TY 2025 Form 990

(A) Name and title	(B) Average hours per week (list any hours for related organizations below dotted line)	(C) Position (do not check more than one box, unless person is both an officer and a director/trustee)	(E) Reportable compensation from related organizations (W-2/1099-MISC/1099-NEC)
(1) PHILIP WEISBERG...................................................................... CHAIR	5.00 .................	X	X			0	0
(2) PHILIP R PELLER...................................................................... AUDIT COMMITTEE CHAIR	2.00 .................	X				0	0
(3) BERNADETTE MARIANI...................................................................... NOMINATING COMMITTEE CHAIR	2.00 .................	X				0	0
(4) WILLIAM M DRUMMY JR...................................................................... DEVELOPMENT COMMITTEE CHAIR	2.00 .................	X				0	0
(5) SAUD A SADIQ MD...................................................................... DIRECTOR/CHIEF RESEARCH SCIENTIST	15.00 .................	X	X			0	0
(6) LEE J SEIDLER...................................................................... CHAIRMAN EMERITUS	0.50 .................				X	0	0
(7) AMANDA B OPPENHEIMER...................................................................... CHIEF OPERATING OFFICER	40.00 .................		X			177,186	14,734
(8) CLIFFORD EISLER...................................................................... TREASURER	2.00 .................	X	X			0	0
(9) SHARYL REISMAN...................................................................... SECRETARY	2.00 .................	X	X			0	0
(10) TALENE KELLY...................................................................... DIRECTOR OF DEVELOPMENT	40.00 .................			X		145,206	5,589
(11) JAMES CONNELL...................................................................... DIRECTOR	0.50 .................	X				0	0
(12) MANNY SCHNAIDMAN...................................................................... DIRECTOR	0.50 .................	X				0	0
(13) ALAN TISCH...................................................................... DIRECTOR	0.50 .................	X				0	0
(14) THOMAS R MAYER...................................................................... DIRECTOR	0.50 .................	X				0	0
(15) MUSA MAYER...................................................................... DIRECTOR	0.50 .................	X				0	0
(16) PAUL PURCELL...................................................................... DIRECTOR	0.50 .................	X				0	0
(17) PHILIP J PURCELL...................................................................... DIRECTOR	0.50 .................	X				0	0

(A) Name and title	(B) Average hours per week (list any hours for related organizations below dotted line)	(C) Position (do not check more than one box, unless person is both an officer and a director/trustee)
(18) ALLA WEISBERG........................................................................ DIRECTOR	0.50 .......................	X		0	0
(19) DANIEL TISCH........................................................................ DIRECTOR	0.50 .......................	X		0	0
(20) BONNIE TISCH........................................................................ DIRECTOR	0.50 .......................	X		0	0
(21) RICHARD SCHWARTZ........................................................................ DIRECTOR	0.50 .......................	X		0	0
(22) GRETA RUBIN SCHWARTZ........................................................................ DIRECTOR	0.50 .......................	X		0	0
(23) MONIKA PAREKH........................................................................ DIRECTOR	0.50 .......................	X		0	0
(24) DEVEN PAREKH........................................................................ DIRECTOR	0.50 .......................	X		0	0
(25) ELIZABETH MASLOW MONTESANO........................................................................ DIRECTOR	0.50 .......................	X		0	0
(26) JAMES MARIANI........................................................................ DIRECTOR	0.50 .......................	X		0	0
(27) PAUL LATTANZIO........................................................................ DIRECTOR	0.50 .......................	X		0	0
(28) CHARLES THOELE........................................................................ DIRECTOR	0.50 .......................	X		0	0
(29) BRADLEY H FRIEDRICH........................................................................ DIRECTOR	0.50 .......................	X		0	0
(30) BONNIE EISLER........................................................................ DIRECTOR	0.50 .......................	X		0	0
(31) CYNTHIA D BRODSKY........................................................................ DIRECTOR	0.50 .......................	X		0	0
(32) ENKE BASHLLARI PHD........................................................................ DIRECTOR	0.50 .......................	X		0	0
(33) HILLARY MANDEL........................................................................ DIRECTOR	0.50 .......................	X		0	0
(34) VIOLAINE HARRIS........................................................................ SENIOR RESEARCH SCIENTIST	40.00 .......................		X	255,540	16,563
(35) JERRY LIN........................................................................ SENIOR STAFF ASSOCIATE	40.00 .......................		X	135,882	10,951
(36) JAMIE WONG........................................................................ RESEARCH SCIENTIST	40.00 .......................		X	148,790	11,887

(A) Name and business address	(B) Description of services	(C) Compensation
CONROY CONSTRUCTION INC 135 E WASHINGTON AVE PEARL RIVER,NY10965	GENERAL CONTRACTOR	582,444
MISPRO BIOTECH SERVICES CORP 11-2901 RACHEL STREET EAST MONTREAL,QUEBECH1W 4A4 CA	VIVARIUM OPERATIONS	167,873
CIPRIANI 110 EAST 42ND S NEW YORK,NY10017	VENUE	161,650
WHITE WINGS CONSULTING LLC 110 WEST 34TH STREET SUITE 1106 NEW YORK,NY10001	INFORMATION TECHNOLOGY	113,366

2 Total number of independent contractors (including but not limited to those listed above) who received more than $100,000 of compensation from the organization 4

- TIN:

SCHEDULE A
(Form 990)

Department of the Treasury
Internal Revenue Service

Public Charity Status and Public Support

Complete if the organization is a section 501(c)(3) organization or a section 4947(a)(1) nonexempt charitable trust.
Attach to Form 990 or Form 990-EZ.
Go to www.irs.gov/Form990 for instructions and the latest information.

OMB No. 1545-0047

2025

Open to Public
Inspection

Name of the organization

TISCH MULTIPLE SCLEROSIS RESEARCH CENTER
OF NEW YORK INC

Employer identification number

25-1922851

Part I

Reason for Public Charity Status (All organizations must complete this part.) See instructions.

The organization is not a private foundation because it is: (For lines 1 through 12, check only one box.)

A church, convention of churches, or association of churches described in section 170(b)(1)(A)(i).

A school described in section 170(b)(1)(A)(ii). (Attach Schedule E (Form 990).)

A hospital or a cooperative hospital service organization described in section 170(b)(1)(A)(iii).

A medical research organization operated in conjunction with a hospital described in section 170(b)(1)(A)(iii). Enter the hospital's name, city, and state:

An organization operated for the benefit of a college or university owned or operated by a governmental unit described in section 170(b)(1)(A)(iv). (Complete Part II.)

A federal, state, or local government or governmental unit described in section 170(b)(1)(A)(v).

An organization that normally receives a substantial part of its support from a governmental unit or from the general public described in section 170(b)(1)(A)(vi). (Complete Part II.)

A community trust described in section 170(b)(1)(A)(vi). (Complete Part II.)

An agricultural research organization described in 170(b)(1)(A)(ix) operated in conjunction with a land-grant college or university or a non-land grant college of agriculture. See instructions. Enter the name, city, and state of the college or university:

An organization that normally receives: (1) more than 33 1/3% of its support from contributions, membership fees, and gross receipts from activities related to its exempt functions—subject to certain exceptions, and (2) no more than 33 1/3% of its support from gross investment income and unrelated business taxable income (less section 511 tax) from businesses acquired by the organization after June 30, 1975. See section 509(a)(2). (Complete Part III.)

An organization organized and operated exclusively to test for public safety. See section 509(a)(4).

An organization organized and operated exclusively for the benefit of, to perform the functions of, or to carry out the purposes of one or more publicly supported organizations described in section 509(a)(1) or section 509(a)(2). See section 509(a)(3). Check the box on lines 12a through 12d that describes the type of supporting organization and complete lines 12e, 12f, and 12g.

Type I. A supporting organization operated, supervised, or controlled by its supported organization(s), typically by giving the supported organization(s) the power to regularly appoint or elect a majority of the directors or trustees of the supporting organization. You must complete Part IV, Sections A and B.

Type II. A supporting organization supervised or controlled in connection with its supported organization(s), by having control or management of the supporting organization vested in the same persons that control or manage the supported organization(s). You must complete Part IV, Sections A and C.

Type III functionally integrated. A supporting organization operated in connection with, and functionally integrated with, its supported organization(s) (see instructions). You must complete Part IV, Sections A, D, and E.

Type III non-functionally integrated. A supporting organization operated in connection with its supported organization(s) that is not functionally integrated. The organization must generally satisfy a distribution requirement and an attentiveness requirement (see instructions). You must complete Part IV, Sections A and D, and Part V.

Check this box if the organization received a written determination from the IRS that it is a Type I, Type II, Type III functionally integrated, or Type III non-functionally integrated supporting organization.

Enter the number of supported organizations ...........................

Provide the following information about the supported organization(s).

(i) Name of supported organization	(ii) EIN	(iv) Is the organization listed in your governing document?		(v) Amount of monetary support (see instructions)	(vi) Amount of other support (see instructions)
(i) Name of supported organization	(ii) EIN	Yes	No	(v) Amount of monetary support (see instructions)	(vi) Amount of other support (see instructions)


Total

For Paperwork Reduction Act Notice, see the Instructions for
Form 990 or 990-EZ.

Cat. No. 11285F

Schedule A (Form 990) 2025

Page 2

Part II

Support Schedule for Organizations Described in Sections 170(b)(1)(A)(iv) and 170(b)(1)(A)(vi)
(Complete only if you checked the box on line 5, 7, or 8 of Part I or if the organization failed to qualify under Part III. If the organization failed to qualify under the tests listed below, please complete Part III.)

Section A. Public Support

Calendar year (or fiscal year beginning in)		(a) 2021	(b) 2022	(c) 2023	(d) 2024	(e) 2025	(f) Total
1	Gifts, grants, contributions, and membership fees received. (Do not include any "unusual grant.") ..
2	Tax revenues levied for the organization's benefit and either paid to or expended on its behalf ....
3	The value of services or facilities furnished by a governmental unit to the organization without charge..
4	Total. Add lines 1 through 3
5	The portion of total contributions by each person (other than a governmental unit or publicly supported organization) included on line 1 that exceeds 2% of the amount shown on line 11, column (f) ..
6	Public support. Subtract line 5 from line 4.

Section B. Total Support

Calendar year (or fiscal year beginning in)		(a) 2021	(b) 2022	(c) 2023	(d) 2024	(e) 2025	(f) Total
7	Amounts from line 4..
8	Gross income from interest, dividends, payments received on securities loans, rents, royalties and income from similar sources...
9	Net income from unrelated business activities, whether or not the business is regularly carried on..
10	Other income. Do not include gain or loss from the sale of capital assets (Explain in Part VI.)..
11	Total support. Add lines 7 through 10

Gross receipts from related activities, etc. (see instructions) ..................

First 5 years. If the Form 990 is for the organization's first, second, third, fourth, or fifth tax year as a section 501(c)(3) organization, check this box and stop here ........................................

Section C. Computation of Public Support Percentage

Public support percentage for 2025 (line 6, column (f) divided by line 11, column (f)) .........

Public support percentage for 2024 Schedule A, Part II, line 14 ...............

16a

33 1/3% support test—2025. If the organization did not check the box on line 13, and line 14 is 33 1/3% or more, check this box
and stop here. The organization qualifies as a publicly supported organization .......................

33 1/3% support test—2024. If the organization did not check a box on line 13 or 16a, and line 15 is 33 1/3% or more, check this
box and stop here. The organization qualifies as a publicly supported organization .....................

