TY 2024 Form 990

(A) Name and title	(B) Average hours per week (list any hours for related organizations below dotted line)	(C) Position (do not check more than one box, unless person is both an officer and a director/trustee)	(E) Reportable compensation from related organizations (W-2/1099-MISC/1099-NEC)
(1) ANDREW SCHMIDT MD...................................................................... DIRECTOR/PHYSICIAN (UNTIL 6/24)	4.90 ................. 27.10	X		0	608,540	52,155
(2) MICHAEL PUSKARICH MD MS...................................................................... DIRECTOR/PHYSICIAN	7.10 ................. 30.90	X		0	513,475	60,396
(3) MEGHAN WALSH MD MPH FACP...................................................................... DIRECTOR/HHS - CARO	0.20 ................. 39.80	X		0	475,382	64,536
(4) KIRSTEN L JOHANSEN MD...................................................................... PRESIDENT/INVESTIGATOR	29.90 ................. 11.10	X	X	0	479,088	58,740
(5) THERESA PESCH RN...................................................................... HHS VP OF PHILANTHROPHY	0.10 ................. 39.90	X		0	431,214	62,880
(6) ERIC LING MD MBA MA...................................................................... DIRECTOR/HHS - CHIEF OF MEDICAL OFFICER	0.10 ................. 39.90	X		0	316,146	46,350
(7) ANNE FROSCH MD...................................................................... DIRECTOR/INVESTIGATOR	27.60 ................. 12.40	X		0	279,337	53,536
(8) WARREN MCKINNEY PHD...................................................................... DIRECTOR/VP FOR EQUITY IN RESEARCH/INVESTIGATOR	40.00 ................. 0.00	X	X	117,100	0	24,654
(9) EDWARD P EHLINGER MD MSPH...................................................................... DIRECTOR	0.10 ................. 0.00	X		0	0	0
(10) GOPAL KHANNA MBA...................................................................... DIRECTOR	0.10 ................. 0.00	X		0	0	0
(11) SIMON SHANNON MBA PHD...................................................................... DIRECTOR	0.10 ................. 0.00	X		0	0	0
(12) PRAT VERMA MBA MS...................................................................... DIRECTOR	0.10 ................. 0.00	X		0	0	0
(13) RICHARD KING MD PHD...................................................................... BOARD CHAIR (UNTIL 4/24)	0.20 ................. 0.00	X	X	0	0	0
(14) CONNIE DELANEY PHD RN FAAN...................................................................... BOARD CHAIR	0.20 ................. 0.00	X	X	0	0	0
(15) MIAJA CASSIDY JD CHC CCEP...................................................................... BOARD VICE CHAIR	0.20 ................. 0.00	X	X	0	0	0
(16) SERAFIN SAMSON MBA MS...................................................................... SECRETARY/TREASURER	0.50 ................. 0.00	X	X	0	0	0
(17) MARK WILLMERT CPA INACTIVE...................................................................... HHF/HHRI - VP OF FINANCE	23.70 ................. 16.30		X	0	209,584	33,166

(A) Name and business address	(B) Description of services	(C) Compensation
HENNEPIN HEALTHCARE SYSTEM 701 PARK AVENUE MINNEAPOLIS,MN55415	PHYSICIAN PROFESSIONAL RESEARCH	4,426,996
MONASH UNIVERSITY VICTORIA 3800 MELBOURNE,VIC3004 AS	MEDICINE, NURSING, AND RESEARCH	3,518,531
UNIVERSITY OF MINNESOTA 200 OAK STREET SE MINNEAPOLIS,MN55455	PHYSICIAN PROFESSIONAL RESEARCH	3,204,737
HEALTHPARTNERS INSTITUTE 8170 33RD AVENUE SOUTH BLOOMINGTON,MN55425	PHYSICIAN PROFESSIONAL RESEARCH	1,906,070
MAYO CLINIC 200 1ST STREET SW ROCHESTER,MN55905	PHYSICIAN PROFESSIONAL RESEARCH	892,601
2 Total number of independent contractors (including but not limited to those listed above) who received more than $100,000 of compensation from the organization 39

- TIN:

SCHEDULE A
(Form 990)

Department of the Treasury
Internal Revenue Service

Public Charity Status and Public Support

Complete if the organization is a section 501(c)(3) organization or a section 4947(a)(1) nonexempt charitable trust.
right arrow

Attach to Form 990 or Form 990-EZ.
right arrow

Go to www.irs.gov/Form990 for instructions and the latest information.

OMB No. 1545-0047

2024

Open to Public
Inspection

Name of the organization

HENNEPIN HEALTHCARE RESEARCH INSTITUTE

Employer identification number

41-1677920

Part I

Reason for Public Charity Status (All organizations must complete this part.) See instructions.

The organization is not a private foundation because it is: (For lines 1 through 12, check only one box.)

A church, convention of churches, or association of churches described in section 170(b)(1)(A)(i).

A school described in section 170(b)(1)(A)(ii). (Attach Schedule E (Form 990).)

A hospital or a cooperative hospital service organization described in section 170(b)(1)(A)(iii).

A medical research organization operated in conjunction with a hospital described in section 170(b)(1)(A)(iii). Enter the hospital's name, city, and state:

An organization operated for the benefit of a college or university owned or operated by a governmental unit described in section 170(b)(1)(A)(iv). (Complete Part II.)

A federal, state, or local government or governmental unit described in section 170(b)(1)(A)(v).

An organization that normally receives a substantial part of its support from a governmental unit or from the general public described in section 170(b)(1)(A)(vi). (Complete Part II.)

A community trust described in section 170(b)(1)(A)(vi). (Complete Part II.)

An agricultural research organization described in 170(b)(1)(A)(ix) operated in conjunction with a land-grant college or university or a non-land grant college of agriculture. See instructions. Enter the name, city, and state of the college or university:

An organization that normally receives: (1) more than 33 1/3% of its support from contributions, membership fees, and gross receipts from activities related to its exempt functions—subject to certain exceptions, and (2) no more than 33 1/3% of its support from gross investment income and unrelated business taxable income (less section 511 tax) from businesses acquired by the organization after June 30, 1975. See section 509(a)(2). (Complete Part III.)

An organization organized and operated exclusively to test for public safety. See section 509(a)(4).

An organization organized and operated exclusively for the benefit of, to perform the functions of, or to carry out the purposes of one or more publicly supported organizations described in section 509(a)(1) or section 509(a)(2). See section 509(a)(3). Check the box on lines 12a through 12d that describes the type of supporting organization and complete lines 12e, 12f, and 12g.

Type I. A supporting organization operated, supervised, or controlled by its supported organization(s), typically by giving the supported organization(s) the power to regularly appoint or elect a majority of the directors or trustees of the supporting organization. You must complete Part IV, Sections A and B.

Type II. A supporting organization supervised or controlled in connection with its supported organization(s), by having control or management of the supporting organization vested in the same persons that control or manage the supported organization(s). You must complete Part IV, Sections A and C.

Type III functionally integrated. A supporting organization operated in connection with, and functionally integrated with, its supported organization(s) (see instructions). You must complete Part IV, Sections A, D, and E.

Type III non-functionally integrated. A supporting organization operated in connection with its supported organization(s) that is not functionally integrated. The organization generally must satisfy a distribution requirement and an attentiveness requirement (see instructions). You must complete Part IV, Sections A and D, and Part V.

Check this box if the organization received a written determination from the IRS that it is a Type I, Type II, Type III functionally integrated, or Type III non-functionally integrated supporting organization.

Enter the number of supported organizations ...............................

Provide the following information about the supported organization(s).

(i) Name of supported organization	(ii) EIN	(iv) Is the organization listed in your governing document?		(v) Amount of monetary support (see instructions)	(vi) Amount of other support (see instructions)
(i) Name of supported organization	(ii) EIN	Yes	No	(v) Amount of monetary support (see instructions)	(vi) Amount of other support (see instructions)


Total

For Paperwork Reduction Act Notice, see the Instructions for
Form 990 or 990-EZ.

Cat. No. 11285F

Schedule A (Form 990) 2024

Page 2

Part II

Support Schedule for Organizations Described in Sections 170(b)(1)(A)(iv) and 170(b)(1)(A)(vi)
(Complete only if you checked the box on line 5, 7, or 8 of Part I or if the organization failed to qualify under Part III. If the organization failed to qualify under the tests listed below, please complete Part III.)

Section A. Public Support

Calendar year (or fiscal year beginning in)		(a) 2020	(b) 2021	(c) 2022	(d) 2023	(e) 2024	(f) Total
1	Gifts, grants, contributions, and membership fees received. (Do not include any "unusual grant.") ..	37,708,720	45,253,547	54,473,378	55,200,822	52,551,531	245,187,998
2	Tax revenues levied for the organization's benefit and either paid to or expended on its behalf ....
3	The value of services or facilities furnished by a governmental unit to the organization without charge..
4	Total. Add lines 1 through 3	37,708,720	45,253,547	54,473,378	55,200,822	52,551,531	245,187,998
5	The portion of total contributions by each person (other than a governmental unit or publicly supported organization) included on line 1 that exceeds 2% of the amount shown on line 11, column (f) ..						3,641,882
6	Public support. Subtract line 5 from line 4.						241,546,116

Section B. Total Support

Calendar year (or fiscal year beginning in)		(a) 2020	(b) 2021	(c) 2022	(d) 2023	(e) 2024	(f) Total
7	Amounts from line 4..	37,708,720	45,253,547	54,473,378	55,200,822	52,551,531	245,187,998
8	Gross income from interest, dividends, payments received on securities loans, rents, royalties and income from similar sources...	952,588	2,183,028	1,332,737	1,700,462	2,173,495	8,342,310
9	Net income from unrelated business activities, whether or not the business is regularly carried on..
10	Other income. Do not include gain or loss from the sale of capital assets (Explain in Part VI.)..
11	Total support. Add lines 7 through 10						253,530,308

Gross receipts from related activities, etc. (see instructions) ..................

First 5 years. If the Form 990 is for the organization's first, second, third, fourth, or fifth tax year as a section 501(c)(3) organization, check this box and stop here ........................................ right arrow

Section C. Computation of Public Support Percentage

Public support percentage for 2024 (line 6, column (f) divided by line 11, column (f)) .........

95.270 %

Public support percentage for 2023 Schedule A, Part II, line 14 ...............

94.580 %

16a

33 1/3% support test—2024. If the organization did not check the box on line 13, and line 14 is 33 1/3% or more, check this box
and stop here. The organization qualifies as a publicly supported organization ....................... right arrow

33 1/3% support test—2023. If the organization did not check a box on line 13 or 16a, and line 15 is 33 1/3% or more, check this
box and stop here. The organization qualifies as a publicly supported organization ..................... right arrow

17a

10%-facts-and-circumstances test—2024. If the organization did not check a box on line 13, 16a, or 16b, and line 14 is 10% or more, and if the organization meets the "facts-and-circumstances" test, check this box and stop here. Explain in Part VI how the organization meets the "facts-and-circumstances" test. The organization qualifies as a publicly supported organization ............ right arrow

10%-facts-and-circumstances test—2023. If the organization did not check a box on line 13, 16a, 16b, or 17a, and line 15 is 10% or more, and if the organization meets the "facts-and-circumstances" test, check this box and stop here. Explain in Part VI how the organization meets the "facts-and-circumstances" test. The organization qualifies as a publicly supported organization ............ right arrow

Private foundation. If the organization did not check a box on line 13, 16a, 16b, 17a, or 17b, check this box and see
instructions ..................................................... right arrow

Schedule A (Form 990) 2024

Page 3

Part III

Support Schedule for Organizations Described in Section 509(a)(2)
(Complete only if you checked the box on line 10 of Part I or if the organization failed to qualify under Part II. If the organization fails to qualify under the tests listed below, please complete Part II.)

Section A. Public Support

Calendar year (or fiscal year beginning in)		(a) 2020	(b) 2021	(c) 2022	(d) 2023	(e) 2024	(f) Total
1	Gifts, grants, contributions, and membership fees received. (Do not include any "unusual grants.") .
2	Gross receipts from admissions, merchandise sold or services performed, or facilities furnished in any activity that is related to the organization's tax-exempt purpose
3	Gross receipts from activities that are not an unrelated trade or business under section 513 .....
4	Tax revenues levied for the organization's benefit and either paid to or expended on its behalf...
5	The value of services or facilities furnished by a governmental unit to the organization without charge
6	Total. Add lines 1 through 5
7a	Amounts included on lines 1, 2, and 3 received from disqualified persons
b	Amounts included on lines 2 and 3 received from other than disqualified persons that exceed the greater of $5,000 or 1% of the amount on line 13 for the year.
c	Add lines 7a and 7b..
8	Public support. (Subtract line 7c from line 6.)

Section B. Total Support

Calendar year (or fiscal year beginning in)		(a) 2020	(b) 2021	(c) 2022	(d) 2023	(e) 2024	(f) Total
9	Amounts from line 6...
10a	Gross income from interest, dividends, payments received on securities loans, rents, royalties and income from similar sources..
b	Unrelated business taxable income (less section 511 taxes) from businesses acquired after June 30, 1975.
c	Add lines 10a and 10b.
11	Net income from unrelated business activities not included on line 10b, whether or not the business is regularly carried on.
12	Other income. Do not include gain or loss from the sale of capital assets (Explain in Part VI.) ..
13	Total support. (Add lines 9, 10c, 11, and 12.)..

First 5 years. If the Form 990 is for the organization's first, second, third, fourth, or fifth tax year as a section 501(c)(3) organization, check this box and stop here................................................. right arrow

Section C. Computation of Public Support Percentage

Public support percentage for 2024 (line 8, column (f) divided by line 13, column (f)) .........

Public support percentage from 2023 Schedule A, Part III, line 15 ...............

Section D. Computation of Investment Income Percentage

Investment income percentage for 2024 (line 10c, column (f) divided by line 13, column (f)) ......

Investment income percentage from 2023 Schedule A, Part III, line 17 .............

19a

33 1/3% support tests-2024. If the organization did not check the box on line 14, and line 15 is more than 33 1/3%, and line 17 is not more than 33 1/3%, check this box and stop here. The organization qualifies as a publicly supported organization ....... right arrow

33 1/3 % support tests—2023. If the organization did not check a box on line 14 or line 19a, and line 16 is more than 33 1/3% and line 18 is not more than 33 1/3%, check this box and stop here. The organization qualifies as a publicly supported organization ..... right arrow

Private foundation. If the organization did not check a box on line 14, 19a, or 19b, check this box and see instructions .... right arrow

Schedule A (Form 990) 2024

Page 4

Part IV

Supporting Organizations

(Complete only if you checked a box on line 12 of Part I. If you checked box 12a, of Part I, complete Sections A and B. If you checked box 12b, of Part I, complete Sections A and C. If you checked box 12c, of Part I, complete Sections A, D, and E. If you checked box12d, of Part I, complete Sections A and D, and complete Part V.)

Section A. All Supporting Organizations

Yes

Are all of the organization’s supported organizations listed by name in the organization’s governing documents?
If "No," describe in Part VI how the supported organizations are designated. If designated by class or purpose,
describe the designation. If historic and continuing relationship, explain.

Did the organization have any supported organization that does not have an IRS determination of status under section 509(a)(1) or (2)? If "Yes," explain in Part VI how the organization determined that the supported organization was described in section 509(a)(1) or (2).

Did the organization have a supported organization described in section 501(c)(4), (5), or (6)? If "Yes," answer lines 3b and 3c below.

Did the organization confirm that each supported organization qualified under section 501(c)(4), (5), or (6) and satisfied the public support tests under section 509(a)(2)? If "Yes," describe in Part VI when and how the organization made the determination.

Did the organization ensure that all support to such organizations was used exclusively for section 170(c)(2)(B) purposes? If "Yes," explain in Part VI what controls the organization put in place to ensure such use.

Was any supported organization not organized in the United States ("foreign supported organization")? If “Yes” and if you checked box 12a or 12b in Part I, answer lines 4b and 4c below.

Did the organization have ultimate control and discretion in deciding whether to make grants to the foreign supported organization? If “Yes,” describe in Part VI how the organization had such control and discretion despite being controlled or supervised by or in connection with its supported organizations.

Did the organization support any foreign supported organization that does not have an IRS determination under sections 501(c)(3) and 509(a)(1) or (2)? If “Yes,” explain in Part VI what controls the organization used to ensure that all support to the foreign supported organization was used exclusively for section 170(c)(2)(B) purposes.

Did the organization add, substitute, or remove any supported organizations during the tax year? If “Yes,” answer lines 5b and 5c below (if applicable). Also, provide detail in Part VI, including (i) the names and EIN numbers of the supported organizations added, substituted, or removed; (ii) the reasons for each such action; (iii) the authority under the organization's organizing document authorizing such action; and (iv) how the action was accomplished (such as by amendment to the organizing document).

Type I or Type II only. Was any added or substituted supported organization part of a class already designated in the organization's organizing document?

Substitutions only. Was the substitution the result of an event beyond the organization's control?

Did the organization provide support (whether in the form of grants or the provision of services or facilities) to anyone other than (i) its supported organizations, (ii) individuals that are part of the charitable class benefited by one or more of its supported organizations, or (iii) other supporting organizations that also support or benefit one or more of the filing organization’s supported organizations? If “Yes,” provide detail in Part VI.

Did the organization provide a grant, loan, compensation, or other similar payment to a substantial contributor (defined in section 4958(c)(3)(C)), a family member of a substantial contributor, or a 35% controlled entity with regard to a substantial contributor? If “Yes,” complete Part I of Schedule L (Form 990) .

Did the organization make a loan to a disqualified person (as defined in section 4958) not described on line 7? If “Yes,” complete Part I of Schedule L (Form 990).

Was the organization controlled directly or indirectly at any time during the tax year by one or more disqualified persons, as defined in section 4946 (other than foundation managers and organizations described in section 509(a)(1) or (2))? If “Yes,” provide detail in Part VI.

Did one or more disqualified persons (as defined on line 9a) hold a controlling interest in any entity in which the supporting organization had an interest? If “Yes,” provide detail in Part VI.

Did a disqualified person (as defined on line 9a) have an ownership interest in, or derive any personal benefit from, assets in which the supporting organization also had an interest? If “Yes,” provide detail in Part VI.

10a

Was the organization subject to the excess business holdings rules of section 4943 because of section 4943(f) (regarding certain Type II supporting organizations, and all Type III non-functionally integrated supporting organizations)? If “Yes,” answer line 10b below.

10a

Did the organization have any excess business holdings in the tax year? (Use Schedule C, Form 4720, to determine whether the organization had excess business holdings).

10b

Schedule A (Form 990) 2024

Page 5

Part IV

Supporting Organizations (continued)

Yes

Has the organization accepted a gift or contribution from any of the following persons?

A person who directly or indirectly controls, either alone or together with persons described on lines 11b and 11c below, the governing body of a supported organization?

11a

A family member of a person described on 11a above?

11b

A 35% controlled entity of a person described on line 11a or 11b above? If “Yes” to 11a, 11b, or 11c, provide detail in Part VI.

11c

Section B. Type I Supporting Organizations

Yes

Did the officers, directors, trustees, or membership of one or more supported organizations have the power to regularly appoint or elect at least a majority of the organization’s directors or trustees at all times during the tax year? If “No,” describe in Part VI how the supported organization(s) effectively operated, supervised, or controlled the organization’s activities. If the organization had more than one supported organization, describe how the powers to appoint and/or remove directors or trustees were allocated among the supported organizations and what conditions or restrictions, if any, applied to such powers during the tax year.

Did the organization operate for the benefit of any supported organization other than the supported organization(s) that operated, supervised, or controlled the supporting organization? If “Yes,” explain in Part VI how providing such benefit carried out the purposes of the supported organization(s) that operated, supervised or controlled the supporting organization.

Section C. Type II Supporting Organizations

Yes

Were a majority of the organization’s directors or trustees during the tax year also a majority of the directors or trustees of each of the organization’s supported organization(s)? If “No,” describe in Part VI how control or management of the supporting organization was vested in the same persons that controlled or managed the supported organization(s).

Section D. All Type III Supporting Organizations

Yes

Did the organization provide to each of its supported organizations, by the last day of the fifth month of the organization’s tax year, (i) a written notice describing the type and amount of support provided during the prior tax year, (ii) a copy of the Form 990 that was most recently filed as of the date of notification, and (iii) copies of the organization’s governing documents in effect on the date of notification, to the extent not previously provided?

