Form990-PF

Department of the Treasury
Internal Revenue Service

Return of Private Foundation
or Section 4947(a)(1) Trust Treated as Private Foundation
right arrowDo not enter social security numbers on this form as it may be made public.
right arrowGo to www.irs.gov/Form990PF for instructions and the latest information.
OMB No. 1545-0047
2023
Open to Public Inspection
For calendar year 2023, or tax year beginning 01-01-2023 , and ending 12-31-2023
Name of foundation
THE MCKNIGHT ENDOWMENT FUND FOR NEUROSCIENCE
 
Number and street (or P.O. box number if mail is not delivered to street address)710 S 2ND ST STE 400
  Room/suite
City or town, state or province, country, and ZIP or foreign postal code
Minneapolis, MN554012290
A Employer identification number

41-1563321
B Telephone number (see instructions)

(612) 333-4220
C right arrow
G Check all that apply:

D 1. Foreign organizations, check here............. right arrow
2. Foreign organizations meeting the 85%
test, check here and attach computation ... right arrow
E right arrow
H Check type of organization:
F right arrow
I Fair market value of all assets at end
of year (from Part II, col. (c),
line 16)right arrow$25,588J Accounting method:
 
(Part I, column (d) must be on cash basis.)
Part I Analysis of Revenue and Expenses (The total of amounts in columns (b), (c), and (d) may not necessarily equal the amounts in column (a) (see instructions).) (a) Revenue and
expenses per
books 		(b) Net investment
income 		(c) Adjusted net
income 		(d) Disbursements
for charitable
purposes
(cash basis only)
Revenue 1 Contributions, gifts, grants, etc., received (attach schedule) 3,800,550
2 Check right arrow.............
3 Interest on savings and temporary cash investments      
4 Dividends and interest from securities...      
5a Gross rents............      
b Net rental income or (loss)  
6a Net gain or (loss) from sale of assets not on line 10 0
b Gross sales price for all assets on line 6a  
7 Capital gain net income (from Part IV, line 2)... 0
8 Net short-term capital gain.........  
9 Income modifications...........  
10a Gross sales less returns and allowances 0
b Less: Cost of goods sold.... 0
c Gross profit or (loss) (attach schedule)..... 0  
11 Other income (attach schedule)....... 0 0 0
12 Total. Add lines 1 through 11........ 3,800,550 0 0
Operating and Administrative Expenses 13 Compensation of officers, directors, trustees, etc. 34,000     34,000
14 Other employee salaries and wages......        
15 Pension plans, employee benefits.......        
16a Legal fees (attach schedule)......... 0 0 0 0
b Accounting fees (attach schedule)....... Click to see attachment
List of Attached Documents:
// Content
9,885 0 0 9,885
c Other professional fees (attach schedule).... Click to see attachment
List of Attached Documents:
// Content
132,000 0 0 132,000
17 Interest...............        
18 Taxes (attach schedule) (see instructions)... 0 0 0 0
19 Depreciation (attach schedule) and depletion... 0 0 0
20 Occupancy..............        
21 Travel, conferences, and meetings....... 396,421     396,421
22 Printing and publications..........        
23 Other expenses (attach schedule)....... Click to see attachment
List of Attached Documents:
// Content
19,674 0 0 19,674
24 Total operating and administrative expenses.
Add lines 13 through 23.......... 591,980 0 0 591,980
25 Contributions, gifts, grants paid....... 3,207,413 3,207,413
26 Total expenses and disbursements. Add lines 24 and 25 3,799,393 0 0 3,799,393
27 Subtract line 26 from line 12:
a Excess of revenue over expenses and disbursements 1,157
b Net investment income (if negative, enter -0-) 0
c Adjusted net income (if negative, enter -0-)... 0
For Paperwork Reduction Act Notice, see instructions.
Cat. No. 11289X Form 990-PF (2023)
Form 990-PF (2023)
Page 2
Part II Balance Sheets Attached schedules and amounts in the description column
should be for end-of-year amounts only. (See instructions.) 		Beginning of year End of year
(a) Book Value (b) Book Value (c) Fair Market Value
Assets 1 Cash—non-interest-bearing............. 24,431 25,588 25,588
2 Savings and temporary cash investments.........      
3 Accounts receivable right arrow  
Less: allowance for doubtful accounts right arrow   0 0 0
4 Pledges receivable right arrow  
Less: allowance for doubtful accounts right arrow   0 0 0
5 Grants receivable.................      
6 Receivables due from officers, directors, trustees, and other
disqualified persons (attach schedule) (see instructions)..... 0 0 0
7 Other notes and loans receivable (attach schedule) right arrow0
Less: allowance for doubtful accounts right arrow0 0 0 0
8 Inventories for sale or use..............      
9 Prepaid expenses and deferred charges..........      
10a Investments—U.S. and state government obligations (attach schedule) 0 0 0
b Investments—corporate stock (attach schedule)....... 0 Click to see attachment
List of Attached Documents:
// Content
0 		0
c Investments—corporate bonds (attach schedule)....... 0   0
11 Investments—land, buildings, and equipment: basis right arrow0
Less: accumulated depreciation (attach schedule) right arrow0 0   0
12 Investments—mortgage loans.............      
13 Investments—other (attach schedule).......... 0 0 0
14 Land, buildings, and equipment: basis right arrow0
Less: accumulated depreciation (attach schedule) right arrow0 0   0
15 Other assets (describe right arrow) 0 0 0
16 Total assets (to be completed by all filers—see the
instructions. Also, see page 1, item I) 24,431 25,588 25,588
Liabilities 17 Accounts payable and accrued expenses..........    
18 Grants payable.................    
19 Deferred revenue.................    
20 Loans from officers, directors, trustees, and other disqualified persons 0 0
21 Mortgages and other notes payable (attach schedule)...... 0 0
22 Other liabilities (describe right arrow)    
23 Total liabilities (add lines 17 through 22)......... 0 0
Net Assets or Fund Balances Foundations that follow FASB ASC 958, check here right arrow
and complete lines 24, 25, 29 and 30.
24 Net assets without donor restrictions...........    
25 Net assets with donor restrictions............    
Foundations that do not follow FASB ASC 958, check here right arrow
and complete lines 26 through 30.
26 Capital stock, trust principal, or current funds........    
27 Paid-in or capital surplus, or land, bldg., and equipment fund    
28 Retained earnings, accumulated income, endowment, or other funds 24,431 25,588
29 Total net assets or fund balances (see instructions)..... 24,431 25,588
30 Total liabilities and net assets/fund balances (see instructions). 24,431 25,588
Part III
Analysis of Changes in Net Assets or Fund Balances
1
Total net assets or fund balances at beginning of year—Part II, column (a), line 29 (must agree with end-of-year figure reported on prior year’s return) ...............
1
24,431
2
Enter amount from Part I, line 27a .....................
2
1,157
3
Other increases not included in line 2 (itemize) right arrow
3
0
4
Add lines 1, 2, and 3 ..........................
4
25,588
5
Decreases not included in line 2 (itemize) right arrow
5
0
6
Total net assets or fund balances at end of year (line 4 minus line 5)—Part II, column (b), line 29 .
6
25,588
Form 990-PF (2023)
Form 990-PF (2023)
Page 3
Part IV
Capital Gains and Losses for Tax on Investment Income
(a) List and describe the kind(s) of property sold (e.g., real estate,
2-story brick warehouse; or common stock, 200 shs. MLC Co.)		 (b)
How acquired
P—Purchase
D—Donation 		(c)
Date acquired
(mo., day, yr.) 		(d)
Date sold
(mo., day, yr.)
1a
b
c
d
e
(e)
Gross sales price 		(f)
Depreciation allowed
(or allowable) 		(g)
Cost or other basis
plus expense of sale 		(h)
Gain or (loss)
(e) plus (f) minus (g)
a
b
c
d
e
Complete only for assets showing gain in column (h) and owned by the foundation on 12/31/69 (l)
Gains (Col. (h) gain minus
col. (k), but not less than -0-) or
Losses (from col.(h))
(i)
F.M.V. as of 12/31/69 		(j)
Adjusted basis
as of 12/31/69 		(k)
Excess of col. (i)
over col. (j), if any
a
b
c
d
e
2 Capital gain net income or (net capital loss) Bracket If gain, also enter in Part I, line 7
If (loss), enter -0- in Part I, line 7		 Bracket 2 0
3 Net short-term capital gain or (loss) as defined in sections 1222(5) and (6):
If gain, also enter in Part I, line 8, column (c) (see instructions). If (loss), enter -0-
in Part I, line 8 ................... 		Bracket 3 0
Part V
Excise Tax Based on Investment Income (Section 4940(a), 4940(b), 4940(e), or 4948—see instructions)
1a Exempt operating foundations described in section 4940(d)(2), check here right arrow and enter “N/A" on line 1. Bracket for line 1a
Date of ruling or determination letter:   (attach copy of letter if necessary–see instructions) 1 0
b All other domestic foundations enter 1.39% (0.0139) of line 27b. Exempt foreign organizations enter 4% (0.04) of Part I, line 12, col. (b)
2 Tax under section 511 (domestic section 4947(a)(1) trusts and taxable foundations only. Others enter -0-) 2  
3 Add lines 1 and 2........................... 3 0
4 Subtitle A (income) tax (domestic section 4947(a)(1) trusts and taxable foundations only. Others enter -0-) 4  
5 Tax based on investment income. Subtract line 4 from line 3. If zero or less, enter -0- ..... 5 0
6 Credits/Payments:
a 2023 estimated tax payments and 2022 overpayment credited to 2023 6a 0
b Exempt foreign organizations—tax withheld at source...... 6b  
c Tax paid with application for extension of time to file (Form 8868)... 6c  
d Backup withholding erroneously withheld .......... 6d  
7 Total credits and payments. Add lines 6a through 6d.............. 7 0
8 Enter any penalty for underpayment of estimated tax. Check here if Form 2220 is attached. 8  
9 Tax due. If the total of lines 5 and 8 is more than line 7, enter amount owed.......right arrow 9 0
10 Overpayment. If line 7 is more than the total of lines 5 and 8, enter the amount overpaid...right arrow 10  
11 Enter the amount of line 10 to be: Credited to 2024 estimated taxright arrow   Refundedright arrow 11 0
Form 990-PF (2023)
Form 990-PF (2023)
Page 4
Part VI-A
Statements Regarding Activities
1a
During the tax year, did the foundation attempt to influence any national, state, or local legislation or did
Yes
No
it participate or intervene in any political campaign? ....................
1a
 