17a

10%-facts-and-circumstances test—2025. If the organization did not check a box on line 13, 16a, or 16b, and line 14 is 10% or more, and if the organization meets the "facts-and-circumstances" test, check this box and stop here. Explain in Part VI how the organization meets the "facts-and-circumstances" test. The organization qualifies as a publicly supported organization ............

10%-facts-and-circumstances test—2024. If the organization did not check a box on line 13, 16a, 16b, or 17a, and line 15 is 10% or more, and if the organization meets the "facts-and-circumstances" test, check this box and stop here. Explain in Part VI how the organization meets the "facts-and-circumstances" test. The organization qualifies as a publicly supported organization ............

Private foundation. If the organization did not check a box on line 13, 16a, 16b, 17a, or 17b, check this box and see
instructions .....................................................

Schedule A (Form 990) 2025

Page 3

Part III

Support Schedule for Organizations Described in Section 509(a)(2)
(Complete only if you checked the box on line 10 of Part I or if the organization failed to qualify under Part II. If the organization fails to qualify under the tests listed below, please complete Part II.)

Section A. Public Support

Calendar year (or fiscal year beginning in)		(a) 2021	(b) 2022	(c) 2023	(d) 2024	(e) 2025	(f) Total
1	Gifts, grants, contributions, and membership fees received. (Do not include any "unusual grants.")	8,963,171	6,839,857	6,778,214	5,576,393	5,829,026	33,986,661
2	Gross receipts from admissions, merchandise sold or services performed, or facilities furnished in any activity that is related to the organization's tax-exempt purpose	2,768,420	3,613,926	4,139,547	4,812,248	3,689,699	19,023,840
3	Gross receipts from activities that are not an unrelated trade or business under section 513 .....
4	Tax revenues levied for the organization's benefit and either paid to or expended on its behalf...	0	0	0	0	0
5	The value of services or facilities furnished by a governmental unit to the organization without charge	-4,875	-14,871	-1,895	-8,044	-7,006	-36,691
6	Total. Add lines 1 through 5	11,726,716	10,438,912	10,915,866	10,380,597	9,511,719	52,973,810
7a	Amounts included on lines 1, 2, and 3 received from disqualified persons						0
b	Amounts included on lines 2 and 3 received from other than disqualified persons that exceed the greater of $5,000 or 1% of the amount on line 13 for the year.						0
c	Add lines 7a and 7b..						0
8	Public support. (Subtract line 7c from line 6.)						52,973,810

Section B. Total Support

Calendar year (or fiscal year beginning in)		(a) 2021	(b) 2022	(c) 2023	(d) 2024	(e) 2025	(f) Total
9	Amounts from line 6	11,726,716	10,438,912	10,915,866	10,380,597	9,511,719	52,973,810
10a	Gross income from interest, dividends, payments received on securities loans, rents, royalties and income from similar sources	1,227	5,924	32,253	7,994	226	47,624
b	Unrelated business taxable income (less section 511 taxes) from businesses acquired after June 30, 1975
c	Add lines 10a and 10b	1,227	5,924	32,253	7,994	226	47,624
11	Net income from unrelated business activities not included on line 10b, whether or not the business is regularly carried on.	0	0	0	0	0
12	Other income. Do not include gain or loss from the sale of capital assets (Explain in Part VI.) ..
13	Total support. (Add lines 9, 10c, 11, and 12.)..	11,727,943	10,444,836	10,948,119	10,388,591	9,511,945	53,021,434

Section C. Computation of Public Support Percentage

Public support percentage for 2025 (line 8, column (f) divided by line 13, column (f)) .........

99.910 %

Public support percentage from 2024 Schedule A, Part III, line 15 ...............

99.910 %

Section D. Computation of Investment Income Percentage

Investment income percentage for 2025 (line 10c, column (f) divided by line 13, column (f)) ......

0.090 %

Investment income percentage from 2024 Schedule A, Part III, line 17 .............

0.090 %

19a

33 1/3% support tests-2025. If the organization did not check the box on line 14, and line 15 is more than 33 1/3%, and line 17 is not more than 33 1/3%, check this box and stop here. The organization qualifies as a publicly supported organization .......

33 1/3 % support tests—2024. If the organization did not check a box on line 14 or line 19a, and line 16 is more than 33 1/3% and line 18 is not more than 33 1/3%, check this box and stop here. The organization qualifies as a publicly supported organization .....

Private foundation. If the organization did not check a box on line 14, 19a, or 19b, check this box and see instructions ....

Schedule A (Form 990) 2025

Page 4

Part IV

Supporting Organizations

(Complete only if you checked a box on line 12 of Part I. If you checked box 12a, of Part I, complete Sections A and B. If you checked box 12b, of Part I, complete Sections A and C. If you checked box 12c, of Part I, complete Sections A, D, and E. If you checked box12d, of Part I, complete Sections A and D, and complete Part V.)

Section A. All Supporting Organizations

Yes

Are all of the organization’s supported organizations listed by name in the organization’s governing documents?
If "No," describe in Part VI how the supported organizations are designated. If designated by class or purpose,
describe the designation. If historic and continuing relationship, explain.

Did the organization have any supported organization that does not have an IRS determination of status under section 509(a)(1) or (2)? If "Yes," explain in Part VI how the organization determined that the supported organization was described in section 509(a)(1) or (2).

Did the organization have a supported organization described in section 501(c)(4), (5), or (6)? If "Yes," answer lines 3b and 3c below.

Did the organization confirm that each supported organization qualified under section 501(c)(4), (5), or (6) and satisfied the public support tests under section 509(a)(2)? If "Yes," describe in Part VI when and how the organization made the determination.

Did the organization ensure that all support to such organizations was used exclusively for section 170(c)(2)(B) purposes? If "Yes," explain in Part VI what controls the organization put in place to ensure such use.

Was any supported organization not organized in the United States ("foreign supported organization")? If “Yes” and if you checked box 12a or 12b in Part I, answer lines 4b and 4c below.

Did the organization have ultimate control and discretion in deciding whether to make grants to the foreign supported organization? If “Yes,” describe in Part VI how the organization had such control and discretion despite being controlled or supervised by or in connection with its supported organizations.

Did the organization support any foreign supported organization that does not have an IRS determination under sections 501(c)(3) and 509(a)(1) or (2)? If “Yes,” explain in Part VI what controls the organization used to ensure that all support to the foreign supported organization was used exclusively for section 170(c)(2)(B) purposes.

Did the organization add, substitute, or remove any supported organizations during the tax year? If “Yes,” answer lines 5b and 5c below (if applicable). Also, provide detail in Part VI, including (i) the names and EIN numbers of the supported organizations added, substituted, or removed; (ii) the reasons for each such action; (iii) the authority under the organization's organizing document authorizing such action; and (iv) how the action was accomplished (such as by amendment to the organizing document).

Type I or Type II only. Was any added or substituted supported organization part of a class already designated in the organization's organizing document?

Substitutions only. Was the substitution the result of an event beyond the organization's control?

Did the organization provide support (whether in the form of grants or the provision of services or facilities) to anyone other than (i) its supported organizations, (ii) individuals that are part of the charitable class benefited by one or more of its supported organizations, or (iii) other supporting organizations that also support or benefit one or more of the filing organization’s supported organizations? If “Yes,” provide detail in Part VI.

Did the organization provide a grant, loan, compensation, or other similar payment to a substantial contributor (defined in section 4958(c)(3)(C)), a family member of a substantial contributor, or a 35% controlled entity with regard to a substantial contributor? If “Yes,” complete Part I of Schedule L (Form 990) .

Did the organization make a loan to a disqualified person (as defined in section 4958) not described on line 7? If “Yes,” complete Part I of Schedule L (Form 990).

Was the organization controlled directly or indirectly at any time during the tax year by one or more disqualified persons, as defined in section 4946 (other than foundation managers and organizations described in section 509(a)(1) or (2))? If “Yes,” provide detail in Part VI.

Did one or more disqualified persons (as defined on line 9a) hold a controlling interest in any entity in which the supporting organization had an interest? If “Yes,” provide detail in Part VI.

Did a disqualified person (as defined on line 9a) have an ownership interest in, or derive any personal benefit from, assets in which the supporting organization also had an interest? If “Yes,” provide detail in Part VI.

10a

Was the organization subject to the excess business holdings rules of section 4943 because of section 4943(f) (regarding certain Type II supporting organizations, and all Type III non-functionally integrated supporting organizations)? If “Yes,” answer line 10b below.

10a

Did the organization have any excess business holdings in the tax year? (Use Schedule C, Form 4720, to determine whether the organization had excess business holdings).

10b

Schedule A (Form 990) 2025

Page 5

Part IV

Supporting Organizations (continued)

Yes

Has the organization accepted a gift or contribution from any of the following persons?

A person who directly or indirectly controls, either alone or together with persons described on lines 11b and 11c below, the governing body of a supported organization?

11a

A family member of a person described on 11a above?

11b

A 35% controlled entity of a person described on line 11a or 11b above? If “Yes” to 11a, 11b, or 11c, provide detail in Part VI.

11c

Section B. Type I Supporting Organizations

Yes

Did the officers, directors, trustees, or membership of one or more supported organizations have the power to regularly appoint or elect at least a majority of the organization’s directors or trustees at all times during the tax year? If “No,” describe in Part VI how the supported organization(s) effectively operated, supervised, or controlled the organization’s activities. If the organization had more than one supported organization, describe how the powers to appoint and/or remove directors or trustees were allocated among the supported organizations and what conditions or restrictions, if any, applied to such powers during the tax year.

Did the organization operate for the benefit of any supported organization other than the supported organization(s) that operated, supervised, or controlled the supporting organization? If “Yes,” explain in Part VI how providing such benefit carried out the purposes of the supported organization(s) that operated, supervised or controlled the supporting organization.

Section C. Type II Supporting Organizations

Yes

Were a majority of the organization’s directors or trustees during the tax year also a majority of the directors or trustees of each of the organization’s supported organization(s)? If “No,” describe in Part VI how control or management of the supporting organization was vested in the same persons that controlled or managed the supported organization(s).

Section D. All Type III Supporting Organizations

Yes

Did the organization provide to each of its supported organizations, by the last day of the fifth month of the organization’s tax year, (i) a written notice describing the type and amount of support provided during the prior tax year, (ii) a copy of the Form 990 that was most recently filed as of the date of notification, and (iii) copies of the organization’s governing documents in effect on the date of notification, to the extent not previously provided?

Were any of the organization’s officers, directors, or trustees either (i) appointed or elected by the supported organization(s) or (ii) serving on the governing body of a supported organization? If "No," explain in Part VI how the organization maintained a close and continuous working relationship with the supported organization(s).

By reason of the relationship described in line 2 above, did the organization’s supported organizations have a significant voice in the organization’s investment policies and in directing the use of the organization’s income or assets at all times during the tax year? If "Yes," describe in Part VI the role the organization’s supported organizations played in this regard.

Section E. Type III Functionally-Integrated Supporting Organizations

Check the box next to the method that the organization used to satisfy the Integral Part Test during the year (see instructions):

The organization satisfied the Activities Test. Complete line 2 below.

The organization is the parent of each of its supported organizations. Complete line 3 below.

The organization supported a governmental supported organization. Describe in Part VI how you supported a governmental supported organization (see instructions).

Activities Test. Answer lines 2a and 2b below.