Were any of the organization’s officers, directors, or trustees either (i) appointed or elected by the supported organization(s) or (ii) serving on the governing body of a supported organization? If "No," explain in Part VI how the organization maintained a close and continuous working relationship with the supported organization(s).

By reason of the relationship described in line 2 above, did the organization’s supported organizations have a significant voice in the organization’s investment policies and in directing the use of the organization’s income or assets at all times during the tax year? If "Yes," describe in Part VI the role the organization’s supported organizations played in this regard.

Section E. Type III Functionally-Integrated Supporting Organizations

Check the box next to the method that the organization used to satisfy the Integral Part Test during the year (see instructions):

The organization satisfied the Activities Test. Complete line 2 below.

The organization is the parent of each of its supported organizations. Complete line 3 below.

The organization supported a governmental entity. Describe in Part VI how you supported a government entity (see instructions)

Activities Test. Answer lines 2a and 2b below.

Yes

Did substantially all of the organization’s activities during the tax year directly further the exempt purposes of the supported organization(s) to which the organization was responsive? If "Yes," then in Part VI identify those supported organizations and explain how these activities directly furthered their exempt purposes, how the organization was responsive to those supported organizations, and how the organization determined that these activities constituted substantially all of its activities.

Did the activities described on line 2a, above constitute activities that, but for the organization’s involvement, one or more of the organization’s supported organization(s) would have been engaged in? If "Yes," explain in Part VI the reasons for the organization’s position that its supported organization(s) would have engaged in these activities but for the organization’s involvement.

Parent of Supported Organizations. Answer lines 3a and 3b below.

Did the organization have the power to regularly appoint or elect a majority of the officers, directors, or trustees of each of the supported organizations?If "Yes" or "No", provide details in Part VI.

Did the organization exercise a substantial degree of direction over the policies, programs and activities of each of its supported organizations? If "Yes," describe in Part VI. the role played by the organization in this regard.

Schedule A (Form 990) 2024

Page 6

Part V

Type III Non-Functionally Integrated 509(a)(3) Supporting Organizations

Check here if the organization satisfied the Integral Part Test as a qualifying trust on Nov. 20, 1970 (explain in Part VI). See instructions. All other Type III non-functionally integrated supporting organizations must complete Sections A through E.

	Section A - Adjusted Net Income		(A) Prior Year	(B) Current Year (optional)
1	Net short-term capital gain	1
2	Recoveries of prior-year distributions	2
3	Other gross income (see instructions)	3
4	Add lines 1 through 3	4
5	Depreciation and depletion	5
6	Portion of operating expenses paid or incurred for production or collection of gross income or for management, conservation, or maintenance of property held for production of income (see instructions)	6
7	Other expenses (see instructions)	7
8	Adjusted Net Income (subtract lines 5, 6 and 7 from line 4)	8

	Section B - Minimum Asset Amount		(A) Prior Year	(B) Current Year (optional)
1	Aggregate fair market value of all non-exempt-use assets (see instructions for short tax year or assets held for part of year):	1
a	Average monthly value of securities	1a
b	Average monthly cash balances	1b
c	Fair market value of other non-exempt-use assets	1c
d	Total (add lines 1a, 1b, and 1c)	1d
e	Discount claimed for blockage or other factors (explain in detail in Part VI):
2	Acquisition indebtedness applicable to non-exempt use assets	2
3	Subtract line 2 from line 1d	3
4	Cash deemed held for exempt use. Enter 0.015 of line 3 (for greater amount, see instructions).	4
5	Net value of non-exempt-use assets (subtract line 4 from line 3)	5
6	Multiply line 5 by 0.035	6
7	Recoveries of prior-year distributions	7
8	Minimum Asset Amount (add line 7 to line 6)	8

	Section C - Distributable Amount		Current Year
1	Adjusted net income for prior year (from Section A, line 8, Column A)	1
2	Enter 85% of line 1	2
3	Minimum asset amount for prior year (from Section B, line 8, Column A)	3
4	Enter greater of line 2 or line 3	4
5	Income tax imposed in prior year	5
6	Distributable Amount. Subtract line 5 from line 4, unless subject to emergency temporary reduction (see instructions)	6

Check here if the current year is the organization's first as a non-functionally-integrated Type III supporting organization (see instructions)

Schedule A (Form 990) 2024

Page 7

Part V

Type III Non-Functionally Integrated 509(a)(3) Supporting Organizations(continued)

Section D - Distributions		Current Year
1 Amounts paid to supported organizations to accomplish exempt purposes	1
2 Amounts paid to perform activity that directly furthers exempt purposes of supported organizations, in excess of income from activity	2
3 Administrative expenses paid to accomplish exempt purposes of supported organizations	3
4 Amounts paid to acquire exempt-use assets	4
5 Qualified set-aside amounts (prior IRS approval required - provide details in Part VI)	5
6 Other distributions (describe in Part VI). See instructions	6
7Total annual distributions. Add lines 1 through 6.	7
8 Distributions to attentive supported organizations to which the organization is responsive (provide details in Part VI). See instructions	8
9 Distributable amount for 2024 from Section C, line 6	9
10 Line 8 amount divided by Line 9 amount	10

Section E - Distribution Allocations (see instructions)		(i) Excess Distributions	(ii) Underdistributions Pre-2024	(iii) Distributable Amount for 2024
1 Distributable amount for 2024 from Section C, line 6
2 Underdistributions, if any, for years prior to 2024 (reasonable cause required-- explain in Part VI). See instructions.
3 Excess distributions carryover, if any, to 2024:
a From 2019.......
b From 2020.......
c From 2021.......
d From 2022.......
e From 2023.......
fTotal of lines 3a through e
g Applied to underdistributions of prior years
h Applied to 2024 distributable amount
i Carryover from 2019 not applied (see instructions)
j Remainder. Subtract lines 3g, 3h, and 3i from line 3f.
4Distributions for 2024 from Section D, line 7:
$
a Applied to underdistributions of prior years
b Applied to 2024 distributable amount
c Remainder. Subtract lines 4a and 4b from line 4.
5 Remaining underdistributions for years prior to 2024, if any. Subtract lines 3g and 4a from line 2. If the amount is greater than zero, explain in Part VI. See instructions.
6 Remaining underdistributions for 2024. Subtract lines 3h and 4b from line 1. If the amount is greater than zero, explain in Part VI. See instructions.
7 Excess distributions carryover to 2025. Add lines 3j and 4c.
8 Breakdown of line 7:
a Excess from 2020.....
b Excess from 2021.....
c Excess from 2022.....
d Excess from 2023.....
e Excess from 2024.....

Schedule A (Form 990) (2024)

Schedule A (Form 990) 2024

Page 8

Part VI

Supplemental Information. Provide the explanations required by Part II, line 10; Part II, line 17a or 17b; Part III, line 12; Part IV, Section A, lines 1, 2, 3b, 3c, 4b, 4c, 5a, 6, 9a, 9b, 9c, 11a, 11b, and 11c; Part IV, Section B, lines 1 and 2; Part IV, Section C, line 1; Part IV, Section D, lines 2 and 3; Part IV, Section E, lines 1c, 2a, 2b, 3a and 3b; Part V, line 1; Part V, Section B, line 1e; Part V Section D, lines 5, 6, and 8; and Part V, Section E, lines 2, 5, and 6. Also complete this part for any additional information. (See instructions).

Facts And Circumstances Test

Return Reference	Explanation

Schedule A (Form 990) 2024

Additional Data

Software ID:
Software Version:

- TIN:

Schedule B
(Form 990)
(Rev. January 2025)

Department of the Treasury
Internal Revenue Service

Schedule of Contributors

Attach to Form 990, 990-EZ, or 990-PF.

Go to www.irs.gov/Form990 for the latest information.

OMB No. 1545-0047

Name of the organization

HENNEPIN HEALTHCARE RESEARCH INSTITUTE

Employer identification number

41-1677920

Organization type (check one):

Filers of:

Section:

Form 990 or 990-EZ

501(c)( ) (enter number) organization

4947(a)(1) nonexempt charitable trust not treated as a private foundation

527 political organization

Form 990-PF

501(c)(3) exempt private foundation

4947(a)(1) nonexempt charitable trust treated as a private foundation

501(c)(3) taxable private foundation

Check if your organization is covered by the General Rule or a Special Rule.
Note: Only a section 501(c)(7), (8), or (10) organization can check boxes for both the General Rule and a Special Rule. See instructions.

General Rule

For an organization filing Form 990, 990-EZ, or 990-PF that received, during the year, contributions totaling $5,000 or more (in money or other property) from any one contributor. Complete Parts I and II. See instructions for determining a contributor's total contributions.

Special Rules

For an organization described in section 501(c)(3) filing Form 990 or 990-EZ that met the 33¹/3% support test of the regulations
under sections 509(a)(1) and 170(b)(1)(A)(vi), that checked Schedule A (Form 990 or 990-EZ), Part II, line 13, 16a, or 16b, and that received from any one contributor, during the year, total contributions of the greater of (1) $5,000 or (2) 2% of the amount on (i) Form 990, Part VIII, line 1h, or (ii) Form 990-EZ, line 1. Complete Parts I and II.

For an organization described in section 501(c)(7), (8), or (10) filing Form 990 or 990-EZ that received from any one contributor,
during the year, total contributions of more than $1,000 exclusively for religious, charitable, scientific, literary, or educational purposes, or for the prevention of cruelty to children or animals. Complete Parts I, II, and III.

For an organization described in section 501(c)(7), (8), or (10) filing Form 990 or 990-EZ that received from any one contributor,
during the year, contributions exclusively for religious, charitable, etc., purposes, but no such contributions totaled more than $1,000. If this box is checked, enter here the total contributions that were received during the year for an exclusively religious, charitable, etc., purpose. Don't complete any of the parts unless the General Rule applies to this organization because it received nonexclusively religious, charitable, etc., contributions totaling $5,000 or more during the year ......... Right Arrow

Caution: An organization that isn't covered by the General Rule and/or the Special Rules doesn't file Schedule B (Form 990,
990-EZ, or 990-PF), but it must answer “No” on Part IV, line 2, of its Form 990; or check the box on line H of its Form 990-EZ
or on its Form 990PF, Part I, line 2, to certify that it doesn't meet the filing requirements of Schedule B (Form 990,
990-EZ, or 990-PF).

For Paperwork Reduction Act Notice, see the Instructions
for Form 990, 990-EZ, or 990-PF.

Cat. No. 30613XSchedule B (Form 990) (Rev. 1-2025)

Schedule B (Form 990) (Rev. 1-2025) Page 2

Name of organization HENNEPIN HEALTHCARE RESEARCH INSTITUTE

Part I	Contributors (see instructions). Use duplicate copies of Part I if additional space is needed.
(a) No.	(b) Name, address, and ZIP + 4	(c) Total contributions	(d) Type of contribution
RESTRICTED	,	$ RESTRICTED	Person Payroll Noncash (Complete Part II for noncash contributions.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Total contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II for noncash contributions.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Total contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II for noncash contributions.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Total contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II for noncash contributions.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Total contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II for noncash contributions.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Total contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II for noncash contributions.)
Schedule B (Form 990) (Rev. 1-2025)

Schedule B (Form 990) (Rev. 1-2025)

Page 3

Name of organization HENNEPIN HEALTHCARE RESEARCH INSTITUTE		Employer identification number 41-1677920

Part II	Noncash Property (see instructions). Use duplicate copies of Part II if additional space is needed.
(a) No. from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (See instructions)	(d) Date received
		$
(a) No. from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (See instructions)	(d) Date received
		$
(a) No. from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (See instructions)	(d) Date received
		$
(a) No. from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (See instructions)	(d) Date received
		$
(a) No. from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (See instructions)	(d) Date received
		$
(a) No. from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (See instructions)	(d) Date received
		$
Schedule B (Form 990) (Rev. 1-2025)

Schedule B (Form 990) (Rev. 1-2025)

Page 4


Name of organization HENNEPIN HEALTHCARE RESEARCH INSTITUTE			Employer identification number 41-1677920
Part III Exclusively religious, charitable, etc., contributions to organizations described in section 501(c) (7), (8), or (10) that total more than $1,000 for the year from any one contributor. Complete columns (a) through (e) and the following line entry. For organizations completing Part III, enter the total of exclusively religious, charitable, etc., contributions of $1,000 or less for the year. (Enter this information once. See instructions.) $ Use duplicate copies of Part III if additional space is needed.

(a)
No. from Part I

(b) Purpose of gift

(d) Description of how gift is held

(e) Transfer of gift
Transferee's name, address, and ZIP 4	Relationship of transferor to transferee

(a)
No. from Part I

(b) Purpose of gift

(d) Description of how gift is held

(e) Transfer of gift
Transferee's name, address, and ZIP 4	Relationship of transferor to transferee

(a)
No. from Part I

(b) Purpose of gift

(d) Description of how gift is held

(e) Transfer of gift
Transferee's name, address, and ZIP 4	Relationship of transferor to transferee

(a)
No. from Part I

(b) Purpose of gift

(d) Description of how gift is held

(e) Transfer of gift
Transferee's name, address, and ZIP 4	Relationship of transferor to transferee

Schedule B (Form 990) (Rev. 1-2025)

Additional Data

Software ID:
Software Version:

- TIN:

SCHEDULE C
(Form 990)

Department of the Treasury
Internal Revenue Service

Political Campaign and Lobbying Activities

For Organizations Exempt From Income Tax Under section 501(c) and section 527

right arrow

Complete if the organization is described below. right arrow

Attach to Form 990 or Form 990-EZ.
right arrow

Go to www.irs.gov/Form990 for instructions and the latest information.

OMB No. 1545-0047

2024

Open to Public
Inspection

If the organization answered "Yes" on Form 990, Part IV, Line 3, or Form 990-EZ, Part V, line 46 (Political Campaign Activities), then
Round Bullet

Section 501(c)(3) organizations: Complete Parts I-A and B. Do not complete Part I-C.
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Section 501(c) (other than section 501(c)(3)) organizations: Complete Parts I-A and C below. Do not complete Part I-B.
Round Bullet

Section 527 organizations: Complete Part I-A only.
If the organization answered "Yes" on Form 990, Part IV, Line 4, or Form 990-EZ, Part VI, line 47 (Lobbying Activities), then
Round Bullet

Section 501(c)(3) organizations that have filed Form 5768 (election under section 501(h)): Complete Part II-A. Do not complete Part II-B.
Round Bullet

Section 501(c)(3) organizations that have NOT filed Form 5768 (election under section 501(h)): Complete Part II-B. Do not complete Part II-A.
If the organization answered "Yes" on Form 990, Part IV, Line 5 (Proxy Tax) (see separate instructions) or Form 990-EZ, Part V, line 35c (Proxy Tax) (see separate instructions), then
Round Bullet

Section 501(c)(4), (5), or (6) organizations: Complete Part III.

Name of the organization

HENNEPIN HEALTHCARE RESEARCH INSTITUTE

Employer identification number

41-1677920

Part I-A

Complete if the organization is exempt under section 501(c) or is a section 527 organization.

Provide a description of the organization’s direct and indirect political campaign activities in Part IV. See instructions for definition of “political campaign activities."

Political campaign activity expenditures. See instructions .................................................................... right arrow

Volunteer hours for political campaign activities. See instructions ..................................................................

Part I-B

Complete if the organization is exempt under section 501(c)(3).

Enter the amount of any excise tax incurred by the organization under section 4955 ................................ right arrow

Enter the amount of any excise tax incurred by organization managers under section 4955 ....................... right arrow

If the organization incurred a section 4955 tax, did it file Form 4720 for this year? .........................................

Yes No

Was a correction made? ......................................................................................................................

Yes No

If "Yes," describe in Part IV.

Part I-C

Complete if the organization is exempt under section 501(c), except section 501(c)(3).

Enter the amount directly expended by the filing organization for section 527 exempt function activities ..... right arrow

Enter the amount of the filing organization's funds contributed to other organizations for section 527 exempt function activities ............................................................................................................................ right arrow

Total exempt function expenditures. Add lines 1 and 2. Enter here and on Form 1120-POL, line 17b........... right arrow

Did the filing organization file Form 1120-POL for this year? ...................................................................

Yes No

Enter the names, addresses and employer identification number (EIN) of all section 527 political organizations to which the filing
organization made payments. For each organization listed, enter the amount paid from the filing organization’s funds. Also enter the amount of political contributions received that were promptly and directly delivered to a separate political organization, such as a separate segregated fund or a political action committee (PAC). If additional space is needed, provide information in Part IV.

(a) Name	(b) Address	(c) EIN	(d) Amount paid from filing organization's funds. If none, enter -0-.	(e) Amount of political contributions received and promptly and directly delivered to a separate political organization. If none, enter -0-.
1
2
3
4
5
6

For Paperwork Reduction Act Notice, see the instructions for Form 990.

Cat. No. 50084S

Schedule C (Form 990) 2024

Page 2

Part II-A

Complete if the organization is exempt under section 501(c)(3) and filed Form 5768 (election under section 501(h)).

A Check right arrow

if the filing organization belongs to an affiliated group (and list in Part IV each affiliated group member's name, address, EIN, expenses, and share of excess lobbying expenditures).
B Check right arrow

if the filing organization checked box A and "limited control" provisions apply.

Limits on Lobbying Expenditures (The term "expenditures" means amounts paid or incurred.)		(b) Affiliated group totals
1a	Total lobbying expenditures to influence public opinion (grass roots lobbying) ......................
b	Total lobbying expenditures to influence a legislative body (direct lobbying) ........................
c	Total lobbying expenditures (add lines 1a and 1b) ............................................................
d	Other exempt purpose expenditures ...............................................................................
e	Total exempt purpose expenditures (add lines 1c and 1d) ..................................................
f	Lobbying nontaxable amount. Enter the amount from the following table in both columns.
	If the amount on line 1e, column (a) or (b) is:The lobbying nontaxable amount is:
	Not over $500,00020% of the amount on line 1e.
	Over $500,000 but not over $1,000,000$100,000 plus 15% of the excess over $500,000.
	Over $1,000,000 but not over $1,500,000$175,000 plus 10% of the excess over $1,000,000.
	Over $1,500,000 but not over $17,000,000$225,000 plus 5% of the excess over $1,500,000.
	Over $17,000,000$1,000,000.

g	Grassroots nontaxable amount (enter 25% of line 1f) .................................................
h	Subtract line 1g from line 1a. If zero or less, enter -0-. ................................................
i	Subtract line 1f from line 1c. If zero or less, enter -0-. ................................................
j	If there is an amount other than zero on either line 1h or line 1i, did the organization file Form 4720 reporting section 4911 tax for this year? ...................................................................................................................	Yes No

4-Year Averaging Period Under Section 501(h) (Some organizations that made a section 501(h) election do not have to complete all of the five columns below. See the separate instructions for lines 2a through 2f.)
Lobbying Expenditures During 4-Year Averaging Period
	Calendar year (or fiscal year beginning in)	(a) 2021	(b) 2022	(c) 2023	(d) 2024	(e) Total

2a	Lobbying nontaxable amount

b	Lobbying ceiling amount (150% of line 2a, column(e))

c	Total lobbying expenditures

d	Grassroots nontaxable amount

e	Grassroots ceiling amount (150% of line 2d, column (e))

f	Grassroots lobbying expenditures

Schedule C (Form 990) 2024

Page 3

Part II-B

Complete if the organization is exempt under section 501(c)(3) and has NOT filed Form 5768 (election under section 501(h)).

For each "Yes" response on lines 1a through 1i below, provide in Part IV a detailed description of the lobbying activity.

(a)

Yes

(b)

Amount

During the year, did the filing organization attempt to influence foreign, national, state or local legislation, including any attempt to influence public opinion on a legislative matter or referendum, through the use of:

Volunteers? ...........................................................................................................

Paid staff or management (include compensation in expenses reported on lines 1c through 1i)? ........

Media advertisements? ...................................................................................................

Mailings to members, legislators, or the public? .............................................................................

Publications, or published or broadcast statements? ...........................................................

Grants to other organizations for lobbying purposes? ..........................................................

Yes

1,000

Direct contact with legislators, their staffs, government officials, or a legislative body? .......................

Rallies, demonstrations, seminars, conventions, speeches, lectures, or any similar means? ..................

Other activities? ...................................................................................................................

Total. Add lines 1c through 1i ....................................................................................................

1,000

Did the activities in line 1 cause the organization to be not described in section 501(c)(3)? .....

If "Yes," enter the amount of any tax incurred under section 4912 ...........................................

