTRIBUTING TO AN AUTHENTIC BIOMEDICAL RESEARCH PROJECT. IN TERMS OF 2015 COHORT DEMOGRAPHICS, 69 PERCENT ATTEND COLLEGES OR UNIVERSITIES IN ARIZONA; 27 PERCENT SELF-IDENTIFY AS RACES/ETHNICITIES UNDERREPRESENTED IN THE BIOSCIENCES; 11 PERCENT ATTEND HIGH SCHOOL, 87 PERCENT ARE WORKING TOWARD AN UNDERGRADUATE DEGREE AND 2 PERCENT ATTEND GRADUATE OR MEDICAL SCHOOL. TGEN ENGAGED OVER 60 HELIOS SCHOLARS ALUMNI FOR THE FOURTH ANNUAL ALUMNI NETWORKING RECEPTION. ALUMNI PROVIDED GUIDANCE TO THIS SUMMERS INTERN CLASS VIA A PANEL DISCUSSION AND PARTICIPATED IN THE SELECTION PROCESS. NETWORKING OPPORTUNITIES ENSURE THE PROGRAM CONTINUES TO DELIVER ON THE MISSION TO GROW THE BIOSCIENCE WORKFORCE IN ARIZONA. THE 2015-2016 IVY NEUROLOGICAL SCIENCES INTERNSHIP PROGRAM BEGAN IN JUNE. TWO HIGH SCHOOL STUDENTS COMPLETED BRAIN TUMOR AND NEUROLOGICAL DISEASE RESEARCH INTERNSHIPS IN JULY. TWO UNDERGRADUATES AND ONE MEDICAL SCHOOL STUDENT WILL BEGIN IN SEPTEMBER. AT THE CONCLUSION OF THIS YEARS PROGRAM, 22 ARIZONA STUDENTS WILL HAVE COMPLETED PROFESSIONAL DEVELOPMENT AND INTENSIVE RESEARCH TRAINING IN BRAIN TUMORS AND NEUROLOGICAL DISEASE. THE PROGRAM CONTINUES TO BE A HIGH-CALIBER SUCCESS IN WORKFORCE DEVELOPMENT AND PRODUCTIVE RESEARCH, RESULTING FROM THE GENEROSITY OF THE BEN AND CATHERINE IVY FOUNDATION. IN ADDITION TO ITS ANNUAL HELIOS SCHOLARS AND IVY PROGRAMS, TGEN BROADENED THE SCOPE OF DIVERSITY IN STUDENT INTERN EXPERIENCES BY HOSTING A STUDENT INTERN FROM A PUBLIC AND HISTORICALLY BLACK UNIVERSITY, NORTH CAROLINA CENTRAL UNIVERSITY, PART OF THE UNIVERSITY OF NORTH CAROLINA SYSTEM. ADDITIONALLY, TGEN RESEARCHERS MENTORED TWO BASIS SCHOOLS STUDENTS, AND HOSTED THREE ACADEMIC YEAR INTERNS SUPPORTED BY ARIZONA COMMUNITY FOUNDATION FUNDING. WITH AN AWARD OF $25,000 FROM THE SCOTTSDALE UNIFIED SCHOOL DISTRICT FOUNDATION, TGEN CONDUCTED A TEACHER TRAINING PILOT PROGRAM IN JULY WITH SAGUARO HIGH SCHOOL, A MAGNET MATH AND SCIENCE ACADEMY IN THE SCOTTSDALE UNIFIED SCHOOL DISTRICT. THE PURPOSE OF THE THREE-DAY, FIVE-TEACHER PROGRAM WAS TO INCREASE THE TEACHERS CONTENT KNOWLEDGE, DEPTH OF UNDERSTANDING AND INSIGHT INTO BIOMEDICAL RESEARCH, BENEFITTING AN EXPONENTIAL NUMBER OF ARIZONA STUDENTS OVER TIME. AN INTENSIVE AGENDA IMMERSED TEACHERS IN A SERIES OF PRESENTATIONS, INTERACTIVE DISCUSSIONS AND PRACTICAL EXPERIENCES LED BY TGEN FACULTY AND STAFF. THE PROGRAM PROVIDED PROOF-OF-CONCEPT FOR THE POSSIBILITY OF A FUTURE STATEWIDE TEACHER PROFESSIONAL DEVELOPMENT INITIATIVE THAT WILL ENHANCE TGENS REPUTATION AS A COMMITTED EDUCATION STAKEHOLDER IN ARIZONA. PROGRAM FEEDBACK WAS OVERWHELMINGLY POSITIVE. TGEN ASSISTED THE FLINN FOUNDATION WITH PILOTING A NEW INTERNSHIP PROGRAM AS PART OF ITS WORKFORCE DEVELOPMENT INITIATIVE, THE FLINN SCHOLARS PROGRAM. AN ARIZONA STATE UNIVERSITY FLINN SCHOLAR FOCUSED ON THE BUSINESS OF SCIENCE WORKING ALONGSIDE TGENS BUSINESS DEVELOPMENT TEAM. TGEN STAFF TRAVELED TO PITTSBURGH TO VOLUNTEER AND COLLECT DATA AT THE 2015 INTEL ISEF, THE INTERNATIONAL HIGH SCHOOL SCIENCE FAIR, WHICH IS THE LARGEST IN THE WORLD. THE INTEL ISEF WILL RETURN TO PHOENIX IN 2016 AND 2019. TGEN STAFF PARTICIPATES ON THE LOCAL ARRANGEMENTS COMMITTEE AND JUDGE RECRUITMENT COMMITTEE TO ENSURE THE THOUSANDS OF INDIVIDUALS ATTENDING THE FAIR FROM NEARLY 70 COUNTRIES EXPERIENCE PHOENIX AND TGEN IN A POSITIVE WAY. LASTLY, TGEN STAFF PARTICIPATED IN AN UPDATE OF THE BIOSCIENCE STANDARDS FOR THE ARIZONA DEPARTMENT OF EDUCATION CAREER AND TECHNICAL EDUCATION VIA THE VALIDATION COMMITTEE. THE GOAL OF PARTICIPATION WAS TO PROVIDE EXPERT INSIGHT INTO THE TECHNICAL KNOWLEDGE AND SKILLS HIGH SCHOOL STUDENTS NEED TO BE PREPARED TO ENTER THE BIOSCIENCE WORKFORCE.
