Form990


Department of the TreasuryInternal Revenue Service
Return of Organization Exempt From Income Tax
Under section 501(c), 527, or 4947(a)(1) of the Internal Revenue Code (except private foundations)
MediumBullet Do not enter social security numbers on this form as it may be made public.
MediumBullet Go to www.irs.gov/Form990 for instructions and the latest information.
OMB No. 1545-0047
2021
Open to Public Inspection
A For the 2021 calendar year, or tax year beginning 09-01-2021 , and ending 08-31-2022
BCheck if applicable:
CName of organization
Howard Hughes Medical Institute
 
 
Doing business as
 
 
Number and street (or P.O. box if mail is not delivered to street address)
4000 JONES BRIDGE ROAD
 
Room/suite
City or town, state or province, country, and ZIP or foreign postal code
CHEVY CHASE, MD208156789
D Employer identification number

59-0735717
E Telephone number

G Gross receipts $ 24,774,355,258
F Name and address of principal officer:
Erin O'Shea
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD208156789
I
Tax-exempt status: (   ) LeftBullet (insert no.) or
J
Website:MediumBullet
WWW.HHMI.ORG
H(a)
Is this a group return for
subordinates?
H(b)
Are all subordinates
included?
If "No," attach a list. See instructions.
H(c)
Group exemption number MediumBullet  
K Form of organization:  
L Year of formation: 1953
M State of legal domicile: DE
Part I
Summary
Activities  & Governance 1 Briefly describe the organization’s mission or most significant activities: THE HOWARD HUGHES MEDICAL INSTITUTE IS A PHILANTHROPY THAT SERVES SOCIETY THROUGH THE DIRECT CONDUCT OF BIOMEDICAL RESEARCH AND SUPPORT FOR PROGRAMS IN SCIENCE EDUCATION.
2 Check this box MediumBullet
3 Number of voting members of the governing body (Part VI, line 1a) ........ 3 11
4 Number of independent voting members of the governing body (Part VI, line 1b) ..... 4 11
5 Total number of individuals employed in calendar year 2021 (Part V, line 2a) ...... 5 2,327
6 Total number of volunteers (estimate if necessary) ............. 6 0
7a Total unrelated business revenue from Part VIII, column (C), line 12 ........ 7a 78,935,443
b Net unrelated business taxable income from Form 990-T, Part I, line 11 ......... 7b 0
Revenues Prior Year Current Year
8 Contributions and grants (Part VIII, line 1h) ......... 2,210,362 2,025,577
9 Program service revenue (Part VIII, line 2g) ......... 2,223,724 3,865,374
10 Investment income (Part VIII, column (A), lines 3, 4, and 7d ) .... 2,072,096,518 2,087,454,899
11 Other revenue (Part VIII, column (A), lines 5, 6d, 8c, 9c, 10c, and 11e) 20,263,474 24,131,707
12 Total revenue—add lines 8 through 11 (must equal Part VIII, column (A), line 12) 2,096,794,078 2,117,477,557
Expenses; 13 Grants and similar amounts paid (Part IX, column (A), lines 1–3 )... 36,219,347 30,168,536
14 Benefits paid to or for members (Part IX, column (A), line 4).....   0
15 Salaries, other compensation, employee benefits (Part IX, column (A), lines 5–10) 381,757,458 398,296,704
16a Professional fundraising fees (Part IX, column (A), line 11e) .....   0
b Total fundraising expenses (Part IX, column (D), line 25) MediumBullet0    
17 Other expenses (Part IX, column (A), lines 11a–11d, 11f–24e).... 536,787,278 557,824,715
18 Total expenses. Add lines 13–17 (must equal Part IX, column (A), line 25) 954,764,083 986,289,955
19 Revenue less expenses. Subtract line 18 from line 12....... 1,142,029,995 1,131,187,602
Net Assets or Fund Balances; Beginning of Current Year End of Year
20 Total assets (Part X, line 16)............. 29,343,107,763 25,877,392,654
21 Total liabilities (Part X, line 26)............. 2,244,173,151 1,837,723,670
22 Net assets or fund balances. Subtract line 21 from line 20..... 27,098,934,612 24,039,668,984
Part II
Signature Block
Under penalties of perjury, I declare that I have examined this return, including accompanying schedules and statements, and to the best of my knowledge and belief, it is true, correct, and complete. Declaration of preparer (other than officer) is based on all information of which preparer has any knowledge.
Sign Here
JumboBullet
Signature of officer Date
JumboBullet
Type or print name and title
Paid Preparer Use Only
Print/Type preparer's name
Preparer's signature
Date
PTIN
Firm's name MediumBullet

Firm's EIN MediumBullet
Firm's address MediumBullet



Phone no.
May the IRS discuss this return with the preparer shown above? (see instructions) ..........
For Paperwork Reduction Act Notice, see the separate instructions.
Cat. No. 11282Y Form 990 (2021)
Form 990 (2021)
Page 2
Part III
Statement of Program Service Accomplishments
Check if Schedule O contains a response or note to any line in this Part III..............
1
Briefly describe the organization’s mission: THE HOWARD HUGHES MEDICAL INSTITUTE (INSTITUTE OR HHMI) IS THE NATION'S LARGEST PRIVATE BIOMEDICAL RESEARCH INSTITUTION, WITH OVER $24 BILLION IN NET ASSETS AT THE END OF ITS 2022 FISCAL YEAR. THE MISSION OF THE INSTITUTE HAS REMAINED CONSTANT SINCE ITS FOUNDING IN 1953. AS ITS RESTATED ARTICLES OF INCORPORATION STATE THE PRIMARY PURPOSE AND OBJECTIVE OF THE HOWARD HUGHES MEDICAL INSTITUTE SHALL BE THE PROMOTION OF HUMAN KNOWLEDGE BY CONDUCTING DISCOVERY RESEARCH AND SCIENCE EDUCATION, PRINCIPALLY WITHIN FIELDS ASSOCIATED WITH BASIC BIOMEDICAL SCIENCES, AND THE DISSEMINATION AND APPLICATION OF THAT KNOWLEDGE FOR THE BENEFIT OF HUMANITY.
2
Did the organization undertake any significant program services during the year which were not listed on
the prior Form 990 or 990-EZ? .....................
If "Yes," describe these new services on Schedule O.
3
Did the organization cease conducting, or make significant changes in how it conducts, any program
services? ...........................
If "Yes," describe these changes on Schedule O.
4
Describe the organization’s program service accomplishments for each of its three largest program services, as measured by expenses. Section 501(c)(3) and 501(c)(4) organizations are required to report the amount of grants and allocations to others, the total expenses, and revenue, if any, for each program service reported.
4a (Code:   ) (Expenses $ 680,574,856 including grants of $ 0 ) (Revenue $ 2,702,904 )
MEDICAL RESEARCH ORGANIZATION ACTIVITIES (A) THE HHMI INVESTIGATOR PROGRAM (B) JANELIA RESEARCH CAMPUS (A) The HHMI Investigator Program The Howard Hughes Medical Institute's approach to biomedical research can be summarized in three words: people, not projects. By employing scientists as HHMI Investigators - rather than awarding research grants - the Institute provides long-term, flexible funding that enables its researchers to pursue their scientific interests wherever they lead. HHMI believes that scientists of exceptional talent and imagination will make fundamental discoveries of lasting scientific value and benefit to humanity if they are given the resources, time, and freedom to pursue challenging questions. HHMI Investigators receive a seven-year appointment, which is renewable pending favorable scientific review. The Institute nurtures the creativity and intellectual daring of scientists who are willing to set aside conventional wisdom or the easy question for a fundamental problem that may take many years to solve. Among the characteristics that distinguish this group of scientists are qualities such as creativity, a penchant for risk-taking, and a commitment to discovery, productivity, and perseverance. This unique research model is an imaginative and powerful alternative to funding biomedical research through grants. The HHMI Investigator Program employs more than 260 HHMI researchers, among them 15 Nobel laureates and more than 150 members of the National Academy of Sciences. HHMI Investigators direct Institute research laboratories on the campuses of about 60 universities and other research organizations throughout the United States. Since the early 1990s, Investigators have been selected through rigorous national competitions. The Institute solicits applications directly from scientists at medical schools and other research institutions in the United States, with the aim of identifying those who have the potential to make significant contributions to science. HHMI employs an open application process to ensure that it is selecting its researchers from a broad and deep pool of scientific talent. In February 2022, Leslie B. Vosshall, PhD, became HHMI's Vice President and Chief Scientific Officer. Vosshall, who has been an HHMI Investigator at The Rockefeller University since 2008, leads and manages HHMI's Science department portfolio, which includes the HHMI Investigator, Hanna H. Gray Fellows, and Freeman Hrabowski Scholars programs, among other efforts. (B) Janelia Research Campus HHMI's Janelia Research Campus in Ashburn, Virginia, helps open scientific fields by breaking through technical and intellectual barriers. At Janelia, integrated teams of lab scientists and tool-builders pursue a small number of scientific questions with potential for transformative impact. To drive science forward, methods, results, and tools are shared with the scientific community. In September 2022, Janelia began a recruitment campaign to hire group leaders and senior group leaders to lead laboratories across research areas, particularly the newest research area, 4D Cellular Physiology (4DCP). 4DCP aims to examine how cells work and communicate across scales to build and maintain organs and organisms, an effort that leverages Janelia's strengths in developing cutting-edge molecular tools and imaging technologies as well as computational and theoretical methods. As a result of the recruitment effort, Janelia will add two senior group leaders and five group leaders in 4DCP, one senior group leader in Molecular Tools and Imaging, one group leader in Computation & Theory, and one group leader in Mechanistic Cognitive Neuroscience. These scientists will join Janelia in early FY23. In the current fiscal year, there were 24 group leaders, 12 senior group leaders, three fellows, and six Janelia scholars at Janelia, in addition to graduate students, other scientific trainees, and visiting scientists. In 2022, Janelia also restarted its vibrant scientific conference program, which brings many scientists to its campus each year for educational meetings.
4b (Code:   ) (Expenses $ 71,457,661 including grants of $ 29,591,916 ) (Revenue $ 1,162,470 )
SCIENCE EDUCATION AND RESEARCH GRANT PROGRAMS (A) SCIENCE EDUCATION GRANT AND RESEARCH PROGRAMS (B) EDUCATIONAL MEDIA GROUP (C) TANGLED BANK STUDIOS (D) HANNA H GRAY FELLOWS (E) E-LIFE OPEN ACCESS JOURNAL (CONTINUED ON SCHEDULE O)
4c (Code:   ) (Expenses $ 571,733 including grants of $ 576,620 ) (Revenue $ 0 )
SUPPORT FOR INTERNATIONAL SCIENCE 4c: Support for International Science International Research Scholars Program HHMI continues to support forty-one scientists from 16 countries who were selected in 2017 as International Research Scholars, exceptional early-career scientists poised to advance biomedical research across the globe. HHMI teamed up with the Bill & Melinda Gates Foundation, Wellcome, and the Calouste Gulbenkian Foundation to develop scientific talent around the world, and with these partners awarded a total of over $29.3 million to this group of scholars. Each researcher receives a five-year award of $715,000, including indirect costs. The award is a major boost for scientists early in their careers and offers the freedom to pursue new research directions and creative projects that could develop into top-notch scientific programs. Africa Health Research Institute in South Africa In 2009, HHMI helped launch the KwaZulu-Natal Research Institute for TB-HIV (K-RITH) in collaboration with the University of KwaZulu-Natal (UKZN) and has provided significant funding to support its research efforts. In 2016, in a move to improve the health of people locally and globally, K-RITH joined forces with the Africa Centre for Population Health to form a groundbreaking new interdisciplinary institute to fight tuberculosis (TB), HIV and related diseases. The new organization, the Africa Health Research Institute (AHRI), is located at the heart of South Africa's TB and HIV co-epidemic in KwaZulu-Natal Province. The effort brings together the Africa Centre's detailed population data from over 100,000 participants, with K-RITH's expertise in basic science and its world-class laboratory facilities. HHMI, together with Wellcome, continues to provide grant support to AHRI, with the University College London and UKZN serving as significant academic partners. AHRI is committed to working towards the elimination of HIV and TB. To achieve this, the institute brings together leading researchers from different fields, uses cutting-edge science to improve people's health, and helps to train the next generation of African scientists.
4d Other program services (Describe in Schedule O.)
(Expenses $   including grants of $   ) (Revenue $   )
4e Total program service expensesMediumBullet752,604,250
Form 990 (2021)
Form 990 (2021)
Page 3
Part IV
Checklist of Required Schedules
Yes
No
1
Is the organization described in section 501(c)(3) or 4947(a)(1) (other than a private foundation)? If "Yes," complete Schedule AClick to see attachment.....................
1
Yes
 
2
Is the organization required to complete Schedule B, Schedule of Contributors? See instructions. Click to see attachment...
2
Yes
 
3
Did the organization engage in direct or indirect political campaign activities on behalf of or in opposition to candidates for public office? If "Yes," complete Schedule C, Part I.............
3
 
No
4
Section 501(c)(3) organizations. Did the organization engage in lobbying activities, or have a section 501(h) election in effect during the tax year? If "Yes," complete Schedule C, Part IIClick to see attachment.........
4
Yes
 
5
Is the organization a section 501(c)(4), 501(c)(5), or 501(c)(6) organization that receives membership dues, assessments, or similar amounts as defined in Rev. Proc. 98-19? If "Yes," complete Schedule C, Part III..
5
 
 
6
Did the organization maintain any donor advised funds or any similar funds or accounts for which donors have the right to provide advice on the distribution or investment of amounts in such funds or accounts? If "Yes," complete Schedule D, Part I.........................
6
 
No
7
Did the organization receive or hold a conservation easement, including easements to preserve open space,
the environment, historic land areas, or historic structures? If "Yes," complete Schedule D, Part II....
7
 
No
8
Did the organization maintain collections of works of art, historical treasures, or other similar assets? If "Yes,"
complete Schedule D,
Part III..............
8
 
No
9
Did the organization report an amount in Part X, line 21 for escrow or custodial account liability; serve as a custodian for amounts not listed in Part X; or provide credit counseling, debt management, credit repair, or debt negotiation services? If "Yes," complete Schedule D, Part IV..............
9
 
No
10
Did the organization, directly or through a related organization, hold assets in temporarily restricted endowments, permanent endowments, or quasi endowments? If "Yes," complete Schedule D, Part V......
10
 
No
11
If the organization’s answer to any of the following questions is "Yes," then complete Schedule D, Parts VI, VII, VIII, IX, or X, as applicable.
a
Did the organization report an amount for land, buildings, and equipment in Part X, line 10? If "Yes," complete
Schedule D,
Part VI. Click to see attachment...................
11a
Yes
 
b
Did the organization report an amount for investments—other securities in Part X, line 12 that is 5% or more of its total assets reported in Part X, line 16? If "Yes," complete Schedule D, Part VIIClick to see attachment.......
11b
Yes
 
c
Did the organization report an amount for investments—program related in Part X, line 13 that is 5% or more of its total assets reported in Part X, line 16? If "Yes," complete Schedule D, Part VIII.......
11c
 
No
d
Did the organization report an amount for other assets in Part X, line 15 that is 5% or more of its total assets reported in Part X, line 16? If "Yes," complete Schedule D, Part IX............
11d
 
No
e
Did the organization report an amount for other liabilities in Part X, line 25? If "Yes," complete Schedule D, Part XClick to see attachment
11e
Yes
 
f
Did the organization’s separate or consolidated financial statements for the tax year include a footnote that addresses the organization’s liability for uncertain tax positions under FIN 48 (ASC 740)? If "Yes," complete Schedule D, Part XClick to see attachment
11f
Yes
 
12a
Did the organization obtain separate, independent audited financial statements for the tax year? If "Yes," complete
Schedule D, Parts XI and XII
......................
12a
 
No
b
Was the organization included in consolidated, independent audited financial statements for the tax year? If "Yes," and if the organization answered "No" to line 12a, then completing Schedule D, Parts XI and XII is optional Click to see attachment
12b
Yes
 
13
Is the organization a school described in section 170(b)(1)(A)(ii)? If "Yes," complete Schedule E
13
 
No
14a
Did the organization maintain an office, employees, or agents outside of the United States? .....
14a
 
No
b
Did the organization have aggregate revenues or expenses of more than $10,000 from grantmaking, fundraising, business, investment, and program service activities outside the United States, or aggregate foreign investments valued at $100,000 or more? If "Yes," complete Schedule F, Parts I and IV.........Click to see attachment
14b
Yes
 
15
Did the organization report on Part IX, column (A), line 3, more than $5,000 of grants or other assistance to or for any foreign organization? If “Yes,” complete Schedule F, Parts II and IV.....Click to see attachment
15
Yes
 
16
Did the organization report on Part IX, column (A), line 3, more than $5,000 of aggregate grants or other assistance to or for foreign individuals? If “Yes,” complete Schedule F, Parts III and IV...
16
 
No
17
Did the organization report a total of more than $15,000 of expenses for professional fundraising services on Part IX, column (A), lines 6 and 11e? If "Yes," complete Schedule G, Part I. See instructions. ....
17
 
No
18
Did the organization report more than $15,000 total of fundraising event gross income and contributions on Part VIII, lines 1c and 8a? If "Yes," complete Schedule G, Part II............
18
 
No
19
Did the organization report more than $15,000 of gross income from gaming activities on Part VIII, line 9a? If "Yes," complete Schedule G, Part III...................
19
 
No
20a
Did the organization operate one or more hospital facilities? If "Yes," complete Schedule H....
20a
 
No
b
If "Yes" to line 20a, did the organization attach a copy of its audited financial statements to this return?
20b
 
 
21
Did the organization report more than $5,000 of grants or other assistance to any domestic organization or domestic government on Part IX, column (A), line 1? If “Yes,” complete Schedule I, Parts I and II.....Click to see attachment
21
Yes
 
Form 990 (2021)
Form 990 (2021)
Page 4
Part IV
Checklist of Required Schedules (continued)
Yes
No
22
Did the organization report more than $5,000 of grants or other assistance to or for domestic individuals on Part IX, column (A), line 2? If “Yes,” complete Schedule I, Parts I and III........Click to see attachment
22
Yes
 
23
Did the organization answer "Yes" to Part VII, Section A, line 3, 4, or 5, about compensation of the organization’s current and former officers, directors, trustees, key employees, and highest compensated employees? If "Yes," complete Schedule J....................... Click to see attachment
23
Yes
 
24a
Did the organization have a tax-exempt bond issue with an outstanding principal amount of more than $100,000 as of the last day of the year, that was issued after December 31, 2002? If “Yes,” answer lines 24b through 24d and complete Schedule K. If “No,” go to line 25a...............Click to see list of attachments
24a
Yes
 
b
Did the organization invest any proceeds of tax-exempt bonds beyond a temporary period exception?...
24b
 
No
c
Did the organization maintain an escrow account other than a refunding escrow at any time during the year
to defease any tax-exempt bonds? ...............
24c
 
No
d
Did the organization act as an "on behalf of" issuer for bonds outstanding at any time during the year?...
24d
 
No
25a
Section 501(c)(3), 501(c)(4), and 501(c)(29) organizations. Did the organization engage in an excess benefit transaction with a disqualified person during the year? If "Yes," complete Schedule L, Part I ....
25a
 
No
b
Is the organization aware that it engaged in an excess benefit transaction with a disqualified person in a prior year, and that the transaction has not been reported on any of the organization’s prior Forms 990 or 990-EZ? If "Yes," complete Schedule L, Part I.......................
25b
 
No
26
Did the organization report any amount on Part X, line 5 or 22 for receivables from or payables to any current or former officer, director, trustee, key employee, creator or founder, substantial contributor, or 35% controlled entity or family member of any of these persons? If "Yes," complete Schedule L, Part II...........
26
 
No
27
Did the organization provide a grant or other assistance to any current or former officer, director, trustee, key employee, creator or founder, substantial contributor, or employee thereof, a grant selection committee member, or to a 35% controlled entity (including an employee thereof) or family member of any of these persons?
If "Yes," complete
Schedule L, Part III.........................
27
 
No
28
Was the organization a party to a business transaction with one of the following parties (see the Schedule L, Part IV instructions for applicable filing thresholds, conditions, and exceptions):
a
A current or former officer, director, trustee, key employee, creator or founder, or substantial contributor? If "Yes," complete Schedule L, Part IV......................
28a
 
No
b
A family member of any individual described in line 28a? If "Yes," complete Schedule L, Part IV.....Click to see attachment
28b
Yes
 
c
A 35% controlled entity of one or more individuals and/or organizations described in line 28a or 28b? If "Yes," complete Schedule L, Part IV.....................
28c
 
No
29
Did the organization receive more than $25,000 in non-cash contributions? If "Yes," complete Schedule M..
29
 
No
30
Did the organization receive contributions of art, historical treasures, or other similar assets, or qualified conservation contributions? If "Yes," complete Schedule M .................
30
 
No
31
Did the organization liquidate, terminate, or dissolve and cease operations? If "Yes," complete Schedule N, Part I
31
 
No
32
Did the organization sell, exchange, dispose of, or transfer more than 25% of its net assets? If "Yes," complete Schedule N, Part II........................
32
 
No
33
Did the organization own 100% of an entity disregarded as separate from the organization under Regulations sections 301.7701-2 and 301.7701-3? If "Yes," complete Schedule R, Part I............Click to see attachment
33
Yes
 
34
Was the organization related to any tax-exempt or taxable entity? If "Yes," complete Schedule R, Part II, III, or IV, and Part V, line 1.........................Click to see attachment
34
Yes
 
35a
Did the organization have a controlled entity within the meaning of section 512(b)(13)?
35a
Yes
 
b
If ‘Yes’ to line 35a, did the organization receive any payment from or engage in any transaction with a controlled entity within the meaning of section 512(b)(13)? If "Yes," complete Schedule R, Part V, line 2 ...Click to see attachment
35b
Yes
 
36
Section 501(c)(3) organizations. Did the organization make any transfers to an exempt non-charitable related organization? If "Yes," complete Schedule R, Part V, line 2.............
36
 
No
37
Did the organization conduct more than 5% of its activities through an entity that is not a related organization and that is treated as a partnership for federal income tax purposes? If "Yes," complete Schedule R, Part VI
37
 
No
38
Did the organization complete Schedule O and provide explanations on Schedule O for Part VI, lines 11b and 19? Note. All Form 990 filers are required to complete Schedule O. ............
38
Yes
 
Part V
Statements Regarding Other IRS Filings and Tax Compliance
Check if Schedule O contains a response or note to any line in this Part V...........
Yes
No
1a
Enter the number reported in box 3 of Form 1096. Enter -0- if not applicable ..
1a
551
b
Enter the number of Forms W-2G included on line 1a. Enter -0- if not applicable .
1b
0
c
Did the organization comply with backup withholding rules for reportable payments to vendors and reportable gaming (gambling) winnings to prize winners? ..................
1c
Yes
 
Form 990 (2021)
Form 990 (2021)
Page 5
Part V
Statements Regarding Other IRS Filings and Tax Compliance (continued)
2a
Enter the number of employees reported on Form W-3, Transmittal of Wage and
Tax Statements, filed for the calendar year ending with or within the year covered by this return ..................
2a
2,327
b
If at least one is reported on line 2a, did the organization file all required federal employment tax returns?
Note. If the sum of lines 1a and 2a is greater than 250, you may be required to e-file. See instructions.
2b
Yes
 
3a
Did the organization have unrelated business gross income of $1,000 or more during the year?...
3a
Yes
 
b
If “Yes,” has it filed a Form 990-T for this year? If “No” to line 3b, provide an explanation in Schedule O...
3b
Yes
 
4a
At any time during the calendar year, did the organization have an interest in, or a signature or other authority over, a financial account in a foreign country (such as a bank account, securities account, or other financial account)? ..
4a
Yes
 
b
If "Yes," enter the name of the foreign country: MediumBulletHK , IN , ID , EI , IT , JA , JE , JO , KS , LU , MT , IM , AS , MP , MX , MN , NL , RP , RS , SN , SF , SP , SW , SZ , TW , TH , TU , BE , AE , UK , BD , BR , VI , CA , CJ , CI , AN , DA , FI , FR , GM , GK
See instructions for filing requirements for FinCEN Form 114, Report of Foreign Bank and Financial Accounts (FBAR).
5a
Was the organization a party to a prohibited tax shelter transaction at any time during the tax year? ..
5a
 
No
b
Did any taxable party notify the organization that it was or is a party to a prohibited tax shelter transaction?
5b
 
No
c
If "Yes," to line 5a or 5b, did the organization file Form 8886-T? ............
5c
 
 
6a
Does the organization have annual gross receipts that are normally greater than $100,000, and did the organization solicit any contributions that were not tax deductible as charitable contributions? ...
6a
 
No
b
If "Yes," did the organization include with every solicitation an express statement that such contributions or gifts were not tax deductible? ......................
6b
 
 
7
Organizations that may receive deductible contributions under section 170(c).
a
Did the organization receive a payment in excess of $75 made partly as a contribution and partly for goods and services provided to the payor? ....................
7a
 
No
b
If "Yes," did the organization notify the donor of the value of the goods or services provided? .....
7b
 
 
c
Did the organization sell, exchange, or otherwise dispose of tangible personal property for which it was required to file Form 8282? .........................
7c
 
No
d
If "Yes," indicate the number of Forms 8282 filed during the year ....
7d
 
e
Did the organization receive any funds, directly or indirectly, to pay premiums on a personal benefit contract?
7e
 
No
f
Did the organization, during the year, pay premiums, directly or indirectly, on a personal benefit contract? ..
7f
 
No
g
If the organization received a contribution of qualified intellectual property, did the organization file Form 8899 as required? ......................
7g
 
 
h
If the organization received a contribution of cars, boats, airplanes, or other vehicles, did the organization file a Form 1098-C? ..........................
7h
 
 
8
Sponsoring organizations maintaining donor advised funds. Did a donor advised fund maintained by the sponsoring organization have excess business holdings at any time during the year? ........
8
 
 
9
Sponsoring organizations maintaining donor advised funds.
a
Did the sponsoring organization make any taxable distributions under section 4966?........
9a
 
 
b
Did the sponsoring organization make a distribution to a donor, donor advisor, or related person?...
9b
 
 
10
Section 501(c)(7) organizations. Enter:
a
Initiation fees and capital contributions included on Part VIII, line 12 ...
10a
 
b
Gross receipts, included on Form 990, Part VIII, line 12, for public use of club facilities
10b
 
11
Section 501(c)(12) organizations. Enter:
a
Gross income from members or shareholders .........
11a
 
b
Gross income from other sources. (Do not net amounts due or paid to other sources against amounts due or received from them.) ..........
11b
 
12a
Section 4947(a)(1) non-exempt charitable trusts. Is the organization filing Form 990 in lieu of Form 1041?
12a
 
 
b
If "Yes," enter the amount of tax-exempt interest received or accrued during the year.
12b
 
13
Section 501(c)(29) qualified nonprofit health insurance issuers.
a
Is the organization licensed to issue qualified health plans in more than one state? .........
Note. See the instructions for additional information the organization must report on Schedule O.
13a
 
 
b
Enter the amount of reserves the organization is required to maintain by the states in which the organization is licensed to issue qualified health plans ....
13b
 
c
Enter the amount of reserves on hand ............
13c
 
14a
Did the organization receive any payments for indoor tanning services during the tax year?.....
14a
 
No
b
If "Yes," has it filed a Form 720 to report these payments? If "No," provide an explanation in Schedule O..
14b
 
 
15
Is the organization subject to the section 4960 tax on payment(s) of more than $1,000,000 in remuneration or excess parachute payment(s) during the year? ....................
If "Yes," see the instructions and file Form 4720, Schedule N.
15
Yes
 
16
Is the organization an educational institution subject to the section 4968 excise tax on net investment income? ..
If "Yes," complete Form 4720, Schedule O.
16
 
No
17
Section 501(c)(21) organizations. Did the trust, any disqualified person, or mine operator engage in any activities that would result in the imposition of an excise tax under section 4951, 4952, or 4953? ..
If "Yes," complete Form 6069.
17
 