If "Yes," enter the amount of any tax incurred by organization managers under section 4912 ...................

If the filing organization incurred a section 4912 tax, did it file Form 4720 for this year? ........................

Part III-A

Complete if the organization is exempt under section 501(c)(4), section 501(c)(5), or section 501(c)(6).

Yes

Were substantially all (90% or more) dues received nondeductible by members? ...............................................

Did the organization make only in-house lobbying expenditures of $2,000 or less? ............................................

Did the organization agree to carry over lobbying and political expenditures from the prior year? .................................

Part III-B

Complete if the organization is exempt under section 501(c)(4), section 501(c)(5), or section 501(c)(6) and if either (a) BOTH Part III-A, lines 1 and 2, are answered "No" OR (b) Part III-A, line 3, is answered “Yes."

Dues, assessments and similar amounts from members ......................................................................

Section 162(e) nondeductible lobbying and political expenditures (do not include amounts of political expenses for which the section 527(f) tax was paid).

Current year .............................................................................................................................

Carryover from last year ............................................................................................................

Total ...........................................................................................................................................

Aggregate amount reported in section 6033(e)(1)(A) notices of nondeductible section 162(e) dues .

If notices were sent and the amount on line 2c exceeds the amount on line 3, what portion of the excess does the organization agree to carryover to the reasonable estimate of nondeductible lobbying and political expenditure next year? ......................................................................................................................

Taxable amount of lobbying and political expenditures. See Instructions .........................................

Part IV

Supplemental Information

Provide the descriptions required for Part l-A, line 1; Part l-B, line 4; Part l-C, line 5; Part II-A (affiliated group list); Part II-A, lines 1 and 2 (see instructions), and Part ll-B, line 1. Also, complete this part for any additional information.

Return Reference	Explanation
PART II-B, LINE 1:	THE HENNEPIN HEALTHCARE RESEARCH INSTITUTE (HHRI) PAID $2,500 IN 2024 TO THE NATIONAL ASSOCIATION FOR BIOMEDICAL RESEARCH (NABR) FOR MEMBERSHIP DUES. THE NABR ESTIMATES 40% OF THE MEMBERSHIP DUES PAYMENT IS ATTRIBUTABLE TO NONDEDUCTIBLE LOBBYING EXPENSE. THE NABR IS A NATIONAL, NON-PARTISAN, NON-PROFIT ORGANIZATION DEDICATED TO SOUND PUBLIC POLICY THAT RECOGNIZES THE VITAL ROLE OF HUMANE ANIMAL USE IN BIOMEDICAL RESEARCH, HIGHER EDUCATION AND PRODUCT SAFETY TESTING. THE NABR PROVIDES THE UNIFIED VOICE FOR THE SCIENTIFIC COMMUNITY ON LEGISLATIVE AND REGULATORY MATTERS AFFECTING LABORATORY ANIMAL RESEARCH.

Return Reference

Explanation

PART II-B, LINE 1:

THE HENNEPIN HEALTHCARE RESEARCH INSTITUTE (HHRI) PAID $2,500 IN 2024 TO THE NATIONAL ASSOCIATION FOR BIOMEDICAL RESEARCH (NABR) FOR MEMBERSHIP DUES. THE NABR ESTIMATES 40% OF THE MEMBERSHIP DUES PAYMENT IS ATTRIBUTABLE TO NONDEDUCTIBLE LOBBYING EXPENSE. THE NABR IS A NATIONAL, NON-PARTISAN, NON-PROFIT ORGANIZATION DEDICATED TO SOUND PUBLIC POLICY THAT RECOGNIZES THE VITAL ROLE OF HUMANE ANIMAL USE IN BIOMEDICAL RESEARCH, HIGHER EDUCATION AND PRODUCT SAFETY TESTING. THE NABR PROVIDES THE UNIFIED VOICE FOR THE SCIENTIFIC COMMUNITY ON LEGISLATIVE AND REGULATORY MATTERS AFFECTING LABORATORY ANIMAL RESEARCH.

Schedule C (Form 990) 2024

Additional Data

Software ID:
Software Version:

- TIN:

SCHEDULE D
(Form 990)

Department of the Treasury
Internal Revenue Service

Supplemental Financial Statements

Complete if the organization answered "Yes," on Form 990,
Part IV, line 6, 7, 8, 9, 10, 11a, 11b, 11c, 11d, 11e, 11f, 12a, or 12b.
right arrow

Attach to Form 990.
right arrow

Go to www.irs.gov/Form990 for instructions and the latest information.

OMB No. 1545-0047

Open to Public Inspection

Name of the organization

HENNEPIN HEALTHCARE RESEARCH INSTITUTE

Employer identification number

41-1677920

Part I

Organizations Maintaining Donor Advised Funds or Other Similar Funds or Accounts. Complete if the organization answered "Yes" on Form 990, Part IV, line 6.

		(a) Donor advised funds	(b) Funds and other accounts
1	Total number at end of year .........
2	Aggregate value of contributions to (during year)
3	Aggregate value of grants from (during year)
4	Aggregate value at end of year ........

Did the organization inform all donors and donor advisors in writing that the assets held in donor advised funds are the organization’s property, subject to the organization’s exclusive legal control? ............

Yes No

Did the organization inform all grantees, donors, and donor advisors in writing that grant funds can be used only for charitable purposes and not for the benefit of the donor or donor advisor, or for any other purpose conferring impermissible private benefit? ...................................

Yes No

Part II

Conservation Easements.
Complete if the organization answered "Yes" on Form 990, Part IV, line 7.

Purpose(s) of conservation easements held by the organization (check all that apply).

Preservation of land for public use (e.g., recreation or education) Preservation of an historically important land area

Protection of natural habitat Preservation of a certified historic structure

Preservation of open space

Complete lines 2a through 2d if the organization held a qualified conservation contribution in the form of a conservation easement on the last day of the tax year.


a	Total number of conservation easements ......................	2a
b	Total acreage restricted by conservation easements ....................	2b
c	Number of conservation easements on a certified historic structure included in (a) .....	2c
d	Number of conservation easements included in (c) acquired after July 25, 2006, and not on a historic structure listed in the National Register ...	2d

Number of conservation easements modified, transferred, released, extinguished, or terminated by the organization during the
tax year right arrow

Number of states where property subject to conservation easement is located right arrow

Does the organization have a written policy regarding the periodic monitoring, inspection, handling of violations, and enforcement of the conservation easements it holds? ............

Yes No

Staff and volunteer hours devoted to monitoring, inspecting, handling of violations, and enforcing conservation easements during the year
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Amount of expenses incurred in monitoring, inspecting, handling of violations, and enforcing conservation easements during the year
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Does each conservation easement reported on line 2(d) above satisfy the requirements of section 170(h)(4)(B)(i) and section 170(h)(4)(B)(ii)? .............................

Yes No

In Part XIII, describe how the organization reports conservation easements in its revenue and expense statement, and
balance sheet, and include, if applicable, the text of the footnote to the organization’s financial statements that describes
the organization’s accounting for conservation easements.

Part III

Organizations Maintaining Collections of Art, Historical Treasures, or Other Similar Assets.
Complete if the organization answered "Yes" on Form 990, Part IV, line 8.

If the organization elected, as permitted under FASB ASC 958, not to report in its revenue statement and balance sheet works of art, historical treasures, or other similar assets held for public exhibition, education, or research in furtherance of public service, provide, in Part XIII, the text of the footnote to its financial statements that describes these items.

If the organization elected, as permitted under FASB ASC 958, to report in its revenue statement and balance sheet works of art, historical treasures, or other similar assets held for public exhibition, education, or research in furtherance of public service, provide the following amounts relating to these items:

(i)

Revenue included on Form 990, Part VIII, line 1 ......................... right arrow

(ii)

Assets included in Form 990, Part X ............................... right arrow

If the organization received or held works of art, historical treasures, or other similar assets for financial gain, provide the
following amounts required to be reported under FASB ASC 958 relating to these items:

Revenue included on Form 990, Part VIII, line 1 .......................... right arrow

Assets included in Form 990, Part X ............................... right arrow

For Paperwork Reduction Act Notice, see the Instructions for Form 990.

Cat. No. 52283D

Schedule D (Form 990) (Rev. 1-2025)

Page 2

Part III

Organizations Maintaining Collections of Art, Historical Treasures, or Other Similar Assets (continued)

Using the organization’s acquisition, accession, and other records, check any of the following that are a significant use of its collection items (check all that apply):

Public exhibition

Loan or exchange programs

Scholarly research

Other

Preservation for future generations

Provide a description of the organization’s collections and explain how they further the organization’s exempt purpose in
Part XIII.

During the year, did the organization solicit or receive donations of art, historical treasures or other similar
assets to be sold to raise funds rather than to be maintained as part of the organization’s collection?...

Yes No

Part IV

Escrow and Custodial Arrangements. Complete if the organization answered "Yes" on Form 990, Part IV, line 9, or reported an amount on Form 990, Part X, line 21.

Is the organization an agent, trustee, custodian or other intermediary for contributions or other assets not
included on Form 990, Part X? ....................................

Yes No


b	If "Yes," explain the arrangement in Part XIII and complete the following table:		Amount
c	Beginning balance .............................	1c
d	Additions during the year ............................	1d
e	Distributions during the year ..........................	1e
f	Ending balance ................................	1f

Did the organization include an amount on Form 990, Part X, line 21, for escrow or custodial account liability? ...

Yes No

If "Yes," explain the arrangement in Part XIII. Check here if the explanation has been provided in Part XIII ....

Part V

Endowment Funds.
Complete if the organization answered "Yes" on Form 990, Part IV, line 10.

		(a) Current year	(b) Prior year	(c) Two years back	(d) Three years back	(e) Four years back

1a	Beginning of year balance ....	19,200,509	17,197,502	21,292,807	19,327,501	19,489,098
b	Contributions ...
c	Net investment earnings, gains, and losses	2,313,891	2,950,699	-3,322,590	2,726,548	2,476,526
d	Grants or scholarships ...
e	Other expenditures for facilities and programs ...	739,980	725,243	543,342	507,922	429,686
f	Administrative expenses ....	343,732	222,449	229,373	253,320	208,437
g	End of year balance ......	20,430,688	19,200,509	17,197,502	21,292,807	19,327,501

Provide the estimated percentage of the current year end balance (line 1g, column (a)) held as:

Board designated or quasi-endowment right arrow

0 %

Permanent endowment right arrow

100.000 %

Term endowment right arrow

0 %

The percentages on lines 2a, 2b, and 2c should equal 100%.

Are there endowment funds not in the possession of the organization that are held and administered for the
organization by:

Yes

(i) Unrelated organizations .................

3a(i)

Yes

(ii) Related organizations .................

3a(ii)

If "Yes" on 3a(ii), are the related organizations listed as required on Schedule R? .........

Describe in Part XIII the intended uses of the organization's endowment funds.

Part VI

Land, Buildings, and Equipment.
Complete if the organization answered "Yes" on Form 990, Part IV, line 11a. See Form 990, Part X, line 10.

Description of property		(a) Cost or other basis (investment)	(b) Cost or other basis (other)	(c) Accumulated depreciation	(d) Book value

1a	Land .....
b	Buildings ....
c	Leasehold improvements	7,134,980	6,847,476	287,504
d	Equipment ....	6,143,552	4,975,746	1,167,806
e	Other .....
Total. Add lines 1a through 1e. (Column (d) must equal Form 990, Part X, column (B), line 10(c).)..				1,455,310

Schedule D (Form 990) (Rev. 1-2025)

Page 3

Part VII

Investments - Other Securities.
Complete if the organization answered "Yes" on Form 990, Part IV, line 11b. See Form 990, Part X, line 12.

(a) Description of security or category (including name of security)	(b) Book value	(c) Method of valuation: Cost or end-of-year market value
(1) Financial derivatives.........
(2) Closely-held equity interests........
(3)Other
(A)
(B)
(C)
(D)
(E)
(F)
(G)
(H)
Total. (Column (b) must equal Form 990, Part X, col. (B) line 12.)

Part VIII

Investments - Program Related. Complete if the organization answered 'Yes' on Form 990, Part IV, line 11c. See Form 990, Part X, line 13.

(a) Description of investment	(b) Book value	(c) Method of valuation: Cost or end-of-year market value

(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
Total. (Column (b) must equal Form 990, Part X, col.(B) line 13.)

Part IX

Other Assets.
Complete if the organization answered 'Yes' on Form 990, Part IV, line 11d. See Form 990, Part X, line 15.

(a) Description				(b) Book value

(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
Total. (Column (b) must equal Form 990, Part X, col.(B) line 15.)...........

Part X

Other Liabilities.
Complete if the organization answered 'Yes' on Form 990, Part IV, line 11e or 11f. See Form 990, Part X, line 25.

1.(a) Description of liability	(b) Book value
(1) Federal income taxes
DUE TO RELATED ENTITIES	1,333,973
SUBSCRIPTION LIABILITIES	572,430







Total. (Column (b) must equal Form 990, Part X, col.(B) line 25.)	1,906,403
2. Liability for uncertain tax positions. In Part XIII, provide the text of the footnote to the organization's financial statements that reports the organization's liability for uncertain tax positions under FIN 48 (ASC 740). Check here if the text of the footnote has been provided in Part XIII

Schedule D (Form 990) (Rev. 1-2025)

Page 4

Part XI Reconciliation of Revenue per Audited Financial Statements With Revenue per Return. Complete if the organization answered 'Yes' on Form 990, Part IV, line 12a.
1	Total revenue, gains, and other support per audited financial statements .......			1	57,997,108
2	Amounts included on line 1 but not on Form 990, Part VIII, line 12:
a	Net unrealized gains (losses) on investments ....	2a	3,569,334
b	Donated services and use of facilities .........	2b
c	Recoveries of prior year grants ...........	2c
d	Other (Describe in Part XIII.) ...........	2d	7,805
e	Add lines 2a through 2d .....................			2e	3,577,139
3	Subtract line 2e from line 1..................			3	54,419,969
4	Amounts included on Form 990, Part VIII, line 12, but not on line 1:
a	Investment expenses not included on Form 990, Part VIII, line 7b .	4a
b	Other (Describe in Part XIII.) ...........	4b	297,252
c	Add lines 4a and 4b....................			4c	297,252
5	Total revenue. Add lines 3 and 4c. (This must equal Form 990, Part I, line 12.) ......			5	54,717,221

Part XII Reconciliation of Expenses per Audited Financial Statements With Expenses per Return. Complete if the organization answered 'Yes' on Form 990, Part IV, line 12a.
1	Total expenses and losses per audited financial statements ...........			1	53,512,208
2	Amounts included on line 1 but not on Form 990, Part IX, line 25:
a	Donated services and use of facilities .........	2a
b	Prior year adjustments ............	2b
c	Other losses ................	2c
d	Other (Describe in Part XIII.) ...........	2d	7,805
e	Add lines 2a through 2d....................			2e	7,805
3	Subtract line 2e from line 1...................			3	53,504,403
4	Amounts included on Form 990, Part IX, line 25, but not on line 1:
a	Investment expenses not included on Form 990, Part VIII, line 7b ..	4a
b	Other (Describe in Part XIII.) ...........	4b
c	Add lines 4a and 4b.....................			4c	0
5	Total expenses. Add lines 3 and 4c. (This must equal Form 990, Part I, line 18.) ......			5	53,504,403

Part XIII

Supplemental Information

Provide the descriptions required for Part II, lines 3, 5, and 9; Part III, lines 1a and 4; Part lV, lines 1b and 2b; Part V, line 4; Part X, line 2; Part XI, lines 2d and 4b; and Part XII, lines 2d and 4b. Also complete this part to provide any additional information.

Return Reference	Explanation
PART V, LINE 4:	ALL HENNEPIN HEALTHCARE RESEARCH INSTITUTE (HHRI) ENDOWMENTS ARE PERMANENTLY RESTRICTED AND ARE USED IN ACCORDANCE WITH DONOR INTENT.
PART X, LINE 2:	HHRI IS EXEMPT FROM INCOME TAXES AS A NONPROFIT CORPORATION UNDER IRC SECTION 501(C)(3) AND IS AN ORGANIZATION THAT IS NOT A PRIVATE FOUNDATION UNDER IRC. HHRI IS ANNUALLY REQUIRED TO FILE A RETURN OF ORGANIZATION EXEMPT FROM INCOME TAX (FORM 990) WITH THE IRS. IN ADDITION, HHRI IS SUBJECT TO INCOME TAX ON NET INCOME THAT IS DERIVED FROM BUSINESS ACTIVITIES THAT ARE UNRELATED TO ITS EXEMPT PURPOSE. HHRIS HAS DETERMINED IN 2024 THAT IT IS NOT SUBJECT TO UNRELATED BUSINESS INCOME TAX. HHRI BELIEVES THAT IT HAS APPROPRIATE SUPPORT FOR ANY TAX POSITIONS TAKEN AFFECTING ITS ANNUAL FILING REQUIREMENTS, AND AS SUCH, DOES NOT HAVE ANY UNCERTAIN TAX POSITIONS THAT ARE MATERIAL TO THE FINANCIAL STATEMENTS. HHRI WOULD RECOGNIZE FUTURE ACCRUED INTEREST AND PENALTIES RELATED TO UNRECOGNIZED TAX BENEFITS AND LIABILITIES IN INCOME TAX EXPENSE IF SUCH INTEREST AND PENALTIES ARE INCURRED. HHRI'S 2021-2024 TAX YEARS ARE OPEN FOR EXAMINATION BY FEDERAL AND STATE TAXING AUTHORITIES. HHRI FILES AS A TAX-EXEMPT ORGANIZATION. SHOULD THAT STATUS BE CHALLENGED IN THE FUTURE, ALL YEARS SINCE INCEPTION WOULD BE SUBJECT TO REVIEW BY THE IRS.
PART XI, LINE 2D - OTHER ADJUSTMENTS:	ASSET DISPOSAL 7,805.
PART XI, LINE 4B - OTHER ADJUSTMENTS:	EQUITY TRANSFER 297,252.
PART XII, LINE 2D - OTHER ADJUSTMENTS:	ASSET DISPOSAL 7,805.

Schedule D (Form 990) (Rev. 1-2025)

Additional Data

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Software Version:

- TIN:

SCHEDULE F(Form 990)
(Rev. January 2025)

Department of the Treasury
Internal Revenue Service

Statement of Activities Outside the United States

Complete if the organization answered "Yes" to Form 990, Part IV, line 14b, 15, or 16. Right arrow

Attach to Form 990. Right arrow

Go to www.irs.gov/Form990 for instructions and the latest information.

OMB No. 1545-0047

Open to Public Inspection

Name of the organization
HENNEPIN HEALTHCARE RESEARCH INSTITUTE

Employer identification number

41-1677920

Part I

General Information on Activities Outside the United States. Complete if the organization answered "Yes" on Form 990, Part IV, line 14b.

For grantmakers. Does the organization maintain records to substantiate the amount of its grants and

other assistance, the grantees’ eligibility for the grants or assistance, and the selection criteria used

to award the grants or assistance? . . . . . . . . . . . . . . . . . . . . . . . . .

Yes

For grantmakers. Describe in Part V the organization’s procedures for monitoring the use of its grants and other assistance outside the United States.

Activites per Region. (The following Part I, line 3 table can be duplicated if additional space is needed.)

(a) Region		(b) Number of offices in the region	(c) Number of employees, agents, and independent contractors in the region	(d) Activities conducted in region (by type) (such as, fundraising, program services, investments, grants to recipients located in the region)	(e) If activity listed in (d) is a program service, describe specific type of service(s) in the region	(f) Total expenditures for and investments in the region
	EAST ASIA AND THE PACIFIC	0	0	PROGRAM SERVICES	SCIENTIFIC COLLABORATION WITH FOREIGN ENTITY.	3,532,082
	EUROPE (INCLUDING ICELAND & GREENLAND)	0	0	PROGRAM SERVICES	SCIENTIFIC COLLABORATION WITH FOREIGN ENTITY.	52,015
	NORTH AMERICA	0	0	PROGRAM SERVICES	SCIENTIFIC COLLABORATION WITH FOREIGN ENTITY.	4,641
	SUB-SAHARAN AFRICA	0	0	PROGRAM SERVICES	SCIENTIFIC COLLABORATION WITH FOREIGN ENTITY.	325,231













3a	Sub-total ....	0	0			3,913,969
b	Total from continuation sheets to Part I ...	0	0			0
c	Totals (add lines 3a and 3b)	0	0			3,913,969

For Paperwork Reduction Act Notice, see the Instructions for Form 990.Cat. No. 50082W Schedule F (Form 990) (Rev. 1-2025)

Schedule F (Form 990) (Rev. 1-2025)

Page 2

Part II

Grants and Other Assistance to Organizations or Entities Outside the United States. Complete if the organization answered "Yes" on Form 990, Part IV, line 15, for any recipient who received more than $5,000. Part II can be duplicated if additional space is needed.