No
b
Did it spend more than $100 during the year (either directly or indirectly) for political purposes? See the instructions
for the definition.................................
1b
 
No
If the answer is "Yes" to 1a or 1b, attach a detailed description of the activities and copies of any materials
published or distributed by the foundation in connection with the activities.
c
Did the foundation file Form 1120-POL for this year?.....................
1c
 
No
d
Enter the amount (if any) of tax on political expenditures (section 4955) imposed during the year:
(1) On the foundation. right arrow$   (2) On foundation managers.right arrow$  
e
Enter the reimbursement (if any) paid by the foundation during the year for political expenditure tax imposed
on foundation managers.right arrow$  
2
Has the foundation engaged in any activities that have not previously been reported to the IRS?.......
2
 
No
If "Yes," attach a detailed description of the activities.
3
Has the foundation made any changes, not previously reported to the IRS, in its governing instrument, articles
of incorporation, or bylaws, or other similar instruments? If "Yes," attach a conformed copy of the changes....
3
 
No
4a
Did the foundation have unrelated business gross income of $1,000 or more during the year?.........
4a
 
No
b
If "Yes," has it filed a tax return on Form 990-T for this year?...................
4b
 
 
5
Was there a liquidation, termination, dissolution, or substantial contraction during the year?.........
5
 
No
If "Yes," attach the statement required by General Instruction T.
6
Are the requirements of section 508(e) (relating to sections 4941 through 4945) satisfied either:
round bullet By language in the governing instrument, or
round bullet By state legislation that effectively amends the governing instrument so that no mandatory directions
that conflict with the state law remain in the governing instrument? ................
6
Yes
 
7
Did the foundation have at least $5,000 in assets at any time during the year? If "Yes," complete Part II, col. (c),
and Part XIV..................................
7
Yes
 
8a
Enter the states to which the foundation reports or with which it is registered (see instructions)
right arrowMN
b
If the answer is "Yes" to line 7, has the foundation furnished a copy of Form 990-PF to the Attorney
General (or designate) of each state as required by General Instruction G? If "No," attach explanation .
8b
Yes
 
9
Is the foundation claiming status as a private operating foundation within the meaning of section 4942(j)(3)
or 4942(j)(5) for calendar year 2023 or the taxable year beginning in 2023? See the instructions for Part XIII.
If "Yes," complete Part XIII .............................
9
Yes
 
10
Did any persons become substantial contributors during the tax year? If "Yes," attach a schedule listing their names
and addresses. ...............................
10
 
No
11
At any time during the year, did the foundation, directly or indirectly, own a controlled entity within the
meaning of section 512(b)(13)? If "Yes," attach schedule. See instructions .............
11
 
No
12
Did the foundation make a distribution to a donor advised fund over which the foundation or a disqualified person had
advisory privileges? If "Yes," attach statement. See instructions.................
12
 
No
13
Did the foundation comply with the public inspection requirements for its annual returns and exemption application?
13
Yes
 
Website addressright arrowhttps://www.mcknight.org/programs/the-mcknight-endowment-fund-for-neuroscience/
14
The books are in care ofright arrowNichol Higdon Telephone no.right arrow (612) 333-4220

Located atright arrow710 S 2ND ST STE 400MinneapolisMN ZIP+4right arrow554012290
15
Section 4947(a)(1) nonexempt charitable trusts filing Form 990-PF in lieu of Form 1041 —check here .........right arrow
and enter the amount of tax-exempt interest received or accrued during the year ........right arrow
15
 
16 At any time during calendar year 2023, did the foundation have an interest in or a signature or other authority over YesNo
a bank, securities, or other financial account in a foreign country? .................
16   No
See the instructions for exceptions and filing requirements for FinCEN Form 114. If "Yes", enter the name of the foreign
country right arrow
Form 990-PF (2023)
Form 990-PF (2023)
Page 5
Part VI-B
Statements Regarding Activities for Which Form 4720 May Be Required
File Form 4720 if any item is checked in the "Yes" column, unless an exception applies.
Yes
No
1a
During the year did the foundation (either directly or indirectly):
(1) Engage in the sale or exchange, or leasing of property with a disqualified person? ...........
1a(1)
 
No
(2) Borrow money from, lend money to, or otherwise extend credit to (or accept it from)
a disqualified person? ..............................
1a(2)
 
No
(3) Furnish goods, services, or facilities to (or accept them from) a disqualified person? ...........
1a(3)
 
No
(4) Pay compensation to, or pay or reimburse the expenses of, a disqualified person? ............
1a(4)
Yes
 
(5) Transfer any income or assets to a disqualified person (or make any of either available
for the benefit or use of a disqualified person)? ......................
1a(5)
 
No
(6) Agree to pay money or property to a government official? (Exception. Check "No"
if the foundation agreed to make a grant to or to employ the official for a period
after termination of government service, if terminating within 90 days.) ...............
1a(6)
 
No
b
If any answer is "Yes" to 1a(1)–(6), did any of the acts fail to qualify under the exceptions described in Regulations
section 53.4941(d)-3 or in a current notice regarding disaster assistance? See instructions ..........
1b
 
No
c
Organizations relying on a current notice regarding disaster assistance check here ........right arrow
d
Did the foundation engage in a prior year in any of the acts described in 1a, other than excepted acts,
that were not corrected before the first day of the tax year beginning in 2023? .............
1d
 