PUBLIC OUTREACH	IN 2015, TGEN HOSTED OVER 800 INDIVIDUALS FOR LABORATORY TOURS, AN INCREASE OF NEARLY 40 PERCENT OVER 2014. TGEN IS COMMITTED TO MAINTAINING AN ACCESSIBLE COMMUNITY PRESENCE FOR THE PUBLIC, SCHOOL GROUPS, LEADERS AND INTERESTED INDIVIDUALS. TGEN BELIEVES IT HAS A RESPONSIBILITY TO OFFER WORKFORCE DEVELOPMENT KNOWLEDGE, CONTENT AND EXPERTISE TO OUR EDUCATION COMMUNITY PARTNERS. IN THIS SPIRIT, TGEN IS REPRESENTED ON BOARDS, COMMITTEES AND WORKING GROUPS INCLUDING, BUT NOT LIMITED TO: CENTER FOR RESEARCH IN ENGINEERING, SCIENCE AND TECHNOLOGY (CREST) SCHOOL ADVISORY BOARD; ARIZONA BIOINDUSTRY ASSOCIATION EVENTS AND EDUCATION COMMITTEE; CITY OF PHOENIX HEALTHCARE SECTOR PARTNERSHIP; ARIZONA BIOMEDICAL RESEARCH COMMISSION; CENTRAL PHOENIX WOMEN; DEER VALLEY UNIFIED SCHOOL DISTRICT CAREER AND TECHNICAL EDUCATION BOARD; TEMPE UNIFIED HIGH SCHOOL DISTRICT CAREER AND TECHNICAL EDUCATION BOARD; QUEEN CREEK HIGH SCHOOL BIOTECHNOLOGY ADVISORY PANEL; PEORIA UNIFIED MEDICAL, ENGINEERING AND TECHNOLOGY PROFESSIONAL ACADEMY ADVISORY TEAM. IN MARCH 2015, TGEN HOSTED TWO PHOENIX HIGH SCHOOL STUDENTS FOR THE BE A LEADER FOUNDATIONS ANNUAL SHADOW A PROFESSIONAL DAY. TGEN HAS PARTICIPATED IN THIS EVENT EVERY YEAR FOR MORE THAN FIVE YEARS. THE MISSION OF THE BE A LEADER FOUNDATION IS TO DESIGN PROGRAMS THAT INSTILL A HIGH SCHOOL COMPLETION AND COLLEGE-GOING CULTURE FOR LOCAL STUDENTS. IN SUPPORT OF THE ARIZONA SCITECH FESTIVAL, TGEN PARTNERED WITH START@WEST-MEC, A COLLABORATIVE EDUCATION SPACE AT THE WESTERN MARICOPA EDUCATION CENTER, TO DELIVER TEACHER PROFESSIONAL DEVELOPMENT IN BIOINFORMATICS AND COMPUTATIONAL BIOLOGY. TGEN SELECTED THIS PARTNER TO INCREASE ACCESS TO TGEN PROFESSIONAL DEVELOPMENT FOR WEST VALLEY EDUCATORS. ABOUT 20 TEACHERS ATTENDED TO INTERACT WITH A PANEL OF TGEN RESEARCHERS AND STUDENT INTERNS.
MEDIA, MARKETING AND PUBLIC RECOGNITION	THE OVERALL GOAL OF TGENS MEDIA EFFORTS IS TO BUILD A STRONG AND COMPELLING COMMUNICATIONS TOOL SET TO TELL TGENS STORY IMMEDIATELY TO AUDIENCES THAT, OVER TIME, WILL BE INCREASINGLY AWARE OF TGEN AND WHAT MAKES IT UNIQUE AND ESSENTIAL. TO THE END, TGEN CONTINUALLY PURSUES EARNED MEDIA EXPOSURE FOR THE INSTITUTES RESEARCH ACTIVITIES. 2015 ALSO MARKED TGENS ENGAGEMENT IN PAID MEDIA TO DRIVE TRAFFIC THROUGH ITS VARIOUS SOCIAL CHANNELS. IN TERMS OF OUR SOCIAL PLATFORMS, WE SAW A 27.5% INCREASE ON FACEBOOK; 34.5% ON TWITTER; 94.5% ON LINKEDIN, AND OUR E-NEWS IS NOW SENT TO OVER 12,000 SUBSCRIBERS/DONORS. OUR EARNED MEDIA EFFORTS CONTINUE TO RECEIVE POSITIVE PRESS, BOTH LOCALLY AND NATIONALLY, TOTALING NEARLY 1,000 IMPRESSIONS ACROSS VARIOUS PRINT, BROADCAST AND DIGITAL PLATFORMS, INCLUDING: FORBES MAGAZINE, NEWSWEEK, THE ARIZONA REPUBLIC, PITTSBURGH POST-GAZETTE, SAN ANGELO STANDARD-TIMES (TEXAS), GENOMEWEB, PHOENIX BUSINESS JOURNAL, ARIZONA BUSINESS GAZETTE, THE ARIZONA DAILY SUN (FLAGSTAFF), ABC 15, FOX 10, CBS 5, ARIZONA FAMILY CHANNEL 3, KJZZ, KFYI, KTAR, CHANNEL 8 PBS PHOENIX, CHANNEL 6 PBS TUCSON, ARIZONA REDBOOK, ARIZONA FOOTHILLS MAGAZINE, ARIZONAS