1 (a) Name of organization		(b) IRS code section and EIN (if applicable)	(c) Region	(d) Purpose of grant	(e) Amount of cash grant	(f) Manner of cash disbursement	(g) Amount of noncash assistance	(h) Description of noncash assistance	(i) Method of valuation (book, FMV, appraisal, other)

2	Enter total number of recipient organizations listed above that are recognized as charities by the foreign country, recognized as tax-exempt by the IRS, or for which the grantee or counsel has provided a section 501(c)(3) equivalency letter .......
3	Enter total number of other organizations or entities .......................

Schedule F (Form 990) (Rev. 1-2025)

Schedule F (Form 990) (Rev. 1-2025)Page 3

Part III

Grants and Other Assistance to Individuals Outside the United States. Complete if the organization answered "Yes" on Form 990, Part IV, line 16.

Part III can be duplicated if additional space is needed.

(a) Type of grant or assistance		(b) Region	(c) Number of recipients	(d) Amount of cash grant	(e) Manner of cash disbursement	(f) Amount of noncash assistance	(g) Description of noncash assistance	(h) Method of valuation (book, FMV, appraisal, other)

Schedule F (Form 990) (Rev. 1-2025)

Page 4

Part IV

Foreign Forms

Schedule F (Form 990) (Rev. 1-2025)

Page 5

Part V

Supplemental Information
Provide the information required by Part I, line 2 (monitoring of funds); Part I, line 3, column (f) (accounting method; amounts of investments vs. expenditures per region); Part II, line 1 (accounting method); Part III (accounting method); and Part III, column (c) (estimated number of recipients), as applicable. Also complete this part to provide any additional information. See instructions.

ReturnReference	Explanation

Schedule F (Form 990) (Rev. 1-2025)

Additional Data

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Schedule J
(Form 990)
(Rev. January 2025)

Department of the Treasury
Internal Revenue Service

Compensation Information

For certain Officers, Directors, Trustees, Key Employees, and Highest
Compensated Employees
medium right arrow graphic

Complete if the organization answered "Yes" on Form 990, Part IV, line 23.
medium right arrow graphic

Attach to Form 990.
medium right arrow graphic

Go to www.irs.gov/Form990 for instructions and the latest information.

OMB No. 1545-0047

Open to Public Inspection

Name of the organization

HENNEPIN HEALTHCARE RESEARCH INSTITUTE

Employer identification number

41-1677920

Part I

Questions Regarding Compensation

Yes

Check the appropiate box(es) if the organization provided any of the following to or for a person listed on Form
990, Part VII, Section A, line 1a. Complete Part III to provide any relevant information regarding these items.

First-class or charter travel Housing allowance or residence for personal use

Travel for companions Payments for business use of personal residence

Tax idemnification and gross-up payments Health or social club dues or initiation fees

Discretionary spending account Personal services (e.g., maid, chauffeur, chef)

If any of the boxes on Line 1a are checked, did the organization follow a written policy regarding payment or reimbursement or provision of all of the expenses described above? If "No," complete Part III to explain .....

Did the organization require substantiation prior to reimbursing or allowing expenses incurred by all
directors, trustees, officers, including the CEO/Executive Director, regarding the items checked on Line 1a? ....

Indicate which, if any, of the following the filing organization used to establish the compensation of the
organization's CEO/Executive Director. Check all that apply. Do not check any boxes for methods
used by a related organization to establish compensation of the CEO/Executive Director, but explain in Part III.

Compensation committee Written employment contract

Independent compensation consultant Compensation survey or study

Form 990 of other organizations Approval by the board or compensation committee

During the year, did any person listed on Form 990, Part VII, Section A, line 1a, with respect to the filing organization or a related organization:

Receive a severance payment or change-of-control payment? .............

Participate in, or receive payment from, a supplemental nonqualified retirement plan? .........

Participate in, or receive payment from, an equity-based compensation arrangement? .........

If "Yes" to any of lines 4a-c, list the persons and provide the applicable amounts for each item in Part III.

Only 501(c)(3), 501(c)(4), and 501(c)(29) organizations must complete lines 5-9.

For persons listed on Form 990, Part VII, Section A, line 1a, did the organization pay or accrue any
compensation contingent on the revenues of:

The organization? ....................

Any related organization? .......................

If "Yes," on line 5a or 5b, describe in Part III.

For persons listed on Form 990, Part VII, Section A, line 1a, did the organization pay or accrue any
compensation contingent on the net earnings of:

The organization? ..................

Any related organization? ......................

If "Yes," on line 6a or 6b, describe in Part III.

For persons listed on Form 990, Part VII, Section A, line 1a, did the organization provide any nonfixed
payments not described in lines 5 and 6? If "Yes," describe in Part III ............

Were any amounts reported on Form 990, Part VII, paid or accured pursuant to a contract that was
subject to the initial contract exception described in Regulations section 53.4958-4(a)(3)? If "Yes," describe
in Part III ..........................

If "Yes" on line 8, did the organization also follow the rebuttable presumption procedure described in Regulations section 53.4958-6(c)? .........................

For Paperwork Reduction Act Notice, see the Instructions for Form 990.

Cat. No. 50053T

Schedule J (Form 990) (Rev. 1-2025)

Page 2

Part II

Officers, Directors, Trustees, Key Employees, and Highest Compensated Employees. Use duplicate copies if additional space is needed.

For each individual whose compensation must be reported on Schedule J, report compensation from the organization on row (i) and from related organizations, described in the
instructions, on row (ii). Do not list any individuals that are not listed on Form 990, Part VII.
Note. The sum of columns (B)(i)-(iii) for each listed individual must equal the total amount of Form 990, Part VII, Section A, line 1a, applicable column (D) and (E) amounts for that individual.

(A) Name and Title		(B) Breakdown of W-2, 1099-MISC compensation, and/or 1099-NEC			(C) Retirement and other deferred compensation	(D) Nontaxable benefits	(E) Total of columns (B)(i)-(D)	(F) Compensation in column (B) reported as deferred on prior Form 990
(A) Name and Title		(i) Base compensation	(ii) Bonus & incentive compensation	(iii) Other reportable compensation	(C) Retirement and other deferred compensation	(D) Nontaxable benefits	(E) Total of columns (B)(i)-(D)
1ANDREW SCHMIDT MD DIRECTOR/PHYSICIAN (UNTIL 6/24)	(i) (ii)	0 ------------- 604,676	0 ------------- 0	0 ------------- 3,864	0 ------------- 30,360	0 ------------- 21,795	0 ------------- 660,695	0 ------------- 0
2MICHAEL PUSKARICH MD MS DIRECTOR/PHYSICIAN	(i) (ii)	0 ------------- 511,729	0 ------------- 0	0 ------------- 1,746	0 ------------- 30,360	0 ------------- 30,036	0 ------------- 573,871	0 ------------- 0
3MEGHAN WALSH MD MPH FACP DIRECTOR/HHS - CARO	(i) (ii)	0 ------------- 474,111	0 ------------- 0	0 ------------- 1,271	0 ------------- 34,500	0 ------------- 30,036	0 ------------- 539,918	0 ------------- 0
4KIRSTEN L JOHANSEN MD PRESIDENT/INVESTIGATOR	(i) (ii)	0 ------------- 475,376	0 ------------- 0	0 ------------- 3,712	0 ------------- 30,360	0 ------------- 28,380	0 ------------- 537,828	0 ------------- 0
5THERESA PESCH RN HHS VP OF PHILANTHROPHY	(i) (ii)	0 ------------- 362,996	0 ------------- 65,344	0 ------------- 2,874	0 ------------- 34,500	0 ------------- 28,380	0 ------------- 494,094	0 ------------- 0
6ERIC LING MD MBA MA DIRECTOR/HHS - CHIEF OF MEDICAL OFFI	(i) (ii)	0 ------------- 316,077	0 ------------- 0	0 ------------- 69	0 ------------- 32,923	0 ------------- 13,427	0 ------------- 362,496	0 ------------- 0
7JASON BAKER MD FORMER VICE PRESIDENT/INVESTIGATOR	(i) (ii)	0 ------------- 293,890	0 ------------- 0	0 ------------- 276	0 ------------- 26,404	0 ------------- 29,964	0 ------------- 350,534	0 ------------- 0
8ANNE FROSCH MD DIRECTOR/INVESTIGATOR	(i) (ii)	0 ------------- 279,157	0 ------------- 0	0 ------------- 180	0 ------------- 25,305	0 ------------- 28,231	0 ------------- 332,873	0 ------------- 0
9DAVID GILBERTSON PROGRAM CO-DIRECTOR	(i) (ii)	259,436 ------------- 0	0 ------------- 0	792 ------------- 0	30,454 ------------- 0	24,412 ------------- 0	315,094 ------------- 0	0 ------------- 0
10AJAY ISRANI MD MS FORMER PRESIDENT/INVESTIGATOR	(i) (ii)	0 ------------- 264,244	0 ------------- 0	0 ------------- 1,819	0 ------------- 23,720	0 ------------- 21,310	0 ------------- 311,093	0 ------------- 0
11RACHEL NYGAARD DIRECTOR/SURGERY RESEARCH	(i) (ii)	231,723 ------------- 0	0 ------------- 0	180 ------------- 0	27,679 ------------- 0	27,465 ------------- 0	287,047 ------------- 0	0 ------------- 0
12ANNE MURRAY MD MS FORMER SECRETARY/TREASURER/INVESTIGA	(i) (ii)	0 ------------- 216,673	0 ------------- 0	0 ------------- 1,524	0 ------------- 20,014	0 ------------- 21,511	0 ------------- 259,722	0 ------------- 0
13JIANNOUNG LIU DIRECTOR, ANALYSIS	(i) (ii)	212,780 ------------- 0	0 ------------- 0	792 ------------- 0	23,342 ------------- 0	22,800 ------------- 0	259,714 ------------- 0	0 ------------- 0
14JON SNYDER DIRECTOR, TRANSPLANT EPIDEMIOLOGY	(i) (ii)	212,808 ------------- 0	0 ------------- 0	276 ------------- 0	23,847 ------------- 0	20,196 ------------- 0	257,127 ------------- 0	0 ------------- 0
15MARK WILLMERT CPA INACTIVE HHF/HHRI - VP OF FINANCE	(i) (ii)	0 ------------- 209,308	0 ------------- 0	0 ------------- 276	0 ------------- 21,099	0 ------------- 12,067	0 ------------- 242,750	0 ------------- 0
16KIM MILLER VP OF OPERATIONS & COO	(i) (ii)	176,576 ------------- 0	0 ------------- 0	516 ------------- 0	18,690 ------------- 0	20,283 ------------- 0	216,065 ------------- 0	0 ------------- 0
17SHULING LI EPIDDEMIOLOGIST & BIOSTATISTICIAN	(i) (ii)	174,266 ------------- 0	0 ------------- 0	516 ------------- 0	18,201 ------------- 0	19,505 ------------- 0	212,488 ------------- 0	0 ------------- 0

Schedule J (Form 990) (Rev. 1-2025)

Page 3

Part III

Supplemental Information

Provide the information, explanation, or descriptions required for Part I, lines 1a, 1b, 3, 4a, 4b, 4c, 5a, 5b, 6a, 6b, 7, and 8, and for Part II. Also complete this part for any additional information.

Return Reference	Explanation
PART I, LINE 3	THE PRESIDENT WAS PAID BY A RELATED ORGANIZATION, HENNEPIN HEALTHCARE SYSTEM, INC. (HHS). HHS IS A PUBLIC CORPORATION AND SUBSIDIARY OF HENNEPIN COUNTY, MINNESOTA. HHS UTILIZES A COMPENSATION COMMITTEE, AN INDEPENDENT COMPENSATION CONSULTANT, A COMPENSATION SURVEY OR STUDY, AND APPROVAL BY THE COMPENSATION COMMITTEE TO DETERMINE SUCH COMPENSATION.

Schedule J (Form 990) (Rev. 1-2025)

Additional Data

Software ID:
Software Version:

- TIN:

SCHEDULE O
(Form 990)
(Rev. January 2025)
Department of the Treasury
Internal Revenue Service

Supplemental Information to Form 990 or 990-EZ

Complete to provide information for responses to specific questions on
Form 990 or 990-EZ or to provide any additional information.
Attach to Form 990 or 990-EZ.
Go to www.irs.gov/Form990 for instructions and the latest information.