Yes

Did substantially all of the organization’s activities during the tax year directly further the exempt purposes of its supported organization(s)? If "Yes," then in Part VI identify those supported organizations and explain how these activities directly furthered their exempt purposes, how the organization was responsive to each of its supported organizations, and how the organization determined that these activities constituted substantially all of its activities.

Did the activities described on line 2a, above, constitute activities that, but for the organization’s involvement, one or more of the organization’s supported organization(s) would have been engaged in? If “Yes,” explain in Part VI the reasons for the organization’s position that its supported organization(s) would have engaged in these activities but for the organization’s involvement.

Parent of Supported Organizations. Answer lines 3a, 3b, and 3c below.

Are the organization and its supported organization(s) part of an integrated system (for example, a hospital system)? If “Yes,” provide details in Part VI.

Did the organization direct the policies, programs, and activities of each of its supported organizations? If "Yes," describe in Part VI the role played by the organization in this regard.

Did the organization have the power to regularly appoint or elect (and remove) a majority of the officers, directors, or trustees of each of the supported organizations?If "Yes" or "No", provide details in Part VI.

Schedule A (Form 990) 2025

Page 6

Part V

Type III Non-Functionally Integrated 509(a)(3) Supporting Organizations

Check here if the organization satisfied the Integral Part Test as a qualifying trust on Nov. 20, 1970 (explain in Part VI). See instructions. All other Type III non-functionally integrated supporting organizations must complete Sections A through E.

	Section A - Adjusted Net Income		(A) Prior Year	(B) Current Year (optional)
1	Net short-term capital gain	1
2	Recoveries of prior-year distributions	2
3	Other gross income (see instructions)	3
4	Add lines 1 through 3	4
5	Depreciation and depletion	5
6	Portion of operating expenses paid or incurred for production or collection of gross income or for management, conservation, or maintenance of property held for production of income (see instructions)	6
7	Other expenses (see instructions)	7
8	Adjusted Net Income (subtract lines 5, 6 and 7 from line 4)	8

	Section B - Minimum Asset Amount		(A) Prior Year	(B) Current Year (optional)
1	Aggregate fair market value of all non-exempt-use assets (see instructions for short tax year or assets held for part of year):	1
a	Average monthly value of securities	1a
b	Average monthly cash balances	1b
c	Fair market value of other non-exempt-use assets	1c
d	Total (add lines 1a, 1b, and 1c)	1d
e	Discount claimed for blockage or other factors (explain in detail in Part VI):
2	Acquisition indebtedness applicable to non-exempt use assets	2
3	Subtract line 2 from line 1d	3
4	Cash deemed held for exempt use. Enter 0.015 of line 3 (for greater amount, see instructions).	4
5	Net value of non-exempt-use assets (subtract line 4 from line 3)	5
6	Multiply line 5 by 0.035	6
7	Recoveries of prior-year distributions	7
8	Minimum Asset Amount (add line 7 to line 6)	8

	Section C - Distributable Amount		Current Year
1	Adjusted net income for prior year (from Section A, line 8, Column A)	1
2	Enter 85% of line 1	2
3	Minimum asset amount for prior year (from Section B, line 8, Column A)	3
4	Enter greater of line 2 or line 3	4
5	Income tax imposed in prior year	5
6	Distributable Amount. Subtract line 5 from line 4, unless subject to emergency temporary reduction (see instructions)	6

Check here if the current year is the organization's first as a non-functionally- integrated Type III supporting organization (see instructions)

Schedule A (Form 990) 2025

Page 7

Part V

Type III Non-Functionally Integrated 509(a)(3) Supporting Organizations(continued)

Section D - Distributions		Current Year
1 Amounts paid to supported organizations to accomplish exempt purposes	1
2 Amounts paid to perform activity that directly furthers exempt purposes of supported organizations, in excess of income from activity	2
3 Administrative expenses paid to accomplish exempt purposes of supported organizations	3
4 Amounts paid to acquire exempt-use assets	4
5 Qualified set-aside amounts (prior IRS approval required - provide details in Part VI)	5
6Total annual distributions. Add lines 1 through 5.	6
7 Distributions to attentive supported organizations to which the organization is responsive (provide details in Part VI). See instructions	7
8 Distributable amount for 2025 from Section C, line 6	8
9 Line 7 amount divided by Line 8 amount	9

Section E - Distribution Allocations (see instructions)		(i) Excess Distributions	(ii) Underdistributions Pre-2025	(iii) Distributable Amount for 2025
1 Distributable amount for 2025 from Section C, line 6
2 Underdistributions, if any, for years prior to 2025 (reasonable cause required-- explain in Part VI). See instructions.
3 Excess distributions carryover, if any, to 2025:
a From 2020.......
b From 2021.......
c From 2022.......
d From 2023.......
e From 2024.......
fTotal of lines 3a through e
g Applied to underdistributions of prior years
h Applied to 2025 distributable amount
i Carryover from 2020 not applied (see instructions)
j Remainder. Subtract lines 3g, 3h, and 3i from line 3f.
4Distributions for 2025 from Section D, line 6:
$
a Applied to underdistributions of prior years
b Applied to 2025 distributable amount
c Remainder. Subtract lines 4a and 4b from line 4.
5 Remaining underdistributions for years prior to 2025, if any. Subtract lines 3g and 4a from line 2. If the amount is greater than zero, explain in Part VI. See instructions.
6 Remaining underdistributions for 2025. Subtract lines 3h and 4b from line 1. If the amount is greater than zero, explain in Part VI. See instructions.
7 Excess distributions carryover to 2026. Add lines 3j and 4c.
8 Breakdown of line 7:
a Excess from 2021.....
b Excess from 2022.....
c Excess from 2023.....
d Excess from 2024.....
e Excess from 2025.....

Schedule A (Form 990) (2025)

Schedule A (Form 990) 2025

Page 8

Part VI

Supplemental Information. Provide the explanations required by Part II, line 10; Part II, line 17a or 17b; Part III, line 12; Part IV, Section A, lines 1, 2, 3b, 3c, 4b, 4c, 5a, 6, 9a, 9b, 9c, 11a, 11b, and 11c; Part IV, Section B, lines 1 and 2; Part IV, Section C, line 1; Part IV, Section D, lines 2 and 3; Part IV, Section E, lines 1c, 2a, 2b, 3a, 3b, and 3c; Part V, line 1; Part V, Section B, line 1e; Part V Section D, lines 5 and 7; and Part V, Section E, lines 2, 5, and 6. Also complete this part for any additional information. (See instructions).

Facts And Circumstances Test

Return Reference	Explanation

Schedule A (Form 990) 2025

Additional Data

Software ID:
Software Version:

- TIN:

Schedule B
(Form 990)
(Rev. January 2025)

Department of the Treasury
Internal Revenue Service

Schedule of Contributors

Attach to Form 990, 990-EZ, or 990-PF.

Go to www.irs.gov/Form990 for the latest information.

OMB No. 1545-0047

Name of the organization

TISCH MULTIPLE SCLEROSIS RESEARCH CENTER
OF NEW YORK INC

Employer identification number

25-1922851

Organization type (check one):

Filers of:

Section:

Form 990 or 990-EZ

501(c)( ) (enter number) organization

4947(a)(1) nonexempt charitable trust not treated as a private foundation

527 political organization

Form 990-PF

501(c)(3) exempt private foundation

4947(a)(1) nonexempt charitable trust treated as a private foundation

501(c)(3) taxable private foundation

Check if your organization is covered by the General Rule or a Special Rule.
Note: Only a section 501(c)(7), (8), or (10) organization can check boxes for both the General Rule and a Special Rule. See instructions.

General Rule

For an organization filing Form 990, 990-EZ, or 990-PF that received, during the year, contributions totaling $5,000 or more (in money or other property) from any one contributor. Complete Parts I and II. See instructions for determining a contributor's total contributions.

Special Rules

For an organization described in section 501(c)(3) filing Form 990 or 990-EZ that met the 33¹/3% support test of the regulations
under sections 509(a)(1) and 170(b)(1)(A)(vi), that checked Schedule A (Form 990 or 990-EZ), Part II, line 13, 16a, or 16b, and that received from any one contributor, during the year, total contributions of the greater of (1) $5,000 or (2) 2% of the amount on (i) Form 990, Part VIII, line 1h, or (ii) Form 990-EZ, line 1. Complete Parts I and II.

For an organization described in section 501(c)(7), (8), or (10) filing Form 990 or 990-EZ that received from any one contributor,
during the year, total contributions of more than $1,000 exclusively for religious, charitable, scientific, literary, or educational purposes, or for the prevention of cruelty to children or animals. Complete Parts I, II, and III.

For an organization described in section 501(c)(7), (8), or (10) filing Form 990 or 990-EZ that received from any one contributor,
during the year, contributions exclusively for religious, charitable, etc., purposes, but no such contributions totaled more than $1,000. If this box is checked, enter here the total contributions that were received during the year for an exclusively religious, charitable, etc., purpose. Don't complete any of the parts unless the General Rule applies to this organization because it received nonexclusively religious, charitable, etc., contributions totaling $5,000 or more during the year ......... $

Caution: An organization that isn't covered by the General Rule and/or the Special Rules doesn't file Schedule B (Form 990,
990-EZ, or 990-PF), but it must answer “No” on Part IV, line 2, of its Form 990; or check the box on line H of its Form 990-EZ
or on its Form 990PF, Part I, line 2, to certify that it doesn't meet the filing requirements of Schedule B (Form 990,
990-EZ, or 990-PF).

For Paperwork Reduction Act Notice, see the Instructions
for Form 990, 990-EZ, or 990-PF.

Cat. No. 30613XSchedule B (Form 990) (Rev. 1-2025)

Schedule B (Form 990) (Rev. 2025) Page 2

Name of organization TISCH MULTIPLE SCLEROSIS RESEARCH CENTER OF NEW YORK INC

Part I	Contributors (see instructions). Use duplicate copies of Part I if additional space is needed.
(a) No.	(b) Name, address, and ZIP + 4	(c) Total contributions	(d) Type of contribution
RESTRICTED	,	$ RESTRICTED	Person Payroll Noncash (Complete Part II for noncash contributions.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Total contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II for noncash contributions.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Total contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II for noncash contributions.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Total contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II for noncash contributions.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Total contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II for noncash contributions.)
(a) No.	(b) Name, address, and ZIP + 4	(c) Total contributions	(d) Type of contribution
		$	Person Payroll Noncash (Complete Part II for noncash contributions.)
Schedule B (Form 990) (Rev. 1-2025)

Schedule B (Form 990) (Rev. 1-2025)

Page 3

Name of organization TISCH MULTIPLE SCLEROSIS RESEARCH CENTER OF NEW YORK INC		Employer identification number 25-1922851

Part II	Noncash Property (see instructions). Use duplicate copies of Part II if additional space is needed.
(a) No. from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (See instructions)	(d) Date received
		$
(a) No. from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (See instructions)	(d) Date received
		$
(a) No. from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (See instructions)	(d) Date received
		$
(a) No. from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (See instructions)	(d) Date received
		$
(a) No. from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (See instructions)	(d) Date received
		$
(a) No. from Part I	(b) Description of noncash property given	(c) FMV (or estimate) (See instructions)	(d) Date received
		$
Schedule B (Form 990) (Rev. 1-2025)

Schedule B (Form 990) (Rev. 1-2025)

Page 4


Name of organization TISCH MULTIPLE SCLEROSIS RESEARCH CENTER OF NEW YORK INC			Employer identification number 25-1922851
Part III Exclusively religious, charitable, etc., contributions to organizations described in section 501(c) (7), (8), or (10) that total more than $1,000 for the year from any one contributor. Complete columns (a) through (e) and the following line entry. For organizations completing Part III, enter the total of exclusively religious, charitable, etc., contributions of $1,000 or less for the year. (Enter this information once. See instructions.) $ Use duplicate copies of Part III if additional space is needed.