No
2
Taxes on failure to distribute income (section 4942) (does not apply for years the foundation was a private
operating foundation defined in section 4942(j)(3) or 4942(j)(5)):
a
At the end of tax year 2023, did the foundation have any undistributed income (Part XII, lines 6d
and 6e) for tax year(s) beginning before 2023?....................
2a
 
No
If "Yes," list the years right arrow20, 20, 20, 20
b
Are there any years listed in 2a for which the foundation is not applying the provisions of section 4942(a)(2)
(relating to incorrect valuation of assets) to the year’s undistributed income? (If applying section 4942(a)(2)
to all years listed, answer "No" and attach statement—see instructions.) ..............
2b
 
 
c
If the provisions of section 4942(a)(2) are being applied to any of the years listed in 2a, list the years here.
right arrow20, 20, 20, 20
3a
Did the foundation hold more than a 2% direct or indirect interest in any business enterprise at
any time during the year? ..............................
3a
 
No
b
If "Yes," did it have excess business holdings in 2023 as a result of (1) any purchase by the foundation
or disqualified persons after May 26, 1969; (2) the lapse of the 5-year period (or longer period approved
by the Commissioner under section 4943(c)(7)) to dispose of holdings acquired by gift or bequest; or (3)
the lapse of the 10-, 15-, or 20-year first phase holding period? (Use Schedule C, Form 4720, to determine
if the foundation had excess business holdings in 2023.) .....................
3b
 
 
4a
Did the foundation invest during the year any amount in a manner that would jeopardize its charitable purposes?
4a
 
No
b
Did the foundation make any investment in a prior year (but after December 31, 1969) that could jeopardize its
charitable purpose that had not been removed from jeopardy before the first day of the tax year beginning in 2023? ..
4b
 
No
Form 990-PF (2023)
Form 990-PF (2023)
Page 6
Part VI-B
Statements Regarding Activities for Which Form 4720 May Be Required (continued)
5a
During the year did the foundation pay or incur any amount to:
Yes
No
(1) Carry on propaganda, or otherwise attempt to influence legislation (section 4945(e))? ..........
5a(1)
 
No
(2) Influence the outcome of any specific public election (see section 4955); or to carry
on, directly or indirectly, any voter registration drive? ....................
5a(2)
 
No
(3) Provide a grant to an individual for travel, study, or other similar purposes? .............
5a(3)
 
No
(4) Provide a grant to an organization other than a charitable, etc., organization described
in section 4945(d)(4)(A)? See instructions ........................
5a(4)
 
No
(5) Provide for any purpose other than religious, charitable, scientific, literary, or
educational purposes, or for the prevention of cruelty to children or animals? .............
5a(5)
 
No
b
If any answer is "Yes" to 5a(1)–(5), did any of the transactions fail to qualify under the exceptions described in
Regulations section 53.4945 or in a current notice regarding disaster assistance? See instructions ........
5b
 
 
c
Organizations relying on a current notice regarding disaster assistance check .........right arrow
d
If the answer is "Yes" to question 5a(4), does the foundation claim exemption from the
tax because it maintained expenditure responsibility for the grant? .................
5d
 
 
If "Yes," attach the statement required by Regulations section 53.4945–5(d).
6a
Did the foundation, during the year, receive any funds, directly or indirectly, to pay premiums on
a personal benefit contract? .............................
6a
 
No
b
Did the foundation, during the year, pay premiums, directly or indirectly, on a personal benefit contract? ....
6b
 
No
If "Yes" to 6b, file Form 8870.
7a
At any time during the tax year, was the foundation a party to a prohibited tax shelter transaction?
7a
 
No
b
If "Yes", did the foundation receive any proceeds or have any net income attributable to the transaction? .....
7b
 
 
8
Is the foundation subject to the section 4960 tax on payment(s) of more than $1,000,000 in remuneration or
excess parachute payment during the year? .........................
8
 
No
Part VII
Information About Officers, Directors, Trustees, Foundation Managers, Highly Paid Employees,
and Contractors
1 List all officers, directors, trustees, foundation managers and their compensation. See instructions
(a) Name and address (b) Title, and average
hours per week
devoted to position 		(c) Compensation
 (If not paid, enter
-0-) 		(d) Contributions to employee benefit plans and deferred compensation (e) Expense account,
other allowances
Kara Carlisle DIRECTOR (Through June 2023)
0.200 		0 0 0
710 Second Street South Suite 400
Minneapolis,MN554012290
Kelsey Martin MD PhD Vice President
1.100 		9,000 0 0
710 S 2ND ST STE 400
Minneapolis,MN554012290
Stephanie Duffy Secretary/Treasurer (Beginning June 2023)
0.200 		0 0 0
710 S 2ND ST STE 400
Minneapolis,MN554012290
Catherine Dulac Director
0.200 		1,000 0 0
710 S 2ND ST STE 400
Minneapolis,MN554012290
Dana Anderson Director
0.200 		0 0 0
710 S 2ND ST STE 400
Minneapolis,MN554012290
J Anthony Movshon PhD President
1.300 		11,000 0 0
710 S 2ND ST STE 400
Minneapolis,MN554012290
Leslie Vosshall Director
0.200 		1,000 0 0
710 S 2ND ST STE 400
Minneapolis,MN554012290
Markus Meister Director
0.400 		2,000 0 0
710 S 2ND ST STE 400
Minneapolis,MN554012290
Michael D Ehlers MD PhD Director
0.200 		0 0 0
710 S 2ND ST STE 400
Minneapolis,MN554012290
Ming Guo MD PhD Director
1.100 		5,000 0 0
710 S 2ND ST STE 400
Minneapolis,MN554012290
Richard Mooney Director
1.100 		5,000 0 0
710 S 2ND ST STE 400
Minneapolis,MN554012290
ERIKA BINGER SECRETARY/TREASURER (Through June 2023)
0.900 		0 0 0
710 Second Street South Suite 400
Minneapolis,MN554012290
2 Compensation of five highest-paid employees (other than those included on line 1—see instructions). If none, enter “NONE."
(a) Name and address of each employee paid more than $50,000 (b) Title, and average
hours per week
devoted to position 		(c) Compensation (d) Contributions to
employee benefit
plans and deferred
compensation 		(e) Expense account,
other allowances
 
Total number of other employees paid over $50,000...................right arrow 0
Form 990-PF (2023)
Form 990-PF (2023)
Page 7
Part VII
Information About Officers, Directors, Trustees, Foundation Managers, Highly Paid Employees,
and Contractors (continued)
3 Five highest-paid independent contractors for professional services (see instructions). If none, enter "NONE".
(a) Name and address of each person paid more than $50,000 (b) Type of service (c) Compensation
The McKnight Foundation Administrative Services 100,000
710 S 2ND ST STE 400
Minneapolis,MN554012290
Total number of others receiving over $50,000 for professional services.............right arrow  
Part VIII-A
Summary of Direct Charitable Activities
List the foundation’s four largest direct charitable activities during the tax year. Include relevant statistical information such as the number of organizations and other beneficiaries served, conferences convened, research papers produced, etc. Expenses
1 See Supplemental Information 380,575
2  
3  
4  
Part VIII-B
Summary of Program-Related Investments (see instructions)
Describe the two largest program-related investments made by the foundation during the tax year on lines 1 and 2. Amount
1 N/A  
2  
All other program-related investments. See instructions.
3  
Total. Add lines 1 through 3.........................right arrow0
Form 990-PF (2023)
Form 990-PF (2023)
Page 8
Part IX
Minimum Investment Return (All domestic foundations must complete this part. Foreign foundations, see instructions.)
1
Fair market value of assets not used (or held for use) directly in carrying out charitable, etc.,
purposes:
a
Average monthly fair market value of securities...................
1a
0
b
Average of monthly cash balances.......................
1b
1,130,334
c
Fair market value of all other assets (see instructions)................
1c
0
d
Total (add lines 1a, b, and c).........................
1d
1,130,334
e
Reduction claimed for blockage or other factors reported on lines 1a and
1c (attach detailed explanation) .............
1e
0
2
Acquisition indebtedness applicable to line 1 assets..................
2
 