OMB No. 1545-0047

Open to Public
Inspection

Name of the organization

HENNEPIN HEALTHCARE RESEARCH INSTITUTE

Employer identification number

41-1677920

Return Reference	Explanation
FORM 990, PART III, LINES 4A AND 4B:	AT THE HENNEPIN HEALTHCARE RESEARCH INSTITUTE (HHRI), OUR INVESTIGATORS HAVE BEEN TRANSLATING SCIENTIFIC KNOWLEDGE INTO DISCOVERIES THAT MAKE A DIFFERENCE SINCE 1952. WE ACTIVELY INVESTIGATE THE CAUSES OF AND POTENTIAL TREATMENTS FOR DISEASES, GUIDED BY OUR GOALS OF ADVANCING MEDICAL KNOWLEDGE AND OUR MISSION OF IMPROVING PATIENT CARE AND THE HEALTH OF OUR COMMUNITY THROUGH RESEARCH AND EDUCATION. HHRI IS PART OF HENNEPIN HEALTHCARE, AN INTEGRATED SYSTEM OF CARE THAT INCLUDES HCMC, A NATIONALLY RECOGNIZED LEVEL 1 ADULT AND PEDIATRIC TRAUMA CENTER AND AN ESSENTIAL TEACHING AND SAFETY NET HOSPITAL. HHRI SUPPORTS AND OVERSEES THE MEDICAL RESEARCH CARRIED OUT AT HCMC. THE WIDE-RANGE OF MEDICAL SPECIALTIES HCMC OFFERS AND A DIVERSE PATIENT POPULATION ENABLE HHRI INVESTIGATORS TO ESTABLISH CROSS-FUNCTIONAL COLLABORATIONS TO EXPLORE NEW AND INNOVATIVE WAYS TO UNDERSTAND AND TREAT DISEASE. HHRI IS ONE OF THE LARGEST NONPROFIT MEDICAL RESEARCH ORGANIZATIONS IN MINNESOTA. IT SUPPORTS THE WORK OF MORE THAN 200 RESEARCH STAFF AND INVESTIGATORS (MDS, MD/PHDS, PHDS AND PHARMDS). IN 2024, HHRI RECEIVED 151 NEW OR RENEWING SPONSORED AWARDS WITH OVER 75% OF FUNDING COMING FROM STATE AND FEDERAL GOVERNMENTS. FUNDING ALSO CAME FROM PRIVATE FOUNDATIONS, INDUSTRY PARTNERS, AND CORPORATE AND INDIVIDUAL DONATIONS. HHRI CONSISTENTLY RANKS NATIONALLY IN THE TOP 10% OF INSTITUTIONS RECEIVING FUNDING FROM THE NATIONAL INSTITUTES OF HEALTH (NIH). HHRI RESEARCHERS ARE EXPERTS IN THEIR FIELDS TACKLING OUR BIGGEST HEALTHCARE CHALLENGES, INCLUDING HIV/AIDS, SUBSTANCE USE DISORDERS, LIFE-THREATENING AND TIME-SENSITIVE CONDITIONS, CHRONIC DISEASES, AND ACCESS TO CARE. THEY CONDUCT BASIC, TRANSLATIONAL, CLINICAL, AND EPIDEMIOLOGIC RESEARCH WITH A FOCUS ON ACUTE CARE/TRAUMA, ADDICTION, HEALTH SERVICES, AND INFECTIOUS DISEASES. IN 2024, HHRI RESEARCHERS MADE SIGNIFICANT CONTRIBUTIONS TO THE STUDY AND PRACTICE OF MEDICINE IN THE FOLLOWING SPECIALTIES: ACUTE CARE/TRAUMA - CARDIAC BIOMARKERS - CARDIOPULMONARY RESUSCITATION - EMERGENCY MEDICINE - FROSTBITE AND BURN - INFECTIOUS DISEASES / SEPSIS - NEUROSURGERY - ORTHOPAEDICS - PULMONARY AND CRITICAL CARE MEDICINE - TRAUMA AND CRITICAL CARE - TRAUMA AND SURGICAL CRITICAL CARE - TRAUMATIC BRAIN INJURY (TBI) - TBI AND CORTICAL SPREADING DEPOLARIZATION (CSD) ADDICTION - ADDICTION MEDICINE - OPIOID TREATMENT RESEARCH - REDUCING THE IMPACT OF TOBACCO-RELATED DISEASES - TOBACCO CESSATION / BEHAVIOR HEALTH - TOBACCO TREATMENT RESEARCH HEALTH SERVICES - BRAIN HEALTH AND CEREBROVASCULAR CARE - CLINICAL OUTCOMES RESEARCH - CANCER - CHILDREN'S ISSUES - CHRONIC DISEASES - DEMENTIA AND AGING - DIABETES AND OBESITY - HEALTH, HOMELESSNESS, AND CRIMINAL JUSTICE - KIDNEY DISEASE - NEPHROLOGY, TRANSPLANTATION AND HEALTH DISPARITIES AND PHARMACOGENOMICS - NEUROLOGY, ALS, AND NEUROPALLIATIVE CARE - ORGAN TRANSPLANTATION INFECTIOUS DISEASES - COVID-19 - HIV / AIDS - HEPATITIS B AND C - IMMUNE THERAPY AND IMMUNOLOGY - MALARIA IMMUNOLOGY - SEXUALLY TRANSMITTED INFECTIONS, HIV PREVENTION THE MAJORITY OF OUR RESEARCH PROJECTS ARE TRANSLATIONAL IN NATURE. TRANSLATIONAL RESEARCH SEEKS TO TAKE DISCOVERIES MADE IN A LABORATORY SETTING AND TRANSLATE THEM INTO THERAPIES PHYSICIANS CAN USE IN THEIR MEDICAL PRACTICES TO IMPROVE THE LIVES OF PATIENTS LOCALLY AND AROUND THE GLOBE. IN AN ENVIRONMENT THAT EMPHASIZES PATIENT CARE, RESEARCH AND TEACHING, HHRI IS AT THE FOREFRONT OF DISCOVERING SOLUTIONS TO SOME OF THE MOST COMPLEX MEDICAL PROBLEMS. THE WORK OF OUR INVESTIGATORS IS ADVANCING MEDICINE TO ENSURE A HEALTHIER TOMORROW FOR ALL MEMBERS OF OUR COMMUNITY. FOR MORE INFORMATION ABOUT HHRI VISIT OUR WEBSITE AT WWW.HHRINSTITUTE.ORG.
FORM 990, PART VI, SECTION A, LINE 1A	THE HENNEPIN HEALTHCARE RESEARCH INSTITUTE (HHRI) EXECUTIVE COMMITTEE OF THE BOARD IS COMPRISED OF FIVE HHRI DIRECTORS: CONNIE DELANEY, PHD, RN, FAAN, FACMI, FNAP, MIAJA CASSIDY, J.D., CHC, CCEP, SERAFIN SAMSON, MBA, M.S., KIRSTEN JOHANSEN, M.D., AND WARREN MCKINNEY, PHD. THE COMMITTEE IS DESIGNATED BY THE HHRI DIRECTORS AND SHALL HAVE THE AUTHORITY OF THE BOARD OF DIRECTORS IN THE MANAGEMENT OF THE BUSINESS OF THE ORGANIZATION IN THE INTERVAL BETWEEN MEETINGS OF THE BOARD OF DIRECTORS, AND THE EXECUTIVE COMMITTEE SHALL AT ALL TIMES BE SUBJECT TO THE CONTROL AND DIRECTION OF THE BOARD OF DIRECTORS.
FORM 990, PART VI, SECTION A, LINE 6	HENNEPIN HEALTHCARE SYSTEM INC. (HHS), A RELATED ORGANIZATION, IS THE SOLE MEMBER OF THE HENNEPIN HEALTHCARE RESEARCH INSTITUTE (HHRI). HHS IS A PUBLIC CORPORATION AND SUBSIDIARY OF HENNEPIN COUNTY, MINNESOTA, AND OPERATES AND CONDUCTS BUSINESS AS HENNEPIN COUNTY MEDICAL CENTER (HCMC).
FORM 990, PART VI, SECTION A, LINE 7A	THE HENNEPIN HEALTHCARE RESEARCH INSTITUTE (HHRI) BOARD OF DIRECTORS INCLUDES WHEN POSSIBLE: ONE MEMBER OF THE BOARD OF DIRECTORS OF HENNEPIN HEALTHCARE SYSTEM, INC. (HHS) DESIGNATED BY THE HHS BOARD; TWO DIRECTORS DESIGNATED BY THE HHS CEO FROM AMONG THE EXECUTIVE EMPLOYEES OF HHS; AND ADDITIONAL DIRECTORS NOMINATED BY THE HHRI BOARD AND ELECTED BY THE HHS BOARD.
FORM 990, PART VI, SECTION A, LINE 7B	PURSUANT TO SECTION 3.1 OF THE BYLAWS OF THE HENNEPIN HEALTHCARE RESEARCH INSTITUTE (HHRI), HHRI MAY NOT TAKE ANY OF THE FOLLOWING ACTIONS WITHOUT RECEIVING HENNEPIN HEALTHCARE SYSTEM, INC. (HHS) APPROVAL IN ACCORDANCE WITH PROCEDURES ESTABLISHED BY HHS'S STATUTORY CHARTER AND BYLAWS: APPROVAL OF NOMINEES AND ADDITION OF MEMBERS TO CORPORATION'S BOARD OF DIRECTORS; ADOPTION OF ANNUAL OR LONG-RANGE FINANCIAL PLANS; ADOPTION OF ANNUAL OPERATING BUDGETS; ADOPTION OF ANNUAL CAPITAL BUDGETS; ADOPTION OR SUBSTANTIAL MODIFICATION OF COMPENSATION OR FRINGE BENEFIT PROGRAMS; INCURRENCE OF DEBT; MORTGAGE OR ENCUMBRANCE OF ANY ASSET; SALE, LEASE, OR OTHER DISPOSITION OF ALL, OR SUBSTANTIALLY ALL, OF CORPORATION'S PROPERTY AND ASSETS; AMENDMENT OF CORPORATION'S ARTICLES OF INCORPORATION OR BYLAWS; AND MERGER OR CONSOLIDATION WITH ANY DOMESTIC OR FOREIGN ORGANIZATION AND VOLUNTARY DISSOLUTION OF THE CORPORATION.
FORM 990, PART VI, SECTION B, LINE 11B	THE PROCESS HENNEPIN HEALTHCARE RESEARCH INSTITUTE (HHRI) USES FOR REVIEW OF THE ANNUAL FORM 990 BEFORE THE FORM IS SENT TO THE IRS INCLUDES AN INITIAL REVIEW BY THE CHIEF FINANCIAL OFFICER AND CHIEF OPERATING OFFICER. THE FORM IS THEN SENT TO OUR AUDIT FIRM FOR FURTHER REVIEW AND ANALYSIS. PRIOR TO THE FORM 990 BEING SENT TO THE IRS, THE FORM IS REVIEWED AND APPROVED BY THE FINANCE AND AUDIT COMMITTEE AND THEN SENT EITHER ELECTRONICALLY OR IN PAPER FORM TO OUR BOARD MEMBERS AND IS PRESENTED TO THE BOARD AT THE NEXT AVAILABLE MEETING TO DISCUSS AND APPROVE THE CONTENTS OF THE FORM.
FORM 990, PART VI, SECTION B, LINE 12C	SEE BELOW ON SCHEDULE O FOR CONFLICT OF INTEREST POLICY STATEMENTS.
FORM 990, PART VI, SECTION B, LINE 15A	THE PROCESS FOR DETERMINING COMPENSATION FOR THE HENNEPIN HEALTHCARE RESEARCH INSTITUTE (HHRI) VICE-PRESIDENT OF OPERATIONS AND CHIEF OPERATING OFFICER, INCLUDES THE OPERATIONS COMMITTEE REVIEWING PERFORMANCE AND COMPENSATION INFORMATION FOR COMPARABLE POSITIONS AT SIMILAR LOCATIONS INCLUDING SALARY SURVEY INFORMATION FROM THE UNIVERSITY OF MINNESOTA AND MINNESOTA COUNCIL OF NONPROFITS. MINUTES OF THE OPERATIONS COMMITTEE AND SUBSEQUENT BUDGET APPROVAL BY THE FULL BOARD ARE ON FILE. THIS PROCESS WAS LAST UNDERTAKEN IN 2024. THE COMPENSATION FOR THE HHRI PRESIDENT AND VICE-PRESIDENT IS PAID BY A RELATED ORGANIZATION, HENNEPIN HEALTHCARE SYSTEM INC. (HHS), WHICH IS A PUBLIC CORPORATION AND SUBSIDIARY OF HENNEPIN COUNTY, MINNESOTA, AND OPERATES AND CONDUCTS BUSINESS AS HENNEPIN COUNTY MEDICAL CENTER (HCMC). HHS HAS AN ESTABLISHED POLICY AND PROCEDURE FOR DETERMINING COMPENSATION. THE PROCESS DESCRIBED HERE WAS LAST COMPLETED IN 2024.
FORM 990, PART VI, SECTION C, LINE 19	GOVERNANCE DOCUMENTS ARE AVAILABLE UPON REQUEST.
FORM 990, PART VI, SECTION B, LINE 12C (CONTINUED):	THE PURPOSE OF THIS POLICY IS TO ENABLE AND FACILITATE THE RESEARCH AND EDUCATION MISSIONS OF THE HHRI (INSTITUTION) BY ASSURING THEIR OBJECTIVITY AND INDEPENDENCE FROM COMPETING FINANCIAL INTERESTS. THE STAKEHOLDERS CONSIDERED IN THIS POLICY ARE THE PUBLIC, OUR PATIENTS AND RESEARCH SUBJECTS, THE SCIENTIFIC COMMUNITY, THE AGENCIES WHO FUND OUR ACTIVITIES, AND OUR FACULTY, STAFF AND TRAINEES. AN EQUALLY COMPELLING PURPOSE IS TO MAINTAIN COMPLIANCE WITH ALL APPLICABLE FEDERAL AND STATE LAWS AND REGULATIONS RELATED TO CONFLICTS OF INTERESTS AND WITH THE POLICIES AND REQUIREMENTS OF THE REGULATORY AGENCIES WHICH OVERSEE OUR ACTIVITIES, INCLUDING BUT NOT LIMITED TO THE UNITED STATES PUBLIC HEALTH SERVICE (USPHS) AND FEDERAL DRUG ADMINISTRATION (FDA) (42CFR50 AND 21CFR54.2). CONFLICT OF INTEREST. THE SPECIFIC GOAL OF THIS POLICY IS TO ADDRESS FINANCIAL CONFLICTS OF INTEREST (FCOI). FOR THIS POLICY, FINANCIAL CONFLICT OF INTEREST REFERS TO COMPETING FINANCIAL INTERESTS OR INCENTIVES. SPECIFICALLY, IT IS A SITUATION IN WHICH A COVERED INDIVIDUAL (SEE DEFINITIONS, PAGE 12) HAS A RELATIONSHIP WITH AN EXTERNAL ENTITY THAT MAY CREATE FINANCIAL INCENTIVES THAT MAY COMPETE WITH HIS/HER ACADEMIC OR PROFESSIONAL INTERESTS, OBLIGATIONS, OR INSTITUTIONAL RESPONSIBILITIES. A CONFLICT OF INTEREST DOES NOT IMPLY WRONG-DOING OR IMPROPER RELATIONSHIPS, BUT DOES REQUIRE DISCLOSURE, EVALUATION AND SOMETIMES MITIGATION. IN ACCORDANCE WITH APPLICABLE FEDERAL REGULATION NOTED ABOVE, THIS POLICY IS INTENDED TO PROTECT THE DESIGN, CONDUCT AND REPORTING OF RESEARCH CONDUCTED BY HHRI (INCLUDING WORK FUNDED UNDER PHS/NIH GRANTS OR COOPERATIVE AGREEMENTS) FROM BIAS RESULTING FROM FCOIS OF COVERED INDIVIDUALS. APPEARANCE OF CONFLICT OF INTEREST. SOME SITUATIONS FALL OUTSIDE THE DEFINITION OF COI BUT MAY RAISE QUESTIONS IN THE MIND OF A REASONABLE OBSERVER WHICH ARE BEST ADDRESSED IN ORDER TO ASSURE THAT THE SITUATION HAS BEEN CONSIDERED (SEE APPENDIX I, HCMC CODE OF CONDUCT FOR ADDITIONAL INFORMATION). THE COI COMMITTEE RESERVES THE RIGHT TO INCLUDE SUCH ISSUES OF APPEARANCE IN ITS DELIBERATIONS AND APPROACHES TO MANAGING THE FINANCIAL RELATIONSHIPS OF INVESTIGATORS. THIS POLICY IS APPLICABLE TO: - ALL PERSONS APPOINTED, EMPLOYED BY OR COMPENSATED BY THE HHRI; - ALL PERSONS ENGAGED IN THE CONDUCT OF RESEARCH ACTIVITIES UNDER THE AUSPICES OF THE HHRI WHO ARE IN A POSITION TO INFLUENCE THE DESIGN, CONDUCT OR REPORTING OF RESEARCH OR OTHER SCHOLARLY ACTIVITY; THIS INCLUDES "INVESTIGATORS" AS DEFINED BY 42CFR50.603 WHICH MEANS THE PROJECT DIRECTOR OR PRINCIPAL INVESTIGATOR OF ANY PHS PROPOSED OR FUNDED RESEARCH AND ANY OTHER PERSON, REGARDLESS OF TITLE OR POSITION, WHO IS RESPONSIBLE FOR THE DESIGN, CONDUCT, OR REPORTING OF RESEARCH FUNDED BY THE PHS, OR PROPOSED FOR SUCH FUNDING, WHICH MAY INCLUDE, FOR EXAMPLE, COLLABORATORS OR CONSULTANTS. - ALL PERSONS WHO HAVE DIRECT INFLUENCE OVER PURCHASING DECISIONS OR CONTRACTS MADE ON BEHALF OF HHRI; - ALL HOLDERS OF HHRI RESEARCH AND EDUCATION ACCOUNTS; - ALL MEMBERS OF HHRI'S BOARD OF DIRECTORS, MEMBERS OF HHRI'S CONFLICT OF INTEREST COMMITTEE, AND MEMBERS OF REGULATORY COMMITTEES INCLUDING THE IRB, IACUC AND THE IBC; - FOR PURPOSES OF REPORTING FINANCIAL INTERESTS UNDER THIS POLICY, COVERED INDIVIDUALS ALSO INCLUDE A SPOUSE OR DOMESTIC PARTNER, AND DEPENDENT CHILDREN. COVERED INDIVIDUALS AT HHRI MUST COMPLY WITH HHRI'S POLICY ON CONFLICT OF INTEREST AND ALL APPLICABLE FEDERAL AND STATE LAWS RELATED TO CONFLICT OF INTEREST AND SHALL NOT ENGAGE IN ACTIVITIES THAT COMPROMISE THEIR PROFESSIONAL JUDGMENT OR COMPETE WITH THE FULFILLMENT OF THEIR OBLIGATIONS TO HHRI. RELATIONSHIPS CONSTITUTING A POTENTIAL COI MUST BE REPORTED TO THE HHRI COI COMMITTEE PRIOR TO THEIR INITIATION. CHANGES IN EXISTING RELATIONSHIPS MUST ALSO BE REPORTED BEFORE THE CHANGES TAKE PLACE. THE PURPOSE OF THIS REQUIREMENT IS TO AVOID COI WHEN POSSIBLE, OR TO MAKE ALL PARTIES AWARE OF THE PROPOSED RELATIONSHIP AND ANY POSSIBLE MITIGATION REQUIREMENTS. COVERED INDIVIDUALS MAY NOT PARTICIPATE IN RELATIONSHIPS WITH BUSINESS ENTITIES THAT: - RESULT IN PAYMENTS TO THE COVERED INDIVIDUAL WHICH ARE INTENDED TO INFLUENCE HOW THE COVERED INDIVIDUAL CONDUCTS INSTITUTIONAL ACTIVITIES; - CONSTITUTE GHOST WRITING (HAVING ONE'S NAME AND INSTITUTIONAL AFFILIATION ASSOCIATED WITH A PUBLICATION OR OTHER ARTICLE WHERE THE COVERED INDIVIDUAL HAS NO SUBSTANTIAL INPUT INTO THE PUBLICATION OR ARTICLE). AUTHORSHIP SHOULD BE RESTRICTED TO THOSE INDIVIDUALS WHO MEET THE FOLLOWING CRITERIA: - MADE A SIGNIFICANT CONTRIBUTION TO THE CONCEPTUALIZATION AND/OR DESIGN OR CONDUCT OF THE PROJECT; - PARTICIPATED IN THE ANALYSIS AND INTERPRETATION OF THE DATA, OR OTHER SUBSTANTIAL SCHOLARLY WORK; - PARTICIPATED IN DRAFTING, REVIEWING AND/OR REVISING THE WORK; AND - APPROVED THE FINAL VERSION OF PUBLICATION. - INVOLVE THE COVERED INDIVIDUAL'S ENDORSEMENT OF A PRODUCT OR SERVICE DEVELOPED AND/OR SOLD BY A PARTICULAR BUSINESS. THIS APPLIES TO BOTH WRITTEN AND ORAL ENDORSEMENTS WHEN THE PRODUCT OR SERVICE RELATES TO THE COVERED INDIVIDUAL'S INSTITUTION- RELATED EXPERTISE AND/OR INSTITUTIONAL ACTIVITIES, WHETHER OR NOT THE INDIVIDUAL USES HIS OR HER INSTITUTIONAL TITLE IN MAKING THE ENDORSEMENT; - INVOLVE ACCEPTANCE OF GIFTS OF ANY AMOUNT OR VALUE FROM INDUSTRY DOING BUSINESS OR SEEKING TO DO BUSINESS WITH THE HHRI. EXAMPLES INCLUDE BUT ARE NOT LIMITED TO PENS, PADS, OTHER PROMOTIONAL ITEMS, CASH, FOOD AND DRINK, ENTERTAINMENT SUCH AS TICKETS TO EVENTS, GOLF AND OTHER SPORTS OUTINGS, MEDICAL OR RESEARCH EQUIPMENT, DEVICES OR OTHER PRODUCTS OR SERVICES OR DISCOUNTS ON SAME, USE OF COMPANY VEHICLES OR VACATION FACILITIES, HOTELS, TRANSPORTATION AND OTHER TRAVEL EXPENSES, STOCKS, EQUITY, AND OTHER SUCH FINANCIAL OFFERINGS, GROUP GIFTS, TEXTBOOKS, BIOLOGICAL SAMPLES, SOFTWARE, COMPUTER HARDWARE AND ACCESSORIES, ELECTRONIC DEVICES SUCH AS CELL PHONES, PAGERS, MUSIC AND VIDEO PLAYERS, PDA'S CONSULTING, FINANCIAL AND OTHER SERVICES AND OFFICE AND RESEARCH SUPPLIES. IT IS RECOGNIZED THAT THERE ARE CIRCUMSTANCES WHEN INDIVIDUALS HAVE NO CONTROL OVER RECEIPT OF GIFTS AND MAY INADVERTENTLY VIOLATE THIS POLICY, SUCH AS ATTENDANCE AT INDUSTRY SPONSORED PROFESSIONAL MEETINGS WHERE A MANDATORY LUNCH IS PROVIDED AND THERE IS NO PRACTICAL ALTERNATIVE. COVERED INDIVIDUALS MUST REPORT ALL EXTERNAL RELATIONSHIPS ANNUALLY. THE DEFINITIONS OF SIGNIFICANCE PROVIDED THROUGHOUT THIS POLICY PROVIDE THE REGULATORY BASES FOR DISCLOSURE, REPORTING, AND MANAGEMENT OF FINANCIAL CONFLICTS OF INTEREST THAT HHRI MUST ADHERE TO AND ENFORCE AS A RECIPIENT OF PUBLIC HEALTH SERVICE (PHS) FUNDING. HOWEVER, THE INSTITUTION'S DISCLOSURE THRESHOLD IS MORE RESTRICTIVE SINCE IT DOESN'T HAVE MINIMUM THRESHOLDS FOR DISCLOSURE ALL EXTERNAL FINANCIAL INTERESTS MUST BE DISCLOSED. ANNUAL REPORTING IS INTENDED TO BE INCLUSIVE OF ALL FINANCIAL RELATIONSHIPS AND NOT CONFINED TO RELATIONSHIPS RELEVANT TO SPECIFIC ONGOING OR PROPOSED PROJECTS. IN ADDITION, WHEN PROPOSING OR CONDUCTING A SPECIFIC RESEARCH PROJECT, INVESTIGATORS MUST IDENTIFY ANY FINANCIAL INTERESTS RELATED TO THAT SPECIFIC RESEARCH PROJECT (VIA THE COMPLIANCE COMMITTEE STANDARDIZED REPORTING FORM) TO ENSURE THAT NO ARRANGEMENT HAS BEEN ENTERED INTO WHEREBY THE VALUE OF AN OWNERSHIP INTEREST WILL BE AFFECTED BY THE OUTCOME OF THE RESEARCH. THIS INCLUDES ANY FINANCIAL INTERESTS IN THE SPONSOR, PRODUCT OR SERVICE BEING TESTED, OR IN ANY DIRECT COMPETITOR OF THE SPONSOR, PRODUCT OR SERVICE BEING TESTED. THIS REPORTING WILL BE DONE VIA THE COMPLIANCE COMMITTEE STANDARDIZED REPORTING FORM FOUND IN APPLICATION MATERIALS FOR THE IRB, IACUC, AND IBC AND IN THE GRANT AND CONTRACT APPLICATION FOR EXTERNAL SUPPORT. NEW FINANCIAL INTERESTS AND SUBSTANTIAL CHANGES IN A FINANCIAL OR BUSINESS INTEREST (SEE DEFINITIONS, PAGE 12) MUST BE REPORTED WITHIN 30 DAYS OF ACQUISITION OR DISCOVERY. HHRI WILL TAKE ACTION TO REVIEW REPORTED INTERESTS, MAKE A DETERMINATION OF WHETHER THE INTEREST IS RELATED TO PHS/NIH-FUNDED RESEARCH (I.E., THE SFI COULD BE AFFECTED BY THE RESEARCH OR IS IN AN ENTITY WHOSE FINANCIAL INTEREST COULD BE AFFECTED BY THE RESEARCH) AND REPRESENTS AN FCOI (I.E., COULD DIRECTLY AND SIGNIFICANTLY AFFECT THE DESIGN, CONDUCT OR REPORTING OF PHS/NIH-FUNDED RESEARCH), AND REPORT FCOIS TO THE NATIONAL INSTITUTES OF HEALTH (NIH) WITHIN 60 DAYS OF DISCLOSURE IF THE INTEREST IS RELATED TO AN NIH SUPPORTED PROJECT. IN ORDER TO MAKE CONFLICT INFORMATION AVAILABLE TO COLLEAGUES, COLLABORATORS, TRAINEES AND RESEARCH SUBJECTS, CERTAIN INFORMATION REGARDING THE CONFLICT SITUATION SHALL BE MADE AVAILABLE VIA A PUBLICLY ACCESSIBLE WEB SITE OR WRITTEN RESPONSE TO ANY REQUESTOR WITHIN FIVE BUSINESS DAYS OF A REQUEST. THIS SHALL INCLUDE, AT A MINIMUM, THE FOLLOWING: THE INVESTIGATOR'S NAME; THE INVESTIGATOR'S TITLE AND ROLE WITH RESPECT TO THE RESEARCH PROJECT; THE NAME OF THE ENTITY IN WHICH THE SIGNIFICANT FINANCIAL INTEREST IS HELD; THE NATURE OF THE
FORM 990, PART VI, SECTION B, LINE 12C (CONTINUED):	SIGNIFICANT FINANCIAL INTEREST; AND THE APPROXIMATE DOLLAR VALUE OF THE INTEREST, OR A STATEMENT THAT THE INTEREST IS ONE WHOSE VALUE CANNOT BE READILY DETERMINED THROUGH REFERENCE TO PUBLIC PRICES OR OTHER REASONABLE MEASURES OF FAIR MARKET VALUE. THIS INFORMATION SHALL BE MADE AVAILABLE PRIOR TO THE EXPENDITURE OF ANY FEDERAL FUNDS AND WILL BE UPDATED AT LEAST ANNUALLY OR WITHIN 60 DAYS OF DISCLOSURE OF A NEWLY IDENTIFIED FINANCIAL CONFLICT OF INTEREST. THE INFORMATION WILL REMAIN AVAILABLE FOR AT LEAST THREE YEARS FROM THE DATE THAT THE INFORMATION WAS MOST RECENTLY UPDATED. WHERE A CONFLICT OF INTEREST IS IDENTIFIED, THE COVERED INDIVIDUAL MAY BE REQUIRED TO FOLLOW AN APPROVED CONFLICT MITIGATION PLAN THAT PROVIDES MECHANISMS TO MANAGE, REDUCE OR ELIMINATE THE CONFLICT. WHEN COVERED INDIVIDUALS PARTICIPATE IN SPONSORED RESEARCH INVOLVING SUB-GRANTEES, CONTRACTORS OR COLLABORATORS OUTSIDE THE INSTITUTION, HHRI WILL TAKE REASONABLE STEPS TO ENSURE THAT THESE OUTSIDE ASSOCIATES COMPLY WITH APPROPRIATE CONFLICT OF INTEREST REPORTING, DISCLOSURE, REVIEW AND MANAGEMENT PLAN REQUIREMENTS. APPROPRIATE DISCIPLINARY ACTION MAY BE TAKEN BY THE HHRI AGAINST COVERED INDIVIDUALS WHO VIOLATE THIS POLICY. WHENEVER A FINANCIAL CONFLICT OF INTEREST IS NOT IDENTIFIED OR MANAGED IN A TIMELY MANNER, INCLUDING: - FAILURE BY THE INVESTIGATOR TO DISCLOSE A SIGNIFICANT FINANCIAL INTEREST THAT IS DETERMINED BY THE INSTITUTION TO CONSTITUTE A FINANCIAL CONFLICT OF INTEREST; - FAILURE BY THE INSTITUTION TO REVIEW OR MANAGE SUCH A FINANCIAL CONFLICT OF INTEREST; OR - FAILURE BY THE INVESTIGATOR TO COMPLY WITH A FINANCIAL CONFLICT OF INTEREST MANAGEMENT PLAN; THE INSTITUTION SHALL, WITHIN 120 DAYS OF THE INSTITUTION'S DETERMINATION OF NONCOMPLIANCE, COMPLETE A "RETROSPECTIVE REVIEW" OF THE INVESTIGATOR'S ACTIVITIES AND THE NIH SUPPORTED RESEARCH PROJECT TO DETERMINE WHETHER ANY NIH SUPPORTED RESEARCH, OR PORTION THEREOF, CONDUCTED DURING THE TIME PERIOD OF THE NONCOMPLIANCE WAS BIASED IN THE DESIGN, CONDUCT, OR REPORTING OF SUCH RESEARCH. HHRI WILL DOCUMENT THE RETROSPECTIVE REVIEW WHICH WILL INCLUDE AT LEAST THE FOLLOWING KEY ELEMENTS: - SPONSOR TYPE, NAME, AND PROJECT NUMBER; - PROJECT TITLE; - PD/PI OR CONTACT PD/PI IF A MULTIPLE PD/PI MODEL IS USED; - NAME OF THE INVESTIGATOR WITH THE FCOI; - NAME OF THE ENTITY WITH WHICH THE INVESTIGATOR HAS A FINANCIAL CONFLICT OF INTEREST - REASON(S) FOR THE RETROSPECTIVE REVIEW; - DETAILED METHODOLOGY USED FOR THE RETROSPECTIVE REVIEW (E.G., METHODOLOGY OF THE REVIEW PROCESS, COMPOSITION OF THE REVIEW PANEL, DOCUMENTS REVIEWED, ETC.); - FINDINGS OF THE REVIEW; AND - CONCLUSIONS OF THE REVIEW. IF BIAS IS FOUND RELATED TO AN NIH SUPPORTED PROJECT, THE HHRI WILL NOTIFY NIH PROMPTLY AND SUBMIT A MITIGATION REPORT. IF THE FCOI WAS PREVIOUSLY REPORTED TO THE NIH, THE MITIGATION REPORT WILL BE SUBMITTED AS A "REVISED FCOI REPORT." THE MITIGATION REPORT WILL INCLUDE, AT A MINIMUM, THE KEY ELEMENTS DOCUMENTED IN THE RETROSPECTIVE REVIEW ABOVE AND A DESCRIPTION OF THE IMPACT OF THE BIAS ON THE RESEARCH PROJECT