(a)
No. from Part I

(b) Purpose of gift

(d) Description of how gift is held

(e) Transfer of gift
Transferee's name, address, and ZIP 4	Relationship of transferor to transferee

(a)
No. from Part I

(b) Purpose of gift

(d) Description of how gift is held

(e) Transfer of gift
Transferee's name, address, and ZIP 4	Relationship of transferor to transferee

(a)
No. from Part I

(b) Purpose of gift

(d) Description of how gift is held

(e) Transfer of gift
Transferee's name, address, and ZIP 4	Relationship of transferor to transferee

(a)
No. from Part I

(b) Purpose of gift

(d) Description of how gift is held

(e) Transfer of gift
Transferee's name, address, and ZIP 4	Relationship of transferor to transferee

Schedule B (Form 990) (Rev. 1-2025)

Additional Data

Software ID:
Software Version:

- TIN:

SCHEDULE D
(Form 990)

Department of the Treasury
Internal Revenue Service

Supplemental Financial Statements

Complete if the organization answered "Yes," on Form 990,
Part IV, line 6, 7, 8, 9, 10, 11a, 11b, 11c, 11d, 11e, 11f, 12a, or 12b.
Attach to Form 990.
Go to www.irs.gov/Form990 for instructions and the latest information.

OMB No. 1545-0047

Open to Public Inspection

Name of the organization

TISCH MULTIPLE SCLEROSIS RESEARCH CENTER
OF NEW YORK INC

Employer identification number

25-1922851

Part I

Organizations Maintaining Donor Advised Funds or Other Similar Funds or Accounts. Complete if the organization answered "Yes" on Form 990, Part IV, line 6.

		(a) Donor advised funds	(b) Funds and other accounts
1	Total number at end of year .........
2	Aggregate value of contributions to (during year)
3	Aggregate value of grants from (during year)
4	Aggregate value at end of year ........

Did the organization inform all donors and donor advisors in writing that the assets held in donor advised funds are the organization’s property, subject to the organization’s exclusive legal control? ............

Yes No

Did the organization inform all grantees, donors, and donor advisors in writing that grant funds can be used only for charitable purposes and not for the benefit of the donor or donor advisor, or for any other purpose conferring impermissible private benefit? ...................................

Yes No

Part II

Conservation Easements.
Complete if the organization answered "Yes" on Form 990, Part IV, line 7.

Purpose(s) of conservation easements held by the organization (check all that apply).

Preservation of land for public use (e.g., recreation or education) Preservation of an historically important land area

Protection of natural habitat Preservation of a certified historic structure

Preservation of open space

Complete lines 2a through 2d if the organization held a qualified conservation contribution in the form of a conservation easement on the last day of the tax year.


a	Total number of conservation easements ......................	2a
b	Total acreage restricted by conservation easements ....................	2b
c	Number of conservation easements on a certified historic structure included in (a) .....	2c
d	Number of conservation easements included in (c) acquired after July 25, 2006, and not on a historic structure listed in the National Register ...	2d

Number of conservation easements modified, transferred, released, extinguished, or terminated by the organization during the
tax year

Number of states where property subject to conservation easement is located

Does the organization have a written policy regarding the periodic monitoring, inspection, handling of violations, and enforcement of the conservation easements it holds? ............

Yes No

Staff and volunteer hours devoted to monitoring, inspecting, handling of violations, and enforcing conservation easements during the year

Amount of expenses incurred in monitoring, inspecting, handling of violations, and enforcing conservation easements during the year
$

Does each conservation easement reported on line 2(d) above satisfy the requirements of section 170(h)(4)(B)(i) and section 170(h)(4)(B)(ii)? .............................

Yes No

In Part XIII, describe how the organization reports conservation easements in its revenue and expense statement, and
balance sheet, and include, if applicable, the text of the footnote to the organization’s financial statements that describes
the organization’s accounting for conservation easements.

Part III

Organizations Maintaining Collections of Art, Historical Treasures, or Other Similar Assets.
Complete if the organization answered "Yes" on Form 990, Part IV, line 8.

If the organization elected, as permitted under FASB ASC 958, not to report in its revenue statement and balance sheet works of art, historical treasures, or other similar assets held for public exhibition, education, or research in furtherance of public service, provide, in Part XIII, the text of the footnote to its financial statements that describes these items.

If the organization elected, as permitted under FASB ASC 958, to report in its revenue statement and balance sheet works of art, historical treasures, or other similar assets held for public exhibition, education, or research in furtherance of public service, provide the following amounts relating to these items:

(i)

Revenue included on Form 990, Part VIII, line 1 ......................... $

(ii)

Assets included in Form 990, Part X ............................... $

If the organization received or held works of art, historical treasures, or other similar assets for financial gain, provide the
following amounts required to be reported under FASB ASC 958 relating to these items:

Revenue included on Form 990, Part VIII, line 1 .......................... $

Assets included in Form 990, Part X ............................... $

For Paperwork Reduction Act Notice, see the Instructions for Form 990.

Cat. No. 52283D

Schedule D (Form 990) (Rev. 1-2025)

Page 2

Part III

Organizations Maintaining Collections of Art, Historical Treasures, or Other Similar Assets (continued)

Using the organization’s acquisition, accession, and other records, check any of the following that are a significant use of its collection items (check all that apply):

Public exhibition

Loan or exchange programs

Scholarly research

Other

Preservation for future generations

Provide a description of the organization’s collections and explain how they further the organization’s exempt purpose in
Part XIII.

During the year, did the organization solicit or receive donations of art, historical treasures or other similar
assets to be sold to raise funds rather than to be maintained as part of the organization’s collection?...

Yes No

Part IV

Escrow and Custodial Arrangements. Complete if the organization answered "Yes" on Form 990, Part IV, line 9, or reported an amount on Form 990, Part X, line 21.

Is the organization an agent, trustee, custodian or other intermediary for contributions or other assets not
included on Form 990, Part X? ....................................

Yes No


b	If "Yes," explain the arrangement in Part XIII and complete the following table:		Amount
c	Beginning balance .............................	1c
d	Additions during the year ............................	1d
e	Distributions during the year ..........................	1e
f	Ending balance ................................	1f

Did the organization include an amount on Form 990, Part X, line 21, for escrow or custodial account liability? ...

Yes No

If "Yes," explain the arrangement in Part XIII. Check here if the explanation has been provided in Part XIII ....

Part V

Endowment Funds.
Complete if the organization answered "Yes" on Form 990, Part IV, line 10.

		(a) Current year	(b) Prior year	(c) Two years back	(d) Three years back	(e) Four years back

1a	Beginning of year balance ....
b	Contributions ...
c	Net investment earnings, gains, and losses
d	Grants or scholarships ...
e	Other expenditures for facilities and programs ...
f	Administrative expenses ....
g	End of year balance ......

Provide the estimated percentage of the current year end balance (line 1g, column (a)) held as:

Board designated or quasi-endowment

Permanent endowment

Term endowment

The percentages on lines 2a, 2b, and 2c should equal 100%.

Are there endowment funds not in the possession of the organization that are held and administered for the
organization by:

Yes

(i) Unrelated organizations .................

3a(i)

(ii) Related organizations .................

3a(ii)

If "Yes" on 3a(ii), are the related organizations listed as required on Schedule R? .........

Describe in Part XIII the intended uses of the organization's endowment funds.

Part VI

Land, Buildings, and Equipment.
Complete if the organization answered "Yes" on Form 990, Part IV, line 11a. See Form 990, Part X, line 10.

Description of property		(a) Cost or other basis (investment)	(b) Cost or other basis (other)	(c) Accumulated depreciation	(d) Book value

1a	Land .....
b	Buildings ....
c	Leasehold improvements	18,504,106	8,591,268	9,912,838
d	Equipment ....	6,955,091	4,320,061	2,635,030
e	Other .....	994,048	815,255	178,793
Total. Add lines 1a through 1e. (Column (d) must equal Form 990, Part X, column (B), line 10(c).)..				12,726,661

Schedule D (Form 990) (Rev. 1-2025)

Page 3

Part VII

Investments - Other Securities.
Complete if the organization answered "Yes" on Form 990, Part IV, line 11b. See Form 990, Part X, line 12.

(a) Description of security or category (including name of security)	(b) Book value	(c) Method of valuation: Cost or end-of-year market value
(1) Financial derivatives.........
(2) Closely-held equity interests........
(3)Other
(A)
(B)
(C)
(D)
(E)
(F)
(G)
(H)
Total. (Column (b) must equal Form 990, Part X, col. (B) line 12.)

Part VIII

Investments - Program Related. Complete if the organization answered 'Yes' on Form 990, Part IV, line 11c. See Form 990, Part X, line 13.

(a) Description of investment	(b) Book value	(c) Method of valuation: Cost or end-of-year market value

(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
Total. (Column (b) must equal Form 990, Part X, col.(B) line 13.)

Part IX

Other Assets.
Complete if the organization answered 'Yes' on Form 990, Part IV, line 11d. See Form 990, Part X, line 15.

(a) Description				(b) Book value
(1)RIGHT OF USE ASSET				10,736,100
(2)SECURITY DEPOSIT				33,683
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
Total. (Column (b) must equal Form 990, Part X, col.(B) line 15.)...........				10,769,783

Part X

Other Liabilities.
Complete if the organization answered 'Yes' on Form 990, Part IV, line 11e or 11f. See Form 990, Part X, line 25.

1.(a) Description of liability	(b) Book value
(1) Federal income taxes
CURRENT PORTION OF OPERATING LEASE LIABILITY	2,394,262
OPERATING LEASE LIABILITY	9,290,916







Total. (Column (b) must equal Form 990, Part X, col.(B) line 25.)	11,685,178
2. Liability for uncertain tax positions. In Part XIII, provide the text of the footnote to the organization's financial statements that reports the organization's liability for uncertain tax positions under FIN 48 (ASC 740). Check here if the text of the footnote has been provided in Part XIII

Schedule D (Form 990) (Rev. 1-2025)

Page 4

Part XI Reconciliation of Revenue per Audited Financial Statements With Revenue per Return. Complete if the organization answered 'Yes' on Form 990, Part IV, line 12a.
1	Total revenue, gains, and other support per audited financial statements .......			1	9,886,945
2	Amounts included on line 1 but not on Form 990, Part VIII, line 12:
a	Net unrealized gains (losses) on investments ....	2a
b	Donated services and use of facilities .........	2b	375,000
c	Recoveries of prior year grants ...........	2c
d	Other (Describe in Part XIII.) ...........	2d
e	Add lines 2a through 2d .....................			2e	375,000
3	Subtract line 2e from line 1..................			3	9,511,945
4	Amounts included on Form 990, Part VIII, line 12, but not on line 1:
a	Investment expenses not included on Form 990, Part VIII, line 7b .	4a
b	Other (Describe in Part XIII.) ...........	4b
c	Add lines 4a and 4b....................			4c	0
5	Total revenue. Add lines 3 and 4c. (This must equal Form 990, Part I, line 12.) ......			5	9,511,945

Part XII Reconciliation of Expenses per Audited Financial Statements With Expenses per Return. Complete if the organization answered 'Yes' on Form 990, Part IV, line 12a.
1	Total expenses and losses per audited financial statements ...........			1	9,796,044
2	Amounts included on line 1 but not on Form 990, Part IX, line 25:
a	Donated services and use of facilities .........	2a	375,000
b	Prior year adjustments ............	2b
c	Other losses ................	2c
d	Other (Describe in Part XIII.) ...........	2d
e	Add lines 2a through 2d....................			2e	375,000
3	Subtract line 2e from line 1...................			3	9,421,044
4	Amounts included on Form 990, Part IX, line 25, but not on line 1:
a	Investment expenses not included on Form 990, Part VIII, line 7b ..	4a
b	Other (Describe in Part XIII.) ...........	4b
c	Add lines 4a and 4b.....................			4c	0
5	Total expenses. Add lines 3 and 4c. (This must equal Form 990, Part I, line 18.) ......			5	9,421,044

Part XIII

Supplemental Information

Provide the descriptions required for Part II, lines 3, 5, and 9; Part III, lines 1a and 4; Part IV, lines 1b and 2b; Part V, line 4; Part X, line 2; Part XI, lines 2d and 4b; and Part XII, lines 2d and 4b. Also complete this part to provide any additional information.

