TIN:
SCHEDULE O
(Form 990)
Department of the Treasury
Internal Revenue Service
(Form 990)
Department of the Treasury
Internal Revenue Service
Supplemental Information to Form 990 or 990-EZ
Complete to provide information for responses to specific questions on
Form 990 or 990-EZ or to provide any additional information.
Attach to Form 990 or 990-EZ.
Go to www.irs.gov/Form990 for the latest information.
OMB No. 1545-0047
2021
Open to Public
Inspection
Inspection
Name of the organization
THE BROAD INSTITUTE INC
Employer identification number
26-3428781
26-3428781
| Return Reference | Explanation |
|---|---|
| ORGANIZATION'S MISSION | FORM 990, PART I, LINE 1 THE MISSION OF THE BROAD INSTITUTE IS TO PROPEL PROGRESS IN BIOMEDICINE, THROUGH RESEARCH AIMED AT THE UNDERSTANDING AND TREATMENT OF DISEASE, AND THE DISSEMINATION OF SCIENTIFIC KNOWLEDGE TO THE SCIENTIFIC COMMUNITY TO BENEFIT THE PUBLIC. WE ARE A RESEARCH ORGANIZATION DEDICATED TO BETTER UNDERSTANDING THE ROOTS OF DISEASE AND NARROWING THE GAP BETWEEN NEW BIOLOGICAL INSIGHTS AND IMPACT FOR PATIENTS. |
| VOLUNTEERS | FORM 990, PART I, LINE 6 THE BROAD INSTITUTE DOES NOT FORMALLY TRACK VOLUNTEERS BUT HAS INCLUDED THE NUMBER OF BOARD MEMBERS AND COMMITTEE MEMBERS THAT ARE UNCOMPENSATED. |
| STATEMENT OF PROGRAM SERVICE ACCOMPLISHMENTS | FORM 990, PART III, LINE 4A THE BROAD INSTITUTE OPERATES FOR EDUCATIONAL AND SCIENTIFIC PURPOSES TO IMPROVE HUMAN HEALTH BY USING GENOMICS TO ADVANCE THE UNDERSTANDING OF THE BIOLOGY AND TREATMENT OF HUMAN DISEASE, AND TO HELP LAY THE GROUNDWORK FOR A NEW GENERATION OF THERAPIES. THE INSTITUTE DEFINES A NEW COLLABORATIVE MODEL FOR BIOMEDICAL RESEARCH, BRINGING TOGETHER EXTRAORDINARY SCIENTISTS ACROSS HARVARD, MIT AND HARVARD-AFFILIATED HOSPITALS AND USES NEW APPROACHES THAT COMBINE BIOLOGY, CHEMISTRY, MATHEMATICS, COMPUTATION AND ENGINEERING WITH MEDICAL SCIENCE AND CLINICAL RESEARCH. ITS SCIENTISTS ARE COMMITTED TO UNDERSTANDING THE FUNDAMENTAL BASIS OF GENOME AND CELL BIOLOGY, AND TO DEVELOPING TRANSFORMATIVE NEW APPROACHES TO BIOMEDICAL RESEARCH. SCIENTIFIC AREAS INCLUDE CHEMICAL BIOLOGY AND THERAPEUTICS SCIENCE, DRUG DISCOVERY, GENOME REGULATION, CELLULAR CIRCUITRY AND EPIGENOMICS, IMMUNOLOGY, MEDICAL AND POPULATION GENETICS, AND METABOLISM. BROAD'S RESEARCHERS BRING EXPERTISE IN DIFFERENT TECHNOLOGY AREAS, CALLED PLATFORMS, TO COLLABORATE ON CHALLENGING PROJECTS THAT COULD NOT BE DONE WITHIN A TYPICAL