3
Subtract line 2 from line 1d.........................
3
1,130,334
4
Cash deemed held for charitable activities. Enter 1.5% (0.015) of line 3 (for greater amount, see
instructions) .............................
4
16,955
5
Net value of noncharitable-use assets. Subtract line 4 from line 3. ............
5
1,113,379
6
Minimum investment return. Enter 5% (0.05) of line 5................
6
55,669
Part X
Distributable Amount (see instructions) (Section 4942(j)(3) and (j)(5) private operating foundations and certain foreign organizations check here right arrow and do not complete this part.)
1
Minimum investment return from Part IX, line 6..................
1
 
2a
Tax on investment income for 2022 from Part V, line 5.......
2a
 
b
Income tax for 2022. (This does not include the tax from Part V.) ...
2b
 
c
Add lines 2a and 2b............................
2c
 
3
Distributable amount before adjustments. Subtract line 2c from line 1............
3
 
4
Recoveries of amounts treated as qualifying distributions................
4
 
5
Add lines 3 and 4............................
5
 
6
Deduction from distributable amount (see instructions).................
6
 
7
Distributable amount as adjusted. Subtract line 6 from line 5. Enter here and on Part XII, line 1 ...
7
 
Part XI
Qualifying Distributions (see instructions)
1
Amounts paid (including administrative expenses) to accomplish charitable, etc., purposes:
a
Expenses, contributions, gifts, etc.—total from Part I, column (d), line 26 ..........
1a
3,799,393
b
Program-related investments—total from Part VIII-B..................
1b
0
2
Amounts paid to acquire assets used (or held for use) directly in carrying out charitable, etc.,
purposes...............................
2
 
3
Amounts set aside for specific charitable projects that satisfy the:
a
Suitability test (prior IRS approval required)....................
3a
 
b
Cash distribution test (attach the required schedule) .................
3b
0
4
Qualifying distributions. Add lines 1a through 3b. Enter here and on Part XII, line 4. .......
4
3,799,393
Form 990-PF (2023)
Form 990-PF (2023)
Page 9
Part XII
Undistributed Income (see instructions)
(a)
Corpus 		(b)
Years prior to 2022 		(c)
2022 		(d)
2023
1 Distributable amount for 2023 from Part X, line 7  
2 Undistributed income, if any, as of the end of 2022:
a Enter amount for 2022 only.......  
b Total for prior years:20 , 20, 20  
3 Excess distributions carryover, if any, to 2022:
a From 2018......  
b From 2019......  
c From 2020......  
d From 2021......  
e From 2022......  
f Total of lines 3a through e ........  
4Qualifying distributions for 2023 from Part
XI, line 4: right arrow$  
a Applied to 2022, but not more than line 2a  
b Applied to undistributed income of prior years
(Election required—see instructions)..... 		 
c Treated as distributions out of corpus (Election
required—see instructions)........ 		 
d Applied to 2023 distributable amount.....  
e Remaining amount distributed out of corpus  
5 Excess distributions carryover applied to 2023.    
(If an amount appears in column (d), the
same amount must be shown in column (a).)
6Enter the net total of each column as
indicated below:
a Corpus. Add lines 3f, 4c, and 4e. Subtract line 5  
b Prior years’ undistributed income. Subtract
line 4b from line 2b .......... 		 
c Enter the amount of prior years’ undistributed
income for which a notice of deficiency has
been issued, or on which the section 4942(a)
tax has been previously assessed...... 		 
d Subtract line 6c from line 6b. Taxable amount
—see instructions ........... 		 
e Undistributed income for 2022. Subtract line
4a from line 2a. Taxable amount—see
instructions ............. 		 
f Undistributed income for 2023. Subtract
lines 4d and 5 from line 1. This amount must
be distributed in 2024 .......... 		 
7 Amounts treated as distributions out of
corpus to satisfy requirements imposed by
section 170(b)(1)(F) or 4942(g)(3) (Election may
be required - see instructions) ....... 		 
8 Excess distributions carryover from 2018 not
applied on line 5 or line 7 (see instructions) ... 		 
9 Excess distributions carryover to 2024.
Subtract lines 7 and 8 from line 6a ...... 		 
10 Analysis of line 9:
a Excess from 2019....  
b Excess from 2020....  
c Excess from 2021....  
d Excess from 2022....  
e Excess from 2023....  
Form 990-PF (2023)
Form 990-PF (2023)
Page 10
Part XIII
Private Operating Foundations (see instructions and Part VI-A, question 9)
1a If the foundation has received a ruling or determination letter that it is a private operating
foundation, and the ruling is effective for 2023, enter the date of the ruling ...... right arrow
 
b Check box to indicate whether the organization is a private operating foundation described in section or
2a Enter the lesser of the adjusted net
income from Part I or the minimum
investment return from Part IX for each
year listed .......... 		Tax year Prior 3 years (e) Total
(a) 2023 (b) 2022 (c) 2021 (d) 2020
0 0 0 39 39
b 85% (0.85) of line 2a ......... 0 0 0 33 33
c Qualifying distributions from Part XI,
line 4 for each year listed ..... 		3,799,393 3,772,957 3,593,792 3,456,889 14,623,031
d Amounts included in line 2c not used directly
for active conduct of exempt activities .......... 		3,125,000 3,120,612 3,125,000 3,150,000 12,520,612
e Qualifying distributions made directly
for active conduct of exempt activities.
Subtract line 2d from line 2c .... 		674,393 652,345 468,792 306,889 2,102,419
3 Complete 3a, b, or c for the
alternative test relied upon:
a “Assets" alternative test—enter:
(1) Value of all assets ......          
(2) Value of assets qualifying
under section 4942(j)(3)(B)(i)		          
b “Endowment" alternative test— enter 2/3
of minimum investment return shown in
Part IX, line 6 for each year listed .. 		37,113 37,157 30,677 27,950 132,896
c “Support" alternative test—enter:
(1) Total support other than gross
investment income (interest,
dividends, rents, payments
on securities loans (section
512(a)(5)), or royalties) .... 		         
(2) Support from general public
and 5 or more exempt
organizations as provided in
section 4942(j)(3)(B)(iii).... 		         
(3) Largest amount of support
from an exempt organization		          
(4) Gross investment income          
Part XIV
Supplementary Information (Complete this part only if the foundation had $5,000 or more in
assets at any time during the year—see instructions.)
1Information Regarding Foundation Managers:
aList any managers of the foundation who have contributed more than 2% of the total contributions received by the foundation
before the close of any tax year (but only if they have contributed more than $5,000). (See section 507(d)(2).)
NONE
bList any managers of the foundation who own 10% or more of the stock of a corporation (or an equally large portion of the
ownership of a partnership or other entity) of which the foundation has a 10% or greater interest.
NONE
2Information Regarding Contribution, Grant, Gift, Loan, Scholarship, etc., Programs:
Check here right arrow
aThe name, address, and telephone number or e-mail address of the person to whom applications should be addressed:
MEFN Selection Committee
710 S 2ND ST STE 400
Minneapolis,MN554012290
(612) 333-4220
neuro@mcknight.org
bThe form in which applications should be submitted and information and materials they should include:
SEE SUPPLEMENTAL INFORMATION
cAny submission deadlines:
SEE SUPPLEMENTAL INFORMATION
dAny restrictions or limitations on awards, such as by geographical areas, charitable fields, kinds of institutions, or other
factors:
See Supplemental Information
Form 990-PF (2023)
Form 990-PF (2023)
Page 11
Part XIV
Supplementary Information (continued)
3 Grants and Contributions Paid During the Year or Approved for Future Payment
Recipient If recipient is an individual,
show any relationship to
any foundation manager
or substantial contributor
 Foundation
status of
recipient 		Purpose of grant or
contribution 		Amount
Name and address (home or business)
aPaid during the year

Albert Einstein College of Medicine

1300 Morris Park Ave Ste 402
New York,NY10461 		NONE PC Unravelling the mechanisms of synapse development, from molecules to behavior. Principal Investigator: Dr. Peri Kurshan 75,000