Return Reference	Explanation
PART X, LINE 2:	PER ASC 740-10, ALL TAX POSITIONS HAVE BEEN EVALUATED AND HAS BEEN DETERMINED THERE ARE NO UNCERTAIN TAX POSITIONS REQUIRING RECOGNITION OR DISCLOSURES.

Schedule D (Form 990) (Rev. 1-2025)

Additional Data

Software ID:
Software Version:

- TIN:

SCHEDULE G (Form 990)
(Rev. January 2025)

Department of the Treasury
Internal Revenue Service

Supplemental Information Regarding
Fundraising or Gaming Activities

Complete if the organization answered "Yes" on Form 990, Part IV, lines 17, 18, or 19, or if the organization entered more than $15,000 on Form 990-EZ, line 6a. Attach to Form 990 or Form 990-EZ.
Go to www.irs.gov/Form990 for instructions and the latest information.

OMB No. 1545-0047

Open to Public Inspection

Name of the organization
TISCH MULTIPLE SCLEROSIS RESEARCH CENTER
OF NEW YORK INC

Employer identification number

25-1922851

Part I

Fundraising Activities.Complete if the organization answered "Yes" on Form 990, Part IV, line 17.

Form 990-EZ filers are not required to complete this part.

Indicate whether the organization raised funds through any of the following activities. Check all that apply.

a	Mail solicitations	e	Solicitation of non-government grants
b	Internet and email solicitations	f	Solicitation of government grants
c	Phone solicitations	g	Special fundraising events
d	In-person solicitations

Did the organization have a written or oral agreement with any individual (including officers, directors, trustees

or key employees listed in Form 990, Part VII) or entity in connection with professional fundraising services?

YesNo

If "Yes," list the 10 highest paid individuals or entities (fundraisers) pursuant to agreements under which the fundraiser is
to be compensated at least $5,000 by the organization.

(i) Name and address of individual or entity (fundraiser)	(iii) Did fundraiser have custody or control of contributions?
	Yes	No










Total . . . . . . . . . . . . . . . . . . . .

List all states in which the organization is registered or licensed to solicit contributions or has been notified it is exempt from registration or licensing.

For Paperwork Reduction Act Notice, see the Instructions for Form 990 or 990-EZ.

Cat. No. 50083H

Schedule G (Form 990) (Rev. 1-2025)

Page 2

Part II

Fundraising Events. Complete if the organization answered "Yes" on Form 990, Part IV, line 18, or reported more than $15,000 of fundraising event contributions and gross income on Form 990-EZ, lines 1 and 6b. List events with gross receipts greater than $5,000.

		(a) Event #1 ANNUAL GALA DINNER (event type)	(b) Event #2 (event type)	(c) Other events (total number)	(d) Total events (add col. (a) through col. (c))
1	Gross receipts . . . . .	3,992,743			3,992,743
2	Less: Contributions . . . .
3	Gross income (line 1 minus line 2) . . . . . .	3,992,743			3,992,743

4	Cash prizes . . . . .
5	Noncash prizes . . . .
6	Rent/facility costs . . . .
7	Food and beverages . . .
8	Entertainment . . . .
9	Other direct expenses . . .	334,983	334,983
10	Direct expense summary. Add lines 4 through 9 in column (d) . . . . . . . . . .		334,983
11	Net income summary. Subtract line 10 from line 3, column (d). . . . . . . . . .		3,657,760

Part III

Gaming. Complete if the organization answered "Yes" on Form 990, Part IV, line 19, or reported more than $15,000 on Form 990-EZ, line 6a.

		(a) Bingo	(b) Pull tabs/Instant bingo/progressive bingo	(c) Other gaming	(d) Total gaming (add col.(a) through col.(c))
1	Gross revenue . . . . .

2	Cash prizes . . . . .
3	Noncash prizes . . . .
4	Rent/facility costs . . . .
5	Other direct expenses . . .

Volunteer labor . . . .

	Yes %
	No

	Yes %
	No

	Yes %
	No

Direct expense summary. Add lines 2 through 5 in column (d) . . . . . . . . . .

Net gaming income summary. Subtract line 7 from line 1, column (d). . . . . . . . .

Enter the state(s) in which the organization conducts gaming activities:

Is the organization licensed to conduct gaming activities in each of these states? . . . . . . . .

YesNo

If "No," explain:

10a

Were any of the organization's gaming licenses revoked, suspended or terminated during the tax year? . . .

YesNo

If "Yes," explain:

Schedule G (Form 990) (Rev. 1-2025)

Page 3

Does the organization conduct gaming activities with nonmembers? . . . . . . . . . . .

YesNo

Is the organization a grantor, beneficiary or trustee of a trust or a member of a partnership or other entity

formed to administer charitable gaming? . . . . . . . . . . . . . . . . .

YesNo

Indicate the percentage of gaming activity conducted in:

The organization's facility . . . . . . . . . . . . . . . . . .

13a

An outside facility . . . . . . . . . . . . . . . . . . . .

13b

Enter the name and address of the person who prepares the organization's gaming/special events books and records:

Name

Address

15a

Does the organization have a contract with a third party from whom the organization receives gaming

revenue? . . . . . . . . . . . . . . . . . . . . . . . .

YesNo

If "Yes," enter the amount of gaming revenue received by the organization $ and the

amount of gaming revenue retained by the third party $ .

If "Yes," enter name and address of the third party:

Name

Address

Gaming manager information:

Name

Gaming manager compensation $

Description of services provided

Director/officer Employee Independent contractor

Mandatory distributions:

Is the organization required under state law to make charitable distributions from the gaming proceeds to

retain the state gaming license? . . . . . . . . . . . . . . . . . . .

YesNo

Enter the amount of distributions required under state law distributed to other exempt organizations or spent

in the organization's own exempt activities during the tax year $

Part IV

Supplemental Information. Provide the explanations required by Part I, line 2b, columns (iii) and (v); and Part III, lines 9, 9b, 10b, 15b, 15c, 16, and 17b, as applicable. Also provide any additional information. See instructions.

Return Reference	Explanation

Schedule G (Form 990) (Rev. 1-2025)

Additional Data

Software ID:
Software Version:

- TIN:

Schedule J
(Form 990)
(Rev. January 2025)

Department of the Treasury
Internal Revenue Service

Compensation Information

For certain Officers, Directors, Trustees, Key Employees, and Highest
Compensated Employees
Complete if the organization answered "Yes" on Form 990, Part IV, line 23.
Attach to Form 990.
Go to www.irs.gov/Form990 for instructions and the latest information.

OMB No. 1545-0047

Open to Public Inspection

Name of the organization

TISCH MULTIPLE SCLEROSIS RESEARCH CENTER
OF NEW YORK INC

Employer identification number

25-1922851

Part I

Questions Regarding Compensation

Yes

Check the appropiate box(es) if the organization provided any of the following to or for a person listed on Form
990, Part VII, Section A, line 1a. Complete Part III to provide any relevant information regarding these items.

First-class or charter travel Housing allowance or residence for personal use

Travel for companions Payments for business use of personal residence

Tax idemnification and gross-up payments Health or social club dues or initiation fees

Discretionary spending account Personal services (e.g., maid, chauffeur, chef)

If any of the boxes on Line 1a are checked, did the organization follow a written policy regarding payment or reimbursement or provision of all of the expenses described above? If "No," complete Part III to explain .....

Did the organization require substantiation prior to reimbursing or allowing expenses incurred by all
directors, trustees, officers, including the CEO/Executive Director, regarding the items checked on Line 1a? ....

Indicate which, if any, of the following the filing organization used to establish the compensation of the
organization's CEO/Executive Director. Check all that apply. Do not check any boxes for methods
used by a related organization to establish compensation of the CEO/Executive Director, but explain in Part III.

Compensation committee Written employment contract

Independent compensation consultant Compensation survey or study

Form 990 of other organizations Approval by the board or compensation committee

During the year, did any person listed on Form 990, Part VII, Section A, line 1a, with respect to the filing organization or a related organization:

Receive a severance payment or change-of-control payment? .............

Participate in, or receive payment from, a supplemental nonqualified retirement plan? .........

Participate in, or receive payment from, an equity-based compensation arrangement? .........

If "Yes" to any of lines 4a-c, list the persons and provide the applicable amounts for each item in Part III.

Only 501(c)(3), 501(c)(4), and 501(c)(29) organizations must complete lines 5-9.

For persons listed on Form 990, Part VII, Section A, line 1a, did the organization pay or accrue any
compensation contingent on the revenues of:

The organization? ....................

Any related organization? .......................

If "Yes," on line 5a or 5b, describe in Part III.

For persons listed on Form 990, Part VII, Section A, line 1a, did the organization pay or accrue any
compensation contingent on the net earnings of:

The organization? ..................

Any related organization? ......................

If "Yes," on line 6a or 6b, describe in Part III.

For persons listed on Form 990, Part VII, Section A, line 1a, did the organization provide any nonfixed
payments not described in lines 5 and 6? If "Yes," describe in Part III ............

Were any amounts reported on Form 990, Part VII, paid or accured pursuant to a contract that was
subject to the initial contract exception described in Regulations section 53.4958-4(a)(3)? If "Yes," describe
in Part III ..........................

If "Yes" on line 8, did the organization also follow the rebuttable presumption procedure described in Regulations section 53.4958-6(c)? .........................

For Paperwork Reduction Act Notice, see the Instructions for Form 990.

Cat. No. 50053T

Schedule J (Form 990) (Rev. 1-2025)

Page 2

Part II

Officers, Directors, Trustees, Key Employees, and Highest Compensated Employees. Use duplicate copies if additional space is needed.

For each individual whose compensation must be reported on Schedule J, report compensation from the organization on row (i) and from related organizations, described in the
instructions, on row (ii). Do not list any individuals that are not listed on Form 990, Part VII.
Note. The sum of columns (B)(i)-(iii) for each listed individual must equal the total amount of Form 990, Part VII, Section A, line 1a, applicable column (D) and (E) amounts for that individual.