 
Form 990 (2021)
Form 990 (2021)
Page 6
Part VI
Governance, Management, and Disclosure. For each "Yes" response to lines 2 through 7b below, and for a "No" response to lines 8a, 8b, or 10b below, describe the circumstances, processes, or changes in Schedule O. See instructions.
Check if Schedule O contains a response or note to any line in this Part VI..............
Section A. Governing Body and Management
Yes
No
1a
Enter the number of voting members of the governing body at the end of the tax year
1a
11
If there are material differences in voting rights among members of the governing body, or if the governing body delegated broad authority to an executive committee or similar committee, explain in Schedule O.
b
Enter the number of voting members included in line 1a, above, who are independent
1b
11
2
Did any officer, director, trustee, or key employee have a family relationship or a business relationship with any other officer, director, trustee, or key employee? .................
2
 
No
3
Did the organization delegate control over management duties customarily performed by or under the direct supervision of officers, directors or trustees, or key employees to a management company or other person? .
3
 
No
4
Did the organization make any significant changes to its governing documents since the prior Form 990 was filed? .
4
 
No
5
Did the organization become aware during the year of a significant diversion of the organization’s assets? .
5
 
No
6
Did the organization have members or stockholders? ................
6
 
No
7a
Did the organization have members, stockholders, or other persons who had the power to elect or appoint one or more members of the governing body? ....................
7a
 
No
b
Are any governance decisions of the organization reserved to (or subject to approval by) members, stockholders, or persons other than the governing body? ...................
7b
 
No
8
Did the organization contemporaneously document the meetings held or written actions undertaken during the year by the following:
a
The governing body? .......................
8a
Yes
 
b
Each committee with authority to act on behalf of the governing body? ............
8b
Yes
 
9
Is there any officer, director, trustee, or key employee listed in Part VII, Section A, who cannot be reached at the organization’s mailing address? If "Yes," provide the names and addresses in Schedule O.......
9
 
No
Section B. Policies (This Section B requests information about policies not required by the Internal Revenue Code.)
Yes
No
10a
Did the organization have local chapters, branches, or affiliates? ............
10a
 
No
b
If "Yes," did the organization have written policies and procedures governing the activities of such chapters, affiliates, and branches to ensure their operations are consistent with the organization's exempt purposes?
10b
 
 
11a
Has the organization provided a complete copy of this Form 990 to all members of its governing body before filing the form? ............................
11a
Yes
 
b
Describe on Schedule O the process, if any, used by the organization to review this Form 990. .....
12a
Did the organization have a written conflict of interest policy? If "No," go to line 13.......
12a
Yes
 
b
Were officers, directors, or trustees, and key employees required to disclose annually interests that could give rise to conflicts? ..........................
12b
Yes
 
c
Did the organization regularly and consistently monitor and enforce compliance with the policy? If "Yes," describe on Schedule O how this was done...................
12c
Yes
 
13
Did the organization have a written whistleblower policy? ...............
13
Yes
 
14
Did the organization have a written document retention and destruction policy? .........
14
Yes
 
15
Did the process for determining compensation of the following persons include a review and approval by independent persons, comparability data, and contemporaneous substantiation of the deliberation and decision?
a
The organization’s CEO, Executive Director, or top management official ...........
15a
Yes
 
b
Other officers or key employees of the organization ................
15b
Yes
 
If "Yes" to line 15a or 15b, describe the process on Schedule O. See instructions.
16a
Did the organization invest in, contribute assets to, or participate in a joint venture or similar arrangement with a taxable entity during the year? ......................
16a
 
No
b
If "Yes," did the organization follow a written policy or procedure requiring the organization to evaluate its participation in joint venture arrangements under applicable federal tax law, and take steps to safeguard the organization’s exempt status with respect to such arrangements? ............
16b
 
 
Section C. Disclosure
17
List the states with which a copy of this Form 990 is required to be filedMediumBullet
CA , IL , IN , MA , NY , OR
18
Section 6104 requires an organization to make its Form 1023 (1024 or 1024-A, if applicable), 990, and 990-T (section 501(c)(3)s only) available for public inspection. Indicate how you made these available. Check all that apply.
19
Describe in Schedule O whether (and if so, how) the organization made its governing documents, conflict of interest policy, and financial statements available to the public during the tax year.
20
State the name, address, and telephone number of the person who possesses the organization's books and records:
MediumBulletLYNNE LOCHTE4000 JONES BRIDGE ROAD   CHEVY CHASE,MD20815 (301) 215-8500
Form 990 (2021)
Form 990 (2021)
Page 7
Part VII
Compensation of Officers, Directors,Trustees, Key Employees, Highest Compensated Employees, and Independent Contractors
Check if Schedule O contains a response or note to any line in this Part VII..............
Section A. Officers, Directors, Trustees, Key Employees, and Highest Compensated Employees
1a Complete this table for all persons required to be listed. Report compensation for the calendar year ending with or within the organization’s tax year.
RoundBullet List all of the organization’s current officers, directors, trustees (whether individuals or organizations), regardless of amount
of compensation. Enter -0- in columns (D), (E), and (F) if no compensation was paid.

RoundBullet List all of the organization’s current key employees, if any. See the instructions for definition of "key employee."
RoundBullet List the organization’s five current highest compensated employees (other than an officer, director, trustee or key employee)
who received reportable compensation (box 5 of Form W-2, Form 1099-MISC, and/or box 1 of Form 1099-NEC) of more than $100,000 from the
organization and any related organizations.

RoundBullet List all of the organization’s former officers, key employees, or highest compensated employees who received more than $100,000
of reportable compensation from the organization and any related organizations.

RoundBullet List all of the organization’s former directors or trustees that received, in the capacity as a former director or trustee of the
organization, more than $10,000 of reportable compensation from the organization and any related organizations.

See the instructions for the order in which to list the persons above.
Check this box if neither the organization nor any related organization compensated any current officer, director, or trustee.
(A)
Name and title
(B)
Average hours per week (list any hours for related organizations below dotted line)
(C)
Position (do not check more than one box, unless person is both an officer and a director/trustee)
(D)
Reportable compensation from the organization (W-2/1099-MISC/1099-NEC)
(E)
Reportable compensation from related organizations (W-2/1099-MISC/1099-NEC)
(F)
Estimated amount of other compensation from the organization and related organizations
Individual Trustee or Director; Institutional Trustee; OfficerInd; Key Employee; Highest compensated employee; FormerOfcrDirectorTrusteeInd;
(1) ALISON F RICHARD PHD
 
TRUSTEE, CHAIR EDUCATION COMM
4.0
.................
0.0
X           60,000 0 0
(2) CHARLENE BARSHEFSKY ESQ
 
TRUSTEE, CHAIR NOM & GOV COMM
4.0
.................
0.0
X           60,000 0 0
(3) CLAYTON S ROSE PHD
 
TRUSTEE, CHAIR
6.0
.................
0.0
X           80,000 0 0
(4) DAVID JULIUS PHD
 
TRUSTEE
2.0
.................
0.0
X           53,789 0 0
(5) DEBORA L SPAR PHD
 
TRUSTEE, CHAIR AUDIT & COMP
4.0
.................
0.0
X           60,000 0 0
(6) FRED R LUMMIS
 
TRUSTEE, CHAIR FINANCE COMM
4.0
.................
0.0
X           60,000 0 0
(7) JOSEPH L GOLDSTEIN MD
 
TRUSTEE, CHAIR RESEARCH COMM
4.0
.................
0.0
X           60,000 0 0
(8) KURT L SCHMOKE ESQ
 
TRUSTEE
2.0
.................
0.0
X           50,000 0 0
(9) MARGARET D TUTWILER
 
TRUSTEE
2.0
.................
0.0
X           50,000 0 0
(10) PAUL M NURSE PHD
 
TRUSTEE
2.0
.................
0.0
X           50,000 0 0
(11) RISA LAVIZZO-MOUREY MD MBA
 
TRUSTEE
2.0
.................
0.0
X           50,874 0 0
(12) ANN K BATLLE ESQ
 
DEPUTY GENERAL COUNSEL & ASSISTANT SECRETARY (AS OF 1/22)
40.0
.................
0.0
    X       282,828 0 61,989
(13) BODO STERN PHD
 
CHIEF OF STRATEGIC INITIATIVES
40.0
.................
0.0
    X       405,649 0 45,026
(14) DANIEL A CRONIN MBA PHD
 
VP & CHIEF FINANCIAL & OPERATING OFFICER
40.0
.................
0.0
    X       713,924 0 41,906
(15) DAVID E CLAPHAM PHD
 
VP & CHIEF SCIENTIFIC OFFICER (THRU 1/22)/SENIOR GROUP LEADER
40.0
.................
0.0
    X       782,127 0 71,809
(16) DONALD KOCH
 
VP & CHIEF INVESTMENT OFFICER
40.0
.................
0.0
    X       1,379,324 0 68,162
(17) ERIN K O'SHEA PHD
 
PRESIDENT
40.0
.................
0.0
    X       1,484,549 0 64,350
Form 990 (2021)
Form 990 (2021)
Page 8
Part VII
Section A. Officers, Directors, Trustees, Key Employees, and Highest Compensated Employees (continued)
(A)
Name and title
(B)
Average hours per week (list any hours for related organizations below dotted line)
(C)
Position (do not check more than one box, unless person is both an officer and a director/trustee)
(D)
Reportable compensation from the organization (W-2/1099-MISC/1099-NEC)
(E)
Reportable compensation from related organizations (W-2/1099-MISC/1099-NEC)
(F)
Estimated amount of other compensation from the organization and related organizations
Individual Trustee or Director; Institutional Trustee; OfficerInd; Key Employee; Highest compensated employee; FormerOfcrDirectorTrusteeInd;
(18) HEIDI E HENNING ESQ
 
VP & GENERAL COUNSEL & SECRETARY
40.0
.......................0.0
    X       730,121 0 71,604
(19) JEREMY COMPTON
 
ASSOCIATE COMPTROLLER (AS OF 5/22)
40.0
.......................0.0
    X       177,383 0 29,037
(20) LAUREN T SPILIOTES ESQ
 
DEPUTY GENERAL COUNSEL & ASSISTANT SECRETARY (THRU 1/22)
40.0
.......................0.0
    X       487,926 0 57,209
(21) LESLIE B VOSSHALL PHD
 
INVESTIGATOR/VP & CHIEF SCIENTIFIC OFFICER (AS OF 2/22)
40.0
.......................0.0
    X       712,516 0 65,832
(22) LYNNE LOCHTE
 
DEPUTY CHIEF FINANCIAL OFFICER & ASSISTANT TREASURER (AS OF 8/22)
40.0
.......................0.0
    X       0 0 0
(23) MONIQUE L MARCUS
 
CONTROLLER
40.0
.......................0.0
    X       242,818 0 60,516
(24) RONALD VALE PHD
 
VP & EXEC DIR, JANELIA RESEARCH CAMPUS
40.0
.......................0.0
    X       765,571 0 63,866
(25) SEAN B CARROLL PHD
 
VP FOR SCIENCE EDUCATION
40.0
.......................0.0
    X       811,334 0 56,642
(26) SUSAN S PLOTNICK
 
DIRECTOR OF FINANCE & ASSISTANT TREASURER (THRU 6/22)
40.0
.......................0.0
    X       266,862 0 58,102
(27) ERIC KANDEL MD
 
INVESTIGATOR
40.0
.......................0.0
        X   823,607 0 70,910
(28) GLEN ZWICKER
 
MANAGING DIRECTOR & HEAD OF INVESTMENT OPS
40.0
.......................0.0
        X   996,843 0 67,298
(29) GREGORY DENINNO
 
MANAGING DIRECTOR, PRIVATE MARKETS
40.0
.......................0.0
        X   1,279,721 0 50,754
(30) LANDIS ZIMMERMAN
 
VP & CHIEF INVESTMENT OFFICER (THRU 6/21)
40.0
.......................0.0
        X   1,588,435 0 46,481
(31) RICHARD A PENDER
 
MANAGING DIRECTOR, PUBLIC MARKETS
40.0
.......................0.0
        X   1,480,088 0 64,173
(32) DENNIS MCKEARIN PHD
 
SENIOR SCIENTIFIC OFFICER/FORMER VP OF OPERATIONS
40.0
.......................0.0
          X 444,903 0 62,548
(33) GERALD M RUBIN PHD
 
SENIOR GROUP LEADER/FORMER VP&EXEC DIR, JRC
40.0
.......................0.0
          X 564,261 0 65,745
(34) ROBERT J KOLYER JR
 
MANAGING DIRECTOR, DIVERSIFYING ASSETS (THRU 6/21)
40.0
.......................0.0
          X 753,975 0 48,862
1b Sub-Total................MediumBullet
c Total from continuation sheets to Part VII, Section A....MediumBullet
d Total (add lines 1b and 1c)...........MediumBullet 17,809,428 0 1,292,821
2
Total number of individuals (including but not limited to those listed above) who received more than $100,000 of reportable compensation from the organization MediumBullet734
Yes
No
3
Did the organization list any former officer, director or trustee, key employee, or highest compensated employee on line 1a? If "Yes," complete Schedule J for such individual ..............
3
Yes
 
4
For any individual listed on line 1a, is the sum of reportable compensation and other compensation from the organization and related organizations greater than $150,000? If "Yes," complete Schedule J for such
individual
...........................
4
Yes
 
5
Did any person listed on line 1a receive or accrue compensation from any unrelated organization or individual for services rendered to the organization? If "Yes," complete Schedule J for such person ........
5
 
No
Section B. Independent Contractors
1
Complete this table for your five highest compensated independent contractors that received more than $100,000 of compensation from the organization. Report compensation for the calendar year ending with or within the organization’s tax year.
(A)
Name and business address
(B)
Description of services
(C)
Compensation
ECHO STREET CAPITAL MGR LLC (VIA HHMI II LLC)

850 THIRD AVENUE
NEW YORK,NY10022
INVESTMENT MGT 8,686,752
ARAMARK HARRISON LODGING

1101 MARKET ST
PHILADELPHIA,PA19107
CONFERENCE CTR MGT 4,648,392
HOLDCO ASSET MANAGEMENT LP

300 SE 2ND STREET SUITE 600
FORT LAUDERDALE,FL33301
INVESTMENT MGT 4,103,896
SELECT EQUITY GROUP INC (VIA SPRUGOS INVESTMENTS III LLC)

380 LAFEYETTE STREET
NEW YORK,NY10003
INVESTMENT MGT 3,454,874
JONES LANG LASALLE AMERICAS INC

525 WILLIAM PENN PLACE
PITTSBURGH,PA15259
FACILITIES MGT 3,250,566
2
Total number of independent contractors (including but not limited to those listed above) who received more than $100,000 of compensation from the organization MediumBullet151
Form 990 (2021)
Form 990 (2021)
Page 9
Part VIII
Statement of Revenue
Check if Schedule O contains a response or note to any line in this Part VIII.............
(A)
Total revenue
(B)
Related or
exempt
function
revenue
(C)
Unrelated
business
revenue
(D)
Revenue
excluded from
tax under sections
512 - 514
Contributions, Gifts, Grants, and OtherAmt Similar Amounts 1a Federated campaigns..1a  
b Membership dues..1b  
c Fundraising events..1c  
d Related organizations1d  
e Government grants (contributions)1e  
f All other contributions, gifts, grants, and similar amounts not included above1f 2,025,577
g Noncash contributions included in lines 1a - 1f:$ 1g  
h Total. Add lines 1a-1f.......MediumBullet 2,025,577
 Program Service RevenueAmt Business Code
2a RENTAL INCOME 900099 2,702,904 2,702,904    
b TV & FILM INCOME 900099 1,162,470 1,162,470    
c
d
e
f All other program service revenue. 0 0 0 0
g Total. Add lines 2a–2f .....MediumBullet 3,865,374
 OtherAmtRevenueAmt 3 Investment income (including dividends, interest, and othersimilar amounts) ......MediumBullet 242,965,427   10,318,031 232,647,396
4 Income from investment of tax-exempt bond proceedsMediumBullet        
5 Royalties...........MediumBullet 23,989,529     23,989,529
(ii) Personal (i) Real
6a Gross rents   180,694 6a
b Less: rental expenses   433,768 6b
c Rental income or (loss) 0 -253,074 6c
d Net rental income or (loss).......MediumBullet -253,074   -143,934 -109,140
(ii) Other (i) Securities
7a Gross amount from sales of assets other than inventory 68,832,432 24,432,100,973 7a
b Less: cost or other basis and sales expenses   22,656,443,933 7b
c Gain or (loss) 68,832,432 1,775,657,040 7c
d Net gain or (loss).........MediumBullet 1,844,489,472   68,761,346 1,775,728,126
8a Gross income from fundraising events (not including $   of contributions reported on line 1c). See Part IV, line 18 ....
8a  
b Less: direct expenses ... 8b  
c Net income or (loss) from fundraising events..MediumBullet      
9a Gross income from gaming activities.
See Part IV, line 19 ...
9a  
b Less: direct expenses ... 9b  
c Net income or (loss) from gaming activities..MediumBullet        
10a Gross sales of inventory, less
returns and allowances ..
10a  
b Less: cost of goods sold .. 10b  
c Net income or (loss) from sales of inventory..MediumBullet        
Business Code Miscellaneous Revenue
11a CAFETERIA 900099 81,390     81,390
b INVESTMENT EXPENSE REBATE 900099 46,015     46,015
c CASH DISCOUNTS 900099 252,626     252,626
d All other revenue .... 15,221 0 0 15,221
e Total. Add lines 11a–11d ...... MediumBullet 395,252
12 Total revenue. See instructions.....MediumBullet 2,117,477,557 3,865,374 78,935,443 2,032,651,163
Form 990 (2021)
Form 990 (2021)
Page 10
Part IX
Statement of Functional Expenses
Section 501(c)(3) and 501(c)(4) organizations must complete all columns. All other organizations must complete column (A).Check if Schedule O contains a response or note to any line in this Part IX..............
Do not include amounts reported on lines 6b,
7b, 8b, 9b, and 10b of Part VIII.
(A)
Total expenses
(B)
Program service expenses
(C)
Management and general expenses
(D)
Fundraising
expenses
1 Grants and other assistance to domestic organizations and domestic governments. See Part IV, line 21 .... 21,028,136 21,028,136
2 Grants and other assistance to domestic individuals. See Part IV, line 22 ........... 8,563,780 8,563,780
3 Grants and other assistance to foreign organizations, foreign governments, and foreign individuals. See Part IV, lines 15 and 16. ............. 576,620 576,620
4 Benefits paid to or for members .......    
5 Compensation of current officers, directors, trustees, and key employees ........... 11,626,166 3,394,029 8,232,137  
6 Compensation not included above, to disqualified persons (as defined under section 4958(f)(1)) and persons described in section 4958(c)(3)(B) ......... 2,730,504 1,285,292 1,445,212  
7 Other salaries and wages........ 303,929,508 258,757,393 45,172,115  
8 Pension plan accruals and contributions (include section 401(k) and 403(b) employer contributions) .... 22,581,188 18,925,973 3,655,215  
9 Other employee benefits ....... 39,604,133 34,055,707 5,548,426  
10 Payroll taxes ........... 17,825,205 15,168,845 2,656,360  
11 Fees for services (non-employees):        
a Management ......        
b Legal ......... 11,285,114 884,711 10,400,403  
c Accounting ........... 1,052,947   1,052,947  
d Lobbying ........... 112,500   112,500  
e Professional fundraising services. See Part IV, line 17    
f Investment management fees ...... 90,145,587   90,145,587  
g Other (If line 11g amount exceeds 10% of line 25, column (A) amount, list line 11g expenses on Schedule O) 55,460,809 43,282,481 12,178,328 0
12 Advertising and promotion ....        
13 Office expenses ....... 4,411,210 2,466,379 1,944,831  
14 Information technology ...... 12,048,814 6,558,437 5,490,377  
15 Royalties .. 7,221 7,221    
16 Occupancy ........... 80,539,234 70,677,886 9,861,348  
17 Travel ............ 4,531,718 4,108,440 423,278  
18 Payments of travel or entertainment expenses for any federal, state, or local public officials .        
19 Conferences, conventions, and meetings .... 4,140,903 2,264,884 1,876,019  
20 Interest ........... 23,016,975 15,392,785 7,624,190  
21 Payments to affiliates .......        
22 Depreciation, depletion, and amortization .. 92,297,945 82,841,459 9,456,486  
23 Insurance ... 432,647 39,878 392,769  
24 Other expenses. Itemize expenses not covered above (List miscellaneous expenses in line 24e. If line 24e amount exceeds 10% of line 25, column (A) amount, list line 24e expenses on Schedule O.)
a LAB & OTHER SCIENTIFIC SUPPLIES 122,109,374 121,004,330 1,105,044  
b MINOR EQUIPMENT & RENOVATIONS 11,436,490 10,914,174 522,316  
c EQUIPMENT MAINTENANCE 20,669,349 14,706,304 5,963,045  
d INCOME TAX 867,173   867,173  
e All other expenses 23,258,705 15,699,106 7,559,599 0
25 Total functional expenses. Add lines 1 through 24e 986,289,955 752,604,250 233,685,705 0
26 Joint costs. Complete this line only if the organization reported in column (B) joint costs from a combined educational campaign and fundraising solicitation. Check here MediumBullet if following SOP 98-2 (ASC 958-720).        
Form 990 (2021)
Form 990 (2021)
Page 11
Part X
Balance Sheet
Check if Schedule O contains a response or note to any line in this Part IX..............
(A)
Beginning of year
(B)
End of year
Assets 1 Cash–non-interest-bearing ........   1  
2 Savings and temporary cash investments ......... 747,886,828 2 605,170,460
3 Pledges and grants receivable, net ......   3  
4 Accounts receivable, net .............   4  
5 Loans and other receivables from any current or former officer, director, trustee, key employee, creator or founder, substantial contributor, or 35% controlled entity or family member of any of these persons .......
0 5 0
6 Loans and other receivables from other disqualified persons (as defined under section 4958(f)(1)), and persons described in section 4958(c)(3)(B) ...
0 6 0
7 Notes and loans receivable, net ...........   7  
8 Inventories for sale or use ............   8  
9 Prepaid expenses and deferred charges ...... 32,273,109 9 21,448,119
10a Land, buildings, and equipment: cost or other basis. Complete Part VI of Schedule D 10a 2,126,076,342
b Less: accumulated depreciation 10b 1,285,406,382 765,037,142 10c 840,669,960
11 Investments—publicly traded securities . 5,687,314,187 11 4,804,986,772
12 Investments—other securities. See Part IV, line 11 ..... 21,361,667,853 12 18,893,785,554
13 Investments—program-related. See Part IV, line 11 .. 0 13  
14 Intangible assets ...............   14  
15 Other assets. See Part IV, line 11 ........... 748,928,644 15 711,331,789
16 Total assets. Add lines 1 through 15 (must equal line 33)... 29,343,107,763 16 25,877,392,654
Liabilities 17 Accounts payable and accrued expenses ..... 343,309,373 17 257,691,395
18 Grants payable ... 59,666,530 18 36,751,271
19 Deferred revenue .........   19  
20 Tax-exempt bond liabilities ......... 771,935,538 20 773,837,678
21 Escrow or custodial account liability. Complete Part IV of Schedule D   21  
22 Loans and other payables to any current or former officer, director, trustee, key employee, creator or founder, substantial contributor, or 35% controlled entity or family member of any of these persons .........
0 22 0
23 Secured mortgages and notes payable to unrelated third parties ..   23  
24 Unsecured notes and loans payable to unrelated third parties .. 39,390,298 24 39,428,489
25 Other liabilities (including federal income tax, payables to related third parties, and other liabilities not included on lines 17 - 24). Complete Part X of Schedule D 1,029,871,412 25 730,014,837
26 Total liabilities. Add lines 17 through 25.. 2,244,173,151 26 1,837,723,670
Net Assets or Fund Balance Organizations that follow FASB ASC 958, check here MediumBullet and complete lines 27, 28, 32, and 33.
27 Net assets without donor restrictions .......... 27,098,934,612 27 24,039,668,984
28 Net assets with donor restrictions ...........   28  
Organizations that do not follow FASB ASC 958, check here MediumBullet and complete lines 29 through 33.
29 Capital stock or trust principal, or current funds .....   29  
30 Paid-in or capital surplus, or land, building or equipment fund ...   30  
31 Retained earnings, endowment, accumulated income, or other funds   31  
32 Total net assets or fund balances ........... 27,098,934,612 32 24,039,668,984
33 Total liabilities and net assets/fund balances ........ 29,343,107,763 33 25,877,392,654
Form 990 (2021)
Form 990 (2021)
Page 12
Part XI
Reconcilliation of Net Assets
Check if Schedule O contains a response or note to any line in this Part XI..............
1
Total revenue (must equal Part VIII, column (A), line 12) ............
1
2,117,477,557
2
Total expenses (must equal Part IX, column (A), line 25) ............
2
986,289,955
3
Revenue less expenses. Subtract line 2 from line 1 ..............
3
1,131,187,602
4
Net assets or fund balances at beginning of year (must equal Part X, line 32, column (A)) ..
4
27,098,934,612
5
Net unrealized gains (losses) on investments ...............
5
-4,304,957,036
6
Donated services and use of facilities .................
6
 
7
Investment expenses .....................
7
 
8
Prior period adjustments .....................
8
 
9
Other changes in net assets or fund balances (explain in Schedule O) ........
9
114,503,806
10
Net assets or fund balances at end of year. Combine lines 3 through 9 (must equal Part X, line 32, column (B))
10
24,039,668,984
Part XII
Financial Statements and Reporting
Check if Schedule O contains a response or note to any line in this Part XII.............
Yes
No
1
Accounting method used to prepare the Form 990:  
If the organization changed its method of accounting from a prior year or checked "Other," explain on
Schedule O.
2a
Were the organization’s financial statements compiled or reviewed by an independent accountant?
2a
 
No
If ‘Yes,’ check a box below to indicate whether the financial statements for the year were compiled or reviewed on a separate basis, consolidated basis, or both:
b
Were the organization’s financial statements audited by an independent accountant?
2b
Yes
 
If ‘Yes,’ check a box below to indicate whether the financial statements for the year were audited on a separate basis, consolidated basis, or both:
c
If "Yes," to line 2a or 2b, does the organization have a committee that assumes responsibility for oversight of the audit, review, or compilation of its financial statements and selection of an independent accountant?
2c
Yes
 
If the organization changed either its oversight process or selection process during the tax year, explain in Schedule O.
3a
As a result of a federal award, was the organization required to undergo an audit or audits as set forth in the Single Audit Act and OMB Circular A-133?
3a
 
No
b
If "Yes," did the organization undergo the required audit or audits? If the organization did not undergo the required audit or audits, explain why in Schedule O and describe any steps taken to undergo such audits.
3b
 
 
Form 990 (2021)
Form 990 (2021)
Additional Data


Software ID: 21014044
Software Version: 2021v4.2
Form 990, Special Condition Description:
Special Condition Description
SCHEDULE A
(Form 990)

Department of the Treasury
Internal Revenue Service
Public Charity Status and Public Support
Complete if the organization is a section 501(c)(3) organization or a section 4947(a)(1) nonexempt charitable trust.
right arrow Attach to Form 990 or Form 990-EZ.
right arrow Go to www.irs.gov/Form990 for instructions and the latest information.
OMB No. 1545-0047
2021
Open to Public
Inspection
Name of the organization
Howard Hughes Medical Institute
 
Employer identification number

59-0735717
Part I
Reason for Public Charity Status (All organizations must complete this part.) See instructions.
The organization is not a private foundation because it is: (For lines 1 through 12, check only one box.)
1
2
3
4
5
6
7
8
9
10
11
12
a
b
c
d
e
f
Enter the number of supported organizations ...............................  
g
Provide the following information about the supported organization(s).
(i) Name of supported organization (ii) EIN (iii) Type of organization (described on lines 1- 10 above (see instructions)) (iv) Is the organization listed in your governing document? (v) Amount of monetary support (see instructions) (vi) Amount of other support (see instructions)
Yes No
Total
 