VOICE, MAGAZINE, DRUG DELIVERY: SURVEYING THE GLOBAL COMPETITIVE LANDSCAPE, STATES NEWS SERVICE, TARGETED NEWS SERVICE, PLUS PATENT NEWS, PRWEB NEWSWIRE, WEB NEWSWIRE, VIRTUAL STRATEGY MAGAZINE, US FED NEWS, US OFFICIAL NEWS. IN TERMS OF PUBLIC RECOGNITION, TGEN FACULTY AND LEADERSHIP PARTICIPATED IN NUMEROUS COMMUNITY ACTIVITIES AND SERVE ON MANY BOARDS. RECOGNITION OF TGENS EFFORTS SERVES TO HIGHLIGHT OUR PUBLIC, ACADEMIC AND INDUSTRY INVOLVEMENT ACROSS ARIZONA. IN 2015, RECOGNITION INCLUDED: IN MARCH, THE PHOENIX BUSINESS JOURNAL NAMED TGEN COO TESS BURLESON AS ONE OF THE PHOENIX BUSINESS JOURNALS 2015 OUTSTANDING WOMEN IN BUSINESS. THE AWARD HONORS REMARKABLE WOMEN IN THE VALLEY BUSINESS COMMUNITY WHO SERVE AS MENTORS, LEADERS AND VISIONARIES. TGEN ASSOCIATE PROFESSOR DR. MATT HUENTELMAN DELIVERED THE KEYNOTE PRESENTATION AT THE ANNUAL ARIZONA BIOINDUSTRY ASSOCIATION EXPO IN APRIL. DR. HUENTELMAN DISCUSSED HOW TGEN'S MINDCROWD PROGRAM IS A PRIME EXAMPLE OF USING ONLINE CROWDSOURCING TO RECRUIT VOLUNTARY INDIVIDUALS FOR SCIENTIFIC STUDIES AND CLINICAL RESEARCH TO AN AUDIENCE OF BIOSCIENCE INDUSTRY LEADERS, STATE AND CITY OFFICIALS AND STUDENTS. TGEN DIRECTOR OF PUBLIC AFFAIRS AND EDUCATION, BRANDY WELLS, WAS APPOINTED BY GOVERNOR DOUG DUCEY TO THE ARIZONA BIOMEDICAL RESEARCH COMMISSION AND CONFIRMED BY THE ARIZONA SENATE TO SERVE A THREE-YEAR TERM AS A PUBLIC MEMBER COMMISSIONER.
FORM 990, PART V, LINE 2A; PART VII, SECTION A; AND PART IX	TGEN FOUNDATION DOES NOT HAVE EMPLOYEES, BUT SHARES THE COST OF PERSONNEL, SERVICES, FACILITIES AND EXPENSES WITH TGEN, A RELATED TAX-EXEMPT ORGANIZATION.
FORM 990, PART VI, LINE 1A	TO THE EXTENT ALLOWED BY LAW, THE EXECUTIVE COMMITTEE MAY ACT ON TGEN FOUNDATION'S BEHALF IN ANY MATTER WHEN THE BOARD OF DIRECTORS IS NOT IN SESSION, REPORTING TO THE BOARD OF DIRECTORS FOR ITS INFORMATION AT THE NEXT SUBSEQUENT REGULAR OR SPECIAL MEETING OF THE BOARD. THE EXECUTIVE COMMITTEE CONSISTS OF THE DESIGNATED DIRECTORS, THE CHAIRPERSON OF THE BOARD AND UP TO THREE OTHER FOUNDATION DIRECTORS AS SHALL BE DESIGNATED BY THE BOARD OF DIRECTORS.
FORM 990, PART VI, LINE 6	THE SOLE CORPORATE MEMBER OF TGEN FOUNDATION IS THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (TGEN).
FORM 990, PART VI, LINE 7A	TGEN, AS THE SOLE CORPORATE MEMBER OF TGEN FOUNDATION, HAS THE RIGHT TO ELECT THE BOARD OF DIRECTORS OF TGEN FOUNDATION.
FORM 990, PART VI, LINE 7B	THE SOLE CORPORATE MEMBER'S VOTE SHALL BE REQUIRED ON: A) THE ELECTION AND REMOVAL OF ELECTED DIRECTORS AS SET FORTH IN THE BYLAWS; B) THE ADOPTION OF ANY PLAN OF MERGER OR CONSOLIDATION; C) THE SALE OF ALL OR SUBSTANTIALLY ALL THE FOUNDATION'S ASSETS IN A SINGLE TRANSACTION OR SERIES OF RELATED TRANSACTIONS; D) THE AMENDMENT OF THE FOUNDATION'S ARTICLES OF INCORPORATION OR BYLAWS; E) THE INSTITUTION, OR CONSENT TO INSTITUTION, OF PROCEEDINGS TO ADJUDICATE THE FOUNDATION BANKRUPT OR INSOLVENT, OR THE FILING OF A PETITION SEEKING OR CONSENTING TO REORGANIZATION OR RELIEF UNDER ANY LAW RELATING TO BANKRUPTCY, INSOLVENCY, OR OTHER RELIEF FOR DEBTORS, OR THE CONSENT TO THE APPOINTMENT OF A RECEIVER, LIQUIDATOR, ASSIGNEE, TRUSTEE, SEQUESTRATOR (OR SIMILAR OFFICIAL) OF THE FOUNDATION OR OF ALL OR ANY SUBSTANTIAL PART OF ITS PROPERTY, OR THE MAKING OF ANY ASSIGNMENT FOR THE BENEFIT OF CREDITORS, OR THE ADMISSION IN WRITING OF THE FOUNDATION'S INABILITY TO PAY ITS