(A) Name and Title		(B) Breakdown of W-2, 1099-MISC compensation, and/or 1099-NEC			(C) Retirement and other deferred compensation	(D) Nontaxable benefits	(E) Total of columns (B)(i)-(D)	(F) Compensation in column (B) reported as deferred on prior Form 990
(A) Name and Title		(i) Base compensation	(ii) Bonus & incentive compensation	(iii) Other reportable compensation	(C) Retirement and other deferred compensation	(D) Nontaxable benefits	(E) Total of columns (B)(i)-(D)
1AMANDA B OPPENHEIMER CHIEF OPERATING OFFICER	(i) (ii)	177,186 ------------- 0	0 ------------- 0	0 ------------- 0	14,734 ------------- 0	0 ------------- 0	191,920 ------------- 0	0 ------------- 0
2TALENE KELLY DIRECTOR OF DEVELOPMENT	(i) (ii)	145,206 ------------- 0	0 ------------- 0	0 ------------- 0	5,589 ------------- 0	0 ------------- 0	150,795 ------------- 0	0 ------------- 0
3VIOLAINE HARRIS SENIOR RESEARCH SCIENTIST	(i) (ii)	255,540 ------------- 0	0 ------------- 0	0 ------------- 0	16,563 ------------- 0	0 ------------- 0	272,103 ------------- 0	0 ------------- 0
4JERRY LIN SENIOR STAFF ASSOCIATE	(i) (ii)	135,882 ------------- 0	0 ------------- 0	0 ------------- 0	10,951 ------------- 0	0 ------------- 0	146,833 ------------- 0	0 ------------- 0
5JAMIE WONG RESEARCH SCIENTIST	(i) (ii)	148,790 ------------- 0	0 ------------- 0	0 ------------- 0	11,887 ------------- 0	0 ------------- 0	160,677 ------------- 0	0 ------------- 0

Schedule J (Form 990) (Rev. 1-2025)

Page 3

Part III

Supplemental Information

Provide the information, explanation, or descriptions required for Part I, lines 1a, 1b, 3, 4a, 4b, 4c, 5a, 5b, 6a, 6b, 7, and 8, and for Part II. Also complete this part for any additional information.

Return Reference	Explanation

Schedule J (Form 990) (Rev. 1-2025)

Additional Data

Software ID:
Software Version:

- TIN:

Schedule L
(Form 990)
(Rev. January 2025)

Department of the Treasury
Internal Revenue Service

Transactions with Interested Persons

Complete if the organization answered "Yes" on Form 990, Part IV, lines 25a, 25b, 26, 27, 28a, 28b, or 28c, or Form 990-EZ, Part V, line 38a or 40b.
Attach to Form 990 or Form 990-EZ.
Go to www.irs.gov/Form990 for instructions and the latest information.

OMB No. 1545-0047

Open to Public Inspection

Name of the organization

TISCH MULTIPLE SCLEROSIS RESEARCH CENTER
OF NEW YORK INC

Employer identification number

25-1922851

Part I

Excess Benefit Transactions (section 501(c)(3), section 501(c)(4), and section 501(c)(29) organizations only).
Complete if the organization answered "Yes" on Form 990, Part IV, line 25a or 25b, or Form 990-EZ, Part V, line 40b.

1(a) Name of disqualified person	(c) Description of transaction	(d) Corrected?
1(a) Name of disqualified person	(c) Description of transaction	Yes	No

Enter the amount of tax incurred by the organization managers or disqualified persons during the year under section 4958. ........................... $

Enter the amount of tax, if any, on line 2, above, reimbursed by the organization ........ $

Part II

Loans to and/or From Interested Persons.
Complete if the organization answered "Yes" on Form 990-EZ, Part V, line 38a, or Form 990, Part IV, line 26; or if the organization reported an amount on Form 990, Part X, line 5, 6, or 22

(a) Name of interested person	(b) Relationship with organization	(c) Purpose of loan	(d) Loan to or from the organization?		(e) Original principal amount	(f) Balance due	(g) In default?		(h) Approved by board or committee?		(i) Written agreement?
(a) Name of interested person	(b) Relationship with organization	(c) Purpose of loan	To	From	(e) Original principal amount	(f) Balance due	Yes	No	Yes	No	Yes	No
(1) INT'L MS MGT PRACTICE	DR SADIQ IS 100% SH	SHARED COSTS	X		100,000	22,475		No	Yes			No



Total ............... $						22,475

Part III

Grants or Assistance Benefiting Interested Persons.
Complete if the organization answered "Yes" on Form 990, Part IV, line 27.

(a) Name of interested person	(b) Relationship between interested person and the organization	(c) Amount of assistance	(d) Type of assistance	(e) Purpose of assistance

For Paperwork Reduction Act Notice, see the Instructions for Form 990 or 990-EZ.

Cat. No. 50056A

Schedule L (Form 990) (Rev. 1-2025)

Page 2

Part IV

Business Transactions Involving Interested Persons.
Complete if the organization answered "Yes" on Form 990, Part IV, line 28a, 28b, or 28c.

(a) Name of interested person	(b) Relationship between interested person and the organization	(c) Amount of transaction	(d) Description of transaction	(e) Sharing of organization's revenues?
(a) Name of interested person		(c) Amount of transaction	(d) Description of transaction	Yes	No
(1) INT'L MS MGT PRACTICE OF NY PC	DR SADIQ IS 100% SH OF PRACTICE	2,885,680	RENT, SHARED EXPENSES, CLINICAL SAMPLES AND PROCEDURES		No

Part V

Supplemental Information
Provide additional information for responses to questions on Schedule L (see instructions).

Return Reference	Explanation

Schedule L (Form 990) (Rev. 1-2025)

Additional Data

Software ID:
Software Version:

- TIN:

SCHEDULE M
(Form 990)

Department of the Treasury

Internal Revenue Service

Noncash Contributions

Complete if the organizations answered "Yes" on Form 990, Part IV, lines 29 or 30.
Attach to Form 990.
Go to www.irs.gov/Form990 for the latest information.

OMB No. 1545-0047

2025

Open to Public Inspection

Name of the organization

TISCH MULTIPLE SCLEROSIS RESEARCH CENTER
OF NEW YORK INC

Employer identification number

25-1922851

Part I

Types of Property

	(a) Check if applicable	(b) Number of contributions or items contributed	(c) Noncash contribution amounts reported on Form 990, Part VIII, line 1g	(d) Method of determining noncash contribution amounts
1 Art—Works of art ....
2 Art—Historical treasures .
3 Art—Fractional interests ..
4 Books and publications ..
5 Clothing and household goods .......
6 Cars and other vehicles ..
7 Boats and planes ....
8 Intellectual property ...
9 Securities—Publicly traded .	X	10	265,852	FAIR MARKET VALUE
10 Securities—Closely held stock .
11 Securities—Partnership, LLC, or trust interests ....
12 Securities—Miscellaneous ..
13 Qualified conservation contribution—Historic structures .....
14 Qualified conservation contribution—Other ...
15 Real estate—Residential .
16 Real estate—Commercial ..
17 Real estate—Other ...
18 Collectibles .....
19 Food inventory ...
20 Drugs and medical supplies .
21 Taxidermy ......
22 Historical artifacts ....
23 Scientific specimens ..
24 Archeological artifacts ...
25 Other ( )
26 Other ( )
27 Other ( )
28 Other ( )

Number of Forms 8283 received by the organization during the tax year for contributions
for which the organization completed Form 8283, Part IV, Donee Acknowledgement

Yes

30a

During the year, did the organization receive by contribution any property reported in Part I, lines 1 through 28, that it must hold for at least three years from the date of the initial contribution, and which isn't required to be used for exempt purposes for the entire holding period? ...................

30a

If "Yes," describe the arrangement in Part II.

Does the organization have a gift acceptance policy that requires the review of any nonstandard contributions?

Yes

32a

Does the organization hire or use third parties or related organizations to solicit, process, or sell noncash

contributions? ..........................

32a

Yes

If "Yes," describe in Part II.

If the organization didn't report an amount in column (c) for a type of property for which column (a) is checked,

describe in Part II.

For Paperwork Reduction Act Notice, see the Instructions for Form 990.

Cat. No. 51227J

Schedule M (Form 990) (2025)

Page 2

Part IISupplemental Information. Provide the information required by Part I, lines 30b, 32b, and 33, and whether the organization is reporting in Part I, column (b), the number of contributions, the number of items received, or a combination of both. Also complete this part for any additional information.

Return Reference	Explanation
PART I, LINE 32B:	STOCK IS GIFTED TO THE RESEARCH CENTER. THE BENEFACTOR TRANSFERS TITLE TO WELLS FARGO, WHO THEN SELLS THE GIFTED STOCK ON THE OPEN MARKET.

Schedule M (Form 990) (2025)

Additional Data

Software ID:
Software Version:

- TIN:

SCHEDULE O
(Form 990)
(Rev. January 2025)
Department of the Treasury
Internal Revenue Service

Supplemental Information to Form 990 or 990-EZ

Complete to provide information for responses to specific questions on
Form 990 or 990-EZ or to provide any additional information.
Attach to Form 990 or 990-EZ.
Go to www.irs.gov/Form990 for instructions and the latest information.