   
For Paperwork Reduction Act Notice, see the Instructions for
Form 990 or 990-EZ.
Cat. No. 11285F
Schedule A (Form 990) 2021

Schedule A (Form 990) 2021
Page 2
Part II
Support Schedule for Organizations Described in Sections 170(b)(1)(A)(iv) and 170(b)(1)(A)(vi)
(Complete only if you checked the box on line 5, 7, or 8 of Part I or if the organization failed to qualify under Part III. If the organization failed to qualify under the tests listed below, please complete Part III.)
Section A. Public Support
Calendar year (or fiscal year beginning in) right arrow (a) 2017 (b) 2018 (c) 2019 (d) 2020 (e) 2021 (f) Total
1 Gifts, grants, contributions, and membership fees received. (Do not include any "unusual grant.") ..            
2 Tax revenues levied for the organization's benefit and either paid to or expended on its behalf....            
3 The value of services or facilities furnished by a governmental unit to the organization without charge..            
4 Total. Add lines 1 through 3            
5 The portion of total contributions by each person (other than a governmental unit or publicly supported organization) included on line 1 that exceeds 2% of the amount shown on line 11, column (f) ..  
6 Public support. Subtract line 5 from line 4.  
Section B. Total Support
Calendar year (or fiscal year beginning in) right arrow (a) 2017 (b) 2018 (c) 2019 (d) 2020 (e) 2021 (f) Total
7 Amounts from line 4..            
8 Gross income from interest, dividends, payments received on securities loans, rents, royalties and income from similar sources...            
9 Net income from unrelated business activities, whether or not the business is regularly carried on..            
10 Other income. Do not include gain or loss from the sale of capital assets (Explain in Part VI.)..            
11 Total support. Add lines 7 through 10  
12
12
 
13
First 5 years. If the Form 990 is for the organization's first, second, third, fourth, or fifth tax year as a section 501(c)(3) organization, check this box and stop here ........................................right arrow
Section C. Computation of Public Support Percentage
14
14
 
15
15
 
16a
b
17a
b
18
Private foundation. If the organization did not check a box on line 13, 16a, 16b, 17a, or 17b, check this box and see
instructions ..................................................... right arrow
Schedule A (Form 990) 2021

Schedule A (Form 990) 2021
Page 3
Part III
Support Schedule for Organizations Described in Section 509(a)(2)
(Complete only if you checked the box on line 10 of Part I or if the organization failed to qualify under Part II. If the organization fails to qualify under the tests listed below, please complete Part II.)
Section A. Public Support
Calendar year (or fiscal year beginning in) right arrow (a) 2017 (b) 2018 (c) 2019 (d) 2020 (e) 2021 (f) Total
1 Gifts, grants, contributions, and membership fees received. (Do not include any "unusual grants.") .            
2 Gross receipts from admissions, merchandise sold or services performed, or facilities furnished in any activity that is related to the organization's tax-exempt purpose            
3 Gross receipts from activities that are not an unrelated trade or business under section 513 .....            
4 Tax revenues levied for the organization's benefit and either paid to or expended on its behalf...            
5 The value of services or facilities furnished by a governmental unit to the organization without charge            
6 Total. Add lines 1 through 5            
7a Amounts included on lines 1, 2, and 3 received from disqualified persons            
b Amounts included on lines 2 and 3 received from other than disqualified persons that exceed the greater of $5,000 or 1% of the amount on line 13 for the year.            
c Add lines 7a and 7b..            
8 Public support. (Subtract line 7c from line 6.)  
Section B. Total Support
Calendar year (or fiscal year beginning in) right arrow (a) 2017 (b) 2018 (c) 2019 (d) 2020 (e) 2021 (f) Total
9 Amounts from line 6...            
10a Gross income from interest, dividends, payments received on securities loans, rents, royalties and income from similar sources..            
b Unrelated business taxable income (less section 511 taxes) from businesses acquired after June 30, 1975.            
c Add lines 10a and 10b.            
11 Net income from unrelated business activities not included on line 10b, whether or not the business is regularly carried on.            
12 Other income. Do not include gain or loss from the sale of capital assets (Explain in Part VI.) ..            
13 Total support. (Add lines 9, 10c, 11, and 12.)..            
14
Section C. Computation of Public Support Percentage
15
15
 
16
16
 
Section D. Computation of Investment Income Percentage
17
17
 
18
18
 
19a
b
20
Schedule A (Form 990) 2021

Schedule A (Form 990) 2021
Page 4
Part IV
Supporting Organizations
(Complete only if you checked a box on line 12 of Part I. If you checked box 12a, of Part I, complete Sections A and B. If you checked box 12b, of Part I, complete Sections A and C. If you checked box 12c, of Part I, complete Sections A, D, and E. If you checked box12d, of Part I, complete Sections A and D, and complete Part V.)
Section A. All Supporting Organizations
Yes
No
1
Are all of the organization’s supported organizations listed by name in the organization’s governing documents?
If "No," describe in Part VI how the supported organizations are designated. If designated by class or purpose,
describe the designation. If historic and continuing relationship, explain.
1
 
 
2
Did the organization have any supported organization that does not have an IRS determination of status under section 509(a)(1) or (2)? If "Yes," explain in Part VI how the organization determined that the supported organization was described in section 509(a)(1) or (2).
2
 
 
3a
Did the organization have a supported organization described in section 501(c)(4), (5), or (6)? If "Yes," answer lines 3b and 3c below.
3a
 
 
b
Did the organization confirm that each supported organization qualified under section 501(c)(4), (5), or (6) and satisfied the public support tests under section 509(a)(2)? If "Yes," describe in Part VI when and how the organization made the determination.
3b
 
 
c
Did the organization ensure that all support to such organizations was used exclusively for section 170(c)(2)(B) purposes? If "Yes," explain in Part VI what controls the organization put in place to ensure such use.
3c
 
 
4a
Was any supported organization not organized in the United States ("foreign supported organization")? If “Yes” and if you checked box 12a or 12b in Part I, answer lines 4b and 4c below.
4a
 
 
b
Did the organization have ultimate control and discretion in deciding whether to make grants to the foreign supported organization? If “Yes,” describe in Part VI how the organization had such control and discretion despite being controlled or supervised by or in connection with its supported organizations.
4b
 
 
c
Did the organization support any foreign supported organization that does not have an IRS determination under sections 501(c)(3) and 509(a)(1) or (2)? If “Yes,” explain in Part VI what controls the organization used to ensure that all support to the foreign supported organization was used exclusively for section 170(c)(2)(B) purposes.
4c
 
 
5a
Did the organization add, substitute, or remove any supported organizations during the tax year? If “Yes,” answer lines 5b and 5c below (if applicable). Also, provide detail in Part VI, including (i) the names and EIN numbers of the supported organizations added, substituted, or removed; (ii) the reasons for each such action; (iii) the authority under the organization's organizing document authorizing such action; and (iv) how the action was accomplished (such as by amendment to the organizing document).
5a
 
 
b
Type I or Type II only. Was any added or substituted supported organization part of a class already designated in the organization's organizing document?
5b
 
 
c
Substitutions only. Was the substitution the result of an event beyond the organization's control?
5c
 
 
6
Did the organization provide support (whether in the form of grants or the provision of services or facilities) to anyone other than (i) its supported organizations, (ii) individuals that are part of the charitable class benefited by one or more of its supported organizations, or (iii) other supporting organizations that also support or benefit one or more of the filing organization’s supported organizations? If “Yes,” provide detail in Part VI.
6
 
 
7
Did the organization provide a grant, loan, compensation, or other similar payment to a substantial contributor (defined in section 4958(c)(3)(C)), a family member of a substantial contributor, or a 35% controlled entity with regard to a substantial contributor? If “Yes,” complete Part I of Schedule L (Form 990) .
7
 
 
8
Did the organization make a loan to a disqualified person (as defined in section 4958) not described on line 7? If “Yes,” complete Part I of Schedule L (Form 990).
8
 
 
9a
Was the organization controlled directly or indirectly at any time during the tax year by one or more disqualified persons, as defined in section 4946 (other than foundation managers and organizations described in section 509(a)(1) or (2))? If “Yes,” provide detail in Part VI.
9a
 
 
b
Did one or more disqualified persons (as defined on line 9a) hold a controlling interest in any entity in which the supporting organization had an interest? If “Yes,” provide detail in Part VI.
9b
 
 
c
Did a disqualified person (as defined on line 9a) have an ownership interest in, or derive any personal benefit from, assets in which the supporting organization also had an interest? If “Yes,” provide detail in Part VI.
9c
 
 
10a
Was the organization subject to the excess business holdings rules of section 4943 because of section 4943(f) (regarding certain Type II supporting organizations, and all Type III non-functionally integrated supporting organizations)? If “Yes,” answer line 10b below.
10a
 
 
b
Did the organization have any excess business holdings in the tax year? (Use Schedule C, Form 4720, to determine whether the organization had excess business holdings).
10b
 
 
Schedule A (Form 990) 2021

Schedule A (Form 990) 2021
Page 5
Part IV
Supporting Organizations (continued)
Yes
No
11
Has the organization accepted a gift or contribution from any of the following persons?
a
A person who directly or indirectly controls, either alone or together with persons described on lines 11b and 11c below, the governing body of a supported organization?
11a
 
 
b
A family member of a person described on 11a above?
11b
 
 
c
A 35% controlled entity of a person described on line 11a or 11b above? If “Yes” to 11a, 11b, or 11c, provide detail in Part VI.
11c
 
 
Section B. Type I Supporting Organizations
Yes
No
1
Did the officers, directors, trustees, or membership of one or more supported organizations have the power to regularly appoint or elect at least a majority of the organization’s directors or trustees at all times during the tax year? If “No,” describe in Part VI how the supported organization(s) effectively operated, supervised, or controlled the organization’s activities. If the organization had more than one supported organization, describe how the powers to appoint and/or remove directors or trustees were allocated among the supported organizations and what conditions or restrictions, if any, applied to such powers during the tax year.
1
 
 
2
Did the organization operate for the benefit of any supported organization other than the supported organization(s) that operated, supervised, or controlled the supporting organization? If “Yes,” explain in Part VI how providing such benefit carried out the purposes of the supported organization(s) that operated, supervised or controlled the supporting organization.
2
 
 
Section C. Type II Supporting Organizations
Yes
No
1
Were a majority of the organization’s directors or trustees during the tax year also a majority of the directors or trustees of each of the organization’s supported organization(s)? If “No,” describe in Part VI how control or management of the supporting organization was vested in the same persons that controlled or managed the supported organization(s).
1
 
 
Section D. All Type III Supporting Organizations
Yes
No
1
Did the organization provide to each of its supported organizations, by the last day of the fifth month of the organization’s tax year, (i) a written notice describing the type and amount of support provided during the prior tax year, (ii) a copy of the Form 990 that was most recently filed as of the date of notification, and (iii) copies of the organization’s governing documents in effect on the date of notification, to the extent not previously provided?
1
 
 
2
Were any of the organization’s officers, directors, or trustees either (i) appointed or elected by the supported organization(s) or (ii) serving on the governing body of a supported organization? If "No," explain in Part VI how the organization maintained a close and continuous working relationship with the supported organization(s).
2
 
 
3
By reason of the relationship described in line 2 above, did the organization’s supported organizations have a significant voice in the organization’s investment policies and in directing the use of the organization’s income or assets at all times during the tax year? If "Yes," describe in Part VI the role the organization’s supported organizations played in this regard.
3
 
 
Section E. Type III Functionally-Integrated Supporting Organizations
1
Check the box next to the method that the organization used to satisfy the Integral Part Test during the year (see instructions):
a
b
c
2
Activities Test. Answer lines 2a and 2b below.
Yes
No
a
Did substantially all of the organization’s activities during the tax year directly further the exempt purposes of the supported organization(s) to which the organization was responsive? If "Yes," then in Part VI identify those supported organizations and explain how these activities directly furthered their exempt purposes, how the organization was responsive to those supported organizations, and how the organization determined that these activities constituted substantially all of its activities.
2a
 
 
b
Did the activities described on line 2a, above constitute activities that, but for the organization’s involvement, one or more of the organization’s supported organization(s) would have been engaged in? If "Yes," explain in Part VI the reasons for the organization’s position that its supported organization(s) would have engaged in these activities but for the organization’s involvement.
2b
 
 
3
Parent of Supported Organizations. Answer lines 3a and 3b below.
a
Did the organization have the power to regularly appoint or elect a majority of the officers, directors, or trustees of each of the supported organizations?If "Yes" or "No", provide details in Part VI.
3a
 
 
b
Did the organization exercise a substantial degree of direction over the policies, programs and activities of each of its supported organizations? If "Yes," describe in Part VI. the role played by the organization in this regard.
3b
 
 
Schedule A (Form 990) 2021

Schedule A (Form 990) 2021
Page 6
Part V
Type III Non-Functionally Integrated 509(a)(3) Supporting Organizations
1
Section A - Adjusted Net Income (A) Prior Year (B) Current Year
(optional)
1 Net short-term capital gain 1    
2 Recoveries of prior-year distributions 2    
3 Other gross income (see instructions) 3    
4 Add lines 1 through 3 4    
5 Depreciation and depletion 5    
6 Portion of operating expenses paid or incurred for production or collection of gross income or for management, conservation, or maintenance of property held for production of income (see instructions) 6    
7 Other expenses (see instructions) 7    
8 Adjusted Net Income (subtract lines 5, 6 and 7 from line 4) 8    
Section B - Minimum Asset Amount (A) Prior Year (B) Current Year
(optional)
1 Aggregate fair market value of all non-exempt-use assets (see instructions for short tax year or assets held for part of year): 1
a Average monthly value of securities 1a    
b Average monthly cash balances 1b    
c Fair market value of other non-exempt-use assets 1c    
d Total (add lines 1a, 1b, and 1c) 1d    
e Discount claimed for blockage or other factors
(explain in detail in Part VI):  
2 Acquisition indebtedness applicable to non-exempt use assets 2    
3 Subtract line 2 from line 1d 3    
4 Cash deemed held for exempt use. Enter 0.015 of line 3 (for greater amount, see instructions). 4    
5 Net value of non-exempt-use assets (subtract line 4 from line 3) 5    
6 Multiply line 5 by 0.035 6    
7 Recoveries of prior-year distributions 7    
8 Minimum Asset Amount (add line 7 to line 6) 8    
Section C - Distributable Amount Current Year
1 Adjusted net income for prior year (from Section A, line 8, Column A) 1  
2 Enter 85% of line 1 2  
3 Minimum asset amount for prior year (from Section B, line 8, Column A) 3  
4 Enter greater of line 2 or line 3 4  
5 Income tax imposed in prior year 5  
6 Distributable Amount. Subtract line 5 from line 4, unless subject to emergency temporary reduction (see instructions) 6  
7
Schedule A (Form 990) 2021

Schedule A (Form 990) 2021
Page 7
Part V
Type III Non-Functionally Integrated 509(a)(3) Supporting Organizations(continued)
Section D - Distributions Current Year
1 Amounts paid to supported organizations to accomplish exempt purposes 1  
2 Amounts paid to perform activity that directly furthers exempt purposes of supported organizations, in
excess of income from activity
2  
3 Administrative expenses paid to accomplish exempt purposes of supported organizations 3  
4 Amounts paid to acquire exempt-use assets 4  
5 Qualified set-aside amounts (prior IRS approval required - provide details in Part VI) 5  
6 Other distributions (describe in Part VI). See instructions 6  
7Total annual distributions. Add lines 1 through 6. 7  
8 Distributions to attentive supported organizations to which the organization is responsive (provide
details in Part VI
). See instructions
8  
9 Distributable amount for 2021 from Section C, line 6 9  
10 Line 8 amount divided by Line 9 amount 10  
Section E - Distribution Allocations (see instructions) (i)
Excess Distributions
(ii)
Underdistributions
Pre-2021
(iii)
Distributable
Amount for 2021
1 Distributable amount for 2021 from Section C, line 6  
2 Underdistributions, if any, for years prior to 2021 (reasonable cause required-- explain in Part VI).
See instructions.
 
3 Excess distributions carryover, if any, to 2021:
a From 2016.......  
b From 2017.......  
c From 2018.......  
d From 2019.......  
e From 2020.......  
fTotal of lines 3a through e  
g Applied to underdistributions of prior years  
h Applied to 2021 distributable amount  
i Carryover from 2016 not applied (see
instructions)
 
j Remainder. Subtract lines 3g, 3h, and 3i from line 3f.  
4Distributions for 2021 from Section D, line 7:
$  
a Applied to underdistributions of prior years  
b Applied to 2021 distributable amount  
c Remainder. Subtract lines 4a and 4b from line 4.  
5 Remaining underdistributions for years prior to
2021, if any. Subtract lines 3g and 4a from line 2.
If the amount is greater than zero, explain in Part VI.
See instructions.
 
6 Remaining underdistributions for 2021. Subtract
lines 3h and 4b from line 1. If the amount is greater
than zero, explain in Part VI. See instructions.
 
7 Excess distributions carryover to 2022. Add lines
3j and 4c.
 
8 Breakdown of line 7:
a Excess from 2017.....  
b Excess from 2018.....  
c Excess from 2019.....  
d Excess from 2020.....  
e Excess from 2021.....  
Schedule A (Form 990) (2021)

Schedule A (Form 990) 2021
Page 8
Part VI
Supplemental Information. Provide the explanations required by Part II, line 10; Part II, line 17a or 17b; Part III, line 12; Part IV, Section A, lines 1, 2, 3b, 3c, 4b, 4c, 5a, 6, 9a, 9b, 9c, 11a, 11b, and 11c; Part IV, Section B, lines 1 and 2; Part IV, Section C, line 1; Part IV, Section D, lines 2 and 3; Part IV, Section E, lines 1c, 2a, 2b, 3a and 3b; Part V, line 1; Part V, Section B, line 1e; Part V Section D, lines 5, 6, and 8; and Part V, Section E, lines 2, 5, and 6. Also complete this part for any additional information. (See instructions).
Facts And Circumstances Test
 
Return Reference Explanation
Schedule A (Form 990) 2021


Additional Data


Software ID: 21014044
Software Version: 2021v4.2
Schedule B
(Form 990)
Department of the Treasury
Internal Revenue Service
Schedule of Contributors

Arrow Bullet Attach to Form 990, 990-EZ, or 990-PF.
Arrow Bullet Go to www.irs.gov/Form990 for the latest information.
OMB No. 1545-0047
2021
Name of the organization
Howard Hughes Medical Institute
 
Employer identification number

59-0735717
Organization type (check one):
Filers of:
Section:
Form 990 or 990-EZ






Form 990-PF




Check if your organization is covered by the General Rule or a Special Rule.  
Note: Only a section 501(c)(7), (8), or (10) organization can check boxes for both the General Rule and a Special Rule. See instructions.
General Rule
Special Rules
......... Arrow Bullet $  
Caution: An organization that isn't covered by the General Rule and/or the Special Rules doesn't file Schedule B (Form 990,
990-EZ, or 990-PF), but it must answer “No” on Part IV, line 2, of its Form 990; or check the box on line H of its Form 990-EZ
or on its Form 990PF, Part I, line 2, to certify that it doesn't meet the filing requirements of Schedule B (Form 990,
990-EZ, or 990-PF).
For Paperwork Reduction Act Notice, see the Instructions
for Form 990, 990-EZ, or 990-PF.
Cat. No. 30613XSchedule B (Form 990) (2021)
Schedule B (Form 990) (2021) Page 2
Name of organization
Howard Hughes Medical Institute
 
Employer identification number
59-0735717
Part I
Contributors
Contributors (see instructions). Use duplicate copies of Part I if additional space is needed.
(a)
No.
(b)
Name, address, and ZIP + 4
(c)
Total contributions
(d)
Type of contribution
RESTRICTED
 
 
 
 
  ,    

$ RESTRICTED


(Complete Part II for noncash contributions.)
(a)
No.
(b)
Name, address, and ZIP + 4
(c)
Total contributions
(d)
Type of contribution
 
 
 
 

$  


(Complete Part II for noncash contributions.)
(a)
No.
(b)
Name, address, and ZIP + 4
(c)
Total contributions
(d)
Type of contribution
 
 
 
 

$  


(Complete Part II for noncash contributions.)
(a)
No.
(b)
Name, address, and ZIP + 4
(c)
Total contributions
(d)
Type of contribution
 
 
 
 

$  


(Complete Part II for noncash contributions.)
(a)
No.
(b)
Name, address, and ZIP + 4
(c)
Total contributions
(d)
Type of contribution
 
 
 
 

$  


(Complete Part II for noncash contributions.)
(a)
No.
(b)
Name, address, and ZIP + 4
(c)
Total contributions
(d)
Type of contribution
 
 
 
 

$  


(Complete Part II for noncash contributions.)
Schedule B (Form 990) (2021)
Schedule B (Form 990) (2021)
Page 3
Name of organization
Howard Hughes Medical Institute
 
Employer identification number

59-0735717
Part II
Noncash Property (see instructions). Use duplicate copies of Part II if additional space is needed.
(a)
No. from Part I
(b)
Description of noncash property given
(c)
FMV (or estimate)
(See instructions)
(d)
Date received
 
$    
(a)
No. from Part I
(b)
Description of noncash property given
(c)
FMV (or estimate)
(See instructions)
(d)
Date received
 
$    
(a)
No. from Part I
(b)
Description of noncash property given
(c)
FMV (or estimate)
(See instructions)
(d)
Date received
 
$    
(a)
No. from Part I
(b)
Description of noncash property given
(c)
FMV (or estimate)
(See instructions)
(d)
Date received
 
$    
(a)
No. from Part I
(b)
Description of noncash property given
(c)
FMV (or estimate)
(See instructions)
(d)
Date received
 
$    
(a)
No. from Part I
(b)
Description of noncash property given
(c)
FMV (or estimate)
(See instructions)
(d)
Date received
 
$    
Schedule B (Form 990) (2021)
Schedule B (Form 990) (2021)
Page 4
Name of organization
Howard Hughes Medical Institute
 
Employer identification number

59-0735717
Part III
Exclusively religious, charitable, etc., contributions to organizations described in section 501(c)(7), (8), or (10) that total more than $1,000 for the year from any one contributor. Complete columns (a) through (e) and the following line entry. For organizations completing Part III, enter the total of exclusively religious, charitable, etc., contributions of $1,000 or less for the year. (Enter this information once. See instructions.) Arrow Bullet$  
Use duplicate copies of Part III if additional space is needed.
(a)
No. from Part I
(b) Purpose of gift (c) Use of gift (d) Description of how gift is held
 
(e) Transfer of gift
Transferee's name, address, and ZIP 4 Relationship of transferor to transferee
 
 
     
 
(a)
No. from Part I
(b) Purpose of gift (c) Use of gift (d) Description of how gift is held
 
(e) Transfer of gift
Transferee's name, address, and ZIP 4 Relationship of transferor to transferee
 
 
     
 
(a)
No. from Part I
(b) Purpose of gift (c) Use of gift (d) Description of how gift is held
 
(e) Transfer of gift
Transferee's name, address, and ZIP 4 Relationship of transferor to transferee
 
 
     
 
(a)
No. from Part I
(b) Purpose of gift (c) Use of gift (d) Description of how gift is held
 
(e) Transfer of gift
Transferee's name, address, and ZIP 4 Relationship of transferor to transferee
 
 
     
 
Schedule B (Form 990) (2021)
Additional Data


Software ID: 21014044
Software Version: 2021v4.2
SCHEDULE C
(Form 990)

Department of the Treasury
Internal Revenue Service
Political Campaign and Lobbying Activities

For Organizations Exempt From Income Tax Under section 501(c) and section 527

SchCMd Bullet Complete if the organization is described below. SchCMd Bullet Attach to Form 990 or Form 990-EZ.
SchCMd BulletGo to www.irs.gov/Form990 for instructions and the latest information.
OMB No. 1545-0047
2021
Open to Public
Inspection
If the organization answered "Yes" on Form 990, Part IV, Line 3, or Form 990-EZ, Part V, line 46 (Political Campaign Activities), then
Round Bullet Section 501(c)(3) organizations: Complete Parts I-A and B. Do not complete Part I-C.
Round Bullet Section 501(c) (other than section 501(c)(3)) organizations: Complete Parts I-A and C below. Do not complete Part I-B.
Round Bullet Section 527 organizations: Complete Part I-A only.
If the organization answered "Yes" on Form 990, Part IV, Line 4, or Form 990-EZ, Part VI, line 47 (Lobbying Activities), then
Round Bullet Section 501(c)(3) organizations that have filed Form 5768 (election under section 501(h)): Complete Part II-A. Do not complete Part II-B.
Round Bullet Section 501(c)(3) organizations that have NOT filed Form 5768 (election under section 501(h)): Complete Part II-B. Do not complete Part II-A.
If the organization answered "Yes" on Form 990, Part IV, Line 5 (Proxy Tax) (see separate instructions) or Form 990-EZ, Part V, line 35c (Proxy Tax) (see separate instructions), then
Round Bullet Section 501(c)(4), (5), or (6) organizations: Complete Part III.
Name of the organization
Howard Hughes Medical Institute
 
Employer identification number

59-0735717
Part I-A
Complete if the organization is exempt under section 501(c) or is a section 527 organization.

1
Provide a description of the organization’s direct and indirect political campaign activities in Part IV. See instructions for definition of “political campaign activities."

2
Political campaign activity expenditures. See instructions ....................................................................SchCMd Bullet
$  
3
Volunteer hours for political campaign activities. See instructions ..................................................................
 

Part I-B
Complete if the organization is exempt under section 501(c)(3).
1
Enter the amount of any excise tax incurred by the organization under section 4955 ................................SchCMd Bullet
$  
2
Enter the amount of any excise tax incurred by organization managers under section 4955 .......................SchCMd Bullet
$  
3
If the organization incurred a section 4955 tax, did it file Form 4720 for this year? .........................................
4a
Was a correction made? ......................................................................................................................
b
If "Yes," describe in Part IV.
Part I-C
Complete if the organization is exempt under section 501(c), except section 501(c)(3).
1
Enter the amount directly expended by the filing organization for section 527 exempt function activities ..... SchCMd Bullet
$  
2
Enter the amount of the filing organization's funds contributed to other organizations for section 527 exempt function activities ............................................................................................................................SchCMd Bullet

$  
3
Total exempt function expenditures. Add lines 1 and 2. Enter here and on Form 1120-POL, line 17b...........SchCMd Bullet

$  
4
Did the filing organization file Form 1120-POL for this year? ...................................................................
5
Enter the names, addresses and employer identification number (EIN) of all section 527 political organizations to which the filing
organization made payments. For each organization listed, enter the amount paid from the filing organization’s funds. Also enter the amount of political contributions received that were promptly and directly delivered to a separate political organization, such as a separate segregated fund or a political action committee (PAC). If additional space is needed, provide information in Part IV.
(a) Name (b) Address (c) EIN (d) Amount paid from filing organization's funds. If none, enter -0-. (e) Amount of political contributions received and promptly and directly delivered to a separate political organization. If none, enter -0-.
1
2
3
4
5
6
For Paperwork Reduction Act Notice, see the instructions for Form 990.
Cat. No. 50084S
Schedule C (Form 990) 2021

Schedule C (Form 990) 2021
Page 2
Part II-A
Complete if the organization is exempt under section 501(c)(3) and filed Form 5768 (election under section 501(h)).
A Check SchCMd Bulletexpenses, and share of excess lobbying expenditures).
B Check SchCMd Bullet
Limits on Lobbying Expenditures
(The term "expenditures" means amounts paid or incurred.)
(a) Filing
organization's
totals
(b) Affiliated group totals
1a Total lobbying expenditures to influence public opinion (grass roots lobbying) ......................    
b Total lobbying expenditures to influence a legislative body (direct lobbying) ........................    
c Total lobbying expenditures (add lines 1a and 1b) ............................................................    
d Other exempt purpose expenditures ...............................................................................    
e Total exempt purpose expenditures (add lines 1c and 1d) ..................................................    
f Lobbying nontaxable amount. Enter the amount from the following table in both
columns.
   