DEBTS GENERALLY AS THEY BECOME DUE, OR ANY STEPS IN FURTHERANCE OF SUCH ACTIONS; AND F) THOSE MATTERS UPON WHICH THE MEMBER IS GRANTED VOTING RIGHTS IN THE ARTICLES OF INCORPORATION, BYLAWS, OR THE ARIZONA NONPROFIT CORPORATION ACT. THE SOLE CORPORATE MEMBER HAS THE FOLLOWING RESERVE POWERS: A) APPOINT AND REMOVE THE PRESIDENT; B) APPROVE THE ESTABLISHMENT OF NEW CORPORATE PARTNERSHIP ENTITIES CREATED OR JOINED BY THE FOUNDATION; C) APPROVE THE FOUNDATION'S EXECUTION OF MATERIAL CONTRACTS; AND D) APPROVE THE FOUNDATION'S INCURRENCE OF MATERIAL DEBTS.
FORM 990, PART VI, LINE 11B	THE FORM 990 IS PREPARED BY AN OUTSIDE ACCOUNTING FIRM BASED ON INFORMATION PROVIDED BY THE TGEN FINANCE DEPARTMENT. THE FORM 990 IS THEN REVIEWED BY THE FINANCE DEPARTMENT AND OTHER MEMBERS OF MANAGEMENT. THE FORM 990 IS POSTED ON THE BOARD WEBSITE FOR BOARD REVIEW PRIOR TO FILING WITH THE IRS.
FORM 990, PART VI, LINE 12C	TGEN FOUNDATION DISTRIBUTES A CONFLICT OF INTEREST QUESTIONNAIRE ANNUALLY TO ALL DIRECTOR LEVEL POSITIONS AND ABOVE, IN ADDITION TO ANY KEY EMPLOYEES DESIGNATED BY THE TGEN CHIEF OPERATING OFFICER. THE QUESTIONNAIRES ARE REVIEWED BY THE TGEN CHIEF FINANCIAL OFFICER AND TGEN'S OFFICE OF RESEARCH COMPLIANCE. THOSE EMPLOYEES WITH CONFLICTS ARE SENT FOR FURTHER REVIEW TO THE TGEN CHIEF OPERATING OFFICER TO ENSURE AN APPROPRIATE PLAN IS SET FORTH. UPDATES TO THE LIST ARE HANDLED ON AN AS-NEEDED BASIS, BASED ON CONTRACT REVIEWS AND EMPLOYEE INFORMATION.
FORM 990, PART VI, LINES 15A AND 15B	THE FOUNDATION DOES NOT HAVE ANY DIRECT EMPLOYEES. COMPENSATION IS DETERMINED BY THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (TGEN) USING THE FOLLOWING PROCESS: TGEN'S GOVERNANCE AND EXECUTIVE COMPENSATION COMMITTEE WILL ACT IN AN "ADVICE AND CONSENT" CAPACITY REVIEWING THE RECOMMENDATIONS FOR THE PRESIDENT AND SCIENTIFIC DIRECTOR REGARDING THE COMPENSATION OF DISQUALIFIED PERSONS AND FORWARDING FINAL RECOMMENDATIONS TO THE FULL BOARD FOR APPROVAL. DISQUALIFIED PERSONS (EXCEPT FOR THE PRESIDENT AND SCIENTIFIC DIRECTOR) WILL NOT BE PRESENT FOR, OR PARTICIPATE IN, COMMITTEE DELIBERATIONS CONCERNING THEIR COMPENSATION (OTHER THAN TO ANSWER QUESTIONS). THE PRESIDENT AND SCIENTIFIC DIRECTOR WILL PARTICIPATE IN THE DELIBERATIONS CONCERNING THE COMPENSATION OF DIRECT REPORTS. DURING THE DECISION MAKING PROCESS, THE COMMITTEE WILL ADHERE TO THE EXECUTIVE COMPENSATION PHILOSOPHY. THE COMMITTEE IS AUTHORIZED (AND PROVIDED WITH SUFFICIENT FUNDING) TO ANNUALLY ENGAGE OUTSIDE INDEPENDENT COMPENSATION AND LEGAL ADVISORS, WHEN DEEMED NECESSARY AND ADVISABLE. THE COMMITTEE WILL COMPLY WITH THE "REBUTTABLE PRESUMPTION OF REASONABLENESS" UNDER SECTION 4958 OF THE INTERNAL REVENUE CODE WHENEVER POSSIBLE. THE COMMITTEE WILL REVIEW AND UNDERSTAND THE INTERNAL REVENUE CODE PROVISIONS DEALING WITH "EXCESS BENEFIT TRANSACTIONS CONCERNING DISQUALIFIED PERSONS' COMPENSATION." WHEN DEVELOPING A COMPENSATION PHILOSOPHY, TGEN KEPT IN MIND THE FOLLOWING FACTORS: THE TGEN MISSION AND STRATEGY THE TGEN CULTURE TRENDS IN COMPENSATION IN THE EXTERNAL ENVIRONMENT TRENDS IN RECRUITMENT OF NEW EMPLOYEES TRENDS IN ORGANIZATIONAL EMPLOYEE TURNOVER TGEN'S LIFE CYCLE STAGE THE COMPENSATION REVIEW PROCESS WAS LAST COMPLETED IN 2015.
FORM 990, PART VI, LINE 19	TGEN FOUNDATION PROVIDES ITS GOVERNING DOCUMENTS AND CONFLICT OF INTEREST POLICY TO THE GENERAL PUBLIC UPON REQUEST.