Brigham and Women's HospitalHarvard Medical School

60 Fenwood Rd Hale Building Room 70
02L
Boston,MA02115 		NONE PC The Neurobiology of Glioma: Understanding Malignant Neural Circuits Instructing Tumor Growth. Principal Investigator: Humsa Venkatesh,Ph.D. 100,000

Cold Spring Harbor Laboratory

1 Bungtown Road Beckman Room 319
Cold Spring Harbor,NY11724 		NONE PC Uncovering the Molecular Basis of Microglial Function in the Stimulated Brain. Principal Investigator: Lucas Cheadle 75,000

Columbia University

3227 Broadway
New York,NY10027 		NONE PC Connectrome-constrained Models of Adaptive Behavior. Principal Investigator: Ashok Litwin-Kumar 75,000

Columbia University

3227 Broadway
New York,NY10027 		NONE PC Cortical circuits for perceiving visual form. Principal Investigator: Dr. Yasmine El-Shamayleh 75,000

Columbia University

3227 Broadway
New York,NY10027 		NONE PC Neural Mechanisms of Courtship and Monogamy. Principal Investigator: Dr. Vikram Gadagkar 75,000

Columbia University

3227 Broadway
New York,NY10027 		NONE PC Skin-brain axis for rewarding touch behaviors. Principal Investigator: Dr. Ishmail Abdus-Saboor 75,000

Fred Hutchinson Cancer Research Center

1100 Fairview Ave N PO Box 19024
Seattle,WA98109 		NONE PC Adipocyte-brain mitochondrial signaling and its impacts on brain function. Principal Investigator: Akhila Rajan,Ph.D. 100,000

Harvard Medical School

220 Longwood Avenue Armenise 429
Boston,MA02115 		NONE PC Multiscale Neural Network Models to Infer Functional Motifs in the Brain. Principal Investigator: Kanaka Rajan, Ph.D. 75,000

Massachusetts General Hospital

185 Cambridge Street Simches Resear
ch Center Room 6808
Boston,MA02114 		NONE PC Development, Function, and Dysfunction of Somatosensory and Viscerosensory Systems in Autism Spectrum Disorder. Principal Investigator: Lauren Orefice, Ph.D. 75,000

Massachusetts Institute of Technology

60 Vassar St Room 39-229
Cambridge,MA02139 		NONE PC Linking Neural Circuits and Fluid Dynamics in the Sleeping Brain. Principal Investigator: Laura Lewis 75,000

Max Planck Florida Institute

1 Max Planck Way
Jupiter,FL33458 		NONE PC Synaptic mechanisms and network dynamics underlying motor learning. Principal Investigator: Dr. Hidehiko Inagaki 75,000

New York University

4 Washington Place Room 621
New York,NY10003 		NONE PC Coordinate Transforms in the Mouse Cortex. Principal Investigator: David Schneider 75,000

New York University

4 Washington Place Room 621
New York,NY10003 		NONE PC Modulation of striatal cells and synapses by dopamine movement signals. Principal Investigator: Dr. Tanya Sippy 75,000

New York University

4 Washington Place Room 621
New York,NY10003 		NONE PC Neural Circuit Mechanisms of Inference. Principal Investigator: Christine Constantinople, Ph.D 75,000

Northwestern University Feinberg School of Medicine

303 E Superior St Lurie 7-109
Chicago,IL60611 		NONE GOV Dissecting the Gut-brain Dynamics Underlying Anorexia. Principal Investigator: Lisa Beutler 100,000

Oregon Health & Science University

3181 SW Sam Jackson Park Road L623
Portland,OR97239 		NONE GOV Mechanosensation for guiding cellular morphology. Principal Investigator: Dr. Swetha Murthy 75,000

St Jude Children's Research Hospital

262 Danny Thomas Place
Memphis,TN38112 		NONE PC Identifying Brain Circuits that Connect Respiration and Cognitive State. Principal Investigator: Lindsey Schwarz 100,000

Stanford University

371 Jane Stanford Way
Stanford,CA94305 		NONE PC How Does the Brain Compute Using Activity Distributed Across Populations and Brain Areas? Principal Investigator: Shaul Druckmann 75,000

Stanford University

371 Jane Stanford Way
Stanford,CA94305 		NONE PC Machine Learning Methods for Discovering Structure in Neural and Behavioral Data. Principal Investigator: Dr. Scott Linderman 75,000

Stanford University School of Medicine

401 Quarry Rd
Palo Alto,CA94304 		NONE PC Neuron-to-OPC synapses in adaptive and maladaptive myelination. Principal Investigator: Juliet K. Knowles, MD, PhD 100,000

Syracuse University

640 Skytop Road
Syracuse,NY13244 		NONE PC Two-photon tracking technology to read and manipulate neural patterns in freely moving animals. Principal Investigator: Mirna Mihovilovic Skanata 100,000

The Regents of the University of California

201 Gilman Hall UC Berkeley
Berkeley,CA94702 		NONE GOV Evolution of neural diversity and patterning in the visual system. Principal Investigator: Dr. Karthik Shekhar 75,000

The Regents of the University of California

201 Gilman Hall UC Berkeley
Berkeley,CA94702 		NONE GOV Illuminating Oxytocin Signaling in the Brain with Near-Infrared Fluorescent Nanosensors. Principal Investigator: Markita Landry, Ph.D. 75,000

The Regents of the University of California

142 Weill Hall 3200
Berkeley,CA94702 		NONE GOV Neurotensin mediated regulation of hedonic feeding behavior and obesity. Principal Investigator: Stephan Lammel Ph.D. 100,000

The Trustees of Princeton University

Washington Road
Princeton,NJ08544 		NONE PC Proportional-Integral Feedback in a Biological 'Gyroscope'. Principal Investigator: Bradley Dickerson, Ph.D. 75,000

University of Alabama at Birmingham

1825 University Blvd SHEL 910
Birmingham,AL35294 		NONE PC Leveraging Single-cell Epigenomics for Targeted Manipulation of Drug-activated Ensemble. Principal Investigator: Jeremy Day & Ian Maze 100,000

University of Illinois at Chicago

840 W Taylor St
Chicago,IL60607 		NONE GOV Sub-10 nm spatial profiling of synaptic proteins and RNA transcripts with high-isotropy expansion microscopy using a highly homogenous hydrogel constructed from tetrahedron-like monomers. Principal Investigator: Ruixuan Gao, Ph.D. 100,000

University of Iowa

169 Newton Rd 2400 PBDB
Iowa City,IA52242 		NONE GOV Brain-wide Electrical Connectivity in Migraine: Toward the Development of Network Based Therapeutics. Principal Investigator: Rainbo Hultman 100,000

University of Michigan

1105 North University Room 4218
Ann Arbor,MI48109 		NONE PC A Feminist Framing of Fruitless: Maleness as a Suppression of Female Neural Programs. Principal Investigator: E. Josie Clowney 74,913

University of Michigan

109 Zina Pitcher Place
Ann Arbor,MI48109 		NONE PC Cellular Mechanisms Controlling Circadian Rythms. Principal Investigator: Swathi Yadlapalli 75,000

University of North Carolina - Chapel Hill

116 Manning Drive
Chapel Hill,NC27599 		NONE PC Elucidating the Neural Basis of Pain Unpleasantness: Circuits and New Therapeutics to End the Dual Epidemic of Chronic Pain and Opioid Addiction. Principal Investigator: Gregory Scherrer 100,000

University of Utah

50 N Medical Drive
Salt Lake City,UT84132 		NONE PC Neuropeptidergic Cortical Control of Social Isolation. Principal Investigator: Dr. Moriel Zelikowsky 75,000

University of Washington

850 Republican Street S441
Seattle,WA98109 		NONE GOV Massively parallel, high throughput engineering of optogenetic biosensors for neuronal signaling. Principal Investigator: Andre Berndt, Ph.D. 100,000