OMB No. 1545-0047

Open to Public
Inspection

Name of the organization

TISCH MULTIPLE SCLEROSIS RESEARCH CENTER
OF NEW YORK INC

Employer identification number

25-1922851

Return Reference	Explanation
FORM 990, PART I, LINE 1	THE PURPOSE OF TISCH MULTIPLE SCLEROSIS RESEARCH CENTER OF NY, INC. IS TO CONDUCT MEDICAL RESEARCH DIRECTED TOWARD FINDING THE CAUSE AND EVENTUAL CURE FOR MULTIPLE SCLEROSIS.
FORM 990, PART III, LINE 4A	TISCH MS RESEARCH CENTER OF NEW YORK'S (TISCH MSRCNY) MISSION IS TO CONDUCT MEDICAL RESEARCH DIRECTED TOWARD DISCOVERING THE CAUSE OF AND EVENTUAL CURE FOR MULTIPLE SCLEROSIS. THESE RESEARCH INITIATIVES INCLUDE: TO BETTER UNDERSTAND AND TREAT COORDINATION AND BALANCE DIFFICULTIES IN PATIENTS WITH MS. TO CREATE AN EXPERIMENTAL MODEL OF PROGRESSIVE MS THAT WILL ENABLE US TO BETTER UNDERSTAND AND TREAT PATIENTS WITH SECONDARY PROGRESSIVE MS (SPMS) AND PRIMARY PROGRESSIVE MS (PPMS). TO UTILIZE NOVEL CEREBROSPINAL FLUID BASED ANIMAL MODELS TO BETTER UNDERSTAND OTHER NEURODEGENERATIVE DISEASES SUCH AS MS AND ALS. TO DEVELOP ORGANOID MODELS TO BETTER UNDERSTAND THE UNDERPINNINGS OF PROGRESSIVE MS. FINALLY, AND PERHAPS MOST IMPORTANTLY, TO IDENTIFY THE INITIAL TRIGGER(S) THAT CAUSE MS. IN 2025, DRS WONG AND SADIQ PUBLISHED RESULTS FROM A COLLABORATION WITH NEURON23, INC. IN THE PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES. THE STUDY USED THE PPMS ANIMAL MODEL DEVELOPED AT TISCH MS TO DEMONSTRATE PROOF OF CONCEPT OF A NOVEL MS THERAPEUTIC. IN 2025, TISCH MSRCNY RESEARCHERS WERE INVITED TO PRESENT RESEARCH ABSTRACTS AT THE ANNUAL CONFERENCES OF ACTRIMS (AMERICAS COMMITTEE FOR TREATMENT AND RESEARCH IN MS), THE AMERICAN ADADEMY OF NEUROLOGY AND THE SOCIETY FOR NEUROSCIENCE.
FORM 990, PART III, LINE 4B	AS AN ACADEMIC FACILITY, THE TISCH MS RESEARCH CENTER PROVIDES EDUCATIONAL AND TRAINING RESOURCES FOR MS RESEARCHERS AND MEDICAL PROFESSIONALS. ONE OF THE MOST IMPORTANT GOALS OF TISCH MSRCNY IS TO PROVIDE RESEARCH OPPORTUNITIES FOR YOUNG SCIENCE GRADUATES THAT ENABLE THEM TO BECOME CAREER SCIENTISTS. SINCE ITS INCEPTION, THEY HAVE TRAINED OVER 100 COLLEGE GRADUATES AS RESEARCH ASSISTANTS (RAS) FOR 2-YEAR ROTATIONS. IN 2025, ALL SECOND YEAR RESEARCH ASSISTANTS, UNDER THE GUIDANCE OF TISCH MSRCNY PRINCIPAL INVESTIGATORS, MATRICULATED TO TOP MEDICAL SCHOOLS AND GRADUATE PROGRAMS. FELLOWSHIPS IN MS RESEARCH ARE ALSO OFFERED TO PHYSICIANS AND SCIENTISTS INTERESTED IN ENTERING OR EXPANDING THEIR WORK IN THIS FIELD. WEEKLY JOURNAL CLUB MEETINGS OR GRAND ROUNDS TAKE PLACE IN OUR CONFERENCE ROOM TO DISCUSS THE LATEST ADVANCEMENTS IN MS RESEARCH AND HOW IT APPLIES TO OUR CURRENT INVESTIGATIONS.
FORM 990, PART VI, SECTION A, LINE 2	THE FOLLOWING DIRECTORS ARE RELATED AS HUSBAND AND WIFE: THOMAS AND MUSA MAYER CLIFFORD AND BONNIE EISLER RICHARD AND GRETA RUBIN SCHWARTZ JAMES AND BERNADETTE MARIANI DEVEN AND MONIKA PAREKH PHIL AND ALLA WEISBERG DANIEL AND BONNIE TISCH
FORM 990, PART VI, SECTION A, LINE 4	CHANGES TO BYLAWS: ARTICLE II, SECTION 2(B) "ENTIRE BOARD" DEFINITION EXPANDED TO EXPLICITLY BE DEFINED AS "THE TOTAL NUMBER OF DIRECTORS ENTITLED TO VOTE WHICH THE CORPORATION WOULD HAVE IF THERE WERE NO VACANCIES, AND INCLUDES "THE TERMS OF ANY DIRECTORS WHOSE TERMS HAVE NOT YET EXPIRED." ARTICLE II, SECTION 3 MEETING SUCCESSION HAS BEEN CLARIFIED. IF BOTH THE CHAIR AND VICE CHAIR(S) ARE ABSENT, A DIRECTOR DESIGNATED BY THE CHAIR WHO IS ON THE EXECUTIVE COMMITTEE PRESIDES (BEFORE DEFAULTING TO A DIRECTOR CHOSEN BY MAJORITY). THE PREVIOUS BYLAWS WENT FROM VICE CHAIR TO MAJORITY-CHOSEN DIRECTOR. ARTICLE II, SECTION 4 REMOVAL OF A DIRECTOR NOW REQUIRES CAUSE. THIS HAS BEEN CHANGED FROM "WITH OR WITHOUT CAUSE" TO "WITH CAUSE" BY MAJORITY OF THE ENTIRE BOARD. ARTICLE II, SECTION 6 VIRTUAL MEETINGS EXPLICITLY AUTHORIZED WITH NEW LANGUAGE: MEETINGS MAY BE HELD "INCLUDING VIRTUALLY." ARTICLE II, SECTION 6 NOTICE METHODS NARROWED. THE PREVIOUS BYLAWS ALLOWED NOTICE ORALLY (1 DAY), OR BY FAX/EMAIL/MAIL (3 DAYS). THE NEW BYLAWS ALLOW ONLY EMAIL, MAIL, OR COURIER, ALL WITH A UNIFORM 3-DAY NOTICE. ORAL, TELEPHONE, AND FAX NOTICE ARE ELIMINATED. ARTICLE II, SECTION 6 "WITHOUT NOTICE" LANGUAGE FOR REGULAR MEETINGS HAS BEEN REMOVED. ARTICLE II, SECTION 8 ADJOURNMENT NOW REQUIRES NOTICE. PREVIOUSLY, AN ADJOURNED MEETING COULD BE MOVED "WITHOUT NOTICE TO ANY DIRECTOR." THE NEW BYLAWS REQUIRE NOTICE FROM DIRECTORS NOT PRESENT AT THE ADJOURNMENT UNLESS ANNOUNCED AT THE MEETING. ARTICLE II, SECTION 9(A) RECUSED DIRECTORS COUNT TOWARD QUORUM. NEW PROVISION: DIRECTORS PRESENT BUT NOT VOTING DUE TO A CONFLICT OF INTEREST OR RELATED-PARTY TRANSACTION ARE STILL "PRESENT" FOR QUORUM PURPOSES AT THE TIME OF THE VOTE. ARTICLE II, SECTION 9(B) THE PREVIOUS BYLAWS ALLOWED REAL PROPERTY TRANSACTIONS NOT REQUIRING BOARD APPROVAL TO BE APPROVED BY A COMMITTEE. NEW LANGUAGE ON THE CHANGED BYLAWS NOW REQUIRES A MAJORITY VOTE OF THE BOARD OR A COMMITTEE FOR ANY SUCH "OTHER" REAL PROPERTY TRANSACTION. ARTICLE II, SECTION 10 ANNUAL REPORT PRESENTER CHANGED. THE PREVIOUS BYLAWS HAD THE BOARD PRESENT THE REPORT, CERTIFIED BY INDEPENDENT ACCOUNTANTS. THE NEW BYLAWS HAVE THE PRESIDENT AND TREASURER PRESENT THE ANNUAL REPORT AND ALLOW VERIFICATION BY THE P&T OR A MAJORITY OF DIRECTORS AS AN ALTERNATIVE TO CERTIFICATION BY INDEPENDENT ACCOUNTANTS. ARTICLE II, SECTION 11(B) TREASURER MAY DELEGATE. ADDED OR THEIR DESIGNATE" TO THE TREASURER'S ANNUAL DONOR-RESTRICTED ASSET REPORTING DUTY. ARTICLE III, SECTION 1 HEIGHTENED THRESHOLD FOR EXECUTIVE COMMITTEE APPOINTMENTS ON LARGE BOARDS. WHEN THE BOARD HAS 30 OR MORE MEMBERS, EXECUTIVE COMMITTEE APPOINTMENTS NOW REQUIRE THREE-QUARTERS OF THE DIRECTORS TO BE PRESENT RATHER THAN A SIMPLE MAJORITY OF THE ENTIRE BOARD. ARTICLE III, SECTION 1 SIGNIFICANTLY EXPANDED LIST OF ACTIONS COMMITTEES CANNOT TAKE. NEW RESTRICTIONS ADDED BEYOND THE ORIGINAL FOUR: (E) ELECTING OR REMOVING OFFICERS AND DIRECTORS, (F) APPROVING MERGERS OR PLANS OF DISSOLUTION, (G) AUTHORIZING SALE/LEASE/DISPOSITION OF ALL OR SUBSTANTIALLY ALL ASSETS, AND (H) APPROVING AMENDMENTS TO THE CERTIFICATE OF INCORPORATION. ARTICLE III, SECTION 2 NON-DIRECTORS MAY SERVE ON COMMITTEES OF THE CORPORATION. NEW LANGUAGE EXPLICITLY PERMITS NON-DIRECTORS TO SERVE ON THESE (NON-BOARD) COMMITTEES. ARTICLE III, SECTION 4 NOMINATING COMMITTEE ROLE CLARIFIED. THE COMMITTEE NOW PRESENTS NOMINEES "FOR THEM [THE BOARD] TO VOTE UPON" RATHER THAN "FOR NOMINATION." ARTICLE IV, SECTION 8 BACKUP PRESIDER WHEN NO VICE CHAIR. IF THERE IS NO VICE CHAIR, A MEMBER OF THE EXECUTIVE COMMITTEE SELECTED BY THE BOARD PRESIDES. ARTICLE IV, SECTION 9 TREASURER'S ROLE REMOVED THE BOND REQUIREMENT ("IF REQUIRED BY THE BOARD OBTAIN A BOND"). ADDED NEW OVERSIGHT RESPONSIBILITIES SUCH AS, ASSISTING THE BOARD WITH FINANCIAL OVERSIGHT AND LEGAL/REGULATORY COMPLIANCE, WORKING "IN CONJUNCTION WITH THE AUDIT COMMITTEE," ENSURING SOUND FINANCIAL PRACTICES AND TIMELY REPORTING, AND A "KEY ROLE" IN BUDGETING, FINANCIAL PLANNING, AND MONITORING FISCAL POLICIES. EXPLICITLY ALLOWS THE TREASURER TO DELEGATE BOOKKEEPING/CUSTODY DUTIES TO STAFF. ARTICLE IV, SECTION 10 NEW PARAGRAPH PERMITS THE SECRETARY TO DELEGATE DUTIES TO STAFF WHILE RETAINING OVERALL RESPONSIBILITY. ARTICLE VII, SECTION 3 ADVANCEMENT OF EXPENSES HAVE BEEN MODIFIED TO INCLUDE TWO NEW CONDITIONS: (1) THE BOARD MUST DETERMINE THE PERSON WAS ACTING IN GOOD FAITH BEFORE ADVANCING EXPENSES, AND (2) THE REPAYMENT OBLIGATION NOW ALSO COVERS SITUATIONS "WHERE INDEMNIFICATION IS GRANTED, TO THE EXTENT THE EXPENSES SO ADVANCED EXCEED THE INDEMNIFICATION TO WHICH HE/SHE IS ENTITLED." ARTICLE VIII, SECTION 2 WHISTLEBLOWER POLICY IS NOW REQUIRED. THE LIST OF POLICIES THE BOARD MUST ADOPT NOW EXPLICITLY INCLUDES A WHISTLEBLOWER POLICY IN ADDITION TO A CONFLICTS OF INTEREST POLICY WHILE ALSO ADDING "AS ARE REQUIRED BY LAW" TO THE POLICIES THE BOARD MUST ADOPT. ARTICLE VIII, SECTION 3 BOOKS AND RECORDS SCOPE HAVE BEEN BROADENED TO NOW REQUIRE MINUTES TO COVER "ANY COMMITTEES OF THE BOARD" RATHER THAN ONLY "ANY STANDING COMMITTEES OF THE BOARD."
FORM 990, PART VI, SECTION B, LINE 11B	WHEN FORM 990 IS PRESENTED TO THE ORGANIZATION, THE AUDIT COMMITTEE WILL REVIEW AND SEND IT TO THE BOARD FOR COMMENT. IF NONE IS RECEIVED IN 7 DAYS, THE RETURN IS FILED.
FORM 990, PART VI, SECTION B, LINE 12C	THE BOARD MEMBERS COMPLETE AN "ANNUAL CONFLICT OF INTEREST DISCLOSURE STATEMENT."
FORM 990, PART VI, SECTION B, LINE 15	COMPENSATION IS DETERMINED USING PUBLICLY AVAILABLE COMPENSATION INFORMATION FROM COMPARABLE RESEARCH ORGANIZATIONS AND UNIVERSITIES, WHICH IS REVIEWED AND APPROVED BY DR. SADIQ. COMPENSATION IS DETERMINED USING PUBLICLY AVAILABLE COMPENSATION INFORMATION FROM COMPARABLE RESEARCH ORGANIZATIONS AND UNIVERSITIES, WHICH IS REVIEWED AND APPROVED BY DR. SADIQ.
FORM 990, PART VI, SECTION C, LINE 19	THE ORGANIZATION'S WEBSITE WILL DISPLAY THE FINANCIALS AND FORM 990 FOR PUBLIC VIEWING. IN ADDITION, BOTH THE FINANCIALS AND FORM 990 ARE AVAILABLE UPON REQUEST.
FORM 990, PART XII, LINE 2C:	THE PROCESS OF OVERSEEING THE AUDIT AND SELECTION OF INDEPENDENT ACCOUNTANT'S HAS NOT BEEN CHANGED FROM PRIOR YEAR.
PT XI: GIFTS IN KIND - GOODS AND MATERIALS	OTHER: REQUIRED DISCLOSURE OF NON-CASH SECURITIES FROM ANONYMOUS DONORS TOTALING $9,903.