For Paperwork Reduction Act Notice, see the Instructions for Form 990 or 990-EZ.

Cat. No. 51056K

Schedule O (Form 990 or 990-EZ) 2015

Additional Data

Software ID:
Software Version:

- TIN:

SCHEDULE R
(Form 990)

Department of the Treasury
Internal Revenue Service

Related Organizations and Unrelated Partnerships

Complete if the organization answered "Yes" on Form 990, Part IV, line 33, 34, 35b, 36, or 37.
MediumBullet

Attach to Form 990.
MediumBullet

Information about Schedule R (Form 990) and its instructions is at www.irs.gov/form990.

OMB No. 1545-0047

2015

Open to Public Inspection

Name of the organization

THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE
FOUNDATION

Employer identification number

33-1092191

Part I

Identification of Disregarded Entities Complete if the organization answered "Yes" on Form 990, Part IV, line 33.

(a) Name, address, and EIN (if applicable) of disregarded entity	(b) Primary activity	(c) Legal domicile (state or foreign country)	(d) Total income	(e) End-of-year assets	(f) Direct controlling entity

Part II

Identification of Related Tax-Exempt Organizations Complete if the organization answered "Yes" on Form 990, Part IV, line 34 because it had one or more related tax-exempt organizations during the tax year.

(a) Name, address, and EIN of related organization	(b) Primary activity	(c) Legal domicile (state or foreign country)	(d) Exempt Code section	(e) Public charity status (if section 501(c)(3))	(f) Direct controlling entity	(g) Section 512(b)(13) controlled entity?
(a) Name, address, and EIN of related organization	(b) Primary activity	(c) Legal domicile (state or foreign country)	(d) Exempt Code section	(e) Public charity status (if section 501(c)(3))	(f) Direct controlling entity	Yes	No
(1)THE TRANSLATIONAL GENOMICS RESEARCH INST 445 N 5TH STREET SUITE 600 PHOENIX,AZ85004 75-3065445	RESEARCH	AZ	501(c)(3)	7	NA		No

For Paperwork Reduction Act Notice, see the Instructions for Form 990.

Cat. No. 50135Y

Schedule R (Form 990) 2015

Page 2

Part III

Identification of Related Organizations Taxable as a Partnership Complete if the organization answered "Yes" on Form 990, Part IV, line 34 because it had one or more related organizations treated as a partnership during the tax year.

(a) Name, address, and EIN of related organization	(b) Primary activity	(c) Legal domicile (state or foreign country)	(d) Direct controlling entity	(f) Share of total income	(g) Share of end-of-year assets	(h) Disproprtionate allocations?		(i) Code V-UBI amount in box 20 of Schedule K-1 (Form 1065)	(j) General or managing partner?
(a) Name, address, and EIN of related organization	(b) Primary activity	(c) Legal domicile (state or foreign country)	(d) Direct controlling entity	(f) Share of total income	(g) Share of end-of-year assets	Yes	No	(i) Code V-UBI amount in box 20 of Schedule K-1 (Form 1065)	Yes	No

Part IV

Identification of Related Organizations Taxable as a Corporation or Trust Complete if the organization answered "Yes" on Form 990, Part IV, line 34 because it had one or more related organizations treated as a corporation or trust during the tax year.