RESEARCH LABORATORY. TECHNOLOGY AREAS INCLUDE DATA SCIENCES, GENETIC PERTURBATION, GENOMICS, IMAGING, METABOLOMICS AND PROTEOMICS. THE INSTITUTE IS FOCUSED ON USING COLLABORATIVE APPROACHES TO MAKE FOUNDATIONAL ADVANCES IN A NUMBER OF DISEASE AREAS. THESE AREAS INCLUDE CANCER, CARDIOVASCULAR DISEASE, DIABETES, INFECTIOUS DISEASE AND MICROBIOME, KIDNEY DISEASE, OBESITY, PSYCHIATRIC DISORDERS AND RARE DISEASE. THE BROAD INSTITUTE IS COMMITTED TO MAKING THE EXTENSIVE DATA, METHODS, AND TECHNOLOGIES IT GENERATES SECURELY, RAPIDLY AND READILY ACCESSIBLE TO THE SCIENTIFIC COMMUNITY TO DRIVE BIOMEDICAL PROGRESS AROUND THE WORLD. IN RESPONSE TO THE OUTBREAK OF COVID-19, THE BROAD INSTITUTE WORKED WITH THE COMMONWEALTH OF MASSACHUSETTS TO LAUNCH AN EFFORT TO ENGAGE IN LARGE-SCALE COVID-19 DIAGNOSTIC TESTING SERVICES FOR A WIDE VARIETY OF CONSTITUENCIES INCLUDING HOSPITALS, CLINICS, NURSING HOMES, EDUCATIONAL INSTITUTIONS, AND HIGH-IMPACT COMMUNITIES. THE INSTITUTE WAS UNIQUELY POSITIONED TO RESPOND TO THE PUBLIC HEALTH EMERGENCY DUE TO ITS ABILITY TO PROCESS LARGE NUMBERS OF TESTS RAPIDLY, A KEY ELEMENT IN SEEKING TO REDUCE COMMUNITY SPREAD OF COVID-19. THESE LARGE-SCALE DIAGNOSTIC TESTING SERVICES LESSENED THE BURDEN OF GOVERNMENT BY REDUCING THE BURDEN OF IMPORTANT PUBLIC HEALTH CONCERNS THAT WOULD HAVE OTHERWISE FALLEN ON THE GOVERNMENT. TO ACHIEVE THIS GOAL, THE INSTITUTE CONVERTED A CLIA-CERTIFIED LAB INTO A LARGE-SCALE COVID-19 TESTING FACILITY AND CREATED A NOVEL AUTOMATION SYSTEM FOR TEST PROCESSING THAT WAS SCALABLE, MODULAR, AND HIGH-THROUGHPUT. THE INSTITUTE COLLABORATED WITH THE COMMONWEALTH OF MASSACHUSETTS, THE MASSACHUSETTS DEPARTMENT OF PUBLIC HEALTH, AND LOCAL MEDICAL FACILITIES TO PROCESS PATIENT SAMPLES IN ORDER TO MEET PRESSING PUBLIC HEALTH NEEDS. DURING FY23, THE INSTITUTE'S LARGE-SCALE TESTING WAS AN IMPORTANT COMPONENT OF THE COMMONWEALTH OF MASSACHUSETTS' OVERALL EFFORTS TO MANAGE COVID-19, THEREBY PROMOTING THE HEALTH AND WELL BEING OF ALL RESIDENTS. WHILE THE INSTITUTE'S COVID-19 TESTING OPERATIONS HAVE, BY LESSENING THE BURDENS OF GOVERNMENT, FURTHURED THE INSTITUTE'S MISSION, THE INSTITUTE DETERMINED DURING FY23 TO FOCUS ON OTHER ASPECTS OF ITS MISSION AND WOUND DOWN LARGE-SCALE COVID TESTING ACTIVITIES IN JUNE 2023. THE BROAD INSTITUTE HOLDS AN ANNUAL SCIENTIFIC RETREAT, A MULTI-DAY MEETING FEATURING PRESENTATIONS AND POSTERS ON A VARIETY OF RESEARCH PROJECTS ACROSS