UT Southwestern Medical Center

6001 Forest Park Rd
Dallas,TX75214 		NONE GOV Understanding the Construction and Function of Glycinergic Post-Synaptic Assemblies. Principal Investigator: Weiwei Wang, Ph.D. 75,000

Yale University

333 Cedar St Department of Neurosci
ence PO Box 2
New Haven,CT06520 		NONE PC Mechanism and functions of repeat expansion self-exonization in C9orf72 ALS/FTD. Principal Investigator: Junjie Guo, Ph.D. 100,000

Yale University School of Medicine

333 Cedar St Department of Neurosci
ence PO Box 2
New Haven,CT06520 		NONE PC From Gut to Brain: Understanding the Propagation of Parkinson's Disease. Principal Investigator: Rui Chang & Sreeganga Chandra 100,000

California Institute of Technology

1200 EAST CALIFORNIA BLVD
PASADENA,CA91125 		NONE PC McKnight Pecot Fellowship 2023. Principal Investigator: Zinn, Dr. Kai, Ph.D. 16,500

Columbia University

3227 Broadway
New York,NY10027 		NONE PC McKnight Pecot Fellowship 2023. Principal Investigator: Behnia, Rudy, Ph.D. 16,500

Johns Hopkins University

3400 NORTH CHARLES STREET
Baltimore,MD21218 		NONE PC McKnight Pecot Fellowship 2023. Principal Investigator: Watanabe, Dr. Shigeki, Ph.D. 16,500

Texas State University Department of Psychology

601 UNIVERSITY DRIVE
San Marcos,TX78666 		NONE GOV McKnight Pecot Fellowship 2023. Principal Investigator: Westerberg, Carmen, Ph.D. 16,500

The Regents of the University of California

201 Gilman Hall UC Berkeley
Berkeley,CA94702 		NONE GOV McKnight Pecot Fellowship 2023. Principal Investigator: Isacoff, Dr. Ehud Y., Ph.D. 16,500
Total .................................right arrow 3a 3,207,413
bApproved for future payment

Albert Einstein College of Medicine
1300 Morris Park Ave Ste 402
New York,NY10461 		NONE PC Unravelling the mechanisms of synapse development, from molecules to behavior. Principal Investigator: Dr. Peri Kurshan 150,000

Brigham and Women's HospitalHarvard Medical School
60 Fenwood Rd Hale Building Room 70
02L
Boston,MA02115 		NONE PC The Neurobiology of Glioma: Understanding Malignant Neural Circuits Instructing Tumor Growth. Principal Investigator: Humsa Venkatesh,Ph.D. 300,000

Columbia University
3227 Broadway
New York,NY10027 		NONE PC Skin-brain axis for rewarding touch behaviors. Principal Investigator: Dr. Ishmail Abdus-Saboor 150,000

Columbia University
3227 Broadway
New York,NY10027 		NONE PC Neural Mechanisms of Courtship and Monogamy. Principal Investigator: Dr. Vikram Gadagkar 150,000

Columbia University
3227 Broadway
New York,NY10027 		NONE PC Cortical circuits for perceiving visual form. Principal Investigator: Dr. Yasmine El-Shamayleh 150,000

Fred Hutchinson Cancer Research Center
1100 Fairview Ave N PO Box 19024
Seattle,WA98109 		NONE PC Adipocyte-brain mitochondrial signaling and its impacts on brain function. Principal Investigator: Akhila Rajan,Ph.D. 300,000

Max Planck Florida Institute
1 Max Planck Way
Jupiter,FL33458 		NONE PC Synaptic mechanisms and network dynamics underlying motor learning. Principal Investigator: Dr. Hidehiko Inagaki 150,000

New York University
4 Washington Place Room 621
New York,NY10003 		NONE PC Modulation of striatal cells and synapses by dopamine movement signals. Principal Investigator: Dr. Tanya Sippy 150,000

Oregon Health & Science University
3181 SW Sam Jackson Park Road L623
Portland,OR97239 		NONE GOV Mechanosensation for guiding cellular morphology. Principal Investigator: Dr. Swetha Murthy 150,000

Stanford University
371 Jane Stanford Way
Stanford,CA94305 		NONE PC Machine Learning Methods for Discovering Structure in Neural and Behavioral Data. Principal Investigator: Dr. Scott Linderman 150,000

Stanford University School of Medicine
401 Quarry Rd
Palo Alto,CA94304 		NONE PC Neuron-to-OPC synapses in adaptive and maladaptive myelination. Principal Investigator: Juliet K. Knowles, MD, PhD 300,000

The Regents of the University of California
201 Gilman Hall UC Berkeley
Berkeley,CA94702 		NONE GOV Evolution of neural diversity and patterning in the visual system. Principal Investigator: Dr. Karthik Shekhar 150,000

University of Utah
50 N Medical Drive
Salt Lake City,UT84132 		NONE PC Neuropeptidergic Cortical Control of Social Isolation. Principal Investigator: Dr. Moriel Zelikowsky 150,000

Yale University
333 Cedar St Department of Neurosci
ence PO Box 2
New Haven,CT06520 		NONE PC Mechanism and functions of repeat expansion self-exonization in C9orf72 ALS/FTD. Principal Investigator: Junjie Guo, Ph.D. 300,000
Total ................................. right arrow 3b 2,700,000
Form 990-PF (2023)
Form 990-PF (2023)
Page 12
Part XV-A
Analysis of Income-Producing Activities
Enter gross amounts unless otherwise indicated. Unrelated business income Excluded by section 512, 513, or 514 (e)
Related or exempt
function income
(See instructions.)
1Program service revenue: (a)
Business code 		(b)
Amount 		(c)
Exclusion code 		(d)
Amount
a
b
c
d
e
f
gFees and contracts from government agencies          
2 Membership dues and assessments ....          
3 Interest on savings and temporary cash
investments ........... 		         
4 Dividends and interest from securities ....          
5 Net rental income or (loss) from real estate:
aDebt-financed property......          
bNot debt-financed property.....          
6 Net rental income or (loss) from personal property          
7 Other investment income .....          
8 Gain or (loss) from sales of assets other than
inventory ............ 		         
9 Net income or (loss) from special events:          
10 Gross profit or (loss) from sales of inventory          
11 Other revenue: a
b
c
d
e
12 Subtotal. Add columns (b), (d), and (e) .. 0 0 0
13Total. Add line 12, columns (b), (d), and (e)..................
13
0
(See worksheet in line 13 instructions to verify calculations.)
Part XV-B
Relationship of Activities to the Accomplishment of Exempt Purposes
Line No.
DownArrow 		Explain below how each activity for which income is reported in column (e) of Part XV-A contributed importantly to
the accomplishment of the foundation’s exempt purposes (other than by providing funds for such purposes). (See
instructions.)
Form 990-PF (2023)
Form 990-PF (2023)
Page 13
Part XVI
Information Regarding Transfers To and Transactions and Relationships With Noncharitable Exempt Organizations
1
Did the organization directly or indirectly engage in any of the following with any other organization described in section 501(c) (other than section 501(c)(3) organizations) or in section 527, relating to political organizations?
Yes
No
a
Transfers from the reporting foundation to a noncharitable exempt organization of:
(1) Cash...................................
1a(1)
 
No
(2) Other assets.................................
1a(2)
 
No
b
Other transactions:
(1) Sales of assets to a noncharitable exempt organization....................
1b(1)
 
No
(2) Purchases of assets from a noncharitable exempt organization..................
1b(2)
 
No
(3) Rental of facilities, equipment, or other assets.......................
1b(3)
 
No
(4) Reimbursement arrangements...........................
1b(4)
 
No
(5) Loans or loan guarantees.............................
1b(5)
 
No
(6) Performance of services or membership or fundraising solicitations................
1b(6)
 
No
c
Sharing of facilities, equipment, mailing lists, other assets, or paid employees..............
1c
 
No
d
If the answer to any of the above is "Yes," complete the following schedule. Column (b) should always show the fair market value
of the goods, other assets, or services given by the reporting foundation. If the foundation received less than fair market value
in any transaction or sharing arrangement, show in column (d) the value of the goods, other assets, or services received.
(a) Line No. (b) Amount involved (c) Name of noncharitable exempt organization (d) Description of transfers, transactions, and sharing arrangements
2a
Is the foundation directly or indirectly affiliated with, or related to, one or more tax-exempt organizations
described in section 501(c) (other than section 501(c)(3)) or in section 527? ...........
b
If "Yes," complete the following schedule.