(a) Name, address, and EIN of related organization	(b) Primary activity	(c) Legal domicile (state or foreign country)	(d) Direct controlling entity	(e) Type of entity (C corp, S corp, or trust)	(f) Share of total income	(g) Share of end-of-year assets	(i) Section 512(b)(13) controlled entity?
(a) Name, address, and EIN of related organization	(b) Primary activity	(c) Legal domicile (state or foreign country)	(d) Direct controlling entity	(e) Type of entity (C corp, S corp, or trust)	(f) Share of total income	(g) Share of end-of-year assets	Yes	No

Schedule R (Form 990) 2015

Page 3

Part V

Transactions With Related Organizations Complete if the organization answered "Yes" on Form 990, Part IV, line 34, 35b, or 36.

Note. Complete line 1 if any entity is listed in Parts II, III, or IV of this schedule.

Yes

1 During the tax year, did the orgranization engage in any of the following transactions with one or more related organizations listed in Parts II-IV?

a Receipt of (i) interest, (ii) annuities, (iii) royalties, or (iv) rent from a controlled entity .....................

b Gift, grant, or capital contribution to related organization(s) ............................

Yes

c Gift, grant, or capital contribution from related organization(s) ............................

d Loans or loan guarantees to or for related organization(s) ............................

e Loans or loan guarantees by related organization(s) ............................

f Dividends from related organization(s) ............................

g Sale of assets to related organization(s) ............................

h Purchase of assets from related organization(s) ............................

i Exchange of assets with related organization(s) ............................

j Lease of facilities, equipment, or other assets to related organization(s) .......................

k Lease of facilities, equipment, or other assets from related organization(s) ......................

l Performance of services or membership or fundraising solicitations for related organization(s) .....................

Yes

m Performance of services or membership or fundraising solicitations by related organization(s) .................

n Sharing of facilities, equipment, mailing lists, or other assets with related organization(s) ...................

Yes

o Sharing of paid employees with related organization(s) ............................

Yes

p Reimbursement paid to related organization(s) for expenses ............................

q Reimbursement paid by related organization(s) for expenses ............................

Yes

r Other transfer of cash or property to related organization(s) ............................

s Other transfer of cash or property from related organization(s) ............................

If the answer to any of the above is "Yes," see the instructions for information on who must complete this line, including covered relationships and transaction thresholds.

(a) Name of related organization	(b) Transaction type (a-s)	(c) Amount involved	(d) Method of determining amount involved

Schedule R (Form 990) 2015

Page 4

Part VI

Unrelated Organizations Taxable as a Partnership Complete if the organization answered "Yes" on Form 990, Part IV, line 37.

Provide the following information for each entity taxed as a partnership through which the organization conducted more than five percent of its activities (measured by total assets or gross revenue) that was not a related organization. See instructions regarding exclusion for certain investment partnerships.

(a) Name, address, and EIN of entity	(b) Primary activity	(c) Legal domicile (state or foreign country)	(e) Are all partners section 501(c)(3) organizations?		(f) Share of total income	(g) Share of end-of-year assets	(h) Disproprtionate allocations?		(i) Code V-UBI amount in box 20 of Schedule K-1 (Form 1065)	(j) General or managing partner?
(a) Name, address, and EIN of entity	(b) Primary activity	(c) Legal domicile (state or foreign country)	Yes	No	(f) Share of total income	(g) Share of end-of-year assets	Yes	No	(i) Code V-UBI amount in box 20 of Schedule K-1 (Form 1065)	Yes	No

Schedule R (Form 990) 2015

Page 5

Part VII

Supplemental Information

Provide additional information for responses to questions on Schedule R (see instructions).

Return Reference	Explanation

Schedule R (Form 990) 2015

Additional Data

Software ID:
Software Version:

		Prior Year	Current Year
8	Contributions and grants (Part VIII, line 1h) .........	13,561,515	9,117,401
9	Program service revenue (Part VIII, line 2g) .........	0	0
10	Investment income (Part VIII, column (A), lines 3, 4, and 7d ) ....	1,004	1,005
11	Other revenue (Part VIII, column (A), lines 5, 6d, 8c, 9c, 10c, and 11e)	0	0
12	Total revenue—add lines 8 through 11 (must equal Part VIII, column (A), line 12)	13,562,519	9,118,406
13	Grants and similar amounts paid (Part IX, column (A), lines 1–3 )...	4,427,718	6,881,065
14	Benefits paid to or for members (Part IX, column (A), line 4).....	0	0
15	Salaries, other compensation, employee benefits (Part IX, column (A), lines 5–10)	937,442	780,788
16a	Professional fundraising fees (Part IX, column (A), line 11e) .....	0	0
b	Total fundraising expenses (Part IX, column (D), line 25) 1,178,368
17	Other expenses (Part IX, column (A), lines 11a–11d, 11f–24e)....	744,944	765,144
18	Total expenses. Add lines 13–17 (must equal Part IX, column (A), line 25)	6,110,104	8,426,997
19	Revenue less expenses. Subtract line 18 from line 12.......	7,452,415	691,409
		Beginning of Current Year	End of Year
20	Total assets (Part X, line 16).............	21,642,528	23,669,414
21	Total liabilities (Part X, line 26).............	4,943,600	6,279,170
22	Net assets or fund balances. Subtract line 21 from line 20.....	16,698,928	17,390,244