If the amount on line 1e, column (a) or (b) is:The lobbying nontaxable amount is:
Not over $500,00020% of the amount on line 1e.
Over $500,000 but not over $1,000,000$100,000 plus 15% of the excess over $500,000.
Over $1,000,000 but not over $1,500,000$175,000 plus 10% of the excess over $1,000,000.
Over $1,500,000 but not over $17,000,000$225,000 plus 5% of the excess over $1,500,000.
Over $17,000,000$1,000,000.
g Grassroots nontaxable amount (enter 25% of line 1f) .................................................    
h Subtract line 1g from line 1a. If zero or less, enter -0-. ................................................    
i Subtract line 1f from line 1c. If zero or less, enter -0-. ................................................    
j If there is an amount other than zero on either line 1h or line 1i, did the organization file Form 4720 reporting
section 4911 tax for this year? ...................................................................................................................

4-Year Averaging Period Under Section 501(h)
(Some organizations that made a section 501(h) election do not have to complete all of the five
columns below. See the separate instructions for lines 2a through 2f.)
Lobbying Expenditures During 4-Year Averaging Period
Calendar year (or fiscal year
beginning in)
(a) 2018 (b) 2019 (c) 2020 (d) 2021 (e) Total
2a Lobbying nontaxable amount          
b Lobbying ceiling amount
(150% of line 2a, column(e))
 
c Total lobbying expenditures          
d Grassroots nontaxable amount          
e Grassroots ceiling amount
(150% of line 2d, column (e))
 
f Grassroots lobbying expenditures          
Schedule C (Form 990) 2021


Schedule C (Form 990) 2021
Page 3
Part II-B
Complete if the organization is exempt under section 501(c)(3) and has NOT filed Form 5768 (election under section 501(h)).
For each "Yes" response on lines 1a through 1i below, provide in Part IV a detailed description of the lobbying activity.
(a)
Yes|No
(b)
Amount
1
During the year, did the filing organization attempt to influence foreign, national, state or local legislation, including any attempt to influence public opinion on a legislative matter or referendum, through the use of:
a
Volunteers? ...........................................................................................................
 
No
b
Paid staff or management (include compensation in expenses reported on lines 1c through 1i)? ........
 
No
c
Media advertisements? ...................................................................................................
 
No
 
d
Mailings to members, legislators, or the public? .............................................................................
 
No
 
e
Publications, or published or broadcast statements? ...........................................................
 
No
 
f
Grants to other organizations for lobbying purposes? ..........................................................
 
No
 
g
Direct contact with legislators, their staffs, government officials, or a legislative body? .......................
Yes
 
112,500
h
Rallies, demonstrations, seminars, conventions, speeches, lectures, or any similar means? ..................
 
No
 
i
Other activities? ...................................................................................................................
Yes
 
8,012
j
Total. Add lines 1c through 1i ....................................................................................................
120,512
2a
Did the activities in line 1 cause the organization to be not described in section 501(c)(3)? .....
 
No
b
If "Yes," enter the amount of any tax incurred under section 4912 ...........................................
 
c
If "Yes," enter the amount of any tax incurred by organization managers under section 4912 ...................
 
d
If the filing organization incurred a section 4912 tax, did it file Form 4720 for this year? ........................
 
 
Part III-A
Complete if the organization is exempt under section 501(c)(4), section 501(c)(5), or section 501(c)(6).
Yes
No
1
Were substantially all (90% or more) dues received nondeductible by members? ...............................................
1
 
 
2
Did the organization make only in-house lobbying expenditures of $2,000 or less? ............................................
2
 
 
3
Did the organization agree to carry over lobbying and political expenditures from the prior year? .................................
3
 
 
Part III-B
Complete if the organization is exempt under section 501(c)(4), section 501(c)(5), or section 501(c)(6) and if either (a) BOTH Part III-A, lines 1 and 2, are answered "No" OR (b) Part III-A, line 3, is answered “Yes."
1
Dues, assessments and similar amounts from members ......................................................................
1
 
2
Section 162(e) nondeductible lobbying and political expenditures (do not include amounts of political expenses for which the section 527(f) tax was paid).
a
Current year .............................................................................................................................
2a
 
b
Carryover from last year ............................................................................................................
2b
 
c
Total ...........................................................................................................................................
2c
 
3
Aggregate amount reported in section 6033(e)(1)(A) notices of nondeductible section 162(e) dues .
3
 
4
If notices were sent and the amount on line 2c exceeds the amount on line 3, what portion of the excess does the organization agree to carryover to the reasonable estimate of nondeductible lobbying and political expenditure next year? ......................................................................................................................
4
 
5
Taxable amount of lobbying and political expenditures. See Instructions .........................................
5
 
Part IV
Supplemental Information
Provide the descriptions required for Part l-A, line 1; Part l-B, line 4; Part l-C, line 5; Part II-A (affiliated group list); Part II-A, lines 1 and 2 (see instructions), and Part ll-B, line 1. Also, complete this part for any additional information.
Return Reference Explanation
Schedule C, Part II-B, Line 1 DETAILED DESCRIPTION OF THE LOBBYING ACTIVITY SCHEDULE C, PART II-B, LINE 1g (DIRECT CONTACT) AMOUNTS PAID TO LOBBYING FIRM FOR DIRECT CONTACT WITH FEDERAL AND STATE LEGISLATORS AND THEIR STAFFS ON PENDING LEGISLATIVE MATTERS. SCHEDULE C, PART II-B, LINE 1i (OTHER ACTIVITIES) DURING THE FISCAL YEAR, HHMI WAS A MEMBER OF A NUMBER OF NON-PROFIT ORGANIZATIONS THAT ENGAGED IN LOBBYING ACTIVITIES ON BEHALF OF THEIR MEMBERSHIPS. HHMI IS REPORTING AS LOBBYING EXPENDITURES A PORTION OF THE MEMBERSHIP DUES THAT HHMI PAID TO THESE ORGANIZATIONS.
Schedule C (Form 990) 2021


Additional Data


Software ID: 21014044
Software Version: 2021v4.2

SCHEDULE D
(Form 990)
Department of the Treasury
Internal Revenue Service
Supplemental Financial Statements
SchDMd Bullet Complete if the organization answered "Yes," on Form 990,
Part IV, line 6, 7, 8, 9, 10, 11a, 11b, 11c, 11d, 11e, 11f, 12a, or 12b.
SchDMd Bullet Attach to Form 990.
SchDMd Bullet Go to www.irs.gov/Form990 for instructions and the latest information.
OMB No. 1545-0047
2021
Open to Public Inspection
Name of the organization
Howard Hughes Medical Institute
 
Employer identification number

59-0735717
Part I
Organizations Maintaining Donor Advised Funds or Other Similar Funds or Accounts. Complete if the organization answered "Yes" on Form 990, Part IV, line 6.
(a) Donor advised funds (b) Funds and other accounts
1 Total number at end of year .........    
2 Aggregate value of contributions to (during year)    
3 Aggregate value of grants from (during year)    
4 Aggregate value at end of year ........    
5
Did the organization inform all donors and donor advisors in writing that the assets held in donor advised funds are the organization’s property, subject to the organization’s exclusive legal control? ............
6
Did the organization inform all grantees, donors, and donor advisors in writing that grant funds can be used only for charitable purposes and not for the benefit of the donor or donor advisor, or for any other purpose conferring impermissible private benefit? ...................................
Part II
Conservation Easements.
Complete if the organization answered "Yes" on Form 990, Part IV, line 7.
1
Purpose(s) of conservation easements held by the organization (check all that apply).
2
Complete lines 2a through 2d if the organization held a qualified conservation contribution in the form of a conservation easement on the last day of the tax year.
Held at the End of the Year
a Total number of conservation easements ...................... 2a  
b Total acreage restricted by conservation easements .................... 2b  
c Number of conservation easements on a certified historic structure included in (a) ..... 2c  
d Number of conservation easements included in (c) acquired after 7/25/06, and not on a historic structure listed in the National Register ... 2d  
3
Number of conservation easements modified, transferred, released, extinguished, or terminated by the organization during the
tax year SchDMd Bullet  
4
Number of states where property subject to conservation easement is located SchDMd Bullet  
5
Does the organization have a written policy regarding the periodic monitoring, inspection, handling of violations, and enforcement of the conservation easements it holds? ............
6
Staff and volunteer hours devoted to monitoring, inspecting, handling of violations, and enforcing conservation easements during the year
SchDMd Bullet  
7
Amount of expenses incurred in monitoring, inspecting, handling of violations, and enforcing conservation easements during the year
SchDMd Bullet $  
8
Does each conservation easement reported on line 2(d) above satisfy the requirements of section 170(h)(4)(B)(i) and section 170(h)(4)(B)(ii)? .............................
9
In Part XIII, describe how the organization reports conservation easements in its revenue and expense statement, and
balance sheet, and include, if applicable, the text of the footnote to the organization’s financial statements that describes
the organization’s accounting for conservation easements.
Part III
Organizations Maintaining Collections of Art, Historical Treasures, or Other Similar Assets.
Complete if the organization answered "Yes" on Form 990, Part IV, line 8.
1a
If the organization elected, as permitted under FASB ASC 958, not to report in its revenue statement and balance sheet works of art, historical treasures, or other similar assets held for public exhibition, education, or research in furtherance of public service, provide, in Part XIII, the text of the footnote to its financial statements that describes these items.
b
If the organization elected, as permitted under FASB ASC 958, to report in its revenue statement and balance sheet works of art, historical treasures, or other similar assets held for public exhibition, education, or research in furtherance of public service, provide the following amounts relating to these items:
(i)
Revenue included on Form 990, Part VIII, line 1 .........................SchDMd Bullet $  
(ii)
Assets included in Form 990, Part X ...............................SchDMd Bullet $  
2
If the organization received or held works of art, historical treasures, or other similar assets for financial gain, provide the
following amounts required to be reported under FASB ASC 958 relating to these items:
a
Revenue included on Form 990, Part VIII, line 1 ..........................SchDMd Bullet $  
b
Assets included in Form 990, Part X ...............................SchDMd Bullet $  
For Paperwork Reduction Act Notice, see the Instructions for Form 990.
Cat. No. 52283D
Schedule D (Form 990) 2021

Schedule D (Form 990) 2021
Page 2
Part III
Organizations Maintaining Collections of Art, Historical Treasures, or Other Similar Assets (continued)
3
Using the organization’s acquisition, accession, and other records, check any of the following that are a significant use of its collection items (check all that apply):
a
d
b
e
 
c
4
Provide a description of the organization’s collections and explain how they further the organization’s exempt purpose in
Part XIII.
5
During the year, did the organization solicit or receive donations of art, historical treasures or other similar
assets to be sold to raise funds rather than to be maintained as part of the organization’s collection?...
Part IV
Escrow and Custodial Arrangements. Complete if the organization answered "Yes" on Form 990, Part IV, line 9, or reported an amount on Form 990, Part X, line 21.
1a
Is the organization an agent, trustee, custodian or other intermediary for contributions or other assets not
included on Form 990, Part X? ....................................
b If "Yes," explain the arrangement in Part XIII and complete the following table: Amount
c Beginning balance ............................. 1c  
d Additions during the year ............................ 1d  
e Distributions during the year .......................... 1e  
f Ending balance ................................ 1f  
2a
Did the organization include an amount on Form 990, Part X, line 21, for escrow or custodial account liability? ...
b
If "Yes," explain the arrangement in Part XIII. Check here if the explanation has been provided in Part XIII ....
Part V
Endowment Funds.
Complete if the organization answered "Yes" on Form 990, Part IV, line 10.
(a) Current year (b) Prior year (c) Two years back (d) Three years back (e) Four years back
1a Beginning of year balance ....          
b Contributions ...          
c Net investment earnings, gains, and losses          
d Grants or scholarships ...          
e Other expenditures for facilities
and programs ...
         
f Administrative expenses ....          
g End of year balance ......          
2
Provide the estimated percentage of the current year end balance (line 1g, column (a)) held as:
a
Board designated or quasi-endowment SchDMd Bullet  
b
Permanent endowment SchDMd Bullet  
c
Term endowment SchDMd Bullet  
The percentages on lines 2a, 2b, and 2c should equal 100%.
3a
Are there endowment funds not in the possession of the organization that are held and administered for the
organization by:

Yes
No
(i) Unrelated organizations .................
3a(i)
 
 
(ii) Related organizations .................
3a(ii)
 
 
b
If "Yes" on 3a(ii), are the related organizations listed as required on Schedule R? .........
3b
 
 
4
Describe in Part XIII the intended uses of the organization's endowment funds.
Part VI
Land, Buildings, and Equipment.
Complete if the organization answered "Yes" on Form 990, Part IV, line 11a. See Form 990, Part X, line 10.
Description of property (a) Cost or other basis
(investment)
(b) Cost or other basis (other) (c) Accumulated depreciation (d) Book value
1a Land ..... 807,737 96,884,682 97,692,419
b Buildings .... 10,248,413 857,362,804 434,277,066 433,334,151
c Leasehold improvements   347,137,748 336,548,744 10,589,004
d Equipment ....   750,523,024 514,580,572 235,942,452
e Other ..... 921,448 62,190,486   63,111,934
Total. Add lines 1a through 1e. (Column (d) must equal Form 990, Part X, column (B), line 10(c).)..SchDMdBullet 840,669,960
Schedule D (Form 990) 2021

Schedule D (Form 990) 2021
Page 3
Part VII
Investments - Other Securities.
Complete if the organization answered "Yes" on Form 990, Part IV, line 11b. See Form 990, Part X, line 12.
(a) Description of security or category
(including name of security)
(b) Book value (c) Method of valuation:
Cost or end-of-year market value
(1) Financial derivatives.........    
(2) Closely-held equity interests........    
(3) Other
(A) PRIVATE EQUITY
6,899,709,829 F

(B) REAL ASSETS
1,905,467,831 F

(C) PUBLIC EQUITY
5,293,449,413 F

(D) INDEPENDENT RETURN
4,795,158,481 F

(E) DISTRESSED & CREDIT SENSITIVE
   

(F) HEDGED EQUITY
   

(G) MARKET NEUTRAL
   
(G)
(H)
Total. (Column (b) must equal Form 990, Part X, col. (B) line 12.)Small Bullet 18,893,785,554
Part VIII
Investments - Program Related. Complete if the organization answered 'Yes' on Form 990, Part IV, line 11c. See Form 990, Part X, line 13.
(a) Description of investment (b) Book value (c) Method of valuation:
Cost or end-of-year market value
(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
Total. (Column (b) must equal Form 990, Part X, col.(B) line 13.)Small Bullet  
Part IX
Other Assets.
Complete if the organization answered 'Yes' on Form 990, Part IV, line 11d. See Form 990, Part X, line 15.
(a) Description (b) Book value
(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
Total. (Column (b) must equal Form 990, Part X, col.(B) line 15.)...........Small Bullet  
Part X
Other Liabilities.
Complete if the organization answered 'Yes' on Form 990, Part IV, line 11e or 11f. See Form 990, Part X, line 25.
1.(a) Description of liability (b) Book value
(1) Federal income taxes  
(8)
(9)
Total. (Column (b) must equal Form 990, Part X, col.(B) line 25.)Small Bullet 730,014,837
2. Liability for uncertain tax positions. In Part XIII, provide the text of the footnote to the organization's financial statements that reports the organization's liability for uncertain tax positions under FIN 48 (ASC 740). Check here if the text of the footnote has been provided in Part XIII
Schedule D (Form 990) 2021

Schedule D (Form 990) 2021
Page 4
Part XI Reconciliation of Revenue per Audited Financial Statements With Revenue per Return. Complete if the organization answered 'Yes' on Form 990, Part IV, line 12a.
1 Total revenue, gains, and other support per audited financial statements ....... 1  
2 Amounts included on line 1 but not on Form 990, Part VIII, line 12:
a Net unrealized gains (losses) on investments .... 2a  
b Donated services and use of facilities ......... 2b  
c Recoveries of prior year grants ........... 2c  
d Other (Describe in Part XIII.) ............ 2d  
e Add lines 2a through 2d ..................... 2e  
3 Subtract line 2e from line 1.................. 3  
4 Amounts included on Form 990, Part VIII, line 12, but not on line 1:
a Investment expenses not included on Form 990, Part VIII, line 7b . 4a  
b Other (Describe in Part XIII.) ........... 4b  
c Add lines 4a and 4b.................... 4c  
5 Total revenue. Add lines 3 and 4c. (This must equal Form 990, Part I, line 12.) ...... 5  
Part XII Reconciliation of Expenses per Audited Financial Statements With Expenses per Return. Complete if the organization answered 'Yes' on Form 990, Part IV, line 12a.
1 Total expenses and losses per audited financial statements ........... 1  
2 Amounts included on line 1 but not on Form 990, Part IX, line 25:
a Donated services and use of facilities ......... 2a  
b Prior year adjustments ............ 2b  
c Other losses ................ 2c  
d Other (Describe in Part XIII.) ............ 2d  
e Add lines 2a through 2d.................... 2e  
3 Subtract line 2e from line 1................... 3  
4 Amounts included on Form 990, Part IX, line 25, but not on line 1:
a Investment expenses not included on Form 990, Part VIII, line 7b .. 4a  
b Other (Describe in Part XIII.) ............ 4b  
c Add lines 4a and 4b..................... 4c  
5 Total expenses. Add lines 3 and 4c. (This must equal Form 990, Part I, line 18.) ...... 5  
Part XIII
Supplemental Information
Provide the descriptions required for Part II, lines 3, 5, and 9; Part III, lines 1a and 4; Part lV, lines 1b and 2b; Part V, line 4; Part X, line 2; Part XI, lines 2d and 4b; and Part XII, lines 2d and 4b. Also complete this part to provide any additional information.
Return Reference Explanation
Schedule D, Part X, Line 2 FIN 48 (ASC 740) footnote In accordance with the guidance on accounting for uncertainty in income taxes, management regularly evaluates its tax positions and does not believe the Institute has any uncertain tax positions that result in a material impact on the Institute's consolidated financial position or change in total net assets. The Institute is subject to routine audits by taxing jurisdictions. The Institute believes it is no longer subject to income tax examinations for fiscal years prior to the year ended August 31, 2018.
Schedule D (Form 990) 2021


Additional Data


Software ID: 21014044
Software Version: 2021v4.2




SCHEDULE F(Form 990)
Department of the Treasury
Internal Revenue Service
Statement of Activities Outside the United States
Right pointing arrow large image Complete if the organization answered "Yes" to Form 990, Part IV, line 14b, 15, or 16.Right pointing arrow large image Attach to Form 990.Right pointing arrow large image Go to www.irs.gov/Form990 for instructions and the latest information.
OMB No. 1545-0047
2021
Open to Public Inspection
Name of the organization
Howard Hughes Medical Institute
 
Employer identification number

59-0735717
Part I
General Information on Activities Outside the United States. Complete if the organization answered "Yes" on Form 990, Part IV, line 14b.
1
For grantmakers. Does the organization maintain records to substantiate the amount of its grants and
other assistance, the grantees’ eligibility for the grants or assistance, and the selection criteria used
to award the grants or assistance? . . . . . . . . . . . . . . . . . . . . . . . . .
2
For grantmakers. Describe in Part V the organization’s procedures for monitoring the use of its grants and other assistance outside the United States.
3
Activites per Region. (The following Part I, line 3 table can be duplicated if additional space is needed.)
(a) Region (b) Number of offices in the region (c) Number of employees, agents, and independent contractors in the region (d) Activities conducted in region (by type) (such as, fundraising, program services, investments, grants to recipients located in the region) (e) If activity listed in (d) is a program service, describe specific type of
service(s) in the region
(f) Total expenditures
for and investments
in the region
Central America and the Caribbean     Investments   7,556,893,597
North America (Canada & Mexico only)     Investments   310,745,307
Europe (Including Iceland and Greenland)     Investments   1,705,845,468
South Asia     Investments   211,738
Sub-Saharan Africa     Investments   7,726,781
Central America and the Caribbean     Investment Management Fees   5,524,857
North America (Canada & Mexico only)     Investment Management Fees   1,997,376
Europe (Including Iceland and Greenland)     Investment Management Fees   17,458,723
Europe (Including Iceland and Greenland)     Grantmaking   201,620
Sub-Saharan Africa     Grantmaking   375,000
Europe (Including Iceland and Greenland)     Program Services Science Ed / e-Life 2,000,291
North America (Canada & Mexico only)   4 Program Services Science Ed / Educational Media 23,383
East Asia and the Pacific   1 Program Services Science Ed / Tangled Bank 395,853
Europe (Including Iceland and Greenland)   23 Program Services Science Ed / Tangled Bank 3,619,145
North America (Canada & Mexico only)   4 Program Services Science Ed / Tangled Bank 370,388
South America   1 Program Services Science Ed / Tangled Bank 6,030
South Asia   3 Program Services Science Ed / Tangled Bank 246,284
Sub-Saharan Africa   8 Program Services Science Ed / Tangled Bank 19,544
East Asia and the Pacific     Program Services Medical Research 55,473
Europe (Including Iceland and Greenland)     Program Services Medical Research 532,241
Europe (Including Iceland and Greenland)     Program Services Science Ed / Educational Media 13,951
Central America and the Caribbean     Program Services Medical Research 945
North America (Canada & Mexico only)     Program Services Medical Research 27,546
Europe (Including Iceland and Greenland)     Program Services Science Ed 1,512
Middle East and North Africa     Program Services Medical Research 13,118
South America     Program Services Medical Research 17,890
3a Sub-total .... 0 33 9,613,395,557
b Total from continuation sheets to Part I ... 0 11 928,504
c Totals (add lines 3a and 3b) 0 44 9,614,324,061
For Paperwork Reduction Act Notice, see the Instructions for Form 990.Cat. No. 50082W Schedule F (Form 990) 2021
Schedule F (Form 990) 2021
Page 2
Part II
Grants and Other Assistance to Organizations or Entities Outside the United States. Complete if the organization answered "Yes" on Form 990, Part IV, line 15, for any recipient who received more than $5,000. Part II can be duplicated if additional space is needed.
1 (a) Name of organization (b) IRS code section
and EIN (if applicable)
(c) Region (d) Purpose of
grant
(e) Amount of
cash grant
(f) Manner of
cash
disbursement
(g) Amount
of noncash
assistance
(h) Description
of noncash
assistance
(i) Method of
valuation
(book, FMV,
appraisal, other)
Europe (Including Iceland and Greenland) Open Access 201,620 WIRE      
Sub-Saharan Africa Science Education 375,000 WIRE      
             
             
             
             
             
             
             
             
             
             
             
             
             
             
2 Enter total number of recipient organizations listed above that are recognized as charities by the foreign country, recognized as tax-exempt by the IRS, or for which the grantee or counsel has provided a section 501(c)(3) equivalency letter .......MediumBullet
2
3 Enter total number of other organizations or entities .......................MediumBullet
0
Schedule F (Form 990) 2021
Schedule F (Form 990) 2021Page 3
Part III
Grants and Other Assistance to Individuals Outside the United States. Complete if the organization answered "Yes" on Form 990, Part IV, line 16.
Part III can be duplicated if additional space is needed.
(a) Type of grant or assistance (b) Region (c) Number of recipients (d) Amount of
cash grant
(e) Manner of cash
disbursement
(f) Amount of
noncash
assistance
(g) Description
of noncash
assistance
(h) Method of
valuation
(book, FMV,
appraisal, other)
               
               
               
               
               
               
               
               
               
               
               
               
               
               
               
               
               
               
Schedule F (Form 990) 2021
Schedule F (Form 990) 2021
Page 4
Part IV
Foreign Forms
1 Was the organization a U.S. transferor of property to a foreign corporation during the tax year? If "Yes," the organization may be required to file Form 926, Return by a U.S. Transferor of Property to a Foreign Corporation (see Instructions for Form 926). . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
2 Did the organization have an interest in a foreign trust during the tax year? If "Yes," the organization may be required to separately file Form 3520, Annual Return to Report Transactions with Foreign Trusts and Receipt of Certain Foreign Gifts, and/or Form 3520-A, Annual Information Return of Foreign Trust With a U.S. Owner (see Instructions for Forms 3520 and 3520-A; don't file with Form 990). . . . . . . . . . . . . . . . . . . . . . . .
3 Did the organization have an ownership interest in a foreign corporation during the tax year? If "Yes," the organization may be required to file Form 5471, Information Return of U.S. Persons with Respect to Certain Foreign Corporations. (see Instructions for Form 5471). . . . . . . . . . . . . . . . . . . . . . . . . . . .
4 Was the organization a direct or indirect shareholder of a passive foreign investment company or a qualified electing fund during the tax year? If “Yes,” the organization may be required to file Form 8621, Information Return by a Shareholder of a Passive Foreign Investment Company or Qualified Electing Fund. (see Instructions for Form 8621) .
5 Did the organization have an ownership interest in a foreign partnership during the tax year? If "Yes," the organization may be required to file Form 8865, Return of U.S. Persons with Respect to Certain Foreign Partnerships (see Instructions for Form 8865). . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
6 Did the organization have any operations in or related to any boycotting countries during the tax year? If "Yes," the organization may be required to separately file Form 5713, International Boycott Report (see Instructions for Form 5713; don't file with Form 990).. . . . . . . . . . . . . . . . . . . . . . . . . . . .
Schedule F (Form 990) 2021
Schedule F (Form 990) 2021
Page 5
Part V
Supplemental Information
Provide the information required by Part I, line 2 (monitoring of funds); Part I, line 3, column (f) (accounting method; amounts of investments vs. expenditures per region); Part II, line 1 (accounting method); Part III (accounting method); and Part III, column (c) (estimated number of recipients), as applicable. Also complete this part to provide any additional information. See instructions.
ReturnReference Explanation
Schedule F, Part I, Line 2 Procedures for monitoring use of grant funds DURING ITS 2022 FISCAL YEAR, HHMI CONTINUED TO SUPPORT INTERNATIONAL RESEARCH SCHOLARS SELECTED THROUGH ONE OR MORE COMPETITIONS OPEN TO ALL ELIGIBLE APPLICANTS. THE PROCEDURES DESCRIBED IN THIS SECTION ARE RELATED TO GRANTS THAT WERE ACCRUED IN A PREVIOUS FISCAL YEAR. ELIGIBILITY REQUIREMENTS INCLUDED, BUT WERE NOT LIMITED TO, A FULL-TIME APPOINTMENT AT A NONPROFIT SCIENTIFIC RESEARCH ORGANIZATION IN A COUNTRY OTHER THAN THE UNITED STATES, AND A RESEARCH FOCUS ON BASIC BIOLOGICAL PROCESSES OR DISEASE MECHANISMS. QUALIFIED APPLICANTS WERE EVALUATED BY A PANEL OF SCIENTIFIC EXPERTS WITH FINAL SELECTIONS MADE BY HHMI LEADERSHIP. A SMALL NUMBER OF GRANTS ARE AWARDED BASED ON DIRECT APPLICATION TO HHMI FOR SPECIFIC INITIATIVES DIRECTLY RELATED TO SCIENCE EDUCATION. THE DISBURSEMENT OF GRANT FUNDS TO SUPPORT THE WORK OF INTERNATIONAL EARLY CAREER SCIENTISTS AND SENIOR INTERNATIONAL RESEARCH SCHOLARS IS MADE IN ACCORDANCE WITH ALL APPLICABLE U.S. LAWS. FUNDS ARE PAID TO AN INSTITUTIONAL ACCOUNT. IN ORDER TO MONITOR THE ACTIVITIES AND PRODUCTIVITY OF THE GRANTS, EACH SCIENTIST IS REQUIRED TO SUBMIT AN ANNUAL PROGRESS REPORT CONCERNING HIS OR HER RESEARCH AND EACH GRANTEE INSTITUTION IS REQUIRED TO SUBMIT ANNUAL FINANCIAL REPORTS. THESE REPORTS ARE REVIEWED BY HHMI STAFF. SITE VISITS AND AUDITS ARE CONDUCTED IF WARRANTED AND GRANTEES ATTEND SCIENTIFIC MEETINGS OF HHMI US-BASED SCIENTISTS.
Schedule F, Part I, Line 3 Method used to account for expenditures on org's financial statements CENTRAL AMERICA AND THE CARIBBEAN-Accrual; EAST ASIA AND THE PACIFIC-Accrual; EUROPE (INCLUDING ICELAND AND GREENLAND)-Accrual; MIDDLE EAST AND NORTH AFRICA-Accrual; NORTH AMERICA (CANADA & MEXICO ONLY)-Accrual; SOUTH AMERICA-Accrual; SOUTH ASIA-Accrual; SUB-SAHARAN AFRICA-Accrual
Schedule F, Part II, Line 1 Method used to account for expenditures on org's financial statements EUROPE (INCLUDING ICELAND AND GREENLAND)-Accrual; SUB-SAHARAN AFRICA-Accrual
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
Schedule F (Form 990) 2021
Additional Data


Software ID: 21014044
Software Version: 2021v4.2




Note: To capture the full content of this document, please select landscape mode (11" x 8.5") when printing.