AND THE HHRI'S PLAN OF ACTION OR ACTIONS TAKEN TO ELIMINATE OR MITIGATE THE EFFECT OF THE BIAS (I.E., IMPACT ON THE RESEARCH PROJECT, EXTENT OF HARM DONE, INCLUDING ANY QUALITATIVE AND QUANTITATIVE DATA TO SUPPORT ANY ACTUAL OR FUTURE HARM; ANALYSIS OF WHETHER THE RESEARCH PROJECT IS SALVAGEABLE). THEREAFTER, HHRI WILL SUBMIT FCOI REPORTS ANNUALLY AS PRESCRIBED BY APPLICABLE REGULATION. OTHER DISCIPLINARY ACTIONS, IN ADDITION TO RETRAINING AND/OR ANY LEGAL PENALTY(IES), MAY INCLUDE ORAL ADMONISHMENT, WRITTEN REPRIMAND, OR REASSIGNMENT, DEMOTION, SUSPENSION, OR TERMINATION. INVESTIGATORS MAY ALSO BE PROHIBITED FROM FURTHER GRANT OR CONTRACT PROPOSAL SUBMISSION OR PARTICIPATION IN RESEARCH ACTIVITIES. AS OUTLINED ABOVE, POLICY VIOLATIONS THAT INVOLVE PUBIC HEALTH SERVICE (PHS) SUPPORTED PROJECTS SHALL BE REPORTED TO A RESPONSIBLE GRANTEE OFFICIAL AND SHALL SPECIFY THE TYPE OF ADMINISTRATIVE ACTION TAKEN INCLUDING REQUESTING DISCLOSURE ADDENDUMS TO PREVIOUSLY PUBLISHED PAPERS IF NECESSARY. POLICY VIOLATIONS THAT INVOLVE OTHER SPONSORED FUNDS SHALL BE REPORTED TO THE SPONSOR AS DIRECTED BY THE TERMS AND CONDITIONS OF THE AWARD. ALL FINANCIAL CONFLICT OF INTEREST RECORDS SHALL BE MAINTAINED FOR AT LEAST THREE YEARS FROM THE DATE A FINAL EXPENDITURE REPORT IS SUBMITTED FOR THE PROJECT OR FROM OTHER DATES AS SPECIFIED IN THE AWARD DOCUMENT OR CONTRACT. THIS INCLUDES ALL RECORDS OF ALL INVESTIGATOR DISCLOSURES OF FINANCIAL INTERESTS AND THE INSTITUTION'S REVIEW OF, OR RESPONSE TO, SUCH DISCLOSURE (WHETHER OR NOT A DISCLOSURE RESULTED IN THE INSTITUTION'S DETERMINATION OF A FINANCIAL CONFLICT OF INTEREST), AND ALL ACTIONS UNDER THE INSTITUTION'S POLICY OR RETROSPECTIVE REVIEW, IF APPLICABLE, AS FOLLOWS: - RECORDS OF FINANCIAL DISCLOSURES AND ANY RESULTING ACTION WILL BE MAINTAINED BY THE INSTITUTION FOR AT LEAST THREE YEARS FROM THE DATE OF SUBMISSION OF THE FINAL EXPENDITURES REPORT OR, WHERE APPLICABLE, FROM OTHER DATES SPECIFIED IN 45 C.F.R. 75.361, AS APPLICABLE, WHICH INCLUDES THE FOLLOWING EXCEPTIONS: - IF ANY LITIGATION, CLAIM, OR AUDIT IS STARTED BEFORE THE EXPIRATION OF THE 3-YEAR PERIOD, THE RECORDS WILL BE RETAINED UNTIL ALL LITIGATION, CLAIMS, OR AUDIT FINDINGS INVOLVING THE RECORDS HAVE BEEN RESOLVED AND FINAL ACTION TAKEN. - WHEN HHRI IS NOTIFIED IN WRITING BY AN HHS AWARDING AGENCY, COGNIZANT AGENCY FOR AUDIT, OVERSIGHT AGENCY FOR AUDIT, COGNIZANT AGENCY FOR INDIRECT COSTS, OR PASS-THROUGH ENTITY TO EXTEND THE RETENTION PERIOD. - WHEN RECORDS ARE TRANSFERRED TO OR MAINTAINED BY THE HHS AWARDING AGENCY OR A PASS-THROUGH ENTITY, THE 3-YEAR RETENTION REQUIREMENT IS NOT APPLICABLE. TRAINING ALL PERSONS ENGAGED IN RESEARCH UNDER THE AUSPICES OF THE HHRI ARE REQUIRED TO COMPLETE TRAINING IN COI PRIOR TO ENGAGING IN ANY RESEARCH THAT INVOLVES HUMAN OR ANIMAL RESEARCH SUBJECTS AND AT LEAST EVERY FOUR YEARS THEREAFTER (OR IN THE CASE OF NIH SUPPORTED RESEARCH BY THE ISSUE DATE OF THE NOTICE OF AWARD OR WITHIN THIRTY DAYS OF BEING NEW TO THE INSTITUTION). IN ADDITION TO THE REQUIRED COI TRAINING NOTED ABOVE, ANY COVERED PERSON DETERMINED TO BE NON-COMPLIANT WITH THE INSTITUTIONAL COI POLICY OR DETERMINATIONS OF THE COI COMMITTEE WILL BE REQUIRED TO REPEAT COI TRAINING IMMEDIATELY (NO LATER THAN 30 DAYS FROM NOTICE OF NON-COMPLIANCE). ADDITIONAL INFORMATION ABOUT INSTITUTIONAL REQUIREMENTS AND INSTRUCTIONS FOR COMPLETING COI TRAINING CAN BE FOUND IN THE HHRI SPONSORED PROGRAMS ADMINISTRATION GUIDANCE AND PROCEDURES MANUAL AND THE HHRI'S HUMAN RESEARCH PROTECTIONS PROGRAM INVESTIGATOR 501 MANUAL. REPORTING AND EVALUATING A COVERED INDIVIDUAL'S RELATIONSHIPS WITH EXTERNAL ENTITIES ON AN ANNUAL BASIS, ALL COVERED INDIVIDUALS MUST REPORT ALL CURRENT EXTERNAL RELATIONSHIPS AND/OR INTERESTS, THOSE THAT OCCURRED IN THE PREVIOUS YEAR, AND THOSE THAT CAN REASONABLY BE EXPECTED IN THE NEXT 12 MONTHS. FOR EXAMPLE, THE COVERED INDIVIDUAL MUST REPORT: - FINANCIAL AND / OR BUSINESS RELATIONSHIPS AND INTERESTS AND THOSE OF IMMEDIATE FAMILY MEMBERS WHICH RELATE TO OR COMPETE WITH THE COVERED INDIVIDUAL'S INSTITUTIONAL RESPONSIBILITIES INCLUDING, BUT NOT LIMITED TO, SALARY OR OTHER PAYMENTS FOR SERVICES (E.G., CONSULTING FEES OR HONORARIA); - EQUITY INTERESTS (E.G., STOCKS, WHETHER PUBLICLY TRADED OR NOT, STOCK OPTIONS, OR OTHER OWNERSHIP INTERESTS); - INTELLECTUAL PROPERTY RIGHTS (E.G., PATENTS, COPYRIGHTS AND ROYALTIES FROM SUCH RIGHTS); AND - OTHER ARRANGEMENTS UNDER WHICH FINANCIAL BENEFITS HAVE BEEN RECEIVED (E.G., GIFTS, LOANS OR SERVICES). - REIMBURSED OR SPONSORED TRAVEL REPORTING WILL CONSIST OF LISTING THE ENTITY WITH WHICH THE RELATIONSHIP EXISTS, OR IS ANTICIPATED IN THE NEXT 12 MONTHS, AND THE DOLLAR AMOUNT. THERE IS NO MINIMUM DOLLAR THRESHOLD FOR REPORTING; ALL COVERED FINANCIAL RELATIONSHIPS AND/OR INTERESTS MUST BE REPORTED. THE DOLLAR AMOUNT MAY BE REPORTED AS A RANGE: $0 TO $4,999 $5,000 $9,999 $10,000 $19,999 $20,000 $99,999 BY INCREMENTS OF $20K $100,000 $250,000 BY INCREMENTS OF $50,000 > $250,000 IF NEEDED TO ADEQUATELY EVALUATE OR MANAGE A CONFLICT, THE CONFLICT OF INTEREST COMMITTEE MAY ASK FOR MORE DETAILED INFORMATION, INCLUDING INFORMATION GOING BACK AS FAR AS THREE YEARS. OTHER RELATIONSHIPS AND/OR INTERESTS THAT FALL OUTSIDE OF THE SPECIFIC REPORTING GUIDELINES DESCRIBED HEREIN, SUCH AS THOSE OF A NON-BUSINESS OR NON-FINANCIAL NATURE (E.G., CLOSE FRIEND, IMMEDIATE OR EXTENDED FAMILY MEMBER SEE DEFINITIONS, PAGE 12), THAT MAY APPEAR TO CREATE A CONFLICT OF INTEREST OR THAT MIGHT INFLUENCE THE WAY A COVERED INDIVIDUAL ALLOCATES INSTITUTIONAL RESOURCES, MUST ALSO BE REPORTED AND MAY REQUIRE CONSIDERATION BY THE COI COMMITTEE. THE COI COMMITTEE RESERVES THE RIGHT TO MAKE FURTHER INQUIRIES INTO THE NATURE OF THE COVERED INDIVIDUAL'S REPORT SHOULD ADDITIONAL INFORMATION BE REQUIRED.
FORM 990, PART VI, SECTION B, LINE 12C (CONTINUED):	THE FOLLOWING FINANCIAL INTERESTS ARE EXEMPT FROM THESE REPORTING REQUIREMENTS: - SALARY, ROYALTIES OR OTHER REMUNERATION FROM THE COVERED INDIVIDUAL'S INSTITUTION; - INCOME FROM ACTIVITIES SPONSORED BY U.S. GOVERNMENTAL AGENCIES OR ENTITIES; - INCOME FOR SERVING AS SPECIAL REVIEWER OR ON A REVIEW PANEL FOR U.S. GOVERNMENTAL AGENCIES OR ENTITIES, OR A UNITED STATES INSTITUTION OF HIGHER EDUCATION, A UNITED STATES ACADEMIC TEACHING HOSPITAL, A MEDICAL CENTER, OR A RESEARCH INSTITUTE THAT IS AFFILIATED WITH A UNITED STATES INSTITUTION OF HIGHER EDUCATION. - TRAVEL EXPENSES PAID BY AN ENTITY LOCATED WITHIN THE U.S. AS PART OF A RESEARCH PROJECT (I.E. IF REIMBURSEMENT IS RECEIVED FROM A FOREIGN INSTITUTION OF HIGHER EDUCATION FOR WORK ON A RESEARCH PROJECT AT THE FOREIGN INSTITUTION, THOSE PAYMENTS ARE NOT EXEMPT FROM THE HHRI'S REPORTING REQUIREMENTS); - EQUITY INTEREST IN MUTUAL FUNDS, PENSION OR OTHER INSTITUTIONAL INVESTMENT FUNDS WHOSE INVESTMENT PRACTICES ARE BEYOND THE CONTROL OF THE INDIVIDUAL. FOR THE AVOIDANCE OF DOUBT, COVERED INDIVIDUALS MUST DISCLOSE ALL FOREIGN FINANCIAL INTERESTS (WHICH INCLUDES INCOME FROM SEMINARS, LECTURES, OR TEACHING ENGAGEMENTS, INCOME FROM SERVICE ON ADVISORY COMMITTEES OR REVIEW PANELS, AND REIMBURSED OR SPONSORED TRAVEL) RECEIVED FROM ANY FOREIGN ENTITY, INCLUDING FOREIGN INSTITUTIONS OF HIGHER EDUCATION OR FOREIGN GOVERNMENTS (WHICH INCLUDES LOCAL, PROVINCIAL, OR EQUIVALENT GOVERNMENTS OF ANOTHER COUNTRY). COVERED INDIVIDUALS WHO ARE TEMPORARILY ON A LEAVE OF ABSENCE, SABBATICAL OR REDUCED APPOINTMENT MUST ALSO REPORT THESE EXTERNAL RELATIONSHIPS. THE COI COMMITTEE WILL TAKE INTO CONSIDERATION THE COVERED INDIVIDUAL'S STATUS WHEN REVIEWING REPORTED INFORMATION. THE CONFLICT OF INTEREST COMMITTEE THE HHRI WILL MAINTAIN A CONFLICT OF INTEREST COMMITTEE TO DEAL WITH ISSUES CONCERNING THIS POLICY. THIS COMMITTEE SHALL BE CHAIRED BY THE HENNEPIN HEALTHCARE CHIEF COMPLIANCE OFFICER, AND SHALL HAVE THE FOLLOWING PRINCIPLE FUNCTIONS: - TO ASSIST IN THE IMPLEMENTATION OF THIS POLICY; - TO REVIEW DISCLOSURES OF CONFLICT OF INTEREST; - TO DEVELOP AND APPROVE ANY PLANS TO MANAGE, REDUCE OR ELIMINATE CONFLICTS; - TO RECOMMEND TO THE HHRI EXECUTIVE COMMITTEE ANY DISCIPLINARY ACTION TO BE TAKEN UNDER THIS POLICY; DISCIPLINARY ACTIONS TO BE APPROVED BY THE HHRI BOARD OF DIRECTORS; - UPON THE REQUEST OF AFFECTED PERSONNEL, TO REVIEW A DECISION BY AN ADMINISTRATION OFFICIAL THAT A DISCLOSED SITUATION CONSTITUTES AN ACTUAL CONFLICT OF INTEREST; - TO PERIODICALLY REVIEW THIS POLICY, INCLUDING THE SET FINANCIAL THRESHOLDS. THIS COMMITTEE SHALL BE COMPRISED OF THE FOLLOWING ORGANIZATIONAL OFFICERS: THE HHRI PRESIDENT, VICE PRESIDENT, SECRETARY/TREASURER, AND VICE PRESIDENT OF OPERATIONS/COO OF THE INSTITUTE, HENNEPIN HEALTHCARE'S CHIEF OF CLINICAL OPERATIONS, THE CHAIR (OR VICE CHAIR) OF THE INSTITUTIONAL REVIEW BOARD (IRB), THE CHAIR OF THE INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC) AND A COMMUNITY MEMBER TO BE APPOINTED BY THE PRESIDENT OF THE INSTITUTE. SHOULD THE COMMITTEE REQUIRE ADDITIONAL EXPERTISE, INCLUDING LEGAL COUNSEL, AD HOC MEMBERS MAY BE ASKED TO PARTICIPATE AS VOTING OR NON-VOTING MEMBERS. UNDER CERTAIN CIRCUMSTANCES, THE CHAIR OF THE CONFLICT OF INTEREST COMMITTEE MAY DETERMINE THAT AN EXECUTIVE-LEVEL REVIEW OF A CONFLICT OF INTEREST DISCLOSURE INVOLVING AT LEAST TWO MEMBERS OF THE FULL CONFLICT OF INTEREST COMMITTEE (I.E. THE CHAIR AND/OR THE VICE PRESIDENT OF OPERATIONS/COO OR ANOTHER MEMBER) IS APPROPRIATE. THIS EXECUTIVE REVIEW MAY BE USED WHEN ONE OR MORE OF THE FOLLOWING CRITERIA ARE MET: THE FINANCIAL DISCLOSURE IS < $5,000; THE DISCLOSURE INVOLVES AN ANTICIPATED CONFLICT; THE PROPOSED PROJECT INVOLVES MINIMAL RISK TO HUMANS; THE PROPOSED PROJECT REQUIRES MINIMAL INVOLVEMENT OF THE CONFLICTED PERSON; THE DISCLOSED CONFLICT INVOLVES MINIMAL RISK TO STUDY INTEGRITY (STUDY DESIGN, GENERATION OF DATA, ANALYSIS OF DATA, OR PRESENTATION OF RESULTS). DETAILS OF SUCH CONFLICTS AND ANY NECESSARY MITIGATION ADDRESSED VIA EXECUTIVE-LEVEL REVIEW WILL BE DOCUMENTED, AND A SUMMARY OF ANY ACTIONS TAKEN MADE AVAILABLE TO THE FULL CONFLICT OF INTEREST COMMITTEE. DETERMINING WHETHER A CONFLICT OF INTEREST REQUIRES MANAGEMENT OR ELIMINATION THE COI COMMITTEE'S CRITERIA FOR EVALUATING DISCLOSURES WILL INCLUDE BUT NOT BE LIMITED TO 1) RISKS TO RESEARCH SUBJECTS; 2) RISKS TO THE SCIENTIFIC INTEGRITY OF STUDY DESIGN, DATA COLLECTION, ANALYSIS AND REPORTING; AND 3) EXPECTED BENEFITS OF ACTIVITY. AN FCOI EXISTS WHEN THE INSTITUTION REASONABLY DETERMINES THAT A COVERED INDIVIDUAL'S SIGNIFICANT FINANCIAL INTEREST IS RELATED TO A PROJECT (I.E., THE SIGNIFICANT FINANCIAL INTEREST COULD BE AFFECTED BY THE RESEARCH OR IS THE SIGNIFICANT FINANCIAL INTEREST IN AN ENTITY WHOSE FINANCIAL INTEREST COULD BE AFFECTED BY THE RESEARCH) AND COULD DIRECTLY AND SIGNIFICANTLY AFFECT THE DESIGN, CONDUCT OR REPORTING OF THE RESEARCH. WHENEVER A COVERED INDIVIDUAL'S ACTIVITIES, RELATIONSHIPS, OR INTERESTS ARE UNDER REVIEW BY THE COI COMMITTEE, THE COVERED INDIVIDUAL WILL HAVE AN OPPORTUNITY TO PROVIDE INFORMATION TO THE COMMITTEE EITHER IN PERSON OR BY SUBMISSION OF A WRITTEN STATEMENT AND/OR THE PROVISION OF OTHER WRITTEN INFORMATION. MANAGING CONFLICT OF INTEREST WHEN THE COI COMMITTEE DETERMINES THAT A CONFLICT OF INTEREST EXISTS, THE COMMITTEE WILL EVALUATE THE CONFLICT SITUATION CONSIDERING FACTORS INCLUDING: THE NATURE OF THE ACTIVITY; THE NATURE OF THE FINANCIAL INTEREST; AND THE POTENTIAL FOR THE CONFLICT TO INFLUENCE THE ACTIVITY IN QUESTION. WHERE RESEARCH IS INVOLVED, THE COMMITTEE WILL EVALUATE THE RISK THE RESEARCH POSES TO RESEARCH SUBJECTS AND THE DEGREE TO WHICH THE OUTCOME OF THE RESEARCH MAY BE AFFECTED BY ANY FINANCIAL INTEREST. THE COMMITTEE WILL DETERMINE WHETHER THE CONFLICT SITUATION 1) CAN BE EFFECTIVELY MANAGED THROUGH DEVELOPMENT AND IMPLEMENTATION OF A CONFLICT MITIGATION PLAN; 2) CAN BE MANAGED BY CHANGING THE COVERED INDIVIDUAL'S TERMS OF PARTICIPATION IN AN INSTITUTIONAL ACTIVITY; OR 3) NEEDS TO BE ELIMINATED. POSSIBLE RECOMMENDATIONS INCLUDE APPROVAL OF THE ACTIVITY AS PROPOSED IF IT IS CONCLUDED THAT THE POTENTIAL FOR CONFLICT IS SO REMOTE OR INCONSEQUENTIAL THAT THERE IS MINIMAL PROBABILITY FOR BIASING THE OBJECTIVITY OF THE ACTIVITY. OTHER POSSIBLE RECOMMENDATIONS ARE TO REQUIRE PERIODIC PEER REVIEW OF THE ACTIVITY (OVERSIGHT) BY INDIVIDUALS INDEPENDENT OF THE EMPLOYEE, OUTSIDE MONITORS FOR THE ACTIVITY, DIVESTITURE OF THE FINANCIAL OR BUSINESS INTEREST, MODIFICATION OF THE PLAN OF WORK, OR ASSIGNMENT OF DIFFERENT EMPLOYEES WITHOUT A FINANCIAL OR BUSINESS INTEREST TO CONTROL THE ACTIVITY, OR LIMITING THE INDIVIDUAL'S ROLE AND RESPONSIBILITIES IN THE PROJECT. TO THE EXTENT POSSIBLE AND REASONABLE UNDER THE CIRCUMSTANCES, AND IN LIGHT OF THE IMPORTANCE OF THE ACTIVITY, THE REVIEW COMMITTEES AND RESPONSIBLE ADMINISTRATORS WILL WORK WITH EMPLOYEES TO DEVELOP MEANS FOR THE ACTIVITY TO TAKE PLACE WHILE PROTECTING THE INTEGRITY AND THE REPUTATION OF THE EMPLOYEES AND THE HHRI. EXAMPLES OF CONDITIONS OR RESTRICTIONS THAT MIGHT BE IMPOSED TO MANAGE A COVERED INDIVIDUAL'S FINANCIAL CONFLICT OF INTEREST INCLUDE, BUT ARE NOT LIMITED TO: - PUBLIC DISCLOSURE OF FINANCIAL CONFLICTS OF INTERESTS (E.G., WHEN PRESENTING OR PUBLISHING THE RESEARCH; TO STAFF MEMBERS WORKING ON THE PROJECT; TO THE INSTITUTION'S INSTITUTIONAL REVIEW BOARD(S), INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE(S), ETC; - FOR RESEARCH PROJECTS INVOLVING HUMAN SUBJECTS RESEARCH, DISCLOSURE OF FINANCIAL CONFLICTS OF INTEREST DIRECTLY TO PARTICIPANTS; - APPOINTMENT OF AN INDEPENDENT MONITOR CAPABLE OF TAKING MEASURES TO PROTECT THE DESIGN, CONDUCT, AND REPORTING OF THE RESEARCH AGAINST BIAS RESULTING FROM THE FINANCIAL CONFLICT OF INTEREST; - MODIFICATION OF THE RESEARCH PLAN; - CHANGE OF PERSONNEL OR PERSONNEL RESPONSIBILITIES, OR DISQUALIFICATIONS OF PERSONNEL FROM PARTICIPATION IN ALL OR A PORTION OF THE RESEARCH; - REDUCTION OR ELIMINATION OF THE FINANCIAL INTEREST (E.G., SALE OF AN EQUITY INTEREST); OR - SEVERANCE OF RELATIONSHIPS THAT CREATE FINANCIAL CONFLICTS IN ANY CASE IN WHICH THERE HAS BEEN A DETERMINATION THAT A PHS-FUNDED PROJECT OF CLINICAL RESEARCH WHOSE PURPOSE IS TO EVALUATE THE SAFETY OR EFFECTIVENESS OF A DRUG, MEDICAL DEVICE, OR TREATMENT HAS BEEN DESIGNED, CONDUCTED, OR REPORTED BY AN INVESTIGATOR WITH A FINANCIAL CONFLICT OF INTEREST THAT WAS NOT MANAGED OR REPORTED BY THE INSTITUTION AS REQUIRED BY FEDERAL REGULATION, THE INSTITUTION SHALL REQUIRE THE COVERED INDIVIDUAL INVOLVED TO DISCLOSE THE FINANCIAL CONFLICT OF INTEREST IN EACH PUBLIC PRESENTATION OF THE RESULTS OF THE RESEARCH AND TO REQUEST AN ADDENDUM TO PREVIOUSLY PUBLISHED PRESENTATIONS. IF THE COI COMMITTEE DETERMINES THAT A CONFLICT MITIGATION PLAN CAN EFFECTIVELY MANAGE THE CONFLICT SITUATION, THE COMMITTEE WILL WORK WITH THE COVERED INDIVIDUAL TO DEVELOP A CONFLICT MITIGATION PLAN THAT WILL:
FORM 990, PART VI, SECTION B, LINE 12C (CONTINUED):	- DESCRIBE THE CIRCUMSTANCES THAT GIVE RISE TO THE CONFLICT OF INTEREST UNDER INSTITUTIONAL POLICY; - SET FORTH SPECIFIC MANDATORY MITIGATION MECHANISMS; - SET FORTH A PLAN FOR MONITORING AND FOLLOW-UP; - ADDRESS ANY DISCLOSURES REQUIRED; - REQUIRE A WRITTEN CONFIRMATION OF CONSENT FROM THE COVERED INDIVIDUAL TO ALL REQUIREMENTS OF THE MANAGEMENT PLAN; - COMPLY WITH THE REQUIREMENTS OF ANY APPLICABLE SPONSOR REGULATIONS. WHEN PERSONNEL PARTICIPATE IN SPONSORED RESEARCH INVOLVING SUB-GRANTEES, CONTRACTORS OR COLLABORATORS OUTSIDE THE HHRI, REASONABLE STEPS WILL BE TAKEN TO ENSURE THAT INVESTIGATORS WORKING FOR THESE OUTSIDE ENTITIES COMPLY WITH APPROPRIATE CONFLICT OF INTEREST DISCLOSURE, REVIEW, AND MANAGEMENT REQUIREMENTS. THESE STEPS MAY INCLUDE REQUIRING THE INVESTIGATORS TO COMPLY WITH HHRI'S POLICY OR OBTAINING WRITTEN ASSURANCES FROM THE OUTSIDE ENTITY THAT IT COMPLIES WITH APPLICABLE FEDERAL REGULATIONS OR SPONSOR POLICIES ON CONFLICT OF INTEREST. THE OUTCOME OF THE COI COMMITTEE DELIBERATIONS AND ANY MITIGATION PLAN(S) WILL BE SHARED WITH THE COVERED INDIVIDUAL'S SUPERVISOR/DEPARTMENT HEAD. PUBLIC DISCLOSURE OF FCOIS COVERED INDIVIDUALS MUST DISCLOSE THEIR CONFLICTS OF INTEREST WHEN SUBMITTING RESEARCH REPORTS, REVIEWS, OPINION PIECES, AND LETTERS TO THE EDITOR OR OTHER TYPES OF COMMUNICATIONS FOR PUBLICATION. SUCH DISCLOSURES MUST BE MADE TO THE AUDIENCE FOR EDUCATIONAL PRESENTATIONS, AND TO THE RESPONSIBLE REPORTER OR EDITOR FOR NEWS ARTICLES, INTERVIEWS OR PRESS RELEASES. JOURNAL ARTICLES AND RESEARCH REPORTS MAY FOLLOW INDIVIDUAL JOURNAL OR FUNDING AGENCY REPORTING FORMATS. DISCLOSURE TO OTHER RESEARCH PERSONNEL WORKING ON A STUDY MAY ALSO BE REQUIRED BY THE COI COMMITTEE AS A PART OF ADDITIONAL PUBLIC DISCLOSURE REQUIREMENTS FOR CONFLICT MITIGATION. INSTITUTIONAL CONFLICT OF INTEREST INSTITUTIONS SUCH AS THE HHRI MAY HAVE FINANCIAL CONFLICTS OF INTEREST INDEPENDENT OF THOSE OF SPECIFIC INDIVIDUALS. EXAMPLES INCLUDE FUNDS ACCRUING TO THE INSTITUTION RATHER THAN TO AN INDIVIDUAL OR SPECIFIC LAB OR DEPARTMENT, INVESTMENTS, INTERESTS DERIVED FROM LICENSING, TECHNOLOGY TRANSFER OR PATENTS, OR SUPPORT OF INSTITUTIONAL EDUCATIONAL CONFERENCES. INSTITUTIONAL COI RAISES ISSUES SIMILAR TO THOSE RAISED BY INDIVIDUAL COI, AND SHOULD BE SUBJECT TO THE SAME SCRUTINY, DISCLOSURE AND MANAGEMENT PROCEDURES. EDUCATIONAL ACTIVITIES WHEN AN EDUCATIONAL ACTIVITY IS CONDUCTED BY HHRI AS THE SOLE ORGANIZER, THESE ACTIVITIES MAY NOT BE SUPPORTED BY FUNDS FROM VENDORS DOING BUSINESS WITH HHRI. WHEN EDUCATIONAL ACTIVITIES ARE CO-SPONSORED BY HHRI AND OTHER INSTITUTIONS (E.G. HENNEPIN HEALTH SYSTEM) WHICH DO NOT HAVE A SIMILAR PROHIBITION, THE CRITERIA OF THE ACCREDITATION COUNCIL FOR CONTINUING MEDICAL EDUCATION (ACCME) FOR COI IN CONTINUING MEDICAL EDUCATION MUST BE ADHERED TO BY ALL ORGANIZATIONS INVOLVED (SEE APPENDIX II). GIFTS THE HHRI MAY NOT ACCEPT GIFTS OR CONTRIBUTIONS FROM VENDORS WITH WHICH IT CONDUCTS BUSINESS OR WHEN THE DONOR HAS AN INTEREST IN THE RESEARCH BEING SUPPORTED, SUCH AS THE PURCHASING OF COMMON EQUIPMENT, ON AN INSTITUTIONAL LEVEL. THIS POLICY WOULD NOT APPLY TO VENDORS PROVIDING GOODS OR SERVICES TO INDIVIDUAL FACULTY OR STAFF OR LABORATORIES (IN WHICH HHRI AS AN INSTITUTION DOES NOT INFLUENCE THE CHOICE OF VENDOR OTHER THAN BY GUARANTEEING COMPETITIVE BIDDING WHEN REQUIRED) BUT WOULD APPLY TO VENDORS IN THE CASE THAT THE HHRI MAKES PURCHASING DECISIONS AS AN INSTITUTION, E.G., COMMON EQUIPMENT, BIOHAZARD DISPOSAL SERVICES. AN INSTITUTIONAL CONFLICT COMMITTEE CONSISTING OF THE HHRI CONFLICT OF INTEREST COMMITTEE PLUS A NON-HHS/HHRI EMPLOYED HHRI BOARD MEMBER WILL REVIEW ALL INSTITUTIONAL CONFLICTS OF INTEREST. THE HHRI COO WILL REPORT ALL INSTITUTIONAL FINANCIAL CONFLICTS OF ANY AMOUNT TO THE COMMITTEE FOR REVIEW.
FORM 990, PART VI, SECTION B, LINE 12C (CONTINUED):	THE HHRI CONFLICT OF INTEREST POLICY, EFFECTIVE MAY 1, 2024, IS DESIGNED TO UPHOLD THE INTEGRITY OF RESEARCH AND EDUCATION BY ENSURING TRANSPARENCY AND INDEPENDENCE FROM FINANCIAL INFLUENCES. IT APPLIES TO ALL INDIVIDUALS AFFILIATED WITH HHRIINCLUDING EMPLOYEES, RESEARCHERS, BOARD MEMBERS, AND THEIR IMMEDIATE FAMILIESAND MANDATES THE DISCLOSURE OF ALL EXTERNAL FINANCIAL RELATIONSHIPS, REGARDLESS OF SIZE. THESE DISCLOSURES ARE REVIEWED BY A CONFLICT OF INTEREST COMMITTEE, WHICH MAY IMPLEMENT MITIGATION PLANS TO MANAGE OR ELIMINATE POTENTIAL CONFLICTS. THE POLICY PROHIBITS ACCEPTING GIFTS FROM VENDORS, GHOSTWRITING, AND ENDORSEMENTS TIED TO INSTITUTIONAL ROLES, AND REQUIRES REGULAR TRAINING AND STRICT COMPLIANCE. VIOLATIONS CAN RESULT IN DISCIPLINARY ACTION, INCLUDING RETRAINING, SUSPENSION, OR TERMINATION, AND ARE REPORTED TO RELEVANT FEDERAL AGENCIES WHEN NECESSARY. THIS POLICY REFLECTS HHRI'S BROADER COMMITMENT TO ETHICAL CONDUCT, SCIENTIFIC INTEGRITY, AND PUBLIC TRUST. IT ENSURES THAT BOTH INDIVIDUAL AND INSTITUTIONAL INTERESTS ARE ALIGNED WITH THE MISSION TO DELIVER UNBIASED, HIGH-QUALITY RESEARCH AND CARE.
FORM 990, PART IX, LINE 11G	PURCHASED SERVICES: PROGRAM SERVICE EXPENSES 1,887,689. MANAGEMENT AND GENERAL EXPENSES 184,814. FUNDRAISING EXPENSES 0. TOTAL EXPENSES 2,072,503. SUBCONTRACT PAYMENTS: PROGRAM SERVICE EXPENSES 19,404,035. MANAGEMENT AND GENERAL EXPENSES 0. FUNDRAISING EXPENSES 0. TOTAL EXPENSES 19,404,035.