THE INSTITUTE. IN 2022, THE RETREAT WAS ATTENDED BY APPROXIMATELY 2,500 PARTICIPANTS FROM THE COMMUNITY, BOTH VIRTUALLY AND IN PERSON. THE BROAD'S EDUCATIONAL OUTREACH PROGRAM ENGAGES BOSTON-CAMBRIDGE AREA HIGH SCHOOL STUDENTS IN SCIENTIFIC RESEARCH BY PROVIDING SUMMER INTERNSHIPS AND SEMESTER-LONG RESEARCH PROJECTS. IN 2022, 26 HIGH SCHOOL STUDENTS PARTICIPATED IN A SUMMER SCHOLARS PROGRAM DURING THE ACADEMIC YEAR. IN 2022, AS PART OF THE SEVENTH ANNUAL BROAD SCIENTISTS IN THE CLASSROOM PROGRAM WITH CAMBRIDGE PUBLIC SCHOOLS, BROAD SCIENTISTS VISITED GRADE LEVEL CLASSROOMS AND WORKED WITH STUDENTS THROUGHOUT SCIENCE UNITS. BROAD SERVED APPROXIMATELY 466 STUDENTS THROUGHOUT THIS INITIATIVE. BROAD VOLUNTEERS MENTORED 34 STUDENTS IN THE BIO-CODING CLUB DESIGNED TO ENGAGE 6-8 GRADERS IN THE FIELD OF BIOLOGY. ALSO IN 2022, BROAD PARTICPATED IN SEVERAL EDUCATIONAL EVENTS THROUGHOUT THE LOCAL COMMUNITY. BROAD SCIENTISTS PARTICIPATED IN TALKS AND PRESENTATIONS TO VARIOUS GROUPS ACROSS THE COMMUNITY SUCH AS CAMBRIDGE CITY COUNCIL CANDIDATES, HIGH SCHOOL EDUCATORS AND HIGH SCHOOL AND UNDERGRADUATE STUDENTS. TO HELP INSPIRE YOUNG PEOPLE AND INCREASE THE NUMBER OF SCIENTISTS FROM DIVERSE BACKGROUNDS, THE BROAD'S DIVERSITY INITIATIVE IN SCIENTIFIC RESEARCH OFFERS PROGRAMS FOR INDIVIDUALS FROM HISTORICALLY UNDERREPRESENTED GROUPS AT DIFFERENT STAGES OF THEIR EDUCATION AND CAREERS. IN 2022, 26 HIGH SCHOOL STUDENTS, 19 UNDERGRADUATE STUDENTS AND 8 FACULTY MEMBERS PARTICIPATED IN THESE PROGRAMS. CAREERS. IN 2022, 26 HIGH SCHOOL STUDENTS, 19 UNDERGRADUATE STUDENTS AND 8 FACULTY MEMBERS PARTICIPATED IN THESE PROGRAMS. |
| RELATIONSHIPS AMONG | FORM 990 PART VI, LINE 2 PHILLIP SHARP IS AN EMPLOYEE OF MIT, SALLY KORNBLUTH IS THE PRESIDENT OF MIT AND L. RAFAEL REIF WAS THE FORMER PRESIDENT OF MIT; THEREFORE THEY HAVE A BUSINESS RELATIONSHIP. ALL ARE/WERE DIRECTORS AT THE BROAD INSTITUTE. GEORGE Q. DALEY IS AN EMPLOYEE OF HARVARD, LAWRENCE BACOW WAS THE PRESIDENT OF HARVARD (UNT 6/23), AND SHIRLEY TILGHMAN IS A FELLOW OF HARVARD; THEREFORE THEY HAVE A BUSINESS RELATIONSHIP. ALL ARE DIRECTORS AT THE BROAD INSTITUTE. SHIRLEY TILGHMAN IS THE CHAIR OF CALICO'S SCIENTIFIC BOARD AND ARTHUR LEVINSON IS THE CEO OF CALICO; THEREFORE THEY HAVE A BUSINESS RELATIONSHIP. BOTH ARE DIRECTORS AT THE BROAD INSTITUTE. |