(a) Name of organization (b) Type of organization (c) Description of relationship
Sign Here
Under penalties of perjury, I declare that I have examined this return, including accompanying schedules and statements, and to the best of my knowledge and belief, it is true, correct, and complete. Declaration of preparer (other than taxpayer) is based on all information of which preparer has any knowledge.
right arrow right arrow
May the IRS discuss this return
with the preparer shown below?
See instructions.
Signature of officer or trustee Date Title
Paid Preparer Use Only Print/Type preparer's name Preparer's Signature Date Check if self-
employed right arrow		 PTIN
Firm's name SmallBullet
 Firm's EIN SmallBullet
Firm's address SmallBullet


 Phone no.
Form 990-PF (2023)
Additional Data


Software ID: 23017437
Software Version: 2023v5.1


Form 990PF - Special Condition Description:
Special Condition Description
Schedule B
(Form 990)
Department of the Treasury
Internal Revenue Service
Schedule of Contributors

Arrow Bullet Attach to Form 990, 990-EZ, or 990-PF.
Arrow Bullet Go to www.irs.gov/Form990 for the latest information.
OMB No. 1545-0047
2023
Name of the organization
THE MCKNIGHT ENDOWMENT FUND FOR NEUROSCIENCE
 
Employer identification number

41-1563321
Organization type (check one):
Filers of:
Section:
Form 990 or 990-EZ






Form 990-PF




Check if your organization is covered by the General Rule or a Special Rule.  
Note: Only a section 501(c)(7), (8), or (10) organization can check boxes for both the General Rule and a Special Rule. See instructions.
General Rule
Special Rules
......... Arrow Bullet $  
Caution: An organization that isn't covered by the General Rule and/or the Special Rules doesn't file Schedule B (Form 990,
990-EZ, or 990-PF), but it must answer “No” on Part IV, line 2, of its Form 990; or check the box on line H of its Form 990-EZ
or on its Form 990PF, Part I, line 2, to certify that it doesn't meet the filing requirements of Schedule B (Form 990,
990-EZ, or 990-PF).
For Paperwork Reduction Act Notice, see the Instructions
for Form 990, 990-EZ, or 990-PF.
Cat. No. 30613XSchedule B (Form 990) (2023)
Schedule B (Form 990) (2023) Page 2
Name of organization
THE MCKNIGHT ENDOWMENT FUND FOR NEUROSCIENCE
  		Employer identification number
41-1563321
Part I
Contributors
Contributors (see instructions). Use duplicate copies of Part I if additional space is needed.
(a)
No.		 (b)
Name, address, and ZIP + 4		 (c)
Total contributions		 (d)
Type of contribution
1
THE MCKNIGHT FOUNDATION
 
710 S 2ND ST STE 400
 
MINNEAPOLIS, MN554012290

$ 3,800,550


(Complete Part II for noncash contributions.)
(a)
No.		 (b)
Name, address, and ZIP + 4		 (c)
Total contributions		 (d)
Type of contribution
 
 
 
 

$  


(Complete Part II for noncash contributions.)
(a)
No.		 (b)
Name, address, and ZIP + 4		 (c)
Total contributions		 (d)
Type of contribution
 
 
 
 

$  


(Complete Part II for noncash contributions.)
(a)
No.		 (b)
Name, address, and ZIP + 4		 (c)
Total contributions		 (d)
Type of contribution
 
 
 
 

$  


(Complete Part II for noncash contributions.)
(a)
No.		 (b)
Name, address, and ZIP + 4		 (c)
Total contributions		 (d)
Type of contribution
 
 
 
 

$  


(Complete Part II for noncash contributions.)
(a)
No.		 (b)
Name, address, and ZIP + 4		 (c)
Total contributions		 (d)
Type of contribution
 
 
 
 

$  


(Complete Part II for noncash contributions.)
Schedule B (Form 990) (2023)
Schedule B (Form 990) (2023)
Page 3
Name of organization
THE MCKNIGHT ENDOWMENT FUND FOR NEUROSCIENCE
  		Employer identification number

41-1563321
Part II
Noncash Property (see instructions). Use duplicate copies of Part II if additional space is needed.
(a)
No. from Part I 		(b)
Description of noncash property given 		(c)
FMV (or estimate)
(See instructions) 		(d)
Date received
 
$    
(a)
No. from Part I 		(b)
Description of noncash property given 		(c)
FMV (or estimate)
(See instructions) 		(d)
Date received
 
$    
(a)
No. from Part I 		(b)
Description of noncash property given 		(c)
FMV (or estimate)
(See instructions) 		(d)
Date received
 
$    
(a)
No. from Part I 		(b)
Description of noncash property given 		(c)
FMV (or estimate)
(See instructions) 		(d)
Date received
 
$    
(a)
No. from Part I 		(b)
Description of noncash property given 		(c)
FMV (or estimate)
(See instructions) 		(d)
Date received
 
$    
(a)
No. from Part I 		(b)
Description of noncash property given 		(c)
FMV (or estimate)
(See instructions) 		(d)
Date received
 
$    
Schedule B (Form 990) (2023)
Schedule B (Form 990) (2023)
Page 4
Name of organization
THE MCKNIGHT ENDOWMENT FUND FOR NEUROSCIENCE
  		Employer identification number

41-1563321
Part III
Exclusively religious, charitable, etc., contributions to organizations described in section 501(c)(7), (8), or (10) that total more than $1,000 for the year from any one contributor. Complete columns (a) through (e) and the following line entry. For organizations completing Part III, enter the total of exclusively religious, charitable, etc., contributions of $1,000 or less for the year. (Enter this information once. See instructions.) Arrow Bullet$  
Use duplicate copies of Part III if additional space is needed.
(a)
No. from Part I		 (b) Purpose of gift (c) Use of gift (d) Description of how gift is held
 
(e) Transfer of gift
Transferee's name, address, and ZIP 4 Relationship of transferor to transferee
 
 
     
 
(a)
No. from Part I		 (b) Purpose of gift (c) Use of gift (d) Description of how gift is held
 
(e) Transfer of gift
Transferee's name, address, and ZIP 4 Relationship of transferor to transferee
 
 
     
 
(a)
No. from Part I		 (b) Purpose of gift (c) Use of gift (d) Description of how gift is held
 
(e) Transfer of gift
Transferee's name, address, and ZIP 4 Relationship of transferor to transferee
 
 
     
 
(a)
No. from Part I		 (b) Purpose of gift (c) Use of gift (d) Description of how gift is held
 
(e) Transfer of gift
Transferee's name, address, and ZIP 4 Relationship of transferor to transferee
 
 
     
 
Schedule B (Form 990) (2023)
Additional Data


Software ID: 23017437
Software Version: 2023v5.1

TY 2023 AccountingFeesSchedule
Name:
THE MCKNIGHT ENDOWMENT FUND FOR NEUROSCIENCE
EIN:
41-1563321
Software ID:
23017437
Software Version:
2023v5.1
Category Amount Net Investment Income Adjusted Net Income Disbursements for Charitable Purposes
PROFESSIONAL FEES 9,885     9,885