Sign Here

	Signature of officer	Date

	Type or print name and title


4a	(Code: ) (Expenses $ 6,881,065 including grants of $ 6,881,065 ) (Revenue $ 0 )
	SEE SCHEDULE O

4b	(Code: ) (Expenses $ including grants of $ ) (Revenue $ )












4c	(Code: ) (Expenses $ including grants of $ ) (Revenue $ )












4d	Other program services (Describe in Schedule O.)
	(Expenses $ including grants of $ ) (Revenue $ )
4e	Total program service expenses6,881,065

(A) Name and Title	(B) Average hours per week (list any hours for related organizations below dotted line)	(C) Position (do not check more than one box, unless person is both an officer and a director/trustee)			(D) Reportable compensation from the organization (W- 2/1099-MISC)	(E) Reportable compensation from related organizations (W- 2/1099-MISC)	(F) Estimated amount of other compensation from the organization and related organizations
(A) Name and Title
(18) Howard Young........................................................................ Board Member	1.0 .......................0.0	X			0	0	0
(19) Erin Massey........................................................................ Vice President	40.0 .......................0.0		X		0	133,294	8,958
(20) CHARLES K COLESON........................................................................ CHIEF FINANCIAL OFFICER	1.0 .......................29.0			X	0	157,822	1,974

1b	Sub-Total................
c	Total from continuation sheets to Part VII, Section A....
d	Total (add lines 1b and 1c)...........	0	2,323,095	308,189

1	Briefly describe the organization’s mission or most significant activities: BIOGENOMIC MEDICAL RESEARCH FUNDRAISING FOR THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (TGEN).
2	Check this box
3	Number of voting members of the governing body (Part VI, line 1a) ........	3	18
4	Number of independent voting members of the governing body (Part VI, line 1b) .....	4	15
5	Total number of individuals employed in calendar year 2015 (Part V, line 2a) ......	5	0
6	Total number of volunteers (estimate if necessary) .............	6	100
7a	Total unrelated business revenue from Part VIII, column (C), line 12 ........	7a	0
b	Net unrelated business taxable income from Form 990-T, line 34 .........	7b	0

(A) Name and business address	(B) Description of services	(C) Compensation
TRANSLATIONAL GENOMICS RESEARCH INS, 445 N 5th Street Suite 600 Phoenix,AZ85004	MANAGEMENT SERVICES	108,000




2 Total number of independent contractors (including but not limited to those listed above) who received more than $100,000 of compensation from the organization 1

1a	Federated campaigns..		1a
b	Membership dues..		1b
c	Fundraising events..		1c	0
d	Related organizations		1d
e	Government grants (contributions)		1e

f	All other contributions, gifts, grants, and similar amounts not included above		1f	9,117,401

g	Noncash contributions included in lines 1a-1f:$ 0
h Total.Add lines 1a-1f.......		9,117,401

		Business Code
2a
b
c
d
e
f	All other program service revenue.
g Total.Add lines 2a–2f.....		0

3 Investment income (including dividends, interest, and othersimilar amounts) ..........			1,005		1,005
4 Income from investment of tax-exempt bond proceeds			0
5 Royalties...........			0
		(ii) Personal	(i) Real
6a	Gross rents
b	Less: rental expenses
c	Rental income or (loss)	0	0
d	Net rental income or (loss)......			0
		(ii) Other	(i) Securities
7a	Gross amount from sales of assets other than inventory
b	Less: cost or other basis and sales expenses
c	Gain or (loss)
d	Net gain or (loss).....			0
8a	Gross income from fundraising events (not including $ of contributions reported on line 1c). See Part IV, line 18 ....
	a
b	Less: direct expenses ...b
c	Net income or (loss) from fundraising events..			0
9a	Gross income from gaming activities. See Part IV, line 19 ...
	a
b	Less: direct expenses ...b
c	Net income or (loss) from gaming activities..			0
10a	Gross sales of inventory, less returns and allowances ..
	a
b	Less: cost of goods sold ..b
c	Net income or (loss) from sales of inventory..			0
Business Code			Miscellaneous Revenue
11a
b
c
d	All other revenue ....
e	Total. Add lines 11a–11d ......			0
12	Total revenue. See Instructions......			9,118,406	0	1,005