Schedule I
(Form 990)
Department of the Treasury
Internal Revenue Service
Grants and Other Assistance to Organizations,
Governments and Individuals in the United States
Complete if the organization answered "Yes," on Form 990, Part IV, line 21 or 22.
lBullet Attach to Form 990.
lBullet Go to www.irs.gov/Form990 for the latest information.
OMB No. 1545-0047
2021
Open to Public
Inspection
Name of the organization
Howard Hughes Medical Institute
 
Employer identification number
59-0735717
Part I
General Information on Grants and Assistance
1
Does the organization maintain records to substantiate the amount of the grants or assistance, the grantees' eligibility for the grants or assistance, and
the selection criteria used to award the grants or assistance? ........................
2
Describe in Part IV the organization's procedures for monitoring the use of grant funds in the United States.
Part II
Grants and Other Assistance to Domestic Organizations and Domestic Governments. Complete if the organization answered "Yes" on Form 990, Part IV, line 21, for any recipient
that received more than $5,000. Part II can be duplicated if additional space is needed.
(a) Name and address of organization
or government
(b) EIN (c) IRC section
(if applicable)
(d) Amount of cash grant (e) Amount of non-cash
assistance
(f) Method of valuation
(book, FMV, appraisal,
other)
(g) Description of
noncash assistance
(h) Purpose of grant
or assistance
(1) American University
American University
Washington,DC20016
53-0196549 501(c)(3) 10,000       Driving Change Learn. Comm.
(2) Boston University
Boston University
Boston,MA02215
04-2103547 501(c)(3) 10,000       Driving Change Learn. Comm.
(3) Brandeis University
Brandeis University
Waltham,MA02453
04-2103552 501(c)(3) 10,000       Driving Change Learn. Comm.
(4) Brown University
Brown University
Providence,RI029129100
05-0258809 501(c)(3) 10,000       Driving Change Learn. Comm.
(5) Clarkson University
Clarkson University
Potsdam,NY136991401
15-0543659 501(c)(3) 10,000       Driving Change Learn. Comm.
(6) Clemson University
Clemson University
Clemson,SC296345355
57-6000254 South Carolina 10,000       Driving Change Learn. Comm.
(7) Illinois State University
Illinois State University
Normal,IL61761
37-6014070 Illinois 10,000       Driving Change Learn. Comm.
(8) Louisiana State Univ
Louisiana State Univ
Baton Rouge,LA70803
72-6000848 501(c)(3) 10,000       Driving Change Learn. Comm.
(9) Loyola Marymount
Loyola Marymount
Los Angeles,CA90045
95-1643334 501(c)(3) 10,000       Driving Change Learn. Comm.
(10) Ohio State Univ
Ohio State Univ
Columbus,OH432101016
31-6025986 Ohio 10,000       Driving Change Learn. Comm.
(11) Oklahoma State U
Oklahoma State U
Stillwater,OK740781031
73-1383996 Oklahoma 10,000       Driving Change Learn. Comm.
(12) Rice University
Rice University
Houston,TX77005
74-1109620 501(c)(3) 10,000       Driving Change Learn. Comm.
(13) Rutgers University-Camden
Rutgers University-Camden
Camden,NJ08102
22-6001086 501(c)(3) 10,000       Driving Change Learn. Comm.
(14) State University of New York-Albany
State University of New York-Albany
Albany,NY12201
14-1368361 New York 10,000       Driving Change Learn. Comm.
(15) Dartmouth College
Dartmouth College
Hanover,NH03755
02-0222111 501(c)(3) 10,000       Driving Change Learn. Comm.
(16) University of Arizona
University of Arizona
Tucson,AZ85717
74-2652689 Arizona 10,000       Driving Change Learn. Comm.
(17) University of California-Davis
University of California-Davis
Davis,CA95618
94-6036494 California 10,000       Driving Change Learn. Comm.
(18) University of California-Irvine
University of California-Irvine
Irvine,CA92610
95-2226406 California 10,000       Driving Change Learn. Comm.
(19) University of Connecticut
University of Connecticut
Storrs,CT06269
06-0772160 Connecticut 10,000       Driving Change Learn. Comm.
(20) University of Dayton
University of Dayton
Dayton,OH45469
31-0536715 501(c)(3) 10,000       Driving Change Learn. Comm.
(21) University of Illinois at Chicago
University of Illinois at Chicago
Chicago,IL606124305
37-6000511 Illinois 10,000       Driving Change Learn. Comm.
(22) University of Maryland Eastern Shore
University of MD Eastern Shore
Princess Anne,MD21853
52-6002033 Maryland 10,000       Driving Change Learn. Comm.
(23) University of Utah
University of Utah
Salt Lake City,UT84112
87-6000525 UTAH 10,000       Driving Change Learn. Comm.
(24) University of Wisconsin-Milwaukee
University of Wisconsin-Milwaukee
Milwaukee,WI53201
39-1805963 WISCONSIN 10,000       Driving Change Learn. Comm.
(25) Vanderbilt University
Vanderbilt University
Nashville,TN372401591
62-0476822 501(c)(3) 10,000       Driving Change Learn. Comm.
(26) Washington University-St Louis
Washington University-St Louis
St Louis,MO63112
43-0653611 501(c)(3) 10,000       Driving Change Learn. Comm.
(27) Wayne State University
Wayne State University
Detroit,MI48202
38-6028429 501(c)(3) 10,000       Driving Change Learn. Comm.
(28) Massachusetts Institute of Technology
MIT
Cambridge,MA02139
04-2103594 501(c)(3) 1,280,000       H. Gray Scholars - Faculty
(29) Princeton University
Princeton University
Princeton,NJ08540
21-0634501 501(c)(3) 1,280,000       H. Gray Scholars - Faculty
(30) UCLA
UCLA
Los Angeles,CA900246505
95-6006143 California 1,280,000       H. Gray Scholars - Faculty
(31) Stanford University
Stanford University
San Francisco,CA941444253
94-1156365 501(c)(3) 1,280,000       H. Gray Scholars - Faculty
(32) The Pennsylvania State University
The Pennsylvania State University
University Park,PA168027000
24-6000376 Pennsylvania 1,280,000       H. Gray Scholars - Faculty
(33) University of Minnesota Medical School
Univ of MN Medical School
Minneapolis,MN55455
41-6007513 Minnesota 1,280,000       H. Gray Scholars - Faculty
(34) Stanford University
Stanford University
San Francisco,CA941444253
94-1156365 501(c)(3) 745,789       H. Gray Scholars - Grant
(35) College of the Holy Cross
College of the Holy Cross
Worcester,MA016102395
04-2103558 501(c)(3) 100,000       Inclusive Excellence 3 Learning Community
(36) Drexel University
Drexel University
Philadelphia,PA19102
23-1352630 501(c)(3) 100,000       Inclusive Excellence 3 Learning Community
(37) Florida State University
Florida State University
Tallahassee,FL32310
59-3211153 Florida 100,000       Inclusive Excellence 3 Learning Community
(38) Franklin & Marshall College
Franklin Marshall College
Lancaster,PA17604
23-1352635 501(c)(3) 100,000       Inclusive Excellence 3 Learning Community
(39) University of Alaska Anchorage
University of Alaska Anchorage
Fairbanks,AK997756540
92-6000147 Alaska 100,000       Inclusive Excellence 3 Learning Community
(40) University of La Verne
University of La Verne
La Verne,CA91709
95-1644026 501(c)(3) 100,000       Inclusive Excellence 3 Learning Community
(41) University of Nebraska-Lincoln
University of Nebraska-Lincoln
Lincoln,NE68583
47-0049123 Nebraska 100,000       Inclusive Excellence 3 Learning Community
(42) Loudoun County Public Schools
Loudoun County Public Schools
Ashburn,VA20176
54-1603768 Virginia 3,000,000       Support of K-12 science education activities
(43) Allen Institute
Allen Institute
Seattle,WA981094307
91-2155317 501(c)(3) 2,900,000       Medical Research
(44) Memorial Sloan Kettering Cancer Ctr
Memorial Sloan Kettering Cancer Ctr
New York,NY10017
13-1924236 501(c)(3) 871,067       Medical Research
(45) Northwestern Univ
Northwestern Univ
Evanston,IL60208
36-2167817 501(c)(3) 376,403       Medical Research
(46) Harvard University
Harvard University
Cambridge,MA02138
04-2103580 501(c)(3) 1,429,799       Medical Research
(47) Rockefeller Univ
Rockefeller Univ
New York,NY10065
13-1624158 501(c)(3) 43,816       Medical Research
(48) The University Of Penn
The University Of Penn
Philadelphia,PA191046205
23-1352685 501(c)(3) 458,324       Medical Research
(49) UNC Chapel Hill
UNC Chapel Hill
Chapel Hill,NC275997248
56-6001393 North Carolina 2,026,905       Medical Research
(50) Whitehead Institute
Whitehead Institute
Cambridge,MA021421479
06-1043412 501(c)(3) 300,000       Medical Research
(51) Boys & Girls Clubs of Greater Washington
Boys-Girls Clubs of Gr Wash DC
Washington,DC20019
53-0236759 501(c)(3) 150,000       Support of K-12 science education activities
(52) Amer Society For Cell Biology
Amer Society For Cell Biology
Rockville,MD20852
39-6054285 501(c)(3) 50,000       Support for the San Francisco Declaration on Research Assessment (DORA)
(53) New Venture Fund
New Venture Fund
Washington,DC20036
20-5806345 501(c)(3) 100,000       Support of SPARC's Open Research Funders Group
(54) Association of American Universities
Assoc of American Universities
Washington,DC20005
52-1947112 501(c)(3) 403,163       SUPPORT FOR AAU LEARNING COMMUNITY
2
Enter total number of section 501(c)(3) and government organizations listed in the line 1 table ................. Bullet Image
54
3
Enter total number of other organizations listed in the line 1 table ........................ . Bullet Image
0
For Paperwork Reduction Act Notice, see the Instructions for Form 990.
Cat. No. 50055P
Schedule I (Form 990) 2021

Schedule I (Form 990) 2021
Page 2
Part III
Grants and Other Assistance to Domestic Individuals. Complete if the organization answered "Yes" on Form 990, Part IV, line 22.
Part III can be duplicated if additional space is needed.
(a) Type of grant or assistance (b) Number of
recipients
(c) Amount of
cash grant
(d) Amount of
noncash assistance
(e) Method of valuation (book,
FMV, appraisal, other)
(f) Description of noncash assistance
(1) GILLIAM FELLOWSHIPS 54 8,359,000      
(2) FACULTY SCHOLARS 1 204,780      
(2)
(3)
(4)
(5)
(6)
(7)
Part IV
Supplemental Information. Provide the information required in Part I, line 2; Part III, column (b); and any other additional information.
Return Reference Explanation
Schedule I, Part I, Line 2 Procedures for monitoring use of grant funds. HHMI AWARDS INSTITUTIONAL GRANTS IN SUPPORT OF PRECOLLEGE, UNDERGRADUATE, AND GRADUATE EDUCATION IN THE US THROUGH PERIODIC NATIONAL COMPETITIONS FOR WHICH SELECT INSTITUTIONS ARE ELIGIBLE TO APPLY. EACH PROGRAM SETS OUT SPECIFIC CRITERIA AND OBJECTIVES, PROPOSALS ARE EVALUATED BY A PANEL OF EXPERTS WITH THE FINAL SELECTION MADE BY HHMI LEADERSHIP. THE INSTITUTE ALSO AWARDS FELLOWSHIPS TO DOCTORAL STUDENTS (THE GILLIAM FELLOWS). THESE GRANTS ARE ALSO AWARDED ON A COMPETITIVE BASIS. A SMALL NUMBER OF GRANTS ARE AWARDED BASED ON DIRECT APPLICATION TO HHMI FOR SPECIFIC INITIATIVES DIRECTLY RELATED TO SCIENCE EDUCATION. THE DISBURSEMENT OF FUNDS OCCURS PRINCIPALLY THROUGH BIOMEDICAL RESEARCH INSTITUTIONS, UNIVERSITIES, AND COLLEGES. HHMI GRANTEES ARE REQUIRED TO FILE ANNUAL PROGRESS REPORTS THAT DETAIL EXPENDITURES IN ACCORDANCE WITH THE TERMS OF THE GRANT, AS WELL AS FULL DESCRIPTION OF PROGRAM ACTIVITIES UNDERTAKEN WITH THE FUNDS. THESE ARE SUBJECT TO CAREFUL REVIEW AND ANALYSIS BY HHMI STAFF WITH MORE DETAILED REVIEW BY THE INSTITUTE AUDITORS AS WARRANTED. THE INSTITUTE CONTINUES TO ASSESS REPORTING REQUIREMENTS TO ENSURE THE QUALITY AND TIMELINESS OF BOTH FINANCIAL AND PROGRAMMATIC REPORTS. IN ADDITION TO SITE VISITS MADE BY HHMI STAFF, PROGRAM DIRECTORS MEET ON A REGULAR BASIS TO DISCUSS THEIR ACTIVITIES AND SHARE INFORMATION ABOUT BEST EDUCATIONAL PRACTICES.
Schedule I (Form 990) 2021



Additional Data


Software ID: 21014044
Software Version: 2021v4.2


Schedule J
(Form 990)
Department of the Treasury
Internal Revenue Service
Compensation Information
For certain Officers, Directors, Trustees, Key Employees, and Highest
Compensated Employees
SchJMediumBullet Complete if the organization answered "Yes" on Form 990, Part IV, line 23.
SchJMediumBullet Attach to Form 990.
SchJMediumBullet Go to www.irs.gov/Form990 for instructions and the latest information.
OMB No. 1545-0047
2021
Open to Public Inspection
Name of the organization
Howard Hughes Medical Institute
 
Employer identification number

59-0735717
Part I
Questions Regarding Compensation
Yes
No
1a
Check the appropiate box(es) if the organization provided any of the following to or for a person listed on Form
990, Part VII, Section A, line 1a. Complete Part III to provide any relevant information regarding these items.
b
If any of the boxes on Line 1a are checked, did the organization follow a written policy regarding payment or reimbursement or provision of all of the expenses described above? If "No," complete Part III to explain .....
1b
Yes
 
2
Did the organization require substantiation prior to reimbursing or allowing expenses incurred by all
directors, trustees, officers, including the CEO/Executive Director, regarding the items checked on Line 1a? ....
2
Yes
 
3
Indicate which, if any, of the following the filing organization used to establish the compensation of the
organization's CEO/Executive Director. Check all that apply. Do not check any boxes for methods
used by a related organization to establish compensation of the CEO/Executive Director, but explain in Part III.
4
During the year, did any person listed on Form 990, Part VII, Section A, line 1a, with respect to the filing organization or a related organization:
a
Receive a severance payment or change-of-control payment? .............
4a
 
No
b
Participate in, or receive payment from, a supplemental nonqualified retirement plan? .........
4b
 
No
c
Participate in, or receive payment from, an equity-based compensation arrangement? .........
4c
 
No
If "Yes" to any of lines 4a-c, list the persons and provide the applicable amounts for each item in Part III.
Only 501(c)(3), 501(c)(4), and 501(c)(29) organizations must complete lines 5-9.
5
For persons listed on Form 990, Part VII, Section A, line 1a, did the organization pay or accrue any
compensation contingent on the revenues of:
a
The organization? ....................
5a
 
No
b
Any related organization? .......................
5b
 
No
If "Yes," on line 5a or 5b, describe in Part III.
6
For persons listed on Form 990, Part VII, Section A, line 1a, did the organization pay or accrue any
compensation contingent on the net earnings of:
a
The organization? ..................
6a
 
No
b
Any related organization? ......................
6b
 
No
If "Yes," on line 6a or 6b, describe in Part III.
7
For persons listed on Form 990, Part VII, Section A, line 1a, did the organization provide any nonfixed
payments not described in lines 5 and 6? If "Yes," describe in Part III ............
7
Yes
 
8
Were any amounts reported on Form 990, Part VII, paid or accured pursuant to a contract that was
subject to the initial contract exception described in Regulations section 53.4958-4(a)(3)? If "Yes," describe
in Part III ..........................
8
Yes
 
9
If "Yes" on line 8, did the organization also follow the rebuttable presumption procedure described in Regulations section 53.4958-6(c)? .........................
9
Yes
 
For Paperwork Reduction Act Notice, see the Instructions for Form 990.
Cat. No. 50053T
Schedule J (Form 990) 2021

Schedule J (Form 990) 2021
Page 2
Part II
Officers, Directors, Trustees, Key Employees, and Highest Compensated Employees. Use duplicate copies if additional space is needed.
For each individual whose compensation must be reported on Schedule J, report compensation from the organization on row (i) and from related organizations, described in the
instructions, on row (ii). Do not list any individuals that are not listed on Form 990, Part VII.
Note. The sum of columns (B)(i)-(iii) for each listed individual must equal the total amount of Form 990, Part VII, Section A, line 1a, applicable column (D) and (E) amounts for that individual.
(A) Name and Title (B) Breakdown of W-2, 1099-MISC compensation, and/or 1099-NEC (C) Retirement and other deferred compensation (D) Nontaxable
benefits
(E) Total of columns
(B)(i)-(D)
(F) Compensation in column (B) reported as deferred on prior Form 990
(i) Base
compensation
(ii) Bonus & incentive
compensation
(iii) Other reportable compensation
1BODO STERN PHD
 
CHIEF OF STRATEGIC INITIATIVES
(i)

(ii)
371,073
-------------
0
0
-------------
0
34,576
-------------
0
29,000
-------------
0
16,026
-------------
0
450,675
-------------
0
0
-------------
0
2SUSAN S PLOTNICK
 
DIRECTOR OF FINANCE & ASSISTANT TREASURER (THRU 6/22)
(i)

(ii)
236,436
-------------
0
0
-------------
0
30,426
-------------
0
26,597
-------------
0
31,505
-------------
0
324,964
-------------
0
0
-------------
0
3MONIQUE L MARCUS
 
CONTROLLER
(i)

(ii)
231,875
-------------
0
0
-------------
0
10,943
-------------
0
24,187
-------------
0
36,329
-------------
0
303,334
-------------
0
0
-------------
0
4LAUREN T SPILIOTES ESQ
 
DEPUTY GENERAL COUNSEL & ASSISTANT SECRETARY (THRU 1/22)
(i)

(ii)
449,272
-------------
0
0
-------------
0
38,654
-------------
0
29,000
-------------
0
28,209
-------------
0
545,135
-------------
0
0
-------------
0
5SEAN B CARROLL PHD
 
VP FOR SCIENCE EDUCATION
(i)

(ii)
760,694
-------------
0
0
-------------
0
50,640
-------------
0
29,000
-------------
0
27,642
-------------
0
867,976
-------------
0
0
-------------
0
6DANIEL A CRONIN MBA PHD
 
VP & CHIEF FINANCIAL & OPERATING OFFICER
(i)

(ii)
621,699
-------------
0
50,000
-------------
0
42,225
-------------
0
29,000
-------------
0
12,906
-------------
0
755,830
-------------
0
0
-------------
0
7HEIDI E HENNING ESQ
 
VP & GENERAL COUNSEL & SECRETARY
(i)

(ii)
682,325
-------------
0
0
-------------
0
47,796
-------------
0
29,000
-------------
0
42,604
-------------
0
801,725
-------------
0
0
-------------
0
8RONALD VALE PHD
 
VP & EXEC DIR, JANELIA RESEARCH CAMPUS
(i)

(ii)
688,016
-------------
0
50,000
-------------
0
27,555
-------------
0
29,000
-------------
0
34,866
-------------
0
829,437
-------------
0
0
-------------
0
9DONALD KOCH
 
VP & CHIEF INVESTMENT OFFICER
(i)

(ii)
805,028
-------------
0
534,180
-------------
0
40,116
-------------
0
29,000
-------------
0
39,162
-------------
0
1,447,486
-------------
0
0
-------------
0
10JEREMY COMPTON
 
ASSOCIATE COMPTROLLER (AS OF 5/22)
(i)

(ii)
171,082
-------------
0
0
-------------
0
6,301
-------------
0
17,218
-------------
0
11,819
-------------
0
206,420
-------------
0
0
-------------
0
11ERIN K O'SHEA PHD
 
PRESIDENT
(i)

(ii)
1,412,299
-------------
0
0
-------------
0
72,250
-------------
0
29,000
-------------
0
35,350
-------------
0
1,548,899
-------------
0
0
-------------
0
12DAVID E CLAPHAM PHD
 
VP & CHIEF SCIENTIFIC OFFICER (THRU 1/22)/SENIOR GROUP LEADER
(i)

(ii)
690,448
-------------
0
0
-------------
0
91,679
-------------
0
29,000
-------------
0
42,809
-------------
0
853,936
-------------
0
0
-------------
0
13LESLIE B VOSSHALL PHD
 
INVESTIGATOR/VP & CHIEF SCIENTIFIC OFFICER (AS OF 2/22)
(i)

(ii)
326,859
-------------
0
0
-------------
0
385,657
-------------
0
29,000
-------------
0
36,832
-------------
0
778,348
-------------
0
0
-------------
0
14ANN K BATLLE ESQ
 
DEPUTY GENERAL COUNSEL & ASSISTANT SECRETARY (AS OF 1/22)
(i)

(ii)
272,621
-------------
0
0
-------------
0
10,207
-------------
0
28,267
-------------
0
33,722
-------------
0
344,817
-------------
0
0
-------------
0
15GLEN ZWICKER
 
MANAGING DIRECTOR & HEAD OF INVESTMENT OPS
(i)

(ii)
490,350
-------------
0
468,463
-------------
0
38,030
-------------
0
29,000
-------------
0
38,298
-------------
0
1,064,141
-------------
0
0
-------------
0
16ERIC KANDEL MD
 
INVESTIGATOR
(i)

(ii)
763,985
-------------
0
0
-------------
0
59,622
-------------
0
29,000
-------------
0
41,910
-------------
0
894,517
-------------
0
0
-------------
0
17GREGORY DENINNO
 
MANAGING DIRECTOR, PRIVATE MARKETS
(i)

(ii)
466,526
-------------
0
776,049
-------------
0
37,146
-------------
0
29,000
-------------
0
21,754
-------------
0
1,330,475
-------------
0
0
-------------
0
18RICHARD A PENDER
 
MANAGING DIRECTOR, PUBLIC MARKETS
(i)

(ii)
546,151
-------------
0
891,582
-------------
0
42,355
-------------
0
29,000
-------------
0
35,173
-------------
0
1,544,261
-------------
0
0
-------------
0
19LANDIS ZIMMERMAN
 
VP & CHIEF INVESTMENT OFFICER (THRU 6/21)
(i)

(ii)
558,981
-------------
0
1,014,806
-------------
0
14,648
-------------
0
29,000
-------------
0
17,481
-------------
0
1,634,916
-------------
0
0
-------------
0
20ROBERT J KOLYER JR
 
MANAGING DIRECTOR, DIVERSIFYING ASSETS (THRU 6/21)
(i)

(ii)
279,552
-------------
0
364,348
-------------
0
110,075
-------------
0
29,000
-------------
0
19,862
-------------
0
802,837
-------------
0
0
-------------
0
21GERALD M RUBIN PHD
 
SENIOR GROUP LEADER/FORMER VP&EXEC DIR, JRC
(i)

(ii)
516,128
-------------
0
0
-------------
0
48,133
-------------
0
29,000
-------------
0
36,745
-------------
0
630,006
-------------
0
0
-------------
0
22DENNIS MCKEARIN PHD
 
SENIOR SCIENTIFIC OFFICER/FORMER VP OF OPERATIONS
(i)

(ii)
424,749
-------------
0
0
-------------
0
20,154
-------------
0
29,000
-------------
0
33,548
-------------
0
507,451
-------------
0
0
-------------
0
Schedule J (Form 990) 2021

Schedule J (Form 990) 2021
Page 3
Part III
Supplemental Information
Provide the information, explanation, or descriptions required for Part I, lines 1a, 1b, 3, 4a, 4b, 4c, 5a, 5b, 6a, 6b, 7, and 8, and for Part II. Also complete this part for any additional information.
Return Reference Explanation
Schedule J, Part I, Line 1a First-class or charter travel UNDER HHMI POLICIES, HHMI REIMBURSES ITS TRUSTEES FOR THE REASONABLE COST OF AIRFARE ONE CLASS ABOVE COACH FOR DOMESTIC OR INTERNATIONAL FLIGHTS, AND ITS PRESIDENT, VICE PRESIDENTS, AND CERTAIN ADVISORY GROUP MEMBERS FOR THE REASONABLE COST OF AIRFARE AT ONE CLASS ABOVE COACH FOR DOMESTIC OR INTERNATIONAL FLIGHTS OF THREE HOURS OR MORE. IF A PARTICULAR AIRCRAFT DOES NOT HAVE A BUSINESS CLASS SECTION, ONE CLASS ABOVE COACH MAY BE FIRST CLASS. AS AN ALTERNATIVE, HHMI MAY REIMBURSE FOR THE COST OF COACH AIRFARE PLUS THE COST OF AN UPGRADE TO TRAVEL AT ONE LEVEL ABOVE COACH FOR A FLIGHT OF THREE HOURS OR MORE. SUCH TRAVEL REIMBURSEMENTS ARE EXCLUDED FROM TAXABLE COMPENSATION IN ACCORDANCE WITH HHMI'S ACCOUNTABLE PLAN. DURING FISCAL YEAR 2022, 2 OFFICERS AND 3 TRUSTEES FLEW FIRST CLASS.
Schedule J, Part I, Line 1a Housing allowance or residence for personal use IN FISCAL YEAR 2022, HHMI'S PRESIDENT RESIDES IN AN HHMI-OWNED HOUSE ON THE HEADQUARTERS CAMPUS. THROUGH JANUARY 2022, SHE PAID HHMI A FAIR MARKET RENTAL RATE. AS OF FEBRUARY 2022, SHE IS REQUIRED TO LIVE IN THIS RESIDENCE AS A CONDITION OF EMPLOYMENT. BECAUSE HHMI'S PRESIDENT IS ALSO REQUIRED TO SPEND TIME AT HHMI'S JANELIA CAMPUS, WHERE SHE RUNS A RESEARCH LABORATORY, ATTENDS MEETINGS, AND PARTICIPATES IN CONFERENCES, HHMI MAKES AN APARTMENT AVAILABLE TO HER AT THAT LOCATION. ALSO IN FISCAL YEAR 2022, HHMI'S VICE PRESIDENT AND EXECUTIVE DIRECTOR, JANELIA RESEARCH CAMPUS, IS REQUIRED AS A CONDITION OF EMPLOYMENT TO RESIDE ON THE JANELIA CAMPUS IN HOUSING BUILT FOR THAT PURPOSE. THE INSTITUTE PROVIDED A HOUSING ASSISTANCE PROGRAM FOR AN OFFICER WHO RELOCATED TO TAKE A POSITION WITH HHMI, WHICH MAY BE USED TO COVER THE INDIVIDUAL'S MORTGAGE OR RENT PAYMENTS. THE HOUSING ASSISTANCE PROGRAM IS TREATED AS ADDITIONAL TAXABLE COMPENSATION.
Schedule J, Part I, Line 7 Non-fixed payments HHMI HAS AN INCENTIVE COMPENSATION PLAN FOR ITS SENIOR INVESTMENT STAFF WHICH PROVIDES AN INCENTIVE AWARD THAT INCLUDES A QUANTITATIVE COMPONENT BASED ON PERFORMANCE OF HHMI'S PORTFOLIO AGAINST MARKET BENCHMARKS AND A DISCRETIONARY COMPONENT BASED ON EXCEPTIONAL PERFORMANCE TIED TO CERTAIN ATTRIBUTES THAT ARE NOT TIED TO INVESTMENT PERFORMANCE. AWARDS ARE APPROVED BY THE TRUSTEES IN RELIANCE ON COMPARABILITY DATA AND A REASONABLENESS OPINION PROVIDED BY AN INDEPENDENT COMPENSATION CONSULTANT. HHMI ALSO MAKES ONE-TIME PAYMENTS TO SOME OF ITS OTHER EMPLOYEES, INCLUDING BUT NOT LIMITED TO OFFICERS, IN RECOGNITION OF EXCEPTIONAL PERFORMANCE.
Schedule J, Part I, Line 8 Payments on contract that is subject to the initial contract exception WHEN RECRUITING INDIVIDUALS FOR HIGH-LEVEL POSITIONS, HHMI TYPICALLY ENTERS INTO INITIAL CONTRACTS. HHMI HAS ENTERED INTO INITIAL CONTRACTS WITH A NUMBER OF VICE PRESIDENTS. HHMI'S STANDARD PRACTICE IS TO HAVE INDEPENDENT COMPENSATION CONSULTANTS REGULARLY REVIEW AND CONFIRM THE REASONABLENESS OF COMPENSATION OF HHMI'S OFFICERS AND KEY EMPLOYEES, REGARDLESS OF WHETHER THE INITIAL CONTRACT EXCEPTION APPLIES.
Schedule J (Form 990) 2021

Additional Data


Software ID: 21014044
Software Version: 2021v4.2

Note: To capture the full content of this document, please select landscape mode (11" x 8.5") when printing.