For Paperwork Reduction Act Notice, see the Instructions for Form 990 or 990-EZ.

Cat. No. 51056K

Schedule O (Form 990) (Rev. 1-2025)

Additional Data

Software ID:
Software Version:

- TIN:

SCHEDULE R
(Form 990)
(Rev. January 2025)

Department of the Treasury
Internal Revenue Service

Related Organizations and Unrelated Partnerships

Complete if the organization answered "Yes" on Form 990, Part IV, line 33, 34, 35b, 36, or 37.
Attach to Form 990.
Go to www.irs.gov/Form990 for instructions and the latest information.

OMB No. 1545-0047

Open to Public Inspection

Name of the organization

HENNEPIN HEALTHCARE RESEARCH INSTITUTE

Employer identification number

41-1677920

Part I

Identification of Disregarded Entities. Complete if the organization answered "Yes" on Form 990, Part IV, line 33.

(a) Name, address, and EIN (if applicable) of disregarded entity	(b) Primary activity	(c) Legal domicile (state or foreign country)	(d) Total income	(e) End-of-year assets	(f) Direct controlling entity

Part II

Identification of Related Tax-Exempt Organizations. Complete if the organization answered "Yes" on Form 990, Part IV, line 34 because it had one or more related tax-exempt organizations during the tax year.

(a) Name, address, and EIN of related organization	(b) Primary activity	(c) Legal domicile (state or foreign country)	(d) Exempt Code section	(e) Public charity status (if section 501(c)(3))	(f) Direct controlling entity	(g) Section 512(b)(13) controlled entity?
(a) Name, address, and EIN of related organization	(b) Primary activity	(c) Legal domicile (state or foreign country)	(d) Exempt Code section	(e) Public charity status (if section 501(c)(3))	(f) Direct controlling entity	Yes	No
(1)HENNEPIN HEALTHCARE SYSTEM INC 701 PARK AVENUE MINNEAPOLIS,MN55415 42-1707837	HOSPITAL	MN	501(C)(3)	LINE 3	N/A		No
(2)HENNEPIN HEALTH FOUNDATION 701 PARK AVENUE MINNEAPOLIS,MN55415 41-0845733	PHILANTHROPIC SUPPORT	MN	501(C)(3)	LINE 7	HENNEPIN HEALTHCARE SYSTEM INC		No
(3)HENNEPIN COUNTY 300 SOUTH 6TH STREET MINNEAPOLIS,MN55487 41-6005801	GOVERNMENTAL UNIT	MN			N/A		No

For Paperwork Reduction Act Notice, see the Instructions for Form 990.

Cat. No. 50135Y

Schedule R (Form 990) (Rev. 1-2025)

Page 2

Part III

Identification of Related Organizations Taxable as a Partnership. Complete if the organization answered "Yes" on Form 990, Part IV, line 34, because it had one or more related organizations treated as a partnership during the tax year.

(a) Name, address, and EIN of related organization	(b) Primary activity	(c) Legal domicile (state or foreign country)	(d) Direct controlling entity	(f) Share of total income	(g) Share of end-of-year assets	(h) Disproprtionate allocations?		(i) Code V-UBI amount in box 20 of Schedule K-1 (Form 1065)	(j) General or managing partner?		(k) Percentage ownership
(a) Name, address, and EIN of related organization	(b) Primary activity	(c) Legal domicile (state or foreign country)	(d) Direct controlling entity	(f) Share of total income	(g) Share of end-of-year assets	Yes	No	(i) Code V-UBI amount in box 20 of Schedule K-1 (Form 1065)	Yes	No	(k) Percentage ownership

Part IV

Identification of Related Organizations Taxable as a Corporation or Trust. Complete if the organization answered "Yes" on Form 990, Part IV, line 34 because it had one or more related organizations treated as a corporation or trust during the tax year.