1	Grants and other assistance to domestic organizations and domestic governments. See Part IV, line 21	6,881,065	6,881,065
2	Grants and other assistance to individuals in the United States. See Part IV, line 22	0	0
3	Grants and other assistance to governments, organizations, and individuals outside the United States. See Part IV, lines 15 and 16	0	0
4	Benefits paid to or for members	0	0
5	Compensation of current officers, directors, trustees, and key employees ....	505,109	0	50,511	454,598
6	Compensation not included above, to disqualified persons (as defined under section 4958(f)(1)) and persons described in section 4958(c)(3)(B) ....	0	0	0	0
7	Other salaries and wages	275,679	0	89,548	186,131
8	Pension plan accruals and contributions (include section 401(k) and 403(b) employer contributions) ....	0	0	0	0
9	Other employee benefits .......	0	0	0	0
10	Payroll taxes ...........	0	0	0	0
11	Fees for services (non-employees):
a	Management ......	0	0	0	0
b	Legal .........	104	0	104	0
c	Accounting ...........	0	0	0	0
d	Lobbying ...........	0	0	0	0
e	Professional fundraising services. See Part IV, line 17	0			0
f	Investment management fees ......	0	0	0	0
g	Other (If line 11g amount exceeds 10% of line 25, column (A) amount, list line 11g expenses on Schedule O)	130,640		130,640
12	Advertising and promotion ....	143,634	0	14,363	129,271
13	Office expenses .......	189,510	0	18,951	170,559
14	Information technology ......	0	0	0	0
15	Royalties ..	0	0	0	0
16	Occupancy ...........	71,632	0	7,163	64,469
17	Travel ............	34,822	0	3,482	31,340
18	Payments of travel or entertainment expenses for any federal, state, or local public officials .	0	0	0	0
19	Conferences, conventions, and meetings ....	157,778	0	15,778	142,000
20	Interest ...........	0	0	0	0
21	Payments to affiliates .......	0	0	0	0
22	Depreciation, depletion, and amortization ..	0	0	0	0
23	Insurance ...	0	0	0	0
24	Other expenses. Itemize expenses not covered above (List miscellaneous expenses in line 24e. If line 24e amount exceeds 10% of line 25, column (A) amount, list line 24e expenses on Schedule O.)
a	DUES & SUBSCRIPTIONS	36,691	0	36,691	0
b	ALL OTHER EXPENSES	333	0	333	0
c
d
e	All other expenses
25	Total functional expenses. Add lines 1 through 24e	8,426,997	6,881,065	367,564	1,178,368
26	Joint costs. Complete this line only if the organization reported in column (B) joint costs from a combined educational campaign and fundraising solicitation. Check here if following SOP 98-2 (ASC 958-720).	0

1	Cash–non-interest-bearing ........			36,922	1	163,967
2	Savings and temporary cash investments .........			10,722,866	2	13,528,527
3	Pledges and grants receivable, net ......			10,871,204	3	9,965,268
4	Accounts receivable, net .............			0	4	0
5	Loans and other receivables from current and former officers, directors, trustees, key employees, and highest compensated employees. Complete Part II of Schedule L
				0	5	0
6	Loans and other receivables from other disqualified persons (as defined under section 4958(f)(1)), persons described in section 4958(c)(3)(B), and contributing employers and sponsoring organizations of section 501(c)(9) voluntary employees' beneficiary organizations (see instructions) Complete Part II of Schedule L
				0	6	0
7	Notes and loans receivable, net ....			0	7	0
8	Inventories for sale or use ........			5,049	8	5,165
9	Prepaid expenses and deferred charges ......			6,487	9	6,487
10a	Land, buildings, and equipment: cost or other basis. Complete Part VI of Schedule D	10a	0
b	Less: accumulated depreciation	10b	0		10c
11	Investments—publicly traded securities .			0	11	0
12	Investments—other securities. See Part IV, line 11 .....			0	12	0
13	Investments—program-related. See Part IV, line 11 ..			0	13	0
14	Intangible assets ...............			0	14	0
15	Other assets. See Part IV, line 11 ...........			0	15	0
16	Total assets. Add lines 1 through 15 (must equal line 34)...			21,642,528	16	23,669,414

17	Accounts payable and accrued expenses .....	4,943,600	17	6,279,170
18	Grants payable ...	0	18	0
19	Deferred revenue .........	0	19	0
20	Tax-exempt bond liabilities .........	0	20	0
21	Escrow or custodial account liability. Complete Part IV of Schedule D	0	21	0
22	Loans and other payables to current and former officers, directors, trustees, key employees, highest compensated employees, and disqualified
	persons. Complete Part II of Schedule L..	0	22	0
23	Secured mortgages and notes payable to unrelated third parties ..	0	23	0
24	Unsecured notes and loans payable to unrelated third parties ..	0	24	0
25	Other liabilities (including federal income tax, payables to related third parties, and other liabilities not included on lines 17-24). Complete Part X of Schedule D	0	25	0
26	Total liabilities. Add lines 17 through 25..	4,943,600	26	6,279,170

	Organizations that follow SFAS 117 (ASC 958), check here and complete lines 27 through 29, and lines 33 and 34.
27	Unrestricted net assets	-3,589,898	27	-4,439,389
28	Temporarily restricted net assets ...........	20,226,733	28	21,767,540
29	Permanently restricted net assets	62,093	29	62,093
	Organizations that do not follow SFAS 117 (ASC 958), check here and complete lines 30 through 34.
30	Capital stock or trust principal, or current funds .....		30
31	Paid-in or capital surplus, or land, building or equipment fund ...		31
32	Retained earnings, endowment, accumulated income, or other funds		32
33	Total net assets or fund balances ...........	16,698,928	33	17,390,244
34	Total liabilities and net assets/fund balances ........	21,642,528	34	23,669,414