| CHANGES TO ORGANIZATIONAL DOCUMENTS | FORM 990, PART VI, LINE 4 IN AUGUST 2022, CHANGES TO THE INSTITUTE'S ORGANIZATIONAL DOCUMENTS INCLUDE AN AMENDMENT TO THE ARTICLES OF ORGANIZATION TO CLARIFY THE BROAD'S CHARITABLE PURPOSE INCLUDES LESSENING THE BURDENS OF GOVERNMENT. |
| MEMBERS | FORM 990 PART VI, LINE 6 THE MEMBERS OF THE BROAD INSTITUTE CONSIST OF MIT, HARVARD, AND THE ELI AND EDYTHE BROAD FOUNDATION. |
| DECISIONS OF THE GOVERNING BODY SUBJECT TO APPROVAL BY MEMBERS | FORM 990 PART VI, LINE 7A AND 7B BROAD MEMBERS (HARVARD, MIT AND THE BROAD FOUNDATION) EXERCISE ALL POWERS CONSISTENT WITH THE ACTIVITIES AND AFFAIRS OF THE BROAD INSTITUTE. THE MEMBERS HAVE ALL POWERS AND RIGHTS AS ARE VESTED IN THEM BY LAW, THE ARTICLES OF ORGANIZATION AND THE BY-LAWS, WHICH INCLUDE AMENDMENTS TO THE BY-LAWS AND ARTICLES OF INCORPORATION, THE ELECTION OR REPLACEMENT OF DIRECTORS AND DISSOLUTION OF THE INSTITUTE. THE MEMBERS SHALL HOLD AN ANNUAL MEETING FOR ELECTION OF DIRECTORS AND FOR THE CONDUCT OF SUCH OTHER BUSINESS AS MAY COME BEFORE THE MEETING. |
| REVIEW OF 990 | FORM 990, PART VI, LINE 11B THE BROAD INSTITUTE'S FORM 990 WAS PREPARED WITH THE ASSISTANCE OF THE INSTITUTE'S AUDITORS, PRICEWATERHOUSECOOPERS LLP. THE DRAFT FORM 990 WAS PROVIDED TO THE INSTITUTE'S SENIOR MANAGEMENT AND AUDIT, RISK AND COMPLIANCE COMMITTEE OF THE BOARD FOR REVIEW AND COMMENT. THE FULL BOARD RECEIVED A COMPLETED COPY OF THE FORM 990 PRIOR TO THE FORM BEING FILED WITH THE IRS. |
| CONFLICT OF INTEREST POLICY | FORM 990, PART VI, LINE 12C EACH DIRECTOR AND OFFICER HAS A DUTY TO PLACE THE INTEREST OF THE INSTITUTE FOREMOST IN ANY DEALING WITH THE INSTITUTE AND HAS A CONTINUING RESPONSIBILITY TO COMPLY WITH THE REQUIREMENTS OF THIS POLICY. PROMPTLY FOLLOWING THEIR ELECTION OR APPOINTMENT, AND THEREAFTER NOT LATER THAN THE FIRST DAY OF DECEMBER OF EACH YEAR, EACH DIRECTOR AND OFFICER SHALL ACKNOWLEDGE THEIR FAMILIARITY WITH THIS POLICY AND SHALL DISCLOSE IN WRITING TO THE CHAIRMAN OF THE BOARD ANY EXISTING FINANCIAL OR OTHER MATERIAL INTERESTS SUBJECT TO THIS POLICY BY COMPLETING A CONFLICT OF INTEREST DISCLOSURE STATEMENT. THE CONFLICT OF INTEREST DISCLOSURE STATEMENTS SHALL BE REVIEWED BY THE CHAIRMAN OF THE BOARD. ANY ISSUES NOT PREVIOUSLY DISCLOSED SHALL BE REFERRED BY THEM TO THE BOARD OR APPROPRIATE COMMITTEE. THE CONFLICT OF INTEREST DISCLOSURE STATEMENTS SHALL BE RETAINED IN THE CONFIDENTIAL FILES OF THE CHAIRMAN OF THE BOARD. IF A DIRECTOR OR OFFICER DISCLOSES A CONFLICT OF INTEREST TO A PROPOSED OR EXISTING