(a) Name, address, and EIN of related organization	(b) Primary activity	(c) Legal domicile (state or foreign country)	(d) Direct controlling entity	(e) Type of entity (C corp, S corp, or trust)	(f) Share of total income	(g) Share of end-of-year assets	(h) Percentage ownership	(i) Section 512(b)(13) controlled entity?
(a) Name, address, and EIN of related organization	(b) Primary activity	(c) Legal domicile (state or foreign country)	(d) Direct controlling entity	(e) Type of entity (C corp, S corp, or trust)	(f) Share of total income	(g) Share of end-of-year assets	(h) Percentage ownership	Yes	No

Schedule R (Form 990) (Rev. 1-2025)

Page 3

Part V

Transactions With Related Organizations. Complete if the organization answered "Yes" on Form 990, Part IV, line 34, 35b, or 36.

Note. Complete line 1 if any entity is listed in Parts II, III, or IV of this schedule.

Yes

1 During the tax year, did the orgranization engage in any of the following transactions with one or more related organizations listed in Parts II-IV?

a Receipt of (i) interest, (ii) annuities, (iii) royalties, or (iv) rent from a controlled entity .....................

b Gift, grant, or capital contribution to related organization(s) ............................

c Gift, grant, or capital contribution from related organization(s) ............................

Yes

d Loans or loan guarantees to or for related organization(s) ............................

e Loans or loan guarantees by related organization(s) ............................

f Dividends from related organization(s) ............................

g Sale of assets to related organization(s) ............................

h Purchase of assets from related organization(s) ............................

i Exchange of assets with related organization(s) ............................

j Lease of facilities, equipment, or other assets to related organization(s) .......................

Yes

k Lease of facilities, equipment, or other assets from related organization(s) ......................

Yes

l Performance of services or membership or fundraising solicitations for related organization(s) .....................

m Performance of services or membership or fundraising solicitations by related organization(s) .................

Yes

n Sharing of facilities, equipment, mailing lists, or other assets with related organization(s) ...................

Yes

o Sharing of paid employees with related organization(s) ............................

Yes

p Reimbursement paid to related organization(s) for expenses ............................

Yes

q Reimbursement paid by related organization(s) for expenses ............................

Yes

r Other transfer of cash or property to related organization(s) ............................

s Other transfer of cash or property from related organization(s) ............................

If the answer to any of the above is "Yes," see the instructions for information on who must complete this line, including covered relationships and transaction thresholds.

(a) Name of related organization	(b) Transaction type (a-s)	(c) Amount involved	(d) Method of determining amount involved

Schedule R (Form 990) (Rev. 1-2025)

Page 4

Part VI

Unrelated Organizations Taxable as a Partnership. Complete if the organization answered "Yes" on Form 990, Part IV, line 37.

Provide the following information for each entity taxed as a partnership through which the organization conducted more than five percent of its activities (measured by total assets or gross revenue) that was not a related organization. See instructions regarding exclusion for certain investment partnerships.

(a) Name, address, and EIN of entity	(b) Primary activity	(c) Legal domicile (state or foreign country)	(e) Are all partners section 501(c)(3) organizations?		(f) Share of total income	(g) Share of end-of-year assets	(h) Disproprtionate allocations?		(i) Code V-UBI amount in box 20 of Schedule K-1 (Form 1065)	(j) General or managing partner?		(k) Percentage ownership
(a) Name, address, and EIN of entity	(b) Primary activity	(c) Legal domicile (state or foreign country)	Yes	No	(f) Share of total income	(g) Share of end-of-year assets	Yes	No	(i) Code V-UBI amount in box 20 of Schedule K-1 (Form 1065)	Yes	No	(k) Percentage ownership

Schedule R (Form 990) (Rev. 1-2025)

Page 5

Part VII

Supplemental Information

Provide additional information for responses to questions on Schedule R. See instructions.

Return Reference	Explanation

Schedule R (Form 990) (Rev. 1-2025)

Additional Data

Software ID:
Software Version:

		Prior Year	Current Year
8	Contributions and grants (Part VIII, line 1h) .........	55,200,822	52,551,531
9	Program service revenue (Part VIII, line 2g) .........	0	0
10	Investment income (Part VIII, column (A), lines 3, 4, and 7d ) ....	1,899,286	2,165,690
11	Other revenue (Part VIII, column (A), lines 5, 6d, 8c, 9c, 10c, and 11e)	0	0
12	Total revenue—add lines 8 through 11 (must equal Part VIII, column (A), line 12)	57,100,108	54,717,221
13	Grants and similar amounts paid (Part IX, column (A), lines 1–3 )...	0	0
14	Benefits paid to or for members (Part IX, column (A), line 4).....	0	0
15	Salaries, other compensation, employee benefits (Part IX, column (A), lines 5–10)	23,288,550	26,129,366
16a	Professional fundraising fees (Part IX, column (A), line 11e) .....	0	0
b	Total fundraising expenses (Part IX, column (D), line 25) 0
17	Other expenses (Part IX, column (A), lines 11a–11d, 11f–24e)....	32,122,044	27,375,037
18	Total expenses. Add lines 13–17 (must equal Part IX, column (A), line 25)	55,410,594	53,504,403
19	Revenue less expenses. Subtract line 18 from line 12.......	1,689,514	1,212,818
		Beginning of Current Year	End of Year
20	Total assets (Part X, line 16).............	72,662,924	75,518,149
21	Total liabilities (Part X, line 26).............	12,527,529	10,600,602
22	Net assets or fund balances. Subtract line 21 from line 20.....	60,135,395	64,917,547

Sign Here

	Signature of officer	Date

	Type or print name and title


4a	(Code: ) (Expenses $ 44,198,511 including grants of $ 0 ) (Revenue $ 0 )
	CLINICAL RESEARCH AND EDUCATIONAL ACTIVITIES:HENNEPIN HEALTHCARE RESEARCH INSTITUTE (HHRI) INVESTIGATORS ARE PRACTICING PHYSICIANS, SCIENTISTS AND OTHER MEDICAL PROFESSIONALS USING THEIR EXPERTISE TO ADVANCE MEDICAL KNOWLEDGE AND IMPROVE THE CARE PATIENTS RECEIVE. HHRI'S RESEARCH SUBJECTS ARE DIVERSE WITH A FOCUS ON ACUTE CARE/TRAUMA, ADDICTION, HEALTH SERVICES, AND INFECTIOUS DISEASES. PARTICIPANTS IN HHRI CLINICAL RESEARCH STUDIES (INCLUDING TRAUMATIC BRAIN INJURY, SUBSTANCE USE DISORDERS, DEMENTIA, CHRONIC DISEASES, AND HIV/AIDS) HAVE ACCESS TO SOME OF THE LATEST MEDICAL TREATMENTS AVAILABLE TODAY. IN ADDITION TO PURSUING INNOVATIVE NEW THERAPIES, OUR INVESTIGATORS ARE TRAINING THE NEXT GENERATION OF SCIENTISTS AND MEDICAL PROFESSIONALS, INSPIRING THEM TO CARRY OUT HHRI'S MISSION OF IMPROVING PATIENT CARE AND THE HEALTH OF OUR COMMUNITY THROUGH RESEARCH AND EDUCATION. OUR INVESTIGATORS ALSO PUBLISH REGULARLY IN PEER-REVIEWED JOURNALSSEE SCHEDULE O - GENERAL STATEMENT.

4b	(Code: ) (Expenses $ 5,131,984 including grants of $ 0 ) (Revenue $ 0 )
	PRE-CLINICAL AND LABORATORY RESEARCH:IN THE HHRI LABS, WE STUDY THE CAUSES AND TREATMENTS OF DISEASE. OUR RESEARCH SUBJECTS ARE DIVERSE WITH A FOCUS ON ACUTE CARE/TRAUMA, ADDICTION, HEALTH SERVICES, AND INFECTIOUS DISEASES. AT HHRI, WE DEVELOP INNOVATIVE NEW TREATMENTS TO SOLVE SOME OF OUR COMMUNITY'S MOST-CHALLENGING HEALTH PROBLEMS. RESEARCHERS IN OUR LABS ARE MDS, MD/PHDS, PHDS, PHARMDS, AND OTHER MEDICAL AND SCIENCE PROFESSIONALS WORKING TO ADVANCE MEDICAL KNOWLEDGE AND IMPROVE THE CARE PATIENTS RECEIVE. OUR INVESTIGATORS ALSO PUBLISH REGULARLY IN PEER-REVIEWED JOURNALS SEE SCHEDULE O - GENERAL STATEMENT.

4c	(Code: ) (Expenses $ including grants of $ ) (Revenue $ )












4d	Other program services (Describe in Schedule O.)
	(Expenses $ including grants of $ ) (Revenue $ )
4e	Total program service expenses49,330,495

(A) Name and title	(B) Average hours per week (list any hours for related organizations below dotted line)				(D) Reportable compensation from the organization (W-2/1099-MISC/1099-NEC)	(E) Reportable compensation from related organizations (W-2/1099-MISC/1099-NEC)	(F) Estimated amount of other compensation from the organization and related organizations
(A) Name and title
(18) KIM MILLER........................................................................ VP OF OPERATIONS & COO	40.00 .......................0.00	X			177,092	0	38,973
(19) DAVID GILBERTSON........................................................................ PROGRAM CO-DIRECTOR	40.00 .......................0.00		X		260,228	0	54,866
(20) RACHEL NYGAARD........................................................................ DIRECTOR/SURGERY RESEARCH	40.00 .......................0.00		X		231,903	0	55,144
(21) JIANNOUNG LIU........................................................................ DIRECTOR, ANALYSIS	40.00 .......................0.00		X		213,572	0	46,142
(22) JON SNYDER........................................................................ DIRECTOR, TRANSPLANT EPIDEMIOLOGY	40.00 .......................0.00		X		213,084	0	44,043
(23) SHULING LI........................................................................ EPIDDEMIOLOGIST & BIOSTATISTICIAN	40.00 .......................0.00		X		174,782	0	37,706
(24) JASON BAKER MD........................................................................ FORMER VICE PRESIDENT/INVESTIGATOR	28.80 .......................10.20			X	0	294,166	56,368
(25) AJAY ISRANI MD MS........................................................................ FORMER PRESIDENT/INVESTIGATOR	21.20 .......................18.80			X	0	266,063	45,030
(26) ANNE MURRAY MD MS........................................................................ FORMER SECRETARY/TREASURER/INVESTIGATOR	32.10 .......................5.90			X	0	218,197	41,525

1b	Sub-Total..............
c	Total from continuation sheets to Part VII, Section A..
d	Total (add lines 1b and 1c).........	1,387,761	4,091,192	876,210

1	Briefly describe the organization’s mission or most significant activities: IMPROVE PATIENT CARE AND THE HEALTH OF OUR COMMUNITY THROUGH RESEARCH AND EDUCATION.
2	Check this box
3	Number of voting members of the governing body (Part VI, line 1a) ........	3	14
4	Number of independent voting members of the governing body (Part VI, line 1b) .....	4	7
5	Total number of individuals employed in calendar year 2024 (Part V, line 2a) ......	5	266
6	Total number of volunteers (estimate if necessary) .............	6	202
7a	Total unrelated business revenue from Part VIII, column (C), line 12 ........	7a	0
b	Net unrelated business taxable income from Form 990-T, Part I, line 11 .........	7b	0

1a	Federated campaigns..		1a
b	Membership dues..		1b
c	Fundraising events..		1c
d	Related organizations		1d	3,904,315
e	Government grants (contributions)		1e	32,150,854

f	All other contributions, gifts, grants, and similar amounts not included above		1f	16,496,362

g	Noncash contributions included in lines 1a - 1f:$		1g

h Total. Add lines 1a-1f.......		52,551,531

		Business Code
2a
b
c
d
e
f	All other program service revenue.
g	Total. Add lines 2a–2f .....

3 Investment income (including dividends, interest, and othersimilar amounts) ......			2,173,495			2,173,495
4 Income from investment of tax-exempt bond proceeds
5 Royalties...........
			(i) Real	(ii) Personal
6a	Gross rents	6a
b	Less: rental expenses	6b
c	Rental income or (loss)	6c
d	Net rental income or (loss).......
			(i) Securities	(ii) Other
7a	Gross amount from sales of assets other than inventory	7a
b	Less: cost or other basis and sales expenses	7b		7,805
c	Gain or (loss)	7c		-7,805
d	Net gain or (loss).........			-7,805			-7,805
8a	Gross income from fundraising events (not including $ of contributions reported on line 1c). See Part IV, line 18 ....
			8a
b	Less: direct expenses ...		8b
c	Net income or (loss) from fundraising events..
9a	Gross income from gaming activities. See Part IV, line 19 ...
			9a
b	Less: direct expenses ...		9b
c	Net income or (loss) from gaming activities..
10a	Gross sales of inventory, less returns and allowances ..
			10a
b	Less: cost of goods sold ..		10b
c	Net income or (loss) from sales of inventory..

Business Code
11a
b
c
d	All other revenue ....
e	Total. Add lines 11a–11d ......
12	Total revenue. See instructions.....			54,717,221	0	0	2,165,690

1	Grants and other assistance to domestic organizations and domestic governments. See Part IV, line 21 ....
2	Grants and other assistance to domestic individuals. See Part IV, line 22 ...........
3	Grants and other assistance to foreign organizations, foreign governments, and foreign individuals. See Part IV, lines 15 and 16. .............
4	Benefits paid to or for members .......
5	Compensation of current officers, directors, trustees, and key employees ...........	400,684	261,449	139,235
6	Compensation not included above, to disqualified persons (as defined under section 4958(f)(1)) and persons described in section 4958(c)(3)(B) .........
7	Other salaries and wages........	19,862,905	17,667,077	2,195,828
8	Pension plan accruals and contributions (include section 401(k) and 403(b) employer contributions) ....	1,416,022	1,285,362	130,660
9	Other employee benefits .......	3,218,047	2,762,790	455,257
10	Payroll taxes ...........	1,231,708	1,111,909	119,799
11	Fees for services (non-employees):
a	Management ......
b	Legal .........	67,935	61,320	6,615
c	Accounting ...........	55,678		55,678
d	Lobbying ...........	1,000	1,000
e	Professional fundraising services. See Part IV, line 17
f	Investment management fees ......
g	Other (If line 11g amount exceeds 10% of line 25, column (A) amount, list line 11g expenses on Schedule O)	21,476,538	21,291,724	184,814
12	Advertising and promotion ....
13	Office expenses .......	2,730,738	2,404,248	326,490
14	Information technology ......	105,000		105,000
15	Royalties ..
16	Occupancy ...........	1,182,024	1,004,534	177,490
17	Travel ............	541,443	537,694	3,749
18	Payments of travel or entertainment expenses for any federal, state, or local public officials .
19	Conferences, conventions, and meetings ....	61,544	61,297	247
20	Interest ...........
21	Payments to affiliates .......
22	Depreciation, depletion, and amortization ..	493,867	386,006	107,861
23	Insurance ...	122,691		122,691
24	Other expenses. Itemize expenses not covered above (List miscellaneous expenses in line 24e. If line 24e amount exceeds 10% of line 25, column (A) amount, list line 24e expenses on Schedule O.)
a	SUBJECT EXPENSES	216,876	216,051	825
b	DEVELOPMENT AND TRAININ	124,075	118,885	5,190
c	DUES AND SUBSCRIPTIONS	90,273	61,406	28,867
d	MISCELLANEOUS EXPENSE	58,143	51,818	6,325
e	All other expenses	47,212	45,925	1,287
25	Total functional expenses. Add lines 1 through 24e	53,504,403	49,330,495	4,173,908	0
26	Joint costs. Complete this line only if the organization reported in column (B) joint costs from a combined educational campaign and fundraising solicitation. Check here if following SOP 98-2 (ASC 958-720).

1	Cash–non-interest-bearing ........			4,680,554	1	4,458,736
2	Savings and temporary cash investments .........			72,649	2	76,120
3	Pledges and grants receivable, net ......			14,566,562	3	11,450,225
4	Accounts receivable, net .............				4
5	Loans and other receivables from any current or former officer, director, trustee, key employee, creator or founder, substantial contributor, or 35% controlled entity or family member of any of these persons .......
					5
6	Loans and other receivables from other disqualified persons (as defined under section 4958(f)(1)), and persons described in section 4958(c)(3)(B) ...
					6
7	Notes and loans receivable, net ...........				7
8	Inventories for sale or use ............				8
9	Prepaid expenses and deferred charges ......			407,146	9	556,434
10a	Land, buildings, and equipment: cost or other basis. Complete Part VI of Schedule D	10a	13,278,532
b	Less: accumulated depreciation	10b	11,823,222	1,800,036	10c	1,455,310
11	Investments—publicly traded securities .			49,721,299	11	55,460,656
12	Investments—other securities. See Part IV, line 11 .....				12
13	Investments—program-related. See Part IV, line 11 ..				13
14	Intangible assets ...............				14
15	Other assets. See Part IV, line 11 ...........			1,414,678	15	2,060,668
16	Total assets. Add lines 1 through 15 (must equal line 33)...			72,662,924	16	75,518,149

17	Accounts payable and accrued expenses .....	10,903,428	17	8,324,491
18	Grants payable ...		18
19	Deferred revenue .........	479,271	19	369,708
20	Tax-exempt bond liabilities .........		20
21	Escrow or custodial account liability. Complete Part IV of Schedule D		21
22	Loans and other payables to any current or former officer, director, trustee, key employee, creator or founder, substantial contributor, or 35% controlled entity or family member of any of these persons .........
			22
23	Secured mortgages and notes payable to unrelated third parties ..		23
24	Unsecured notes and loans payable to unrelated third parties ..		24
25	Other liabilities (including federal income tax, payables to related third parties, and other liabilities not included on lines 17 - 24). Complete Part X of Schedule D	1,144,830	25	1,906,403
26	Total liabilities. Add lines 17 through 25..	12,527,529	26	10,600,602

	Organizations that follow FASB ASC 958, check here and complete lines 27, 28, 32, and 33.
27	Net assets without donor restrictions ..........	32,928,106	27	34,736,810
28	Net assets with donor restrictions ...........	27,207,289	28	30,180,737
	Organizations that do not follow FASB ASC 958, check here and complete lines 29 through 33.
29	Capital stock or trust principal, or current funds .....		29
30	Paid-in or capital surplus, or land, building or equipment fund ...		30
31	Retained earnings, endowment, accumulated income, or other funds		31
32	Total net assets or fund balances ...........	60,135,395	32	64,917,547
33	Total liabilities and net assets/fund balances ........	72,662,924	33	75,518,149

1	Was the organization a U.S. transferor of property to a foreign corporation during the tax year? If "Yes," the organization may be required to file Form 926, Return by a U.S. Transferor of Property to a Foreign Corporation (see Instructions for Form 926). . . . . . . . . . . . . . . . . . . . . . . . . . . . . .	Yes	No
2	Did the organization have an interest in a foreign trust during the tax year? If "Yes," the organization may be required to separately file Form 3520, Annual Return to Report Transactions with Foreign Trusts and Receipt of Certain Foreign Gifts, and/or Form 3520-A, Annual Information Return of Foreign Trust With a U.S. Owner (see Instructions for Forms 3520 and 3520-A; don't file with Form 990). . . . . . . . . . . . . . . . . . . . . . . .	Yes	No
3	Did the organization have an ownership interest in a foreign corporation during the tax year? If "Yes," the organization may be required to file Form 5471, Information Return of U.S. Persons with Respect to Certain Foreign Corporations. (see Instructions for Form 5471). . . . . . . . . . . . . . . . . . . . . . . . . . . .	Yes	No
4	Was the organization a direct or indirect shareholder of a passive foreign investment company or a qualified electing fund during the tax year? If “Yes,” the organization may be required to file Form 8621, Information Return by a Shareholder of a Passive Foreign Investment Company or Qualified Electing Fund. (see Instructions for Form 8621) .	Yes	No
5	Did the organization have an ownership interest in a foreign partnership during the tax year? If "Yes," the organization may be required to file Form 8865, Return of U.S. Persons with Respect to Certain Foreign Partnerships (see Instructions for Form 8865). . . . . . . . . . . . . . . . . . . . . . . . . . . . . .	Yes	No
6	Did the organization have any operations in or related to any boycotting countries during the tax year? If "Yes," the organization may be required to separately file Form 5713, International Boycott Report (see Instructions for Form 5713; don't file with Form 990).. . . . . . . . . . . . . . . . . . . . . . . . . . . .	Yes	No