Schedule K
(Form 990)
Department of the Treasury
Internal Revenue Service
Supplemental Information on Tax-Exempt Bonds
SchKMediumBullet Complete if the organization answered "Yes" to Form 990, Part , line 24a. Provide descriptions,
explanations, and any additional information in Part .
SchKMediumBullet Attach to Form 990.

SchKMediumBulletGo to www.irs.gov/Form990 for instructions and the latest information.
OMB No. 1545-0047
2021
Open to Public
Inspection
Name of the organization
Howard Hughes Medical Institute
 
Employer identification number
59-0735717
Part
Bond Issues
(a) Issuer name (b) Issuer EIN (c) CUSIP # (d) Date issued (e) Issue price (f) Description of purpose (g) Defeased (h) On
behalf of
issuer
(i) Pool
financing
Yes No Yes No Yes No
A LOUDOUN COUNTY IDA
 
52-1310230 545910AL5 02-27-2003 500,000,000 FINANCE CONSTRUCTION OF JANELIA RESEARCH CAMPUS   X   X   X
B LOUDOUN COUNTY IDA
 
52-1310230 545910AP6 10-02-2009 23,000,000 FINANCE CONSTRUCTION OF JANELIA APT   X   X   X
C LOUDOUN COUNTY IDA
 
52-1310230 545910AQ4 05-15-2013 33,130,000 FINANCE CONSTRUCTION OF JANELIA APT B   X   X   X
D MEDCO
 
52-1376562 574205FY1 02-15-2008 83,500,000 FINANCE CONSTRUCTION OF HQ EXPANSION   X   X   X
MEDCO
 
52-1376562 574205FZ8 05-15-2008 76,500,000 REFUNDING OF ISSUE TO FINANCE HQ CONSTRUCTION ORIGINALLY ISSUED 11/08/1990   X   X   X
LOUDOUN COUNTY IDA
 
52-1310230 54601TAA4 06-06-2019 51,773,425 FINANCE CONSTRUCTION OF JANELIA APT C   X   X   X
Part
Proceeds
A B C D
1 Amount of bonds retired .................. 0 0 0 0
2 Amount of bonds legally defeased .............. 0 0 0 0
3 Total proceeds of issue .................. 534,028,000 23,022,042 33,145,417 84,953,297
4 Gross proceeds in reserve funds ............. 0 0 0 0
5 Capitalized interest from proceeds ............. 54,203,000 904,914 1,173,864 5,954,687
6 Proceeds in refunding escrows ............... 0 0 0 0
7 Issuance costs from proceeds ............... 200,000 0 397,311 631,673
8 Credit enhancement from proceeds ............. 0 0 0 0
9 Working capital expenditures from proceeds ............. 0 43,305 0 0
10 Capital expenditures from proceeds ............. 479,625,000 22,073,823 31,574,242 78,366,937
11 Other spent proceeds ............. 0 0 0 0
12 Other unspent proceeds ............. 0 0 0 0
13 Year of substantial completion ............. 2006 2011 2015 2010
Yes No Yes No Yes No Yes No
14 Were the bonds issued as part of a current refunding issue of tax-exempt
bonds (or, if issued prior to 2020, a current refunding issue)? ........
  X   X   X   X
15 Were the bonds issued as part of an advance refunding issue of taxable
bonds (or, if issued prior to 2020, an advance refunding issue)? ........
  X   X   X   X
16 Has the final allocation of proceeds been made? .......... X   X   X   X  
17 Does the organization maintain adequate books and records to support the final allocation of proceeds? .................. X   X   X   X  
For Paperwork Reduction Act Notice, see the Instructions for Form 990.
Cat. No. 50193E
Schedule K (Form 990) 2021

Schedule K (Form 990) 2021
Page 2
Part
Private Business Use
A B C D
Yes No Yes No Yes No Yes No
1 Was the organization a partner in a partnership, or a member of an LLC, which owned property financed by tax-exempt bonds? .............   X   X   X   X
2 Are there any lease arrangements that may result in private business use of bond-financed property? ...............   X   X   X   X
3a Are there any management or service contracts that may result in private business use of bond-financed property? ............. X   X   X   X  
b If "Yes" to line 3a, does the organization routinely engage bond counsel or other outside counsel to review any management or service contracts relating to the financed property? X   X   X   X  
c Are there any research agreements that may result in private business use of bond-financed property? ............. X     X   X   X
d If "Yes" to line 3c, does the organization routinely engage bond counsel or other outside counsel to review any research agreements relating to the financed property? X              
4 Enter the percentage of financed property used in a private business use by entities other than a section 501(c)(3) organization or a state or local government ....SchKMediumBullet 0 % 0 % 0 % 0 %
5 Enter the percentage of financed property used in a private business use as a result of unrelated trade or business activity carried on by your organization, another section 501(c)(3) organization, or a state or local government ......... SchKMediumBullet 0 % 0 % 0 % 0 %
6 Total of lines 4 and 5 ............. 0 % 0 % 0 % 0 %
7 Does the bond issue meet the private security or payment test? ...   X   X   X   X
8a Has there been a sale or disposition of any of the bond-financed property to a nongovernmental person other than a 501(c)(3) organization since the bonds were issued?.............   X   X   X   X
b If "Yes" to line 8a, enter the percentage of bond-financed property sold or disposed of. ..        
c If "Yes" to line 8a, was any remedial action taken pursuant to Regulations sections 1.141-12 and 1.145-2? .............                
9 Has the organization established written procedures to ensure that all nonqualified bonds of the issue are remediated in accordance with the requirements under
Regulations sections 1.141-12 and 1.145-2? ........
  X   X   X   X
Part
Arbitrage
A B C D
Yes No Yes No Yes No Yes No
1 Has the issuer filed Form 8038-T, Arbitrage Rebate, Yield Reduction and Penalty in Lieu of Arbitrage Rebate? ... X     X   X   X
2 If "No" to line 1, did the following apply? ....
a Rebate not due yet? .......       X   X   X
b Exception to rebate? ........ X     X   X   X
c No rebate due? .........     X   X   X  
If "Yes" to line 2c, provide in Part the date the rebate
computation was performed ......
3 Is the bond issue a variable rate issue? ..... X   X   X   X  
Schedule K (Form 990) 2021

Schedule K (Form 990) 2021
Page 3
Part
Arbitrage (Continued)
A B C D
Yes No Yes No Yes No Yes No
4a Has the organization or the governmental issuer entered into a qualified hedge with respect to the bond issue? X   X   X   X  
b Name of provider .......... WELLS FARGO
 
JPMORGAN CHASE
 
WELLS FARGO BANK
 
JP MORGAN
 
c Term of hedge ......... 2000 % 3000 % 3000 % 3000 %
d Was the hedge superintegrated? ......   X   X   X   X
e Was the hedge terminated? ........   X   X   X   X
5a Were gross proceeds invested in a guaranteed investment contract (GIC)?   X   X   X   X
b Name of provider ..........  
 
 
 
 
 
 
 
c Term of GIC .........        
d Was the regulatory safe harbor for establishing the fair market value of the GIC satisfied? ........                
6 Were any gross proceeds invested beyond an available temporary period?   X   X   X   X
7 Has the organization established written procedures to monitor the requirements of section 148? ... X   X   X   X  
Part
Procedures To Undertake Corrective Action
--------------------------------------------------------------------------------------------------------------- A B C D
Yes No Yes No Yes No Yes No
Has the organization established written procedures to ensure that violations of federal tax requirements are timely identified and corrected through the voluntary closing agreement program if self-remediation is not available under applicable regulations?   X   X   X   X
Part
Supplemental Information. Provide additional information for responses to questions on Schedule K. (See instructions).
Return Reference Explanation
Schedule K, Part I Part I The bond issued February 27, 2003 also includes CUSIPS 545910AM3, 545910AG6, 545910AH4, 545910AJO, and 545910AK7.
Schedule K, Part II, Line 3 Part II, Line 3 - Total Proceeds The bonds issued on 2/27/2003, 10/2/2009, 2/15/2008, 5/15/2013 and 6/6/2019 included investment proceeds that made up the difference between the amount of the bond issue and the total proceeds.
Schedule K, Part IV Part IV - Name of Provider The other counterparties pertaining to the bond issued on 2/27/2003 were Bank of America (30 years), Goldman Sachs (30 years) and JP Morgan (30 years.)
Schedule K, Part IV, Line 4a Part IV, Line 4a Yes, for the bonds issued on 2/27/2003, 10/2/2009, 2/15/2008, 5/15/2008 and 5/15/2013.
Schedule K, Part IV, Line 2c COLUMN B Issuer name: LOUDOUN COUNTY IDA The calculation for computing no rebate due was performed on 10/07/2019
Schedule K, Part IV, Line 2c COLUMN C Issuer name: LOUDOUN COUNTY IDA The calculation for computing no rebate due was performed on 05/09/2018
Schedule K, Part IV, Line 2c COLUMN D Issuer name: MEDCO The calculation for computing no rebate due was performed on 02/19/2018
Schedule K (Form 990) 2021

Additional Data


Software ID: 21014044
Software Version: 2021v4.2


Note: To capture the full content of this document, please select landscape mode (11" x 8.5") when printing.

Schedule K
(Form 990)
Department of the Treasury
Internal Revenue Service
Supplemental Information on Tax-Exempt Bonds
SchKMediumBullet Complete if the organization answered "Yes" to Form 990, Part , line 24a. Provide descriptions,
explanations, and any additional information in Part .
SchKMediumBullet Attach to Form 990.

SchKMediumBulletGo to www.irs.gov/Form990 for instructions and the latest information.
OMB No. 1545-0047
2021
Open to Public
Inspection
Name of the organization
Howard Hughes Medical Institute
 
Employer identification number
59-0735717
Part
Bond Issues
(a) Issuer name (b) Issuer EIN (c) CUSIP # (d) Date issued (e) Issue price (f) Description of purpose (g) Defeased (h) On
behalf of
issuer
(i) Pool
financing
Yes No Yes No Yes No
A LOUDOUN COUNTY IDA
 
52-1310230 545910AL5 02-27-2003 500,000,000 FINANCE CONSTRUCTION OF JANELIA RESEARCH CAMPUS   X   X   X
B LOUDOUN COUNTY IDA
 
52-1310230 545910AP6 10-02-2009 23,000,000 FINANCE CONSTRUCTION OF JANELIA APT   X   X   X
C LOUDOUN COUNTY IDA
 
52-1310230 545910AQ4 05-15-2013 33,130,000 FINANCE CONSTRUCTION OF JANELIA APT B   X   X   X
D MEDCO
 
52-1376562 574205FY1 02-15-2008 83,500,000 FINANCE CONSTRUCTION OF HQ EXPANSION   X   X   X
MEDCO
 
52-1376562 574205FZ8 05-15-2008 76,500,000 REFUNDING OF ISSUE TO FINANCE HQ CONSTRUCTION ORIGINALLY ISSUED 11/08/1990   X   X   X
LOUDOUN COUNTY IDA
 
52-1310230 54601TAA4 06-06-2019 51,773,425 FINANCE CONSTRUCTION OF JANELIA APT C   X   X   X
Part
Proceeds
A B C D
1 Amount of bonds retired .................. 0 0 0 0
2 Amount of bonds legally defeased .............. 0 0 0 0
3 Total proceeds of issue .................. 534,028,000 23,022,042 33,145,417 84,953,297
4 Gross proceeds in reserve funds ............. 0 0 0 0
5 Capitalized interest from proceeds ............. 54,203,000 904,914 1,173,864 5,954,687
6 Proceeds in refunding escrows ............... 0 0 0 0
7 Issuance costs from proceeds ............... 200,000 0 397,311 631,673
8 Credit enhancement from proceeds ............. 0 0 0 0
9 Working capital expenditures from proceeds ............. 0 43,305 0 0
10 Capital expenditures from proceeds ............. 479,625,000 22,073,823 31,574,242 78,366,937
11 Other spent proceeds ............. 0 0 0 0
12 Other unspent proceeds ............. 0 0 0 0
13 Year of substantial completion ............. 2006 2011 2015 2010
Yes No Yes No Yes No Yes No
14 Were the bonds issued as part of a current refunding issue of tax-exempt
bonds (or, if issued prior to 2020, a current refunding issue)? ........
  X   X   X   X
15 Were the bonds issued as part of an advance refunding issue of taxable
bonds (or, if issued prior to 2020, an advance refunding issue)? ........
  X   X   X   X
16 Has the final allocation of proceeds been made? .......... X   X   X   X  
17 Does the organization maintain adequate books and records to support the final allocation of proceeds? .................. X   X   X   X  
For Paperwork Reduction Act Notice, see the Instructions for Form 990.
Cat. No. 50193E
Schedule K (Form 990) 2021

Schedule K (Form 990) 2021
Page 2
Part
Private Business Use
A B C D
Yes No Yes No Yes No Yes No
1 Was the organization a partner in a partnership, or a member of an LLC, which owned property financed by tax-exempt bonds? .............   X   X   X   X
2 Are there any lease arrangements that may result in private business use of bond-financed property? ...............   X   X   X   X
3a Are there any management or service contracts that may result in private business use of bond-financed property? ............. X   X   X   X  
b If "Yes" to line 3a, does the organization routinely engage bond counsel or other outside counsel to review any management or service contracts relating to the financed property? X   X   X   X  
c Are there any research agreements that may result in private business use of bond-financed property? ............. X     X   X   X
d If "Yes" to line 3c, does the organization routinely engage bond counsel or other outside counsel to review any research agreements relating to the financed property? X              
4 Enter the percentage of financed property used in a private business use by entities other than a section 501(c)(3) organization or a state or local government ....SchKMediumBullet 0 % 0 % 0 % 0 %
5 Enter the percentage of financed property used in a private business use as a result of unrelated trade or business activity carried on by your organization, another section 501(c)(3) organization, or a state or local government ......... SchKMediumBullet 0 % 0 % 0 % 0 %
6 Total of lines 4 and 5 ............. 0 % 0 % 0 % 0 %
7 Does the bond issue meet the private security or payment test? ...   X   X   X   X
8a Has there been a sale or disposition of any of the bond-financed property to a nongovernmental person other than a 501(c)(3) organization since the bonds were issued?.............   X   X   X   X
b If "Yes" to line 8a, enter the percentage of bond-financed property sold or disposed of. ..        
c If "Yes" to line 8a, was any remedial action taken pursuant to Regulations sections 1.141-12 and 1.145-2? .............                
9 Has the organization established written procedures to ensure that all nonqualified bonds of the issue are remediated in accordance with the requirements under
Regulations sections 1.141-12 and 1.145-2? ........
  X   X   X   X
Part
Arbitrage
A B C D
Yes No Yes No Yes No Yes No
1 Has the issuer filed Form 8038-T, Arbitrage Rebate, Yield Reduction and Penalty in Lieu of Arbitrage Rebate? ... X     X   X   X
2 If "No" to line 1, did the following apply? ....
a Rebate not due yet? .......       X   X   X
b Exception to rebate? ........ X     X   X   X
c No rebate due? .........     X   X   X  
If "Yes" to line 2c, provide in Part the date the rebate
computation was performed ......
3 Is the bond issue a variable rate issue? ..... X   X   X   X  
Schedule K (Form 990) 2021

Schedule K (Form 990) 2021
Page 3
Part
Arbitrage (Continued)
A B C D
Yes No Yes No Yes No Yes No
4a Has the organization or the governmental issuer entered into a qualified hedge with respect to the bond issue? X   X   X   X  
b Name of provider .......... WELLS FARGO
 
JPMORGAN CHASE
 
WELLS FARGO BANK
 
JP MORGAN
 
c Term of hedge ......... 2000 % 3000 % 3000 % 3000 %
d Was the hedge superintegrated? ......   X   X   X   X
e Was the hedge terminated? ........   X   X   X   X
5a Were gross proceeds invested in a guaranteed investment contract (GIC)?   X   X   X   X
b Name of provider ..........  
 
 
 
 
 
 
 
c Term of GIC .........        
d Was the regulatory safe harbor for establishing the fair market value of the GIC satisfied? ........                
6 Were any gross proceeds invested beyond an available temporary period?   X   X   X   X
7 Has the organization established written procedures to monitor the requirements of section 148? ... X   X   X   X  
Part
Procedures To Undertake Corrective Action
--------------------------------------------------------------------------------------------------------------- A B C D
Yes No Yes No Yes No Yes No
Has the organization established written procedures to ensure that violations of federal tax requirements are timely identified and corrected through the voluntary closing agreement program if self-remediation is not available under applicable regulations?   X   X   X   X
Part
Supplemental Information. Provide additional information for responses to questions on Schedule K. (See instructions).
Return Reference Explanation
Schedule K, Part I Part I The bond issued February 27, 2003 also includes CUSIPS 545910AM3, 545910AG6, 545910AH4, 545910AJO, and 545910AK7.
Schedule K, Part II, Line 3 Part II, Line 3 - Total Proceeds The bonds issued on 2/27/2003, 10/2/2009, 2/15/2008, 5/15/2013 and 6/6/2019 included investment proceeds that made up the difference between the amount of the bond issue and the total proceeds.
Schedule K, Part IV Part IV - Name of Provider The other counterparties pertaining to the bond issued on 2/27/2003 were Bank of America (30 years), Goldman Sachs (30 years) and JP Morgan (30 years.)
Schedule K, Part IV, Line 4a Part IV, Line 4a Yes, for the bonds issued on 2/27/2003, 10/2/2009, 2/15/2008, 5/15/2008 and 5/15/2013.
Schedule K, Part IV, Line 2c COLUMN B Issuer name: LOUDOUN COUNTY IDA The calculation for computing no rebate due was performed on 10/07/2019
Schedule K, Part IV, Line 2c COLUMN C Issuer name: LOUDOUN COUNTY IDA The calculation for computing no rebate due was performed on 05/09/2018
Schedule K, Part IV, Line 2c COLUMN D Issuer name: MEDCO The calculation for computing no rebate due was performed on 02/19/2018
Schedule K (Form 990) 2021

Additional Data


Software ID: 21014044
Software Version: 2021v4.2

Schedule L
(Form 990)
Department of the Treasury
Internal Revenue Service
Transactions with Interested Persons
MediumBullet Complete if the organization answered "Yes" on Form 990, Part IV, lines 25a, 25b, 26, 27, 28a, 28b, or 28c, or Form 990-EZ, Part V, line 38a or 40b.
MediumBullet Attach to Form 990 or Form 990-EZ.
MediumBulletGo to www.irs.gov/Form990 for instructions and the latest information.
OMB No. 1545-0047
2021
Open to Public Inspection
Name of the organization
Howard Hughes Medical Institute
 
Employer identification number

59-0735717
Part I
Excess Benefit Transactions (section 501(c)(3), section 501(c)(4), and section 501(c)(29) organizations only).
Complete if the organization answered "Yes" on Form 990, Part IV, line 25a or 25b, or Form 990-EZ, Part V, line 40b.
1(a) Name of disqualified person (b) Relationship between disqualified person and organization (c) Description of transaction (d) Corrected?
Yes No
2
Enter the amount of tax incurred by the organization managers or disqualified persons during the year under section 4958. ........................... Bullet Image$
 
3
Enter the amount of tax, if any, on line 2, above, reimbursed by the organization ........ Bullet Image$
 

Part II
Loans to and/or From Interested Persons.
Complete if the organization answered "Yes" on Form 990-EZ, Part V, line 38a, or Form 990, Part IV, line 26; or if the organization reported an amount on Form 990, Part X, line 5, 6, or 22
(a) Name of interested person (b) Relationship with organization (c) Purpose of loan (d) Loan to or from the organization? (e) Original principal amount (f) Balance due (g) In default? (h) Approved by board or committee? (i) Written agreement?
To From Yes No Yes No Yes No
Total ...............Small Bullet $  
Part III
Grants or Assistance Benefiting Interested Persons.
Complete if the organization answered "Yes" on Form 990, Part IV, line 27.
(a) Name of interested person (b) Relationship between interested person and the organization (c) Amount of assistance (d) Type of assistance (e) Purpose of assistance
For Paperwork Reduction Act Notice, see the Instructions for Form 990 or 990-EZ.
Cat. No. 50056A
Schedule L (Form 990) 2021
Schedule L (Form 990) 2021
Page 2
Part IV
Business Transactions Involving Interested Persons.
Complete if the organization answered "Yes" on Form 990, Part IV, line 28a, 28b, or 28c.
(a) Name of interested person (b) Relationship between interested person and the organization (c) Amount of transaction (d) Description of transaction (e) Sharing of organization's revenues?
Yes No
(1) VIKNESH SIVANATHAN
 
SPOUSE 168,808 SALARY & BENEFITS   No
Part V
Supplemental Information
Provide additional information for responses to questions on Schedule L (see instructions).
Return Reference Explanation
Schedule L, Part IV, Column (d) REPORTABLE BUSINESS TRANSACTIONS AN OFFICER OF THE CORPORATION IS MARRIED TO A STAFF MEMBER.
Schedule L (Form 990) 2021


Additional Data


Software ID: 21014044
Software Version: 2021v4.2




SCHEDULE O
(Form 990)

Department of the Treasury
Internal Revenue Service
Supplemental Information to Form 990 or 990-EZ

Complete to provide information for responses to specific questions on
Form 990 or 990-EZ or to provide any additional information.
MediumBullet Attach to Form 990 or 990-EZ.
MediumBullet Go to www.irs.gov/Form990 for the latest information.
OMB No. 1545-0047
2021
Open to Public
Inspection
Name of the organization
Howard Hughes Medical Institute
 