ARRANGEMENT, THE INSTITUTE'S POLICY PLACES CERTAIN RESTRICTIONS ON THEIR ABILITY TO PARTICIPATE IN THE GOVERNING BODY'S DELIBERATIONS AND DECISIONS AROUND THE ARRANGEMENT. IF AN EMPLOYEE WITH THE AUTHORITY TO INFLUENCE BUSINESS DECISIONS DISCLOSES A CONFLICT OF INTEREST RELATED TO A PROPOSED BUSINESS DECISION, THE INSTITUTE'S POLICY PLACES CERTAIN RESTRICTIONS ON THEIR ABILITY TO PARTICIPATE IN THE DECISION-MAKING PROCESS. |
| COMPENSATION | FORM 990, PART VI, LINES 15A AND 15B THE BROAD INSTITUTE MOST RECENTLY ENGAGED A CONSULTING FIRM TO CONDUCT AN INDEPENDENT STUDY FOR THE COMPENSATION OF THE INSTITUTE DIRECTOR IN 2021, AS WELL AS OTHER TOP LEADERSHIP POSITIONS IN 2020 and 2022. THE STUDY FINDINGS WERE PRESENTED TO THE LEADERSHIP, PERSONNEL POLICY AND BOARD GOVERNANCE COMMITTEE FOR REVIEW. THE BOARD OF DIRECTORS' DELIBERATIONS AND DECISIONS WERE CONTEMPORANEOUSLY DOCUMENTED. |
| PUBLIC DISCLOSURE OF DOCUMENTS | FORM 990, PART VI, LINE 18 THE FORM 990 IS MADE AVAILABLE UPON REQUEST AND ON GUIDESTAR.ORG. THE FORM 1023 IS MADE AVAILABLE UPON REQUEST. |
| AVAILABILITY OF DOCUMENTS | FORM 990, PART VI, LINE 19 THE INSTITUTE'S AUDITED FINANCIAL STATEMENTS ARE ATTACHED TO THE ANNUALLY FILED MASSACHUSETTS FORM PC, WHICH IS AVAILABLE TO THE PUBLIC. THE INSTITUTE'S GOVERNING DOCUMENTS AND CONFLICT OF INTEREST POLICY ARE AVAILABLE TO THE PUBLIC UPON REQUEST. |
| OFFICER TITLES | FORM 990, PART VII, LINE 1A WANDA CORDOVA IS AN OFFICER OF THE BROAD INSTITUTE. HER TITLE IS SENIOR ADVISOR TO THE CFO / ASSISTANT TREASURER. HEATHER JANKINS IS A HIGHLY COMPENSATED EMPLOYEE AT THE BROAD INSTITUTE. HER TITLE IS SENIOR DIRECTOR, OPERATIONS AND FINANCES, DSP. JUSTINE LEVIN-ALLERHAND WAS A FORMER OFFICER AT THE BROAD INSTITUTE. HER TITLE WAS CHIEF DEVELOPMENT OFFICER /CLERK (UNTIL 11/21). LAURIE PESSAH IS AN OFFICER AT THE BROAD INSTITUTE. HER TITLE IS BOARD OF DIRECTORS ADMINISTRATOR AND ASSISTANT CLERK. SHE ALSO PERFORMED THE DUTIES OF CLERK IN THE INTERIM PERIOD UNTIL CORRINA HALE WAS APPOINTED CLERK IN SEPTEMBER 2022. |
| RECONCILIATION OF NET ASSETS | FORM 990, PART XI, LINE 9 THE INSTITUTE RECOGNIZED CHANGES IN THE INSTITUTE'S BENEFICIAL INTEREST IN TRUST OF $59,586,586 IN NONOPERATING ACTIVITIES IN ITS FINANCIAL STATEMENTS. |
For Paperwork Reduction Act Notice, see the Instructions for Form 990 or 990-EZ.
Cat. No. 51056K
Schedule O (Form 990) 2021
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