For Paperwork Reduction Act Notice, see the Instructions for Form 990 or 990-EZ.

Cat. No. 51056K

Schedule O (Form 990) (Rev. 1-2025)

Additional Data

Software ID:
Software Version:

		Prior Year	Current Year
8	Contributions and grants (Part VIII, line 1h) .........	5,576,393	5,829,026
9	Program service revenue (Part VIII, line 2g) .........	247,000	31,939
10	Investment income (Part VIII, column (A), lines 3, 4, and 7d ) ....	-16,378	-6,780
11	Other revenue (Part VIII, column (A), lines 5, 6d, 8c, 9c, 10c, and 11e)	4,565,248	3,657,760
12	Total revenue—add lines 8 through 11 (must equal Part VIII, column (A), line 12)	10,372,263	9,511,945
13	Grants and similar amounts paid (Part IX, column (A), lines 1–3 )...	0	0
14	Benefits paid to or for members (Part IX, column (A), line 4).....	0	0
15	Salaries, other compensation, employee benefits (Part IX, column (A), lines 5–10)	3,585,538	3,273,559
16a	Professional fundraising fees (Part IX, column (A), line 11e) .....	0	0
b	Total fundraising expenses (Part IX, column (D), line 25) 747,765
17	Other expenses (Part IX, column (A), lines 11a–11d, 11f–24e)....	7,102,504	6,147,484
18	Total expenses. Add lines 13–17 (must equal Part IX, column (A), line 25)	10,688,042	9,421,043
19	Revenue less expenses. Subtract line 18 from line 12.......	-315,779	90,902
		Beginning of Current Year	End of Year
20	Total assets (Part X, line 16).............	29,507,214	27,670,515
21	Total liabilities (Part X, line 26).............	14,293,531	12,361,206
22	Net assets or fund balances. Subtract line 21 from line 20.....	15,213,683	15,309,309

Sign Here

	Signature of officer	Date

	Type or print name and title


4a	(Code: ) (Expenses $ 7,540,138 including grants of $ ) (Revenue $ 9,518,725 )
	SEE SCHEDULE O.

4b	(Code: ) (Expenses $ 6,672 including grants of $ ) (Revenue $ )
	SEE SCHEDULE O.

4c	(Code: ) (Expenses $ including grants of $ ) (Revenue $ )












4d	Other program services (Describe in Schedule O.)
	(Expenses $ including grants of $ ) (Revenue $ )
4e	Total program service expenses7,546,810

1b	Sub-Total..............
c	Total from continuation sheets to Part VII, Section A..
d	Total (add lines 1b and 1c).........	862,604	0	59,724

		Business Code
2a	GENE THERAPY PROGRAM	621500	31,939	31,939	0	0
b
c
d
e
f	All other program service revenue.
g	Total. Add lines 2a–2f .....		31,939

1	Briefly describe the organization’s mission or most significant activities: SEE SCHEDULE O.
2	Check this box
3	Number of voting members of the governing body (Part VI, line 1a) ........	3	31
4	Number of independent voting members of the governing body (Part VI, line 1b) .....	4	30
5	Total number of individuals employed in calendar year 2025 (Part V, line 2a) ......	5	38
6	Total number of volunteers (estimate if necessary) .............	6	0
7a	Total unrelated business revenue from Part VIII, column (C), line 12 ........	7a	0
b	Net unrelated business taxable income from Form 990-T, Part I, line 11 .........	7b	0

1a	Federated campaigns..		1a
b	Membership dues..		1b
c	Fundraising events..		1c
d	Related organizations		1d
e	Government grants (contributions)		1e

f	All other contributions, gifts, grants, and similar amounts not included above		1f	5,829,026

g	Noncash contributions included in lines 1a - 1f:$		1g	265,851

h Total. Add lines 1a-1f.......		5,829,026

3 Investment income (including dividends, interest, and othersimilar amounts) ......			226			226
4 Income from investment of tax-exempt bond proceeds
5 Royalties...........
			(i) Real	(ii) Personal
6a	Gross rents	6a
b	Less: rental expenses	6b
c	Rental income or (loss)	6c
d	Net rental income or (loss).......
			(i) Securities	(ii) Other
7a	Gross amount from sales of assets other than inventory	7a	258,845
b	Less: cost or other basis and sales expenses	7b	265,851
c	Gain or (loss)	7c	-7,006
d	Net gain or (loss).........			-7,006	-7,006
8a	Gross income from fundraising events (not including $ of contributions reported on line 1c). See Part IV, line 18 ....
			8a	3,992,743
b	Less: direct expenses ...		8b	334,983
c	Net income or (loss) from fundraising events..			3,657,760			3,657,760
9a	Gross income from gaming activities. See Part IV, line 19 ...
			9a
b	Less: direct expenses ...		9b
c	Net income or (loss) from gaming activities..
10a	Gross sales of inventory, less returns and allowances ..
			10a
b	Less: cost of goods sold ..		10b
c	Net income or (loss) from sales of inventory..

Business Code
11a
b
c
d	All other revenue ....
e	Total. Add lines 11a–11d ......
12	Total revenue. See instructions.....			9,511,945	24,933	0	3,657,986

1	Grants and other assistance to domestic organizations and domestic governments. See Part IV, line 21 ....
2	Grants and other assistance to domestic individuals. See Part IV, line 22 ...........
3	Grants and other assistance to foreign organizations, foreign governments, and foreign individuals. See Part IV, lines 15 and 16. .............
4	Benefits paid to or for members .......
5	Compensation of current officers, directors, trustees, and key employees ...........
6	Compensation not included above, to disqualified persons (as defined under section 4958(f)(1)) and persons described in section 4958(c)(3)(B) .........
7	Other salaries and wages........	2,352,038	1,745,526	406,207	200,305
8	Pension plan accruals and contributions (include section 401(k) and 403(b) employer contributions) ....
9	Other employee benefits .......	680,750	493,907	129,072	57,771
10	Payroll taxes ...........	240,771	172,919	50,199	17,653
11	Fees for services (non-employees):
a	Management ......
b	Legal .........	37,812	21,329	16,483
c	Accounting ...........	33,736		33,736
d	Lobbying ...........
e	Professional fundraising services. See Part IV, line 17
f	Investment management fees ......
g	Other (If line 11g amount exceeds 10% of line 25, column (A) amount, list line 11g expenses on Schedule O)
12	Advertising and promotion ....
13	Office expenses .......	210,311	33,606	85,534	91,171
14	Information technology ......
15	Royalties ..
16	Occupancy ...........	2,814,982	2,250,997	282,805	281,180
17	Travel ............
18	Payments of travel or entertainment expenses for any federal, state, or local public officials .
19	Conferences, conventions, and meetings ....	29,539	29,539
20	Interest ...........	210		210
21	Payments to affiliates .......
22	Depreciation, depletion, and amortization ..	1,496,332	1,346,698	74,817	74,817
23	Insurance ...	118,530	72,736	37,203	8,591
24	Other expenses. Itemize expenses not covered above (List miscellaneous expenses in line 24e. If line 24e amount exceeds 10% of line 25, column (A) amount, list line 24e expenses on Schedule O.)
a	LAB SUPPLIES, SERVICES,	1,145,339	1,145,339	0	0
b	EQUIPMENT REPAIRS AND M	254,618	234,214	10,202	10,202
c	FUNDRAISING EXPENSE	6,075	0	0	6,075
d
e	All other expenses
25	Total functional expenses. Add lines 1 through 24e	9,421,043	7,546,810	1,126,468	747,765
26	Joint costs. Complete this line only if the organization reported in column (B) joint costs from a combined educational campaign and fundraising solicitation. Check here if following SOP 98-2 (ASC 958-720).

1	Cash–non-interest-bearing ........			3,040,370	1	3,520,301
2	Savings and temporary cash investments .........				2
3	Pledges and grants receivable, net ......			136,795	3	0
4	Accounts receivable, net .............			0	4	31,939
5	Loans and other receivables from any current or former officer, director, trustee, key employee, creator or founder, substantial contributor, or 35% controlled entity or family member of any of these persons .......
					5
6	Loans and other receivables from other disqualified persons (as defined under section 4958(f)(1)), and persons described in section 4958(c)(3)(B) ...
					6
7	Notes and loans receivable, net ...........				7
8	Inventories for sale or use ............				8
9	Prepaid expenses and deferred charges ......			663,966	9	621,831
10a	Land, buildings, and equipment: cost or other basis. Complete Part VI of Schedule D	10a	26,453,245
b	Less: accumulated depreciation	10b	13,726,584	12,603,060	10c	12,726,661
11	Investments—publicly traded securities .				11
12	Investments—other securities. See Part IV, line 11 .....				12
13	Investments—program-related. See Part IV, line 11 ..				13
14	Intangible assets ...............				14
15	Other assets. See Part IV, line 11 ...........			13,063,023	15	10,769,783
16	Total assets. Add lines 1 through 15 (must equal line 33)...			29,507,214	16	27,670,515

17	Accounts payable and accrued expenses .....	323,790	17	653,553
18	Grants payable ...		18
19	Deferred revenue .........		19
20	Tax-exempt bond liabilities .........		20
21	Escrow or custodial account liability. Complete Part IV of Schedule D		21
22	Loans and other payables to any current or former officer, director, trustee, key employee, creator or founder, substantial contributor, or 35% controlled entity or family member of any of these persons .........
			22	22,475
23	Secured mortgages and notes payable to unrelated third parties ..		23
24	Unsecured notes and loans payable to unrelated third parties ..		24
25	Other liabilities (including federal income tax, payables to related third parties, and other liabilities not included on lines 17 - 24). Complete Part X of Schedule D	13,969,741	25	11,685,178
26	Total liabilities. Add lines 17 through 25..	14,293,531	26	12,361,206

	Organizations that follow FASB ASC 958, check here and complete lines 27, 28, 32, and 33.
27	Net assets without donor restrictions ..........	15,213,683	27	15,182,794
28	Net assets with donor restrictions ...........	0	28	126,515
	Organizations that do not follow FASB ASC 958, check here and complete lines 29 through 33.
29	Capital stock or trust principal, or current funds .....		29
30	Paid-in or capital surplus, or land, building or equipment fund ...		30
31	Retained earnings, endowment, accumulated income, or other funds		31
32	Total net assets or fund balances ...........	15,213,683	32	15,309,309
33	Total liabilities and net assets/fund balances ........	29,507,214	33	27,670,515