Employer identification number

59-0735717
Return Reference Explanation
Form 990, Part III, Line 4b Program Service Description Through its Science Education initiatives, HHMI invests in individuals, institutions, initiatives, and media that advance learning. HHMI also nourishes the public understanding of science by bringing important stories of scientific discovery to a wide variety of audiences. (A) Science Education Grant and Research Programs HHMI's Inclusive Excellence (IE) initiative aims to help colleges and universities increase their capacity for inclusion in science of all students, especially those students who come to college via non-traditional pathways. These new majority students include persons from groups excluded because of their ethnicity or race, first-generation college students, students who transfer from community colleges, and working adults with families. In two earlier rounds of competition (IE1 and IE2), 57 institutions were selected to receive five year grants beginning in 2017 and 2018. In the spring of 2019, HHMI announced the third round (IE3) of competition for the initiative, with the goal of adding more schools to the program in the fall of 2021. With the help of an external panel of experts, HHMI selected 108 finalists out of 354 proposals which were invited to form a Learning Community; 104 accepted the invitation and are organized into seven Learning Community Clusters (LCC) each of which comprises approximately 15 institutions. Each LCC is focused on one of three challenges: (i) improving the content of the introductory STEM curriculum, (ii) evaluating and rewarding inclusive teaching, or (iii) building genuine partnerships between two- and four-year institutions. During Phase One, each of the 104 finalist institutions was awarded a learning grant and each LCC a planning grant. These initial awards have been used by the schools to expand their understanding of the barriers to inclusion in the context of their selected challenge. In FY22, each of the LCCs collectively designed and proposed collaborative projects aimed at their respective challenge, and HHMI will begin funding the projects in the fall of 2022. HHMI completed a pilot project with the University of Maryland, Baltimore County (UMBC), the Pennsylvania State University, and the University of North Carolina at Chapel Hill, in the collaborative Meyerhoff Adaptation Project. The pilot project aims to learn whether elements of UMBC's highly regarded Meyerhoff Scholars Program can be adapted and successfully implemented at other research universities. Building on what is being learned through the Meyerhoff Adaptation Project pilot, in 2019 HHMI announced a new initiative called Driving Change, which, over four rounds of funding, will award up to 24 grants to US research universities. Driving Change grantees will: (i) develop and implement institution-centered activities aimed at creating a more inclusive STEM learning environment for all schools; (ii) develop and implement student-centered activities that will strive to achieve the outcomes of UMBC's Meyerhoff Scholars Program; and (iii) actively participate in a learning community of Driving Change institutions. In the first round, 99 universities submitted Letters of Intent, and 38 were selected as finalists. Over the last two-plus years, the finalists formed a learning community which meets regularly so that the finalist universities can share with one another what they are learning from their institutional self-studies. In FY22, HHMI received 25 proposals and, with the advice of peer reviewers, selected six universities as the first Driving Change cohort. The first grant payments will be distributed in the fall of 2022. The HHMI Professors Program empowers accomplished science faculty at leading research universities to apply the rigor and creativity that make them successful in research to important challenges in undergraduate science education. HHMI Professors model fundamental reform in the way undergraduate science is taught at research universities through innovative teaching and are encouraged to share ideas and collaborate with their peers to improve science education. In addition to their commitment to student learning, these highly visible scientists have developed new educational resources and implemented novel mentoring programs to support students. To date, 69 scientists have been named HHMI Professors. In FY22, the Science Education Alliance Phage Hunters Advancing Genomics and Evolutionary Science (SEA-PHAGES) added 11 colleges and universities to the alliance. Established in 2008, SEA-PHAGES is a two-semester course-based research experience designed to replace the traditional introductory biology lab sequence in the undergraduate curriculum. SEA-PHAGES students isolate and characterize bacteriophages which are viruses that infect bacteria. In the last 14 years (2008 - 2022), the SEA-PHAGES program has involved more than 40,000 students-primarily freshmen and sophomores-and 600 faculty at more than 200 colleges and universities in 45 states, Puerto Rico, and the District of Columbia. The project has produced more than 200 publications, many including SEA-PHAGES students and faculty as co-authors. In 2019, a second, more advanced course was created called SEA-GENES (Gene function Exploration by a Network of Emerging Scientists). In SEA-GENES, students use genetics and molecular biology methods to identify putative interactions between phage- and bacteria-encoded proteins, information which provides insights as to the function of the phage proteins. There are now 25 colleges and universities participating in SEA-GENES. HHMI's Gilliam Fellowships for Advanced Study Program supports PhD students who plan to pursue careers in academic science and who are committed to advancing diversity and inclusion in science. In FY22, HHMI made 51 new awards. Each award provides an annual payment of $53,000 for up to three years, which includes the fellow's stipend, a research allowance for the fellow, an institutional allowance to offset tuition and fees, and an allowance to support diversity and inclusion activities on the fellow's campus. In addition to supporting the graduate student, the award provides the fellow's dissertation adviser training in culturally aware mentoring. In FY22, HHMI continued support of three laboratories that provide professional development to scientists. The three grantee institutions are the Cold Spring Harbor Laboratory on Long Island, New York, the Jackson Laboratory in Bar Harbor, Maine, and the Marine Biological Laboratory in Woods Hole, Massachusetts. Together, the three institutions are important resources for the scientific community, annually engaging hundreds of scientists at different levels of professional development-graduate students, postdoctoral scientists, and faculty members-in advanced courses and workshops, mainly during the summer. In FY22, HHMI continued support of K-12 science education activities in Maryland and Virginia. These local grantee organizations include: the Audubon Naturalist Society, the Chesapeake Bay Foundation, Loudoun County (Virginia) Public Schools, Montgomery County (Maryland) Public Schools, and Prince George's (Maryland) Public Schools. HHMI funded programs include nature-based learning activities for students, parents, teachers, and principals; research internships for high school students; science curriculum development; professional development for middle school and high school teachers; and resource centers that enable teachers to provide authentic laboratory experiences for their students.
Form 990, Part III, Line 4b Program Service Description (Continued) (B) Educational Media Group HHMI BioInteractive, a resource for general high school biology, AP/IB biology, and college-level introductory biology teachers, has been in existence for over two decades and receives over three million visitors annually through its website, BioInteractive.org. The Educational Media Group produces BioInteractive's science education resources including interactive multimedia materials, scientific animations, videos, in-class activities, as well as award-winning, broadcast-quality short films. The resources are then made available to educators online, through the BioInteractive.org website and YouTube channel, and at workshops, conferences, and conventions. In 2022, after more than two years of COVID travel restrictions, the BioInteractive team and Ambassador Community members started to travel again to attend and present in-person educator professional development workshops at national, regional, and local educational conferences and events. Virtual workshops direct from BioInteractive were started during the COVID pandemic and continue to be popular and are now a regular part of BioInteractive's outreach. These virtual events reach a more diverse and inclusive audience, especially those unavailable to access educational conferences and organizations. On July 5-8, 2022, 60-plus BioInteractive Ambassadors met virtually to understand how science and society intermingle, with a focus on social inequities in STEM classrooms and building comfort and skills for facilitating difficult dialogues with students. On July 11-14, 2022, the 28 members of the 2020-2023 US BioInteractive Academy gathered for the first time in-person at HHMI's headquarters. The focus was development and presentation of BioInteractive workshops, giving and receiving feedback, and networking. Similarly, in December 2022 the 18 members of the 2020-2023 Mexico / Puerto Rico BioInteractive Ambassador Academy will gather in-person for the first time in Merida, Mexico. In July 2022, HHMI BioInteractive sponsored 50 staff and members of the Ambassador community to attend the July 21-23 National Science Teachers Association (NSTA) Conference in Chicago. In November 2022, BioInteractive sponsored over 100 individuals to attend the November 10-13 National Association of Biology Teachers (NABT) Conference in Indianapolis. HHMI BioInteractive offered twelve professional development workshops at NSTA and nine at NABT. In 2022 the Educational Media Group also developed and released a short video on genetic treatment for sickle cell disease and an interactive on exploring keystone species. (C) Tangled Bank Studios Tangled Bank Studios, LLC, is a mission-driven production company dedicated to crafting compelling, immersive films about science and scientists for broadcast, theatrical, and digital distribution. As an extension of HHMI's longstanding science education mission, the studio aims to produce programs that capture compelling stories of discovery across all branches of scientific inquiry, with particular focus on the life sciences. Together with world class partners, the studio creates innovative outreach initiatives to amplify the reach and deepen the impact around each project. New films released this year: ALL THAT BREATHES - The film, which premiered at the Sundance film festival and earned the award for best documentary, follows two brothers who devote their lives to rescuing a bird - the black kite. From the tiny basement of their family business, they rescue tens of thousands of these mesmeric creatures that drop daily from the thick grey skies, and dream of someday building a proper wildlife hospital. The film became the first film to win best documentary at both the Sundance and Cannes film festivals, and went on to a theatrical run in the US starting in October. Critics, filmmakers, festival directors and audiences have praised the film for its hopeful story and stunning cinematography. The film will premiere on HBO in early 2023. ENDING HIV IN AMERICA - The film, which premiered on PBS/NOVA on October 5, asks the question: could we be on the verge of ending the AIDS epidemic in America, almost 40 years after the discovery of HIV? The film explores how scientists tackled one of the most elusive deadly viruses to infect humans. It also takes a look at whether innovative drugs can bring new infections to zero. Outreach screenings around the film are aimed at vulnerable communities in the US. Film Updates: MY GARDEN OF A THOUSAND BEES - This film, which premiered on Nature/PBS in October 2021, follows wildlife filmmaker Martin Dohrn during the COVID-19 lockdown of spring and summer 2020, as he films more than 60 species of bees in his urban garden in Bristol, England. Dohrn observes how differences in behavior set different species apart from each other. Eventually, he gets so close to the bees, he can identify individuals just by looking at them. Surrounding the film, the studio launched an educational outreach effort featuring video shorts about bees created in partnership with digital media brand Seeker and educational materials created with World Wildlife Fund and PBS Learning. In 2022, the studio focused efforts on launching the largest outreach campaign to date in partnership with PBS/Nature and StarNet, a network of libraries across the US. The outreach effort hosted more than 700 events at libraries, nature centers and community centers. Event hosts screened the film, distributed native wildflower seeds, and shared information about the importance of native bees and other pollinators. The film was also screened at large events, including the Smithsonian Folklife Festival on the national mall, and won numerous top awards from Jackson Wild, Wildscreen, and Kavli. OLIVER SACKS: HIS OWN LIFE - Scheduled to debut theatrically in the spring of 2020, after debuting at the Telluride Film Festival in 2019, the film ultimately launched theatrically in September 2020. With most theaters closed, the film debuted in the US and Canada mostly virtually through an innovative new platform called Kino Marquee that allowed patrons to purchase tickets from their local theaters to receive a streaming link to watch the film at home. The New York Times selected the film as a critic's pick and wrote a glowing review of the film. The NYT review is one of a long list of positive reviews including Variety which called it a tender and thrilling look at the sacred demons that drove the poetic neurologist of 'Awakenings,' Science, AARP which listed it as one of the 20 must see films this Fall, and Gold Derby, which listed the film as a serious awards contender. The film premiered on American Masters on PBS in April 2021 and is now being offered for free streaming to educational audiences across the US. (D) Hanna H. Gray Fellows Program Since 2017, HHMI has held regular open competitions to recruit and retain early-career scientists who are from gender, racial, ethnic, and other groups underrepresented in the life sciences, including those from disadvantaged backgrounds. Each fellow receives funding for up to eight years, with mentoring and active involvement within the HHMI community. In this two-phase program, fellows are supported from early postdoctoral training through several years of a tenure-track faculty position. Through the current fiscal year, HHMI has selected 91 fellows to support, and will invest a total of up to $151 million for their support over eight years. A sixth competition is currently underway, with plans to select up to 25 new fellows by Summer 2023. (E) Faculty Scholars HHMI, together with the Simons Foundation, and the Bill & Melinda Gates Foundation continued to provide grant support to 67 Faculty Scholars during the current fiscal year, early-career scientists who have great potential to make unique contributions to their field. The scientists represent 36 institutions across the United States. Through the Faculty Scholars Program, HHMI and its partner philanthropies will spend up to $67.5 million over five years to support the scientists selected to receive grants. The range of five-year grant award totals is $600,000-$1.8 million, including indirect costs. Faculty Scholars are required to devote at least 50 percent of their total effort to the direct conduct of research. (F) eLife Open Access Journal HHMI, together with Wellcome, the Max Planck Society, and the Knut and Alice Wallenberg Foundation, continues to support a top tier scientific journal called eLife. The online journal follows an open access model and is directed by practicing scientists. eLife Sciences Publications, Ltd., is an independent non-profit entity governed by a separate board of directors. eLife began publishing research articles in late 2012 and publishes articles online on a regular basis.
Form 990, Part VI, Line 11b Review of form 990 by governing body THE HOWARD HUGHES MEDICAL INSTITUTE'S FORM 990 IS INITIALLY PREPARED BY ITS TAX COMPLIANCE DEPARTMENT, IN COORDINATION WITH OTHER HHMI DEPARTMENTS AS NEEDED. THE DRAFT RETURN IS REVIEWED BY SENIOR MANAGEMENT OF HHMI AND BY ATTORNEYS IN HHMI'S OFFICE OF THE GENERAL COUNSEL. FOLLOWING THESE REVIEWS AND THE RESOLUTION OF ANY QUESTIONS THAT HAVE BEEN RAISED, THE DRAFT RETURN IS REVIEWED BY HHMI'S OUTSIDE TAX PREPARER. FINALLY, A COPY OF THE RETURN IS PROVIDED TO THE MEMBERS OF HHMI'S BOARD OF TRUSTEES SO THAT THEY HAVE AN OPPORTUNITY TO REVIEW AND COMMENT ON THE RETURN BEFORE IT IS FILED.
Form 990, Part VI, Line 12c Conflict of interest policy IN ADDITION TO HHMI'S CODE OF CONDUCT, WHICH ADDRESSES CONFLICTS OF INTEREST AND APPLIES TO ALL HHMI EMPLOYEES, OFFICERS, TRUSTEES, AND ADVISORS, HHMI HAS SPECIFIC CONFLICT OF INTEREST POLICIES FOR DIFFERENT CATEGORIES OF PERSONNEL. UNDER THE HHMI POLICIES THAT APPLY TO TRUSTEES, OFFICERS, AND KEY EMPLOYEES, THESE INDIVIDUALS MUST DISCLOSE ANNUALLY INTERESTS THAT COULD GIVE RISE TO CONFLICTS OF INTEREST, AND MUST CERTIFY ANNUALLY THEIR COMPLIANCE WITH THE CONFLICT OF INTEREST POLICY THAT APPLIES TO THEM. ANNUAL DISCLOSURES AND CERTIFICATIONS ARE REVIEWED BY HHMI'S OFFICE OF THE GENERAL COUNSEL, AND BY OTHER HHMI MANAGERS AS NEEDED. THE CONFLICT OF INTEREST POLICY COVERING HHMI'S TRUSTEES ALSO REQUIRES EACH TRUSTEE TO DISCLOSE TO THE OTHER TRUSTEES ANY ACTUAL OR APPARENT CONFLICT OF INTEREST WITH RESPECT TO A PROPOSED HHMI TRANSACTION. IF THE OTHER TRUSTEES DECIDE THAT THERE IS ONLY THE APPEARANCE OF A CONFLICT OF INTEREST, AND THAT IT COULD NOT REASONABLY BE CONSIDERED TO AFFECT THE INDEPENDENT, UNBIASED JUDGMENT OF THE DISCLOSING TRUSTEE WITH RESPECT TO THE TRANSACTION AT ISSUE, NO FURTHER ACTION IS REQUIRED TO ADDRESS THE APPARENT CONFLICT. IN ALL OTHER CASES, INCLUDING ALL ACTUAL CONFLICTS OF INTEREST, THE DISCLOSING TRUSTEE IS NOT PERMITTED TO PARTICIPATE IN THE DELIBERATION OR DECISION REGARDING THE TRANSACTION UNDER CONSIDERATION, AND MUST LEAVE THE ROOM DURING THE DELIBERATION AND VOTE. THE CONFLICT OF INTEREST POLICIES COVERING HHMI'S OFFICERS AND KEY EMPLOYEES REQUIRE EACH COVERED INDIVIDUAL TO OBTAIN SUPERVISORY APPROVAL UP TO THE LEVEL OF HHMI'S PRESIDENT BEFORE ENTERING INTO AN AFFILIATION WITH OR ACQUIRING AN INTEREST OF 1% OR MORE IN ANY ENTITY THAT IS OR MAY BECOME A RECIPIENT OF HHMI FUNDS. HHMI'S PRESIDENT, IN CONSULTATION WITH HHMI'S GENERAL COUNSEL, MAY PERMIT THE AFFILIATION OR INTEREST IF IT WOULD NOT INTERFERE WITH THE COVERED INDIVIDUAL'S PERFORMANCE OF HIS OR HER HHMI RESPONSIBILITIES, WOULD NOT CREATE THE APPEARANCE OF A CONFLICT OF INTEREST, AND WOULD BE CONSISTENT WITH SOUND BUSINESS JUDGMENT. HHMI'S PRESIDENT MAY SET CONDITIONS ON APPROVAL, FOR EXAMPLE THAT THERE BE NO REMUNERATION TO THE COVERED INDIVIDUAL. PROPOSED AFFILIATIONS AND INTERESTS OF 1% OR MORE OF HHMI'S PRESIDENT ARE SUBJECT TO THE APPROVAL OF THE CHAIRMAN OF THE TRUSTEES.
Form 990, Part VI, Line 15a Process to establish compensation of top management official THE COMPENSATION FOR HHMI'S PRESIDENT, OTHER OFFICERS, AND KEY EMPLOYEES IS SET USING THE FOLLOWING PROCEDURES: EVERY OTHER YEAR, THE AUDIT & COMPENSATION COMMITTEE OF HHMI'S BOARD OF TRUSTEES ENGAGES ONE OR MORE INDEPENDENT COMPENSATION CONSULTANTS TO CONDUCT A STUDY OF COMPARABLE MARKET DATA. THE STUDY INCLUDES DATA FOR HHMI'S PRESIDENT, OTHER OFFICERS, AND KEY EMPLOYEES. THE INDEPENDENT COMPENSATION CONSULTANTS ALSO PROVIDE AN OPINION REGARDING THE REASONABLENESS OF THE COMPENSATION ARRANGEMENTS FOR THE POSITIONS INCLUDED IN THE STUDY. THE STUDY INCLUDES COMPARABLE MARKET DATA FOR ALL COMPONENTS OF COMPENSATION FOR EACH PERSON COVERED BY THE STUDY, INCLUDING BASE SALARY, INCENTIVE COMPENSATION (IF ANY), AND BENEFITS. THE BOARD OF TRUSTEES RELIES ON THE MARKET DATA AND OPINION PROVIDED BY THE COMPENSATION CONSULTANT IN MAKING COMPENSATION DECISIONS FOR HHMI'S PRESIDENT, OTHER OFFICERS, AND KEY EMPLOYEES. THE DECISION IS MADE BY INDEPENDENT TRUSTEES. ANY TRUSTEE WHO HAS A CONFLICT OF INTEREST WITH RESPECT TO A SPECIFIC OFFICER OR KEY EMPLOYEE MUST RECUSE HIMSELF OR HERSELF FROM THE DECISION ON THAT PERSON'S COMPENSATION AND LEAVE THE MEETING ROOM DURING THE DEBATE AND VOTE ON IT. IN THE ALTERNATE YEARS WHEN A STUDY IS NOT DONE, THE TRUSTEES CONFIRM WITH THE INDEPENDENT COMPENSATION CONSULTANTS THAT THE RANGE OF ANY PROPOSED MERIT INCREASES FOR HHMI EMPLOYEES, INCLUDING SENIOR MANAGEMENT, IS REASONABLE COMPARED WITH THE GENERALLY PREVAILING COMPENSATION INCREASES IN THE MARKET OVER THE PAST YEAR. THE BOARD OF TRUSTEES RELIES ON THIS ADVICE IN MAKING COMPENSATION DECISIONS FOR HHMI'S PRESIDENT, OTHER OFFICERS AND KEY EMPLOYEES. RECUSAL PROCEDURES ARE THE SAME AS IN THE YEARS WHEN A STUDY IS DONE. IN EACH YEAR, MINUTES OF THE DISCUSSIONS AND DECISIONS REGARDING COMPENSATION ARE PREPARED AFTER EACH MEETING AND ARE SUBMITTED FOR APPROVAL AT THE NEXT MEETING. APPROVED MINUTES ARE KEPT IN HHMI'S RECORDS. ALL MINUTES INCLUDE THE DATE OF THE MEETING, IDENTIFY THOSE TRUSTEES WHO ATTENDED AND VOTED ON THE COMPENSATION ARRANGEMENTS, AND NOTE ANY RECUSALS OF TRUSTEES WITH A CONFLICT OF INTEREST. THE COMPARABILITY STUDIES AND OPINIONS RELIED ON AT THE MEETING ARE REFERENCED IN THE MINUTES, AND COPIES OF THESE MATERIALS ARE ALSO KEPT IN HHMI'S RECORDS. HHMI'S BOARD OF TRUSTEES FOLLOWED THIS PROCESS IN AUGUST 2022 IN DETERMINING COMPENSATION FOR THE FOLLOWING POSITIONS FOR FISCAL YEAR 2023: PRESIDENT, VICE PRESIDENTS, AND MANAGING DIRECTORS - INVESTMENTS.
Form 990, Part VI, Line 15b Process to establish compensation of other employees THE COMPENSATION FOR HHMI'S PRESIDENT, OTHER OFFICERS, AND KEY EMPLOYEES IS SET USING THE FOLLOWING PROCEDURES: EVERY OTHER YEAR, THE AUDIT & COMPENSATION COMMITTEE OF HHMI'S BOARD OF TRUSTEES ENGAGES ONE OR MORE INDEPENDENT COMPENSATION CONSULTANTS TO CONDUCT A STUDY OF COMPARABLE MARKET DATA. THE STUDY INCLUDES DATA FOR HHMI'S PRESIDENT, OTHER OFFICERS, AND KEY EMPLOYEES. THE INDEPENDENT COMPENSATION CONSULTANTS ALSO PROVIDE AN OPINION REGARDING THE REASONABLENESS OF THE COMPENSATION ARRANGEMENTS FOR THE POSITIONS INCLUDED IN THE STUDY. THE STUDY INCLUDES COMPARABLE MARKET DATA FOR ALL COMPONENTS OF COMPENSATION FOR EACH PERSON COVERED BY THE STUDY, INCLUDING BASE SALARY, INCENTIVE COMPENSATION (IF ANY), AND BENEFITS. THE BOARD OF TRUSTEES RELIES ON THE MARKET DATA AND OPINION PROVIDED BY THE COMPENSATION CONSULTANT IN MAKING COMPENSATION DECISIONS FOR HHMI'S PRESIDENT, OTHER OFFICERS, AND KEY EMPLOYEES. THE DECISION IS MADE BY INDEPENDENT TRUSTEES. ANY TRUSTEE WHO HAS A CONFLICT OF INTEREST WITH RESPECT TO A SPECIFIC OFFICER OR KEY EMPLOYEE MUST RECUSE HIMSELF OR HERSELF FROM THE DECISION ON THAT PERSON'S COMPENSATION AND LEAVE THE MEETING ROOM DURING THE DEBATE AND VOTE ON IT. IN THE ALTERNATE YEARS WHEN A STUDY IS NOT DONE, THE TRUSTEES CONFIRM WITH THE INDEPENDENT COMPENSATION CONSULTANTS THAT THE RANGE OF ANY PROPOSED MERIT INCREASES FOR HHMI EMPLOYEES, INCLUDING SENIOR MANAGEMENT, IS REASONABLE COMPARED WITH THE GENERALLY PREVAILING COMPENSATION INCREASES IN THE MARKET OVER THE PAST YEAR. THE BOARD OF TRUSTEES RELIES ON THIS ADVICE IN MAKING COMPENSATION DECISIONS FOR HHMI'S PRESIDENT, OTHER OFFICERS AND KEY EMPLOYEES. RECUSAL PROCEDURES ARE THE SAME AS IN THE YEARS WHEN A STUDY IS DONE. IN EACH YEAR, MINUTES OF THE DISCUSSIONS AND DECISIONS REGARDING COMPENSATION ARE PREPARED AFTER EACH MEETING AND ARE SUBMITTED FOR APPROVAL AT THE NEXT MEETING. APPROVED MINUTES ARE KEPT IN HHMI'S RECORDS. ALL MINUTES INCLUDE THE DATE OF THE MEETING, IDENTIFY THOSE TRUSTEES WHO ATTENDED AND VOTED ON THE COMPENSATION ARRANGEMENTS, AND NOTE ANY RECUSALS OF TRUSTEES WITH A CONFLICT OF INTEREST. THE COMPARABILITY STUDIES AND OPINIONS RELIED ON AT THE MEETING ARE REFERENCED IN THE MINUTES, AND COPIES OF THESE MATERIALS ARE ALSO KEPT IN HHMI'S RECORDS. HHMI'S BOARD OF TRUSTEES FOLLOWED THIS PROCESS IN AUGUST 2022 IN DETERMINING COMPENSATION FOR THE FOLLOWING POSITIONS FOR FISCAL YEAR 2023: PRESIDENT, VICE PRESIDENTS, AND MANAGING DIRECTORS - INVESTMENTS.
Form 990, Part VI, Line 19 Required documents available to the public HHMI MAKES A COPY OF ITS CHARTER AVAILABLE ON THE HHMI WEBSITE. HHMI'S BY-LAWS ARE AVAILABLE ON REQUEST. HHMI'S CODE OF CONDUCT, WHICH ADDRESSES CONFLICTS OF INTEREST, IS AVAILABLE TO THE PUBLIC ON THE HHMI WEBSITE. A DOWNLOADABLE COPY OF HHMI'S MOST RECENT AUDITED FINANCIAL STATEMENTS IS ALSO AVAILABLE TO THE PUBLIC ON THE WEBSITE.
Form 990, Part VIII, Line 11d Other Miscellaneous Revenue EXTERNAL SHARED RESOURCE REVENUE - Total Revenue: 1890, Related or Exempt Function Revenue: , Unrelated Business Revenue: , Revenue Excluded from Tax Under Sections 512, 513, or 514: 1890; MISCELLANEOUS INCOME - Total Revenue: 13331, Related or Exempt Function Revenue: , Unrelated Business Revenue: , Revenue Excluded from Tax Under Sections 512, 513, or 514: 13331;
Form 990, Part XI, Line 9 Other changes in net assets or fund balances Grant write-offs - 655158; Grant refunds - 940856; Other components of net periodic benefit cost - XXX-XX-XXXX;
Schedule A, Part I, Line 4 List of Hospital Affiliations List of hospital affiliations for e-filing: Hospital, City, State, Zip Code - Brigham & Women's Hospital, Boston, MA 02115/ Baylor affil hosps, Houston, TX 77030/ Beth Israel Deaconess Med Ctr, Boston, MA 02215/ Brandeis affil hosps, Waltham, MA 02254/ CalTech affil hosps, Pasadena, CA 91125/ Carnegie affil hosp, Baltimore, MD 21218/ Boston Children's Hosp, Boston, MA 02115/ Columbia affil hosps, New York, NY 10027/ Cornell affil hosp, New York, NY 14853/ CSHL affil hosps, Cold Spring Harbor, NY 11724/ Dana-Farber Cancer Inst, Boston, MA 02115/ Duke affil hosps, Durham, NC 27706/ Fred Hutchinson affil hosp, Seattle, WA 98109/ Harvard affil hosps, Cambridge, MA 02138/ Icahn School of Med affil hosp, New York, NY 10029/ Indiana Univ affil hosp, Bloomington, IN 47405/ Johns Hopkins Hosp, Baltimore, MD 21205/ JHU affil hosps, Baltimore, MD 21218/ Mass Gen Hosp, Boston, MA 02129/ MIT affil hosps, Boston, MA 02139/ MSKCC affil hosps, New York, NY 10021/ Northwestern Univ affil hosps, Evanston, IL 60208/ NYU affil hosps, New York, NY 10016/ OHSU Hosp, Portland, OR 97239/ Princeton affil hosps, Princeton, NJ 08544/ PSU affil hosps, State College, PA 16802/ Rockefeller Hosp, New York, NY 10021/ Salk Institute affil hosps, La Jolla, CA 92093/ Scripps Institute affil hosps, La Jolla, CA 92037/ St. Jude Children's Research Hosp, Memphis, TN 38105/ Stanford affil hosps, Palo Alto, CA 94305/ Stowers Institute affil hosps, Kansas City, MO 64110/ UC Berkeley affil hosps, Berkeley, CA 94720/ UC Davis affil hosp, Davis, CA 95616/ Univ of Chicago affil hosp, Chicago, IL 60637/ UCLA Med Ctr affil hosps, Los Angeles, CA 90095/ Univ of Colorado affil hosp, Boulder, CO 80309/ Univ of Colorado affil hosp, Denver, CO 80204/ UC Santa Cruz affil hosps, Santa Cruz, CA 95064/ UC San Diego affil hosps, San Diego, CA 92093/ UCSF affil hosps, San Francisco, CA 94143/ Univ of Illinois affil hosp, Urbana, IL 61801/ Univ of Iowa affil hosps, Iowa City, IA 52242/ UMass Med Ctr, Worcester, MA 01605/ UMD Baltimore County affil hosp, Baltimore, MD 21201/ UMD College Park affil hosp, College Park, MD 20742/ Univ of Michigan Hosps, Ann Arbor, MI 48109/ Univ of Minnesota affil hosps, Minneapolis, MN 55414/ UNC affil hosps, Chapel Hill, NC 27599/ Univ of Oregon affil hosp, Eugene, OR 97403/ UPenn affil hosps, Philadelphia, PA 19104/ UT Austin affil hosps, Austin, TX 78712/ UT Health Sci Ctr San Antonio, San Antonio, TX 78229/ UTSW Med Ctr affil hosp, Dallas, TX 75390/ Univ of Utah affil hosps, Salt Lake City, UT 84112/ Univ of Virginia affil hosps, Charlottesville, VA 22903/ Univ of Wash Med Ctr, Seattle, WA 98195/ Univ of Wisconsin affil hosps, Madison, WI 53706/ Whitehead affil hosps, Cambridge, MA 02138/ Yale affil hosp, New Haven, CT 06520
Schedule A, Part I, Line 4 MRO Qualification The Institute is a medical research organization for its taxable year ended August 31, 2022, as its expenditures of $855,939,253 on a cash basis for the year ended August 31, 2021 exceeded the MRO requirement of $838,082,904 (3.5% of the HHMI endowment).
For Paperwork Reduction Act Notice, see the Instructions for Form 990 or 990-EZ.
Cat. No. 51056K
Schedule O (Form 990) 2021


Additional Data


Software ID: 21014044
Software Version: 2021v4.2
SCHEDULE R
(Form 990)

Department of the Treasury
Internal Revenue Service
Related Organizations and Unrelated Partnerships
MediumBulletComplete if the organization answered "Yes" on Form 990, Part IV, line 33, 34, 35b, 36, or 37.
MediumBulletAttach to Form 990.
MediumBullet Go to www.irs.gov/Form990 for instructions and the latest information.