TY 2023 GeneralExplanationAttachment
Name:
THE MCKNIGHT ENDOWMENT FUND FOR NEUROSCIENCE
EIN:
41-1563321
Software ID:
23017437
Software Version:
2023v5.1
Identifier Return Reference Explanation
ANNUAL CONFERENCE FORM 990-PF, PART VIII-A In June 2023, the McKnight Conference on Neuroscience was held its annual conference on neuroscience that was attended by 91 neuroscientists, members of the MEFN Board of Directors, the Awards Selection Committee, and 3 Doupe Fellows, and other invited guests. 14 McKnight award recipients and 6 guest speakers presented the findings of their brain research projects over the course of the June weekend. Special lecture topics included: "SYNAPSES LOST AND FOUND IN DEVELOPMENT AND ALZHEIMER'S DISEASE," PRESENTED BY CARLA SHATZ; "DISCOVERING AND REGULATING BRAIN NETWORKS UNDERLYING EMOTION," PRESENTED BY KAFUI DZIRASA; AND "UPDATE ON THE NIH BRAIN INITIATIVE," PRESENTED BY NIH BRAIN INITIATIVE DIRECTOR JOHN NGAI. Brain Disease Workshop: "AUTISM SPECTRUM DISORDERS INCLUDED RESEARCHERS DRS. SHAFALI SPURLING JESTE (UNIVERSITY OF SOUTHERN CALIFORNIA), AMI KLIN (EMORY UNIVERSITY), AND LOREN FRANK (UNIVERSITY OF CALIFORNIA SAN FRANCISCO). Other sessions included three (3) session of award recipient scientific speaking presentations, a technology workshop, and a technology demonstration. Each presentation included a 15 minutes question and answer session so that the conference audience benefited from an open discussion of the research works presented. In addition, the technology demonstration was interactive and included open discussions. The McKnight Conference on Neuroscience provides a forum for: 1) sharing of research developments by and between McKnight awardees through the formal presentations; 2) sharing of research work in informal discussions; and 3) monitoring by the board of directors and review committee members of the research work being supported by the McKnight Endowment Fund for Neuroscience. The next McKnight Conference on Neuroscience is scheduled to be held June 7-10, 2024, in Aspen, CO. Fourteen recent recipients of a McKnight award and five guest speakers will present the findings of their brain research projects.
AWARDS FORM 990-PF, PART XIV, LINE 2B The McKnight Endowment Fund for Neuroscience is an independent charitable organization established by The McKnight Foundation to carry out the intention of its founder, William L. McKnight (1887-1979). Mr. McKnight, who led the 3M company for three decades, had a personal interest in memory and its diseases and set aside part of his legacy to bring hope to those suffering from brain injury or disease and cognitive impairment. The Endowment Fund fulfills this mission by supporting innovative research in neuroscience through three competitive annual awards. The awards complement each other to support both young and established neuroscientists and to encourage interdisciplinary collaboration. Each in a different way, the three programs seek out investigators whose research shows promise in bringing society closer to preventions, treatments, and cures for many devastating diseases. Research supported by the Endowment Fund has furthered understanding of Alzheimer's disease, Parkinson's disease, spinal cord injuries, and many other cognitive impairments. In 2021, the Endowment Fund created a Fellowship for McKnight awardees to hire an undergraduate student from a community underrepresented in neuroscience. The Endowment Fund is led by a board of eminent neuroscientists, with administrative support from the McKnight Foundation. Each award has its own selection committee, also made up of prominent scientists. The committee recommends awardees, and the board has the final approval. McKnight Scholar Awards The McKnight Scholar Awards encourage neuroscientists in the early stages of their careers to focus on critical problems in brain science. These awards support young scientists who hold a M.D. and/or Ph.D. degree, who have completed formal postdoctoral training, and who demonstrate a commitment to neuroscience. The Endowment Fund especially seeks applicants who demonstrate an interest in solving important problems in relevant areas of neuroscience, including the translation of basic research to clinical neuroscience. For descriptions of previous awards, please go to the Endowment Fund website. Each year, up to ten Scholars are selected to receive three years of support at $75,000 per year. Funds may be used for direct costs in any way that will facilitate development of the Scholar's research program. Scholars must have authorization from the home institution to work in the U.S. and must hold full time appointments at the rank of assistant professor at their sponsoring institution; scientists holding other titles such as research assistant professor, adjunct assistant professor, assistant professor research track, visiting professor, or instructor are not eligible. If the host institution does not use professorial titles, a letter from a senior institutional official (e.g., Dean or Director of Research) must confirm that the applicant has his/her own dedicated institutional resources, laboratory space, and/or facilities. Application materials are due in early January and can be uploaded by accessing the online URL set up for this purpose. Each applicant must ensure that four letters of reference are submitted to an email account; these letters are an integral part of the application. Awards are announced in June and begin on July 1. McKnight Neurobiology of Brain Disorders Award The Neurobiology of Brain Disorder Awards, support neuroscientists who are working to apply the knowledge achieved through basic or clinical research to human brain disorders and who address the biology and mechanisms of neurological and psychiatric disorders. They are designed to stimulate innovative approaches that might lead to therapies and cures. Competitive projects would include those that provide mechanistic insights into neurological functions at the synaptic, cellular, molecular, genetic, or behavioral level across different species, including humans and vertebrate and invertebrate model organisms, and that incorporate fundamentally new approaches that provide potential paths for therapeutic interventions. Collaborative and cross-disciplinary applications are encouraged. For descriptions of previous awards, please go to the Endowment Fund website. The first step is to submit a two-page letter of intent describing the project and how the research will be applied to improving the understanding of a brain disorder or disease. Investigators must have authorization from the home institution to work in the U.S. and must hold full time appointments at the rank of assistant professor or higher at the sponsoring institution; scientists holding other titles such as research professor, adjunct professor, professor research track, visiting professor, or instructor are not eligible. If the host institution does not use professorial titles, a letter from a senior institutional official (e.g., Dean or Director of Research) must confirm that the applicant has his/her own dedicated institutional resources, laboratory space, and/or facilities. Funds may be used toward a variety of research activities, except the recipient's salary. The selection committee will invite a few applicants to submit detailed proposals, from which up to four awards will be selected. Each provides $100,000 annually for three years. Letters of intent are due in November and can be uploaded by accessing the online URL set up for this purpose. Awards are announced in June and begin in August of the following year. McKnight Matthew Pecot Fellowship The McKnight Pecot Fellowship, created in 2021, is named in honor of McKnight Scholar Awardee Matthew Pecot, who died in 2019. Matthew was a brilliant BIPOC neuroscientist at Harvard Medical School and a 2017 McKnight Scholar Awardee. He received his McKnight award for his work on identifying molecular principles underlying synaptic specificity. Matthew's McKnight work has contributed to identifying defects in neural connectivity, which underlie many neural psychiatric diseases. Up to six current McKnight Endowment Fund awardees are selected to receive $16,500 to hire an underrepresented college student to perform research in the McKnight awardee's lab. In addition to supervising the Fellow's research activities, the McKnight awardee will provide mentorship and networking opportunities for the Fellow. Additionally, the Fellow will be invited to the McKnight Endowment Fund annual conference. The Pecot Fellowship is open to all former and current McKnight neuroscientists. The nomination application includes a recommendation from the McKnight awardee; an essay on a scientific topic by the undergraduate who is being nominated; and the undergraduate's resume. Nominations are submitted in February/March and awardees are notified in April/May. A subcommittee of McKnight Endowment for Neuroscience board members selects the awards.

TY 2023 OtherExpensesSchedule
Name:
THE MCKNIGHT ENDOWMENT FUND FOR NEUROSCIENCE
EIN:
41-1563321
Software ID:
23017437
Software Version:
2023v5.1
Description Revenue and Expenses per Books Net Investment Income Adjusted Net Income Disbursements for Charitable Purposes
MISCELLANEOUS EXPENSE 21     21
COMMUNICATION EXPENSE 6,386     6,386
COMPUTER SERVICES 13,267     13,267


TY 2023 OtherProfessionalFeesSchedule
Name:
THE MCKNIGHT ENDOWMENT FUND FOR NEUROSCIENCE
EIN:
41-1563321
Software ID:
23017437
Software Version:
2023v5.1
Category Amount Net Investment Income Adjusted Net Income Disbursements for Charitable Purposes
ADMINISTRATIVE SERVICE FEES 100,000     100,000
COMMITTEE FEES 32,000     32,000