OMB No. 1545-0047
2021
Open to Public Inspection
Name of the organization
Howard Hughes Medical Institute
 
Employer identification number

59-0735717
Part I
Identification of Disregarded Entities. Complete if the organization answered "Yes" on Form 990, Part IV, line 33.
(a)
Name, address, and EIN (if applicable) of disregarded entity


(b)
Primary activity


(c)
Legal domicile (state
or foreign country)

(d)
Total income


(e)
End-of-year assets


(f)
Direct controlling
entity

(1) HHMI I LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT DE     HHMI
 
(2) HHMI II LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT DE 15,665,379 9,678 HHMI
 
(3) HHMI III LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT DE     HHMI
 
(4) HHMI IV LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT DE     HHMI
 
(5) HHMI V LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT DE     HHMI
 
(6) HHMI VI LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT DE     HHMI
 
(7) HHMI VII LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT DE 1,094,620 40,351,516 HHMI
 
(8) HHMI VIII LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT DE     HHMI
 
(9) HHMI XII LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT DE     HHMI
 
(10) HHMI XIII LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT DE     HHMI
 
(11) HHMI XIV LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT DE     HHMI
 
(12) HHMI XV LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT DE     HHMI
 
(13) HHMI-SA LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
RESEARCH DE     HHMI
 
(14) JANELIA FARM HOLDING LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT VA -253,074   HHMI
 
(15) LSV ADVANTAGE INTERNATIONAL III LLC
540 MADISON AVENUE 33RD FL
New York,NY10022
INVESTMENT DE -32,756 4,733,766 HHMI
 
(16) LSV ADVANTAGE INTERNATIONAL III-B LLC
540 MADISON AVENUE 33RD FL
New York,NY10022
INVESTMENT DE 15,497,985 93,071,182 HHMI
 
(17) LSV ADVANTAGE INTL III (CAYMAN) LTD
89 NEXUS WAY 2/F CAMANA BAY
  GRAND CAYMANKY11205
CJ
98-0689621
INVESTMENT CJ -25,330 2,254,284 HHMI
 
(18) LSV ADVANTAGE INTL III-B (CAYMAN) LTD
89 NEXUS WAY 2/F CAMANA BAY
  GRAND CAYMANKY11205
CJ
98-1087158
INVESTMENT CJ 11,147,910 23,068,619 HHMI
 
(19) MISSING LINK PRODUCTIONS LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
47-1329820
FILM PROD DE   2,627 HHMI
 
(20) PSG LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT DE     HHMI
 
(21) SELDEN ISLAND HOLDING LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT VA     HHMI
 
(22) SPRUGOS INVESTMENTS II LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT DE     HHMI
 
(23) SPRUGOS INVESTMENTS III LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT DE 1,224,951 287,170,770 HHMI
 
(24) SPRUGOS INVESTMENTS IX LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT DE     HHMI
 
(25) SPRUGOS INVESTMENTS V LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT DE     HHMI
 
(26) SPRUGOS INVESTMENTS VI LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT DE     HHMI
 
(27) SPRUGOS INVESTMENTS VII LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT DE 33,386,505 340,361 HHMI
 
(28) SPRUGOS INVESTMENTS VIII LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT DE 320,622 204,602,477 HHMI
 
(29) SPRUGOS INVESTMENTS X LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT DE     HHMI
 
(30) SPRUGOS INVESTMENTS XI LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT DE -8,947,743   HHMI
 
(31) SPRUGOS INVESTMENTS XII LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
INVESTMENT DE     HHMI
 
(32) TANGLED BANK STUDIOS LLC
4000 JONES BRIDGE ROAD
CHEVY CHASE,MD20815
FILM PROD DE 1,162,470   HHMI
 
Part II
Identification of Related Tax-Exempt Organizations. Complete if the organization answered "Yes" on Form 990, Part IV, line 34 because it had one or more related tax-exempt organizations during the tax year.
(a)
Name, address, and EIN of related organization


(b)
Primary activity


(c)
Legal domicile (state
or foreign country)

(d)
Exempt Code section


(e)
Public charity status
(if section 501(c)(3))

(f)
Direct controlling
entity

(g)
Section 512(b)(13) controlled entity?
Yes No












For Paperwork Reduction Act Notice, see the Instructions for Form 990.
Cat. No. 50135Y
Schedule R (Form 990) 2021
Schedule R (Form 990) 2021
Page 2
Part III
Identification of Related Organizations Taxable as a Partnership. Complete if the organization answered "Yes" on Form 990, Part IV, line 34, because it had one or more related organizations treated as a partnership during the tax year.
(a)
Name, address, and EIN of
related organization



(b)
Primary activity




(c)
Legal
domicile
(state or foreign
country)


(d)
Direct controlling
entity



(e)
Predominant income(related, unrelated, excluded from tax under sections 512-514)

(f)
Share of total income




(g)
Share of end-of-year
assets



(h)
Disproprtionate allocations?




(i)
Code V-UBI
amount in box 20 of
Schedule K-1
(Form 1065)
(j)
General or
managing
partner?



(k)
Percentage
ownership


Yes No Yes No
(1) AGHAP FEEDER LLC

601 CARLSON PKWY STE 200
MINNETONKA,MN55305
82-2892485
INVESTMENT DE HHMI
 
Excluded 22,293,368 1,165,146   No 1,553,823   No 0 %
(2) APCM OPPORTUNITY FUND LP

530 FIFTH AVENUE 20TH FLOOR
NEW YORK,NY10036
84-1808166
INVESTMENT DE HHMI
 
Excluded 2,801,352 101,556,416   No     No 99 %
(3) BLOSSOM CAPITAL CO-INVESTMENT (CH) LP

 
 
INVESTMENT GK HHMI
 
Excluded 0 0   No     No 62 %
(4) BLOSSOM CAPITAL CO-INVESTMENT (MP) LP

 
 
INVESTMENT GK HHMI
 
Excluded -79,114 30,070,759   No     No 50 %
(5) BLOSSOM CAPITAL CO-INVESTMENT (P1) LP

 
 
INVESTMENT GK HHMI
 
Excluded 0 0   No     No 100 %
(6) BLOSSOM CAPITAL CO-INVESTMENT (T1) LP

 
 
INVESTMENT GK HHMI
 
Excluded 0 0   No     No 100 %
(7) BROWNING WEST SPV 3 LP

WALKERS CORPORATE
27 HOSPITAL ROAD
GEORGE TOWN,GRAND CAYMANKY19009
CJ
86-2097815
INVESTMENT DE HHMI
 
Excluded 321,061 50,289,701   No     No 68 %
(8) CERBERUS HH PARTNERS AIV LP

ONE NEXUS WAY
CAMANA BAY,GRAND CAYMANKY19005
CJ
85-4216473
INVESTMENT CJ HHMI
 
Excluded 720,296 4,253,887   No     No 85 %
(9) CERBERUS HH PARTNERS LP

ONE NEXUS WAY
CAMANA BAY,GRAND CAYMANKY19005
CJ
98-1102879
INVESTMENT CJ HHMI
 
Excluded 4,811,204 21,885,530   No     No 83 %
(10) DARK ROAST CAPITAL LP

130 W 42ND ST 20TH FL
NEW YORK,NY10036
84-3603822
INVESTMENT DE HHMI
 
Excluded 1,378,753 29,601,855   No     No 60 %
(11) DCVR HM STRATEGIC PARTNERS LP (FKA COLHM STRATEGIC PARTNERS LP)

515 SOUTH FLOWER ST 44TH FL
LOS ANGELES,CA90071
45-3436140
INVESTMENT CA HHMI
 
Excluded 1,022 25,852,285   No     No 100 %
(12) DIAKRISIS FUND LP

2777 SUMMER STREET SUITE 301
STAMFORD,CT06905
35-2577920
INVESTMENT CT HHMI
 
Excluded 19,624,242 243,773,632   No     No 69 %
(13) ECHO STREET CAPITAL CV 1 LLC

251 LITTLE FALLS DRIVE
WILMINGTON,DE19808
35-2577921
INVESTMENT DE HHMI
 
Excluded 0 8,075,005   No     No 100 %
(14) ELLINGTON SYSTEMATIC MASTER FUND LTD FKA HH ELLINGTON MASTER FUND LTD

WALKER HOUSE 87 MARY ST
GEORGE TOWN,GRAND CAYMANKY11104
CJ
98-1020904
INVESTMENT CJ HH ELLINGTON SYSTEMATIC CREDIT FUND LTD
 
Excluded 23,994,711 490,521,825   No     No 94 %
(15) EMMA 1 MASTER FUND LP

411 WEST PUTNAM AVENUE
GREENWICH,CT06830
98-1500184
INVESTMENT CJ EMMA 1 FEEDER FUND LTD
 
Excluded 16,735,225 202,570,058   No     No 100 %
(16) ENDEAVOR CAPITAL PRIVATE INVESTMENTS I LP

410 GREENWICH AVENUE
GREENWICH,CT06830
82-3123572
INVESTMENT CT HHMI
 
Excluded 7,537,899 103,033,038   No     No 70 %
(17) FINANCIAL HYBRID OPPORTUNITY SPV I LLC

1313 DOLLEY MADISON BLVD
SUITE 306
MCLEAN,VA22101
82-5280920
INVESTMENT VA HHMI
 
Excluded 2,943,501 92,396,995   No     No 98 %
(18) GEM BVP CO-INV-A LP

900 NORTH MICHIGAN AVENUE
SUITE 1450
CHICAGO,IL60611
47-2251559
INVESTMENT IL HHMI
 
Excluded 0 4,459,857   No     No 100 %
(19) HH ELLINGTON MASTER FUND II LTD

WALKER HOUSE 87 MARY ST
GEORGE TOWN,GRAND CAYMANKY11104
CJ
98-1416628
INVESTMENT CJ HH ELLINGTON FUND II LTD
 
Excluded 0 0   No     No 0 %
(20) HH HOLDCO CO-INVESTMENT FUND LP

32 BROADWAY SUITE 1201
NEW YORK,NY10017
30-0864915
INVESTMENT NY HHMI
 
Excluded 94,784 2,574,878   No     No 90 %
(21) IG4 CAPITAL PRIVATE EQUITY INVESTMENTS II-C LP

 
 
INVESTMENT JE HHMI
 
Excluded 4,471 51,263,485   No     No 88 %
(22) IG4 CAPITAL INFRASTRUCTURE CO-INVESTMENTS A LP

 
 
INVESTMENT JE HHMI
 
Excluded 20,859 22,849,962   No     No 80 %
(23) IG4 CAPITAL INFRASTRUCTURE CO-INVESTMENTS B1 LP

 
 
INVESTMENT JE HHMI
 
Excluded 466 5,585,760   No     No 81 %
(24) IG4 CAPITAL INFRASTRUCTURE CO-INVESTMENTS B2 LP

 
 
INVESTMENT JE HHMI
 
Excluded 466 5,585,760   No     No 81 %
(25) IG4 CAPITAL INFRASTRUCTURE CO-INVESTMENTS B3 LP

 
 
INVESTMENT JE HHMI
 
Excluded 466 5,585,760   No     No 81 %
(26) IG4 CAPITAL PRIVATE EQUITY INVESTMENTS II-A LP

 
 
INVESTMENT JE HHMI
 
Excluded 4,471 51,263,485   No     No 88 %
(27) IG4 CAPITAL PRIVATE EQUITY INVESTMENTS II-B LP

 
 
INVESTMENT JE HHMI
 
Excluded 4,471 51,263,485   No     No 88 %
(28) MADISON ACQUISITION 4 LP

540 MADISON AVENUE 33RD FL
NEW YORK,NY10022
36-4705548
INVESTMENT DE LSV ADVANTAGE INTERNATIONAL III-B LLC
 
Excluded 1,267,375 5,637,435   No     No 66 %
(29) MONARCH SPECIAL OPPORTUNITIES MASTER FUND LTD

 
 
INVESTMENT CJ MSOF HOLDINGS LTD
 
Excluded 80,845,775 143,741,286   No     No 95 %
(30) MSOF HOLDINGS LTD

 
 
INVESTMENT CJ MONARCH SPECIAL OPPORTUNITIES FUND LTD
 
Excluded 80,845,775 143,741,286   No     No 100 %
(31) PRISMA CAPITAL SPECIAL SITUTATIONS FUND I C LP

C/O 152928 CANADA INC 199 BAY ST
5300 COMMERCE COURT WEST
TORONTO,ONTARIOM5L1B9
CA
98-1468087
INVESTMENT CA PRISMA CAPITAL SPECIAL SITUATIONS FEEDER I LP
 
Excluded 5,878,811 40,445,412   No     No 57 %
(32) PSSI CO-INVESTMENT 1 LP

 
 
98-1492831
INVESTMENT CA HHMI
 
Excluded 7,458,880 3,547,505   No     No 75 %
(33) PSSI COINVESTMENT 3 LP

 
 
98-1536870
INVESTMENT CA PSSI COINVESTMENT 3 FEEDER LP
 
Excluded -832,712 20,161,016   No     No 100 %
(34) QED SOL HOLDINGS LLC

251 LITTLE FALLS DRIVE
WILMINGTON,DE19808
INVESTMENT DE HHMI
 
Excluded 0 0   No     No 53 %
(35) RCH OIL AND GAS MIDSTREAM FUND

3953 MAPLE AVENUE
SUITE 180
DALLAS,TX75219
83-1010065
INVESTMENT TX HHMI
 
Excluded 42,085,547 122,347,788   No     No 100 %
(36) SERENGETI MULTI-SERIES INTERMEDIATE LLC SERIES HH

2 BLOOR STREET EAST
SUITE 2700
TORONTO,ONTARIOM4W1A8
CA
INVESTMENT DE SERENGETI SEGREGATED PORTFOLIO COMPANY LTD PORTFOLIO HH
 
Excluded -15,831,975 0   No     No 0 %
(37) SERENGETI MULTI-SERIES MASTER LLC SERIES HH

2 BLOOR STREET EAST
SUITE 2700
TORONTO,ONTARIOM4W1A8
CA
INVESTMENT DE SERENGETI SEGREGATED PORTFOLIO COMPANY LTD PORTFOLIO HH
 
Excluded -15,831,975 0   No     No 0 %
(38) SOLUS OPPORTUNITIES FUND 2 LP

410 PARK AVENUE 11TH FLOOR
NEW YORK,NY10022
46-3541945
INVESTMENT NY HHMI
 
Excluded -124 19,930,556   No     No 88 %
Part IV
Identification of Related Organizations Taxable as a Corporation or Trust. Complete if the organization answered "Yes" on Form 990, Part IV, line 34 because it had one or more related organizations treated as a corporation or trust during the tax year.
(a)
Name, address, and EIN of
related organization
(b)
Primary activity
(c)
Legal
domicile
(state or foreign
country)
(d)
Direct controlling
entity
(e)
Type of entity
(C corp, S corp,
or trust)
(f)
Share of total income
(g)
Share of end-of-year
assets
(h)
Percentage
ownership
(i)
Section 512(b)(13) controlled entity?
Yes No
(1) 37 CAPITAL BLUESCALE FUND LTD

100 FEDERAL STREET
BOSTON,MA02110
INVESTMENT CJ HHMI
 
C Corporation 9,833,385 0 0 % Yes  
(2) BLANTYRE MULANJE SPC

PO BOX 309 UGLAND HOUSE
GEORGE TOWN,GRAND CAYMANKY11104
CJ
INVESTMENT CJ HHMI
 
C Corporation 2,164,472 18,162,957 61 % Yes  
(3) BLANTYRE SPECIAL SITUATIONS FUND I LIMITED

PO BOX 309 UGLAND HOUSE
GEORGE TOWN,GRAND CAYMANKY11104
CJ
INVESTMENT CJ HHMI
 
C Corporation 4,202,475 129,836,983 68 % Yes  
(4) BLANTYRE SPECIAL SITUATIONS FUND II LIMITED

PO BOX 309 UGLAND HOUSE
GEORGE TOWN,GRAND CAYMANKY11104
CJ
INVESTMENT CJ HHMI
 
C Corporation -266,267 98,178,121 81 % Yes  
(5) BRIARWOOD CAPITAL (OFFSHORE) LTD

130 W 42ND ST
20TH FLOOR
NEW YORK,NY10036
INVESTMENT CJ HHMI
 
C Corporation 2,575,299 124,136,617 86 % Yes  
(6) EJF IB FINANCING LP

WALKERS CORPORATE
27 HOSPITAL ROAD
GEORGE TOWN,GRAND CAYMANKY19008
CJ
98-1293036
INVESTMENT CJ HHMI
 
C Corporation 666,600 11,306,297 100 % Yes  
(7) ELLINGTON SYSTEMATIC CREDIT FUND LTD (FKA HH ELLINGTON FUND LTD)

WALKER HOUSE 87 MARY STREET
GEORGE TOWN,GRAND CAYMANKY11104
CJ
INVESTMENT CJ HHMI
 
C Corporation 23,728,073 146,332,640 100 % Yes  
(8) EMMA 1 FEEDER FUND LTD

89 NEXUS WAY CAMANA BAY
GEORGE TOWN,GRAND CAYMANKY11205
CJ
98-1500792
INVESTMENT CJ HHMI
 
C Corporation 16,734,986 171,996,047 100 % Yes  
(9) EPIRIS FUND II CO-INVESTMENT (B) 2 LP

 
 
98-1466593
INVESTMENT JE HHMI
 
C Corporation 70,392 12,093,767 89 % Yes  
(10) HH ELLINGTON FUND II LTD

WALKER HOUSE 87 MARY STREET
GEORGE TOWN,GRAND CAYMANKY11104
CJ
98-1416785
INVESTMENT CJ HHMI
 
C Corporation 37,314,504 0 0 % Yes  
(11) LSV ADVANTAGE INTERNATIONAL III LTD

89 NEXUS WAY 2/F CAMANA BAY
GEORGE TOWN,GRAND CAYMANKY11205
CJ
98-1300995
INVESTMENT CJ HHMI
 
C Corporation 0 683,105 100 % Yes  
(12) LSV ADVANTAGE INTERNATIONAL III-B LTD

89 NEXUS WAY 2/F CAMANA BAY
GEORGE TOWN,GRAND CAYMANKY11205
CJ
98-1315328
INVESTMENT CJ HHMI
 
C Corporation 170,597 15,440,150 100 % Yes  
(13) LSV ADVANTAGE INTERNATIONAL III-C LTD

89 NEXUS WAY 2/F CAMANA BAY
GEORGE TOWN,GRAND CAYMANKY11205
CJ
98-1331158
INVESTMENT CJ HHMI
 
C Corporation 4,013,165 29,964,274 100 % Yes  
(14) MONARCH SPECIAL OPPORTUNITIES FUND LTD

 
 
INVESTMENT CJ HHMI
 
C Corporation 80,848,968 143,741,286 100 % Yes  
(15) NEWFOUNDLAND TERRANOVA OFFSHORE FUND

89 NEXUS WAY CAMANA BAY
GEORGE TOWN,GRAND CAYMANKY19007
CJ
INVESTMENT CJ HHMI
 
C Corporation 2,616,168 218,858,304 97 % Yes  
(16) PORTSEA FUND SICAV PLC

 
 
INVESTMENT MT HHMI
 
C Corporation 1,491,120 154,640,548 69 % Yes  
(17) PRISMA CAPITAL SOLUTIONS FUND II FEEDER LP

199 BAY ST 5300 COMMERCE COURT WES
TORONTO,ONTARIOM5L1B9
CA
INVESTMENT CA HHMI
 
C Corporation 0 0 89 % Yes  
(18) PRISMA CAPITAL SPECIAL SITUATIONS FEEDER I LP

199 BAY ST 5300 COMMERCE COURT WES
TORONTO,ONTARIOM5L1B9
CA
98-1492831
INVESTMENT CA HHMI
 
C Corporation 2,789,011 65,342,430 100 % Yes  
(19) PSSI COINVESTMENT 3 FEEDER LP

 
 
98-1552419
INVESTMENT CA HHMI
 
C Corporation 2,141,174 19,440,728 100 % Yes  
(20) SERENGETI SEGREGATED PORTFOLIO COMPANY LTD PORTFOLIO HH

2 BLOOR STREET EAST STE 2700
TORONTO,ONTARIOM4W1A8
CA
INVESTMENT CJ HHMI
 
C Corporation -16,274,962 0 0 % Yes  
(21) SPECIAL SITUATIONS HH CARRY LP

PO BOX 309 UGLAND HOUSE
GEORGE TOWN,GRAND CAYMANKY11104
CJ
98-1513197
INVESTMENT CJ HHMI
 
C Corporation 0 3,300,149 100 % Yes  
(22) SQN INVESTORS OFFSHORE LTD

 
 
INVESTMENT CJ HHMI
 
C Corporation 56,785,777 259,753,081 67 % Yes  
(23) STAR ASIA JAPAN SPECIAL SITUATIONS III FEEDER LP

125 GAITHER DR STE L
MOUNT LAUREL,NJ08054
61-1892450
INVESTMENT CJ HHMI
 
C Corporation 478,127 69,781 0 % Yes  
(24) STAR ASIA JAPAN SPECIAL SITUATIONS IV FEEDER LP

125 GAITHER DR STE L
MOUNT LAUREL,NJ08054
98-1520753
INVESTMENT CJ HHMI
 
C Corporation 12,506,166 126,306,907 100 % Yes  
(25) STAR ASIA JAPAN SPECIAL SITUATIONS V FEEDER LP

125 GAITHER DR STE L
MOUNT LAUREL,NJ08054
98-1568847
INVESTMENT CJ HHMI
 
C Corporation 14,928,407 40,093,314 100 % Yes  
(26) WILLA A LP

 
 
98-1380677
INVESTMENT JE HHMI
 
C Corporation 8,745,373 22,440,004 100 % Yes  
Schedule R (Form 990) 2021
Schedule R (Form 990) 2021
Page 3
Part V
Transactions With Related Organizations. Complete if the organization answered "Yes" on Form 990, Part IV, line 34, 35b, or 36.
Note. Complete line 1 if any entity is listed in Parts II, III, or IV of this schedule.
Yes
No
1 During the tax year, did the orgranization engage in any of the following transactions with one or more related organizations listed in Parts II-IV?
a Receipt of (i) interest, (ii) annuities, (iii) royalties, or (iv) rent from a controlled entity .....................
1a
 
No
b Gift, grant, or capital contribution to related organization(s) ............................
1b
Yes
 
c Gift, grant, or capital contribution from related organization(s) ............................
1c
 
No
d Loans or loan guarantees to or for related organization(s) ............................
1d
 
No
e Loans or loan guarantees by related organization(s) ............................
1e
 
No
f Dividends from related organization(s) ............................
1f
 
No
g Sale of assets to related organization(s) ............................
1g
 
No
h Purchase of assets from related organization(s) ............................
1h
 
No
i Exchange of assets with related organization(s) ............................
1i
 
No
j Lease of facilities, equipment, or other assets to related organization(s) .......................
1j
 
No
k Lease of facilities, equipment, or other assets from related organization(s) ......................
1k
 
No
l Performance of services or membership or fundraising solicitations for related organization(s) .....................
1l
 
No
m Performance of services or membership or fundraising solicitations by related organization(s) .................
1m
 
No
n Sharing of facilities, equipment, mailing lists, or other assets with related organization(s) ...................
1n
 
No
o Sharing of paid employees with related organization(s) ............................
1o
 
No
p Reimbursement paid to related organization(s) for expenses ............................
1p
 
No
q Reimbursement paid by related organization(s) for expenses ............................
1q
 
No
r Other transfer of cash or property to related organization(s) ............................
1r
 
No
s Other transfer of cash or property from related organization(s) ............................
1s
Yes
 
2
If the answer to any of the above is "Yes," see the instructions for information on who must complete this line, including covered relationships and transaction thresholds.
(a)
Name of related organization
(b)
Transaction
type (a-s)
(c)
Amount involved
(d)
Method of determining amount involved
(1) 37 Capital Bluescale Fund Ltd

S 113,030,555 FMV
(2) AGHAP Feeder LLC

S 21,404,586 FMV
(3) APCM OPPORTUNITY FUND LP

S 850,000 FMV
(4) Blantyre Mulanje SPC

S 8,413,202 FMV
(5) Blantyre Special Situations Fund I Limited

S 22,225,689 FMV
(6) Blantyre Special Situations Fund II Limited

B 97,261,499 FMV
(7) Blossom Capital Co-Investment (CH) LP

B 16,617,284 FMV
(8) Blossom Capital Co-Investment (MP) LP

B 15,075,000 FMV
(9) Blossom Capital Co-Investment (P1) LP

B 10,060,000 FMV
(10) Blossom Capital Co-Investment (T1) LP

B 10,026,019 FMV
(11) Briarwood Capital (Offshore) Ltd

S 28,630,272 FMV
(12) Briarwood Capital (Offshore) Ltd

B 84,630,272 FMV
(13) Cerberus HH Partners LP

S 9,581,058 FMV
(14) Dark Roast Capital LP

B 5,000,000 FMV
(15) Diakrisis Fund LP

B 104,000,000 FMV
(16) Echo Street Capital CV 1 LLC

B 8,000,000 FMV
(17) EJF IB Financing

S 3,017,891 FMV
(18) Endeavour Capital Private Investments I LP

S 7,387,443 FMV
(19) Epiris Fund II Co-Investment (B) 2 LP

S 751,276 FMV
(20) Financial Hybrid Opportunity SPV I LLC

S 10,965,035 FMV
(21) GEM BVP CO-INV-A

B 925,000 FMV
(22) HH Ellington Fund II Ltd

S 26,219,087 FMV
(23) HH Holdco Co-Investment Fund LP

B 202,334 FMV
(24) HH Holdco Co-Investment Fund LP

S 971,334 FMV
(25) IG4 Capital Infrastructure Co-Investments A LP

S 238,006 FMV
(26) IG4 Capital Infrastructure Co-Investments A LP

B 8,510,000 FMV
(27) IG4 CAPITAL PRIVATE EQUITY INVESTMENTS II-A LP

S 7,642,341 FMV
(28) IG4 CAPITAL PRIVATE EQUITY INVESTMENTS II-A LP

B 14,930,362 FMV
(29) IG4 CAPITAL PRIVATE EQUITY INVESTMENTS II-B LP

S 7,642,341 FMV
(30) IG4 CAPITAL PRIVATE EQUITY INVESTMENTS II-B LP

B 14,930,362 FMV
(31) IG4 CAPITAL PRIVATE EQUITY INVESTMENTS II-C LP

S 7,642,341 FMV
(32) IG4 CAPITAL PRIVATE EQUITY INVESTMENTS II-C LP

B 14,930,362 FMV
(33) LSV Advantage International III-B Ltd

B 155,220 FMV
(34) LSV Advantage International III-B Ltd

S 1,222,016 FMV
(35) LSV Advantage International III-C Ltd

B 277,669 FMV
(36) LSV Advantage International III-C Ltd

S 9,143,923 FMV
(37) Madison Acquisition 4 LP

B 88,250 FMV
(38) Madison Acquisition 4 LP

S 706,054 FMV
(39) Monarch Special Opportunities Fund Ltd - Series A Series B

S 91,222,198 FMV
(40) Newfoundland Terra Nova Offshore Fund

B 11,048,668 FMV
(41) Newfoundland Terra Nova Offshore Fund

S 31,000,000 FMV
(42) Portsea Fund SICAV PLC

S 109,687,745 FMV
(43) Prisma Capital Solutions Fund II Feeder LP

B 7,189,372 FMV
(44) Prisma Capital Special Situations Feeder I LP

B 17,266,326 FMV
(45) Prisma Capital Special Situations Feeder I LP

S 15,613,669 FMV
(46) PSSI Co-Investment 1 LP

S 434,126 FMV
(47) PSSI Co-Investment 3 Feeder LP

B 19,343,401 FMV
(48) PSSI Co-Investment 3 Feeder LP

S 19,526,347 FMV
(49) QED Sol Holdings LLC

B 13,250,000 FMV
(50) Serengeti Multi-Series Intermediate LLC

S 2,794,613 FMV
(51) Star Asia Japan Special Situations IV Feeder LP

B 6,793,687 FMV
(52) Star Asia Japan Special Situations IV Feeder LP

S 10,256,524 FMV
(53) Star Asia Japan Special Situations V Feeder LP

B 12,041,179 FMV
Schedule R (Form 990) 2021
Schedule R (Form 990) 2021
Page 4
Part VI
Unrelated Organizations Taxable as a Partnership. Complete if the organization answered "Yes" on Form 990, Part IV, line 37.
Provide the following information for each entity taxed as a partnership through which the organization conducted more than five percent of its activities (measured by total assets or gross revenue) that was not a related organization. See instructions regarding exclusion for certain investment partnerships.
(a)
Name, address, and EIN of entity
(b)
Primary activity
(c)
Legal domicile
(state or foreign
country)
(d)
Predominant income (related, unrelated, excluded from tax under sections 512-514)

(e)
Are all partners
section
501(c)(3)
organizations?
(f)
Share of total income




(g)
Share of
end-of-year
assets
(h)
Disproprtionate allocations?
(i)
Code V-UBI
amount in box 20
of Schedule K-1
(Form 1065)
(j)
General or
managing
partner?
(k)
Percentage
ownership


Yes No Yes No Yes No






























Schedule R (Form 990) 2021
Schedule R (Form 990) 2021
Page 5
Part VII
Supplemental Information
Provide additional information for responses to questions on Schedule R. See instructions.
Return Reference Explanation
Schedule R (Form 990) 2021

Additional Data


Software ID: 21014044
Software Version: 2021v4.2